ライフサイエンスコーパス: manifest

1 umerous sensory and neuromuscular phenotypes manifest.

2 osis and treatment by detecting it before it manifests.

3 to understand how tissue-specific disease is manifested.

4 ncreased by 2 or more points in 90.1%; 86.7% manifested 2 or more SIRS criteria, and 54.4% had a qSOF

5 Overt hyperglycemia (>250 mg/dL) manifested 6 weeks after the start of glucocorticoid adm

6 We conclude that youth with IGT manifest a global decline in insulin sensitivity, includ

7 ur findings demonstrated that liver fibrosis manifested a beneficial role for host survival and apopt

8 Two AD subtypes manifested a CpG island methylator phenotype.

9 six individuals from four unrelated families manifesting a non-degenerative form of PCH.

10 repressive polycomb marking of genes, later manifesting abnormal DNA methylation by 10 months.

11 Unlike visual art, which is manifest across space, music is manifest across time.

12 rt, which is manifest across space, music is manifest across time.

13 Furthermore, IFIH1(T946) mice manifested an embryonic survival defect consistent with

14 udies of membrane proteins have successfully manifested an in-depth understanding of their biological

15 ) can be described as cautious and hesitant, manifesting an excessive indecisiveness that hinders eff

16 n the whole striatum, caudate and putamen in manifest and premanifest HDGECs compared with healthy co

17 ervoirs can generate a strong signal without manifesting any observable plasticity.

18 onless quantum anomalous Hall edge states it manifests are of particular interest for spintronics, as

19 MCPs manifest as a complex of insertions around a bacteriopha

20 incentive salience to reward cues, which can manifest as a propensity to approach and contact pavlovi

21 SJS/TEN mostly manifest as a reaction to new drug use, but little is kn

22 subtypes of HIV-associated vasculopathy may manifest as a result of an immune reconstitution-like sy

23 The optimal strategy would manifest as acuity loss, specifically in regions of fast

24 Kin discrimination can manifest as an apparent demarcation line (a region lacki

25 nge of autoimmune/dermatologic disorders can manifest as DG, although the two more common are oral li

26 t distinguishes one person from another, may manifest as diverse rearrangements of functional connect

27 These differences between studies can manifest as effect size heterogeneity.

28 in the water contained in the ocean and can manifest as global sea level variations.

29 for diagnosis of malignancy in lesions that manifest as microcalcifications at mammography.

30 ce among these AID orthologs is predicted to manifest as notable structural differences.

31 omic CAKUT) or cause renal diseases that may manifest as phenocopies of CAKUT.

32 By E18, these early patterning effects are manifest as profound changes in cell fates [short hair c

33 verse group of skeletal dysplasias and often manifest as short stature, growth-plate irregularities,

34 Such heterogeneity will manifest as variations in the depths at which melt becom

35 related to obliquity-paced solar radiation, manifest as variations in total summer energy.

36 However, the absence of TmeA manifested as a decrease in infectivity in both tissue c

37 rlying this was a striking molecular synergy manifested as a dramatically altered gene expression pro

38 f cleavage of the bifunctional marker, which manifested as a marked shift in the normalized YFP/mCher

39 the pancreas by gut-derived lymphocytes that manifested as a pancreatic insulitis with beta-islet cel

40 si-rhythmic intraseasonal oscillations (ISO) manifested as alternate 'active' phases of copious rainf

41 These processing deficits manifested as an increase in firing rate, a broadening o

42 jections caused systemic inflammation, which manifested as an increase in plasma pro-inflammatory cyt

43 The burden of atherosclerosis manifested as an increasing number of symptomatic vascul

44 n, impairing the iron absorption; clinically manifested as anemia of inflammation (AI).

45 differential regulation of CaMKII function, manifested as autoinhibition (pT305 phosphorylation) fol

46 in aspartate depletion that was specifically manifested as auxotrophy within PIK3CA mutant cells.

47 Congenital malformations can be manifested as combinations of phenotypes that co-occur m

48 Persistence, manifested as drug tolerance, represents a significant o

49 This effect manifested as increased survival following injection of

50 ureus conferred responsiveness to IL-20 that manifested as modification of actin polymerization and i

51 ve change in membrane phospholipid polarity, manifested as phosphatidylserine externalization, which

52 rdetella pertussis can cause severe disease, manifested as pronounced leukocytosis, pulmonary hyperte

53 leads to glomerular dysfunction, frequently manifested as proteinuria.

54 Neoplasia manifested as transplantable CD8+ lymphoma or leukemia,

55 , as well as associated immune dysregulation manifesting as autoimmunity or allergic inflammation.

56 ctomized 30-year-old patient with severe WAS manifesting as cutaneous vasculitis, inflammatory arthro

57 striatum, especially in the rostral caudate, manifesting as excess synthesis and release.

58 etal testes that appear between e19.5-e21.5, manifesting as focal aggregation of Leydig cells and ect

59 of the p53 pathway and DNA damage response, manifesting as gamma-H2A.X positivity in neurons of the

60 egnancy impose long-term detrimental effects manifesting as metabolic dysfunction in adult male offsp

61 In fisheries, the tragedy of the commons manifests as a competitive race to fish that compresses

62 action potential conduction velocity, which manifests as a progressive increase in response latency.

63 bodies are seen in the nucleus, and it often manifests as a severe phenotype.

64 Type 2 diabetes in adolescence manifests as a severe progressive form of diabetes that

65 n screen-diagnosed nonsmall cell lung cancer manifests as a subsolid nodule.

66 ge localization on the picosecond time scale manifests as a time-dependent Stark shift in the visible

67 sure' in collecting lymphatic vessels, which manifests as a transient drop in pressure downstream of

68 n in kidney function, which, histologically, manifests as crescent formation in most glomeruli.

69 , as does the degree to which incomplete XCI manifests as detectable sex differences in gene expressi

70 which holds that stressful in utero exposure manifests as disease in adulthood.

71 lar organ, impaired terminal differentiation manifests as immature stereocilia and kinocilia on the a

72 eased learning rate with generalization that manifests as immediate boosts to performance.

73 detect or else conflate generalization that manifests as increased learning rate with generalization

74 creased susceptibility at the cellular level manifests as increased susceptibility to typhoid fever i

75 Clinically, the condition manifests as parkinsonism with the addition of progressi

76 nt sound associated with very bright meteors manifests as popping, hissing, and faint rustling sounds

77 N) is a common complication of shingles that manifests as prolonged excruciating pain, which has prov

78 s concentrated at different locations, which manifests as rainbow guided waves.

79 oxicity that culminates in neuron injury and manifests as re-experiencing symptoms and other memory a

80 s an inherited and irreversible disease that manifests as retinitis pigmentosa (RP) and bilateral neu

81 the intensive care unit (ICU) most commonly manifests as sepsis, ventilator-associated pneumonia, an

82 remains debated how changes in excitability manifest at the behavioral level in perceptual tasks.

83 This chemical property is manifested at physiological concentrations between 5 and

84 Since genome alteration are manifested at the protein level, we integrated protein a

85 along particle track, with some discrepancy manifesting at track-end.

86 30% of individuals with SRNS whose symptoms manifest before 25 years of age.

87 , decreased cell viability, organelle damage manifest by mitochondrial depolarization, disordered aut

88 reduction in aerosol-radiation interactions, manifested by a latitudinal-dependent reduction of the a

89 Significant alleviation of liver damage manifested by a marked decrease in ALT, and AST serum le

90 a dramatic modulation of the band structure, manifested by a strain-driven indirect-to-direct bandgap

91 and functionally distinct modifications are manifested by adenylation prior to editing, and by post-

92 al units through a global cascading process, manifested by an abrupt first-order transition in dynami

93 dden decrease in glomerular filtration rate, manifested by an increase in serum creatinine concentrat

94 owed a systemic hyperinflammatory phenotype, manifested by an increased monocytic release of cytokine

95 ction of the antiapoptotic Bcl-2 proteins is manifested by capturing and neutralizing the proapoptoti

96 Unique shape-memory transitions manifested by directional extension and subsequent retra

97 ibited a decrease in oncogenic signaling, as manifested by downregulation of the transcription factor

98 ent irregularities, marked arrhythmogenicity manifested by early afterdepolarizations and triggered a

99 ry response of the encountering macrophages, manifested by elevation in mRNA expression of Tnfalpha a

100 vere injury includes type 2 immune responses manifested by elevations in interleukin (IL) 4, IL5, and

101 ing process of further biological remodeling manifested by further reduction in RVESVi.

102 exhibit peripheral immune activation that is manifested by higher numbers of granulocytes, plasmablas

103 The devices' robustness is manifested by its retained excellent performance and una

104 revealed due to hexapeptide association, as manifested by lowering of transient interactions between

105 (>0.90) is observed for each dyad, which is manifested by nearly exclusive emission from bacteriochl

106 The charge density wave order is manifested by periodic distortions of the one-dimensiona

107 n causes defects in synaptic transmission as manifested by reduced amplitude of both evoked and minia

108 ne responses against C. rodentium infection, manifested by reduced crypt hyperplasia, reduced epithel

109 NASH was ameliorated in the M+G49 group, manifested by reduced inflammation, steatosis, oxidative

110 enomic disorders are the clinical conditions manifested by submicroscopic genomic rearrangements incl

111 ons of signaling kinases in cancer cells are manifested by the downstream effectors of cytoplasmic si

112 ng amelioration of the dystrophic phenotype, manifested by the prevention of fibrosis and restoration

113 e variant conferred gain of function to UBF, manifesting by markedly increased UBF binding to the rDN

114 ven after excluding patients with clinically manifest cardiac disease.

115 f subclinical cardiac disease and clinically manifest cardiac diseases were associated with CMIs on 3

116 f subclinical cardiac disease and clinically manifest cardiac diseases with CMIs graded on 3-T MRI in

117 Vertebrate hearing organs manifest cellular asymmetries across the radial axis tha

118 trongly associated with the development of a manifest central nervous system (CNS) synucleinopathy (o

119 or phenotype, exhibit reduced viability, and manifest characteristics of anergy.

120 amolecular systems is intensively pursued to manifest chirality in a wide range of applications rangi

121 illary plexuses in diabetic eyes that do not manifest clinical retinopathy.

122 ic mechanism for human vascular disease that manifests clinical complications in sickle cell disease

123 em, and pericardium, which may take years to manifest clinically.

124 ure are at high risk of phenoconverting to a manifest CNS synucleinopathy.

125 rmal appearance, self-renewal and growth but manifest defects upon differentiation.

126 Interestingly, TH-Cre;ErbB4(f/f) mice manifest deficits in learning, spatial and working memor

127 PET data from 58 patients with incipient and manifest dementia due to AD were analyzed.

128 Critically ill patients have manifest diaphragm muscle fiber atrophy and weakness in

129 disorders; however, abnormalities appear to manifest differently.

130 s of its Origami building blocks, and others manifesting due to its unique geometrical construction a

131 ion indicates that PdcA-dependent phenotypes manifest during stationary phase, consistent with regula

132 ncies occur with a higher incidence rate and manifest earlier in life in patients with primary immuno

133 patients with EI and increased fatigability manifest early, rapid exercise-induced declines in SM hi

134 gical features are also present in AD, often manifesting early in the course of the disease before th

135 luding a higher proportion of WGD duplicates manifesting expression alteration, and differential prop

136 ipt can examine an Illumina genotyping array manifest file and can detect all problematic SNPs, inclu

137 This phenotype manifested further with extramedullary tumors, hepatic m

138 om 1538 eyes of 909 subjects with suspect or manifest glaucoma and >/=5 VF examinations.

139 , meaning that tumors that become clinically manifest have managed to subvert or hide from immunosurv

140 d for the study, 37 ambulatory patients with manifest HD (mean [SD] age, 52.4 [11.5] years; 22 [59%]

141 triatal molecular changes in premanifest and manifest Huntington's disease (HD) gene expansion carrie

142 and manifested If-dependent automaticity.

143 E2f1 (-/-) mice manifest impaired GC responses, which is rescued by rest

144 q11DS participants were still more likely to manifest impaired stress tolerance, avolition, and ideat

145 .5%) of NPDR and 28 (70.0%) of PDR eyes that manifested improvement at 1 year maintained improvement

146 perceptual outcomes (phosphenes), which were manifest in both early and late patterns of evoked activ

147 d to determine how the observed associations manifest in childhood.

148 pathways and pathological processes that can manifest in circulation as biomarkers.

149 Coulomb correlations can manifest in exotic properties in solids, but how these p

150 ve diseases, but also that tau pathology can manifest in healthy neural tissue transplanted into the

151 cer and activator of transcription 1 (STAT1) manifest in immunodeficiency and autoimmunity with impai

152 drome protein (WASp) expression or activity, manifest in immunodeficiency, autoimmunity, genomic inst

153 ssion, contributing to a state of exhaustion manifest in impaired proliferation and cytokine producti

154 de (NO) dysregulation and that this would be manifest in increased myocardial S-nitrosylation, a post

155 ic or chondrogenic progenitor cells does not manifest in midline defects.

156 arkinson's disease classically first becomes manifest in one hemibody before affecting both sides, su

157 ment, since any effects of mixture should be manifest in one or both of these traits.

158 FeNx C active sites in the carbon framework manifest in superior catalytic activity toward oxygen re

159 How does SES manifest in the brain, and how do its neural correlates

160 ived from the Apo-CII protein and appears to manifest in the elderly and preferentially affect the ki

161 s the spectrum of liver pathologies that can manifest in the first 6 months of life and is intended t

162 nic, and spin phenomena at atomic scales can manifest in their collective properties.

163 r nature of these materials is unequivocally manifested in a few recent studies such as intercluster

164 Clinically, SPG5 manifested in childhood or adolescence (median 13 years)

165 rvices to increasing the value of imaging as manifested in clinical outcomes, patient satisfaction, a

166 deficiency causes a primary immunodeficiency manifested in extreme susceptibility to common respirato

167 eceptors exhibit high temporal resolution as manifested in frequency response to oscillating light of

168 dence that such social category coactivation manifested in neural patterns of the right fusiform cort

169 importance, key features of this pathway are manifested in patients with TNBC and in The Cancer Genom

170 eading and initiated intracellular signaling manifested in phosphorylation of Erk1/2.

171 th distinct developmental potentials, can be manifested in sibling cell size asymmetry.

172 he first time that bursty and quiet seasons, manifested in surface magnetic structures, can be caused

173 es above 14 K, and phonon backscattering, as manifested in the classical size effect, is responsible

174 egree of the carrier lifetime separation, as manifested in the distinctly different temperature depen

175 yz)N(px,y) pi*-orbitals, a splitting that is manifested in the electronic absorption spectrum of 1 (l

176 How inter-individual variations are manifested in the functional brain networks was examined

177 c, 8.0 dpc and 10.5 dpc, the tetraploid ESCs manifested in the same location as the diploid ESCs.

178 pi-Conjugation is manifested in these COFs in significantly reduced band g

179 ively low surface-to-volume ratio, which was manifested in this work through the enhanced conductance

180 Epilepsy is a common neurological disease, manifested in unprovoked recurrent seizures.

181 chronic myeloid leukemia (CML)-like disease manifesting in "lymphoid blast crisis." The biological h

182 mounts of each cell line had lower precision manifesting in higher standard deviations.

183 Hematopoietic defects start manifesting in late gestation at E17.5.

184 We demonstrate that disease manifests in both heterozygotes and homozygotes, indicat

185 rather than the actual sequencing data which manifests in high recurrence of regions that can/cannot

186 SD) is a behaviorally defined condition that manifests in infancy or early childhood as deficits in c

187 en scrutinized for decades, including how it manifests in optical properties.

188 rease in 5f orbital energy across the series manifests in orbital-mixing and, hence, covalency driven

189 This effect manifests in otherwise healthy individuals who are at in

190 invariant orientation tuning of single units manifests in population response functions that broaden

191 e Hypothesis posits that herbivore migration manifests in response to waves of spring green-up (i.e.

192 where CBP interacts with eRNAs, stimulation manifests in RNA-dependent changes in the histone acetyl

193 on affinity for target versus non-target DNA manifests in specificity increasing then diminishing wit

194 ingle neurons, how such adaptive versatility manifests in the collective population dynamics and func

195 w heterogeneity at the transcriptional level manifests in the physiologic profile of individual cells

196 Diabetic D2 mice manifested increased mitochondrial DNA lesions (8-oxogua

197 role of TmeA during chlamydial invasion that manifests independently of effects on AHNAK.

198 direct effects of climate from effects that manifest indirectly through species turnover across clim

199 ressures acting on virus subtypes, which can manifest into landscape-level effects.

200 , minor changes in the hydrophobic block are manifested into tremendous changes in the stability of t

201 of posthypoxic leukoencephalopathy that can manifest itself 1-2 weeks after the initial insult.

202 the fusion of two heavy-quark baryons might manifest itself.

203 esponse-gain function, whereas consciousness manifests itself as a contrast-gain function.

204 Second, attention manifests itself as a response-gain function, whereas co

205 This manifests itself as subtle but pervasive high-order epis

206 It manifests itself as white matter signal abnormalities wi

207 ss field"-is considered, this power law tail manifests itself by highly localized spots, which are si

208 tic length scale of approximately 20 nm, and manifests itself clearly when mechanical stress is appli

209 their preferences, but how exactly this bias manifests itself in learning and decision-making is uncl

210 rrangement within the system-a behavior that manifests itself in the oscillating MR.

211 ies with the motor context, a mechanism that manifests itself in the phase-locked entrainment of the

212 In magnetism, the topology of spin order manifests itself in the topological winding number which

213 rt and explain an ice removal mechanism that manifests itself simultaneously with freezing, driving g

214 The presence of such fields manifests itself through the hysteretic behavior of plan

215 Peptide dosing in cells manifests KDM4A target stabilization.

216 or congenital motor nystagmus in 22 (31.0%), manifest latent nystagmus or latent nystagmus in 17 (24.

217 entation of a spectrum of disease that could manifest later in life, from mild dysfunction to severe

218 ing axonal peripheral neuropathy-and usually manifest later in life.

219 cephalopathy, hepatic, and renal dysfunction manifested later than cardiovascular and respiratory dys

220 nd brainstem, individuals with NF2 typically manifest low-grade tumors affecting the cranial nerves (

221 perior to that of dimeric TRAIL-Fc, but also manifests more favorable pharmacokinetic and antitumor p

222 Since adult OSA manifests MRI evidence of brain injury, and animal model

223 , hs-cTnT) in individuals with no clinically manifest myocardial injury.

224 of 63 PET studies in premanifest (n=158) and manifest (n=191) HDGECs and HCs (n=333) were included in

225 s with deletions and duplications of 15q13.3 manifest neuropsychiatric disease and cognitive deficits

226 ly, the retinal vessels in Apoa1bp(-/-) mice manifested normal pericyte coverage and vascular integri

227 own synergism between metals and warming was manifested not only during the larval stage but also aft

228 The user provides BDSS with a manifest of datasets stored in a remote storage reposito

229 de exposure, typically took several hours to manifest on the protein level.

230 arance of the first clinical symptoms, which manifest only after extensive propagation, opening novel

231 urring in otherwise healthy patients who may manifest other macular disease including AMD and myopic

232 atients were investigated, some of whom also manifested other features, including ichthyosis, primary

233 The women with PMDD manifested ovarian steroid-triggered behavioral sensitiv

234 LRRK2 mutation carriers with manifest Parkinson's disease (n=15) had reduced striatal

235 LRRK2 mutation carriers without manifest Parkinson's disease (n=25) had greater (18)F-FD

236 ilar fashion in LRRK2 mutation carriers with manifest Parkinson's disease and individuals with sporad

237 disease, but LRRK2 mutation carriers without manifest Parkinson's disease show increased serotonin tr

238 uded LRRK2 mutation carriers with or without manifest Parkinson's disease, people with sporadic Parki

239 Twenty-five (37%) patients manifested PD on therapy: 17 with Richter transformation

240 to investigate whether Chrna7 deficient mice manifest phenotypes related to those seen in human indiv

241 hic analysis confirms that while CIP and CIT manifest planar structures, DPT shows a curved pi-conjug

242 clear gene, TK2, cause TK2 deficiency, which manifests predominantly in children as myopathy with mtD

243 Black-swan events manifest primarily as population die-offs and crashes (8

244 dentified longitudinal bacterial series that manifested progressive changes in liquid media growth, m

245 These systems manifest properties of the core, of the ligand shell, as

246 The idea that dominant primates manifest protocontempt to subordinates suggests that "lo

247 gender, race, preoperative and postoperative manifest refraction spherical equivalent (MRSE), preoper

248 t spectacle-corrected visual acuity (BSCVA), manifest refraction, and endothelial cell density (ECD).

249 toperative examination at 3 months including manifest refraction; uncorrected visual acuity (UCVA) an

250 le metal cocatalysts in the catalytic system manifest remarkable performance for deoxygenative reduct

251 ification of brucine at physiological pH 7.2 manifests remarkable performance at the developed biosen

252 CCRT is reliable in LAHNSCC except for late manifesting residual disease, which may require an addit

253 In contrast, early visual areas generally manifest responses to individual stimuli and to their in

254 prognosis, as many of these patients did not manifest restricted joint movements at the post-acute ph

255 ntrast administration; notably, some lesions manifested restricted diffusion on DWI images.

256 Significantly, FRCs of human lymphoid organs manifest similar COX-2/PGE2 hyperactivity and T cell sup

257 nsient effect was found to be ubiquitous and manifested similarly across objective and subjective mea

258 ed on the lower back, but some patients only manifest small collagenomas or have lesions elsewhere on

259 f the minimum angle of resolution [logMAR]), manifest spherical equivalent refraction (D), central co

260 The manifest spherical equivalent refraction changed on aver

261 electivity to the category of visual images, manifested stable "iconic" dynamics.

262 Bleeding was rare at presentation (5%) and manifested subsequently in fewer than 50%.

263 with trr alleles encoding catalytic mutants manifest subtle developmental abnormalities when subject

264 CD8(+) T-cell responses, liver disease often manifests systemically as immunoglobulin (Ig)-related sy

265 ion of cardiomyocytes many days before cells manifest the differentiated phenotype.

266 However, GAS CpsY does not manifest the in vitro phenotypes of its homologs in othe

267 Although Arf(M45A) mice manifest the latter defects, smArf alone remarkably resc

268 we identified numerous genetic variants that manifested their regulatory effects exclusively on immun

269 These conditions manifest themselves as physiological defects in specific

270 called bound states in the continuum (BICs), manifest themselves as resonances that do not decay.

271 , and how the generated triplet Cooper pairs manifest themselves in the self-consistently computed de

272 different classes of nonlinear wave systems, manifesting themselves as a localized temporal structure

273 his disease remains a challenge, as seizures manifest through mechanisms and features that span spati

274 iscovery of a memory effect in both systems, manifested through an increase of resistance at a specif

275 Human body responses are manifested through multiple, interacting modalities - th

276 Interestingly, stabilization was manifested through the same acceptor molecular orbital i

277 ails to support the needed inhibition, which manifests through reduced grey matter volumes, this regi

278 The antiferromagnetic long-range order manifests through the divergence of the correlation leng

279 ptimal path to move each of the files in the manifest to the site of workflow execution.

280 The P2Ns manifest transferrin receptor (TfR) colocalization in ex

281 sing parturition-inducing hormone receptors, manifesting type 1 immunity, and most unexpectedly, gene

282 As a consequence, RDEB individuals manifest unremitting skin blistering that evolves into c

283 We now show that this effect of T2S is also manifest upon infection of human THP-1 macrophages and p

284 imulants, the in vivo chemical complexity it manifests upon ingestion has impeded efforts to unambigu

285 dividuals aged between 2.1 and 13 years, who manifest variable degrees of developmental delay/intelle

286 ation, infection, and structural lung damage manifest very early in life and are prevalent among pres

287 ility, stability, and antibiofilm properties manifested when converted into bioactive materials, asse

288 Type 1 diabetes (T1D) manifests when the insulin-producing pancreatic beta cel

289 exmedetomidine-induced altered arousal would manifest with reduced functional connectivity between th

290 generalized myopathy; only 12 patients (71%) manifested with sideroblastic anemia.

291 urologic disorders, including gangliosidoses manifesting with neurodegeneration and neuroinflammation

292 iosynthesis, lead to GNE myopathy, a disease manifesting with progressive muscle atrophy and weakness

293 rmolysis bullosa is a heritable skin disease manifesting with sub-lamina densa blistering, erosions,

294 li syndrome (PWS) is a complex disorder that manifests with an array of phenotypes, such as hypotonia

295 Botulism manifests with cranial nerve palsies and flaccid paralys

296 In contrast to antenatal BS, classic BS manifests with highly variable phenotypes.

297 eage kinase domain-like (MLKL) and generally manifests with morphological features of necrosis.

298 Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.

299 e (FPIES) is a non-IgE-mediated food allergy manifesting within 1 to 4 hours of food ingestion with r

300 CAKUT causes approximately 40% of ESRD that manifests within the first three decades of life.