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1 Furthermore, parainflammatory neutrophils manifest as 2 distinct subpopulations-based on size, gra
3 theless contributing to severe PC depletion, manifest as a characteristic supratherapeutic INR caused
4 with rapid neurological decline (Type II) or manifest as a chronic form (Type III) with a wide spectr
6 in atherosclerotic plaques, but it can also manifest as a hereditary disorder caused by mutations of
7 This voltage-current phase relation would manifest as a kinetic inductance, representing the reluc
8 ose that affect the nervous system generally manifest as a profound deterioration in neurologic funct
9 incentive salience to reward cues, which can manifest as a propensity to approach and contact pavlovi
10 GAS), is a human bacterial pathogen that can manifest as a range of diseases from pharyngitis and imp
12 subtypes of HIV-associated vasculopathy may manifest as a result of an immune reconstitution-like sy
15 vealed upon competition or by system stress, manifest as a strikingly heightened susceptibility to pr
16 , raising the issue of why certain mutations manifest as a systemic disorder whereas other changes in
18 yramidal neurons show increased excitability manifested as a decreased medium afterhyperpolarization
20 rlying this was a striking molecular synergy manifested as a dramatically altered gene expression pro
21 se exhibited a high GATA3/T-bet ratio, which manifested as a high IL-4/IFN-gamma ratio in respiratory
22 f cleavage of the bifunctional marker, which manifested as a marked shift in the normalized YFP/mCher
23 e effective for treating variant angina that manifested as a non-respiratory tract symptom of aspirin
24 the pancreas by gut-derived lymphocytes that manifested as a pancreatic insulitis with beta-islet cel
26 it slowed and reduced viral gene expression, manifested as a shift in mean latent time from 4 to 6 h
27 d consent was obtained, 50 lung cancers that manifested as a solid nodule on computed tomographic (CT
30 frequent post-transcriptional modifications, manifested as A-to-G mismatches when comparing RNA seque
31 o a series of sequential sodiation reactions manifesting as a cascade of processes observed in the el
32 cleotide polymorphism (SNP)-specific manner, manifesting as a post-transcriptional control of express
33 be chronically infected with M. amphoriforme manifesting as a relapsing-remitting bacterial load, int
34 teraction in right dorsolateral PFC (DLPFC), manifesting as a relative activation increase in healthy
35 r mitochondrial energy production frequently manifests as a cardiomyopathic phenotype, underscoring t
37 the spine pathology of schizophrenia, which manifests as a decrease in the number of dendritic spine
38 Autism is a neurodevelopmental disorder that manifests as a heterogeneous set of social, cognitive, m
39 d-type (WT) huntingtin (Htt), as HD commonly manifests as a heterozygous condition in humans, and los
42 Although this bias in perceived identity manifests as a misperception, it is adaptive: visual pro
45 action potential conduction velocity, which manifests as a progressive increase in response latency.
46 taneus maximus [mouse]) reflex (CTMR), which manifests as a puckering of the dorsal thoracolumbar ski
47 causes rapid degradation of SLC25A46, which manifests as a rare disease, pontocerebellar hypoplasia.
48 Esophageal motility disturbance classically manifests as a reduced lower esophageal sphincter pressu
52 local change in dynamic contact angles which manifests as a smooth and continuous motion of the CL.
55 ge localization on the picosecond time scale manifests as a time-dependent Stark shift in the visible
56 sure' in collecting lymphatic vessels, which manifests as a transient drop in pressure downstream of
58 ice showed developmental irregularities that manifested as adult-onset glomerulosclerosis and protein
60 EGABA) and increased intrinsic excitability (manifest as altered spike initiation properties) were ne
61 the genetic liability for schizophrenia that manifests as altered reconfiguration of brain networks d
62 si-rhythmic intraseasonal oscillations (ISO) manifested as alternate 'active' phases of copious rainf
66 r, when compared with patients whose relapse manifested as an increase in FLC both alone and with a w
67 jections caused systemic inflammation, which manifested as an increase in plasma pro-inflammatory cyt
69 s display suppressed immune functions, often manifested as an increased susceptibility to secondary i
71 isrupted for several minutes but homeostasis manifested as an overall elevation of the time spent in
72 re delayed reactive hyperemia response time, manifesting as an increase in time to peak perfusion in
73 a highly significant effect of NRG3 genotype manifesting as an unanticipated increase in ventrolatera
75 cate multi-electron-conversion reactions and manifests as an effective and efficient strategy to enha
79 genetic risk for schizophrenia appears to be manifest as anxiety and negative symptoms during adolesc
81 .5 cells infected with the JFH-1 HCV strain, manifesting as apoptosis highly correlated with growth a
84 e the preferential orientation of PSI, which manifest as asymmetry in tunneling charge-transport.
85 y anthracycline-induced cardiotoxicity (ACT) manifesting as asymptomatic cardiac dysfunction and cong
88 , as well as associated immune dysregulation manifesting as autoimmunity or allergic inflammation.
89 iency (CVID) experience immune dysregulation manifesting as autoimmunity, lymphoproliferation, and or
90 differential regulation of CaMKII function, manifested as autoinhibition (pT305 phosphorylation) fol
91 in aspartate depletion that was specifically manifested as auxotrophy within PIK3CA mutant cells.
92 patterns, with the most substantial impacts manifested as avoidance of well pads with active drillin
93 well as N-Calpha backbone bonds, accordingly manifested as b/y, a, and c/z fragment ion series in tan
95 sult in tissue-level control mechanisms that manifest as biological oscillators, such as observed in
96 hout asplenia; P < .001) and more frequently manifested as bloodstream infection (31% vs 6%; P = .002
97 ibility to incomplete isotope incorporation, manifesting as broadening of labeled intact protein peak
99 ers found at screening mammography, 38 (88%) manifested as calcifications and 28 (65%) were ductal ca
100 C4d-negative antibody-mediated rejection manifesting as capillaritis (g>/=1 and ptc>/=1) with det
101 he index family, presentation was milder and manifested as cardiac fibrosis and an exquisite sensitiv
102 ession of genes is inherently stochastic and manifests as cell-to-cell variability or noise in protei
103 the observed data, since energy flow may be manifested as changes in both structure and dynamics.
104 hieve changes in protein folding, which were manifested as changes in the number of labile protons ex
105 ow obstruction is established early in life, manifests as childhood asthma and wheezy bronchitis, and
106 is initiated on the mRNA cleavage-level, yet manifested as chromatin-level silencing that in plants i
110 as tauopathies, in which clinical phenotypes manifest as cognitive impairment, behavioral disturbance
112 is heterogeneity, when compatible with life, manifests as constitutional mosaicism, chimerism, and mi
115 ctomized 30-year-old patient with severe WAS manifesting as cutaneous vasculitis, inflammatory arthro
116 We have previously identified anhedonia, manifest as decreased sucrose preference and social play
117 abnormality of retina/optic nerve function, manifested as decreased contrast sensitivity (in the abs
118 e of optic nerve or retinal dysfunction that manifests as decreased contrast sensitivity, even with g
119 e that, as in humans, normal aging primarily manifests as defects in relaxation (diastole) while pres
121 , as does the degree to which incomplete XCI manifests as detectable sex differences in gene expressi
122 ty to TMP/UVA relative to wild-type animals, manifested as developmental arrest, defects in adult tis
123 shold, effects of multiple scattering become manifest as deviations from the underlying binary p-wave
124 nge of autoimmune/dermatologic disorders can manifest as DG, although the two more common are oral li
125 nsulin resistance in mice typically does not manifest as diabetes due to multiple compensatory mechan
128 This causes sex-specific differences that manifest as differential gene expression and associated
133 ted in polysialyltransferase-deficient mice, manifesting as disturbed lymph node homeostasis and unre
134 t distinguishes one person from another, may manifest as diverse rearrangements of functional connect
135 Modulation of interactions among neurons can manifest as dramatic changes in the state of population
137 diabetes experience chronic allostatic load, manifest as dynamic disturbances in reactivity to and re
138 including major depression and schizophrenia manifest as dysfunction of the GABAergic system within t
140 genital-onset disorder of connective tissue, manifesting as early-onset joint hypermobility, joint co
141 netic burden arising from human mutant LRRK2 manifests as early pathophysiological changes to dopamin
143 hilic enzyme, although these differences may manifest as either increased or decreased relative flexi
144 en accompanied by a pleiotropic fitness cost manifested as either a reduced growth rate or enhanced i
145 common symptom in Parkinson's disease, which manifests as either a consistent or progressive reductio
147 infections, chronic Q fever develops, mostly manifesting as endocarditis, infected aneurysms, or infe
148 fection with Brucella spp, and most commonly manifests as endocarditis, peripheral and cerebrovascula
150 ) is a fundamental feature of asthma that is manifest as exercise-induced bronchoconstriction (EIB).
154 etal testes that appear between e19.5-e21.5, manifesting as focal aggregation of Leydig cells and ect
156 A sequencing, quantitative trait loci (QTLs) manifest as fragment count differences between individua
157 of the p53 pathway and DNA damage response, manifesting as gamma-H2A.X positivity in neurons of the
158 ts: local dissociation of adherens junctions manifested as gaps in vascular endothelial (VE)-cadherin
159 ype data, however, is difficult because both manifest as genetic similarity through the sharing of al
161 ic effects from paclitaxel with trastuzumab, manifesting as grade 3 or 4 LVSD or asymptomatic LVEF de
163 stress- or CRF-induced sensitization of BLA manifested as heightened startle and PPI deficits in res
164 mutagenesis and genotoxicity, which usually manifest as hematopoietic malignancy, represent major ba
165 on of lipid droplets in infected hepatocytes manifests as hepatosteatosis, a common pathology observe
166 nges associated with domestication may first manifest as heritable changes to global patterns of gene
168 ments resulted in enhanced response control, manifest as highly specific effects in the ability to ca
169 ilure (POF) is genetically heterogeneous and manifests as hypergonadotropic hypogonadism either as pa
171 lar organ, impaired terminal differentiation manifests as immature stereocilia and kinocilia on the a
175 icant plasticity in the sensorimotor cortex, manifested as improved discriminability of movement info
176 ommon feature of neuropsychiatric disorders, manifesting as impulsivity for anticipated incentives.
177 ure of posttraumatic stress disorder (PTSD), manifests as inappropriate, uncontrollable expression of
178 n have nontargeted heterologous effects that manifest as increased protection against nonvaccine infe
179 anges in actin polymerization are physically manifested as increased cellular stiffness, and leads to
181 milar degree of mid-cycle immune activation, manifested as increased expression of cytokines and lyti
182 Cs is associated with their destabilization, manifested as increased protease and nuclease sensitivit
184 t greater Nrf2 activity than Ier3(+/+) mice, manifesting as increased nuclear Nrf2 protein level and
185 detect or else conflate generalization that manifests as increased learning rate with generalization
186 creased susceptibility at the cellular level manifests as increased susceptibility to typhoid fever i
187 At the cellular level, this reorganization manifests as increased width of vimentin fibers and the
188 t of mGluR5 activation is to produce anxiety manifested as indiscriminate fear of both tone and conte
189 to inefficient caspase-dependent apoptosis, manifested as inefficient nuclear lamin degradation in t
190 Thus, primary infection in adolescence can manifest as infectious mononucleosis (IM), as a fatal il
193 e (KBD) is a chronic osteoarthropathy, which manifests as joint deformities and growth retardation.
195 interaction with the allosteric binding site manifests as low-affinity binding of methoctramine at th
196 it dysregulated homeostatic expansion, which manifests as lymphoproliferative disease with autoantibo
197 in her 50s with a history of AL amyloidosis manifesting as macroglossia and bilateral carpal tunnel
198 ercentage (89%, 99 of 111) of breast cancers manifesting as masses and microcalcification clusters, w
200 egnancy impose long-term detrimental effects manifesting as metabolic dysfunction in adult male offsp
203 ection (CDI) caused by toxins A and/or B can manifest as mild diarrhea to life-threatening pseudomemb
205 ureus conferred responsiveness to IL-20 that manifested as modification of actin polymerization and i
206 ly, breakdown of medial immunoprivilege that manifests as more intense leukocytic infiltrates, loss o
209 e antenna-coupled blackbody radiation, which manifests as narrow spectral emission peaks in the mid-i
210 s of these cat-ANF spontaneous spike trains, manifest as negative serial ISI correlations and reduced
213 ncement and the unpredicted prediction error manifested as neuronal attenuation on the N1 event-relat
214 d stimuli, the mispredicted prediction error manifested as neuronal enhancement and the unpredicted p
218 ng for lung cancer, all cases of lung cancer manifesting as NSN in the National Lung Screening Trial
219 lends further support that lung cancers that manifest as NSNs have an indolent course and can be mana
221 ormal cortical response to flickering light, manifesting as particular electroencephalographic change
223 advantage during chronic cystitis, which is manifested as persistent bacteriuria, high bladder bacte
224 striking predilection for chronic cystitis, manifesting as persistent bacteriuria, high-titer bladde
227 ve change in membrane phospholipid polarity, manifested as phosphatidylserine externalization, which
228 ersity among EV-D68 isolates in Kansas City, manifest as phylogenetically distinct lineages, indicati
230 nt sound associated with very bright meteors manifests as popping, hissing, and faint rustling sounds
231 lymphoproliferative disorders of these cells manifesting as primary effusion lymphoma (PEL) and multi
233 By E18, these early patterning effects are manifest as profound changes in cell fates [short hair c
234 r infection in IFN-alphabetagammaR(-/-) mice manifested as profoundly elevated aspartate transaminase
235 ly occur as a result of immunocompromise and manifest as progressive multifocal leukoencephalopathy (
237 N) is a common complication of shingles that manifests as prolonged excruciating pain, which has prov
238 rdetella pertussis can cause severe disease, manifested as pronounced leukocytosis, pulmonary hyperte
241 ncidence of recurrent venous thromboembolism manifested as pulmonary embolism or deep vein thrombosis
244 ted firing of these dopaminergic neurons can manifest as rapid and robust fluctuations in striatal do
245 oxicity that culminates in neuron injury and manifests as re-experiencing symptoms and other memory a
247 ioedema (HAE) due to C1 inhibitor deficiency manifests as recurrent swelling attacks that can be disa
248 nths, had significant cutaneous disease that manifested as red violaceous plaques of the cheeks, nose
249 el-dependent activity via real-time fMRI and manifested as reduced amygdala reactivity to visual stim
250 within the skin-draining lymph nodes (sdLN), manifested as reduced CD4+ cell proliferation and cytoki
251 CE is associated with greater LV dysfunction manifested as reduced circumferential shortening, reduce
252 ffer late effects of poorer postural control manifested as reduced contribution of vision and as redu
255 ith mucosal immune system dysfunction, which manifests as renal IgA deposition that leads to impairme
257 cal dystonia is a neurological disorder that manifests as repetitive involuntary spasms and/or aberra
258 opic component of the chemical shift tensor, manifested as residual chemical shift anisotropy (RCSA).
259 s an inherited and irreversible disease that manifests as retinitis pigmentosa (RP) and bilateral neu
260 ' decisions, these choices can be swayed and manifest as riskier or safer behavior than one would exp
261 BMT) and is characterized by tissue fibrosis manifesting as scleroderma and bronchiolitis obliterans.
262 ations, it may be at subclinical levels, may manifest as scrapie, or may be masked by coinfection wit
263 the intensive care unit (ICU) most commonly manifests as sepsis, ventilator-associated pneumonia, an
264 eads to a proinflammatory condition that can manifest as septic shock, multiple organ failure, and de
266 hereditary disease of heme biosynthesis that manifests as severe photosensitivity and hepatotoxicity.
268 verse group of skeletal dysplasias and often manifest as short stature, growth-plate irregularities,
269 gestive loci (4,208 of 15,930, P < 10(-100)) manifest as significant methylation quantitative trait l
271 -stage waves mediated by acetylcholine (ACh) manifest as slow, spreading bursts of action potentials.
277 regardless of the adult vitamin A status and manifested as structural changes in the bronchial SM and
279 cross-modal reorganization that functionally manifests as superior visual motion detection ability in
280 th a primary immunodeficiency, predominantly manifesting as susceptibility to Epstein-Barr virus (EBV
281 c imaging can detect functional differences (manifesting as temperature reductions) in the tumour res
282 In the spectral domain, nonlinear dynamics manifest as the development of a chain of harmonics stat
283 The degradation of locomotor pattern is manifest as the loss of interjoint coordination and alte
284 mRNA localization to the ER-bound polysomes manifested as the earliest event, which is followed by A
285 anism for priming naive B cell responses and manifested as the induction of SA-dependent pan-activati
286 r system of coupled microresonators, EPs are manifested as the loss-induced suppression and revival o
288 organization of the axolemma both radially, manifested as the mesaxonal line, and longitudinally, de
289 erative disease, adrenoleukodystrophy, which manifests as the spinal cord axonopathy adrenomyeloneuro
292 lopment, disruptions in motor behaviors that manifest as unproductive swim attempts, and spontaneous,
293 iency is a rare autosomal recessive disorder manifesting as urolithiasis or crystalline nephropathy.
298 ng-associated ependymal-cell pathologies can manifest as ventricular gliosis, ventricle enlargement,
299 subclavian steal").Subclavian steal may also manifest as vertebrobasilar insufficiency or,most common
300 d suggest that the presence of cerebral SVD, manifested as WMH, is associated with posterior brain hy
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