ライフサイエンスコーパス: mammographic density

1 ere length and MDA in their association with mammographic density.

2 and breast cancer risk among women with low mammographic density.

3 ng carotenoids are inversely associated with mammographic density.

4 last four factors were associated with lower mammographic density.

5 women in the United Kingdom are reflected in mammographic density.

6 a reasonable intervention approach to reduce mammographic density.

7 vely associated (free estradiol) with higher mammographic density.

8 atistically significantly related to greater mammographic density.

9 orresponds to the collagen component at high mammographic density.

10 breast cancer risk is not fully explained by mammographic density.

11 he SNP most strongly associated with percent mammographic density.

12 associated with both breast cancer risk and mammographic density.

13 d by highest and lowest quartiles of percent mammographic density.

14 signaling has been associated with increased mammographic density.

15 .27 to 0.93) compared with women with stable mammographic density.

16 be partially due to negative confounding by mammographic density.

17 st cancer risk remained after adjustment for mammographic density.

18 n inverse association between involution and mammographic density.

19 er through a mechanism that includes reduced mammographic density.

20 otect against breast cancer is by decreasing mammographic density.

21 cer risk, particularly among women with high mammographic density.

22 isted thresholding method to measure percent mammographic density.

23 carotenoids and breast cancer risk varies by mammographic density.

24 breast cancer risk through its influence on mammographic density.

25 association between AR-CAG repeat length and mammographic density, a strong breast cancer risk factor

26 as tailored to lifetime risk (Gail test) and mammographic density (according to Breast Imaging Report

27 Percent mammographic density adjusted for age and body mass inde

28 High-percent mammographic density adjusted for age and body mass inde

29 We studied the change in mammographic density after a breast cancer diagnosis and

30 Previous studies have linked reductions in mammographic density after a breast cancer diagnosis to

31 A decrease in mammographic density after breast cancer diagnosis appea

32 treatment is associated with a reduction in mammographic density and an improved survival.

33 r evidence of a shared genetic basis between mammographic density and breast cancer and illustrate th

34 authors investigated the association between mammographic density and breast cancer risk among women

35 uate the strength of the association between mammographic density and breast cancer risk using differ

36 To maximize statistical power in studies of mammographic density and breast cancer, it is advantageo

37 ations of plasma leptin and adiponectin with mammographic density and disease status and assessed the

38 onectin levels were directly associated with mammographic density and HDL cholesterol and negatively

39 ons of the breast images to characterize the mammographic density and heterogeneity of dense portions

40 Mammographic density and lobular involution are both sig

41 requiring that women be informed about their mammographic density and related adjunct imaging.

42 e genome-wide association studies of percent mammographic density and report an association with rs10

43 At lower levels of MDA, mammographic density and telomere length were inversely

44 s evidence of a J-shaped association between mammographic density and telomere length.

45 n ERBB2 (HER2(+) or HER2(-)) tumor subtypes, mammographic density and tumor grade.

46 The associations are independent of BMI, mammographic density, and treatment.

47 Tumor size, mammographic density, and US characteristics may be indi

48 Ethnic differences in mammographic density are consistent with those for breas

49 e results provide new insights into how high mammographic density arises and why it is associated wit

50 le predictors of breast cancer risk, but few mammographic density-associated genetic variants have be

51 ingdom population-based multiethnic study of mammographic density at ages 50-64 years in 645 women.

52 The percent mammographic density at the first available mammogram wa

53 ated with a weaker annual decline in percent mammographic density by 0.09% (standard error = 0.03; P

54 We measured mammographic density by a computer assisted method and b

55 tatistically significant association between mammographic density change and survival.

56 Conversely, mammographic density does not appear to explain the inve

57 dy of the magnitude and meaning of increased mammographic density due to use of estrogen and estrogen

58 However, the extent to which change in mammographic density during adjuvant tamoxifen therapy c

59 Interval breast cancers in women with low mammographic density have the most aggressive phenotype.

60 larly, among women in the highest tertile of mammographic density, high levels of circulating alpha-c

61 countries in the International Consortium on Mammographic Density (ICMD).

62 Age-adjusted percent mammographic densities in Afro-Caribbeans and South Asia

63 hysical activity, body mass index (BMI), and mammographic density in a racially/ethnically diverse po

64 We examined the effect of CEE alone on mammographic density in a subsample of the Women's Healt

65 conjugated equine estrogens (CEEs) alone on mammographic density in diverse racial/ethnic population

66 st prominent difference between low and high mammographic density in healthy breast tissue by PARADIG

67 y measured circulating carotenoid levels and mammographic density in the Nurses' Health Study.

68 High mammographic density is a strong breast cancer risk fact

69 Mammographic density is a strong risk factor for breast

70 Extensive mammographic density is a strong risk factor for breast

71 Mammographic density is an independent risk factor for b

72 In longitudinal studies, greater mammographic density is associated with an increased ris

73 Increased mammographic density is associated with increased breast

74 In this study, mammographic density is measured by using a fully automa

75 Mammographic density is one of the strongest predictors

76 Mammographic density is positively associated with plasm

77 In this study we examined whether mammographic density is related to blood telomere length

78 investigated whether the level of decline in mammographic density is related to breast cancer risk us

79 Mammographic density is strongly associated with breast

80 and estrogen-progestins is warranted because mammographic density may be a marker for risk for breast

81 Mammographic density (MD) is one of the strongest breast

82 ted 10-year breast cancer risk score (TCRS), mammographic density (MD), and a 77-single nucleotide po

83 colony organization, at the maximum level of mammographic density (MD), are investigated.

84 Increased mammographic density (MD), the proportion of dense tissu

85 n may be an important genetic determinant of mammographic density measure that predicts breast cancer

86 y variants were associated with at least one mammographic density measure.

87 Mammographic density measurements are associated with ri

88 Mammographic density measures adjusted for age and body

89 They had a total of 6,317 mammographic density measures available from the first 5

90 ociated with both breast cancer risk and the mammographic density measures.

91 aracteristics (n = 4,091), risk factors, and mammographic density (n = 1,957) were included.

92 Almost all increases in mammographic density occurred within the first year.

93 = 0.36) became positive after adjustment for mammographic density (odds ratio = 1.28, 95% confidence

94 Conclusion Mammographic density on FFDM images was positively assoc

95 omere length was not associated with percent mammographic density or dense area, before or after adju

96 (Beta coefficients express the increment in mammographic density per-unit increment (pg/ml) of each

97 ome-wide association studies (GWAS) of three mammographic density phenotypes: dense area, non-dense a

98 Percent mammographic density (PMD) adjusted for age and body mas

99 somatotype at age 18, benign breast disease, mammographic density, polygenic risk score, family histo

100 dentify etiologic pathways implicated in how mammographic density predicts breast cancer risk.

101 Mammographic density reflects the amount of stromal and

102 study suggests that absolute but not percent mammographic density reflects the lower breast cancer in

103 The authors determined whether mammographic density reflects these ethnic differences b

104 e clinical significance of the CEE effect on mammographic density remains to be determined.

105 However, mammographic density significantly modified the associat

106 spective data from the Early Determinants of Mammographic Density Study (n = 1,108; 1959-2008), we ex

107 st but statistically significant increase in mammographic density that is sustained over at least a 2

108 ciations between endogenous sex steroids and mammographic density, the authors conducted a 1998-2005

109 Percent mammographic density, the proportion of dense breast tis

110 udy, we show that epithelial cells from high mammographic density tissues have more DNA damage signal

111 onse compared with epithelial cells from low mammographic density tissues.

112 s seen in desmoplastic and disease-free high mammographic density tissues.

113 risk for developing cancer, especially high mammographic density tissues.

114 ome-wide association study (GWAS) of percent mammographic density to identify novel genetic loci asso

115 Among women in the highest tertile of mammographic density, total carotenoids were associated

116 use, and body mass index predict changes in mammographic density trends during adult life.

117 Interreader agreements for the mammographic density types and CT density grades were de

118 igher for the CT density grades than for the mammographic density types, with 0.79 (95% confidence in

119 tative descriptors for the physical finding, mammographic density, US characteristics in the area of

120 0, a single reader reassessed all images for mammographic density using Cumulus software (Sunnybrook

121 .6 years, the mean annual decline in percent mammographic density was 1.1% (standard deviation = 0.1)

122 Change in mammographic density was calculated as percentage change

123 Mammographic density was classified according to Breast

124 Mammographic density was estimated as the four-category

125 Mammographic density was measured by using a computer-as

126 Mammographic density was measured by using an automated

127 The ethnic difference in absolute mammographic density was particularly evident among wome

128 Mean age-adjusted percent mammographic density was significantly higher in Asian A

129 uctive factors, and family history, absolute mammographic density was statistically significantly low

130 Absolute and percent mammographic densities were determined with a previously

131 At 12 months, the odds of an increase in mammographic density were 13.1 (95% CI, 2.4 to 73.3) wit

132 s central), amount of FGT at MR imaging, and mammographic density were assessed on index images.

133 We examined whether age-related changes in mammographic density were different for 533 cases and 1,

134 ed breast cancer after adjusting for age and mammographic density were family history of breast cance

135 BPE pattern, MR imaging amount of FGT, and mammographic density were not significantly different be

136 val breast cancers in dense breasts (> 40.9% mammographic density) were less aggressive than interval

137 breast cancers in nondense breasts (</= 20% mammographic density) were significantly more likely to

138 changes have been associated with decreased mammographic density, which itself is strongly associate

139 tive would have a greater decline in percent mammographic density with age, compared with less physic

140 se results and to examine the association of mammographic density with age-related chronic disease an

141 The associations of mammographic density with breast cancer and the model fi