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1 xport of NFkappaB from the nucleus decreased markedly.
2 duction and thermal Fe(III) reduction differ markedly.
3 stimulated, and muscle fiber size decreased markedly.
4 and found that TasP's effectiveness differs markedly.
6 lation with keratinocyte growth factor (KGF) markedly accelerated mortality after infectious challeng
7 display mild macrothrombocytopenia due to a markedly accelerated platelet clearance in the spleen.
10 ren <5 y old, lower percentile ranges varied markedly across age and sex such that the single cutoff
12 or and impaired aversive learning as well as markedly affected motor function including disordered co
14 n identified as an environmental factor that markedly affects energy storage and body-fat accumulatio
15 and sensible management of dyslipidemia can markedly alter cardiovascular morbidity and mortality.
16 AR action, such as NOV and ST6GalNAc1, were markedly altered, which indicated reduced androgen actio
17 eriod in which malaria transmission declined markedly, AMA1 and MSP2 antibodies decreased substantial
18 el indicated that population trends differed markedly among fjords, as did estimates of population pa
20 trol, hypoxia and rapamycin treatment showed markedly amplified PLA signals for IGFBP-1 and CSNK-2bet
22 hort hairpin RNA construct was sufficient to markedly and persistently elevate ingestive behavior and
23 se cotransporter 2 inhibitor, empagliflozin, markedly and rapidly reduced CV death and heart failure
26 allergen stimulation in vivo accompanied by markedly attenuated inflammatory cytokine release in res
27 s did not protect the mice from obesity, but markedly attenuated the obesity-induced lipid accumulati
31 lectins, we managed to take advantage of the markedly atypical glycomic profile of the cancerous mamm
33 eted NPs relative to non-targeted NPs showed markedly better inhibitory effects on apoptosis and oxid
34 IRE-3, patients with left-sided tumors had a markedly better prognosis than those with right-sided tu
36 activity, because N(G)-monomethyl-l-arginine markedly blunted the flow response to obestatin in both
38 l LTC4 to allergen sensitized wild-type mice markedly boosted ILC2 expansion and IL-5/IL-13 generatio
39 with influenza virus H1N1 or H3N2 and found markedly broad responses and cogent evidence for 'origin
41 rgeted molecular therapy, ephrinA1, known to markedly collapse the cytoplasm of cells expressing the
43 oss of dermal white adipose tissue (WAT) and markedly decreased abdominal WAT that was characterized
44 te of hepatocellular carcinoma occurrence is markedly decreased after a sustained virological respons
45 from intermediate phases of papaya ripening markedly decreased cell viability, induced necroptosis,
47 though inhibition of PI3K-AKT-mTOR signaling markedly decreased glycolysis and restrained tumor growt
48 re significantly elevated, while miR-26b was markedly decreased in AAAD+ serum samples compared with
49 vity toward the peptide substrate S-2288 was markedly decreased in all HABP2 variants, with G221E bei
51 icron, a glutamate-fermenting commensal, was markedly decreased in obese individuals and was inversel
54 s and recruitment of inflammatory cells, and markedly decreased metastasis to the lung and liver in m
55 the glial and neuronal glycine transporters markedly decreased PV+ IN excitability, as assessed by a
58 e duration from milliseconds to microseconds markedly decreases the minimal pulse energy required for
59 predicted by the reporter assay, while also markedly decreasing transcription, demonstrating an unex
60 on this mapping, neighboring neurons showed markedly different affiliation with distant visually res
63 pulations subject to less drug pressure show markedly different dynamics, including cases of acquisit
65 bsence of clinical symptoms was notable, and markedly different from that seen in previous typhoid ch
66 behaviour of (Al,Fe)-bearing bridgmanite is markedly different from the behaviour of the MgSiO3 endm
67 ted forms with very different pore openings, markedly different gas-adsorption capacities and differe
68 nchymal liver cells grown in ALTCs exhibited markedly different gene expression when compared to stan
71 g development, but the contribution of their markedly different life-history phases to macroevolution
73 identical SSU rRNA sequences the strains had markedly different properties, and could be distinguishe
74 ogeneity whereby different filopodia display markedly different responses to changes in the accumulat
76 thacin-acyl-glucuronide are found to exhibit markedly differential binding to these GusR orthologs.
77 ronounced reduction in lesion severity, with markedly diminished numbers of T cells and nonlymphoid i
79 3G mutant, even under native conditions, was markedly disordered, suggesting that the beta-annulus ha
81 iRNA profiling demonstrated that miR-30a was markedly downregulated in diabetic cataract tissues.
82 ruption of the mutant allele in PF-382 cells markedly downregulated LMO2 expression, establishing cle
83 the proportion of natural killer T cells is markedly elevated during liver regeneration and their ac
84 The Cancer Genome Atlas (TCGA) and reveal a markedly elevated expression of the GLUT1 glucose transp
86 Furthermore, the IL-10 expressing NK cells markedly enhanced angiogenic responses and placental dev
87 We report that removal of GreA results in markedly enhanced break repair via the classic RecBCD-Re
89 , but not its transmembrane domain, induce a markedly enhanced or reduced gammadelta T cell reactivit
94 r parasite burdens (P < 0.01), and displayed markedly enhanced survival versus the wild type (WT) whe
95 f ADSCs along with BA-DEG-BA into mouse ears markedly enhanced the adipogenic differentiation of ADSC
96 me course of muscle tissue regeneration, and markedly enhanced the engraftment of muscle stem cells i
98 as(G12V) and Braf(D631A) in mouse lung cells markedly enhances tumour initiation, a phenomenon mediat
99 reticulum (ER), ranging from vesicular ER to markedly expanded cisternae with accumulation of moderat
101 d and a single polymorphism at codon 132 can markedly extend CWD latency when the minor leucine allel
104 , we show that the embedded rigid inclusions markedly facilitate stretch-induced membrane disruptions
105 ologically associating domains, as switching markedly favors local (short-range) contacts over distan
110 matin in embryonic stem cells (ESCs) differs markedly from that in somatic cells, with ESCs exhibitin
111 ature of these LCM-captured neurons differed markedly from that the gene expression patterns found pr
112 yptophan radicals shows kinetics that differ markedly from those of closely related members of the cr
114 erminant sialyl Lewis X (sLe(X)) and display markedly greater adhesive interactions with E-selectin t
116 w sIgE/sIgG4 ratios in VIT patients, showing markedly higher allergen-blocking capacity (P < .001).
117 arbonaceous PM emission and SOA formation is markedly higher from gasoline than diesel particle filte
119 th during the first year after discharge was markedly higher than the risk of death beyond the first
120 ndeed, MFIs of the de novo allo-HLA Abs were markedly higher with FcMonoIgG than with IgHPolyFab.
121 urther reduced blood glucose levels into the markedly hypoglycemic range in overnight-fasted, strepto
124 in DIV7 cultures of E18 cortical neurons was markedly impaired at the embryonic stage, even though hy
125 of M. tuberculosis-specific CD4 T cells was markedly impaired in HIV-infected individuals, compared
127 hat interfering with AMPAR surface diffusion markedly impairs synaptic potentiation of Schaffer colla
128 of KRas(G12D) in mouse lung epithelial cells markedly impairs the progression of KRas(G12D) -driven l
129 Our data suggest that mutated desmin already markedly impedes myocyte structure and function at pre-s
130 with antigen (Ag) peptides and adjuvants can markedly improve Ag/adjuvant co-delivery to lymphoid org
131 long-term forecasting could be exploited to markedly improve management of future energy systems.
132 e-scale metagenomic shotgun sequences, which markedly improve metagenomic data analysis and interpret
135 set of carboxylate derivatives demonstrated markedly improved in vitro metabolic stability (t1/2 > 2
137 enzyme activity results indicated that CAPB markedly improved the aerobic microorganism activities.
138 K inhibition (BRAFi and MEKi) therapies have markedly improved the clinical outcomes of patients with
140 tion correction of hybrid (18)F-fluoride PET markedly improves SNR, resulting in improved image quali
141 n a large reduction in bacterial numbers and markedly improves survival compared to untreated mice.
142 T cells with an Akt-insensitive Ezh2 mutant markedly improves their memory potential and capability
143 and 2011-2012, added-sugars intake declined markedly in adult men (from 72 to 59 g/d; -18%) but not
144 ion after carotid artery wire injury reduces markedly in CD40(-/-) apolipoprotein E-deficient (apoE(-
148 ct of dichloromethane on ozone has increased markedly in recent years and if these increases continue
149 iological questions, as each variant differs markedly in resolution, reproducibility, throughput and
150 ctral attributes of LCO-bound plaques varied markedly in the brain, but the mean spectral properties
153 Though lentiviral Nef proteins differed markedly in their absolute MHC-A and MHC-B downregulatio
155 effects of mixing easy trials, which differ markedly in their timescales, in their effects on subjec
156 inistered in combination with SP (1 microM), markedly increase (by 1,000-fold) TNF gene expression in
157 zation and immune cell activation is able to markedly increase therapy response in silico These resul
158 henylpropanoids occurred in scoparone, which markedly increased 3days after exposing fruits to a very
160 ndothelial cells (n=12-15) or SMCs (n=13-24) markedly increased atherosclerotic lesion formation in h
161 ome assembly factor Bop1 in a 3T3 cell model markedly increased cell recovery after exposure to campt
164 ntly, in asthmatic patients pDC numbers were markedly increased during exacerbations and correlated w
165 found that LCE3B/C-del was associated with a markedly increased expression of LCE3A, a gene directly
170 hat numbers of basophils and mast cells were markedly increased in the jejunal mucosa during primary
171 d glutamate transmission to AVPV neurons and markedly increased it to arcuate kisspeptin neurons, whi
172 to the SIVmac239 envelope glycoprotein (Env) markedly increased its neutralization sensitivity to rhe
173 for Pten and Erk5 (prostate DKO) exhibited a markedly increased median survival with reduced tumor si
175 mors, pretargeting with both fusion proteins markedly increased nanoparticle targeting to both tumor
176 the restriction factor SAMHD1 resulted in a markedly increased number of EdU puncta, allowing effici
177 ), but not macroautophagy (3-methyladenine), markedly increased PNPLA3 levels in WT mice, coincident
178 l blood mononuclear cells with HMBA led to a markedly increased production of IL-12 and IFN-gamma, bu
179 ntly 2 studies have been published reporting markedly increased rates of tumor recurrence and occurre
181 miquantitative analysis of SPTs demonstrated markedly increased reactivity to grass compared to birch
184 ns in whole aorta and aortic root area, with markedly increased SRA expression in aortic root lesions
185 e in ataxin-2 reduced aggregation of TDP-43, markedly increased survival and improved motor function.
186 trated that covalent labeling followed by MS markedly increased the predictive power of the integrati
187 Finally, knockdown of liver CES1 in mice markedly increased the susceptibility to high cholestero
189 nstrate that disrupting the uORFs results in markedly increased translation efficiencies in luciferas
192 , we confirmed in whole animal that GJA1-20k markedly increases endogenous myocardial Cx43 gap juncti
193 genic low carbohydrate, high fat (LCHF) diet markedly increases rates of whole-body fat oxidation dur
197 ain tissues clearly displayed that n-3 PUFAs markedly inhibit the activation of astrocytes and protec
199 nd activation, promotes MYC degradation, and markedly inhibits cancer cell growth and metastasis.
201 onversely, rates of low-grade DCIS and, less markedly, intermediate-grade DCIS decreased in subsequen
202 s in informing the adaptive immune response, markedly less attention has been paid to the role of pos
203 during a 20 min trial in the dark phase, but markedly less during the light phase (421 +/- 83 mul, P
205 stems where fish diversity and abundance are markedly lower and algal biomass substantially higher, i
206 ng the renal transplant group with STEMI was markedly lower compared with the stage 5D CKD group (AOR
207 n TB14 rats, whereas de novo lipogenesis was markedly lower in the incorporation of glucose into fatt
210 95) undergoes K63 polyubiquitination, which markedly modifies PSD-95's scaffolding potentials, enabl
213 eplication-competent Ad (RC-Ad) vaccines are markedly more potent but risk causing adenovirus disease
215 n on endogenous glucose production (EGP) are markedly more sensitive than for stimulating glucose dis
216 ertical distribution within the canopy, with markedly more sensitivity to upper canopy leaf quality.
217 e find that m(6)Am-initiated transcripts are markedly more stable than mRNAs that begin with other nu
218 sults suggest that mutation rates can evolve markedly over short evolutionary timescales and suggest
219 ry needs in untreated dentition sextants but markedly overestimated surgical access needs remaining a
220 whereas the prevalence of AMI has increased markedly, particularly among patients with non-ST elevat
221 with an immune modulating effect, leading to markedly prolonged survival of donor swine skin xenograf
222 chnique in vitro Our results showed that PNE markedly prolonged the apneic response and exacerbated t
223 btle, but by curtailing Treg activity, Flicr markedly promotes autoimmune diabetes and, conversely, r
225 N-piperidinyl)methylbenzamide derivative 13d markedly protects beta-cells against ER stress-induced d
226 tegrated quantum optics has the potential to markedly reduce the footprint and resource requirements
228 ith Chlamydia, CCR7-deficient mice displayed markedly reduced Ag-specific CD4 T cell responses within
229 ht phase centred on ca. 1.8-1.1 ka BP led to markedly reduced C accumulation and potentially a hiatus
233 strated that plasma clearance of cortisol is markedly reduced during critical illness, explained by s
234 dularity-a measure of network segregation-is markedly reduced during episodic memory retrieval relati
235 in NCKX4(-/-);CNGB1(DeltaCaM) mice displayed markedly reduced EOG amplitude accompanied by alteration
237 in platelet-leukocyte complex formation and markedly reduced generation of factor Xa and thrombin on
238 In purified stimulated human B cells, 9cRA markedly reduced IgE production and enhanced IgA product
241 genesis and luminal cell differentiation, is markedly reduced in mammary epithelial cells of transgen
243 n by occlusion of the middle cerebral artery markedly reduced infarct size, and this correlated with
244 Substitution of the Lys residues to Glu markedly reduced integrin binding of E128K IL-1beta, sug
246 out-of-hospital cardiac arrest do not have a markedly reduced left ventricular ejection fraction.
247 ng, mutants of some of these genes exhibited markedly reduced levels of eDNA and a concomitant reduct
248 tion required for antibody functionality and markedly reduced levels of endotoxin contamination.
250 ciated with significant organ protection and markedly reduced mortality compared with nontreated cont
251 rosis factor-alpha (TNF-alpha) secretion and markedly reduced neuronal viability compared with neuron
252 ubfractions; at either A3GALT2 or NRG4, with markedly reduced plasma insulin C-peptide concentrations
254 and clofarabine treatments (38% +/- 3) but a markedly reduced relapse rate (44% +/- 3 vs 35% +/- 3) i
256 ation of Srebf-2 in hepatocytes of mice also markedly reduced SREBP-1c and the expression of all gene
258 itters GABA or glutamate within this circuit markedly reduced the capacity for prolactin action both
259 phosphorylation site for basophilic kinases, markedly reduced the endocytosis, whereas phosphomimetic
262 BCNPs have superior therapeutic efficacy and markedly reduced toxicity as compared to the nontargeted
264 lung at 5 days postinfection (p.i.) and had markedly reduced weight loss, pulmonary inflammatory cel
265 the right anterior insula and amygdala were markedly reduced when participants received painful ther
266 ; the percentage of intron retention (IR) is markedly reduced whereas that of alternative acceptor si
267 ined for centuries by traditional practices, markedly reduced while the number of woody species, asso
271 pressing CRPC cell line and xenograft models markedly reduces tumor growth through inhibition of mTOR
273 ost ATP injection 1 week after the first one markedly reinforced the stimulatory effect of a single i
274 r data suggest that chromatin may exist in a markedly relaxed state after fertilization, followed by
275 ating AAV-NT mice with a sirtuin-1 inhibitor markedly reversed many of the observed anti-inflammatory
277 S1 inhibition or TBM mutated TRF1 expression markedly sensitizes cells to telomere oxidative damage a
278 parable numbers of structural variations and markedly similar DNA methylation and transcriptome profi
280 evealed four beta propellers, in an assembly markedly similar to those of other protein complexes tha
281 no effect on the first action potential but markedly slowed repolarization of late spikes during rep
282 reating mice with intracranial GBM xenograft markedly slows tumor growth and provides a significant s
283 latively low temperatures is attributed to a markedly small difference in Gibbs free energy compared
284 mino acids, and LOG2 self-ubiquitination was markedly stimulated by the GDU1 cytosolic domain, sugges
287 king basal CDK1-mediated S81 phosphorylation markedly suppresses AR activity and initiation of this p
289 eceptor (CSF-1R), blocks glioma progression, markedly suppresses tumor cell proliferation and reduces
291 y and depression affect 30% of youth but are markedly undertreated compared with other mental disorde
293 otein 1 (MCPIP1; also known as regnase-1) is markedly upregulated in human psoriatic skin lesions.
294 w for the first time that inhibitory RGMa is markedly upregulated in multiple cell types after clinic
295 ion of claudins, in particular claudin-1, is markedly upregulated in the podocyte, accompanied by a t
296 ecursor cells, but Tet1 mRNA levels decrease markedly with completion of cell differentiation, corres
298 tribution on HIV-specific CD4 T cells varies markedly with respect to the functional subset of CD4 T
300 ly, or as a single bolus at postnatal day 1, markedly worsened AAA outcomes in XY in comparison with
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