ライフサイエンスコーパス: mannosidase II

1 ne its relationship to mammalian Golgi alpha-mannosidase II.

2 localized with the medial-Golgi marker alpha-mannosidase II.

3 emical similarities to mammalian Golgi alpha-mannosidase II.

4 the Sf9 enzyme is distinct from Golgi alpha-mannosidase II.

5 es originating from the Golgi and containing mannosidase II.

6 NBCCV was found to be colocalized with alpha-mannosidase II, a marker for the Golgi complex.

7 ndoplasmic reticulum, as well as that due to mannosidase II, a marker for the trans-Golgi network.

8 noprecipitate betaCOP, Golgi 58K protein, or mannosidase II, all Golgi-resident proteins.

9 When coexpressed with alpha-mannosidase II, alpha-mannosidase IIx colocalizes with a

10 Alpha-mannosidase-II (alphaM-II) catalyzes the first committed

11 Alpha-mannosidase-II (alphaM-II) deficiency diminishes complex

12 development consistent with increasing alpha-mannosidase II and core fucosyl-transferase enzyme activ

13 cDNA encoding a protein homologous to alpha-mannosidase II and designated it alpha-mannosidase IIx.

14 Mannosidase II and giantin were observed to colocalize w

15 ra and antisera against known Golgi markers (mannosidase-II and furin) revealed that the staining of

16 -GFP fusion colocalized with a Golgi marker, mannosidase II, and retained catalytic activity compared

17 Swainsonine, an inhibitor of Golgi alpha-mannosidase II, blocked beta1,6GlcNAc N-glycan expressio

18 e associated with the Golgi apparatus marker mannosidase II but not with markers to early endosomes (

19 icular stomatitis virus (VSV)-G protein to a mannosidase II-containing Golgi compartment.

20 d for the delivery of a cargo protein to the mannosidase II-containing Golgi compartment.

21 alpha-Mannosidase II-deficient autoimmune disease is due to an

22 reen et al. now show that mice lacking alpha-mannosidase II develop an autoimmune disease similar to

23 nnose trimming enzyme drosophila Golgi alpha-mannosidase II (dGMII) complexed with the inhibitors man

24 characterized included inserts in the alpha-mannosidase II (dGMII), ash1, and pumilio genes.

25 of the RER (ribophorin I) and GA (p58, alpha-mannosidase II, galactosyltransferase, and TGN38/41).

26 Golgi alpha-mannosidase II (GMII), a member of glycoside hydrolase f

27 aminyltransferase I, Arabidopsis Golgi alpha-mannosidase II (GMII), and Arabidopsis beta1,2-xylosyltr

28 Inhibition of Golgi alpha-mannosidase II (GMII), which acts late in the N-glycan p

29 In contrast, rab6 and alpha-mannosidase II, Golgi marker proteins, appear unchanged.

30 tegral membrane Golgi proteins called GEARs (mannosidase II, GOS-28, GS15, GPP130, CASP, giantin, and

31 alpha-mannosidase IIx colocalizes with alpha-mannosidase II in COS cells.

32 The functional role of ER mannosidase II in glycoprotein quality control is discus

33 olgi transport of Rh1, downstream from alpha-mannosidase-II in the medial- Golgi.

34 Golgi alpha-mannosidase II is an enzyme that processes the intermedi

35 nto small punctate structures at a time when mannosidase II is still largely localized to Golgi struc

36 nd cosedimented with the Golgi marker, alpha-mannosidase II (Man II).

37 GalT was compared with transfected rat alpha-mannosidase II (medial-Golgi, polyclonal antibody).

38 alpha-Mannosidase II (MII) is a key enzyme converting precurso

39 1,2-mannosidase I (MIa,b,c), MGAT1, alpha1,2-mannosidase II (MII, IIx), and MGAT2.

40 several Golgi and vesicle markers, including mannosidase II, p58, trans-Golgi network (TGN)38, and be

41 g kinetics was seen with the HeLa GalT/alpha-mannosidase II pairing.

42 ed oligosaccharides by endoplasmic reticulum mannosidase II partitions variant PI Z away from the con

43 We report recruitment of mannosidase-II-positive Golgi-derived vesicles during up

44 Brefeldin A treatment inhibited mannosidase-II recruitment and phagocytic uptake of seru

45 on is temporally and spatially distinct from mannosidase II relocation and that FTCD provides a novel

46 its redistribution is distinct from that of mannosidase II relocation.

47 onsisting of the first 117 residues of alpha-mannosidase II tagged with a fluorescent protein and a t

48 Swainsonine, an inhibitor of Golgi alpha-mannosidase II that causes abnormal N-glycosylation, str

49 Mechanistically, recruitment of mannosidase-II vesicles during phagocytic uptake require

50 The recruitment of mannosidase-II vesicles was an early event mediated by f

51 taining pattern was similar to that of alpha-mannosidase II which is a known resident enzyme of the G

52 at mutation of a single gene, encoding alpha-mannosidase II, which regulates the hybrid to complex br