ライフサイエンスコーパス: mannan

1 mpletely blocked by the addition of EGTA and mannan.

2 ch showed it to be a phosphorylated branched mannan.

3 of preserving the carbohydrate structure of mannan.

4 albicans yeast cells and chemically purified mannan.

5 s of antibody reactive with Candida albicans mannan.

6 to DC-SIGN was completely competed off with mannan.

7 ong with low acetylation levels in xylan and mannan.

8 ffinities for C. albicans yeast and purified mannan.

9 years, possess an elaborate cell wall alpha-mannan.

10 ies of glycoside hydrolases that can degrade mannan.

11 ans, galactans, arabinogalactan proteins and mannans.

12 tivities of an LM glycan backbone, alpha(1-6)mannans.

13 lf of the phosphomannan attached to N-linked mannans.

14 eta1,6-branched beta1,3-d-glucan and free of mannans.

15 though further studies ruled out cytoplasmic mannans.

16 ed or if mannose receptors were blocked with mannans.

17 cytes mainly via recognition of cell-surface mannans.

18 for the observed accommodation of decorated mannans.

19 6 was observed, which was inhibited by yeast mannan (a known CD206 ligand), free mannose, and a block

20 by anti-DC-SIGN mAb and soluble DC-SIGN, and mannan, a natural ligand for DC-SIGN.

21 benefits of commensal fungi are mediated by mannans, a highly conserved component of fungal cell wal

22 differential recognition of the galactan or mannan acceptors prior to appropriate arabinosylation.

23 o glycan-binding proteins, confirmed by beta-mannan affinity electrophoresis.

24 gh titers of Ab recognizing C. albicans beta-mannan Ag.

25 Mannan-agarose purified RK(13) cell CRT (rCRT) selective

26 Finally, to assess whether the acid-stable mannan also affects cell surface hydrophobicity status,

27 to synthesize these glycoconjugates and beta-mannan, although at reduced levels.

28 n of FMS contains mainly the backbone of 1,4-mannan and 1,6-alpha-galactan and through the Fucalpha1-

29 In addition, the DC-SIGN ligand mannan and an anti-DC-SIGN antibody did not inhibit DC-m

30 Mannan and anti-CD206 antibody significantly decreased t

31 -7 in macrophages stimulated with zymosan or mannan and ATP.

32 te to the EPS matrix structure, while fungal mannan and beta-glucan provide sites for GtfB binding an

33 tically with Man5B in the hydrolysis of beta-mannan and carboxymethyl cellulose.

34 NCRD increased the efficiency of binding to mannan and changed the inhibitory potencies of competing

35 phobicity and substantial amounts of exposed mannan and chitin at the surface.

36 ng to loss of hydrophobicity and exposure of mannan and chitin polysaccharides.

37 Thus, differential surface expression of mannan and glucan may influence recognition of C. albica

38 We show here the distinct effects of mannan and glucan on complement activation and opsonopha

39 ), and Populus trichocarpa catalyze beta-1,4-mannan and glucomannan synthase reactions in vitro.

40 nsect cells, and each CslA protein catalyzed mannan and glucomannan synthase reactions in vitro.

41 Mannan and xylan concentrations were low in P. zonale an

42 important for understanding many aspects of mannan and xyloglucan biosynthesis.

43 multiple membrane spans, and their products (mannan and xyloglucan) accumulate in the Golgi lumen.

44 tion by Ig was inhibited by coapplication of mannan and, thus, likely to be mediated by C-type lectin

45 mechanism for binding of dectin-2 to fungal mannans and also to bacterial lipopolysaccharides, capsu

46 as a sugar-rich cell wall mainly composed of mannans and glucans.

47 bind Manalpha1-2Man in internal positions in mannans and other polysaccharides.

48 s as immunodominant epitopes in (1-->2)-beta-mannans and to the viability of a glycoconjugate vaccine

49 ayer enriched in mannosylated glycoproteins (mannan) and an inner layer enriched in beta-(1,3)-glucan

50 exhibit moderate affinity for cellulose and mannan, and bind tightly to the beta-1,4-linked glucose-

51 of Candida albicans (carbohydrate, purified mannan, and protein-rich fractions, etc.), as well as no

52 , the degree of acetylation of xylan, (gluco)mannan, and xyloglucan as well as overall cell wall acet

53 olysaccharides and the hemicelluloses xylan, mannan, and xyloglucan.

54 rhamnogalacturonan I), xyloglucans, xylans, mannans, and glucans.

55 BM families that targeted beta-glucans, beta-mannans, and the pectic polysaccharide homogalacturonan.

56 Mannan/anti-mannan immunoglobulin G, beta-D-glucan (BDG)

57 ese results suggest that naturally occurring mannan antibodies and the complement system are function

58 body to opsonophagocytic killing showed that mannan antibody in individual sera and antimannan immuno

59 An evaluation of the contribution of mannan antibody to opsonophagocytic killing showed that

60 ing cells by human neutrophils requires anti-mannan antibody, whereas ingestion of glucan-displaying

61 ion with homology modeling of the bound beta-mannan antigen suggested an optimum oligosaccharide for

62 a surface-associated phosphorylated branched mannan (APS) indicated that this locus is also downregul

63 The MW for glycogen and mannan are 604+/-0.002 kDa and 54+/-0.002 kDa, respectiv

64 ivities seen in the synthesis of the (1-->4)-mannan are congruent with the more open, ordered structu

65 ell wall components chitin and outer chain N-mannans are absent, based on genome content and experime

66 Mannans are also present in chloronemal and caulonemal f

67 Mannans are hemicellulosic polysaccharides that have a s

68 Mannans are hemicellulosic polysaccharides that have pre

69 array analysis of Arabidopsis indicated that mannans are present throughout the plant and are especia

70 D-galactose (Gal)-substituted (1-->4)-beta-D-mannans] are major cell wall storage polysaccharides in

71 In addition, we discuss the use of fungal mannan as a diagnostic marker of fungal disease.

72 ack of order in the structure of the (1-->2)-mannan, as compared to the high degree of order in the (

73 LM and the number of arabinan chains on the mannan backbone in LAM remain.

74 an synthase (ManS), that makes the beta-1, 4-mannan backbone of galactomannan, a hemicellulosic stora

75 ansferase involved in extending the alpha1-6-mannan backbone of LM intermediates.

76 ays a critical role in the elongation of the mannan backbone of mycobacterial and corynebacterial LM,

77 Galactomannans comprise a beta-1,4-mannan backbone substituted with alpha-1,6-galactosyl re

78 arides composed of a (1 --> 4)-linked beta-D-mannan backbone substituted with single-unit (1 --> 6)-a

79 tus, this polysaccharide is made of a linear mannan backbone with side chains of galactofuran and is

80 a-mannanase catalyzes endo-hydrolysis of the mannan backbone, a major constituent of woody biomass.

81 MS catalyzes the elongation of the mannan backbone, whereas GMGT action determines the dist

82 addition to alpha(1-->2)Man branching on the mannan backbones of LM and LAM, confirming the involveme

83 of alpha(1-->2)-linked Man branching on the mannan backbones of LM and LAM.

84 evalence of dual specificity for glucan- and mannan-based substrates in the GH5 family.

85 Prior blocking with anti-HAF antibody or mannan before coculture impaired viral trans-infection.

86 ajor polysaccharide constituents being alpha-mannan, beta-1,6 glucan, and beta-1,3 glucan.

87 Appending a mannan binding CBM27 to CjCE2C potentiated its activity

88 The data show that cellulose and mannan binding CBMs have the greatest impact on the remo

89 Measurement of mannan binding lectin (MBL) antigenic level and activity

90 Mannan binding lectin (MBL) is an innate immune mediator

91 nt, the pattern recognition molecules (PRMs) mannan-binding lectin (MBL) and ficolins complexed with

92 C1q and mannan-binding lectin (MBL) are not only recognition com

93 In teleost fish, the immune functions of mannan-binding lectin (MBL) associated protein (MAP) and

94 Mannan-binding lectin (MBL) is a component of the innate

95 Mannan-binding lectin (MBL) is an important protein of t

96 b, CR1 was reported to interact with C1q and mannan-binding lectin (MBL) likely through its C-termina

97 It is activated upon binding of mannan-binding lectin (MBL) or ficolins (H-, L-, and M-f

98 ght to occur via recognition of pathogens by mannan-binding lectin (MBL) or ficolins in complex with

99 activation by Neisseria gonorrhoeae via the mannan-binding lectin (MBL) pathway in normal human seru

100 t the soluble pattern recognition molecules, mannan-binding lectin (MBL), L-ficolin, and M-ficolin, w

101 The pattern recognition molecule, mannan-binding lectin (MBL), plays an important role in

102 ction of an endogenous complement inhibitor, mannan-binding lectin (MBL)-associated protein (MAp)44,

103 Mannan-binding lectin (MBL)-associated serine proteases,

104 oligomannose glycans on serum IgD and IgE to mannan-binding lectin (MBL).

105 found that the C7 rs6876739 CC genotypes and mannan-binding lectin (MBL2) gene polymorphisms of liver

106 way and absence of the LP complement protein mannan-binding lectin abrogates elastase-induced AAA.

107 Human beta-defensin 3 and mannan-binding lectin also blocked viral fusion by creat

108 in pathway (LP) showed that both ficolin and mannan-binding lectin can activate the LP through natura

109 omplement cascade but not the alternative or mannan-binding lectin pathways.

110 MASP1 encodes mannan-binding lectin serine protease 1.

111 etic deficiency in early complement, IgM, or mannan-binding lectin were characterized in a mesenteric

112 to ischemic Ag providing a binding site for mannan-binding lectin which subsequently leads to activa

113 he lectin activation pathway upon binding of mannan-binding lectin, ficolins, or collectin kidney 1 (

114 and factor H in the alternative pathway and mannan-binding lectin, mannan-binding lectin-associated

115 substrate complex consisting of glycan-bound mannan-binding lectin, MASP-2, and C4 is discussed.

116 to the same areas that stain positively for mannan-binding lectin, which suggests that the complemen

117 Mannan-binding lectin-associated serine protease 2 (MASP

118 n pathway deficiency, a mouse strain lacking mannan-binding lectin-associated serine protease-2 (MASP

119 mediated by direct cleavage of native C3 by mannan-binding lectin-associated serine protease-2 bound

120 Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can a

121 C2 bypass route is dependent on LP-specific mannan-binding lectin-associated serine protease-2.

122 We found that the complex bound to mannan-binding lectin-associated serine proteases (MASPs

123 lecules leading to the activation of zymogen mannan-binding lectin-associated serine proteases (MASPs

124 H-ficolin is found in plasma associated with mannan-binding lectin-associated serine proteases (MASPs

125 ternative pathway and mannan-binding lectin, mannan-binding lectin-associated serine proteases 1 and

126 In serum, CL-L1 was found in complexes with mannan-binding lectin-associated serine proteases, sugge

127 anism, which is conserved in C1r and also in mannan-binding lectin-associated serine proteases, the s

128 ution of blistering had a similar pattern in mannan-binding lectin-deficient and control mice and was

129 ys in this model, we injected C1q-deficient, mannan-binding lectin-deficient, and factor B-deficient

130 nd has ligand specificity similar to that of mannan-binding lectin.

131 ly reported for the lectin homologs SP-D and mannan-binding lectin.

132 Lectins like mannan-binding protein are part of the innate immune sys

133 Results also implicate the mannan-binding receptor Dectin-2 in regulating cPLA(2)al

134 hat C. albicans engages both beta-glucan and mannan-binding receptors on macrophages that act with My

135 cans where inactivation of genes involved in mannan biosynthesis has usually been linked to an attenu

136 This review focuses on O- and N-linked mannan biosynthesis in the fungal pathogen Candida albic

137 t NCgl1505 was involved in core alpha(1-->6) mannan biosynthesis of Cg-LM-A and Cg-LM-B, extending Ac

138 nclude that the MSR protein is important for mannan biosynthesis, and offer some ideas about its role

139 Because this protein is involved in mannan biosynthesis, we named it 'mannan synthesis-relat

140 CaMnt4 and CaMnt5 participated in N-mannan branching.

141 s with antibody specific for DC-SIGN or with mannan but not antibody specific for xCT, a cystine/glut

142 Next, removal of the surface-displayed mannan by acid treatment of periodate-borohydride cells

143 ring studies showed that metabolism of yeast mannan by B. thetaiotaomicron presents a 'selfish' model

144 es and that the masking of primary cell wall mannan by pectin is a potential mechanism for controllin

145 is blocked by specific inhibitors, including mannan, calcium chelators, and Abs to the lectin domain

146 In addition, although purified mannans cannot solely mediate the priming, the presence

147 f the GH130_1 subfamily would be involved in mannan catabolism, whereas the enzymes belonging to the

148 anched mannosyl residues, the alpha-6-linked mannan chain is terminated with an alpha-mannopyranose a

149 in N-glycosylated proteins that have shorter mannan chains.

150 onal antibody 3F8 inhibited C3 deposition on mannan-coated plates in MBL2 KI, but not wild-type, mice

151 n vitro, MBL/MASP complexes were captured on mannan-coated plates, and cleavage of a chromogenic thro

152 significant increase in sensitivity to both mannan competition and endoglycosidase H digestion compa

153 ebound to 2G12 was 10-fold more sensitive to mannan competition than gp120 that was not prebound in a

154 This work suggests that Con A-mannan complex could be potentially utilized for insulin

155 ed unambiguous identification of acid-labile mannan components.

156 Treatment with mannan considerably reduced infection of feline monocyte

157 chain length, whereas those for the (1-->2)-mannan consist of two groups with the formation of the t

158 softwoods, such as conifers and cycads, are mannans consisting of a 1,4-linked beta-mannopyranosyl m

159 ta, a molecular mechanism for utilization of mannan-containing nutrients by C. polysaccharolyticus is

160 akes them a resource for depolymerization of mannan-containing polysaccharides in the biofuel industr

161 MYB46 resulted in a significant increase in mannan content.

162 abinan chain attached near the middle of the mannan core is present in mature LAM and allow for an up

163 s of the number of arabinans attached to the mannan core of LM in two other mutants (DeltaembC and De

164 noside, had no activity, suggesting that the mannan core of LM was required for the activity of LM.

165 ages of the biosynthesis of the alpha(1-->6) mannan core of LM.

166 the addition of alpha(1-->2) branches to the mannan core of LM/LAM and that arrest of this branching

167 d exactly one arabinosyl substitution of the mannan core suggestive of the arabinosylation of a linea

168 omposed of only the phosphatidylinositol and mannan core.

169 T Rv2181 in the dual role of Man capping and mannan-core branching, and in the process generated a ra

170 f mannose receptor (MR) activity on MDM with mannan decreased the association of F. novicida and opso

171 anscriptome sequencing to gain insights into mannan degradation by the thermophilic anaerobic bacteri

172 ring seed germination and suggest a role for mannan degradation in tobacco.

173 in N-glycan maturation and microbiotal yeast mannan degradation, respectively.

174 The present study shows that this mannan-dependent resistance can be overcome by periodate

175 bit erythrocytes and precipitated with yeast mannan, dextran, and the high mannose-containing glycopr

176 Electrophoretic profiles of the acid-labile mannan differed only with hydrophobicity status, not ser

177 he CBMs that recognize beta-glucans and beta-mannans, differences in the conformation of conserved ar

178 Additionally, we found that, like mannan, different airborne allergens can effectively dow

179 Finally, ingestion of mannan-displaying cells by human neutrophils requires an

180 (zymosan and sheep erythrocytes coated with mannan (E(Man))) revealed that the convertases (ZymM1,C4

181 xpressing cells was largely blocked by yeast mannan, EDTA, or a DC-SIGN/L-SIGN-specific monoclonal an

182 In secondary cell walls, mannan esterification can prevent probe recognition of e

183 The most highly up-regulated genes during mannan fermentation occur in a cluster containing severa

184 a phosphatidylinositol anchor followed by a mannan followed by an arabinan that may be capped with v

185 oteins, which synthesize beta-(1-->4)-linked mannans found in the walls of many plant species, and CS

186 Indeed, we found that phosphatidylinositol mannan from M. tuberculosis inhibits macrophage response

187 -(1-->3)-mannohexaose, representative of the mannan from Rhodotorula glutinis, Rhodotorula mucilagino

188 lar weights (MW) of glycogen from Oyster and mannan from Saccharomyces cerevisiae are determined by s

189 A single i.p. exposure to mannan from Saccharomyces cerevisiae induced an acute in

190 s have the greatest impact on the removal of mannan from tobacco and Physcomitrella cell walls, respe

191 an synthases and support the hypothesis that mannans function in metabolic networks devoted to other

192 wed that longer chain of synthetic alpha(1-6)mannans gain better lectin's binding affinity.

193 be involved in A. thaliana in degradation of mannans, galactomannans, or glucogalactomannans.

194 e-linked immunosorbent assay with serotype A mannan generally paralleled reactivity with serotype B.

195 ohydrate-binding module directed against the mannan group of hemicellulose cell wall polysaccharides,

196 The recalcitrant mannan, however, was fully accessible to the GH26 mannan

197 several genes encoding enzymes for efficient mannan hydrolysis as well as a solute-binding protein (C

198 l glycone binding site more efficiently than mannan-hydrolyzing glycoside hydrolases in related enzym

199 spectra of trehalose, glycogen, glucose, and mannan, i.e., the major carbohydrates present in S. cere

200 Mannan/anti-mannan immunoglobulin G, beta-D-glucan (BDG) and polymer

201 gus was inhibited by beta-glucans but not by mannans, implicating a lectin-like activity in recogniti

202 tions identify an inhibitory role for intact mannan in complement activation.

203 o, only CjCE2C was active against acetylated mannan in Physcomitrella.

204 y reduced level of the virulence factor beta-mannan in the glucose transporter null mutants compared

205 lactan and with reduced amounts of xylan and mannan in the outer S2 (S2L) region of tracheids.

206 mannanase was independent of the context of mannan in tobacco cell walls, a significant proportion o

207 e bacterial aggregation and to bind to yeast mannan in vitro.

208 nition of epitopes/ligands, and detection of mannans in primary cell walls can be effectively blocked

209 affects the structure of the fungal N-linked mannan, in line with their predicted functions, and this

210 nted levels of the storage carbohydrate beta-mannan, increased cell size and increased growth as inse

211 he purified cell wall components zymosan and mannan induced caspase-1 activation and IL-1beta secreti

212 Hence, we propose that mannan-induced activation of macrophages leads to TNF-al

213 We investigated mannan-induced arthritis in SKG mice and how NADPH oxida

214 of mycobacteria with human macrophages, in a mannan-inhibitable fashion.

215 peritoneal Mphi, we identified an additional mannan-inhibitable receptor for zymosan that was distinc

216 not C. trachomatis serovar UW5 or L2, while mannan inhibited the growth of C. trachomatis, but not C

217 ation constants for Con A-glycogen and Con A-mannan interactions are KA=3.93+/-0.7x10(6) M(-1)/KD=0.2

218 even from their physical nature: the (1-->2)-mannan is a gum and the (1-->4)-mannan is a high melting

219 the (1-->2)-mannan is a gum and the (1-->4)-mannan is a high melting solid.

220 Mannan is a major cell wall component found in Candida s

221 Here we show that yeast alpha-mannan is a viable food source for the Gram-negative bac

222 By 28 DAP labeling of hetero-(1-->4)-beta-D-mannan is observed in the walls of the starchy endosperm

223 d to the high degree of order in the (1-->4)-mannan, is also evident from a comparison of the NMR spe

224 hestrate the depolymerization of yeast alpha-mannans, it is likely that the two enzymes target the be

225 -glucan to the immune system occurs when the mannan layer is altered or removed in a process called u

226 In wild-type C. albicans, the outer mannan layer of the wall masks the inner layer of beta(1

227 ated neutrophils with three soluble glucans, mannan, lipopolysaccharide, or a variety of cytokines re

228 nnobiose to 4-O-beta-d-mannosyl-d-glucose in mannan metabolism.

229 veral cell-wall polysaccharides (xyloglucan, mannans, mixed-linkage beta-glucan and xylans); however,

230 ition of a fungal cell wall component, alpha-mannan (Mn), an Mn (sugar) polymer, by the C-type lectin

231 N demonstrated the significance of alpha(1-6)mannan motif present in LM structure.

232 ESI-MS/MS results showed that the isolated mannan oligomers, MOS-III, MOS-IV, MOS-V and MOS-VI cons

233 A self-consistent model of beta-mannan oligosaccharides bound to a monoclonal antibody,

234 , that multivalently and selectively bind to mannan on the C. albicans cell surface to form crosslink

235 The influence of yeast mannan on the ecology of the human microbiota is unknown

236 rt a model whereby limited cleavage of alpha-mannan on the surface generates large oligosaccharides t

237 We demonstrate that MR senses mannan on the surface of attenuated Blastomyces dermatit

238 Although intact yeast display mannan on the surface, glucan, typically located in the

239 se, inhibit the interaction between SP-D and mannan, one of the well-studied hexose ligands for SP-D,

240 Upon binding to mannan or DNA in the presence of MASP-2, the CL-L1-CL-K1

241 phagocytosis of C. albicans cells displaying mannan or glucan.

242 affinity for cellulose but does not bind to mannan or glucomannan.

243 Upon treatment of DCs with mannan or LRP ligand alpha2-macroglobulin, we observed o

244 h alanine at this position failed to bind to mannan or maltose-substituted solid supports.

245 ficantly inhibited by the addition of either mannan or mannose.

246 narin (beta-1,3-glucan) but not sialic acid, mannan or pustulan mediated Hst 5 binding to C. albicans

247 rized grass pollen allergoids to nonoxidized mannan (PM) compared with glutaraldehyde-polymerized all

248 the weakening of plant tissues by degrading mannan polymers in the cell walls.

249 ecombinant CslA proteins produce beta-linked mannan polymers when supplied GDP-mannose.

250 Mannan polysaccharides and homologs of CslA genes appear

251 Mannan polysaccharides are widespread among plants, wher

252 ily have previously been shown to synthesise mannan polysaccharides in vitro when heterologously expr

253 rides, we show that molecular recognition of mannan polysaccharides present in intact cell walls is s

254 BoMan26A primarily formed mannobiose from mannan polysaccharides.

255 erm tissue, showing higher levels of galacto-mannan precursors in fenugreek endosperm.

256 One example is the beta-mannan present in the phosphomannan glycoprotein of Cand

257 the glycoside hydrolases encoded by the beta-mannan PUL and involved in the beta-mannan utilization p

258 ne at 343 (R343V) showed enhanced binding to mannan relative to wild type and R343A.

259 Allergoids conjugated to nonoxidized mannan represent suitable vaccines for AIT.

260 This phosphorylated branched mannan represents a novel polysaccharide that is immunol

261 the conserved fungal components zymosan and mannan require ASC and Cryopyrin for caspase-1 activatio

262 The hydrolysis of polysaccharides containing mannan requires endo-1,4-beta-mannanase and 1,4-beta-man

263 Direct fluorescence imaging using a mannan-specific carbohydrate-binding module and sequenti

264 anced its catalytic efficiency on glucan and mannan substrates by 175 and 1,600%, respectively.

265 ns and those microbes devoid of cell-surface mannan such as the gram-negative bacterium E. coli.

266 l gold particles was used to label the alpha-mannan sugar in the cell wall of the yeast Saccharomyces

267 ated response to fungal Ags was inhibited by mannan, suggesting involvement of MRs.

268 This binding was blocked by the addition of mannan, suggesting mannose receptor involvement in the D

269 Ca(2+) and by preincubation of DC-SIGN with mannan, suggesting that C1q binds to DC-SIGN at its prin

270 Blocking experiments with laminarin and mannan supported the conclusion that differences in cell

271 ose synthase (CESA4, CESA7, and CESA8) and a mannan synthase (CSLA9) genes.

272 y DNA (cDNA) clone encoding one such enzyme, mannan synthase (ManS), that makes the beta-1, 4-mannan

273 of two membrane-bound glycosyltransferases, mannan synthase (MS) and galactomannan galactosyltransfe

274 In addition, in vitro mannan synthase activity from the stems of msr1 single a

275 B46 (At5g12870) is a direct regulator of the mannan synthase CLSA9.

276 Previous studies led to the conclusion that mannan synthase enzymes in several plant species are enc

277 members of the CslA gene family encode beta-mannan synthases.

278 yield after the trisaccharide in the (1-->2)-mannan synthesis is attributed to steric interference by

279 nvolved in mannan biosynthesis, we named it 'mannan synthesis-related' (MSR).

280 n-1, was incorporated into the original beta-mannan tetanus toxoid conjugate providing a tricomponent

281 ive vaccine against Candida albicans, a beta-mannan tetanus toxoid conjugate showed poor immunogenici

282 y the tricomponent vaccine, but not the beta-mannan tetanus toxoid vaccine, showed activation of BMDC

283 e showed that the reducing end region of the mannan that is attached to inositol has 5-7 unbranched a

284 Its cell surface is enriched with mannan that is resistant to complement activation.

285 APS is a phosphorylated branched mannan that shares a common epitope with posttranslation

286 e to exogenous microbial components, such as mannan, that can induce and exacerbate Ps and PsA.

287 In the synthesis of the (1-->4)-mannan, the glycosylation yields and stereoselectivities

288 and conjugated to the fungal cell wall beta-mannan trisaccharide [beta-(Man)(3)] by novel saccharide

289 oncanavalin A (Con A) and glycogen and Con A-mannan using quartz crystal microbalance (QCM), cost and

290 ein and provides a framework for engineering mannan utilization capabilities for microbial fermentati

291 the beta-mannan PUL and involved in the beta-mannan utilization pathway in B. ovatus.

292 Mannan was absent from the highly lignified compound mid

293 The synthesis of the (1-->2)-mannan was achieved by means of the sulfoxide coupling p

294 phenomenon in parenchyma systems, and masked mannan was found to be a feature of cell wall regions at

295 oxide coupling protocol, whereas the (1-->4)-mannan was prepared using the analogous thioglycoside/su

296 homannan was almost completely absent, and O-mannan was severely truncated in the null mutant.

297 Xylan and mannan were detected in all lignified xylem cell types (

298 Full-length mouse Langerin-bound mannan, whereas DeltaE3Langerin and soluble bacterial re

299 ogy as well as the storage carbohydrate beta-mannan, which is an essential virulence factor for survi

300 o the inner Araf-alpha(1-->5)-Araf unit) and mannan (with fewer 6-Manp residues and more substitution