ライフサイエンスコーパス: massive

1 The existence of massive (10(11) solar masses) elliptical galaxies by red

2 Here we show that the massive 2014-2015 fissure eruption in Holuhraun, Iceland

3 iciency virus, despite high viral levels and massive ablation of pulmonary CD4(+) T cells.

4 Atg5 led to higher levels of C99 and to its massive accumulation in the lumen of enlarged perinuclea

5 Cs showed altered replication fork dynamics, massive accumulation of DNA damage, genome-wide double-s

6 and co-deletion of DNase1L2 and Trex2 causes massive accumulation of DNA fragments throughout the cor

7 els of SIV infection in SLOs occurred with a massive accumulation of infiltrated MAC387(+) macrophage

8 20 enhanced extramedullary hematopoiesis and massive accumulation of myeloid-derived suppressor cells

9 scovered that lymphocyte activation triggers massive acetylation of chromatin.

10 lar proliferation in a synergistic manner by massive activation of intrinsic apoptosis.

11 nt activation, those in clusters 1 and 2 had massive activation of the alternative pathway, including

12 nts of high pressure metamorphic rocks imply massive addition of subducted N to the mantle and past t

13 We describe similar massive adipose overgrowth with suppressed leptin expres

14 However, only Podo-GC-A KO mice developed massive albuminuria (controls: 35-fold; KO: 5400-fold ve

15 Previously we demonstrated massive albuminuria with hypertension in uninephrectomiz

16 es, bacterial-algal interactions, control of massive algal blooms in the ocean, and the maintenance a

17 Massive all-atom molecular dynamics simulations were con

18 ecretion of chloride, likely responsible for massive alteration in mucus phenotype.

19 um, the cytoplasmic organelle that matures a massive amount of nascent secretory polypeptides, is par

20 As a result, our nanosystem can capture massive amounts of data every second, store it directly

21 ptor cilium has an innate ability to release massive amounts of ectosomes.

22 raphic investigation led to the discovery of massive amounts of intracardiac air which demanded urgen

23 e on the surface of the root cap and secrete massive amounts of mucilage that contains polysaccharide

24 ed that disease emergence was accompanied by massive amplification in the normally sparse, afferent s

25 Brown dwarfs are massive analogs of extrasolar giant planets and may host

26 ed in roots of ARD affected plants employing massive analysis of cDNA ends (MACE) and RT-qPCR.

27 e heart beat require this calcium flow to be massive and fast.

28 two new members have joined the consortium: MassIVE and jPOST.

29 n silicon nanowires yields dopant-dependent, massive and ordered 3D grooves with spacing down to 5 n

30 ities are becoming more prominent, with both MassIVE and PeptideAtlas releasing the results of reproc

31 the metastatic transition is accompanied by massive and recurrent alterations in enhancer activity.

32 on of human microglia/macrophages results in massive apoptosis, a small population of HIV-infected ce

33 Mechanosensory afferents of the massive array of chordotonal organs (Johnston's organ) o

34 , culminating in karyotypic alterations with massive arrays of telomere fusions.

35 he formation of whole chromosomes containing massive arrays of telomeric fusions indicative of multip

36 for arbitrary control of individual pens in massive arrays.

37 only body mass index, liver iron deposition, massive ascites, and use of 3.0 T were significantly ass

38 Massive ascites, iron deposition, and high body mass ind

39 sis, body mass index, liver iron deposition, massive ascites, use of 3.0 T, presence of cirrhosis, an

40 logy of various human diseases has attracted massive attention in the last decade.

41 50-day period surrounding either moderate or massive auditory nerve damage.

42 of benign heterozygous variants that act as massive background noise (typically, in a 400:1 excess r

43 in from ischemic cerebral microvessels and a massive BBB leakage at 4.5-hour post-ischemia.

44 The identified massive biclusters can be used to develop improved trans

45 These massive biological structures, which can be seen from sp

46 Massive biotic change occurred during the Eocene as the

47 The origin of super-massive black holes in the early universe remains poorly

48 ry connection between stellar-mass and super-massive black holes.

49 y autopsy, of lichenoid esophagitis in which massive bleeding from generalized epithelial sloughing a

50 tigate the most iconic among these features: massive boulders atop a cliff in North Eleuthera, Bahama

51 of caspase (SMAC) mimetic treatment induced massive cell death and led to regression of tumors.

52 We also found massive cell death in the oriens layer of the hippocampu

53 ogression that leads from the HD mutation to massive cell death in the striatum is the ability to cha

54 Massive cell death occurs in cultured neurons upon deple

55 Side-by-side comparisons confirmed massive cell death, before synaptogenesis, within 1-4 DI

56 filamentous bacteria Streptomyces undergo a massive cell division event in which the synthesis of la

57 alth workers, and patients in war zones is a massive challenge, but crucial to understanding the exte

58 sms exist in regulation of host responses to massive challenges from microbiota to maintain immune ho

59 s into fully differentiated neurons requires massive changes in epigenetic and transcriptional states

60 activation of the chloroplast and generates massive changes in the nuclear gene expression required

61 aminar optic nerve invasion, or combined non-massive choroidal and prelaminar/laminar optic nerve inv

62 ert their anticancer activities by producing massive chromosome aneuploidy.

63 These massive compendia comprise billions of measurements and

64 Rather than focusing on massive computation of many different examples of a sing

65 on of membrane dynamics and does not require massive computational overhead to model the solvent.

66 Through its massive cost reduction and usability we anticipate that

67 If intensification is not successful and massive cropland land expansion is to be avoided, SSA wi

68 ve lymphocyte activation could contribute to massive cytokine production, known to mediate tissue dam

69 ve lymphocyte activation could contribute to massive cytokine production, known to mediate tissue dam

70 hough the underlying mechanisms are unknown, massive cytokine secretion is thought to be involved.

71 The massive data generated by these techniques together with

72 apply large-scale Gaussian mixture models to massive datasets using Hadoop.

73 Recent massive decline in aspen-dominated forests and an increa

74 al ventricle (LV) walls is associated with a massive decline of the proliferative capacities of the s

75 ecies and the bacteria were shown to display massive decreases in population size, in contrast to pat

76 (Nicotiana tabacum) 'Bright Yellow-2' cells: massive delivery of preexisting vesicles to a disk-shape

77 ition within the local circuit generates the massive dentate gyrus circuit hyperactivation evident in

78 mary target cells for SIV/HIV infection, and massive depletion of these cells is considered a major c

79 ianaCA-MPK3 plants are dwarfed and display a massive derepression of defense genes associated with sp

80 Massive digitization efforts have the potential to great

81 We exploit the property that massive Dirac fermions form mid-gap bound states with sp

82 Perplexingly, these massive discharge events-Heinrich events-occurred during

83 ted in precancerous pancreases, which induce massive DNA damage, including DNA double-strand breaks.

84 urface heating of sediment creates short and massive DOC discharge events that elevate the bottom-wat

85 in this megaherbivore despite possession of massive dorsal and lateral armor, illustrating a signifi

86 Nepal was struck by a massive earthquake on the 25th April 2015 and major afte

87 l particulate steroids have an immediate and massive effect on microvascular perfusion because of for

88 vated patients selected for clinical trials, massive efforts using this approach have failed to achie

89 nd heterogeneous at the molecular scale, and massive electronic excitations are produced as a result

90 then they can account for the population of massive elliptical galaxies at z approximately 4 in term

91 of depleted stellar density in the cores of massive elliptical galaxies extends over the same radius

92 etroduplication has played key roles for the massive emergence of NLR genes including functional dise

93 behavior of adult animals despite triggering massive end-to-end chromosome fusions across the brain.

94 This massive endosomal influx was accompanied by dramatic rec

95 starch, but is obliterated by expansion of a massive endosperm, where all embryo-nourishing reserves

96 at a limited number of genes associated with massive enhancer regions.

97 This response is typified by massive eosinophilia, and we were able to confirm pyropt

98 y inflammation after allergen exposure, with massive eosinophilic lung infiltrates and increased Th2

99 lls, including neural stem cells, experience massive errors in mitosis, leading to increased cell dea

100 geologic history by ubiquitous and sustained massive eruption of lava, forming several enormous igneo

101 ed to the region of partial melt feeding the massive eruption.

102 Extensive fallout from these massive eruptions has been found >2,800 km from Mount Ta

103 Our results suggest that massive EV/exRNA uptake would be required to ensure func

104 ne-exon gene structure that have undergone a massive expansion in ants and other eusocial insects.

105 PHIP had extensive lymphocytosis marked by massive expansion of natural killer (NK) and T cell comp

106 In the present study, we show massive expansion of NK and T cell compartments during t

107 Despite massive fluctuations in its internal triglyceride conten

108 sine-like SphK1 inhibitors induced rapid and massive formation of vesicles in diverse cell types that

109 chondrial in a cell, collectively) involving massive fusion and membrane biogenesis to form a perinuc

110 Recent observations have revealed massive galactic molecular outflows that may have the ph

111 Finding massive galaxies that stopped forming stars in the early

112 st three billion years old, half of the most massive galaxies were extremely compact and had already

113 /- 0.11, this galaxy is the most Mg-enhanced massive galaxy found so far, having twice the Mg enhance

114 formation games, the private information and massive game tree have made no-limit poker difficult to

115 e of these distinct cell fates are driven by massive gene expression programs that promote the necess

116 capacity of developmental systems, allowing massive genetic perturbations to be channeled toward ord

117 present, the analysis of multi-dimensional, massive genome-wide data requires an initial pruning ste

118 ore, Balaur can enable institutions handling massive genomic data sets to shift part of their analysi

119 software platform for storing and analyzing massive genomic datasets.

120 Our results suggest coincidence of massive genomic DNA losses and increased power of geneti

121 ococcus) is a human pathogen, accounting for massive global morbidity and mortality.

122 contact metamorphism, likely liberating the massive greenhouse gas volumes needed to drive extinctio

123 iltration, ciliary body/muscle infiltration, massive (>/=3 mm) choroidal invasion, retrolaminar optic

124 ecord (EHR) systems has led to collection of massive healthcare data, which creates oppor- tunities a

125 at may offer new hope for patients suffering massive heart attacks.

126 onary disease (COPD), who presented with non-massive hemoptysis.

127 than 1:2 ratio transfusion in the setting of massive hemorrhage may not be appropriate for all patien

128 iency, in vivo cholesterol challenges induce massive hepatic cholesterol accumulation and damage, whi

129 A computed tomographic scan revealed massive hepatomegaly caused by multiple cysts of variabl

130 main factors: first, a large fraction of the massive high-redshift galaxy population was strongly bar

131 proposed dams, if constructed, will trigger massive hydrophysical and biotic disturbances that will

132 observed in the Sahel region at the time of massive iceberg surges, leading to large freshwater disc

133 ausing a severe inflammatory phenotype, with massive immune cell infiltrates already before birth.

134 active T cells in the periphery, resulted in massive immune cell recruitment into the affected forebr

135 We observed massive impacts on a marine assemblage, with near doubli

136 The massive improvement in performance is due to the strong

137 The degree of TR was severe or massive in 88% of patients before the procedure.

138 HEK293T cells expressing alpha-syn, causes a massive increase in alpha-syn aggregation.

139 in late infancy, events that coincide with a massive increase in overall synaptic drive.

140 The massive increase in recombination observed in recq4 figl

141 The massive increase in the number of tasks when running an

142 rbons to include both C10 and C13 leads to a massive increase in the PKIE for COX oxygenation of AA.

143 When skin is injured, there is a massive increase of heat shock protein (Hsp) 90alpha ins

144 n which water vapour leads to a trapping and massive increase of particulate matter in the near-surfa

145 ed intense lung inflammation coincident with massive increases in proinflammatory proteins and IFN-al

146 We observe massive induction of transcriptional readthrough, both i

147 , which is mainly driven by inflammation and massive infection by the virus.

148 severe inflammation is mediated, in part, by massive infiltration and sequestration of hyperactive ne

149 ike non-inflamed, normal skin in the face of massive inflammatory changes in nearby affected skin.

150 Myocardial infarction (MI) elicits massive inflammatory leukocyte recruitment to the heart.

151 These high temperatures, together with a massive injection of water, which is a source of odd-hyd

152 ory stimuli prepares the body against future massive insult by activating endogenous protective respo

153 rigenesis, Apc(min/+) mice, which succumb to massive intestinal polyposis, were bred to Ctbp2(+/-) mi

154 Autopsy demonstrated a massive intrasinusoidal infiltration of the liver by bre

155 emography and natural selection in promoting massive introgression are difficult to assess and an imp

156 sed by an A. gambiae-like sex chromosome and massive introgression of A. coluzzii autosomal alleles.

157 even low levels of interbreeding can lead to massive introgression of local alleles into an invader's

158 NA barcoding of tropical insects reared by a massive inventory suggests that the presence of cryptic

159 This massive iron flux must be precisely controlled to permit

160 2-Cre;Bmp2(fl/fl) (Bmp2(LSECKO)) mice caused massive iron overload in the liver and increased serum i

161 erium for hydrogen has been shown to lead to massive kinetic isotope effects (KIE) for soybean lipoxy

162 were not detected at 24 hours after injury, massive leukocyte infiltration was observed in the super

163 hrough a "design-build-test" cycle paradigm, massive libraries of genetically engineered microbes can

164 approximately 90% transferrin saturation and massive liver iron overload, whereas Smad1(fl/fl);Smad5(

165 and that they ultimately grew into the most massive local elliptical galaxies seen today, through me

166 However, massive loss of genomic DNA in these lineages often occu

167 in the cellular microenvironment leading to massive loss of neuronal populations and increased neuro

168 tely, primary HIV-1 infection results in the massive loss of these cells within weeks of infection, w

169 rtality rates in newborn piglets, leading to massive losses to the swine industry worldwide during re

170 We suggest that both massive lymphocytosis and excessive lymphocyte activatio

171 Both massive lymphocytosis and excessive lymphocyte activatio

172 The massive lymphocytosis could be the result of nonadapted

173 PIKfyve inactivation causes massive lysosome swelling, disrupts membrane recycling,

174 As it progresses, the massive macromolecular catabolism dismantles the chlorop

175 reduction in nitrogen inputs, representing a massive management challenge.

176 laser cooling experiments continue to bring massive mechanical systems to unprecedentedly low temper

177 found that treatment with anle138b leads to massive melanoma cell death due to a major dysregulation

178 bation and PtdIns(3,5)P2 reduction result in massive membrane vacuolation along the endosomal system,

179 , challenging our textbook depiction of this massive membrane-embedded complex.

180 Compound exocytosis is considered the most massive mode of exocytosis, during which the membranes o

181 The event caused coral bleaching and massive mortality of corals and other reef-associated or

182 electron microscopic imaging we demonstrated massive movements of calsequestrin accompanied by drasti

183 sion and species replacement likely promoted massive mtDNA introgression.

184 HIT'nDRIVE may help clinicians contextualize massive multiomics data in therapeutic decision making,

185 e characterized by systemic inflammation and massive muscle and adipose tissue wasting.

186 could be easily extended to the analysis of massive networks.

187 cute inflammatory pathology characterized by massive neutrophil influx leading to edema and hemorrhag

188 aterials within Eridania are thick (>400 m), massive (not bedded), mottled deposits containing saponi

189 o pre-define the division plane [5-8]; then, massive nuclear export of the anillin-like protein Mid1

190 ccess but proved to be unfeasible due to the massive number of alternative models, so genetic program

191 DeltasagA mutant infection sites had massive numbers of and few intact neutrophils at the edg

192 eltasse DeltasagA mutant infection sites had massive numbers of intact neutrophils throughout the who

193 ration of novel complex structures following massive ontogenetic perturbation.

194 hours of mixing, leading to the formation of massive OPA clusters.

195 so that they contribute to the formation of massive OPAs of smaller oil droplets (< approximately 5-

196 In light of the massive OR expansion in ants ( approximately 400 genes p

197 mortality is restricted to patients who have massive or submassive PEs.

198 vidence is very limited and pertains only to massive osteochondral surgery for trauma or malignancy,

199 The massive outbreak of Ebola virus disease in west Africa b

200 eed, several recent models predict that such massive outflows may ignite star formation within the ou

201 In addition, a massive overrepresentation of members of the luciferase-

202 analysis approach to organize and interpret massive pairwise syntenic relationships.

203 bsence of SEC23B die perinatally, exhibiting massive pancreatic degeneration.

204 All variants were identified with massive parallel sequencing and confirmed with Sanger se

205 SL-seq is therefore ideal for fast and massive parallel sequencing of parasite transcriptomes d

206 iple-simultaneous drug administration, and a massive parallel testing of drug response.

207 Next-generation massive-parallel DNA sequencing (NGS) analysis did not d

208 Dual segmentation allows for massive parallelization, which lifts the scaling ceiling

209 e artificial gravitational force acting on a massive particle: exciton-polariton.

210 catheter-directed therapy for submassive and massive PE and gives representative examples that reflec

211 tion, rationale for stratification, imaging, massive PE management and outcomes, submassive PE manage

212 re limited by the tools to analyze fully the massive phenotype data, especially the dynamic relations

213 Because they are intended to be applied to massive population level data, it is essential that the

214 00-3,550 years ago, coinciding with recorded massive population movements in Mesopotamia during the m

215 Gravitational collapse of a massive primordial gas cloud is a promising initial proc

216 In nematodes, osmotic stress induces massive protein aggregation coupled with unfolded protei

217 anied by attenuation of protein translation, massive protein aggregation, growth arrest, and lethalit

218 Poly ADP-ribose polymerases (PARPs) catalyze massive protein poly ADP-ribosylation (PARylation) withi

219 Nephrotic syndrome is characterized by massive proteinuria and injury of specialized glomerular

220 ier becomes excessively permeable leading to massive proteinuria.

221 archers to rapidly access and collaborate on massive public cancer genomic datasets, including The Ca

222 sources below 100 degrees C is available in massive quantities around the world, but cannot be conve

223 ughput genomics technologies has resulted in massive quantities of diverse omics data that continue t

224 These surveys have revealed the presence of massive, quiescent early-type galaxies appearing as earl

225 However, these early, massive, quiescent galaxies are not predicted by the lat

226 ys have reported evidence for populations of massive, quiescent galaxies at even higher redshifts and

227 nthesize the nucleotides (p)ppGpp, causing a massive re-programming of the transcriptional profile kn

228 These rearrangements lead to a massive recruitment of keratinocytes from the adjacent e

229 s in vivo Pdx1(DeltaAREAII/-) mice exhibit a massive reduction in endocrine progenitor cells and prog

230 Following polyploidy events, genomes undergo massive reduction in gene content through a process know

231 In spite of the persistent and massive reduction of LT-HSCs, steady-state hematopoiesis

232 sosomal pH dysregulation has been described, massive reduction of lumenal chloride is observed that i

233 These massive regions extend approximately 1,000 kilometres up

234 volatile and Cl-rich SLIP lavas, permitted a massive release of nickel-rich volcanic gas and subseque

235 e outbreak of inflammation, accompanied by a massive release of proinflammatory cytokines at the mate

236 ystemic inflammation, which results from the massive release of proinflammatory molecules into the ci

237 The amphibian olfactory system undergoes massive remodeling during metamorphosis.

238 We also observe massive removal of thousands of genes related to the tra

239 five families presenting late-onset NPH with massive renal fibrosis.

240 f nucleocytosolic acetyl-CoA production with massive reorganization of the transcriptome and respirat

241 tween competing hypotheses, we constructed a massive repository of historical and archaeological info

242 Uncultivated bacteria represent a massive resource of new enzymes and bioactive metabolite

243 uantifying known lncRNAs is not trivial from massive RNA-seq data.

244 al crown development, adventitious roots and massive root mounds, leading to multi-stemmed trees with

245 One fetus died; the other two had transient massive salt-wasting and polyuria reminiscent of antenat

246 ing common and is now being implemented on a massive scale by projects such as the Human Cell Atlas.

247 We use molecular dynamics simulations on a massive scale to elucidate the structural ensemble of ag

248 A massive scale-up of rapid diagnosis and treatment is nec

249 ssue states but can be costly to generate at massive scale.

250 novel neural recording technique, promising massive-scale, single-cell resolution monitoring of larg

251 w compressive modalities as a foundation for massive scaling in high-throughput measurements and new

252 However, the massive sequence data and the diverse properties of diff

253 rect role of EP in protein-DNA binding using massive sequencing data.

254 sequencing techniques became affordable for massive sequencing efforts devoted to clinical character

255 ar mechanisms of GAS virulence, coupled with massive sequencing efforts to isolate genomes, have allo

256 Through massive shotgun sequencing of circulating cell-free DNA

257 Here we performed massive single-genome, near-full-length next-generation

258 Massive slums have become major features of cities in ma

259 After massive small bowel resection, tuft cells and Tm were di

260 Massive somatic mutations discovered by large cancer gen

261 ic aneurysms of the right hepatic artery and massive splenic infarction as rare complications of Stre

262 Rather, inhibition of ATP synthesis caused massive spontaneous vesicle exocytosis, followed by arre

263 The massive star ends its life with a catastrophic collapse

264 bsorbers have physical properties similar to massive star-forming galaxies and are embedded in enrich

265 n of disk radius) for the outer disks of six massive star-forming galaxies, and find that the rotatio

266 n imaging shows it to be a pair of extremely massive star-forming galaxies.

267 The dpe2-1/phs1a/ss4 mutant revealed a massive starch excess phenotype.

268 echanism for the violent ejection of mass in massive stars may be required.

269 ucture formation, the precursors of the most massive structures in the Universe began to form shortly

270 ides TWIP and TRIP, such alloys benefit from massive substitutional and interstitial solid solution s

271 Despite massive success of shale gas production in the US in the

272 in the form of plume particles and seafloor massive sulfide structures.

273 The early formation of such massive systems implies that our picture of early galaxy

274 ploration of quantum physics in larger, more massive systems.

275 ic shock syndrome, which is characterized by massive T cell activation and a predominant Th1 profile

276 Massive technological advances enabled high-throughput m

277 coalescing pair of "heavy" black holes (more massive than [Formula: see text] M[Formula: see text]) l

278 .5 billion solar masses of dust, and is more massive than any other known object at a redshift of mor

279 ts depends on the mass of the lens: the less massive the lens, the shorter the microlensing event.

280 patients, thereof 4% that were reduced from massive to severe.

281 and upon signaling to the nucleus initiate a massive transcriptional reprogramming critical to mount

282 There were 865 massive transfusion events that occurred within 4 years,

283 ut trauma, who account for nearly 90% of all massive transfusion events.

284 nfluence of traumatic brain injury (TBI) and massive transfusion on fibrinolysis status.

285 ced resuscitation has become integrated into massive transfusion practice, there is a paucity of evid

286 Massive transfusion was defined as the transfusion of at

287 bleeds were the most common indications for massive transfusion.

288 This study is a retrospective review of all massive transfusions provided in an urban academic hospi

289 All patients who received massive transfusions within the study period and survive

290 osymbionts into cell organelles involved the massive translocation of genetic material from the organ

291 inflammatory bowel disease characterized by massive transmural influx of leukocytes and lymphocytes,

292 from 2005 to 2010, a period characterized by massive treatment expansion.

293 The 2011 East Japan earthquake generated a massive tsunami that launched an extraordinary transocea

294 e transcriptional signatures that define the massive, underground storage roots used as a food source

295 mucosal sloughing severe enough to result in massive upper gastrointestinal bleeding and death.

296 The massive use of fossil fuels during the last 50 years has

297 underlies loss of synaptic transmission via massive vesicle release and subsequent failure to endocy

298 vere droughts over North America have led to massive water shortages and increases in wildfire freque

299 asekhar-mass white dwarf merging with a less-massive white dwarf.

300 With the availability of massive whole genome sequencing data, it becomes practic