ライフサイエンスコーパス: marsupial

1 from female tammar wallabies (an Australian marsupial).

2 n eutherian albinos are also present in this marsupial.

3 roughly the same size as the smallest living marsupial.

4 cific methylation at other imprinted loci in marsupials.

5 d gene segments and is likely present in all marsupials.

6 d controls LTR/non-LTR retrotransposition in marsupials.

7 pansions of the repertoire in placentals and marsupials.

8 therian mammal, but have not been studied in marsupials.

9 logenetic analysis of basal metatherians and marsupials.

10 about the development of immunocompetence in marsupials.

11 in which they have been searched, including marsupials.

12 , were linked to the origin and evolution of marsupials.

13 orders of mammals, including monotremes and marsupials.

14 r dentition of this strange group of extinct marsupials.

15 mmaretroviruses from rodents to primates and marsupials.

16 1s are present both in placental mammals and marsupials.

17 rse assortment of mammals (one monotreme, 11 marsupials, 37 placentals), including 11 new sequences,

18 that recapitulates the genome of an ancient marsupial AAV that circulated among Australian metatheri

19 le sequences completely contained within the marsupial-alignable sequences.

20 In these insectivorous marsupials, all males die after mating, when failure of

21 n mistakenly termed 'placental mammals', but marsupials also have a placenta to mediate early embryon

22 fant and fetal development in eutherians and marsupials, although marsupials have a far more complex

23 , its host range now includes other mammals, marsupials, amphibians, and reptiles.

24 of the mistletoe, two key seed-dispersers (a marsupial and a bird), and a pollinator (hummingbird).

25 Marsupial and eutherian mammals have been evolving indep

26 3- to 6-fold lower than in humans and other marsupial and eutherian mammals, as determined by lympho

27 Marsupial and placental brain size partial correlations

28 ity at the pivotal clavicle-sternal joint in marsupial and placental gliders.

29 ary to reports that IGF2R binds IGF2 only in marsupial and placental mammals, we found positively sel

30 inding protein in the common stem lineage of marsupial and placental mammals.

31 lutions of gliders within arboreal groups of marsupial and placental mammals.

32 ted precursor, DSP-PP, which is conserved in marsupial and placental mammals.

33 in expression status for X-linked genes in a marsupial and sheds light on the regulation and evolutio

34 terminus is deleted in the rod opsin of both marsupials and all eutherian mammals.

35 onventional TCR that was first discovered in marsupials and appears to be absent from placental mamma

36 Many developmental functions in marsupials and eutherian mammals are accomplished by dif

37 These findings suggest that diprotodont marsupials and eutherian mammals share a similar cortica

38 the difference between allometric slopes for marsupials and eutherians is no longer significant and t

39 GF2R imprinting and receptor IGF2 binding in marsupials and eutherians, our results also demonstrate

40 lar similarity between term pregnancy in the marsupials and implantation in eutherian mammals using t

41 In marsupials and in extraembryonic tissues of placental ma

42 In marsupials and in the early mouse embryo, X chromosome i

43 In marsupials and mice, the paternally derived X chromosome

44 y of Mesozoic mammals, related tritylodonts, marsupials and monotremes but not in living eutherian (p

45 erences in T cell subset development between marsupials and placental mammals.

46 tain lineages that predate the separation of marsupials and placental mammals.

47 Tribosphenic molars of basal marsupials and placentals are a major adaptation, with t

48 tative comparison of brain size evolution in marsupials and placentals, whose reproduction and metabo

49 p belonging to the lineage leading to modern marsupials and placentals.

50 itochondria and chloroplasts and in tRNAs of marsupials and rats, (e) a diverse nucleotide substituti

51 In marsupials and the extra-embryonic region of the mouse,

52 metatherians (the stem-based clade formed by marsupials and their extinct relatives), or as an outgro

53 They occur in both placental mammals and marsupials and thus are thought to have been present in

54 mammals, but its importance to imprinting in marsupials and, thus, the evolutionary origins of the im

55 ancestral state more closely than most other marsupials and, to some extent, even monotremes.

56 p, with two notable exceptions-metatherians (marsupials) and euarchontans (primates and their close r

57 asiatherian), tenrec (afrotherian), opossum (marsupial), and two non-mammalian tetrapods (anole lizar

58 Xist is not found in metatherians (marsupials), and how X-chromosome inactivation is initia

59 imilar pattern to the wallaby, a diprotodont marsupial, and to eutherian species.

60 ditions, which occurs in many small mammals, marsupials, and birds.

61 or has been identified in several tissues in marsupials, and its expression has been suggested in tis

62 nzyme was found in multiple primate genomes, marsupials, and more distantly related vertebrates, but,

63 lution of the common ancestor of monotremes, marsupials, and placentals.

64 40 Ma) alongside progenitors of other desert marsupials, and thus occupied seasonally dry heterogenou

65 mmalian lineages: occurring at least once in marsupials, apes, and cattle, and at least twice in rode

66 Marsupials appear unique by having an additional TCR: mu

67 Marsupials are a distinct lineage of mammals notable for

68 Marsupials are believed to be the only non-primate mamma

69 Marsupials are largely confined to Australasia and to Ce

70 Our results suggest that marsupials are prime sequencing candidates.

71 Our results show that the misconception that marsupials are systematically smaller-brained than place

72 anations for reduced female recombination in marsupials as a consequence of the metatherian character

73 indings are consistent with reports in other marsupials as well as with studies in a number of euther

74 ever, morphological changes in the uterus of marsupials at term mimic those that occur during implant

75 More distant comparisons (marsupial, avian, amphibian, and fish) failed to identif

76 nodelphis domestica, is consistent with this marsupial being an exception to the pattern.

77 and agnathans, and the first MAGP2 genes in marsupials, birds and teleosts.

78 human sequence and 20 orthologous regions in marsupials, birds, fish, and mammals.

79 Monodelphis domestica, a marsupial born at an extremely immature stage, and rats

80 we report several novel findings concerning marsupial brain development and organization.

81 gh number of nonneurons suggests that in the marsupial brain nonneurons may play a significant role i

82 nd conserved in orthologous locations in the marsupial, but its genome-wide dispersal postdates the d

83 moderately rapid rates, similar to those of marsupials, but large species attained rates comparable

84 It has been observed in mammals and marsupials, but not in birds.

85 from crossed fibres prechiasmatically in the marsupials, but not in the eutherians.

86 In marsupials, by contrast, uncrossed axons never approach

87 France that provide conclusive evidence for marsupial care of brood-offspring.

88 The Tasmanian devil, a marsupial carnivore, is endangered because of the emerge

89 an devil (Sarcophilus harrisii), the largest marsupial carnivore, is endangered due to a transmissibl

90 umber of other mammals including monotremes, marsupials, carnivores, and primates, the anterior parie

91 , as well as more specific clades, including marsupials, carnivores, rodents and nonhuman primates.

92 ing normal, unperturbed mitosis in human and marsupial cells.

93 CENP-B box) shown herein to selectively bind marsupial CENP-B protein.

94 all living placentals, from the metatherian-marsupial clade.

95 d as a broader pattern evident amongst other marsupial clades.

96 tals than they do with Metatheria (including marsupials), constitute Eutheria.

97 ans (Malacostraca: Peracarida), a lineage of marsupial crustaceans, show an interesting variety of br

98 immunoincompetent window period during early marsupial development.

99 The optic chiasm of marsupials differs from that of the eutherian brains tha

100 and the molecular estimate for the placental-marsupial divergence.

101 Molecular screening of a marsupial DNA panel indicated that mAAV-EVE1 occurs spec

102 In marsupials, dosage compensation involves silencing of th

103 their focus on gestation, as opposed to the marsupial emphasis on lactation.

104 underwent a major loss of diversity early in marsupial evolution.

105 Therefore there is a much greater demand on marsupial females during post-natal lactation than durin

106 Thus, neither marsupial follows a pattern of coevolution of V(H) and V

107 Except for a large GC decrease in marsupial genes, we found no general decreasing trend in

108 The availability of the first marsupial genome sequence allows investigation of these

109 the sequence composition of centromeres in a marsupial genome that harbors large amounts of centric a

110 nes colocalized with human PAR1 genes in the marsupial genome, confirming that the human PAR1 and PAR

111 he essential imprinting effector, DNMT3L, in marsupial genomes and the demonstration of a differentia

112 that also has endogenous representatives in marsupial genomes.

113 oss a wide range of mammalian (placental and marsupial) genomes suggests an evolutionary conserved re

114 t large-scale comparative analysis involving marsupial genomic sequence and demonstrates that such co

115 kangaroo endogenous retrovirus (KERV) in the marsupial genus Macropus.

116 the possibility of a similar process in the marsupial germ line.

117 As in eutherians, marsupial H19 is maternally expressed and paternal methy

118 A small marsupial has thrown new light on the question of why fe

119 hylogenetic position within australidelphian marsupials has long been debated, and here we provide st

120 pment in eutherians and marsupials, although marsupials have a far more complex milk repertoire that

121 Here, we show that marsupials have an additional TCR (TCRmu) that has V, D,

122 This model is appealing because marsupials have no Xist gene and the marsupial inactive

123 However, no marsupials have yet been examined.

124 Platypus TCRmu differs from its marsupial homolog by requiring two rounds of somatic DNA

125 Marsupials, however, provide interesting immunology prob

126 In marsupials, however, the placental attachment is short-l

127 t with retroelement amplification in several marsupial hybrid genomes.

128 retrotransposons, as shown to be the case in marsupial hybrids.

129 To further understand the marsupial immune system, the Ig repertoire of the short-

130 However, unlike marsupials, in the tree shrew, optic fascicles in the ch

131 because marsupials have no Xist gene and the marsupial inactive X chromosome is epigenetically dissim

132 conserved for >80 My of evolution among all marsupials (including the opossum and the Australian tam

133 sly been detected in a variety of Australian marsupials, including koalas and western barred bandicoo

134 The subclass Theria of Mammalia includes marsupials (infraclass Metatheria) and placentals (infra

135 Marsupials instead achieve brain sizes comparable to pla

136 rted by recent studies, proposes that XCI in marsupials is achieved through inheritance of an already

137 ests that X-chromosome inactivation (XCI) in marsupials is characterized by exclusive, but leaky inac

138 t the retina of Monodelphis, a polyprotodont marsupial, is generated in a similar pattern to the wall

139 In contrast to the notion that the marsupial isocortex contains a low density of neurons, w

140 For the large GC decrease in marsupials, it could be mainly due to the great reductio

141 ain size partial correlations differ in that marsupials lack a partial correlation of BMR with brain

142 terial ornithine and lysine cyclodeaminases, marsupial lens proteins and, in man, a thyroid hormone-b

143 um, whereas the approximately 100- to 130-kg marsupial lion, Thylacoleo carnifex, the world's most sp

144 Marsupial mammal relatives (stem metatherians) from the

145 ian mammals (0.772) is greater than that for marsupial mammals (0.590); (c) among families of birds,

146 ion predated the separation of placental and marsupial mammals and that differential gene loss and du

147 Marsupial mammals are born in an embryonic state, as com

148 y systematically across the isocortex of the marsupial mammals examined.

149 Placental and marsupial mammals exist in three states of consciousness

150 sociated abdominal muscles of monotremes and marsupial mammals have remained unresolved.

151 hiasmatic architecture between eutherian and marsupial mammals.

152 n two cases, convergent across placental and marsupial mammals.

153 unique phylogenetic position of metatherian (marsupial) mammals and the fundamental biologic characte

154 as been identified in therian (eutherian and marsupial) mammals but not in prototherian (monotreme) m

155 Like eutherians, metatherian (marsupial) mammals have evolved high CpG substitution ra

156 several rodent species, and six metatherian (marsupial) mammals.

157 han previous fires, (ii) herbivory by native marsupials may limit seedling survival in both burned an

158 t functions in the visual cycle and that the marsupial mole is blind with degenerate eyes, this findi

159 ic placement of the monito del monte and the marsupial mole remains unclear.

160 However, the marsupial mole sequence contains three frameshift indels

161 Using the marsupial Monodelphis domestica, here we identify Rsx (R

162 in the male germline and female soma of the marsupial Monodelphis domestica.

163 imary visual area, V1, in the South American marsupial Monodelphis domestica.

164 be conserved comparing Homo sapiens with the marsupial, Monodelphis domestica.

165 lineages represented by Homo sapiens and the marsupial, Monodelphis domestica.

166 vores, as well as 37 other taxa representing marsupials, monotremes, and all but two orders of placen

167 ark (a holocephalan), but we find it also in marsupials, monotremes, lizards, turtles, birds, and fis

168 acroura, formerly known as the narrow-footed marsupial mouse.

169 n some lineages, may be a derived feature of marsupial neocortex, or may be a feature particular to m

170 The alpha1,3GT gene is active in marsupials, nonprimate placental mammals, lemurs (prosim

171 clude that Necrolestes is related neither to marsupials nor placentals but is a late-surviving member

172 ted for the same orthologous region in three marsupial (North American opossum, South American opossu

173 Marsupials occupy a diverse range of habitats, which may

174 al mammalian lineages (primates, chiropters, marsupials), one amphibian and one flatworm, the planari

175 The gene identified in the South American marsupial opossum and dubbed syncytin-Opo1 has all of th

176 re conducted in the primitive South American marsupial opossum, Monodelphis domestica.

177 s tropicalis, the monotreme platypus and the marsupial opossum, to gain further insight into possible

178 s in the full spectrum of mammals, including marsupial (opossum) and monotreme (platypus), but not in

179 e, guinea pig, rabbit and armadillo, and one marsupial, opossum.

180 Our phylogenetic analysis indicates that marsupials or their closest relatives evolved in North A

181 t the syntenic genomic locus in metatherian (marsupial) or prototherian (monotreme) mammals.

182 g strategy we previously identified fourteen marsupial- or species-specific microRNAs in the marsupia

183 Although marsupial orthologs of protein-coding exons were easily

184 verage 55% greater than that seen with human-marsupial pairs.

185 The presence of specialized marsupial patterns of tooth replacement and cranial vasc

186 Marsupials, placentals and their close therian relatives

187 de of Laurasian continents, including extant marsupials, placentals and their relatives.

188 As in marsupials, platypus TCRmu is expressed in a form contai

189 Although it has been claimed that marsupials possess a lower density of isocortical neuron

190 a Buzinie amber (France), preserved with its marsupial pouch and content.

191 We show that as marsupial predators in Australia, South America, and Pap

192 In marsupials, pregnancy is relatively short, and although

193 primitive metatherian mammals (relatives of marsupials), previously thought to have become extinct d

194 million years ago and extends the record of marsupial relatives with skeletal remains by 50 million

195 diversity of color vision systems present in marsupials remains mostly unexplored.

196 Marsupials represent a less constrained condition, demon

197 s the most extensively used, laboratory-bred marsupial resource for basic biologic and biomedical res

198 e orthologous sequence from platypus and the marsupials, respectively; these numbers are distinctly l

199 aterally at an early stage of development in marsupials resulted in normal spatial relationships betw

200 alysis of 54 unique V(H) sequences from this marsupial revealed the presence of two V(H) families in

201 the 57 GenBank sequences and including eight marsupial sequences would allow us to identify regions u

202 ized to the X in all the eutherians, but not marsupial, so it must have been added to the X 80-130 mi

203 n the X chromosome in all species, including marsupials, so it was part of the ancient X.

204 tein analyses presented here in chicken, two marsupials (South American opossum and tammar wallaby),

205 f cortical surface area in three diprotodont marsupial species (two macropodiformes, the red kangaroo

206 e alignable sequences between human and each marsupial species are not completely overlapping (only 8

207 supial- or species-specific microRNAs in the marsupial species Monodelphis domestica.

208 per unit of cortical surface area in several marsupial species overlap with those found in eutherian

209 ation data from two other, distantly related marsupial species, suggests that reduced female recombin

210 sequences from two nocturnal South American marsupial species, the gray short-tailed opossum, Monode

211 ion, we have studied the rod pigments in two marsupial species, the nocturnal and frugivorous bare-ta

212 sentative eutherian species and at least one marsupial species.

213 hin the germline of numerous closely related marsupial species.

214 As the first metatherian ('marsupial') species to be sequenced, the opossum provide

215 trate that half of these miRNAs evolved from marsupial-specific transposable elements.

216 2 kb long, that has been found in ruminants, marsupials, squamates, monotremes, and African mammals.

217 3 gene pairs, suggesting that eutherian and marsupial Stratum 2 genes may have been independently re

218 hat mAAV-EVE1 occurs specifically within the marsupial suborder Macropodiformes (present-day kangaroo

219 Comparisons between eutherians and marsupials suggest limited conservation of the molecular

220 the first genomic scale structural detail of marsupial TCR genes, a lineage of mammals used as models

221 he recent discovery of a unique TCR chain in marsupials, TCRmu, raises questions about its possible r

222 lationship to metatherians (including extant marsupials) than to eutherians (including extant placent

223 tailed opossum (Monodelphis domestica), is a marsupial that is proposed to represent this ancestral s

224 rt-tailed opossum), a nocturnal, terrestrial marsupial that shared its last common ancestor with plac

225 papillomas and carcinomas in the endangered marsupial the western barred bandicoot (Perameles bougai

226 trast, M6P/IGF2R is imprinted in a didelphid marsupial, the opossum, but it strikingly lacks the diff

227 y areas of the neocortex of a South American marsupial, the short-tailed opossum (Monodelphis domesti

228 in other species, the lemur, the cat, and a marsupial, the tammar wallaby.

229 s end, we have cloned SF1 from an Australian marsupial, the tammar wallaby.

230 Although most were marsupials, the list includes the large, flightless mihi

231 Among marsupials, the most robust clade includes all orders ex

232 ocortex was investigated in three species of marsupials, the northern quoll (Dasyurus hallucatus), th

233 ether M. domestica is unique or the norm for marsupials, the V(H) and V(L) of an Australian possum, T

234 ut 170 million years ago (i.e., primates and marsupials), therefore implicating these sites as candid

235 Rather, marsupial V(H) and V(L) complexity appears to be evolvin

236 All marsupial V(H) sequences isolated so far form a common c

237 Homo or Trichosurus vulpecula (an Australian marsupial), we show that metatherian X chromosomes have

238 Here we show that some marsupials-which are the closest living relatives to eut

239 Monodelphis is a small pouchless marsupial whose young undergo a protracted period of pos

240 emorphia) are a unique order of Australasian marsupials whose sparse fossil record has been used as p

241 so we were interested in comparing SF1 of a marsupial with that of eutherians.

242 the tree shrew, is similar to that found in marsupials, with uncrossed axons confined to lateral reg

243 d at three widely separated sites and in the marsupial wombat.

244 reexamination of the female somatic inactive marsupial X chromosome reveals that it does share common

245 In female marsupials, X chromosome inactivation (XCI) is imprinted

246 To study the phenomenon of marsupial XCI more comprehensively, we profiled parent-o

247 In addition to recently reported evidence of marsupial XCI regulation by the noncoding Rsx transcript