ライフサイエンスコーパス: manipulation

1 vity changes, were the primary outcome of SC manipulation.

2 efficient, and flexible strategy for genome manipulation.

3 s, and offers a synthetic handle for further manipulation.

4 the substrate surface manipulation, and cell manipulation.

5 applications such as micro hand for droplet manipulation.

6 re amenable to behavioral or pharmacological manipulation.

7 ersification without requiring postsynthetic manipulation.

8 by enabling more flexibility in polarization manipulation.

9 and altogether avoid preactuation mechanical manipulation.

10 on, microRNA delivery, and molecular pathway manipulation.

11 und imaging and therapy or acoustic particle manipulation.

12 ormation and its classical analog of secrecy manipulation.

13 PSMA and sodium bicarbonate, with no further manipulation.

14 ertoire of potential targets for therapeutic manipulation.

15 n appealing but underinvestigated microbiota manipulation.

16 related targets suitable for pharmacological manipulation.

17 al representations in response to contextual manipulation.

18 ers which are difficult to study by germline manipulation.

19 e case, strong limitation across our habitat manipulations.

20 ctivity that mimic those produced by chronic manipulations.

21 pects of the seasonal cycle or photoperiodic manipulations.

22 physiological recordings and pharmacological manipulations.

23 after undergoing an acute stress or control manipulation a week later; salivary cortisol was measure

24 physical cellular changes resulting from NCR manipulation affect the response to IRE at varying frequ

25 None of these manipulations affect fear acquired as a result of direct

26 nalization and tube formation, although such manipulations affect the geometry of invagination.

27 In the second experiment, we show that this manipulation also disrupts the ability of a cue to promo

28 Using a series of in vitro sperm manipulation and competition experiments, we show that r

29 entific inquiry, including network dynamics, manipulation and control of brain networks, and integrat

30 ffered by 2D crystals are discussed, such as manipulation and control of quantum degrees of freedom (

31 ting discoveries within the field of in vivo manipulation and dynamics of single molecule and organel

32 ysical properties is transforming the study, manipulation and evolution of proteins, and is enabling

33 plied nonlinear and quantum optics, enabling manipulation and interaction of quantum signals without

34 Optical manipulation and label-free characterization of nanoscal

35 es another trade-off between fine structural manipulation and manufacturing complex shapes in practic

36 hput, microfluidic-based assay for automated manipulation and on-chip monitoring and analysis of stim

37 context of micro-electronics, the real-time manipulation and placement of components using optics al

38 isions and the potential pitfalls related to manipulation and privacy.

39 idobacteria, though recalcitrance to genetic manipulation and scarcity of molecular tools has hampere

40 e of the art and future opportunities in the manipulation and stability of these materials, their fun

41 pposed, adaptations that facilitated precise manipulation and tool use.

42 ents of interface fluid after final surgical manipulations and immediately before leaving the operati

43 s based on recruitment data from the climate manipulations and long-term observations of adult popula

44 implement effective agricultural microbiome manipulations and management strategies, which, in turn,

45 h as behavioral responses to pharmacological manipulations and spike timing statistics.

46 Here we used in vivo opto/chemogenetic manipulations and trans-synaptic tracing of genetically

47 uisition and analysis, the substrate surface manipulation, and cell manipulation.

48 nstrumentation are improving the production, manipulation, and scientific understanding of such remed

49 for precise behavioral measurements, genetic manipulations, and recording and manipulation of neural

50 for noninvasive imaging, sensing, and light-manipulation applications, specifically focusing on prob

51 onstrate that the experimental effects of SC manipulation are entirely consistent with the SC control

52 l, more sophisticated techniques for genetic manipulation are facilitating the development of animal

53 ffects on learning elicited by each of these manipulations are fully dependent on depletion of kynure

54 ogical recordings and concurrent optogenetic manipulations are improving our understanding of the rol

55 during power grip compared with fine finger manipulations are largely cortical in origin and suggest

56 itability during gross more than fine finger manipulations are largely cortical in origin and that th

57 agnetic (EM) wave and different polarization manipulations are required for varied optical applicatio

58 ry proteins, and analysis of single filament manipulation assays.

59 nner materials and yields rules for particle manipulation at the microscale.

60 Stereoselective manipulations at the C1 anomeric position of saccharides

61 acterize cells with minimal perturbation and manipulation, at the benefit of sample recovery and re-e

62 us seems to partition the learning of object manipulation between the object and the body.

63 ts inconsistency in the occurrence of vector manipulation but also may reflect incomplete information

64 This substantial velocity manipulation by anisotropy engineering is important in d

65 Behavioral manipulation by parasites has also been shown for mice,

66 f a wider inquiry concerning host and vector manipulation by plant and animal pathogens and parasites

67 terostructure opens a new route to efficient manipulation by radiation, transmission, absorption, and

68 Scanning tunnelling microscopy and atomic manipulation can be used to assemble a two-dimensional q

69 nstrate that fatty acid biosynthesis pathway manipulation can help overcome the gemcitabine resistanc

70 t of nutrient exchange/feeding sites include manipulation centered on endocycle entry at the G2-M tra

71 Using neuron-specific manipulations combined with immunocytochemistry, paired

72 an important pool of transcripts where their manipulations confer a better performance of wheat varie

73 Such manipulation could be employed to achieve mobile informa

74 portunity for new therapeutic targets, whose manipulation could be used to mitigate ophthalmic diseas

75 al scale circuit mechanisms, and how circuit manipulations could lead to new treatments of neurologic

76 trial correlational analysis and optogenetic manipulation demonstrate that facilitation in the IpN dr

77 neurons, and optogenetic and pharmacogenetic manipulations demonstrate that several peptide markers (

78 Our results confirm that mating system manipulation disproportionately influences sex-biased ge

79 With no other manipulations, Dnmt3a+/- mice developed myeloid skewing

80 Activity-manipulations during naturally evoked proboscis extensio

81 antation in vivo arises from artificial cell manipulations ex vivo.

82 rs, and that dynamics are a critical axis of manipulation for causal optogenetic studies.

83 of maize line B73, and may reflect pathogen manipulation for nutrient acquisition and/or unsuccessfu

84 lysis of videomicroscopic recordings offer a manipulation-free and efficient characterization of cont

85 and methods in protein biophysics for sample manipulation, functional and structural studies, detecti

86 ong the metasurface sets its nontrivial beam manipulation functionality within a limited-angle incide

87 netic solid phase substrates for biomolecule manipulation have become a valuable tool for simplificat

88 findings therefore support the parasite host manipulation hypothesis.

89 he importance of understanding how autophagy manipulation in a tumor cell can have both cell-autonomo

90 odel organisms and have eluded culturing and manipulation in the laboratory.

91 ding of signaling networks and their precise manipulation in various contexts.

92 Using cell-type-specific optogenetic manipulations in behaving animals, we show that dendrite

93 3 case studies of experimental precipitation manipulations in grasslands worldwide.

94 tudies evaluating treatments or experimental manipulations in preclinical experimental biomedicine al

95 We carried out dynamic force manipulations in silico on a variety of coiled-coil prot

96 and behavioral hypotheses using a variety of manipulations, including gene overexpression, CRISPR/Cas

97 This manipulation increased one type of sensory hair cell (ta

98 Region-specific manipulations indicate that CSNs from caudal or rostral

99 king of responses to drivers with comparable manipulation intensity was as follows: biodiversity>graz

100 Here we show that manipulations involving striatal D2R signaling coincide

101 olution of 27c followed by further synthetic manipulations involving the carbamate formation, lactone

102 f taxa that is replenished only when dietary manipulation is accompanied by exposure to a healthier m

103 An influential theory of vWM proposes that manipulation is carried out by a central executive while

104 The most common reproductive manipulation is cytoplasmic incompatibility, which resul

105 technologies, but their direct detection and manipulation is rather challenging.

106 One method for achieving such manipulation is the parallel actuation of many microrobo

107 We used a combination of habitat manipulation, land-use and habitat surveys, molecular ge

108 le acceleration, multi-particle trapping and manipulation, laser machining, and laser material proces

109 ettings (i.e., genetic propensity or dietary manipulation) lead to the recruitment of CD36(+)(high) m

110 y evidence), massage, acupuncture, or spinal manipulation (low-quality evidence).

111 apy, cognitive behavioral therapy, or spinal manipulation (low-quality evidence).

112 mitochondrial failure rescue by cardiolipin manipulation may be a new intriguing target in treatment

113 Dielectrophoresis is one manipulation method for separating SWNTs based on dielec

114 s eliminating the need for additional sample manipulation, microchip redesigns, and/or system expansi

115 ning the risk of metastatic disease, and its manipulation might offer a new possibility for diminishi

116 Either manipulation modulates the electron density of the pair

117 oncepts to coat surfaces with quorum-sensing-manipulation molecules as a method to control collective

118 Thus, although acute manipulations more likely reveal basic gene functions, d

119 Here, we report the coherent manipulation of a qubit, which is based on the two valle

120 tration of altering silica structure through manipulation of a single gene.

121 physiology and survival of neurons following manipulation of Akt and several downstream targets, such

122 2), our system enables parallel, independent manipulation of alleles targeted by Cas9 and traditional

123 that PDH could arise as a new target for the manipulation of allergic diseases.

124 involve extensive genomic and/or epigenomic manipulation of autologous or allogeneic cells.

125 c activity can occur in the dark through the manipulation of auxin and cytokinin activity as well as

126 mpathetic nerve activity and pharmacological manipulation of blood pressure, we show that veterans wi

127 BRS was tested using pharmacological manipulation of BP via the Modified Oxford technique at

128 Direct manipulation of brain activity can be used to investigat

129 Manipulation of canonical endocytic pathways only slight

130 prompt the consideration for pharmacological manipulation of Cav1.2 in neuropsychiatric disorders wit

131 Thus, manipulation of CD55 activity to increase inhibition of

132 nstrated potential as a tool for optogenetic manipulation of cell-signaling pathways involving cyclic

133 l mechanisms has come to depend upon genetic manipulation of cells and organisms, relying upon cellul

134 e in vivo tumor ablation through a molecular manipulation of cellular morphology before IRE applicati

135 Viral manipulation of cellular proteins allows viruses to supp

136 Altogether, our results suggest that manipulation of cellular resource allocation is a key co

137 tive potential of meningeal LVs should allow manipulation of cerebrospinal fluid drainage and neuropa

138 interpreting results from investigations of manipulation of CysC concentration as an AD therapy.

139 terials, such as semiconductors, via careful manipulation of defects has led to extraordinary advance

140 Thus manipulation of DISC1 levels via the UPS may provide a n

141 Mechanical manipulation of DNA hairpins with an engineered sequence

142 programmable molecular scalpels for surgical manipulation of DNA.

143 ition and to further develop the therapeutic manipulation of dysfunctional rhythmic activity subtendi

144 Furthermore, manipulation of each population mediates either social w

145 ic meta-atoms is proposed for ultra-wideband manipulation of electromagnetic (EM) waves.

146 Manipulation of extracellular glycine by blocking either

147 of wood-decomposing fungi using a factorial manipulation of fungivore (Folsomia candida) presence, n

148 satile tuning of geometrical frustration and manipulation of ground state configurations.

149 nities for more selective, disease specific, manipulation of GSK3.

150 ns with channelrhodopsin for the optogenetic manipulation of hippocampal circuitry with light.

151 techniques, we studied the effect of genetic manipulation of hypothalamic GRP78.

152 e bacterial community may be involved in the manipulation of induced defenses in wild and cultivated

153 The modulation of chiroptical responses by manipulation of input powers incident on chiral metamate

154 ble ligand, such as DNA, would allow for the manipulation of interparticle interactions.

155 n functionalization with polar groups allows manipulation of ion transport and ion-to-electron transd

156 and-structure engineering open prospects for manipulation of lasing characteristics such as direction

157 ith electrical tunability offering real-time manipulation of light and serving as multifunctional dev

158 roximately 100 nm and 2 microm, enabling the manipulation of light in the visible and infrared range.

159 On the other hand, manipulation of magnetism in antiferromagnetic (AFM) bas

160 The manipulation of magnetization by spin-current occurs thr

161 This may facilitate the targeted manipulation of metabolic routes in crops for agricultur

162 ittle has been achieved for the atomic-level manipulation of metallic nanomaterials.

163 be common among commensal bacteria and that manipulation of microbiota genes encoding metabolites th

164 However, manipulation of modular type I polyketide synthases (PKS

165 Manipulation of nanoparticles in solution is of great im

166 Changes in body-representations by the manipulation of natural sounds produced when one's body

167 ts, genetic manipulations, and recording and manipulation of neural activity noninvasively and at sin

168 dynamics and for the genetic and functional manipulation of neural circuits in vivo without adverse

169 long-term functional studies and the genetic manipulation of neural networks.

170 by designer drugs) is widely used for remote manipulation of neuronal activity in freely moving anima

171 tools for in vivo labeling, monitoring, and manipulation of neurons were applied to this species.

172 Manipulation of neutrophil membrane composition by CyaA-

173 Manipulation of niche factors influencing the distributi

174 Developmentally, environmental manipulation of OL progenitor cells (OPCs) has profound

175 Using the metacanvas, dynamic manipulation of optical waves is demonstrated for light

176 or reductions, has an essential role in the manipulation of organic matter.

177 Here we first demonstrate that manipulation of peripheral TNF-alpha in the context of a

178 hanistic understanding into the behavior and manipulation of phosphate monoesters in molecular biolog

179 Cell-specific manipulation of PKC-2 activity revealed that thermotaxis

180 Pharmacological manipulation of PKM2 activity with TEPP-46 and shikonin

181 Genetic manipulation of PTEN status confirmed a mechanistic role

182 The control and manipulation of resonances is the key element in designi

183 efforts to improve crop performance via the manipulation of root and shoot branch growth angle.

184 redox biology may enable precisely targeted manipulation of ROS for effective medical therapies agai

185 Mice with manipulation of serotonin 1B receptor (5-HT1BR) expressi

186 Coherent manipulation of shallow nitrogen-vacancy (NV) color cent

187 ol for detecting the effects of experimental manipulation of social attributes and sub-lethal effects

188 We used metabarcoding and experimental manipulation of soil microbiomes to investigate the impa

189 Genetic manipulation of SPL4 led to altered plant architecture w

190 To enhance genetic manipulation of Streptococcus sanguinis, we have develop

191 parameters, and are relevant for the optical manipulation of strongly correlated systems.

192 ior, and introduce a new methodology for the manipulation of target-specific neural projections.SIGNI

193 ment of genetic technologies that permit the manipulation of targeted sets of neurons in the brains o

194 These findings demonstrate that manipulation of the AFM Neel-order magnetization directi

195 Manipulation of the airway microbiome, particularly in e

196 ce on proximate cells, thus enabling gentler manipulation of the cells without the need of physical c

197 ditioning or epigenetic programming, and the manipulation of the coral microbiome) as a means to enha

198 Manipulation of the cross-talk between granulocytes and

199 a new synthetic approach that enables facile manipulation of the density and distribution of grafts i

200 Manipulation of the Diels-Alder adducts provides the des

201 fiber membrane can be facilely tailored via manipulation of the dope and bore fluid formulations.

202 experimental system that allowed the genetic manipulation of the essential A6L gene.

203 Moreover, manipulation of the IL-10 signaling pathway represents a

204 Temporal manipulation of the in vitro environment and growth fact

205 metry condition can be achieved by a precise manipulation of the interplay between the gain and loss

206 Manipulation of the N-terminal sequence affected the amo

207 s obligate intracellular life style, genetic manipulation of the pathogen is difficult.

208 oli through molecular engineering, including manipulation of the protein transport pathway, codon opt

209 film electrochemistry reveals that targeted manipulation of the secondary coordination sphere of the

210 Focused ion beam milling allows manipulation of the shape and size of nanostructures to

211 Manipulation of the UCE, in a reporter minigene or via r

212 Optogenetic manipulation of the ventral tegmental area demonstrates

213 stalline thermal transport behaviour through manipulation of the vibrational landscape and orientatio

214 Here we describe manipulation of the X. laevis genome using CRISPR/Cas9 t

215 cked or be mimicked by selective optogenetic manipulation of these circuits.

216 This offers opportunities for the rational manipulation of these complex non-covalent interactions

217 Our data showed that manipulation of these critical pathway components led to

218 enable fine spatiotemporal interrogation or manipulation of these various functions.

219 reducing basal glutamate levels through the manipulation of xCT expression increases the surface exp

220 rtant significance for the establishment and manipulation of yeast strains with the Sup35 prion.

221 rformed during site-specific pharmacological manipulations of arousal levels may be used to study bra

222 textures and sinusoidal gratings) and three manipulations of certainty (orientation bandwidth, contr

223 rat neocortical pyramidal neurons by chronic manipulations of firing, but it is unknown whether they

224 Here, we report that manipulations of gonadal hormones do significantly alter

225 inase assays and genetic and pharmacological manipulations of GSK-3 have identified more than 100 put

226 we investigated the effects of DR as well as manipulations of insulin, mechanistic target of rapamyci

227 predictions require appropriate large-scale manipulations of intact, natural habitat that is open to

228 Manipulations of PIP2 levels affected both medium and sl

229 singing birds, we found that pharmacological manipulations of RA's inhibitory circuitry drove large s

230 l power, and preserved neural sensitivity to manipulations of sensory detail.

231 thus allowing axonal tracing and functional manipulations of the latter input-defined neuronal popul

232 ransfer paradigm, we assessed the effects of manipulations of the LHb and the LHb-RMTg pathway on tha

233 Using targeted genetic manipulations of the stomatal lineage and a combination

234 fibers likely to be affected by experimental manipulations of the striatum and the anterior limb of t

235 Further manipulations of these bromohydrins, by two diastereodiv

236 values independent of action, and unilateral manipulations of value are sufficient to mediate choice

237 s role in learning is less clear, with acute manipulations often producing inconsistent results.

238 Thus, these effects of VAPB and PTPIP51 manipulation on autophagy are a consequence of their ER-

239 ller species, so the observed effects of the manipulation on food web structure could not have propag

240 al mice and reveal different effects of each manipulation on motor behavior.

241 m was developed to assess oxic versus anoxic manipulations on in situ groundwater communities.

242 t the framework allows performing anatomical manipulations on white matter tracts for statistical inf

243 KLF2 manipulation, permeability measurements, small GTPase ac

244 We found that these manipulations, precisely targeted at the decision point,

245 In Experiment 2, a tool-use manipulation produced the opposite dissociation, modifyi

246 In a 6-month pharmacological hormone manipulation protocol, healthy, regularly menstruating,

247 sequences on those cells due to experimental manipulations, ranging from drugs of abuse to disease-ca

248 the importance of incorporating gradients of manipulations, ranging from extreme drought to extreme p

249 This manipulation regulated the availability of coarse-scale

250 specific networks for functional or genetic manipulations remains limited.

251 bspace of a higher dimensional system, whose manipulation requires precise control over the whole sys

252 Environmental manipulations showed these neurons to be anchored to env

253 The experimental manipulation significantly increased parasitism on B. dr

254 This astrocyte-specific genetic manipulation silenced the wake-promoting orexin neurons

255 approach within structures for lossless ion manipulations (SLIM) that enables both greatly enlarged

256 ferent levels in structures for lossless ion manipulations (SLIM).

257 ables a wide variety of data exploration and manipulation steps, and is extensible to many bioinforma

258 rtainty in calibration data through all data manipulation steps.

259 have evolved an impressive arsenal of light manipulation strategies that rely on the ability to gene

260 c structures, introduce electronic-structure manipulation strategies, and provide an overview of thei

261 imental framework for highly complex genetic manipulation studies in vivo.

262 fast, and sophisticated electromagnetic wave manipulation such as dynamic holography, focusing, beam

263 ns of many experiments using targeted genome manipulations such as knockouts or transgenics.

264 Genetic and acute pharmacological manipulations suggest that prolonged burst durations are

265 e in field common gardens and field rainfall manipulations, supporting a persistent effect of histori

266 ed research agenda includes examining vector manipulation syndromes comprehensively within pathosyste

267 rs, evaluating the effectiveness of putative manipulation syndromes under field conditions, decipheri

268 ecp2(het) through genetic or pharmacological manipulations targeting the GABAergic network restored g

269 from one to another equally valued reward, a manipulation that induces errors only in reward feature

270 function because pharmacological and genetic manipulations that affect prefrontal D3 receptors alter

271 In particular, experimental manipulations that alter intestinal microbiota impact ex

272 Three manipulations that altered BCR genes without affecting s

273 bout cell biology but also by clever genetic manipulations that directly and easily tested specific h

274 Experimental manipulations that reduced ambient levels had larger eff

275 For a similar intensity of manipulation, the effect of biodiversity loss was 4.0, 3

276 established and new technologies for genetic manipulation to achieve desired traits such as virus res

277 Here we use a large-scale factorial manipulation to assess the extent to which birds and ant

278 hort-lived presentations, or require genetic manipulation to facilitate membrane attachment.

279 he most generous harvest index (HI) and area manipulation to match a reported error, we are unable to

280 raging technology, theory, and environmental manipulation to optimize intervention approach.

281 We conducted an ecosystem-level temperature manipulation to quantify how coupling of stream ecosyste

282 Genetic manipulations to increase endosomal trafficking of synap

283 We therefore used a wide range of manipulations to investigate the dye uptake defect, incl

284 e infertility treatments-especially hormonal manipulations to stimulate or enhance oocyte production-

285 Nonetheless, in recent years, genetic manipulation tools have been successfully applied to ric

286 roassembly of micro-objects, and cooperative manipulation using multiple microrobots.

287 rchange format, facilitating data access and manipulation using Python and any other programming lang

288 Policy or environmental manipulation was present in all dissemination grants but

289 Each of these manipulations was without effect on the clathrin-mediate

290 Km and kcat requires multiple steps of data manipulation, we developed a computational approach (boo

291 nction with both pharmacological and genetic manipulation, we show that cytoplasmic dynein-1, which l

292 trophysiological recordings, and optogenetic manipulations, we show that putatively feedback neurons

293 a new approach to charged droplet trajectory manipulation which, when combined with hydrodynamic drag

294 g SWNTs were imaged during dielectrophoretic manipulation with fluorescence microscopy making use of

295 ptics enables quantitative analysis of light manipulation with individual optical devices.

296 These results pave the way for optogenetic manipulation with the spatial and temporal sophisticatio

297 Combining the aforementioned actin manipulations with Shot deficiency revealed a close corr

298 f limitations and usually require additional manipulations with the sample, such as dilution, separat

299 proteins are broadly expressed, their acute manipulation within defined cells has been difficult.

300 The device required only simple specimen manipulation without any dedicated instrumentation or sp