ライフサイエンスコーパス: massively

1 Transposons are massively abundant in all eukaryotic genomes and are sup

2 SF signaling, surfactant-exposed macrophages massively accumulated cholesterol ester-rich lipid-dropl

3 n mice, monocyte-derived macrophages (MoMFs) massively accumulated in injured liver within 12-24 hour

4 Furthermore, we reveal that PSTVd infection massively activates genes involved in plant immune respo

5 cts in adherens junctions components in mice massively affects progenitor cell proliferation and lead

6 of the MSY's genes belong to three acquired, massively amplified gene families that have no homologs

7 resulting cell line (EndoC-betaH2) could be massively amplified in vitro.

8 gambiae Y consists almost entirely of a few massively amplified, tandemly arrayed repeats, some of w

9 We found that all lineages of mangroves massively and convergently reduce TE loads in comparison

10 nd Thailand and show that these cells expand massively and express phenotypes indicative of overwhelm

11 ponse to Salmonella typhimurium (STm) occurs massively at extrafollicular sites, without notable germ

12 is of a prospective, observational cohort of massively bleeding patients.

13 lls mount rapid TGN1412 responses, which are massively boosted by FcgammaR crosslinking, in particula

14 nduced activation of the PI3K/Akt pathway is massively compromised in SPPL2a(-/-) B cells and identif

15 e the information capacity of the network is massively compromised.

16 of neurons in a prefrontal gaze control area massively converge towards the saccadic target.

17 scribe a novel biclustering algorithm called Massively Correlated Biclustering (MCbiclust) that selec

18 In this study, we found that nucleosomes are massively depleted from the active rDNA genes during log

19 1 infection, gut T-helper (Th) 17 cells are massively depleted leading eventually to compromised int

20 ved only within myeloid cells in tissues not massively depleted of CD4(+) T cells.

21 seed maturation and reserves such as oil are massively deposited in the enlarging embryo.

22 e cardiac interstitium during embryogenesis, massively differentiate into CFs after MI.

23 lated the growth of lesions, which exhibited massively dilated glands with a flattened layer of strom

24 hway techniques and Markov state model-based massively distributed simulations for mapping the confor

25 agreement with time-resolved experiments and massively distributed, ensemble-convergent molecular-dyn

26 Thus, chronic HCV infection massively disturbs the B-cell compartment even in patien

27 that the subventricular zone (SVZ) expanded massively during the early second trimester, becoming de

28 by developing neural cells and results in a massively enlarged brain composed of neuroblasts with ne

29 nt human fibroblasts, the Golgi apparatus is massively enlarged, which is in line with the concept th

30 High-frequency mutations are found to be massively enriched in microbial colonies compared with w

31 vels in cells dividing at a high rate but is massively evicted in cells undergoing their last cell cy

32 loss in aGVHD patients is 190 bp/wk, thereby massively exceeding physiological steady-state TL shorte

33 A method is described to massively expand bone marrow-derived basophils in vitro.

34 and organismal biology are clearly poised to massively expand.

35 rus (ERAV), together with the structure of a massively expanded ERAV particle, each at approximately

36 helial stem (hbNES) cells can be derived and massively expanded from early human embryos (week 5-7, C

37 We describe here the structure of a unique, massively expanded state of equine rhinitis A virus that

38 owing that both species have established and massively expanded their range.

39 SNP data from unrelated individuals, termed massively expedited genome-wide heritability analysis (M

40 cage-like iron storage proteins, but with a massively greater capacity (~30,000 iron atoms versus ~3

41 of Sr(2+) at the fast and slow sensors, the massively higher amplitudes of spatially averaged Sr(2+)

42 e, the recovery of the exocrine pancreas was massively impaired in Postn-deficient mice.

43 lal(-/-)) mouse model, melanoma metastasized massively in allogeneic lal(-/-) mice, which was suppres

44 Receptor-like kinases expanded massively in land plants, and leucine-rich repeat recept

45 Ultimately, the goal is to massively increase opportunities for people with MNS dis

46 of lower sea-level and extensive ice-sheets, massively increased seasonal sea-ice coverage and southe

47 activation of a Wnt target gene program that massively increases proliferation and leads to malignant

48 We show that moderate intrinsic noise massively increases the range of synaptic strengths supp

49 t much of it took place comparatively early, massively independently, and with lineage-specific rates

50 ence, PTEN null prostate tumours in mice are massively infiltrated by a population of CD11b(+)Gr-1(+)

51 Lungs of infected mice were massively infiltrated by aggregates of activated platele

52 (CD) and ulcerative colitis (UC), the gut is massively infiltrated with B cells and plasma cells, but

53 The mammalian visual cortex massively innervates the brainstem, a phylogenetically o

54 ow, in this framework, humans can be able to massively interact and to build shared worlds that are b

55 ymorphonuclear neutrophils (PMNs), recruited massively into the CF airway lumen and actively exocytos

56 These blood vessels were massively invaded by bacteria, which adhered to and form

57 be produced at a frenetic pace, resulting in massively large catalogs of human genomic variation.

58 of inferences that can be made from existing massively large exome-sequencing datasets.

59 A continuing challenge in the analysis of massively large sequencing data sets is quantifying and

60 st several decades, the continuing deluge of massively large sequencing data sets presents new opport

61 ows us to introduce a scalable algorithm for massively large-scale networks.

62 libraries and reading the barcodes out using massively multiplexed fluorescence in situ hybridization

63 Here, we present a massively multiplexed yeast two-hybrid method, CrY2H-seq

64 pressed than in females and iron accumulates massively not only in the liver but also in the pancreas

65 twork development in the brain, synapses are massively over-produced and then pruned-back over time.

66 A universal, computationally efficient and massively parallel 3D Monte Carlo code, IM3D, has been d

67 oughput sequencing-based methodology for the massively parallel analysis of transcription from a high

68 dual tracer injections into HVC) to reveal a massively parallel and in some cases topographic pattern

69 We describe a massively parallel approach for designing, manufacturing

70 A new study uses a massively parallel approach, deep mutational scanning, t

71 This work shows how massively parallel approaches can improve the functional

72 is work forms the foundation for a scalable, massively parallel architecture of 1d nanoelectronic dev

73 d methods, quantitative analysis of RNA on a massively parallel array (RNA-MaP) and RNA Bind-n-Seq (R

74 ggest that quantitative analysis of RNA on a massively parallel array (RNA-MaP) provides generalizabl

75 6-well analytical approach will facilitate a massively parallel assessment of the PDC interfacial int

76 e we use microfluidic chemical gradients and massively parallel automated tracking to study the behav

77 To enable massively parallel characterization of genetic combinati

78 s, and phenotypes, where it could accelerate massively parallel combinatorial genetics studies for a

79 processing unit processor markets, enabling massively parallel computations that are not yet fully e

80 otocols (with freeware) capable of accurate, massively parallel de novo assembly of high quality DNA

81 e of supporting plasmid replication and uses massively parallel deep mutational scanning to define mo

82 Our platform enables massively parallel detection of genetic elements, includ

83 nergy harvesting and scavenging displays and massively parallel display-to-display data communication

84 hod that couples ligand-affinity capture and massively parallel DNA sequencing (Chem-seq) to identify

85 Chromatin immunoprecipitation with massively parallel DNA sequencing (ChIP-seq) has greatly

86 ssessed by chromatin immunoprecipitation and massively parallel DNA sequencing (ChIP-seq).

87 e combined in vitro nucleobase excision with massively parallel DNA sequencing (Excision-seq) to dete

88 ing of probe signals for optimal analysis by massively parallel DNA sequencing (RASL-seq).

89 ied in 40 chromatin immunoprecipitation with massively parallel DNA sequencing experiments.

90 Massively parallel DNA sequencing generates staggering a

91 Massively parallel DNA sequencing has shown that de-novo

92 We performed targeted capture and massively parallel DNA sequencing of 619 cancer genes to

93 ral antibodies using immunoprecipitation and massively parallel DNA sequencing of a bacteriophage lib

94 as significantly mutated through large-scale massively parallel DNA sequencing of chronic lymphocytic

95 Chromatin immunoprecipitation followed by massively parallel DNA sequencing showed that genes invo

96 Chromatin immunoprecipitation combined with massively parallel DNA sequencing was performed to chara

97 d by 5'-to-3' exonuclease treatment and then massively parallel DNA sequencing) to GATA1 and TAL1 to

98 and Chem-seq (chemical affinity capture and massively parallel DNA sequencing), are enabling the com

99 q (chromatin immunoprecipitation followed by massively parallel DNA sequencing).

100 In contrast with advances in massively parallel DNA sequencing, high-throughput prote

101 by chromatin immunoprecipitation coupled to massively parallel DNA sequencing, we identified the miR

102 eps for library construction and analysis by massively parallel DNA sequencing.

103 ty enrichment is subjected to analysis using massively parallel DNA sequencing.

104 irements for ISFET pH detection, and enables massively parallel droplet interrogation for application

105 ection strategy represents a step toward the massively parallel electrical monitoring, identification

106 This massively parallel enzyme kinetics analysis detailed the

107 port for convergent evolutionary origins and massively parallel evolution of the entire transcriptome

108 Here, we use massively parallel exome and targeted level sequencing o

109 Here, we describe the results of massively parallel exome sequencing and single nucleotid

110 derlying genetics, we analyzed 48 SI-NETs by massively parallel exome sequencing.

111 Here we describe a massively parallel experiment to systematically test the

112 We describe a massively parallel experimental approach to quantify how

113 aturing field of silicon photonics, enabling massively parallel fabrication of photonic structures.

114 rocess can be performed on a single GPU in a massively parallel fashion.

115 generate sub-100-nm molecular features in a massively parallel fashion.

116 Our approach should enable massively parallel functional analysis of a wide range o

117 We developed a method for massively parallel functional annotation of sequences fr

118 Sequencing-based, massively parallel genetic assays have revolutionized ou

119 led characterization of metagenomics through massively parallel genomic DNA sequencing.

120 ls in human pain disorders, and targeted and massively parallel genomic sequencing is beginning to be

121 ndom 5' UTRs and assayed their activity in a massively parallel growth selection experiment.

122 In this review, we describe several massively parallel high-throughput DNA sequencing techno

123 Massively parallel high-throughput sequencing technology

124 t study describes extremely high-throughput, massively parallel in silico ligand docking studies aime

125 The brain is capable of massively parallel information processing while consumin

126 whole-transcriptome or genomic analysis in a massively parallel manner with minimal reagent use.

127 We then carried out massively parallel mate-pair next generation sequencing

128 Using a massively parallel method to quantify protein-DNA intera

129 ared to that of the parental strain Asibi by massively parallel methods.

130 arise due to somatic mutation and performed massively parallel mRNA sequencing on affected tissue fr

131 The advent of massively parallel next-generation sequencing facilitate

132 CRISPR-Cas9 gene editing in combination with massively parallel oligomer synthesis can enable trackab

133 This protocol provides a massively parallel pipeline to achieve high stringency a

134 Expansion of these approaches into massively parallel platforms establishes the ability to

135 nefit from the computational capabilities of massively parallel processors.

136 A-sequencing (dscRNA-seq) has enabled rapid, massively parallel profiling of transcriptomes.

137 ence electrode that limits the potential for massively parallel reaction detection.

138 veloped and applied a novel lentivirus-based massively parallel reporter assay (lentiMPRA) to directl

139 To address this challenge, we adapted the massively parallel reporter assay (MPRA) to identify var

140 Here, we use a massively parallel reporter assay (MPRA) to measure the

141 We employ a massively parallel reporter assay (MPRA) to simultaneous

142 matic interrogation of the HLA-G locus using massively parallel reporter assay (MPRA) uncovered a pre

143 Using chromatin interaction sequencing, massively parallel reporter assays (MPRA), and transgeni

144 hroughput reporter assay experiments such as massively parallel reporter assays (MPRAs) and similar m

145 y from p53-bound sequences using a series of massively parallel reporter assays (MPRAs) coupled with

146 Massively parallel reporter assays (MPRAs) enable nucleo

147 To address this issue, massively parallel reporter assays (MPRAs) have emerged,

148 Here, we used massively parallel reporter assays (MPRAs) involving 32,

149 Here we introduce UTR-seq, a combination of massively parallel reporter assays and regression models

150 and the inferred specificity of TRUB1 using massively parallel reporter assays in which we monitored

151 on blood lipid-associated loci, we performed massively parallel reporter assays to screen candidate f

152 We perform targeted massively parallel resequencing of 19 known and 46 candi

153 Massively parallel RNA sequencing (RNA-seq) has rapidly

154 We performed massively parallel RNA sequencing in GCs and matched nor

155 Here, we created a platform for the massively parallel screening of barcoded combinatorial g

156 on chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-Seq) methods that pr

157 ed chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq), 1 d after 7 da

158 ctivating histone modifications coupled with massively parallel sequencing (ChIP-seq).

159 ies, 2) DNaseI hypersensitivity coupled with massively parallel sequencing (DNase-seq), and 3) chroma

160 ad mutation(s) in the same gene but targeted massively parallel sequencing (MPS) of 1,034 genes encod

161 Massively parallel sequencing (MPS) technologies includi

162 We used degenerate PCR assays and massively parallel sequencing (MPS) to identify a novel

163 Massively parallel sequencing (MPS) was performed with 2

164 for the presence of somatic mutations using massively parallel sequencing (next-generation sequencin

165 Purpose Massively parallel sequencing allows simultaneous testin

166 high throughput molecular techniques such as massively parallel sequencing and phylogenetic microarra

167 Already, the combination of massively parallel sequencing and selective capture appr

168 juvenile crabs and oysters from the UK using massively parallel sequencing and targeted primer approa

169 tion are identified in single RNA strands by massively parallel sequencing and then analyzed for corr

170 (351) of infant and young SD decedents using massively parallel sequencing at <$600 per sample.

171 isplays clonal DNA methylation patterns from massively parallel sequencing data aligned using Bismark

172 Finding somatic mutations from massively parallel sequencing data is becoming a standar

173 ame feasible with the recent availability of massively parallel sequencing for detection of all codin

174 ns of individual genomic cleavage events via massively parallel sequencing has enabled in vivo DNase

175 Recently, massively parallel sequencing has identified recurrent m

176 Massively parallel sequencing has not previously been le

177 Massively parallel sequencing has permitted an unprecede

178 Massively parallel sequencing has proven revolutionary,

179 l strategies including the new technology of massively parallel sequencing has provided insight into

180 Massively parallel sequencing has revealed many de novo

181 Short-read massively parallel sequencing has revolutionized our abi

182 quences by chromatin immunoprecipitation and massively parallel sequencing identified 2294 peaks.

183 We performed massively parallel sequencing in a blinded fashion to de

184 Clinical samples were sequenced on a massively parallel sequencing instrument, and anaplastic

185 olecular barcoding and can be applied to any massively parallel sequencing instrument.

186 Massively parallel sequencing is increasingly used to in

187 Massively parallel sequencing is performed on libraries

188 stinct populations sequenced with orthogonal massively parallel sequencing methods.

189 Genomic analysis by massively parallel sequencing of 504 cancer genes was pe

190 We employed massively parallel sequencing of all X-chromosome exons

191 methylation results from targeted amplicon, massively parallel sequencing of bisulfite converted DNA

192 Massively parallel sequencing of CSF ctDNA more comprehe

193 rty-nine CMT genes were analyzed by targeted massively parallel sequencing of genomic DNA from patien

194 The use of massively parallel sequencing of maternal cfDNA for non-

195 noninvasive prenatal testing with the use of massively parallel sequencing of maternal plasma cell-fr

196 We performed massively parallel sequencing of paired tumor/normal sam

197 Recently, methods for massively parallel sequencing of ribosome-bound fragment

198 homozygosity mapping, Sanger sequencing, and massively parallel sequencing of the whole exome.

199 ric CN-AML, we performed whole-transcriptome massively parallel sequencing on blasts from 7 CN-AML pe

200 Studying tumor SCNAs using massively parallel sequencing provides unprecedented res

201 Massively parallel sequencing studies have led to the id

202 In this study, a massively parallel sequencing technique that is based on

203 Massively parallel sequencing technologies are useful fo

204 ver the past decade, the decreasing costs of massively parallel sequencing technologies have facilita

205 Recent studies using massively parallel sequencing technologies have implicat

206 In recent years, advances in massively parallel sequencing technologies have led to r

207 Massively parallel sequencing technologies provide great

208 enomics has grown rapidly with the advent of massively parallel sequencing technologies, allowing for

209 With the wide availability of massively parallel sequencing technologies, genetic mapp

210 he advent and application of next-generation massively parallel sequencing technologies, one can rapi

211 hment), a method for aptamer discovery, with massively parallel sequencing technologies.

212 being discovered at an increasing rate using massively parallel sequencing technologies.

213 Massively parallel sequencing technology coupled with sa

214 Massively parallel sequencing technology has made signif

215 The emergence of massively parallel sequencing technology has revolutioni

216 orm whole-exome analyses of 22 tumours using massively parallel sequencing to determine the mutationa

217 We used massively parallel sequencing to examine tumor samples c

218 Massively parallel sequencing to identify rare variants

219 sociated with chemotherapy exposure, we used massively parallel sequencing to quantitate mutations in

220 the past 15 years, technology, particularly massively parallel sequencing, and bioinformatics advanc

221 cancers using gene copy number profiling and massively parallel sequencing, and identified potential

222 mented includes targeted genomic enrichment, massively parallel sequencing, bioinformatic analysis, a

223 With the advent of massively parallel sequencing, considerable work has gon

224 With the emergence of massively parallel sequencing, genomewide expression dat

225 Novel methods, such as massively parallel sequencing, have begun to describe th

226 or the inclusion of somatic mutation data by massively parallel sequencing, we propose a framework fo

227 d challenges arising from the application of massively parallel sequencing-also known as next-generat

228 RNA editing and global gene expression using massively parallel sequencing.

229 gestion of nuclei withMPE-Fe(II) followed by massively parallel sequencing.

230 and then counting the resulting mutations by massively parallel sequencing.

231 rming growth factor beta 1 (TGFbeta1), using massively parallel sequencing.

232 blockade were characterized with the use of massively parallel sequencing.

233 otides during cDNA synthesis, as measured by massively parallel sequencing.

234 say (OLA), an economical and simple test, to massively parallel sequencing.

235 ols were pooled respectively and profiled by massively parallel sequencing.

236 abled a complex mutant pool to be tracked by massively parallel sequencing.

237 c aHUS using targeted genomic enrichment and massively parallel sequencing.

238 e sensitivity of detecting such mutations by massively parallel sequencing.

239 ormed using the large-scale Atomic/Molecular Massively Parallel Simulator (LAMMPS) with a reactive fo

240 Massively parallel single-cell droplet polymerase chain

241 To address these challenges, we used massively parallel single-cell RNA profiling and optimiz

242 Recent advances such as massively parallel single-cell RNA sequencing and sophis

243 Massively parallel single-cell RNA sequencing can precis

244 Seq-Well, a portable, low-cost platform for massively parallel single-cell RNA-seq.

245 n of a systematic allelic series (SAS) using massively parallel single-nucleotide mutagenesis with re

246 Here, we develop DroNc-seq: massively parallel sNuc-seq with droplet technology.

247 s an effective and efficient tool to analyze massively parallel spike data for temporal sequences of

248 oduced a method for visualization of SSEs in massively parallel spike trains, based on an intersectio

249 hed disease-causing exonic mutations using a massively parallel splicing assay (MaPSy), which showed

250 Massively parallel strand-specific sequencing of RNA (ss

251 ap in the pipeline for automated analysis of massively parallel targeted proteomics data sets.

252 Massively parallel trapping of more than 100,000 micropa

253 In this study, advanced massively parallel WGS was performed on three 5- to 10-c

254 enetic alterations that underpin SPCRP using massively parallel whole-exome and targeted sequencing.

255 Massively parallel whole-genome sequencing (WGS) data ha

256 Massively parallel, high-throughput sequencing technolog

257 Here, we report a massively parallel, multigene-profiling nanoplatform to

258 The advent of massively parallel, next-generation sequencing promises

259 STR-selective primers enable massively parallel, targeted sequencing of large STR set

260 ensing interfaces and as the transducer in a massively parallel, wide field, single molecule detectio

261 The sensitivity of massively-parallel sequencing has confirmed that most ca

262 tify promising detection strategies based on massively-parallel sequencing.

263 novative microfluidic technology has enabled massively parallelized and extremely efficient biologica

264 However, an alternative massively parallelized configuration, capable of interro

265 In the last years, applications based on massively parallelized RNA sequencing (RNA-seq) have bec

266 of a membrane-less microfiltration system by massively parallelizing inertial microfluidics to achiev

267 The availability of deep coverage data from massively parallizable sequencing technologies means tha

268 lar input patterns in the olfactory bulb are massively perturbed and olfactory behaviors are altered.

269 asmacytoid dendritic cells (pDC) rapidly and massively produce type I IFN and other inflammatory cyto

270 The massively produced (1)O2 can compromise the integrity of

271 DCS cells can be massively produced from Lgr5(+) colon stem cells in vitr

272 f human innate and adaptive immunity and are massively produced from plasmacytoid dendritic cells (pD

273 ch syndrome protein Homology 2 (WH2) domain, massively promoted the formation of F-actin-rich membran

274 nd that approximately 4% of the samples have massively rearranged chromosomes, many of which are asso

275 Mycobacterium tuberculosis, neutrophils are massively recruited to the lungs, but the role of these

276 g neural networks are sufficiently noisy and massively redundant.

277 artner defense system is activated and olive massively releases the arsenal of defense.

278 d cells) becomes highly up-regulated and can massively reorganize the bacterial chromosome.

279 hromatin accessibility revealed that fasting massively reorganizes liver chromatin, exposing numerous

280 ng RNA-genome interactions), a technology to massively reveal native RNA-chromatin interactions from

281 pping RNA interactome in vivo) technology to massively reveal RNA-RNA interactions from unperturbed c

282 human pathogen that, under KdgR regulation, massively secrete enzymes such as pectinases that degrad

283 s, whereas the ORF2g and ORF2c proteins were massively secreted glycoproteins not associated with inf

284 lecular markers, and their use has increased massively since the inception of Next Generation Sequenc

285 Coleoptera (beetles) is a massively successful order of insects, distinguished by

286 is of transcript ends and transcript yields (massively systematic transcript end readout, "MASTER").

287 First, using massively systematic transcript end readout, MASTER, we

288 infection when host populations are expanded massively through fungiculture.

289 ts phenotypically resembling PKD that expand massively to 1-centimetre diameters.

290 ird of photosynthetic flux, thus contributes massively to the global carbon cycle.

291 Exploratory subgroups included massively transfused and severe TBI patients.

292 inistration of blood component ratios in the massively transfused nontrauma demographic.

293 Among 601 massively transfused nontrauma patients, cardiothoracic

294 Massively transfused nontrauma patients.

295 paucity of comprehensive descriptions of the massively transfused patients and their outcomes.

296 Also, 50% of massively transfused patients in hemorrhagic shock demon

297 atient characteristics, and the mortality of massively transfused patients.

298 ot observed in this analysis of a nontrauma, massively transfused population.

299 73.5% blunt mechanism, 47% severe TBI, 20.5% massively transfused.

300 s rapidly remodeled while active cofilin was massively transported to the spine.