ライフサイエンスコーパス: margin

1 inoma, 12 weeks) or excisional surgery (4-mm margin).

2 of 90% CI, 26.1%, within the predefined 37% margin).

3 %), which was within the 4.0% noninferiority margin.

4 antle in this section of the Central America margin.

5 CI exceeded the prespecified noninferiority margin.

6 nly within approximately 30 mum of the wound margin.

7 esigned as a noninferiority study with a 15% margin.

8 olute difference of 7% as the noninferiority margin.

9 ere wind has been commonly dispatched on the margin.

10 ground glass component and the type of tumor margin.

11 ical guidelines endorsing a minimal negative margin.

12 trong sexual selection at the northern range margin.

13 ive oxygenation of the extensive continental margin.

14 rs across a cell population by a significant margin.

15 more specific known associations by a large margin.

16 sp4 within the first two cell tiers from the margin.

17 geon attitudes toward an adequate lumpectomy margin.

18 larity with frayed appearance at the capsule margin.

19 hantom sample that simulated positive tumour margins.

20 abitat, olive groves, wheat fields and field margins.

21 nts require further surgery to achieve clear margins.

22 es in shallow water of the Brazilian-Angolan margins.

23 ation between date of treatment and positive margins.

24 alf that proved to be melanoma with positive margins.

25 e conservation value of populations at range margins.

26 M and LMM and can be used to delineate their margins.

27 ients with node-positive disease or positive margins.

28 ers may result in reduced positive resection margins.

29 ior of the sedimentary prism in accretionary margins.

30 ccurate presurgical assessment of LM and LMM margins.

31 gular nodules or nodules with poorly defined margins.

32 device also successfully identified positive margins.

33 as evidence of crystallization along conduit margins.

34 re calculated and compared with the surgical margins.

35 ifference 10.2% vs specified non-inferiority margin 10%).

36 ing of the primary end point (noninferiority margin, -10 percentage points).

37 lticenter, open-label, noninferiority trial (margin 12%).

38 dominant site of recurrence was at the tumor margin (12 patients, 57.1%).

39 ntrations during weeks 20-27 (noninferiority margin, 12.0%).

40 ), but a lower re-excision rate for positive margins (13/119 = 10.9% vs 32/116 = 27.6%, P < 0.01).

41 esidual microscopic disease at the resection margin, (2) intraparenchymal spread of neoplastic cells,

42 at MR imaging compared with spiculated mass margins (24.0 vs 17.6; P < .02).

43 dible interval -5.5 to 0.1], non-inferiority margin 3.85%, n=2208).

44 surgeons were surveyed regarding lumpectomy margins; 342 (70%) responded completely.

45 nd secondary hypotheses were noninferiority (margin: 5 letters at a 1-sided alpha level 0.1) in best-

46 , such as fast parasite killing, good safety margin, a potentially novel mode of action and a distinc

47 d [Si(OH)4] on the west Antarctica Peninsula margin, a region in which the modern phytoplankton envir

48 Using the same targeting margins, ablation lesion size notably increased with the

49 th positive compared with negative resection margins after abdominoperineal excision [hazard ratio (H

50 ent mucosa (3 cm from the macroscopic tumour margin, AG/IM GC+).

51 ant effect of negative microscopic resection margins (AHR, 0.9; 95% CI, 0.4 to 2.2; P = 0.86).

52 ] age, 59 [21] years), a total of 166 eyelid margin and 129 conjunctival lesions were included in the

53 5%), meeting the prespecified noninferiority margin and allowing for statistical noninferiority of er

54 icroscopy (IVCM) for the diagnosis of eyelid margin and conjunctival tumors.

55 fore surgery and is associated with positive margin and mastectomy rates that are low irrespective of

56 nal imaging, and surgical outcomes (positive margin and mastectomy rates) were investigated.

57 Information about positive resection margins and subsequent treatment failure was pooled usin

58 ints were the proportion of positive section margins and the occurrence of treatment failure associat

59 with rigorous assessment of circumferential margins and the R0 definition with a 1 mm free margin we

60 velocity control the architecture of rifted margins and their temporal evolution.

61 showing a loss of the proteins at the wound margins and/or in the regenerating epidermis.

62 readmission, </=3.1% for positive resection margins, and >/=23 for lymph node yield.

63 se, positive lymph nodes, positive resection margins, and extended cholecystectomy.

64 improve diagnostic accuracy, identify tumor margins, and stage early cancers.

65 ents had >/= pT3a disease, positive surgical margins, and/or pathologic lymph node invasion.

66 For example, nodule attenuation and margins are associated with the late cell-cycle genes, a

67 has favorable recurrence rates when melanoma margins are difficult to assess, and recurrence rates ar

68 Unfortunately, negative margins are not always surgically achievable due to tumo

69 ere significantly more likely to report this margin as adequate (85%; n = 105) compared with those tr

70 diagnostic accuracy of intraoperative breast margin assessment (IMA) techniques against which the per

71 l of this device for automated breast tumour margin assessment to minimise repeat invasive surgeries.

72 ls into question the reliability of negative margin assessment.

73 LI a promising technology for intraoperative margin assessment.

74 east density, calcification morphology, mass margins at mammography and MR imaging, and nonmass enhan

75 was significantly higher for irregular mass margins at MR imaging compared with spiculated mass marg

76 to exclude a 2.5% increase [non-inferiority margin] at 5 years for each experimental group; non-infe

77 warming, with a retreat of the northern ice margin behind its present position in the mid Holocene a

78 on to reflect cooling of the magma reservoir margins below approximately 475 degrees C, accumulation

79 rrow therapeutic index, reflected in a small margin between a dose that achieves good glycemic contro

80 is strategy may provide a better therapeutic margin between antithrombotic and antihemostatic effects

81 n important macronutrient with a very narrow margin between essentiality and toxicity.

82 To compare the rate of positive resection margins between radioactive seed localization (RSL) and

83 resected tumor were found in one-half of the margin biopsy smears, even in cases where postoperative

84 rowing compartments: the retina, the ciliary margin (CM), and the retinal pigment epithelium (RPE).

85 y without any increase in positive resection margins compared with WGL.

86 articularly strict test: a priori defining a margin compatible with equivalence (g=0.25), using the t

87 hematoxylin-eosin-stained permanent section margin control commonly known as the square technique.

88 xcision with comprehensive permanent section margin control of melanomas arising in chronically sun-d

89 hematoxylin-eosin-stained permanent section margin control.

90 the impact of the circumferential resection margin (CRM) in esophageal cancer on survival and recurr

91 e rate of positive circumferential resection margin (CRM), defined as 1 mm or less from the closest t

92 ciated with excision of routine cavity shave margins (CSM) versus standard partial mastectomy (PM) in

93 ALC is involved in valve margin development and, thus, contributes to seed shatte

94 the 95% CI exceeded the 15% non-inferiority margin (difference 9.1%, 95% CI -5.6 to 23.8).

95 S (regarding location, morphologic features, margins, dimensions, and pattern) was compared with that

96 istopathology results, and mean radiance and margin distance were measured.

97 thosphere leads to the formation of distinct margin domains.

98 between the ocean and the West Greenland ice margin during the YD.

99 urgeon's ability to best determine resection margins during prostatectomy.

100 splenomegaly (>/=5 cm below the left costal margin), Eastern Cooperative Oncology Group performance

101 tions and coastal response along the Pacific margin, exposing many heavily populated regions to incre

102 The margin for optimizing polychemotherapy is wide, but a qu

103 kidney nephrons and relatively small safety margin for some surface waters may warrant a longer term

104 nts without NAT or VR; (2) R1-0 mm posterior-margin for the NAT group (P = 0.004).

105 To describe surgeons' approach to surgical margins for invasive breast cancer, and changes in postl

106 the utility of DESI-MS in assessing surgical margins for maximal safe tumor resection.

107 Human populations living close to forest margins fragmented and disturbed by deforestation may be

108 gnetic resonance imaging) showed a chance of margin-free (R0) resection of the primary tumor and at l

109 The mean (SD) margin from lesion to clearance for melanoma in situ was

110 d seventeen (75%) patients were allocated to margin group I, 32 (8%) to group II, and 73 (17%) to gro

111 The prognostic value of margin group status was confirmed on multivariate analys

112 Data were stratified by resection margin (group I: FS-R0 --> PS-R0; group II: FS-R1 --> PS

113 (ReRAM) device demonstrates improved readout margin (>2(9) word lines) suitable for x-point memory ar

114 Masses with indistinct margins had an average ODxRS of 31.3, which significantl

115 Furthermore, as Cordilleran-type margins have been common since the onset of modern plate

116 trative nature, difficulty in obtaining wide margins, high recurrence rates, acute and chronic surgic

117 ncreased productivity near the boreal forest margin in Alaska.

118 k predictors were (1) R1 <1.0 mm for the SMA-margin in specific subgroups (upfront pancreatectomy, N0

119 nique for intraoperative assessment of tumor margins in BCS.

120 G CLI for intraoperative assessment of tumor margins in BCS.

121 increased the detection of positive section margins in nonmelanoma skin cancer from 8.4% to 12.8%.

122 ) regions have the narrowest thermal safety margins in upper canopy leaves; these regions are at the

123 Certain transcripts are enriched in margins, including those of CINCINNATA-like TCPs (TEOSIN

124 more accurate techniques to assess resection margins intraoperatively, because on average 20% of pati

125 The distal resection margin involvement (RR, 1.12; 95% CI, 0.34-3.67; P = .86

126 argin), R1 (<1 mm clearance), and R1 (direct margin involvement) status and associated survival were

127 ltration of the proximal or distal resection margin is associated with poor survival and higher recur

128 S, unlike WLE, the entire cutaneous surgical margin is evaluated intraoperatively for tumor cells.

129 SUMMARY OF BACKGROUND DATA: Resection margin is important to guide therapy and to evaluate pat

130 definition of R0 requiring a 1 mm tumor-free margin is not commonly accepted.

131 e epithelial NADPH oxidase Duox at the wound margin is required early during this response.

132 itial lumpectomy to obtain more widely clear margins is common and may lead to mastectomy.

133 inical attachment level (rCAL), and gingival margin level (GML) at baseline and 9 months after surger

134 Rifted margins mark a transition from continents to oceans and

135 6; P = .91), the mean distance to the distal margin (mean difference, 0.01 cm; 95% CI, -0.12 to 0.15

136 m; P = .87), and the mean distance to radial margins (mean difference, -0.67 mm; 95% CI, -2.16 to 0.8

137 In addition, the margins measured in millimeters estimated for tumor clea

138 Patients who underwent a margin-negative (R0) resection, and who had previously u

139 chemotherapy for AS (58% vs 22%, P < 0.01), margin-negative resection (100% vs 73%, P < 0.01), recon

140 sisted in a subset analysis of patients with margin-negative resection (HR, 0.97; 95% CI, 0.66-1.45;

141 is minimized and survival often prolonged if margin-negative resection can be accomplished during can

142 alysis demonstrated superior circumferential margin negativity rates with LP compared with OP (odds r

143 The noninferiority margin (NIm) for the between-group difference was set at

144 owing a 2014 consensus statement endorsing a margin of "no ink on tumor." This was a population-based

145 concluded if the entire 95% CI was within a margin of -12% to 12%.

146 orithm), with a prespecified non-inferiority margin of -12%.

147 ps was more than the prespecified acceptable margin of -5 letters at both 12 weeks and 52 weeks.

148 We used Bayesian analytical methods (with a margin of 0.07) to evaluate the noninferiority of TAVR a

149 ival with a noninferiority hazard ratio (HR) margin of 1.3.

150 vity (P > .99) using the predefined absolute margin of 10%.

151 al was powered to show noninferiority with a margin of 15 percentage points.

152 the 95% CI was less than the non-inferiority margin of 15%.

153 cillin for 7 days was equivalent (similarity margin of 3%) to placebo in young infants with isolated

154 MANACH, within statistical variability, by a margin of 3%.

155 ided 95% CI, 2.1% [within the noninferiority margin of 3.0%]).

156 fell within the prespecified noninferiority margin of 3.2 percentage points.

157 A margin of 4.0% was defined for non-inferiority of the Mi

158 A noninferiority margin of 4.0% was selected to allow for no more than a

159 We used a non-inferiority margin of 4.5% (absolute difference between rivaroxaban

160 ofosbuvir-velpatasvir using a noninferiority margin of 5%.

161 orithm), with a prespecified non-inferiority margin of 8%.

162 orithm), with a prespecified non-inferiority margin of 8%.

163 SS were within the bounds of the equivalence margin of 80% and 125%.

164 axSS, with all CIs within the bioequivalence margin of 80-125%.

165 For safety, a noninferiority margin of a 3.0% absolute increase in MACEs within 6 wee

166 while to the south, the volcano lies on the margin of a broad conductive region in the deep crust.

167 A +/-0.75-diopter margin of equivalence for the treatment difference betwe

168 Losses close to the margin of error were observed for trace elements.

169 sures included compliance (ie, the mean [95% margin of error] number of meditation sessions that a pa

170 ion and were tested against a noninferiority margin of HR = 1.1.

171 Of 342 responding surgeons, 69% endorsed a margin of no ink on tumor to avoid reexcision in estroge

172 e than corticosteroids with a 37% acceptable margin of non-inferiority.

173 This northeastern margin of North America appears to have been populated m

174 At the southern margin of permafrost in North America, climate change ca

175 of pediatric CNV occurrence at the temporal margin of retinochoroidal and optic nerve colobomas clos

176 Margin of stability and base of support were evaluated w

177 and valley glaciers, along with the southern margin of the CIS, advanced into recently deglaciated re

178 all eyes, CNVs were located at the temporal margin of the coloboma closest to the macula.

179 ater end member originated along the western margin of the Labrador Sea, analogous to dense water for

180 d region with high mitotic activity near the margin of the segment addition zone is likely to have co

181 n experiencing recent growth at the northern margin of the Tibetan plateau.

182 In the southern margin of their range, populations of the common lizard

183 ctic-alpine or boreal plants at the southern margin of their ranges in the Rocky Mountains of Montana

184 de the interface between land and sea at the margin of woody plant distribution.

185 s on Raman Spectroscopy to assess the entire margins of a resected specimen within clinically feasibl

186 fall over the continent and up to 35% on the margins of East Antarctica, significantly affecting sate

187 teria had their measurements recorded at the margins of eligibility.

188 were found in 2 patients and occurred at the margins of EMPD, close to previous biopsy sites.

189 e Danian-Selandian boundary around the other margins of Greenland, including the North Sea, implying

190 currence, suggesting that tumor sizes at the margins of HCC transplant criteria may be subject to ina

191 ominated by V(IV) porphyrins except at outer margins of layers, where octahedrally coordinated V(III)

192 llary nodes (pN0-1), and minimum microscopic margins of non-cancerous tissue of 2 mm or more, were re

193 fusions showed that SLI1 is confined to the margins of sieve elements where it lines the parietal la

194 hydrates is pervasive across the continental margins of the Arctic Ocean.

195 lade, in particular in southern and northern margins of the current geographical distribution.

196 ly a strike-slip plate boundary, the faulted margins of the Gulf display largely dip-slip extensional

197 ding as microcalcifications at the resection margins of the lumpectomy specimens, but had negative mi

198 c diversity of peripheral populations at the margins of the species' range, particularly in face of c

199 sociated with the histological status of the margins of the tissue excised to treat cervical precance

200 ial occur as discontinuous patches along the margins of thermochemical piles and have asymmetrical cr

201 Margins of trans-Golgi cisternae accumulate the LM8 xylo

202 h was used to establish non-inferiority (15% margin) of ridinilazole versus vancomycin.

203 rough week 48; we tested non-inferiority (4% margin) of the study regimen versus the control regimen

204 at the role of the circumferential resection margin on survival and local recurrence after esophagect

205 CIN2+ is significantly greater with involved margins on excisional treatment; however, high-risk HPV

206 xerted in the South and Southwest Portuguese margins, on muddy and muddy-sand bottoms between 200 and

207 ed "Breast Cancer" AND "Intraoperative" AND "Margin." Only clinical studies with raw diagnostic accur

208 otal of 278 consecutive patients with eyelid margin or conjunctival lesions were included.

209 There were higher rates of clear surgical margins (OR: 1.64, 95%CI: 1.32 to 2.05, p < 0.00001) in

210 to the prostate but with a positive surgical margin) or T3 (with histologic extension beyond the pros

211 esence of precancerous tissue at the section margins, or post-treatment HPV testing are accurate pred

212 fell significantly below the noninferiority margin ( P < .001).

213 ed from the ODxRS of 18.5 for all other mass margins (P < .01).

214 Over the continental margins, persistent katabatic winds blow all year long a

215 ange is predicted to cause a decline in warm-margin plant populations, but this hypothesis has rarely

216 ses (7.4%; 95% CI: 2.4%, 18.1%) demonstrated margins positive for cancer that required re-excision.

217 higher stage disease (P < 0.001), but lower margin positivity (20.5% vs 25.9%, P = 0.01) and improve

218 ive complications, circumferential resection margin positivity (CRM+) and other pathological outcomes

219 plete radiation dose had a similar resection margin positivity (OR, 0.99; 95% CI, 0.72-1.35; P = .92)

220 ze and excise breast lesions with acceptable margin positivity and re-excision rates.

221 pite unfavorable effect on patient outcomes, margin positivity rate has not changed significantly ove

222 ssion methods were used to compare resection margin positivity, permanent colostomy rate, 30-day read

223 perative and oncologic outcomes encompassing margin positivity, permanent ostomy rate, postoperative

224 d could be predicted by the hydraulic safety margin, providing strong support for leaf vulnerability

225 The rates of R0 (>/=1 mm margin), R1 (<1 mm clearance), and R1 (direct margin inv

226 ) investigate the surgical outcome (positive margin rates and mastectomy rates) of women with breast

227 The positive resection margin rates for abdominoperineal excision were 14.7% an

228 ssion analysis to analyze positive resection margin rates reported in the literature.

229 A significant decrease in positive resection margin rates was identified over time for abdominoperine

230 tacks in the border cells have hypertrophied margins, reflecting elevated biosynthetic activity to pr

231 th positive compared with negative resection margins (relative risk 4.8, 95% CI 3.2-7.2).

232 in residual tumor at neurosurgical resection margins, representing the source of relapse in nearly al

233 reast conserving surgeries, efficient tumour margin resection is required for minimizing tumour recur

234 elt along the calving face, triggering rapid margin retreat and increased iceberg discharge.

235 bullitive methane seep field on the Svalbard margin reveal atmospheric CO2 uptake rates (-33,300 +/-

236 Ocean margin sediments have been considered as important sourc

237 ate convergence; lithospheric faults driving margin segmentation act as windows through which inherit

238 ed MSC were found to accumulate in the wound margins several days after i.v. administration.

239 ack of nodal involvement, and clear surgical margins, she met recommended MammoSite criteria, and she

240 d neck cancer (LAHNC) with negative surgical margins (SM negative) and no extracapsular extension (EC

241 -protocol analysis revealed no difference in margin status (P = 0.62).

242 The primary outcome was margin status after BCS.

243 The definitions for R0 and R1 margin status after resection for pancreatic cancer are

244 he aim of this study was to assess resection margin status and its impact on survival after abdominop

245 hereas pT stage, Gleason score, and surgical margin status did not.

246 udy was to assess the relevance of resection margin status for survival after resection of pancreatic

247 To assess the relevance of resection margin status for survival outcome after resection and a

248 Resection margin status influences survival and a multidisciplinar

249 or frozen section analysis to assess tumour margin status intraoperatively.

250 performed to assess the impact of resection margin status on survival, and a regression analysis to

251 e context of adjuvant therapy, the resection margin status remains an important independent determina

252 We estimated the accuracy of the margin status to predict occurrence of residual or recur

253 By multivariable analysis, margin status was confirmed to be independently associat

254 ing for age, sex, race, stage, surgery type, margin status, comorbidities, and use of chemotherapy.

255 ence of residual disease, T stage, resection margin status, lymph node involvement, and postoperative

256 T3/T4N0, pT3/T4Nx and pTanyN+), and surgical margin status.

257 dicts treatment failure more accurately than margin status.

258 For WLE-treated tumors, the surgical margin taken was greater for tumors that recurred compar

259 bution of the plough marks indicates calving-margin thicknesses equivalent to the threshold that is p

260 alth care organizations to enhance value and margin through principled and effective cost management.

261 o investigate the local recurrence rates and margin to clearance end points using staged excision wit

262 ted area being less available as an adaptive margin to hydrological stress.

263 rmed on 205 proteins isolated from the tumor margin, tumor bulk, and perinecrotic regions of 13 previ

264 linical diagnosis of conjunctival and eyelid margin tumors is challenging, and new noninvasive imagin

265 The specificity for malignant eyelid margin tumors was higher for IVCM than for slitlamp exam

266 Patients with positive margins, unknown estrogen receptor status, and comedo ne

267 97.5% CI lay on the positive side of the -7% margin, using a one-sided test done at the 2.5% signific

268 The noninferiority margin was 5 letters, and statistical testing for noninf

269 The prespecified equivalence margin was 7% or less.

270 The noninferiority margin was 7.5% (hazard ratio, < 1.32).

271 A 6.6% noninferiority margin was chosen.

272 Although margin was predictive of DSS, multifocality calls into q

273 The non-inferiority margin was prespecified as -5 Early Treatment Diabetic R

274 ose who received placebo; the noninferiority margin was set at 20% of the standard deviation of the s

275 The proportion of positive margins was 23.1% (95% CI 20.4-25.9) overall and varied

276 an (SD) area of surgical excision with clear margins was 7.74 (5.28) cm2.

277 of crustacean trawlers along the Portuguese margin, we have identified the most exploited areas and

278 he tumor and improved visualization of tumor margins, we developed new viral-based platforms with 2 s

279 ver, transitions to SC at the northern range margin were accompanied by loss of S-RNase, smaller flow

280 lignant tumors of the conjunctiva and eyelid margin were calculated using clinical examination with s

281 umor counts at the lower transplant criteria margin were corroborated by lower than expected HCC recu

282 rgins and the R0 definition with a 1 mm free margin were introduced into clinical routine in 2005.

283 le analysis, age, radicality of surgery, and margin were predictive of DSS.

284 Prespecified noninferiority margins were 1.5 (RMDQ) and 1.0 (pain).

285 r patient age and previous surgery, surgical margins were a mean of 0.76 mm (95% CI, 0.67-0.84 mm; P

286 All 15 assessable margins were clear on CLI and histopathology.

287 removed from the right upper outer quadrant, margins were free of tumor, and there was no angiolympha

288 Resection margins were free of tumor.

289 N2+ of 0.8%, whereas this risk was 3.7% when margins were free.

290 The margins were negative.

291 Here, resection margins were positive in 23 cases (11.8%) in the RSL gro

292 After the first reexcision, positive margins were still present in 97 patients (16.4%).

293 which persisted in small defined foci in the margins when the mitotic activity had already ceased in

294 rogenitors, while the cells further from the margin, which receive Nodal and/or Fgf signaling, are sp

295 s from close to the East Antarctic Ice-Sheet margin, which together suggest that volcanically-induced

296 reatment is surgical resection with negative margins, which corresponds to improved survival and a re

297 m has been advocated for the Central America margin while at other locations mass balance considerati

298 tomy specimens, but had negative microscopic margins, will be discussed.

299 high tumor cell percentage (TCP) at surgical margins with 93% sensitivity and 83% specificity.

300 biogeochemical fluxes at and near the ocean margins, with implications for coastal organisms and eco