ライフサイエンスコーパス: manifestation

1 on to corticosteroid-refractory neutrophilic manifestation.

2 ving initial cognitive deficits and clinical manifestation.

3 logical changes long before any pathological manifestation.

4 s, year and organ transplanted, and clinical manifestation.

5 tary disorders for which stroke is a primary manifestation.

6 estinal mucosal immunity upstream of disease manifestation.

7 eceptors play a critical role in the disease manifestation.

8 linical course over the first week after AKI manifestation.

9 on is known to be associated with skin aging manifestations.

10 al numbers and exhibited no overt autoimmune manifestations.

11 nerally severe phenotype, including nonmotor manifestations.

12 , of which 64.7% presented clinical bleeding manifestations.

13 rough which THC exposure elicits psychiatric manifestations.

14 oral effects of cannabis related psychiatric manifestations.

15 injection partially rescued these phenotypic manifestations.

16 various contributing mechanisms and clinical manifestations.

17 oncomitantly promoting aberrant IgG mediated manifestations.

18 tant mosaicism commonly ameliorated clinical manifestations.

19 ding insight into their disparate phenotypic manifestations.

20 heterozygotes had less severe or no clinical manifestations.

21 inal copper homeostasis or to Wilson disease manifestations.

22 ay produce severe neurologic and hematologic manifestations.

23 e years after complete resolution of initial manifestations.

24 ive and asymptomatic) chronic Chagas disease manifestations.

25 ents and is strongly associated with disease manifestations.

26 dlBST could play a role in LID hyperkinetic manifestations.

27 stinal disorders, as well as extraintestinal manifestations.

28 All patients had bilateral ophthalmic manifestations.

29 up of disease course in relation to clinical manifestations.

30 or XLH should target both systemic and local manifestations.

31 with pain or peripheral nervous system (PNS) manifestations, 39% were LGI1-IgG seropositive (7% had s

32 atremic encephalopathy exhibiting neurologic manifestations, a bolus of 100 mL of 3% saline, given ov

33 are associated with more pronounced disease manifestations, adverse mutation profile, and worse outc

34 Similar inflammatory manifestations also exist in patients with STING-associa

35 We compared the prevalence of ocular manifestations among reported syphilis cases by demograp

36 MA) have an increased risk of other allergic manifestations (AMs).

37 However, whether SHS exposure affects the manifestation and natural history of imminent pediatric

38 o phenotypic variability in clinical disease manifestation and provide insight into potential mechani

39 however, the mechanisms underpinning disease manifestation and the specificity of the subunits mutate

40 are often challenging because of its varied manifestations and difficulty in interpretation of serol

41 This Review discusses the neurological manifestations and emerging therapies for the CNS compon

42 nd fluids, which contributes to the clinical manifestations and epidemiology that have been observed

43 The change in clinical manifestations and management over the past 2 decades sh

44 (IL-6) activity, may be related to clinical manifestations and pathophysiology of schizophrenia.

45 The ocular manifestations and sequelae of Zika virus infection are

46 be done to improve awareness of its clinical manifestations and the potential of therapeutic interven

47 sue diagnosis of ECD that showed intraocular manifestations and were imaged at baseline and follow-up

48 It is heterogeneous in etiology, clinical manifestations, and course.

49 predictor of HFpEF risk, associated clinical manifestations, and long-term outcomes.

50 , pharmacologic treatments, extra-intestinal manifestations, and surgeries in relation to age of IBD

51 enia, and coincident clinical and laboratory manifestations, and to provide guidance for dealing with

52 us was observed before the onset of allergic manifestations, and was associated with respiratory alle

53 Although HD is monogenic, its molecular manifestation appears highly complex and involves multip

54 /or this remarkable heterogeneity in disease manifestation are poorly understood.

55 ic leukaemia (CLL), but its functions in CLL manifestation are still unclear.

56 A number of cerebral manifestations are associated with JC polyomavirus (JCPy

57 It is not yet altogether clear whether these manifestations are caused solely by insufficient circula

58 Intraocular manifestations are rarely observed in association with E

59 Manifestations are varied, depending on the extent of CN

60 We sought to understand the clinical manifestations associated with the X-linked CGD carrier

61 to participants with NPC1 with neurological manifestation at the National Institutes of Health (NIH)

62 le individuals, advanced stage and bilateral manifestation at the time of diagnosis, and aggressive c

63 The burden of disease manifestations at 1 year was lower for patients in this

64 mission, pharmacologic remission, or minimal manifestations based on the Myasthenia Gravis Foundation

65 f this study was to compare the acute ocular manifestations between SJS and TEN.

66 airments of cognitive function are important manifestations, but the underlying pathology is unknown.

67 on between the PM2.5 exposure and skin aging manifestations by linear regression.

68 Life-threatening manifestations can develop in a small proportion of pati

69 dysregulation, setting the stage for disease manifestations characteristic of M. gallisepticum infect

70 o the well-described anatomic and neurologic manifestations, clinicians are now describing infants wi

71 sidered rare disorders with protean clinical manifestations, considerable advances in the understandi

72 o describe patient characteristics, clinical manifestations, disease course including viral replicati

73 The ocular manifestations documented using multimodal imaging allow

74 In contrast, mutants with CNS manifestations (F51L, E102del, V139M, R142Q, R142W, R164

75 d those with only autoimmune or inflammatory manifestations had median %DHR(+) values of 39% (n = 31;

76 between indoor air pollutants and skin aging manifestations has ever been shown.

77 The patients were diagnosed by clinical manifestations, histopathology, and immunoepitope mappin

78 rome, or with BMF kidney tumours as the only manifestation; however, their impact on FLCN function re

79 hallmark of tuberous sclerosis complex (TSC) manifestations; however, the genesis of these abnormalit

80 ings represent the substrate of the clinical manifestations (i.e. myoclonus) of the photoparoxysmal r

81 rations in the striatum and related clinical manifestations (i.e., craving and persistence of unhealt

82 unrelated families with overlapping clinical manifestations identified loss-of-function and missense

83 e disorder, including demographics, clinical manifestations, imaging features, natural course, and vi

84 se-free survival, indicating subclinical CNS manifestation in most patients.

85 us erythematosus is a disfiguring and common manifestation in systemic lupus erythematosus, and the e

86 Neurological manifestations in 95 patients were (in decreasing freque

87 tion of medullary and extramedullary myeloma manifestations in a murine xenograft model in vivo.

88 esidual alpha-GalA activity and developed FD manifestations in adulthood.

89 The most typical clinical manifestations in all 5 patients were sleep disturbances

90 kg, IP) dose-dependently exacerbated TS-like manifestations in D1CT-7, but not wild-type littermates;

91 s, possibly resulting in more severe disease manifestations in flavivirus immune vaccinees such as An

92 in levels has been shown to mitigate disease manifestations in mice.

93 ent need to evaluate and document ophthalmic manifestations in patients for timely management of this

94 ell-modified DCs ameliorated cardinal asthma manifestations in preventive and therapeutic protocols t

95 s associated with increased risk of allergic manifestations in the offspring generation, but not amon

96 Such extracardiac manifestations, in addition to other late complications

97 Additional ophthalmic manifestations included reduced brow hair, madarosis, an

98 s been linked to unusual and severe clinical manifestations including microcephaly in fetuses of infe

99 With severe disease manifestations including microcephaly, congenital malfor

100 s were positively associated with skin aging manifestation, including score of pigment spots on foreh

101 clude a spectrum of neuromuscular and ocular manifestations, including reduced vision with retinal de

102 rity of these patients will have eye-related manifestations, including visual loss from the optic ner

103 anic materials, one particularly significant manifestation is the spin-entangled triplet-pair state,

104 vision, and adequate knowledge of its ocular manifestations is of substantial importance to diabetic

105 to the femoral head, and one of the cellular manifestations is the endoplasmic reticulum (ER) stress.

106 Few data are available on its clinical manifestations, laboratory findings, and outcomes of tho

107 in human populations, but do not induce IPEX manifestations, may have unappreciated consequences in o

108 at onset of various forms of G1D, associated manifestations, natural history, treatment efficacy, and

109 To describe a family with cutaneous manifestations not previously described in patients with

110 NET formation may contribute to inflammatory manifestations observed in patients with AT, Artemis def

111 s scapulothoracic crepitus or bursitis, is a manifestation of a mechanical abnormality of the scapulo

112 We further attempt the synthetic manifestation of a temporally programmable self-assembly

113 ether deemed a prolonged learning curve or a manifestation of a volume-outcome relationship, suggeste

114 esence of peanut-specific IgE antibodies and manifestation of acute anaphylaxis on challenge.

115 roposed - the audience - and its role in the manifestation of affect is discussed using a cyberbullyi

116 nd to decline during aging, facilitating the manifestation of aggregate deposition diseases.

117 3D organotypic cultures, and resulted in the manifestation of an undifferentiated basal/stem cell-ass

118 RE3], it enhances propagation and phenotypic manifestation of another prion, [PSI(+) ].

119 M1F and CAMK2G in stress- and trauma-related manifestation of anxiety and depression across species.

120 ery with (n=131) or without (n=128) clinical manifestation of ASCVD.

121 ascular occlusive disease (PVOD) is a common manifestation of atherosclerosis, and it has a high rate

122 Polycystic liver disease is a well described manifestation of autosomal dominant polycystic kidney di

123 le decoy receptor for TNF-alpha, delayed the manifestation of behavioral fever and promoted CyHV-3 re

124 emory impairment in Alzheimer's disease is a manifestation of brain pathologies such as accumulation

125 we detected mutations up to 15 months before manifestation of clinical progression (range, 2.9-15.4 m

126 reactions and pattern formation in space, as manifestation of collective behavior.

127 family history for depression and the later manifestation of depressive symptoms.

128 mental effects of ELS when applied after the manifestation of disease phenotypes.

129 nts with fCCM and may be a clinically silent manifestation of disease.

130 The most common clinical manifestation of early Lyme disease is the erythema migr

131 forebrain glutamatergic neurons promotes the manifestation of endophenotypes related to psychiatric d

132 r caspase-1-mediated IL-1beta release in the manifestation of FMF.

133 this domain has focused on a second possible manifestation of generalization, wherein the knowledge o

134 y relaxing strings and vice-versa - a direct manifestation of heterogeneous dynamics.

135 f these genes during the early developmental manifestation of heterosis under fluctuating environment

136 her this recurrent amplification is solely a manifestation of increased fitness resulting from random

137 on hybrid modes with temperature, which is a manifestation of increased plasmon-phonon coupling stren

138 f the prenatal occurrence of fever, a common manifestation of infection, with ASD risk.

139 g cancer occurs 95% of the time due to late manifestation of its symptoms, necessitating rigorous tr

140 The renal manifestation of JBTS is a juvenile-onset cystic kidney

141 used nearly exclusively on just one possible manifestation of learning generalization, wherein traini

142 The manifestation of liver disease in young infants may be d

143 s and pathogenesis of this poorly understood manifestation of malaria.

144 o PM2.5 on hepatic steatosis, a precursor or manifestation of metabolic syndrome.

145 llmark of metabolic syndrome (MetS) and each manifestation of MetS is related to atrial fibrillation

146 em are implicated in the etiopathogenesis or manifestation of neurodevelopmental, psychiatric and neu

147 ing multiple sclerotic fibromas, a cutaneous manifestation of PTEN (phosphatase and tensin homologue)

148 l TB (GITB) is a rare and potentially lethal manifestation of PTTB and may show delayed onset in rena

149 s between cell-wall recycling/repair and the manifestation of resistance to beta-lactam antibiotics i

150 the mutations was strongly supported by the manifestation of several known cancer hotspot mutations

151 It can be an important manifestation of severe diseases such as necrotizing ent

152 ells that are generated only in one sex or a manifestation of sex-specific differentiation of neurons

153 We show that 14 prevents manifestation of spatial memory deficits in chimeric Eco

154 Differences in patient survival and in the manifestation of specific pathways-including hypoxia, me

155 to efficient uphill proton transfer, being a manifestation of stochastic resonance.

156 ipheral artery disease is considered to be a manifestation of systemic atherosclerosis with associate

157 ; and in this way, behavior can be seen as a manifestation of the brain's integrative functions.

158 Such a rare scenario is argued to be a manifestation of the competition between the exchange in

159 ells that are responsible for initiation and manifestation of the disease.

160 of tongue-protrusion is not imitation, but a manifestation of the infant's arousal by the modeler's e

161 ith nonalcoholic steatohepatitis, which is a manifestation of the metabolic syndrome (MetS).

162 age apoptosis in plaques of these mice was a manifestation of the selective effect of TRPC3 on apopto

163 This is a clear manifestation of the transition from incoherent-phonon-d

164 In this Article, we demonstrate the manifestation of these effects in atomically-thin WS2 fi

165 cardiac death (SCD) is the most devastating manifestation of ventricular arrhythmias (VAs), and is t

166 d perhaps unifactorial, because they are all manifestations of a single underlying variable, namely,

167 going pars plana vitrectomy (PPV) for severe manifestations of active proliferative diabetic retinopa

168 idge microscopic cell failure to macroscopic manifestations of aging.

169 ome severity and were worse with more severe manifestations of alcohol withdrawal syndrome.

170 ed gaps in knowledge were expressed for most manifestations of allergy with a correspondingly high se

171 patients suffering from respiratory and skin manifestations of allergy, but the routes and mechanisms

172 These phenotypes recapitulate the clinical manifestations of arCRD patients.

173 The manifestations of Aspergillus infections include invasiv

174 r, the relationship of thyroid function with manifestations of atherosclerosis remains unclear.

175 candidate for the treatment of the clinical manifestations of atherosclerosis.

176 suppressive function leading to the clinical manifestations of BHD, whereas the FLCN K508R mutant pro

177 multifocal (BMF) kidney tumours and clinical manifestations of Birt-Hogg-Dube (BHD) syndrome, or with

178 suggests that cerebral microinfarcts can be manifestations of both small vessel and large vessel dis

179 ility) as well as the various early and late manifestations of cerebral small vessel disease (eg, mic

180 y linked to magnetic resonance imaging (MRI) manifestations of cerebrovascular disease, such as lacun

181 ogical shifts constitute one of the clearest manifestations of climate warming.

182 Few monogenic causes for severe manifestations of common allergic diseases have been ide

183 To report the ocular manifestations of congenital Zika syndrome with microcep

184 Ophthalmic manifestations of congenital Zika syndrome.

185 l patient presenting with different clinical manifestations of coronary atherothrombosis, in light of

186 The clinical manifestations of DED can be highly variable; hence the

187 pneumonia and bacteremia as the most common manifestations of disease.

188 Behavioral manifestations of drug-seeking behavior are causally lin

189 1beta and the clinical and neuropathological manifestations of EAE disappeared in miR-142 knock-out m

190 Detailed pathophysiological manifestations of early disease in the context of predia

191 Rare intraocular manifestations of ECD confirmed on histopathology can be

192 Intraocular manifestations of ECD seen on multimodal imaging include

193 ture detailing risk factors for and clinical manifestations of EVD, laboratory and other investigatio

194 Nrf2 target genes, and can also suppress the manifestations of experimental autoimmune encephalomyeli

195 d cortex are mostly responsible for clinical manifestations of FFI.

196 s range from subclinical infection to severe manifestations of focal or systemic disease.

197 Clinical manifestations of food allergy are largely mediated by I

198 focused on invasive illness, the most severe manifestations of GAS infection.

199 available for management of extraesophageal manifestations of gastroesophageal reflux disease (GERD)

200 developmental studies, might represent early manifestations of genetic liability.

201 as a protein-folding buffer that shapes the manifestations of genetic variation in model organisms.

202 SUMMARY BACKGROUND DATA: Extraesophageal manifestations of GERD include cough, laryngopharyngeal

203 t successes in conquering the acutely lethal manifestations of heart and vascular diseases.

204 view discusses the causes, epidemiology, and manifestations of HF in children with congenital heart d

205 This mechanism does not explain certain manifestations of HIV disease, such as immunodeficiency

206 are widely disrupted, thus causing clinical manifestations of horizontal gaze palsy, scoliosis, and

207 Clinical manifestations of hypothyroidism range from life threate

208 One of the most striking manifestations of increasing elevation is the abrupt tra

209 ing the microbiology, epidemiology, clinical manifestations of infection, treatment, and public healt

210 Allergic manifestations of inhaled Aspergillus include allergic b

211 n and anxiety frequently accompany the motor manifestations of isolated adult-onset focal dystonias.

212 rx1-cKO) would phenocopy skeletal and dental manifestations of late-onset HPP.

213 rovides a potential explanation for clinical manifestations of melioidosis that are geographically re

214 Although these manifestations of motor memories were initially demonstr

215 velopment of treatments for the neurological manifestations of MPS has been hindered by the lack of o

216 MS are more likely to have early subclinical manifestations of MS.

217 There are limited data on disease manifestations of mutant strains in children.

218 ertness are some of the most common nonmotor manifestations of Parkinson disease (PD) and currently h

219 mas should be added to the list of cutaneous manifestations of patients with the familial MTC type of

220 We sought to compare clinical manifestations of pertactin-deficient and pertactin-prod

221 We seek to study the manifestations of PH in children and to assess the feasi

222 One of the most obvious manifestations of polarity in epithelia is the subdivisi

223 be aware of the typical and atypical imaging manifestations of PRES in order to make an accurate diag

224 This study presents the typical and atypical manifestations of PRES on 3T MR images.

225 , were used to classify the images as having manifestations of pulmonary TB or as healthy.

226 In addition, extraesophageal manifestations of reflux are most effectively diagnosed

227 diagnosis, and treatment of extraesophageal manifestations of reflux, specifically cough due to refl

228 structural abnormalities resembling clinical manifestations of RTT.

229 host vasculature contribute to the cardinal manifestations of sepsis in profound ways.

230 to describe demographic factors and clinical manifestations of seropositive patients.

231 Abnormalities in dendritic spines are manifestations of several neurodevelopmental and psychia

232 ar1(-/-) mice before BCG infection prevented manifestations of severe BCG disease and maintained lung

233 ol can also be exploited in the treatment of manifestations of severe inflammation by exogenous admin

234 nistic and functional links among behavioral manifestations of sleep, wake, and sleep deprivation and

235 he brain mainly due to the strong behavioral manifestations of sleep.

236 ems that recapitulate mutations and clinical manifestations of specific PMDs are evaluated for their

237 The early motor manifestations of sporadic amyotrophic lateral sclerosis

238 re rapid TL attrition are widely regarded as manifestations of stress.

239 lomerulonephritis is one of the most serious manifestations of systemic lupus erythematous (SLE).

240 nd various subfactors representing different manifestations of the canonical process, is a fundamenta

241 ease trichodysplasia spinulosa, we show that manifestations of the causative polyomavirus (TSPyV) occ

242 complete resolution of pruritus and clinical manifestations of the disease, as well as normalization

243 ck of efficacious treatments targeting renal manifestations of the disease.

244 tivation patterns, associated with different manifestations of the superordinate brain activation/dea

245 The versatile manifestations of these highly contagious organisms rang

246 neural activity, but the specific behavioral manifestations of these reported changes remain elusive.

247 Our aim was to identify the early childhood manifestations of this liability in a UK population-base

248 Manifestations of this syndrome can vary from the absenc

249 We find that these phenomena are manifestations of unexpected in-plane anisotropy in the

250 L. (L.) amazonensis from dogs with clinical manifestations of visceral leishmaniasis in Governador V

251 sease known as Majeed syndrome, the clinical manifestations of which are ameliorated by strategies th

252 intestine could account for gastrointestinal manifestations of Wilson disease.

253 To document the ocular manifestations of xeroderma pigmentosum (XP), presenting

254 had moderate disease, and 27 (20.6%) severe manifestations of ZIKV infection.

255 table and heterogeneous mental illness whose manifestations often include impulsive and risk-taking b

256 known about the full spectrum of phenotypic manifestations or how LVH influences disease expression.

257 ay be due to increased recognition of ocular manifestations, or a true increase in ocular syphilis.

258 We analyzed the causative PPI, clinical manifestations, organ involvement, treatment, and compli

259 he diverse roles of netrin-1, the absence of manifestations other than CMM in NTN1 mutation carriers

260 f glomerular pathologies without extra-renal manifestations, otherwise known as nail patella-like ren

261 The children with allergic manifestations, particularly asthma, during childhood ha

262 ciated with milder disease, yet neurological manifestations persisted in 3 individuals.

263 us consequences, including severe congenital manifestations, persistent infection in the testes, and

264 f Zika virus (ZIKV) and its unusual clinical manifestations provided ground for speculative debate.

265 The clinical manifestations range from subclinical infection to sever

266 The disease has many clinical manifestations, ranging from severe malabsorption to min

267 These proarrhythmic manifestations, related to Ca(2+) /calmodulin-dependent

268 ever, mechanisms underlying its etiology and manifestations remain poorly understood.

269 ge dysplasia, but the mechanisms of skeletal manifestations remain unknown.

270 The visual sequelae of these ophthalmic manifestations remain unknown.

271 The treatment of inflammatory manifestations remains challenging because it can be ass

272 ing the incidence and spectrum of neurologic manifestations secondary to Zika virus (ZIKV) infection

273 ilized model of pathogenesis due to clinical manifestations similar to those for HIV-1 infection and

274 arrying this mutation developed neurological manifestations similar to those of human patients.

275 e dyskinesias were quite variable, but their manifestation slowed the clinical development of cell re

276 e most beneficial in the early, possibly pre-manifestation stage.

277 patterns have been associated with allergic manifestations such as eczema, but exact microbiome dysf

278 , and similar but often less severe clinical manifestations, such as dengue and chikungunya infection

279 congenital malformations ranging from severe manifestations, such as renal agenesis, to potentially m

280 Autoimmune manifestations, such as skin infiltration and autoantibo

281 ells, although the heterogeneity of clinical manifestations suggests that patient, donor, and transpl

282 der (HAND) remains an important neurological manifestation that adversely affects a patient's quality

283 entification of classes with common clinical manifestations that are hidden under the current periodo

284 ation between rs1801198 and MMA and clinical manifestations that are linked to a decreased availabili

285 ctory process showing age-dependent clinical manifestations that are mechanistically undefined.

286 Although rare, ophthalmologic manifestations that are rapidly recognized and adequatel

287 gin decades before the onset of the clinical manifestations, the study of the cortical distribution o

288 hies have similar morphological and clinical manifestations, their outcomes differ significantly.

289 c systems is a known path leading to disease manifestation, therefore we hypothesized that proteases

290 ports have also indicated other neurological manifestations to be associated with ZIKV, including mye

291 higher sensitivity than the use of clinical manifestations to detect severe malaria, making it a pro

292 mes higher, and the risk of other autoimmune manifestations was approximately 10 times higher.

293 Occurrence of extra-intestinal manifestations was similar in elderly and adult patients

294 al phenotype, including severe hair and nail manifestations, we scrutinized the exome sequencing data

295 Ocular manifestations were more prevalent among syphilis patien

296 No detectable clinical manifestations were observed.

297 These manifestations were prevented by antibiotics and reverse

298 al model that develops progressive pulmonary manifestations when infected with MERS-CoV would advance

299 udinal studies linking eczema as the initial manifestation with progression to hay fever and then ast

300 espective of the type of aspirin sensitivity manifestation, with indications to undergo coronary angi