ライフサイエンスコーパス: mannose

1 ion at positions 3, 4, and 6 of the terminal mannose.

2 se NixJ (GH125), which removes the alpha-1,6-mannose.

3 y could be greatly inhibited by arginine and mannose.

4 influence on PTS sugar metabolism, including mannose.

5 ble of generating GDP-glucose as well as GDP-mannose.

6 to sites are unusual in terminating at high mannoses.

7 cromolar range for fullerenes with 12 and 36 mannoses.

8 ng asparagine (N)-linked paucimannosylation (mannose(1-3)fucose(0-1)N-acetylglucosamine(2)Asn).

9 volved in alpha-1,6 linked fucosylation, GDP-mannose 4, 6-dehydratase (Gmds) and to a lesser extent f

10 vo pathway, which requires the action of GDP-mannose 4,6-dehydratase (GMD) and GDP-L-fucose synthase

11 equires sequential reactions mediated by GDP-mannose 4,6-dehydratase (GMDS) and GDP-4-keto-6-deoxyman

12 equires sequential reactions mediated by GDP-mannose 4,6-dehydratase (GMDS) and GDP-4-keto-6-deoxyman

13 FDPEPS, ODPEPS, and BTPEPS were composed of mannose (5.75%, 5.52%, 6.97%), glucose (88.90%, 89.31%,

14 ds from the V1/V2 domain also expressed with mannose-5 glycans.

15 sorting nexin 1 (SNX1), as well as decreased mannose 6 phosphate receptor (M6PR), suggesting the impa

16 mplex, which recycles the cation-independent mannose 6-phosphate receptor (CI-MPR) from endosomes to

17 rk (TGN) transport of the cation-independent mannose 6-phosphate receptor (CI-MPR).

18 OCRL1 and IPIP27A localize to mannose 6-phosphate receptor (MPR)-containing traffickin

19 receptors, including the cation-independent mannose 6-phosphate receptor for lysosomal enzymes.

20 Inactivation of the mannose 6-phosphate receptor homology domain of OS9 had

21 trates that in the majority of instances the mannose 6-phosphate receptor homology domain of the gamm

22 uolar protein sorting 35 homolog), and M6PR (mannose 6-phosphate receptor) blocked PrP(C) internaliza

23 rs of transport vesicles (cation-independent mannose 6-phosphate receptor), late endosomes (Ras-assoc

24 nto cells via sortilin or cation-independent mannose 6-phosphate receptor, and facilitated the acidif

25 ilure of fission caused defective sorting of mannose 6-phosphate receptor, with consequently disrupte

26 Here, we demonstrate that mannose 6-phosphate receptor-mediated cellular uptake an

27 state localization of the cation-independent mannose 6-phosphate receptor.

28 ow visualization of endocytosis of mod2B via mannose 6-phosphate receptors and delivery of mod2B to l

29 ags newly synthesized lysosomal enzymes with mannose 6-phosphate recognition markers, which are requi

30 , an enzyme involved in the synthesis of the mannose 6-phosphate signal that targets acid hydrolases

31 These hydrolases acquire a mannose 6-phosphate tag by the action of the GlcNAc-1-ph

32 ates the initial step in the addition of the mannose 6-phosphate targeting signal on newly synthesize

33 or type 2 (IGF2) receptor (IGF2R) recognizes mannose 6-phosphate-containing molecules and IGF2 and pl

34 Among the 15 extracellular domains of the mannose 6-phosphate/insulin-like growth factor-2 recepto

35 tional tagging with N-glycans terminating in mannose-6-phosphate (M6P) residues.

36 Mannose-6-phosphate (M6P)-terminated oligosaccharides ar

37 tein NPC2, a cargo of the cation-independent mannose-6-phosphate receptor (CI-M6PR).

38 tion between SNX5 and the cation-independent mannose-6-phosphate receptor (CI-MPR).

39 ome-to-Golgi retrieval of cation-independent mannose-6-phosphate receptors (CI-MPR) in the soma is di

40 delivery was independent of high-mannose and mannose-6-phosphate receptors, which are exploited for d

41 D-mannose, a C-2 epimer of glucose, exists naturally in ma

42 tions of modifications (sulfonamide, biotin, mannose) against matched targets (carbonic anhydrase, st

43 ld (longest linear sequence) starting from d-mannose and (S)-propylene oxide as the source of the ste

44 ceptible to concentrated acid were rhamnose, mannose and arabinose.

45 The first examples of mannose and biotin ligands coupled to aqueous carboxy-fu

46 n cell-derived NS1, which displays both high mannose and complex type N-linked glycans, soluble NS1 s

47 not only to GlcNAc-peptide but also to high-mannose and complex-type N-glycans in the context of N-g

48 The 2,6-anhydro-heptitols derived from D-mannose and D-galactose are enantiomeric and are useful

49 Besides interacting specifically with high mannose and fucosylated neutral carbohydrate structures,

50 d by arabinose, xylose, and glucose, whereas mannose and galactose were present in small amounts.

51 A375-P cells, Con A binds to long, branched mannose and glucose types of oligosaccharides.

52 Mannose and glycocholate were associated with cardiovasc

53 TB-mediated delivery was independent of high-mannose and mannose-6-phosphate receptors, which are exp

54 te and alanine and reduced concentrations of mannose and urea were discriminatory for the presentatio

55 lc glycan as its 1,3 branch containing three mannoses and one terminal glucose.

56 inactive state when not bound to its target mannose, and an engineered activated variant that is alw

57 Paucimannosidic, high-mannose, and complex type glycans were identified and th

58 rivatized hexoses, d-glucose, d-galactose, d-mannose, and d-fructose, using only mass spectrometry wi

59 of four monosaccharides: maltose, D-xylose, mannose, and D-fructose.

60 C-glycopyranosyl aldehydes from D-glucose, D-mannose, and D-galactose.

61 ) and Glu(268), hydrogen bond to O1 of alpha-mannose, and either of these residues may function as th

62 N-acetylneuraminic acid (Neu5Ac), galactose, mannose, and fucose) and significantly (p < 0.05) alter

63 ree biologically important hexoses (glucose, mannose, and galactose).

64 ransferring three major types (complex, high-mannose, and hybrid type) of N-glycans for antibody glyc

65 ion of IFN-gamma on stimulation of dectin-1, mannose, and Toll-like receptors with Candida albicans a

66 residues that interact with the active site mannose are conserved in both GH130 mannoside phosphoryl

67 lose, d-allose, d-gulose, d-galactose, and l-mannose are delineated, and for all eight enantiomeric p

68 torsion angles between the two reducing-end mannoses are different from the free trisaccharide.

69 t the attachment of a GlcNAc on the alpha1,3 mannose arm of N-glycan is essential for FUT8-catalyzed

70 The application of d-mannose as a multipurpose building block from the chiral

71 l limitation and the alternate carbon source mannose as two environmental indicators likely to be enc

72 g lectin and impaired mannose-binding lectin-mannose-associated serine protease (MBL-MASP) functional

73 Mannose-binding lectin, together with mannose-associated serine proteases, activates the lecti

74 ecificity, and reveal that the presence of d-mannose at the +1 subsite renders the acid catalyst less

75 residues long) containing an alpha1-6-linked mannose backbone with greatly reduced alpha1-2-mannose s

76 Mannose-based ligands were also able to downregulate IL-

77 Alternatively, protein O-linked mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMG

78 at is caused by loss of an enzyme (protein O-mannose beta-1,2-N-acetylglucosaminyltransferase 1) that

79 zyme elongating O-Man glycans, the protein O-mannose beta-1,2-N-acetylglucosaminyltransferase, POMGnT

80 Protein O-linked mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMG

81 thmic range of detection (i.e., 3-7 for pili-mannose binding and 2-8 for Con A mediated binding), hig

82 CM) transducers and by using the direct pili-mannose binding as well as Concanavalin A (Con A) mediat

83 pulmonary and circulating opsonins, SP-D and mannose binding lectin 2, respectively.

84 A (Con A) mediated lipopolysaccharides (LPS)-mannose binding.

85 of UPEC to host cells is mediated by FimH, a mannose-binding adhesin at the tip of bacterial type 1 p

86 proteins via Fe3(+)-DOPA complexes, and the mannose-binding domain interacts with the soft tissue an

87 dihydroxyphenylalanine (DOPA)-containing and mannose-binding domains has been characterized from Atri

88 novel mouse that expresses functional human mannose-binding lectin (MBL) 2 under the control of Mbl1

89 with an overall structure similar to C1q and mannose-binding lectin (MBL) participate in microbe infe

90 The mannose-binding lectin (MBL) pathway of the complement c

91 We investigated the binding of the PRMs mannose-binding lectin (MBL), ficolin-1, ficolin-2, and

92 ads coated with an engineered human opsonin--mannose-binding lectin (MBL)--that captures a broad rang

93 allenged when it was shown that mice lacking mannose-binding lectin (MBL)-associated serine protease-

94 immunity to Giardia using mice deficient in mannose-binding lectin (Mbl2) or complement factor 3a re

95 and regulated complement activation through mannose-binding lectin 2.

96 levels of mannose-binding lectin and C1q-C4 were measured to exami

97 codon 52 was associated with a low level of mannose-binding lectin and impaired mannose-binding lect

98 Using anti-human mannose-binding lectin antibody, we evaluated mannose-bi

99 Mannose-binding lectin deficiency (defined as a mannose-

100 An association between mannose-binding lectin deficiency and anti-Saccharomyces

101 annose-binding lectin antibody, we evaluated mannose-binding lectin expression in tissue samples from

102 um concentrations of mannose-binding lectin, mannose-binding lectin functional activity, MBL2 and NOD

103 nose-binding lectin deficiency (defined as a mannose-binding lectin level of <500 ng/mL) did not infl

104 No associations between mannose-binding lectin or Ficolin-1 and graft loss were

105 Mannose-binding lectin protein is the activator of the l

106 Deposits of C4d, mannose-binding lectin, C1q, IgM, and C5b-9 were scored

107 The labels were recognized by the mannose-binding lectin, Con A, and the biotin-binding pr

108 Mannose-binding lectin, Ficolin-1, and Ficolin-3 were me

109 ent pathways due to efficient degradation of mannose-binding lectin, ficolin-2, ficolin-3, and C4, wh

110 relationship between serum concentrations of mannose-binding lectin, mannose-binding lectin functiona

111 imannosidic proteins displayed affinities to mannose-binding lectin, suggesting immune-related functi

112 Mannose-binding lectin, together with mannose-associated

113 The serum of mannose-binding lectin-associated serine protease (MASP)

114 level of mannose-binding lectin and impaired mannose-binding lectin-mannose-associated serine proteas

115 Binding of NS1 to MBL protects DENV against mannose-binding lectin-mediated neutralization by the le

116 ding protein, as well as to a novel partner, mannose-binding lectin.

117 age receptor with collagenous structure) and mannose-binding leptin expression.

118 To elucidate the mannose-binding receptor that retains tilmanocept in thi

119 arboring a deletion of the gene encoding the mannose-binding type 1 pilus tip protein FimH demonstrat

120 crystal structure of BT3780 in complex with mannose bound in the -1 and +1 subsites showed that a pa

121 The route features a mannose building block with C-5 ester enforcing a beta-l

122 rimarily responsible for QS induction due to mannose, but each sensory system induced Rgg-SHP signali

123 rides that are subsequently depolymerized to mannose by the action of periplasmic enzymes.

124 The removal of the alpha-1,3-mannose by the alpha-mannosidase NixK (GH92) is a prereq

125 sor surface, especially when compared to the mannose- (C6-MAN) and ethylene-glycol-terminated (C6-EG)

126 We tested whether mannose-capped lipoarabinomannan (LAM)-induced inhibitio

127 oach for preparing compact, dense polyvalent mannose-capped quantum dots (QDs) has been developed.

128 Thus, both MPI activity and exogenous mannose concentration determine the metabolic flux into

129 s with these receptors are influenced by the mannose-containing Fc.

130 A high mannose-containing glycan was attached to Asn614 in the

131 er, wild-type Fbs1 preferentially binds high-mannose-containing glycans.

132 ocept or [(99m)Tc]-tilmanocept) is the first mannose-containing, receptor-directed, radiolabeled trac

133 host glycans by increasing fucosylation and mannose content, while decreasing sialylation.

134 eductive aminocyclization/lactamization of d-mannose/D-glucose derived C5-gamma-azido esters as a key

135 the trypanosome de novo pathway enzymes GDP-mannose dehydratase (GMD) and GDP-fucose synthetase (GME

136 multivalent systems displaying a protected d-mannose derivative or an iminosugar by way of CuAAC.

137 mannose synthase (DPMS), which generates the mannose donor for glycosylation in the endoplasmic retic

138 KO of two isoforms of GDP-D-mannose epimerase (OsGME) reduced the foliar AsA level b

139 Glucose and mannose esterified at O-6 by a synthetic alpha-ramified

140 ar-containing [60]fullerene units (total 120 mannoses)-exhibit an outstanding antiviral activity with

141 mannosidase could be known to hydrolyze beta-mannose, for example, but from what is presently hard to

142 ctose, arabinose, glucose, rhamnose, xylose, mannose, fructose and ribose) plus inositol as internal

143 abinose, glucose, sucrose, rhamnose, xylose, mannose, fructose, and ribose were quantified in packed

144 Arabinose, xylose, mannose, galactose and glucose were the main sugar const

145 ery specific spectral patterns for fructose, mannose, glucose, and galactose.

146 Composed of a pentameric repeating unit of mannose, glucose, and rhamnose, the biosynthesis of Psl

147 f typical of C-type animal lectins that bind mannose, glucose, or GlcNAc, yet it has been reported th

148 que pattern of carbohydrates, with many high-mannose glycans and also, in some places, complex glycan

149 ngly, bnAbs that bind to the cluster of high-mannose glycans on the HIV envelope glycoprotein, gp120,

150 nd reveals an unexpected orientation of high-mannose glycans on the human Fc that provides greater ac

151 e many of the sites contain exclusively high-mannose glycans, others retain complex glycans, resultin

152 ENV-infected insect cells contains only high mannose glycans.

153 ancy and the relative contribution from high mannose glycans.

154 Manalpha units on the D1 and D3 arms of high mannose glycans.

155 coprotein is extensively decorated with high-mannose glycans.

156 Nine metabolites, including cotinine, mannose, glycocholate, pregnendiol disulfate, alpha-hydr

157 High-mannose glycoform preferentially samples conformations t

158 of production of fully core-fucosylated high-mannose glycoforms.

159 st (presently horseradish peroxidase, HRP, a mannose glycoprotein) as the biochemical target for Arti

160 on protein-1 also exclusively displayed high-mannose glycosylation at Asn-137.

161 s, including homo- and mixed N-glycans (high-mannose, hybrid and complex types) that were prepared by

162 y glycans, varying in the proportion of high-mannose/hybrid and complex-type glycans.

163 ites that are unoccupied or occupied by high-mannose/hybrid or complex-type glycans.

164 s of a series of sequentially truncated high-mannose IgG1 Fc glycoforms, we found that the C'E loop a

165 th glucose, N-acetylglucosamine (GlcNAc) and mannose in between.

166 Sugar analysis indicated the presence of mannose in each of the oligomers.

167 ty are well characterized, the function of D-mannose in T cell immune responses remains unknown.

168 locus, encoded by manLMN, was expressed as a mannose-inducible operon that exhibited the most influen

169 e we elucidate further the structure of an O-mannose-initiated glycan on alpha-dystroglycan that is r

170 th involved C-type lectin receptors, because mannose injection decreased arginase activity induction

171 nd more intimately with its two reducing-end mannoses into the domain A binding site of CV-N than wit

172 beta-Mannose is a major component of plant structural polysac

173 allography and mutagenesis studies show that mannose is ligated to the conserved Ca(2+) in the primar

174 -glycan to expose a terminal alpha1,6-linked mannose is necessary for their degradation via ERAD, but

175 y and that affinity was greatly enhanced for mannose-linked alpha1-2 or alpha1-4 to a second mannose

176 led to the identification of several novel O-mannose-linked glycan structures, including sulfo-N-acet

177 tions in PMM activity, guanosine diphosphate mannose, lipid-linked oligosaccharide precursor and tota

178 Mass spectroscopy of hexa-Fc reveals high-mannose, low-sialic acid content, suggesting that intera

179 phiphilic Janus glycodendrimers (GDs) with d-mannose (Man) headgroups, a known routing signal for lec

180 Mannose (Man)- and galactose (Gal)-conjugated silica nan

181 Starting from concanavalin A (ConA), a mannose (Man)-binding protein, as a bait, we narrowed a

182 he CRD in complex with a mammalian-type high-mannose Man9GlcNAc2 oligosaccharide exhibited interactio

183 unrecognized immunoregulatory function of D-mannose may have clinical applications for immunopatholo

184 s on the influence of spacer length (between mannose-mimicking headgroups and quaternary nitrogen cen

185 liposomes of cationic amphiphiles containing mannose-mimicking shikimoyl headgroup are promising DNA

186 We have previously developed a potent mannose-modified lipid calcium phosphate (LCP) nanoparti

187 PslG formed a complex with two mannose monosaccharides in this groove, consistent with

188 at the cadherin superfamily carries O-linked mannose (O-Man) glycans at highly conserved residues in

189 rfamily of adhesion molecules carry O-linked mannose (O-Man) glycans at highly conserved sites locali

190 low for identification of the human O-linked mannose (O-Man) glycoproteome and used this to identify

191 Endo H was used to collapse high mannose oligosaccharides to a single peak of GlcNAc for

192 xture of afucosylated, fucosylated, and high mannose oligosaccharides was separated in the range of 1

193 lation acceptor sites harboring unusual high-mannose oligosaccharides.

194 und to a fucose mimetic; that is, a terminal mannose on an N-glycan attached to a symmetry-related mo

195 example, the type 1 pilus adhesin FimH binds mannose on the bladder surface, and mediates colonizatio

196 N-glycopeptide containing two GlcNAcs, three mannoses, one fucose, and one xylose (N2M3FX) as a subst

197 The Con A - mannose (or glucose) type glycans present on WM35 cell s

198 s mimicking the evolution of the entire high-mannose patch and promoting maturation of multiple diver

199 that differ in their recognition of the high-mannose patch and show that different immunogens may be

200 These results support the intrinsic mannose patch as a stable target for vaccine design.

201 effect on the overall size of the intrinsic mannose patch but leads to changes in the processing of

202 By analyzing the intrinsic mannose patch from a panel of recombinant CAP256 gp120s

203 CCR5 co-receptor binding site, with the high-mannose patch glycans serving to camouflage it from most

204 oth (324)GDIR(327) peptide residues and high-mannose patch glycans, which enabled broad reactivity ag

205 lopment of a bnAb lineage targeting the high-mannose patch in an HIV-1 subtype-C-infected donor from

206 quency over the course of HIV infection, the mannose patch is a conserved feature throughout, making

207 uch antibody, PGT135, contacts the intrinsic mannose patch of gp120 at the Asn332, Asn392, and Asn386

208 The high-mannose patch of human immunodeficiency virus (HIV) enve

209 The high-mannose patch on HIV Env is a preferred target for broad

210 The high-mannose patch on the HIV-1 envelope (Env) glycoprotein i

211 The persistence of the intrinsic mannose patch over the course of HIV infection further h

212 and positioning, we show that the intrinsic mannose patch persists throughout the course of HIV infe

213 in the formation of this so-called intrinsic mannose patch.

214 age, in which all members recognize the high-mannose patch.

215 at forms a localized subdomain of the native mannose patch.

216 uncover a previously unappreciated role for Mannose phosphate isomerase (MPI) as a metabolic enzyme

217 CIGB-EPO showed the greatest variety of high-mannose-phosphate structures.

218 not affect the catalytic activity but impair mannose phosphorylation of certain lysosomal hydrolases.

219 mutations in PMM2 that limit availability of mannose precursors required for protein N-glycosylation.

220 rophosphorylase, SVEN_3972 is an unusual ITP-mannose pyrophosphorylase, and SVEN_2781 is a pyrophosph

221 eath ligand-1 (PD-L1), Mac-2, and macrophage mannose receptor (CD206) and producing Klf4, Il10, Retnl

222 e activation including arginase-1 (ARG1) and mannose receptor (CD206).

223 pressing the multi-ligand endocytic receptor mannose receptor (CD206/MRC1) contribute to tumor immuno

224 The mannose receptor (ManR, Mrc1) and asialoglycoprotein rec

225 sdAbs) specifically targeting the macrophage mannose receptor (MMR), which has been identified as an

226 We investigated how innate sensing by the mannose receptor (MR) influences the development of anti

227 The mannose receptor (MR) is an endocytic receptor involved

228 MSCs also expressed mannose receptor (MR) that was found to endocytose rhoda

229 -derived macrophages (BMDMs) in vitro and by mannose receptor (MR)(hi) dermal macrophages in vivo com

230 In particular, mannose receptor (MR), through modulation of Toll-like r

231 at have high expression of the C-type lectin mannose receptor (MR; CD206).

232 abbing non integrin (DC-SIGN) and macrophage mannose receptor 1 (MMR-1).

233 hese include the antiinflammatory macrophage mannose receptor and arginase-1.

234 inity for both the insulin receptor (IR) and mannose receptor C-type 1 (MR), which functions to clear

235 ferator-activated receptor gamma (PPARG) and mannose receptor C-type 1 (MRC1), suggesting that PRMT1

236 he parasite load was reduced in mice lacking mannose receptor C-type 1.

237 human urine: cadherin 11 (CDH11), macrophage mannose receptor C1 (MRC1), and phospholipid transfer pr

238 ipase A2 receptor (PLA2R) is a member of the mannose receptor family found in podocytes in human kidn

239 Mannose receptor knockout (MR(-/-)) mice lack the abilit

240 manner, which can be blocked by injection of mannose receptor ligands.

241 CD68 (macrophage marker), M2 markers (CD206 (mannose receptor) and CD163 (scavenger receptor)), secre

242 resolution of inflammation, Dectin-1, CD206 (mannose receptor), and IL-4R.

243 ll receptor, integrin alphaM, and macrophage mannose receptor, are engaged in N-glycan ligand recogni

244 lecule-3 grabbing non-integrin (DC-SIGN) and mannose receptor, bound to FL surface immunoglobulin (sI

245 macrophages expressing arginase 1 (ARG1) and mannose receptor, C type 1 (MRC1).

246 egfp)(y251) transgenic zebrafish that uses a mannose receptor, C type 1 (mrc1a) promoter to drive str

247 ss several cell surface receptors (e.g., the mannose receptor, MR) that may serve as drug delivery ce

248 ently than N or P by mechanisms depending on mannose receptor- and dendritic cell-specific intercellu

249 sh-a2 tumors showed a reduced expression of mannose receptor-1 (CD206), interleukin-10, transforming

250 The mannose receptor-mediated enhanced cell uptake and high

251 an alternative phenotype being both CD68 and mannose receptor-positive, expressing carbonic anhydrase

252 brin or the endocytic collagen receptor, the mannose receptor.

253 of trophic forms were not due to ligation of mannose receptor.

254 een after infection and expressed macrophage mannose receptors, arginase-1 activity, and IL-10.

255 termini of the glycan, with the reducing-end mannose residue ligated to Ca(2+) in a primary binding s

256 ry binding site and the nonreducing terminal mannose residue occupying an adjacent secondary site.

257 nose-linked alpha1-2 or alpha1-4 to a second mannose residue.

258 alpha-(1-->2)- and two alpha-(1-->3)-linked mannose residues and is extended on a polyisoprenoid lip

259 can chains to remove all glucose and several mannose residues before extension into complex-type stru

260 ely that the two enzymes target the beta-1,2-mannose residues that cap the glycan produced by Candida

261 ble for cleavage of terminal alpha1,2-linked mannose residues to produce uniquely trimmed oligomannos

262 polymer comprising only alpha-(1-->2)-linked mannose residues.

263 Mannose-resistant Klebsiella-like (Mrk) hemagglutinins a

264 ase, which is required for urolithiasis, and mannose-resistantProteus-like fimbriae.

265 ified: 4 monosaccharides (glucose, fructose, mannose, rhamnose), 11 disaccharides (sucrose, trehalose

266 We show that both mutant proteins are mannose-rich glycosylated proteins that are not capable

267 from palmitoyl-CoA to the 6-position of the mannose ring linked to 2-position of inositol in PIM1/PI

268 we show that supraphysiological levels of D-mannose safely achievable by drinking-water supplementat

269 ator) and mshA (the 11th gene of the 16-gene mannose-sensitive hemagglutinin (MSHA) type IV pilus ope

270 he wild type, due to increased expression of mannose-sensitive type 1 pili.

271 In the mannose series the cyclization reaction employed as cloc

272 f glycan structural variants, including high mannose, sialylated, and terminal galactosylated species

273 nnose backbone with greatly reduced alpha1-2-mannose side chains and no arabinose caps.

274 We find that mannose spacing and valency dictate whether glycopeptide

275 Importantly, components of the mannose-specific EII also acted to prevent the early ons

276 The mannose-specific EII locus, encoded by manLMN, was expre

277 Here, we show that mannose-specific lectins, TIM-1 and Axl augment entry in

278 ich create potential novel binding sites for mannose-specific lectins.

279 In vitro, D-mannose stimulated Treg cell differentiation in human an

280 an-structure dependent and glycans with core mannose structures overwhelmingly lead to the generation

281 heavily glycosylated and bears numerous high mannose sugars.

282 sferases (PI-GTs) include dolichol phosphate mannose synthase (DPMS), which generates the mannose don

283 The introduced glycans carry mannose termini, which create potential novel binding si

284 There are residues of mannose, the arabinose, pyranose predominantly, is termi

285 of carbohydrates; a preferential binding of mannose toward glucose was observed, and good diastereos

286 ent the crystal structure of an NST, the GDP-mannose transporter Vrg4, in both the substrate-free and

287 ucing pathology due to loss of the Golgi GDP mannose transporter.

288 ycan substrates determines the efficiency of mannose-trimming reactions that control the conversion t

289 ur study we have compared the recognition of mannose type glycans in melanocytes (HEMa-LP) and melano

290 High-mannose-type glycans (HMTGs) decorating viral spike prot

291 The dense patch of high-mannose-type glycans surrounding the N332 glycan on the

292 show that ionizing radiation increases high mannose-type N-glycans and decreases glycosaminoglycans.

293 ide HMTG mimetics with systematically varied mannose valency and spacing.

294 Tuning the QD surface mannose valency reveals that DC-SIGN binds more efficien

295 of PslG (PslG(31-442)) and its complex with mannose were determined to 2.0 and 1.9 A resolution, res

296 accharides consist of galactose, glucose and mannose whereas the acidic polysaccharides contain fucos

297 PIGG is the enzyme that modifies the second mannose with ethanolamine phosphate, which is removed so

298 with predominance of glucose, galactose and mannose with no uronic acids detection; Flavourzyme extr

299 where loop 83-89 closes to engage Ca(2+) and mannose without triggering allostery that opens the lect

300 inose, glucose, galacturonic acid, rhamnose, mannose, xylose and traces of glucuronic acid.