ライフサイエンスコーパス: margination

1 1 cm), with higher hematocrit showing faster margination.

2 hat hematocrit plays a role in the degree of margination.

3 2 interactions in regulating lung neutrophil margination.

4 r n-3 fatty acids affect fasting and fed TRL margination.

5 al cell activation as evidenced by leukocyte margination.

6 antly altering blood neutrophil half-life or margination.

7 .58 vs. 3.4 +/- 0.20; p < 0.0001), chromatin margination (14.2 +/- 0.57 vs. 6.5 +/- 0.37; p < 0.0001)

8 Margination and adhesion should be independently address

9 l NPs in the flow play a dominant role in NP margination and cell interaction, compared to Brownian m

10 -3-positive neurons also exhibited chromatin margination and condensation, chromatin balls, and nucle

11 In this paper, we demonstrate that early margination and emigration of neutrophils originate in t

12 The roles of selectins in the pulmonary margination and emigration of neutrophils were investiga

13 fficacy because of their effects on particle margination and interactions with various cells in vivo.

14 red blood cell (RBC) interaction on platelet margination and near-wall dynamics in a shear flow.

15 models of whole blood to understand platelet margination and near-wall platelet dynamics.

16 ction was associated with reduced neutrophil margination and pulmonary myeloperoxidase activity.

17 es from 1 hour of reperfusion revealed dense margination and substantial emigration of neutrophils as

18 ocyte defects, such as decreased endothelial margination and tissue recruitment, are rate-limiting st

19 ctivated endothelial cells, mononuclear cell margination) and interstitial hemorrhage, but not the ex

20 ng (zeiosis), and chromatin condensation and margination, and decrease in cellular DNA content.

21 Sub-G1 fraction, chromatin margination, and phosphatidylserine exposure were eviden

22 Although particle adhesion and margination are related, adhesion also depends on other

23 tration distribution profile and observe its margination at 10%, 20%, and 30% red blood cell hematocr

24 nular, or smudgy chromatin without prominent margination at the nuclear membrane; they exhibited smal

25 ing (zeiosis) and chromatin condensation and margination, both of which are hallmarks of apoptosis.

26 e crucial role of the vessel geometry in the margination by calculations when the blood is seen as vi

27 tive particles can strongly accelerate their margination by moving against the flow direction: partic

28 ur results imply that a significantly faster margination can be achieved either technically by the ap

29 ate convective transport in the bloodstream, margination, cell adhesion, selective cellular uptake, a

30 imply alter leukocyte stiffness to fine tune margination/demargination and therefore leukocyte traffi

31 These simulations also confirm that margination from an initially uniform distribution of sp

32 Although margination has beenmodeled by numerical simulations and

33 Experimental results indicate that margination has largely occurred before particles travel

34 metal NPs likely results from their distinct margination in laminar blood flow, which opens up a new

35 selectively blocked IL-8-induced neutrophil margination in rabbits.

36 lular spaces with chromatin condensation and margination in the upper stratum spinosum in lesional sk

37 the first data demonstrating that neutrophil margination in uninfected pulmonary capillaries does not

38 is responsible for neutrophil chemotaxis and margination induced by IL-8.

39 The vessel-geometry-regulated margination is then confirmed by in vitro experiments in

40 Margination occurs when blood borne particles attach to

41 tures characteristic of apoptosis, including margination of chromatin and crenated nuclei of cells in

42 pleted preOLs included nuclear condensation, margination of chromatin, and mitochondrial swelling.

43 he H5N1 infection also resulted in prolonged margination of circulating T lymphocytes and notable apo

44 is marked by inflammatory immune responses, margination of leukocytes, and parasitized erythrocytes

45 Deliberate margination of lysosomes is associated with reduced acid

46 allograft recipients indicated perivascular margination of monocytes and neutrophils, vascular endot

47 s neutrophilia was associated with increased margination of neutrophils within pulmonary capillaries

48 apoptotic changes including condensation and margination of nuclear chromatin, DNA fragmentation, and

49 Here, we report the margination of stiffened RBCs in vivo, and reveal the cr

50 Margination of stiffened red blood cells has been implic

51 The LPL*GPIHBP1 complex is responsible for margination of triglyceride-rich lipoproteins along capi

52 The margination parameter, M, is defined as the total number

53 nent peritubular capillary inflammatory cell margination; patchy interstitial hemorrhage; interstitia

54 In this study, we quantified the margination propensity of particles of varying diameters

55 Most previous studies evaluated the margination propensity of these particles via an adhesio

56 Margination refers to the migration of particles toward

57 tudy was undertaken to determine whether TRL margination reflects in vivo LpL activity and whether n-

58 d through a multistep paradigm that includes margination, selectin-mediated rolling, beta 2 integrin-

59 fic in the lungs, particularly in neutrophil margination, sequestration, and emigration, using L-sele

60 sions, with a nuclear phenotype of chromatin margination similar to that described for wild-type embr

61 ody expression may have been aided by forced margination through collision with erythrocytes.

62 Here, we evaluate the effect of RBCs on margination through microfluidic studies in vitro and by

63 ation, such as plasma skimming and leukocyte margination, to separate leukocytes directly from whole

64 ity and use it as an express lane for a fast margination toward the wall.

65 of mature neutrophils from the bone marrow, margination, trafficking and transmigration through the

66 istone administration resulted in neutrophil margination, vacuolated endothelium, intra-alveolar hemo

67 Margination volume (MV) was calculated by subtracting tr

68 Leukocyte margination was differentially impaired in these mice du

69 t has long been known that platelets undergo margination when flowing in blood vessels, such that the

70 om blood flow to vesselwalls, also known as "margination",which promotes particle contact and adhesio

71 g their circadian oscillations and pulmonary margination, which contributes toward lung injury and se

72 n this study, an M-value of 0.2 indicated no margination, which was observed for all particle sizes i

73 Understanding the mechanisms that lead to margination will aid in tailoring the attributes of drug

74 No defect in neutrophil margination within either capillaries or arterioles and

75 00 red blood cell profiles) but no change in margination within noncapillary pulmonary microvessels.