ライフサイエンスコーパス: mast cell line

1 downregulated the growth of the HMC1.2 human mast cell line.

2 reduced the viability of a canine malignant mast cell line.

3 glandin D2 production by LAD2 cells, a human mast cell line.

4 culating progenitors or with the HMC-1 human mast cell line.

5 r in neuronal exocytosis, was expressed in a mast cell line.

6 lated via Kit in a mouse bone marrow-derived mast cell line.

7 no-terminus were expressed in a Syk-negative mast cell line.

8 on in permeabilized RBL-2H3 cells, a mucosal mast cell line.

9 P-1 in rat basophilic leukemia 2H3 (RBL-2H3) mast cell line.

10 s factor alpha (TNF-alpha) by the mouse MC/9 mast cell line.

11 of the RBL-2H3 (rat basophilic leukemia 2H3) mast cell line.

12 urrent (Icrac) was investigated in the RBL-1 mast cell line.

13 FAK cDNA into a variant (3B6) of the RBL-2H3 mast cell line.

14 C, or Syp), are expressed in the RBL-2H3 rat mast cell line.

15 A2 activity, and cytokine production in this mast cell line.

16 sone on these events in a cultured (RBL-2H3) mast cell line.

17 macologic inhibition of KIT in KIT-dependent mast cell lines.

18 se independent apoptosis in human and murine mast cell lines.

19 ly enhance production of cytokines in murine mast cell lines.

20 17-AAG promotes cell death of both HMC mast cell lines.

21 ent on cell activation signals in both T and mast cell lines.

22 bitor EXEL-0862 against 2 subclones of human mast cell line-1 (HMC-1)-HMC-1.1, harboring the juxtamem

23 sites across 121 proteins in the MCP5 mouse mast cell line and 179 modification sites on 117 protein

24 effect of artesunate was examined in RBL-2H3 mast cell line and in mature human cultured mast cells.

25 ll lines and have been identified in a human mast cell line and in situ in human gastrointestinal str

26 shRNA-mediated knockdown of MrgX2 in LAD2 mast cell line and primary CD34(+) cell-derived mast cel

27 on kinase family, was present in the RBL-2H3 mast cell line and was rapidly tyrosine-phosphorylated a

28 d dose-dependent proapoptotic effect in both mast cell lines and caused a significant reduction in ma

29 ntly induced degranulation of the human LAD2 mast-cell line and cord blood-derived human mast cells (

30 We found that LAD2, a human mast cell line, and CD34(+) cell-derived primary mast ce

31 IL-10 and vIL-10 were compared in B cell and mast cell lines, and demonstrated that the inability of

32 ytometry using peripheral blood eosinophils, mast cell lines, and Siglec-8-transduced cells in the pr

33 We have isolated a unique murine mast cell line, B6M, that is phenotypically similar to i

34 r survival and growth of the IC2-mKit(D814Y) mast cell line both in vitro and in vivo.

35 C) and peritoneal mast cells, as well as two mast cell lines (C57 and MCP-5), constitutively expresse

36 of intact and permeabilized RBL-2H3 (mucosal mast cell line) cells.

37 p161 was purified from the mast cell line CFTL-12 by affinity chromatography and su

38 The cloned growth, factor-independent mast cell line Cl.MC/C57.1 was also studied.

39 , we have isolated and characterized primary mast cell lines derived from the upper airways of normal

40 addition, two mutations were found in three mast cell lines derived from two additional dogs.

41 Mast cell lines expressing either wild-type (WT) Kit, a

42 Mouse and canine malignant mast cell lines expressing various Kit mutations, normal

43 Transient transfections of the human mast cell line HMC-1 and the T cell line Jurkat with rep

44 ional MrgX1 and MrgX2 but the immature human mast cell line HMC-1 does not.

45 We previously showed that the human mast cell line HMC-1 expresses A2A and A2B receptors, an

46 Extending this observation to the human mast cell line HMC-1, we show that these mast cells also

47 human basophil cell line KU812 and the human mast cell line HMC-1.

48 h mesenteric windows (ex vivo) and the human mast cell line HMC-1.

49 d in the SCF receptor gain-of-function human mast cell line HMC-1.

50 Treatment with 17-AAG of the mast cell line HMC-1.2, harboring the Asp816Val and Val5

51 PAI-1 was secreted by both a human mast cell line (HMC)-1 and primary cultured human mast c

52 stine, and in several other tissues and in a mast cell line (HMC-1) that also expresses gamma-tryptas

53 To test this hypothesis, a human mast cell line (HMC-1) that normally expresses receptors

54 levels of IL-6 secreted from human leukemic mast cell line (HMC-1).

55 tions of human mast cells, we analyzed human mast cell lines (HMC-1 and LAD2) depleted of RGS13 by sp

56 marrow-cultured human mast cells and a human mast cell line, HMC-1, as demonstrated by intracytoplasm

57 However, an immature human mast cell line, HMC-1, that lacks functional MrgX2 did n

58 We used a human mast cell line, HMC-1, to determine if mast cells can in

59 ng and biological responses, we used a human mast cell-line, HMC-1, that natively expresses both rece

60 esent in eosinophils, basophils, and a human mast cell line (HMC1), whereas MBP2 is only detected in

61 d signaling pathways activated in the murine mast cell line IC2 infected with either wild-type (IC2-m

62 ation of both airway and bone marrow derived mast cell lines in response to inflammatory and hematopo

63 Tumor mast cell lines, in contrast, expressed persistently hig

64 surface receptors on MMC-34 cells, a murine mast cell line, induces the synthesis and secretion of p

65 We demonstrated that the human mast cell line Laboratory of Allergic Diseases 2 (LAD2)

66 We found that a human mast cell line LAD2 and CD34(+) cell-derived primary mas

67 re, HDPs stimulated degranulation in a human mast cell line (LAD2) and in RBL-2H3 cells stably expres

68 To identify such a receptor two human mast cell lines, LAD2 and LUVA, were selected that diffe

69 tudied for their ability to activate a human mast cell line (LUVA) as determined by cysteinyl leukotr

70 ession of kinase-inactive MKK7 in the murine mast cell line MC/9 inhibits c-Jun NH(2)-terminal kinase

71 The murine mast cell line, MC/9, synthesizes and secretes TNF-alpha

72 tured murine mast cells (BMCMC) and a murine mast cell line (MCP-5) employing flow cytometry and thro

73 one marrow-derived cultured mast cells and a mast cell line, MCP-5.

74 se phosphatase genes was screened in a mouse mast cell line, MMC-1.

75 n microvascular endothelial cell line, human mast cell line, mouse cardiac Sca1-positive stromal cell

76 recognizes c-kit endogenously expressed by a mast cell line or hematopoietic progenitor cells, and sp

77 ctivated by antigen cross-linking in a mouse mast cell line passively sensitized with ovalbumin-speci

78 The rat mast cell line RBL-2H3 contains both phospholipase D (PL

79 The secretion process of the mucosal mast cell line RBL-2H3 was imaged using infrared three p

80 the function of InsP4 in Ca2+ influx in the mast cell line RBL-2H3, and we show that InsP4 inhibits

81 lpha subunit was overexpressed in a cultured mast cell line (RBL-2H3) known to contain G alpha z.

82 tigen clustering of Fc epsilon RI on the rat mast-cell line (RBL-2H3) activates a sphingosine kinase

83 Cells of the mucosal mast cell line, RBL-2H3, are normally stimulated to degr

84 eceptor for IgE (FcepsilonRI) on the mucosal mast cell line, RBL-2H3, results in the rapid and persis

85 y receptors for IgE, Fc epsilon RI, on a rat mast cell line, RBL-2H3, stimulated transcription of the

86 receptors on the widely studied rat mucosal mast cell line, RBL-2H3.

87 uman mast cells as well as the rat and human mast cell lines, RBL-2H3 and HMC-1, produce the heparan

88 n that occur after cannabinoid exposure in a mast cell line, RBL2H3.

89 igh affinity IgE receptor (FcepsilonRI) in a mast cell line resulted in activation of the p42 and the

90 Overexpression of Vav in the RBL-2H3 mast cell line resulted in the constitutive tyrosine pho

91 Expression of human SNAP-23 in a rat mast cell line significantly enhanced exocytosis, and th

92 Furthermore, mast cell lines stably expressing MrgX2 responded to LL-

93 A mouse mast cell line that endogenously expresses mouse mast ce

94 Studies were conducted in two rodent mast cell lines that were stimulated with Ag via Fcepsil

95 In the RBL-2H3 mast cell line, the interaction of PKC-delta with Lyn re

96 nd jejunum of the BALB/c mouse, the V3 mouse mast cell line was used to investigate the developmental

97 hereas maintenance of high activity in tumor mast cell lines was not dependent on intracellular signa

98 cells (RBL-2H3 m1), an immortalized mucosal mast cell line, was studied at the single-channel level

99 In two mast cell lines, we observed mRNA and protein expression

100 cord blood-derived mast cells and the HMC-1 mast cell line were exposed to RSV or UV-inactivated RSV

101 IgE-stripped basophils or a mast cell line were used in passive sensitization activa

102 Pulmonary mast cell lines were capable of proliferating in respons

103 The results from the pulmonary mast cell lines were compared with those from bone marro

104 The primary mast cell lines were grown and maintained by incubation

105 Finally, IL-3-independent mastocytomas and mast cell lines were resistant to apoptosis induced by I

106 Using 2 subclones of the HMC1 mast cell line, which both express KIT with an identical

107 ner and decreased cell proliferation in both mast cell lines with higher activity against HMC-1.2 cel