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1 ion is increasingly performed at the time of mastectomy.
2 ant treatment option for patients undergoing mastectomy.
3 reast cancer, many women continue to undergo mastectomy.
4 dely clear margins is common and may lead to mastectomy.
5 with early-stage breast cancer who underwent mastectomy.
6 ubtypes) with breast conservation therapy or mastectomy.
7 ction to decrease breast complications after mastectomy.
8 but 31% of BCT-eligible patients still chose mastectomy.
9 ectomy, breast reconstruction, and bilateral mastectomy.
10 total of 35.5% of the study cohort underwent mastectomy.
11 underwent breast-conserving surgery (BCS) or mastectomy.
12 s and reexcision among patients with partial mastectomy.
13 03-1.29) influenced axillary evaluation with mastectomy.
14 fter surgeons had completed standard partial mastectomy.
15 l after breast conservation therapy (BCT) vs mastectomy.
16 on lumpectomy and 28,267 (37.9%) underwent a mastectomy.
17 breast cancer detected during a prophylactic mastectomy.
18 breast cancer (58.3%) underwent a bilateral mastectomy.
19 clinical course of treatment by conducting a mastectomy.
20 ived it, while 16 patients (32.7%) underwent mastectomy.
21 ims to identify receipt of RT and subsequent mastectomy.
22 onstructive surgery with patients undergoing mastectomy.
23 ogous IR, DR, and SR breast procedures after mastectomy.
24 over time and are now similar to those after mastectomy.
25 th invasive breast cancer undergoing planned mastectomy.
26 s, and 25 cancers discovered at prophylactic mastectomy.
27 herapy decreases the likelihood of LRR after mastectomy.
28 event for breast cancer patients undergoing mastectomy.
29 Contralateral prophylactic mastectomy.
30 mastectomies, and contralateral prophylactic mastectomies.
31 tients (5%) underwent bilateral prophylactic mastectomy; 1,004 chose surveillance with (n = 173) or w
32 s no-MRI (referent) were as follows: initial mastectomy 16.4% versus 8.1% [OR, 2.22 (P < 0.001); adju
33 ) underwent BCS while 9011 (25.3%) underwent mastectomy; 17.7% undergoing BCS and 63.0% undergoing ma
34 Rates of ALND decreased in women undergoing mastectomy (2006, 20.0%; 2012, 10.7%) and BCS (2006, 1.2
35 axillary evaluation increased over time with mastectomy (2006, 56.6%; 2012, 67.4%) and were relativel
36 .87); adjusted OR, 0.95 (P = 0.71)]; overall mastectomy 25.5% versus 18.2% [OR, 1.54 (P < 0.001); adj
37 and less likely to undergo modified radical mastectomy (25% vs 47% of the Pt/PhysD breast cancer pat
38 ata that included 28,176 women who underwent mastectomy (25,141 mastectomy alone and 3,035 IBR) betwe
40 cer (ILC), outcomes were as follows: initial mastectomy 31.1% versus 24.9% [OR, 1.36 (P = 0.056); adj
41 031); adjusted OR, 0.56 (P = 0.09)]; overall mastectomy 43.0% versus 40.2% [OR, 1.12 (P = 0.45); adju
46 uding the cancers discovered at prophylactic mastectomy (95% confidence interval: 69.5%, 82.4%) and 9
47 at more than 24 months, 28 (6.4%) underwent mastectomy (all benign), and 68 (15.6%) had lesion upgra
48 a higher survival rate than those undergoing mastectomy alone (hazard ratio, 1.31; P < .001) or maste
50 ficantly increased odds of IBR compared with mastectomy alone (odds ratio [OR], 1.71; 95% CI, 1.47 to
51 tly farther compared with those who received mastectomy alone (OR, 1.04; 95% CI, 1.02 to 1.05 for eve
52 8,176 women who underwent mastectomy (25,141 mastectomy alone and 3,035 IBR) between April 1, 2002, a
53 rvival rate compared with those treated with mastectomy alone or mastectomy with radiation for early-
54 n therapy was used to treat 70% of patients, mastectomy alone was used to treat 27% of patients, and
55 vival rates of patients who underwent BCT, a mastectomy alone, or a mastectomy with radiation were 97
56 of local therapy, breast-conserving therapy, mastectomy alone, or mastectomy followed by postmastecto
57 invasive ductal carcinoma treated with BCT, mastectomy alone, or mastectomy with radiation during th
63 lumpectomy and radiation and underwent fewer mastectomies and less chemotherapy than patients with ca
65 eceived CPM, while 45.8% received unilateral mastectomy and 22.8% received breast conservation surger
67 iopsy confirmed breast cancer, she underwent mastectomy and axillary node dissection for a left-sided
68 iopsy confirmed breast cancer, she underwent mastectomy and axillary node dissection for a left-sided
70 i-institutional study of patients undergoing mastectomy and breast conserving surgery was performed f
71 s incur potential morbidity, especially when mastectomy and breast reconstruction are done for widesp
73 ve review of all patients undergoing partial mastectomy and concurrent reduction mammoplasty performe
76 ew board approval, patients undergoing total mastectomy and/or axillary lymph node dissection were ra
77 lumpectomy, unilateral mastectomy, bilateral mastectomy) and rates of additional surgery after initia
80 illary investigations, wait time to surgery, mastectomies, and contralateral prophylactic mastectomie
85 ss than 2 mm alone are not an indication for mastectomy, and factors known to impact rates of IBTR sh
86 lthough this was at the expense of increased mastectomies-and overall patient benefit from MRI in ILC
88 pingo-oophorectomy (RRBSO) and risk-reducing mastectomy are widely used for BRCA1 and BRCA2 mutation
90 ts (9.6%) underwent a bilateral prophylactic mastectomy at a median of 23 months following EOC diagno
93 diotherapy use for DCIS had increased use of mastectomy at the time of a second breast event even amo
94 h greater disease burden or those undergoing mastectomy, axillary dissection remains standard managem
95 The rate of positive margins after partial mastectomy (before randomization) was similar in the sha
97 atients with breast cancer who underwent 891 mastectomies between 2005 and 2013 were prospectively sc
98 l surgical procedure (lumpectomy, unilateral mastectomy, bilateral mastectomy) and rates of additiona
100 , breast conserving surgery (BCS), bilateral mastectomy (BLM), and unilateral mastectomy (ULM) was ab
101 o local or regional recurrence, frequency of mastectomy, breast cancer-specific survival, time to dis
102 portions of BCS-eligible patients undergoing mastectomy, breast reconstruction, and bilateral mastect
103 patients (4.9%) had a subsequent completion mastectomy, but no difference was found in the type of r
106 patients choosing contralateral prophylactic mastectomy, complications and procedure extent may be un
107 e growing rate of contralateral prophylactic mastectomy (CPM) among women diagnosed as having breast
108 process regarding contralateral prophylactic mastectomy (CPM) among women with sporadic breast cancer
110 emporal trends in contralateral prophylactic mastectomy (CPM) and determine whether survival differed
111 KGROUND: Rates of contralateral prophylactic mastectomy (CPM) have increased dramatically, particular
112 lines assert that contralateral prophylactic mastectomy (CPM) should be discouraged in patients witho
117 k women and mutation carriers, risk-reducing mastectomy decreased breast cancer by 85% to 100% and br
118 ter mastectomy was considered delayed if the mastectomy did not include IR or secondary if the mastec
121 ast-conserving therapy, mastectomy alone, or mastectomy followed by postmastectomy radiation therapy
123 dditional mammography (NX), one was found at mastectomy for another cancer (N0), and one was found at
125 bed complications in 14,894 women undergoing mastectomy for breast cancer from 1998 to 2007 and who u
127 Immediate breast reconstruction (IBR) after mastectomy for cancer has increased in recent years, yet
128 t study of temporal trends in performance of mastectomy for early-stage breast cancer using multivari
129 t for prophylactic mastectomy or therapeutic mastectomy for in situ breast cancer (78.6%; P < .001).
130 .05) and were more likely to be treated with mastectomy for larger tumors compared with women with PI
132 onservation is therapeutically equivalent to mastectomy for most patients with early-stage breast can
133 ever, women with PI were more likely to have mastectomy for smaller tumors; among women with tumors l
134 ology clinic among women planning to undergo mastectomy for stage I to III invasive ductal or lobular
135 oved outcomes, increasing rates of bilateral mastectomy for unilateral cancer have been observed in t
139 ncluded women aged 18 to 64 years undergoing mastectomy from January 1, 2004, through December 31, 20
142 the number of women undergoing risk-reducing mastectomy has increased rapidly in the USA in the past
143 such as soft tissue reconstruction following mastectomy; however, the ability of tumors to commandeer
144 mortality difference compared with bilateral mastectomy (HR, 1.02 [95% CI, 0.94-1.11]; 10-year mortal
145 in patients with these tumor features having mastectomy if the need for postmastectomy radiotherapy i
146 nserving therapy was performed in 656 (39%), mastectomy in 297 (17%) and mastectomy + postmastectomy
149 garding BCT was consistently documented, and mastectomy in BCT-eligible patients was largely the resu
150 ere seen in the trials of radiotherapy after mastectomy in node-positive disease (rate ratios, breast
151 I, 0.62 to 0.65), whereas radiotherapy after mastectomy in node-positive disease was associated with
158 mong 189,734 patients, the rate of bilateral mastectomy increased from 2.0% (95% CI, 1.7%-2.2%) in 19
161 Evidence indicates that increasing use of mastectomy is a patient-driven trend that is most pronou
163 l breast cancer, contralateral risk-reducing mastectomy is often, but not universally, indicated.
167 erentially around the cavity left by partial mastectomy) may reduce the rates of positive margins (ma
168 ients undergoing contralateral risk-reducing mastectomy might not be categorised as high risk and the
171 6.2%) and did not differ by treatment group (mastectomy only, 55.2% [15.0%]; mastectomy with reconstr
173 7%) had a calculated treatment preference of mastectomy only; 39 of these women (47.6%) underwent mas
176 ed that receipt of CPM (vs either unilateral mastectomy or breast conservation surgery) was significa
177 ed node-negative breast cancers treated with mastectomy or lumpectomy and radiation enrolled in the S
178 unilateral breast cancer who had undergone a mastectomy or lumpectomy with clear surgical margins.
179 d the increase was greatest for prophylactic mastectomy or therapeutic mastectomy for in situ breast
180 58 ex vivo samples from patients undergoing mastectomy or wide local excision, we demonstrate the pe
181 .7; P < .001), patients undergoing bilateral mastectomy (OR, 0.5; P < .001), or patients in the highe
182 % CI, 1.62-1.85), contralateral prophylactic mastectomy (OR, 1.48; 95% CI, 1.23-1.77), and a greater
183 tatic disease (OR, 1.51; 95% CI, 1.42-1.61), mastectomy (OR, 1.73; 95% CI, 1.62-1.85), contralateral
185 tion (breast-conserving therapy), unilateral mastectomy, or CPM, with subsequent subgroup analysis st
186 tion (breast-conserving therapy), unilateral mastectomy, or CPM, with subsequent subgroup analysis st
190 logic nodal status/breast tumor response; in mastectomy patients, they were clinical tumor size (befo
191 ients compared with only 16.0% of unilateral mastectomy patients, with rates of reconstruction with C
192 ients compared with only 16.0% of unilateral mastectomy patients, with rates of reconstruction with C
194 intestinal tract endoscopy (PFS, 26.5-34.3), mastectomy (PFS, 16.5-35.0), inguinal hernia repair (PFS
196 undergoing 5 outpatient procedures: partial mastectomy (PM), partial mastectomy with sentinel lymph
197 clinical factors, surgical approach (partial mastectomy [PM] or total mastectomy [TM]), and BCT failu
198 ed in 656 (39%), mastectomy in 297 (17%) and mastectomy + postmastectomy radiation therapy in 744 (44
199 C should not be the sole indication for post-mastectomy radiation, and accelerated delivery methods f
203 To study the impact of rising bilateral mastectomy rates among neoadjuvant chemotherapy (NAC) re
204 ence showed that MRI significantly increased mastectomy rates and suggests an unfavorable harm-benefi
206 dy examined the effect of insurance payer on mastectomy rates of 1539 women treated within a single h
207 y and is associated with positive margin and mastectomy rates that are low irrespective of the presen
208 surgical outcome (positive margin rates and mastectomy rates) of women with breast cancer who underw
211 1, 2016, at the 11 sites associated with the Mastectomy Reconstruction Outcomes Consortium Study.
214 egional lymph nodes, followed by an optional mastectomy scar boost of four fractions of 3.33 Gy.
219 n of the ROIs was significantly lower at the mastectomy site compared to the natural breast (p<0.01).
220 ndomly cued to palpate their natural breast, mastectomy site or breast reconstruction, and external s
227 en considered an indication for undergoing a mastectomy, this dictum may not apply in women with brea
228 e were no significant differences in time to mastectomy, time to distant metastasis, breast cancer-sp
229 l approach (partial mastectomy [PM] or total mastectomy [TM]), and BCT failure (initial PM followed b
230 on carriers) frequently undergo prophylactic mastectomy to minimize their risk of breast cancer.
231 mong all patients undergoing initial partial mastectomy, total mastectomy was performed in 190 patien
233 , bilateral mastectomy (BLM), and unilateral mastectomy (ULM) was abstracted from the medical records
234 r treatments combined, (2) CPM vs unilateral mastectomy (UM), and (3) CPM vs breast-conserving surger
237 r DCIS increased the likelihood of receiving mastectomy vs BCS at a subsequent breast event, even amo
238 ty, 16.8% [95% CI, 16.6%-17.1%]), unilateral mastectomy was associated with higher all-cause mortalit
245 95% CI, 1.04-1.22]); in contrast, unilateral mastectomy was more often used by racial/ethnic minoriti
249 undergoing initial partial mastectomy, total mastectomy was performed in 190 patients (8.5%; 95% CI,
257 n increasing number of patients are pursuing mastectomy, which may be followed by breast reconstructi
258 vised placement of an implant at the time of mastectomy while Surgeon B contrasted the pros and cons
259 ents with positive sentinel nodes undergoing mastectomy (who do not, as a standard, receive adjuvant
260 al carcinoma in situ (DCIS) who will undergo mastectomy, who previously underwent breast and/or axill
261 h ductal carcinoma in situ, who will undergo mastectomy, who previously underwent breast and/or axill
266 bidity were decreased in patients undergoing mastectomy with and without immediate breast reconstruct
269 o its independent effects on morbidity after mastectomy with immediate breast reconstruction are limi
270 ve cohort study of adult women who underwent mastectomy with immediate breast reconstruction from 200
272 upports the safety of NC in women undergoing mastectomy with or without immediate breast reconstructi
273 nt chemotherapy for surgical morbidity after mastectomy with or without reconstruction using 1:1 matc
274 tomy alone (hazard ratio, 1.31; P < .001) or mastectomy with radiation (hazard ratio, 1.47; P < .001)
275 inoma treated with BCT, mastectomy alone, or mastectomy with radiation during the period from 1998 to
276 with those treated with mastectomy alone or mastectomy with radiation for early-stage invasive ducta
277 alone was used to treat 27% of patients, and mastectomy with radiation was used to treat 3% of patien
278 who underwent BCT, a mastectomy alone, or a mastectomy with radiation were 97%, 94%, and 90%, respec
283 specifically, within the subgroup undergoing mastectomy with reconstruction, using multivariable line
289 5%) had a calculated treatment preference of mastectomy with reconstruction; 36 of these women (87.8%
290 aluate whether an approach combining partial mastectomy with reduction mammoplasty could provide a sa
291 procedures: partial mastectomy (PM), partial mastectomy with sentinel lymph node biopsy (PM SLNB), la
292 l cohort included 15,154 women who underwent mastectomy with tissue expander (TE: 70.5%), autologous
293 e were 2983 patients who underwent segmental mastectomy with whole-breast irradiation from 1987 to 20
294 f stage 0 to III who were undergoing partial mastectomy, with or without resection of selective margi
296 of overall morbidity in the group undergoing mastectomy without breast reconstruction (odds ratio [OR
297 mplete sample (OR, 0.59; 95% CI, 0.49-0.71), mastectomy without breast reconstruction (OR, 0.59; 95%
298 er overall morbidity in the group undergoing mastectomy without breast reconstruction (OR, 0.61; 95%
299 overall morbidity in the patients undergoing mastectomy without breast reconstruction and in those un
300 Of 85,851 women, 66,593 (77.6%) underwent mastectomy without breast reconstruction, with 2876 (4.3
301 963 underwent breast-conserving surgery, 263 mastectomy without reconstruction, and 222 mastectomy wi
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