ライフサイエンスコーパス: mark

1 on constitutes a rapidly adaptive epigenetic mark.

2 formatics of the nuclear organization of epi-marks.

3 ids self-elimination by evading two of these marks.

4 e ordinal scale: minimal, mild, moderate, or marked.

5 pc6 deletion on the SNO proteome became less marked.

6 s and flowers that they themselves had scent-marked, 2.

7 The epigenetic mark 5-hydroxymethylcytosine (5hmC) is a cytosine modifi

8 Rifted margins mark a transition from continents to oceans and contain

9 es-conserved peak was delayed in females and marked a reorganization of expression of synaptic and sc

10 by the Indian Ocean-Southern Pacific region, marking a transition from lower-than-average rates befor

11 age tracing revealed that the Krt15 promoter marks a long-lived basal cell population able to self-re

12 Our data show that Troy marks a renal stem/progenitor cell population in the dev

13 Activated MARK proteins (MARKs) accumulated in LB-like inclusions in this cell-ba

14 k, whereas flexible thin-film probes yield a marked accumulation of astrocytes and microglia and decr

15 me-wide analysis of DNA methylation, histone marking (acetylated lysine 9 in histone H3 and trimethyl

16 with the deposition of activating epigenetic marks across the loop domain, plausibly facilitating pha

17 n, it remains challenging to establish which marks actually have causative roles in gene regulation a

18 ic infiltration, excessive Th2 polarization, marked airway hyperresponsiveness, alveolar simplificati

19 This discovery marks an important advance in our comprehension of how m

20 TCF19 interacts with an active transcription mark and recruits a co-repressor complex to regulate glu

21 Over the study period, 7,427 hatchlings were marked and 380 individuals were recaptured for as many a

22 These data suggest that viral RCs can be marked and antagonized by a universal immune defense mec

23 ompression fractures and were electronically marked and classified by a radiologist.

24 foundly changed from previous tracings, with marked and diffuse voltage reduction (QS in V1-V3) and i

25 tion of Il5 (Tg) /Cd300f (-/-) mice revealed marked and distinct increases in eosinophil levels and t

26 LL2 complex reads the H4-Y88-phosphorylation marks and deposits the transcriptionally activating H3K4

27 of C3G failed to show repression of histone marks and did not show up-regulation of myosin heavy cha

28 aggressiveness marker, CD151 in humans thus marks and enables hyperproliferative T cells.

29 ein that binds phospho-Ser2 and phospho-Thr4 marks and facilitates transcription termination at prote

30 tudies have revealed that histone activation marks and repression marks are associated with activated

31 These epi-editors altered critical histone marks and subsequently Dlg4/PSD95 expression, which, imp

32 ed by characteristic signatures in chromatin marks and transcription factors (TF) that are consistent

33 of mutations, binding, motifs and epigenetic marks) and continuous data (e.g. gene expression, protei

34 some contacts among open chromatin, H3K27me3-marked, and H3K9me3-marked repressed chromatin regions.

35 ment of CTCF binding sites, promoter-related marks, and enhancer-related histone modifications.

36 This review will focus on the current CE-mark approved bioresorbable scaffolds, their basic chara

37 but neither compartment domains nor histone marks are affected.

38 that histone activation marks and repression marks are associated with activated and repressed gene e

39 sociated with Set1) to ensure that chromatin marks are not established until nutrient/energy continge

40 Pressed honey, can be marked as a differentiated product with a higher mineral

41 Tumor VOIs were marked as high-grade (>/=Gleason grade group 3) or not.

42 rneal epithelial super enhancers are already marked as potential regulatory domains in embryonic stem

43 Nuclear foci corresponding to epigenetic marks as well as heterochromatin and the nucleolus also

44 crotubule affinity-regulating kinase family (MARKs) as activated and insoluble in a neuronal culture

45 re the interplay between TADs and epigenetic marks, as tumor mutational burden is known to be coupled

46 imethylation of histone H3K36 is a chromatin mark associated with active gene expression, which has b

47 Here I present evidence of marked asymmetries between members of a functional pair

48 The impact was more marked at the flower-rich site (all colonies performed p

49 nctional, such as the presence of epigenetic marks at their transcription start sites, evolutionary c

50 ns after surgery, which was accompanied by a marked augmentation of pancreatic and intestinal BF resp

51 o-STAT3 and GAP43, which may account for the marked axonal growth across the lesion epicenter.

52 The fibrotic group had marked bleb scarring and vascularization and worse logMA

53 ns (CTDs) associate with the coiled-coil and marked-box domains (CMs) of E2Fs.

54 minimal or mild BPE, those with moderate or marked BPE were associated with higher abnormal interpre

55 ene expression, DNA methylation, and histone marks but these investigations have only been carried ou

56 ing and reversible freezing transitions were marked by 2-5 cm(-1) shifts in the radial breathing mode

57 iation between L1 insertions and gene bodies marked by a facultative heterochromatic mark, which coul

58 F-beta1, thereby allowing LC differentiation marked by a low cytokine expression profile.

59 the cytokine genes in the memory T cells are marked by activating histone modifications even in the r

60 the growth and fusion of palatal shelves, as marked by an increase in cell proliferation and osteogen

61 matin domains, i.e., genome regions that are marked by both H3K4me3 (activating) and H3K27me3 (repres

62 The identified domain boundaries are marked by characteristic signatures in chromatin marks a

63 Eukaryotic genes are marked by conserved post-translational modifications on

64 in myeloid-specific Egfr-deficient mice, as marked by decreased Arg1 and Il10 mRNA expression and de

65 ect significant changes in mRNP composition, marked by dissociation of eIF4G and PABP, and by recruit

66 ative 5 and 3'ss usage and exon skipping are marked by distinct patterns of ordered intron removal.

67 In mice, early VV formation is marked by elongation and reorientation ("organization")

68 debilitating and inefficient walking pattern marked by excessive knee flexion that worsens with age.

69 cellular resistance to viral replication is marked by expression of antiviral restriction factors, i

70 The recent evolution of cattle is marked by fluctuations in body size.

71 regranulosa cells; however, active enhancers marked by H3K27ac were enriched proximal to only Sertoli

72 sly occupied by Foxh1 and show that they are marked by H3K4me1, Ep300, and Fox/Sox/Smad motifs, sugge

73 Adolescence is a developmental period marked by heightened attunement to social evaluation.

74 subset of tumor-infiltrating CD8(+) T cells marked by high expression of the immunosuppressive ATP e

75 ty Co6Te8(CO)6 have closed electronic shells marked by high HOMO-LUMO gaps of 1.24 and 1.39 eV, respe

76 y proliferative and invasive adenocarcinomas marked by highly inflammatory, angiogenic, and immune-su

77 sequences and divergent enhancer activity as marked by histone 3 containing the acetylated lysine 27

78 hibitory proteins SOCS1, SOCS3 and CISH were marked by m(6)A, exhibited slower mRNA decay and showed

79 PHIP had extensive lymphocytosis marked by massive expansion of natural killer (NK) and T

80 lls, active or primed enhancers are commonly marked by monomethylation of histone H3 at lysine 4 (H3K

81 Anxious hypervigilance is marked by sensitized sensory-perceptual processes and at

82 acrophage activation was also detectable, as marked by significantly reduced Nos2 and Il1b mRNA level

83 olvement is frequent in PCNSL and clinically marked by slowly progressive visual deterioration, lymph

84 In contrast, in wines marked by these flavors, it never exceeded 20microg/L.

85 ain and kidney), resulted in rapid lethality marked by weight loss, changes in nutritional as well as

86 In contrast, DCs marked by Zbtb46-GFP or Snx22-GFP were less abundant, co

87 Reversal of the pY88-H4 epigenetic marks by the ACK1 inhibitor (R)-9bMS-sensitized naive an

88 inimal) and those with high BPE (moderate or marked) by using binomial tests of proportions.

89 l communities in bare fallowed soil showed a marked capacity to utilise phytate for growth compared w

90 the lesional keratinocytes associated with a marked CD4+ T cell infiltration, which peaked on days 10

91 d high cell-associated viral loads without a marked CD8 lymphocytosis or NK cell disturbance like tho

92 endoplasmic reticulum of BAs and displayed a marked change in fluorescence intensity in response to a

93 ern in the uptake of ozone by forests with a marked change in the magnitude, up to 1.9 TgO3 /year, an

94 proliferation, decreased cellular heme, and marked changes in cellular morphology so that the cells

95 A caused rapid Ca(2+) transient loss without marked changes in cytosolic and sarcoplasmic reticulum C

96 Similar but less marked changes were seen in PrP KO mice.

97 latyrhynchus) from 1994 to 2015, a period of marked climate warming.

98 In normal breast tissue, we observed a marked cohesiveness in both the ncRNA and mRNA layers an

99 m central Panama in conjunction with spatial mark-connection functions, we show evidence for NDisD fo

100 In marked contrast, Atm-deficient tumors displayed an enhan

101 In marked contrast, knee joints of Ddr2(slie/slie) mice wer

102 all subjects throughout the airway wall with marked cytoplasmic to nuclear shift in COPD (P < 0.01).

103 ss, from 150,000 to 45,000 years ago, then a marked decline indicating megafaunal population collapse

104 t in pancreatic insulin-positive area, but a marked decrease in CD3(+) cell infiltration.

105 as shown faster postoperative recovery and a marked decrease in pulmonary complications.

106 nding of Na(+) These experiments disclosed a marked decrease in the affinity of Na(+) to bind the cha

107 e oil content decreased significantly, and a marked decrease in the contents of carotenoids and chlor

108 slet Ag-specific regulatory T cells led to a marked decrease of Ccl5 and Ccl8, and a reduction of mon

109 in the northern North Atlantic have shown a marked decrease over the past several years.

110 Sulfur isotope anomalies and marked decreases in ice core bromine consistent with inc

111 ng human hepatoma cell line, which displayed marked defects in both PKA activation and isoproterenol-

112 Marked demographic and geographic differences exist.

113 Marked dependency on linker length was observed for BET-

114 doped YBa2Cu3O y Furthermore, the absence of marked deviation in [Formula: see text] at the onset of

115 house dust mites), specific IgE did not show marked differences between regions and specific IgG (>/=

116 y-tandem mass spectrometry analysis revealed marked differences between the proteins packaged within

117 is a breast cancer subtype characterized by marked differences between White and Black/African-Ameri

118 beta cells to subpopulations that exhibited marked differences in GSIS with parallel changes in endo

119 the monocyte/macrophage subsets and elicits marked differences in SIV infection and clinical outcome

120 The results show marked differences in specific peanut allergen profiles

121 We discuss how these marked differences in the biology of vaginal infection b

122 There were marked differences in the levels of amino groups between

123 There are marked differences in the spread and prevalence of HIV-1

124 e results suggest that Fringe modifications "mark" different regions in the Notch1 extracellular doma

125 rall, our findings reveal that patients have marked difficulties to exploit facial social cues elicit

126 that methylation plays an important role in marking DNA for transformation.

127 heimer's Disease (AD), are associated with a marked drop in the levels of important neurotransmitters

128 y and late gametocytes; heterochromatic PTMs mark early gametocytes.

129 y method that adjusted appropriately for the marked effect of BCG-attributable induration in the very

130 h the increase of droplet size, reflecting a marked effect of the water surface on the SO2 solvation.

131 llowed by ciprofloxacin administration had a marked effect on reducing UPEC titers within the bladder

132 and long distance cell dispersal can have a marked effect on tumor structure, high cellular motility

133 Breeder turnover had marked effects on the breeding opportunities of subordin

134 Strains lacking Paf1 show marked elongation defects, although low levels of Paf1 o

135 ciated with inflammatory disorders involving marked eosinophilia (e.g. asthma), were particularly ele

136 e concentrated to the basal lateral LV, with marked epicardial predominance.

137 epts an offered liver for transplant, with a marked fall in acceptance rates for livers with an index

138 as reported on both scent and composition of marking fluid (MF) from P. leo.

139 ination by disrupting at least three histone marks following fertilization, while PSR avoids self-eli

140 charge mortality was 50%, a prognostic bench mark for hospice referral.

141 the importance of this specific acetylation mark for PBRM1 binding.

142 requires C-terminal acetylation-a classical mark for transcriptionally active p53-and correlates wit

143 he Env response over Gag, substantially more marked for HLA-B*14:02.

144 ization chaperones and as molecular fiducial marks for single particle cryo-electron microscopy appro

145 mitochondria and melanosomes, and exhibited marked functional defects in phagocytosis of photorecept

146 baseline), hypoalbuminemia, reduced GFR, and marked glomerular damage.

147 Interestingly, betaTFG KO displayed marked glucose intolerance with reduced insulin secretio

148 at HIV-1 NL4-3(IN T124N/V165I/T174I) confers marked (>2000-fold) resistance to KF116.

149 They show that the histone mark H3K27ac and pluripotency transcription factors rema

150 SCs), accumulation of the repressive histone mark H3K27me3 is delayed after DNA replication, indicati

151 fication of sites bearing the active histone mark H3K4me2 in primary human colorectal cancers, as com

152 H3K27ac, and H3K36me3, but not the bivalent mark H3K4me2.

153 re, we have profiled 2 repressive epigenetic marks, H3K9me2 and H3K27me3, which are involved in stabl

154 also associate with the repressive chromatin marks H3K9me3 and methylated-CpGs, consistent with ORCA-

155 hat actively transcribed genes with Polycomb marks have greater cell-to-cell variation in expression.

156 nstall, recognize, and remove this and other marks have revealed roles for mRNA modification in nearl

157 isingly, the spread of repressive epigenetic marks (histone H3K9me2) to nearby DNA occurs at >50% of

158 phenotype, characterized by renal salt loss, marked hypokalemia, and metabolic alkalosis.

159 ated, 40 mL/kg of blood was removed yielding marked hypotension and a rise in plasma lactate.

160 q analysis for FOXF1 and histone methylation marks identified DNA regulatory regions within the Cd44,

161 ons in hospitalised cases of pneumonia and a marked impact on the incidence of severe childhood pneum

162 Despite this marked improvement in HSC phenotype, no significant chan

163 and data analysis techniques has resulted in marked improvements in detection sensitivity and size re

164 A as a gene-expression-associated epigenomic mark in eukaryotes.

165 wed large-scale assessment of one epigenetic mark in particular, DNA methylation, in human population

166 The reduction in DNT was particularly marked in China (P for trend, 0.001), but was not signif

167 The impact of Flicr is particularly marked in conditions of IL-2 deficiency, and, conversely

168 This is especially marked in soybean, the world's fourth largest food crop

169 ay compared with their term-born peers, most marked in the language domain.

170 sitive functional T cells and sustained gene marking in myeloid and B-cell lineages up to 20 months o

171 the abundance of several histone acetylation marks in Arabidopsis (Arabidopsis thaliana), which was s

172 esearch focuses on the utility of epigenetic marks in capturing this intersection of genes and enviro

173 ure is associated with changes in epigenetic marks in sperm, with a primary focus on the reprogrammin

174 of DNA methylation and repressive chromatin marks in the mammalian germline leads to risk of transcr

175 Wines from both treatments received similar marks in the sensory tests, suggesting that irrigation d

176 etinas, including near total RGC loss with a marked increase in amacrine cells in the ganglion cell l

177 analysis of ACC-deficient liver identifies a marked increase in antioxidants including NADPH and redu

178 The marked increase in APC function for allergen-specific TC

179 Activation of SGK1 in the heart causes a marked increase in both the peak and late sodium current

180 tander defibrillation were associated with a marked increase in bystander defibrillation in public lo

181 Denervation resulted in a marked increase in miR-206 and reduced expression of miR

182 The marked increase in NE in oGVHD tears that correlated str

183 Ecosystem restoration resulted in a marked increase in pollinator species, visits to flowers

184 linically and in a mouse model, results in a marked increase in the number of regulatory T cells in t

185 anulopoietic precursor cells, resulting in a marked increase in the ratio of immature Gr1(lo) cells i

186 genetic deletion of BRIT1 in mice leads to a marked increase in unrepaired Igh breaks and a significa

187 significantly reduced ATP sensitivity and a marked increase of channel activity in the intact cell i

188 ABP4 knockdown in endothelial cells led to a marked increase of endothelial fatty acid oxidation, an

189 of gallbladder bile acid composition showed marked increase of taurocholic acid and decrease of taur

190 owth medium supplemented with phytate led to marked increases in growth and total P content of Pi-def

191 d exposure of pulp cells to FGF2 resulted in marked increases in odontoblast differentiation.

192 HFE C282Y homozygosity had the most marked independent association with elevated iron stores

193 Furthermore, repressive chromatin marks influence ORCA's binding on chromatin.

194 ) murine livers, which was associated with a marked inhibition in antigen cross-presentation by Igfbp

195 f taurine up-regulated gene 1 (TUG1) induces marked inhibition of cell migration, invasion, and glyco

196 ed for longer-lasting effects, combined with marked inter-individual variability, necessitates a deep

197 n about how genetic variation and epigenetic marks interact to shape differences in behavior.

198 27me3 from adjoining areas of elevated basal marking into large well-demarcated genome domains.

199 Non-human animals sometimes show marked intraspecific variation in their cognitive abilit

200 Such a mark is suggested to play key roles in the regulation of

201 Now marking its 40th anniversary, percutaneous coronary inte

202 Further, inhibition of MARKs led to increased pathological alpha-synuclein burd

203 PI3K pathway protein inhibitors and observed marked leukemia reduction and in vivo signaling inhibiti

204 n of constitutive pepcan-12, as shown by its marked loss after adrenalectomy.

205 In addition, we observed marked loss of postsynaptic scaffolding proteins and red

206 ce results in accumulation of the epigenetic mark, lysine 5-acetylated H2B.

207 port the notion that differential epigenetic marking may facilitate long-term retention of duplicate

208 Thus Gli1 marks mesenchymal progenitors responsible for both norma

209 nced cytokine production was associated with marked metabolic changes in the Irgm1-deficient macropha

210 Malignant prostate cells showed marked metabolic derangements compared with their benign

211 changes include initial repressive polycomb marking of genes, later manifesting abnormal DNA methyla

212 istinct TOP2A CCR clusters that overlap with marks of transcription, open chromatin, and enhancers.

213 r drug overdose treatment without a question mark on the timing used in the animal models.

214 Two histone marks on histone H3, lysine 4 trimethylation (H3K4me3) a

215 ng evidence suggests presence of methylation marks on mitochondrial DNA (mtDNA); but their contributi

216 of superenhancers from genome-wide chromatin marks or DNA-interaction protein binding sites, there is

217 ated by the identified current proxies: tool marks, overfolded edges of Dickinsonia, felled fronds an

218 t the transcription factor Tbx18 selectively marks pericytes and vascular smooth muscle cells in mult

219 is likely because of the presence of histone marks permissive of gene activation.

220 Marked physicochemical differences were observed among a

221 ry environment in vivo, Th22 cells displayed marked plasticity toward IFN-gamma production.

222 in animals could benefit from an easy way to mark positive hits.

223 has unique subjective effects that include: marked positive mood, pleasant/unusual bodily sensations

224 a (PI3Kalpha/delta) inhibitor AZD8835 showed marked potency in ABC DLBCL models, whereas the protein

225 subpolar Atlantic Ocean, clear evidence of a marked pre-bloom silicate decline of 1.5-2 microM throug

226 te (PK) layers is presented, which reveals a marked preference for Mn to partition to the central lay

227 silences gene expression, while the H3K4me3 mark prevents the region from becoming permanently silen

228 transcriptionally activating H3K4-trimethyl marks promoting AR transcription.

229 lococcus aureus This procedure resulted in a marked propensity for a hematogenous implant-related inf

230 We also show the marked protective effect of PD-L1 expression on HCV-infe

231 Activated MARK proteins (MARKs) accumulated in LB-like inclusions

232 of Sema4c(-/-) CD19(+)CD138(+) cells induced marked pulmonary inflammation, eosinophilia, and increas

233 ructural equation modelling with 20 years of mark-recapture and nesting data across the breeding rang

234 11-y acoustic telemetry, stable isotope, and mark-recapture dataset to test if a population of lake t

235 ulation has been monitored with a systematic mark-recapture regime yielding a dataset of >15,000 capt

236 ient mouse and human T cells, which showed a marked reduction in activating phosphorylation of the TC

237 Glc-supplemented cells exhibited a marked reduction in levels of plastid transcripts encodi

238 CD11d deficiency led to a marked reduction in lipid deposition in aortas and isola

239 inhibition of the JNK pathway resulted in a marked reduction in reactivation of VZV.

240 gulator Bcl6 in CD4(+) T cells resulted in a marked reduction in TFH cell numbers and IgE antibody le

241 ignificant decrease in bone resorption and a marked reduction in the number of osteoclasts and inflam

242 Likewise, a marked reduction in uterine ILC2s was observed in mice d

243 ll interfering RNA (siRNA) or Mdivi-1 caused marked reduction in virus production.

244 The promoter (-918) with ARE showed a marked reduction in young vs aged hLECs, which was direc

245 reatment during the challenge phase led to a marked reduction of eosinophil and T cell numbers in bro

246 Despite the marked reduction of GC-A mRNA in GC-A KO podocytes to 1%

247 Our study indicates a marked reduction of ligand binding to D1 and D2 and 5-HT

248 After infusion of Cy, a marked reduction of proliferating NK cells was evident,

249 Despite marked regional differences in HIV susceptibility within

250 INTERPRETATION: Marked regional differences in mortality in patients wit

251 netic mark that distinguishes cell types and marks regulatory elements.

252 ading factor Nipbl in mouse liver leads to a marked reorganization of chromosomal folding.

253 hing mechanism that senses proton binding by marked reorganization of subunit interface, altering the

254 open chromatin, H3K27me3-marked, and H3K9me3-marked repressed chromatin regions.

255 scarcely investigated low-abundance histone marks, revealing that concentrations of acyl-CoAs affect

256 strates a mechanism that plays a role in the marked sexual dimorphism observed in a model of the tran

257 The H3K27me3 mark silences gene expression, while the H3K4me3 mark pr

258 adulthood and, at 6 months of age, exhibited marked splenomegaly and leukophilia.

259 chromosome (Xp) and enrichment in epigenetic marks such as H3K27me3 is achieved by the early blastocy

260 ugh metabolomic and transcriptomic profiling marked suppression of glucocorticoid biosynthesis in the

261 One compound, 3ch, showed particularly marked sustained effects, with a reversal t1/2 > 6 hours

262 ubcortical regions, a function that requires marked synaptic plasticity.

263 All four had marked systemic inflammation, fever and fluctuating radi

264 on T cells, we explored whether CD151 would mark T cells in a hyperactivated state.

265 DNA methylation is a stable epigenetic mark that distinguishes cell types and marks regulatory

266 comb repressive complex 2 and the epigenetic mark that it deposits, H3K27me3, are evolutionarily cons

267 ICTS to resolve cellular states based on epi-marks that cannot be detected via mass spectrometry base

268 ined as repressive and activating epigenetic marks that simultaneously decorate the same genomic regi

269 To mark the 100th birthday of R.

270 ator domains require further refinement, and mark the beginning of an ongoing consultation process-fr

271 o coordinate trafficking into the furrow and mark the center of the cell in lieu of a midbody/phragmo

272 dius of curvature, and high electric current mark the electron diffusion region.

273 The results thus mark the first acceleration of a distinct positron bunch

274 ERPRETATION: These neonatal herpes estimates mark the first attempt to quantify the global burden of

275 Here we use genetic lineage tracing to mark the Nppa(+) or Hey2(+) cardiomyocytes as trabecular

276 tial use of their quantity in human serum to mark the pathological elicitation of these cells in vivo

277 Tacit knowing: 2016 marked the 125th anniversary of the birth of the physica

278 Pedersen marked the beginning of research on cyclic polyether mac

279 reversible Buchner ring expansion reactions, marking the first examples where both cyclopropanation a

280 ure and then passes through the minimum that marks the 3D-2D crossover in the system.

281 This year marks the 50th anniversary of Charles Pedersen's discove

282 sna-DP specifically marks the early primordia for both the wing and haltere,

283 Senescence is the process that marks the end of a leaf's lifespan.

284 Growth along the phagophore rim marks the progress of both organelle expansion and ultim

285 This year marks the tenth anniversary of the identification of the

286 ion of the Journal of Clinical Investigation marks the transition to a new editorial team from Johns

287 dogenous proteins as inflammatory stimuli by marking them for recognition by TLRs.

288 We demonstrated marked though distinct anti-silencing activity in the pl

289 approaches can infer function for chromatin marks through correlation, it remains challenging to est

290 hat dKDM4A demethylates this heterochromatic mark to facilitate repair.

291 degradation by K-Rta shifts bivalent histone marks to a more active configuration, leading to KSHV re

292 pathogenic, double-stranded DNA virus with a marked tropism for cells of the monocyte-macrophage line

293 Marked variations in mutation loads were seen with diffe

294 there are large individual differences, with marked vulnerability or resilience among individuals.

295 DNA methylation, a major epigenetic mark, was investigated using targeted bisulfite sequenci

296 ors, enhancer regions, and different histone marks were enriched in the T2D-associated DMRs.

297 ther; the degree of clinical acceleration is marked when the 2 coexist.

298 dies marked by a facultative heterochromatic mark, which could explain the observed bias for L1 inser

299 ino acid transporters, derepression of genes marked with histone H3 lysine 27 trimethylation (H3K27me

300 pertrophied rat hearts, and correlated these marks with their associated transcriptomes.