ライフサイエンスコーパス: masculinization

1 th grey and white matter, suggesting neural 'masculinization'.

2 red a concomitant development to ensure male masculinization.

3 conditional deletion of Ihh inhibits penile masculinization.

4 nce testosterone production for hypothalamic masculinization.

5 rogramming by fetal androgen exposure during masculinization.

6 POA and whether they influence developmental masculinization.

7 testosterone production by fetal LC to drive masculinization.

8 is ultimately determined by androgen-induced masculinization.

9 ing the pathway of steroid-independent brain masculinization.

10 tivity lead to varying degrees of defects in masculinization.

11 ed that increased GABA neonatally results in masculinization.

12 to C. elegans caused only very weak, if any, masculinization.

13 n is essential for normal reproductive tract masculinization and has highlighted that measuring AGD i

14 astrocytes are also critical contributors to masculinization and illustrate the importance of nonneur

15 yperandrogenism and is an important cause of masculinization and infertility in women.

16 signaling prevents PGE(2)-induced behavioral masculinization and whether activation of glutamate rece

17 function, such as Menidia, feminization and masculinization are equally detrimental.

18 ebra finch, steroids that impact song system masculinization are most likely not synthesized from the

19 nalysis of the quantitative genetic basis of masculinization, as indicated by the anogenital distance

20 The masculinization, but not the suppression of XO lethality

21 xposed to endocrine disrupters, specifically masculinization by exposure to androgens and feminizatio

22 Measures of behavioral masculinization correlate with a twofold increase in spi

23 ren born with congenital genitourinary tract masculinization disorders by array-comparative genomic h

24 tive urogenital traits observed in boys with masculinization disorders such as cryptorchidism, urethr

25 es to dibutyl phthalate (DBP), which induces masculinization disorders, dose-dependently prevented th

26 strongly androgenic, thereby explaining the masculinization effects.

27 re is family-specific and typically leads to masculinization (female-to-male sex reversal), resulting

28 each male and female is a mosaic of relative masculinization, feminization, and sameness, which theor

29 othesis that either prenatal feminization or masculinization hormone influences in utero or later soc

30 , such as sel-10(n1074), cause a more severe masculinization, including a reversal of the life versus

31 tional prostaglandin synthesis prevents this masculinization, indicating a positive feedforward proce

32 This masculinization is associated with transmission of the S

33 Additionally, masculinization is generally more detrimental to populat

34 Although masculinization is well studied, no unifying concept exp

35 ed FSD emerged only recently and that female masculinization may be the ancestral lemur condition, an

36 We conclude that masculinization might constitute an alternative mechanis

37 Prostaglandin E(2) (PGE(2)) mediates the masculinization of adult sex behavior in rats in respons

38 anti-androgens or androgens and showed that masculinization of all reproductive tract tissues was pr

39 Ht31 does not prevent the masculinization of behavior by ACPD plus kainate cotreat

40 mined that PKA signaling is required for the masculinization of behavior by PGE(2).

41 PGE(2), EP(2) and EP(4) are required for the masculinization of behavior by PGE(2).

42 54 myosin heavy chain promoter caused strong masculinization of both C. briggsae and C. elegans herma

43 s, including suppression of XO lethality and masculinization of both XX and XO animals.

44 ne during early development is necessary for masculinization of brain structures in rodents.

45 The masculinization of DE in OS female twins is unlikely to

46 differences in microglia, estradiol-induced masculinization of dendritic spine density, and adult co

47 r with the finding of rapid androgen-induced masculinization of female vocalizations, provides an inv

48 Androgen-driven masculinization of females was also confined to the same

49 to oogenesis at 25 degrees C, resulting in a masculinization of germline (Mog) phenotype.

50 Loss of sel-10 results in a mild masculinization of hermaphrodites, whereas dominant alle

51 event downstream of Sry that is critical for masculinization of mammalian embryos.

52 Thus, masculinization of MePD astrocytes is a result of both A

53 al androgen receptors (ARs) are required for masculinization of MePD astrocytes, as these measures ar

54 Moreover, the genetic masculinization of neurons in an otherwise wild-type her

55 in the sex-determining gene tra-3 results in masculinization of somatic tissues, consistent with QKI-

56 e two signaling pathways interact to control masculinization of the brain and behavior remains to be

57 Biological factors, such as the masculinization of the central nervous system by prenata

58 ell differentiation, testis morphogenesis or masculinization of the embryos.

59 androgen receptor (AR) gene cause incomplete masculinization of the external genitalia by disrupting

60 We show here that mag-1(RNAi) causes masculinization of the germ line (Mog phenotype) in RNA-

61 S exposure is likely to pose minimal risk to masculinization of the human fetus.

62 differences primarily arose due to hormonal masculinization of the male brain (and to a lesser exten

63 rogen receptors (ERs) alone mediate prenatal masculinization of the mouse brain to organize reproduct

64 or activation has been shown to be vital for masculinization of the rodent brain, our results indicat

65 These results suggest that masculinization of the song system is not determined sol

66 ogen receptor (AR) mRNA were measured, since masculinization of the song system is, in part, accompli

67 Adult androgen exposure can induce partial masculinization of the syrinx, but other factors must be

68 46XX females can result in vaginal atresia, masculinization of the urethra, a single urogenital sinu

69 Lack of Wnt4 gives rise to masculinization of the XX gonad and we showed previously

70 led to feminization of the X chromosome and masculinization of the Y chromosome.

71 The masculinization of these cells is independent of AR but

72 xists for both AR and SNX2 to be involved in masculinization of these two brain regions.

73 Selective masculinization of third-order neurons transforms their

74 tions at the perineum play a crucial role in masculinization of this neural system.

75 ice, a targeted deletion of Wnt-4 causes the masculinization of XX pups.

76 his sex steroid receptor is associated with "masculinization" of adolescent cortical maturation.

77 gross changes in general behaviour, and (4) 'masculinization' of FruM-expressing neurons in females i

78 nt stages of X differentiation, resulting in masculinization or demasculinization of the X-chromosoma

79 it unlikely that in utero femininization or masculinization or socialization effects of growing up w

80 sent genetic evidence that the sel-10(n1074) masculinization phenotype is dependent upon skr-1 and cu

81 ound resulted in a highly penetrant germline-masculinization phenotype.

82 versing treatment itself interfered with the masculinization process, or that a male genome is requir

83 ar to androgen production/action during the 'masculinization programming window' (MPW; e15.5-e18.5).

84 t androgen production/action during a fetal 'masculinization programming window'.

85 to propose that the natural process of brain masculinization puts males at risk by moving them closer

86 Disorders of fetal masculinization, resulting in hypospadias or cryptorchid

87 neural development generally and song system masculinization specifically.

88 ch activates two processes in male neonates; masculinization, the development of male-type behaviors,

89 the innate immune system in directing brain masculinization, the evidence for which we review here.

90 n is maintained by the active suppression of masculinization via DNA methylation.

91 s that implicates (as a putative mechanism) 'masculinization' via androgen exposure; however, relativ

92 of dying out but with less extreme pressure, masculinization will not be detectable since the proport

93 of both phenotypic and genetic components in masculinization with effects being greater in females.