ライフサイエンスコーパス: massively-parallel sequencing

1 n, let alone more complex, disorders through massively parallel sequencing.

2 ghput commensurate with the current scale of massively parallel sequencing.

3 is modified with unique flanking tags before massively parallel sequencing.

4 that have become feasible with the advent of massively parallel sequencing.

5 ary using affinity purification coupled with massively parallel sequencing.

6 latforms have been developed with the use of massively parallel sequencing.

7 iopathy candidate exome capture' followed by massively parallel sequencing.

8 cted the exomes of ten unrelated probands to massively parallel sequencing.

9 five-microorganism metatranscriptomes using massively parallel sequencing.

10 es by coupling proximity-based ligation with massively parallel sequencing.

11 re required to realize the full potential of massively parallel sequencing.

12 extended the TimEX method genome-wide using massively parallel sequencing.

13 hIP-seq) data obtained by coupling ChIP with massively parallel sequencing.

14 RNA editing and global gene expression using massively parallel sequencing.

15 gestion of nuclei withMPE-Fe(II) followed by massively parallel sequencing.

16 and then counting the resulting mutations by massively parallel sequencing.

17 rming growth factor beta 1 (TGFbeta1), using massively parallel sequencing.

18 blockade were characterized with the use of massively parallel sequencing.

19 otides during cDNA synthesis, as measured by massively parallel sequencing.

20 say (OLA), an economical and simple test, to massively parallel sequencing.

21 ols were pooled respectively and profiled by massively parallel sequencing.

22 e sensitivity of detecting such mutations by massively parallel sequencing.

23 abled a complex mutant pool to be tracked by massively parallel sequencing.

24 c aHUS using targeted genomic enrichment and massively parallel sequencing.

25 es of specific genomic loci (40 cases) using massively parallel sequencing.

26 short hairpin RNA (shRNA) library screen and massively parallel sequencing.

27 tify promising detection strategies based on massively-parallel sequencing.

28 Using a GWAS approach and target-enriched massively-parallel sequencing, a strongly associated non

29 Purpose Massively parallel sequencing allows simultaneous testin

30 In contrast, massively parallel sequencing allows such testing for ma

31 d challenges arising from the application of massively parallel sequencing-also known as next-generat

32 ls, and by chromatin immunoprecipitation and massively parallel sequencing analysis of gammaH2AX, we

33 ve chromatin immunoprecipitation followed by massively parallel sequencing analysis of H3K9me2 distri

34 f neoadjuvant aromatase inhibitor therapy by massively parallel sequencing and analysis.

35 map temporally ordered replicating DNA using massively parallel sequencing and applied it to study re

36 We undertook sequence capture, massively parallel sequencing and computational alignmen

37 of chromatin immunoprecipitation coupled to massively parallel sequencing and gene expression data.

38 ring high performance liquid chromatography, massively parallel sequencing and multiplex-ligation-dep

39 high throughput molecular techniques such as massively parallel sequencing and phylogenetic microarra

40 Massively parallel sequencing and related methods reveal

41 Already, the combination of massively parallel sequencing and selective capture appr

42 Massively parallel sequencing and splicing-sensitive jun

43 juvenile crabs and oysters from the UK using massively parallel sequencing and targeted primer approa

44 tion are identified in single RNA strands by massively parallel sequencing and then analyzed for corr

45 the past 15 years, technology, particularly massively parallel sequencing, and bioinformatics advanc

46 cancers using gene copy number profiling and massively parallel sequencing, and identified potential

47 enhancer-associated protein p300 followed by massively parallel sequencing, and map several thousand

48 sm mapping, microsatellite linkage, targeted massively parallel sequencing, and Sanger sequencing.

49 roductive and latent infection, we applied a massively parallel sequencing approach.

50 factor in the vastly improved efficiency of massively parallel sequencing approaches.

51 Technologies for massively parallel sequencing are revolutionizing microb

52 generates products suitable for analysis by massively parallel sequencing as well as microarray hybr

53 (351) of infant and young SD decedents using massively parallel sequencing at <$600 per sample.

54 mented includes targeted genomic enrichment, massively parallel sequencing, bioinformatic analysis, a

55 Massively parallel sequencing by oligonucleotide ligatio

56 Using massively parallel sequencing by synthesis methods, we h

57 sequencing of mtDNA genomes with the use of massively parallel sequencing-by-synthesis approaches.

58 A massively parallel sequencing-by-synthesis method (454 s

59 e used on as little as 10 ng of DNA and that massively parallel sequencing can be used as an alternat

60 Here, we used ChIP coupled to massively parallel sequencing (ChIP-seq) and gene expres

61 Chromatin immunoprecipitation with massively parallel sequencing (ChIP-seq) coupled to time

62 y chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-Seq) has recently be

63 ChIP followed by massively parallel sequencing (ChIP-Seq) is a powerful,

64 on chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-Seq) methods that pr

65 m chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-seq) of multiple tra

66 , we used chromatin immunoprecipitation with massively parallel sequencing (ChIP-seq) on CRX to ident

67 chromatin immunoprecipitation combined with massively parallel sequencing (ChIP-seq) to identify >75

68 e chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-Seq) to identify bet

69 ly, chromatin immunoprecipitation coupled to massively parallel sequencing (ChIP-seq) to identify gen

70 , we used chromatin immunoprecipitation with massively parallel sequencing (ChIP-seq) to identify Hox

71 ed chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq), 1 d after 7 da

72 ng chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq), 312 chromosoma

73 matin immunoprecipitation (ChIP) paired with massively parallel sequencing (ChIP-seq), gene expressio

74 tin immunoprecipitation (ChIP) combined with massively parallel sequencing (ChIP-Seq), we show that F

75 by chromatin immunoprecipitation coupled to massively parallel sequencing (ChIP-seq).

76 ir-end tag sequencing (ChIP-PET), to current massively parallel sequencing (ChIP-seq).

77 ctivating histone modifications coupled with massively parallel sequencing (ChIP-seq).

78 Whole-exome capture and massively parallel sequencing combined with homozygosity

79 With the advent of massively parallel sequencing, considerable work has gon

80 Recently, massively parallel sequencing coupled with ChIP experime

81 isplays clonal DNA methylation patterns from massively parallel sequencing data aligned using Bismark

82 gene expression, chromosomal copy number and massively parallel sequencing data from 947 human cancer

83 Finding somatic mutations from massively parallel sequencing data is becoming a standar

84 on in sequence markedly under-represented in massively parallel sequencing data: the insertion of a s

85 DNaseI digestion of chromatin coupled with massively parallel sequencing (digital genomic footprint

86 ies, 2) DNaseI hypersensitivity coupled with massively parallel sequencing (DNase-seq), and 3) chroma

87 xplores the current state of genomics in the massively parallel sequencing era.

88 Massively parallel sequencing facilitates strain-to-refe

89 Four studies have shown the utility of massively parallel sequencing for comprehensive genetic

90 ame feasible with the recent availability of massively parallel sequencing for detection of all codin

91 Our results reveal the value of massively parallel sequencing for identification of nove

92 ng chromatin immunoprecipitation followed by massively parallel sequencing, genome-wide maps of candi

93 With the emergence of massively parallel sequencing, genomewide expression dat

94 ns of individual genomic cleavage events via massively parallel sequencing has enabled in vivo DNase

95 Using massively parallel sequencing has enabled investigators

96 Massively parallel sequencing has enabled the rapid, sys

97 Recently, massively parallel sequencing has identified recurrent m

98 Massively parallel sequencing has not previously been le

99 Massively parallel sequencing has permitted an unprecede

100 Massively parallel sequencing has proven revolutionary,

101 l strategies including the new technology of massively parallel sequencing has provided insight into

102 Massively parallel sequencing has revealed many de novo

103 Short-read massively parallel sequencing has revolutionized our abi

104 The sensitivity of massively-parallel sequencing has confirmed that most ca

105 Novel methods, such as massively parallel sequencing, have begun to describe th

106 Massively parallel sequencing identified 12,732-19,704 H

107 quences by chromatin immunoprecipitation and massively parallel sequencing identified 2294 peaks.

108 We performed massively parallel sequencing in a blinded fashion to de

109 brain development and emphasize the power of massively parallel sequencing in a challenging context o

110 with solution-based whole-exome capture and massively parallel sequencing in a large Caucasian pedig

111 Anti-Brd3 ChIP followed by massively parallel sequencing in GATA1-deficient erythro

112 d to 7.4-fold redundancy in two months using massively parallel sequencing in picolitre-size reaction

113 of KERV long terminal repeat sequences using massively parallel sequencing indicates that the recent

114 Clinical samples were sequenced on a massively parallel sequencing instrument, and anaplastic

115 olecular barcoding and can be applied to any massively parallel sequencing instrument.

116 Although massively parallel sequencing instruments are in princip

117 Massively parallel sequencing instruments enable rapid a

118 an substantially increase the sensitivity of massively parallel sequencing instruments for this purpo

119 Massively parallel sequencing is increasingly used to in

120 Massively parallel sequencing is performed on libraries

121 We conclude that massively parallel sequencing is useful to characterize

122 cipitation (ChIP) with ultra high-throughput massively parallel sequencing, is increasingly being use

123 es chromatin immunoprecipitation (ChIP) with massively parallel sequencing, is rapidly replacing ChIP

124 cost and throughput advances associated with massively parallel sequencing, it remains challenging to

125 nces in sequencing technologies suggest that massively parallel sequencing may provide a feasible alt

126 rotein 2 (MBD) enrichment of DNA followed by massively parallel sequencing (MBD-seq) was used to map

127 In this study, we used exon capture and massively parallel sequencing methods to analyze the mut

128 Using massively parallel sequencing methods, we have identifie

129 stinct populations sequenced with orthogonal massively parallel sequencing methods.

130 New 'massively parallel' sequencing methods are greatly incre

131 Here we propose to use massively parallel sequencing (MPS) for sensitive detect

132 ad mutation(s) in the same gene but targeted massively parallel sequencing (MPS) of 1,034 genes encod

133 We used massively parallel sequencing (MPS) of the 16S rRNA gene

134 Massively parallel sequencing (MPS) technologies includi

135 We used degenerate PCR assays and massively parallel sequencing (MPS) to identify a novel

136 Massively parallel sequencing (MPS) was performed with 2

137 alysis and interpretation of assays based on massively-parallel sequencing (MPS) are both individuall

138 for the presence of somatic mutations using massively parallel sequencing (next-generation sequencin

139 a proof of principle, we performed targeted, massively parallel sequencing of 138 cancer genes in a t

140 Here we report the massively parallel sequencing of 38 tumour genomes and t

141 Genomic analysis by massively parallel sequencing of 504 cancer genes was pe

142 h chronic lymphocytic leukemia and performed massively parallel sequencing of 88 whole exomes and who

143 capillary sequencing of candidate genes, and massively parallel sequencing of all coding exons.

144 We employed massively parallel sequencing of all X-chromosome exons

145 methylation results from targeted amplicon, massively parallel sequencing of bisulfite converted DNA

146 Massively parallel sequencing of captured subgenomic lib

147 Using paired-end massively parallel sequencing of cDNA (RNA-seq) together

148 Massively parallel sequencing of cDNA has enabled deep a

149 ons in solid cancers can be characterized by massively parallel sequencing of circulating cell-free t

150 Massively parallel sequencing of CSF ctDNA more comprehe

151 Massively parallel sequencing of DNA by pyrosequencing t

152 rty-nine CMT genes were analyzed by targeted massively parallel sequencing of genomic DNA from patien

153 characterized MdBV replication and performed massively parallel sequencing of M. demolitor ovary tran

154 The use of massively parallel sequencing of maternal cfDNA for non-

155 noninvasive prenatal testing with the use of massively parallel sequencing of maternal plasma cell-fr

156 Massively parallel sequencing of millions of < 30-nt RNA

157 oning analysis of Arabidopsis thaliana using massively parallel sequencing of mononucleosomes.

158 We performed massively parallel sequencing of paired tumor/normal sam

159 Herein, massively parallel sequencing of Podophyllum hexandrum a

160 l relevance of MEK dependency in melanoma by massively parallel sequencing of resistant clones genera

161 Recently, methods for massively parallel sequencing of ribosome-bound fragment

162 Massively parallel sequencing of Sin3A- and Sin3B-bound

163 Massively parallel sequencing of targeted regions, exome

164 Massively parallel sequencing of the entire 2.2-Mb inter

165 Here we report on the targeted capture and massively parallel sequencing of the exomes of 12 humans

166 with reduced genomic library preparation and massively parallel sequencing of the same samples using

167 homozygosity mapping, Sanger sequencing, and massively parallel sequencing of the whole exome.

168 Massively parallel sequencing of this representation all

169 ines high-density transposon mutagenesis and massively parallel sequencing of transposon/chromosome j

170 disorders can be rapidly discovered through massively parallel sequencing of whole genomes or exomes

171 e, confirm linkage to Xp11.23-q13.3, perform massively parallel sequencing of X chromosome exons, fil

172 ric CN-AML, we performed whole-transcriptome massively parallel sequencing on blasts from 7 CN-AML pe

173 ing on the flow cells of currently available massively parallel sequencing platforms as an efficient

174 Recent progress in massively parallel sequencing platforms has enabled geno

175 Studying tumor SCNAs using massively parallel sequencing provides unprecedented res

176 rization of sequencing chemistries, enabling massively parallel sequencing reactions to be carried ou

177 Targeting genomic loci by massively parallel sequencing requires new methods to en

178 Massively parallel sequencing studies have led to the id

179 In this study, a massively parallel sequencing technique that is based on

180 The development of massively parallel sequencing techniques has presented t

181 Massively parallel sequencing technologies are useful fo

182 We show that new high-throughput, massively parallel sequencing technologies can completel

183 Massively parallel sequencing technologies can overcome

184 The advent of massively parallel sequencing technologies has allowed t

185 precipitation (ChIP) with recently developed massively parallel sequencing technologies has enabled g

186 cost due to the emergence and improvement of massively parallel sequencing technologies has resulted

187 ver the past decade, the decreasing costs of massively parallel sequencing technologies have facilita

188 Recent studies using massively parallel sequencing technologies have implicat

189 In recent years, advances in massively parallel sequencing technologies have led to r

190 Massively parallel sequencing technologies have made the

191 The massively parallel sequencing technologies have recently

192 Massively parallel sequencing technologies hold incredib

193 ly from personal genomes sequenced using the massively parallel sequencing technologies is becoming a

194 Massively parallel sequencing technologies provide great

195 Massively parallel sequencing technologies provide sensi

196 ess the feasibility of target-enrichment and massively parallel sequencing technologies to interrogat

197 enomics has grown rapidly with the advent of massively parallel sequencing technologies, allowing for

198 The development of massively parallel sequencing technologies, coupled with

199 With the wide availability of massively parallel sequencing technologies, genetic mapp

200 he advent and application of next-generation massively parallel sequencing technologies, one can rapi

201 ness, both of which have been enabled by new massively parallel sequencing technologies.

202 hment), a method for aptamer discovery, with massively parallel sequencing technologies.

203 being discovered at an increasing rate using massively parallel sequencing technologies.

204 quencing is performed with 'next-generation' massively parallel sequencing technologies: in June 2008

205 Massively parallel sequencing technology and the associa

206 The massively parallel sequencing technology can be used by

207 Massively parallel sequencing technology coupled with sa

208 New massively parallel sequencing technology enables, throug

209 Massively parallel sequencing technology has made signif

210 The emergence of massively parallel sequencing technology has revolutioni

211 Recent advances in massively parallel sequencing technology have created ne

212 seq (chromatin immunoprecipitation following massively parallel sequencing technology).

213 Using massively parallel sequencing technology, we sequenced a

214 d it would be highly desirable to apply such massively parallel sequencing to bisulfite-converted who

215 erial small-subunit (16S) rRNA combined with massively parallel sequencing to determine the community

216 ed a targeted captured technique followed by massively parallel sequencing to determine the exact bre

217 orm whole-exome analyses of 22 tumours using massively parallel sequencing to determine the mutationa

218 ntly, a genome-wide study was reported using massively parallel sequencing to directly compare in viv

219 We used massively parallel sequencing to examine tumor samples c

220 Here, we used massively parallel sequencing to explore samples from a

221 In this study, we used Illumina-based massively parallel sequencing to gain new insight into t

222 We used massively parallel sequencing to generate sequence reads

223 We performed massively parallel sequencing to identify gastrointestin

224 Massively parallel sequencing to identify rare variants

225 Here, we have used genome-wide massively parallel sequencing to map replication initiat

226 a library of barcoded lentiviruses and used massively parallel sequencing to quantify the clonal dis

227 sociated with chemotherapy exposure, we used massively parallel sequencing to quantitate mutations in

228 We used exome capture coupled with massively parallel sequencing to search for metastasis-r

229 Therefore, we employed massively parallel sequencing to search for somatic mosa

230 ChIP-seq (chromatin immunoprecipitation with massively parallel sequencing) to analyze the genome-wid

231 dologies (multiplex target amplification and massively parallel sequencing) to historical specimens f

232 itro DNA affinity purification combined with massively parallel sequencing, to identify B. subtilis c

233 Here, using massively parallel sequencing, we characterize expressed

234 immunoprecipitation experiments coupled with massively parallel sequencing, we found that genome-wide

235 Combining whole-genome shRNA screening with massively parallel sequencing, we have profiled the impa

236 hod that combines end-sequence profiling and massively parallel sequencing, we obtained a sequence-le

237 or the inclusion of somatic mutation data by massively parallel sequencing, we propose a framework fo

238 me can be detected by microarray methods and massively parallel sequencing, which identify copy-numbe

239 Here we combine the throughput of massively parallel sequencing with the contiguity inform