ライフサイエンスコーパス: master regulator

1 genes, and identified ZNF800 as a candidate master regulator.

2 lly significant, we conclude that there is a master regulator.

3 ld not find any DNA-associated, strict sense master regulator.

4 ted receptor alpha1 (ERRalpha) mitochondrial master regulator.

5 ators and identifies biologically meaningful master regulators.

6 er by E6/E7, via a limited number of central master-regulators.

7 a well-established network biology approach (master regulator analysis) to combine a transcriptional

8 ed receptor gamma (PPARgamma), the adipocyte master regulator and receptor for the thiazolidinedione

9 of the UPR, and evidence indicates that the master regulators and downstream effectors of the UPR ha

10 atasets, our method ensures the existence of master regulators and identifies biologically meaningful

11 at cv Mitchell lacks the functional R2R3-MYB master regulator ANTHOCYANIN2 and has normally white flo

12 ion was primarily dependent on the virulence master regulator AphA.

13 ator LuxO is active and regulates the two QS master regulators AphA, which is induced, and OpaR, whic

14 However, recent studies indicate that the master regulators are often coexpressed.

15 ation, including a Candida albicans-specific master regulator at the CR1 locus.

16 o CD4(+) T cells, thereby enhancing Tfh cell master regulator Bcl-6 in a dendritic cell-dependent man

17 Conversely, conditional deficiency of the master regulator Bcl6 in CD4(+) T cells resulted in a ma

18 ive of GCB-DLBCL, including that of the GCB "master regulator," BCL6 (B-cell lymphoma 6).

19 e diverse family solves the problem of how a master regulator can control so many diverse receptors.

20 Furthermore, the expression of master regulators can be dynamic and quantitative.

21 nt developmental switches by transcriptional master regulators, chromatin state changes, and hormone

22 histocompatibility complex (MHC)-II and its master regulator class II transactivator (CIITA) are dow

23 MicroRNAs, gene expression master regulators, constitute an attractive candidate to

24 n, Lippi et al. (2016) identify miR-101 as a master regulator coordinating molecular programs during

25 ially distinct cell cycle events through the master regulator CtrA.

26 Therefore, CR3 serves as a master regulator during the antifungal neutrophil respon

27 tion of MAPK are transcriptionally linked to master regulators essential for neural stem cell identif

28 curs through the expression of the flagellar master regulator, FlhD4C2.

29 ne promoters, the promoters of the flagellar master regulator flhDC and mrp itself, appears to be aff

30 in this study, we have found that PU.1-a key master regulator for hematopoietic self-renewal and line

31 s can be classified as positive for Runx2, a master regulator for osteoblastogenesis.

32 , which inhibits the expression of ComK, the master regulator for the K-state, and reduces transforma

33 Fumarate and Nitrate Reduction (FNR) is the master regulator for the switch between anaerobic and ae

34 TFEB is a master regulator for transcription of genes involved in

35 gest that Oct4 competes with various lineage master regulators for binding promoters and enhancers.

36 ve been shown, in many cases, to function as master regulators for gene expression and thus, they can

37 We identified a small number of 'master regulators' for which downstream effector genes w

38 We use three such master regulators (FOXA1, NKX3.1 and androgen receptor,

39 t by decreasing acetylation of the Treg cell master regulator Foxp3 mediated by the histone acetyltra

40 indicating that Brachyury is not a notochord master regulator gene as strictly defined.

41 Our analyses identified 41 consensus master regulator genes (MRs), the regulons of which comp

42 This implicates putative master regulator genes in which multiple independent sto

43 Our data highlight SON as a master regulator governing neurodevelopment and demonstr

44 the unfolded protein response (UPR) negative master regulator Grp78 and an increase in the UPR.

45 the cadherin juxtamembrane domain acts as a master regulator guarding cadherin stability.

46 ing the regulatory structure and finding the master regulator help narrowing the search space for ide

47 tween HetP, its homologs, and the heterocyst master regulator, HetR, were assessed, and interaction p

48 s (i) a three-tiered hierarchy initiating at master regulators, (ii) high connectivity and (iii) dist

49 larmone (p)ppGpp has been determined to be a master regulator in B. burgdorferi.

50 es triggered by VLVs and found that PRDM1, a master regulator in cell differentiation, was significan

51 Progesterone receptor (PR) is a master regulator in female reproductive tissues that con

52 BES1 functions as a master regulator in the brassinosteroid (BR) pathway tha

53 ETV1 is a master regulator in the intestinal cells of Cajal (ICC),

54 ontrol strategies involving the targeting of master regulators in pathogens.

55 Ectopic expression of lineage master regulators induces transdifferentiation.

56 ctome was subsequently interrogated with the master regulator inference algorithm (MARINA) and gene e

57 lymphoma transformation signatures using the Master Regulator Inference algorithm (MARINa).

58 In fission yeast, the ste11 gene encodes the master regulator initiating the switch from vegetative g

59 e repression of the gastrointestinal lineage-master regulator Klf5.

60 hat act downstream of the embryo development master regulators LEAFY COTYLEDON 1 and 2, FUSCA 3, and

61 equired for symplasmata formation, including master regulator LrhA, replication inhibitor CspD, polys

62 conversion induced by the melanocyte lineage master regulator MITF.

63 TFDP1, ATF5, HMGA1, and NFYB to be candidate master regulators (MR) contributing to disease progressi

64 To further identify the Master Regulators (MRs) driving the network function, he

65 y distributed genomic island encoding tandem master regulators named FciA (for type four chromatic ac

66 ported that oncogenic Kras induced the redox master regulator Nfe2l2/Nrf2 to stimulate pancreatic and

67 in profile of photoreceptors lacking the rod master regulator Nrl is nearly indistinguishable from th

68 m we exhibit that in mESCs, the pluripotency master regulator Oct4, counteracts pro-differentiation i

69 synthetic genetic interaction with Hac1, the master regulator of a second proteotoxic stress response

70 ator-activated receptor gamma (PPARgamma), a master regulator of adipocyte differentiation, has recen

71 thways that supply ligands to Ppargamma, the master regulator of adipocyte homeostasis.

72 It is also the master regulator of adipogenesis.

73 pax6b and mnx1 while downregulating arxa, a master regulator of alpha-cell development and function.

74 We show here that the master regulator of amino acid homeostasis, activating t

75 The transcription factor, Nrf2 is a master regulator of anti-inflammatory and antioxidant ge

76 The Keap1/Nrf2 pathway is a master regulator of antioxidant, anti-inflammatory, and

77 n factor EB (TFEB) has recently emerged as a master regulator of autophagosome-lysosome function, con

78 ent by means of hepatic gene transfer of the master regulator of autophagy transcription factor EB or

79 or, Deleted in Colorectal Cancer (DCC), is a master regulator of axonal crossing throughout the neura

80 Furthermore, the activity of GSK3, a master regulator of beta-catenin degradation, is suppres

81 r (FXR) is a nuclear receptor that acts as a master regulator of bile acid metabolism and signaling.

82 fate of subplate neurons (SPNs), which are a master regulator of brain development that plays critica

83 Overall, our results highlight Wnt5a as a master regulator of brain invasion, specifically TPC, an

84 e affects the immune response by acting as a master regulator of carbohydrate metabolism in the infec

85 trol protein A (CcpA) is a highly conserved, master regulator of carbon source utilization in gram-po

86 Inducer of CBF expression 1 (ICE1) is a master regulator of CBFs, and ICE1 stability is crucial

87 The activation state of mTORC1, a master regulator of cell growth, is particularly sensiti

88 In eukaryotes, protein kinase A (PKA) is a master regulator of cell proliferation and survival.

89 the Notch/Delta-like ligand (Dll) pathway, a master regulator of cell-cell interaction and vascular p

90 mTORC1 is a signal integrator and master regulator of cellular anabolic processes linked t

91 The transcription factor Snail is a master regulator of cellular identity and epithelial-to-

92 target of rapamycin complex 1 (mTORC1) is a master regulator of cellular metabolism, growth, and pro

93 ly, we identified a novel role for Plk4, the master regulator of centriole duplication.

94 in regulation of expression of the critical master regulator of cholesterol biosynthesis, SREBP1.

95 identified the transcription factor SREBP2, master regulator of cholesterol homeostasis.

96 nding proteins (SREBPs) including SREBP-2, a master regulator of cholesterol synthesis.

97 ided with persistent expression of SOX9, the master regulator of chondrogenesis, and reducing SOX9 do

98 The transcription factor RpaA is the master regulator of circadian transcription in cyanobact

99 This study thus identifies Galectin-1 as a master regulator of clinically relevant inflammatory-res

100 Pantothenate kinase is the master regulator of CoA biosynthesis and is feedback-inh

101 containing miR-206, which represses Rrbp1, a master regulator of collagen biosynthesis, in fibrogenic

102 CITF1 acts together with a master regulator of copper homeostasis, SPL7 (SQUAMOSA P

103 spectrum disorders (ASD), including TBR1, a master regulator of cortical development.

104 ne of these direct targets is fruitless, the master regulator of courtship.

105 We propose that PRA is a master regulator of Cx43 expression, GJ formation and my

106 ption factor NRF2, encoded by NFE2L2, is the master regulator of defense against stress in mammalian

107 Missense mutations in ATM kinase, a master regulator of DNA damage responses, are found in m

108 llectively, this study identifies nRAGE as a master regulator of DSB-repair, the absence of which orc

109 own-regulated, T cell intrinsic S1PR1 is the master regulator of effector T-cell emigration from the

110 These results demonstrate that SurR is a master regulator of electron flow within P. furiosus, li

111 promotes optimal transcription of Wt1 as the master regulator of embryonic EPDCs.

112 e role of the transcription factor TWIST1, a master regulator of EMT, on cisplatin resistance in an E

113 n yeast) is an essential Hsp70 chaperone and master regulator of endoplasmic reticulum (ER) function.

114 The identification of this master regulator of endothelial and haematopoietic fate

115 osphate-activated protein kinase (AMPK) is a master regulator of energy homeostasis in eukaryotes.

116 or-activated receptor gamma (PPARgamma) is a master regulator of energy metabolism.

117 p63 is a master regulator of epidermal biology, sustaining stemne

118 e phytocalpain DEFECTIVE KERNEL1 (DEK1) is a master regulator of epidermal differentiation and mainte

119 nd homeobox transcription factor-1 (Zeb1), a master regulator of epithelial polarity, controls neuron

120 present in the promoter region of Grp78, the master regulator of ER stress, thereby preventing homeos

121 the top ranked target genes of EWS/FLI, the master regulator of ES, and is upregulated by EWS/FLI vi

122 The conserved small G-protein Cdc42 is a master regulator of eukaryotic cellular polarization.

123 gonadotropin-releasing hormone (GnRH) is the master regulator of fertility.

124 e predicted the microRNA-130/301 family as a master regulator of fibrotic pathways across a cohort of

125 n Gerbera hybrida, we show that GhUFO is the master regulator of flower meristem identity, while GhLF

126 As a master regulator of functional Ig heavy chain (IgH) expr

127 HIF-1alpha is a master regulator of gene expression and might play an im

128 a plays a dual role in the Golgi, serving as master regulator of Golgi organization and disorganizati

129 The master regulator of HBC activation is the DeltaN isoform

130 al. (2016) identify an interaction between a master regulator of heart development, TBX5, and the NuR

131 Thus, GATA4 acts as master regulator of hepatic microvascular specification

132 y the hermaphrodite-specific transcriptional master regulator of hermaphroditic cell identity tra-1,

133 organism, the histone deacetylase Sir2, the master regulator of heterochromatin, has acquired novel

134 t is a high zinc sensor in an animal and the master regulator of high zinc homeostasis.

135 n its cognate codon, ACG, including the DosR master regulator of hypoxic bacteriostasis.

136 Here, we identify IL-6 as a master regulator of IL-21 in effector CD8(+) T cells.

137 ng site for the aryl hydrocarbon receptor, a master regulator of IL-22 production.

138 , due to an impaired ability to activate the master regulator of inflammation, NF-kappaB.

139 Hepcidin, the master regulator of iron homeostasis, controls iron flow

140 as well as enhanced expression of MYC2, the master regulator of JA-dependent responses.

141 tivate the transcription factor EB (TFEB), a master regulator of lipid metabolism and lysosomal bioge

142 or 4-alpha (HNF4alpha) is a well established master regulator of liver development and function.

143 FMRP is a master regulator of local translation but its implicatio

144 Our data reveal that Rab29 is a master regulator of LRRK2, controlling its activation, l

145 n leading to the downregulation of Cited2, a master regulator of LSC quiescence.

146 regulator of shear responses, and PROX1, the master regulator of lymphatic development.

147 sed on the transcription factor EB (TFEB), a master regulator of lysosomal biogenesis that detects ly

148 le for the transcription factor EB (TFEB), a master regulator of lysosomal biogenesis, in this proces

149 ulation of transcription factor EB (TFEB), a master regulator of lysosomal pathways.

150 IL-1ss signaling and expression of CIITA, a master regulator of major histocompatibility class II ge

151 pression of the Elf5 transcription factor, a master regulator of mammary alveologenesis and luminal c

152 ion of Yap1 and beta-catenin may represent a master regulator of mechanical strain-induced cell proli

153 Upon nutritional starvation, the master regulator of meiosis Mei2 inactivates Mmi1, there

154 stripes and acts to directly repress Mitf, a master regulator of melanocyte differentiation, thereby

155 and Akt-NF-kappaB converging in MITF-M, the master regulator of melanomagenesis, were inhibited by D

156 e AMP-activated protein kinase (AMPK) is the master regulator of metabolic homeostasis by sensing cel

157 sential role as a cellular energy sensor and master regulator of metabolism in eukaryotes.

158 AMPK is a highly conserved master regulator of metabolism, which restores energy ba

159 rotein kinase (AMPK) is an energy sensor and master regulator of metabolism.

160 pharmacological inhibition of miRNA-10b - a master regulator of metastatic cell viability - leads to

161 al models, these findings show that DCC is a master regulator of midline crossing and development of

162 tein mitochondrial Rho GTPase 1 (Miro1) is a master regulator of mitochondrial axonal transport in re

163 PGC-1alpha is a master regulator of mitochondrial biogenesis and functio

164 controls the transcription of PGC-1alpha, a master regulator of mitochondrial biogenesis.

165 amma coactivator-1alpha (PGC-1alpha) gene, a master regulator of mitochondrial function.

166 The chromosome passenger complex (CPC) is a master regulator of mitosis.

167 lial cells identified a key role of GATA2 as master regulator of multiple endothelial functions via m

168 Transcription factor C/EBPalpha is a master regulator of myelopoiesis and its inactivation is

169 PAX7 is a master regulator of myogenesis that rescues DUX4-mediate

170 OD protein, a transcription factor that is a master regulator of myogenesis, while leaving MYOD mRNA

171 The circadian system is a master regulator of nearly all physiology and its disrup

172 7BL/6 mice increased expression of RIP3, the master regulator of necroptosis, as well as phosphorylat

173 E1)-silencing transcription factor (REST), a master regulator of neural genes.

174 NF-kappaB essential modulator (NEMO) is the master regulator of NF-kappaB signaling, controlling the

175 TnrA is a master regulator of nitrogen assimilation in Bacillus su

176 ite growth and define UNC-45A as a novel and master regulator of NMII-mediated cellular processes in

177 newal/differentiation, implicating TET2 as a master regulator of normal and malignant hematopoiesis.

178 abditis elegans was originally heralded as a master regulator of organ differentiation.

179 D1, via H3K4me1 demethylation, represses the master regulator of osteoblast differentiation RUNX2 to

180 Runx2, a master regulator of osteoblast differentiation, is tight

181 amma suppressed gene expression of NFATc1, a master regulator of osteoclastogenesis, whereas IL-12 in

182 esses ROS and tumor growth through FOXO3a, a master regulator of oxidative stress and superoxide dism

183 ind that cytosol acidification activates the master regulator of Pah1, the Nem1-Spo7 complex, thus li

184 strulation by ectopic expression of msgn1, a master regulator of paraxial mesoderm fate, or if transp

185 Here we identify Plk1 as a master regulator of PCP dynamics during mitosis.

186 suppresses expression of Krox20 (Egr2), the master regulator of PNS myelination.

187 gy 2 domain-containing protein (p66Shc) is a master regulator of reactive oxygen species (ROS).

188 1L is transcriptionally activated by NRF2, a master regulator of redox homeostasis.

189 tion were due to the activation of NRF2, the master regulator of redox stress tolerance.

190 The ATR kinase is a master regulator of replication stress responses.

191 Our data identify CRL2(Lrr1) as a master regulator of replisome disassembly during vertebr

192 ys an essential role in defense, whether the master regulator of SA signaling, NPR1, is targeted by a

193 We identified Srf as a master regulator of SC fusion required in both fusion pa

194 neutrophils with conditional deletion of the master regulator of selective autophagy, Wdfy3.

195 nal activation of ap2-g (PF3D7_1222600), the master regulator of sexual development, from an epigenet

196 tory mechanisms, imply that ZSCAN21 is not a master regulator of SNCA in vivo.

197 Many RNA-binding proteins including a master regulator of splicing in developing brain and mus

198 MICROSPORES (AMS) transcription factor is a master regulator of sporopollenin biosynthesis, secretio

199 Among these, HSF1, considered the master regulator of stress-induced transcriptional respo

200 Hepcidin is the master regulator of systemic iron homeostasis, facilitat

201 Hepcidin is the master regulator of systemic iron homeostasis.

202 The hepatic hormone hepcidin is the master regulator of systemic iron homeostasis.

203 cent evidence indicates the Wnt pathway as a master regulator of T cell immune responses via governin

204 Thus, SOX2 is a master regulator of the acinar cell lineage essential to

205 r (erythroid-derived 2)-like 2 (Nrf2) is the master regulator of the antioxidant response, and its fu

206 tor-erythroid 2-related factor-2 (Nrf2) is a master regulator of the antioxidant response.

207 ied the E-box transcription factor TCF4 as a master regulator of the BPDCN oncogenic program.

208 periments establish the ER Ca(2+) store as a master regulator of the Ca(2+) gradient response to epid

209 te a role for p53, a previously unrecognized master regulator of the cardiac transcriptome.

210 TOR is a master regulator of the cell's growth and metabolic stat

211 e upon the hypoxia-inducible factor (HIF), a master regulator of the cellular adaptive response to hy

212 The transcription factor NRF2 is a master regulator of the cellular antioxidant response, a

213 sed by mutations in the gene-encoding ATM, a master regulator of the DNA damage response.

214 e the method by analysing the control of the master regulator of the E. coli stress response, RpoS, b

215 NRF2 is a transcription factor serving as a master regulator of the expression of many genes involve

216 sitive effect on the expression of rpoS, the master regulator of the general bacterial stress respons

217 HSF1 is the supposed master regulator of the heat shock response.

218 aken together, these data identify E4F1 as a master regulator of the PDC.

219 al mediator of sterile inflammation, to be a master regulator of the prothrombotic cascade involving

220 ritional enrichment in mammals but is also a master regulator of the spatiotemporal signaling events

221 ated orphan receptor gammat (RORgammat) is a master regulator of the Th17/IL-17 pathway that plays cr

222 The hypoxia-inducible factor (HIF) is the master regulator of the transcriptional response to hypo

223 show that pharmacologic modulation of GRP78, master regulator of the unfolded protein response in the

224 GRP78, also called BiP, is a master regulator of the UPR, reducing ER stress levels a

225 ed into the thermogenic program by PRDM16, a master regulator of thermogenesis.

226 gulation, identify a previously unrecognized master regulator of this critical immune checkpoint and

227 ntify Pib2 (PhosphoInositide-Binding 2) as a master regulator of TORC1.

228 ses from disruption of the role of EZH2 as a master regulator of transcription.

229 covered a unique retained intron (RI) in the master regulator of translation initiation, EIF2B5.

230 ops acting on the transcription of WOR1, the master regulator of white-opaque switching, but regulati

231 lcium is a known potent second messenger and master regulator of wound-healing programs, it is unknow

232 onse modules and their role in orchestrating master regulators of adaptive responses.

233 based on the [Formula: see text] system are master regulators of an array of cellular responses.

234 Expression of the master regulators of B cell development Ebf1 and Pax5 wa

235 ds of recognition sites in common with known master regulators of cell cycle-dependent gene expressio

236 interplays between cell cycle machinery and master regulators of cell fate choice remain to be fully

237 The members of the Rab family of GTPases are master regulators of cellular membrane trafficking.

238 cin (mTOR) complexes, mTORC1 and mTORC2, are master regulators of cellular survival, growth and metab

239 RNA-binding proteins (RBPs) are master regulators of co- and post-transcriptional events

240 unt-related transcription factors (RUNX) are master regulators of development and major players in tu

241 hat poising the fast-activating enhancers of master regulators of differentiation through continual h

242 As master regulators of ferroptotic cell death with profoun

243 unexpected identification of BET proteins as master regulators of global transcription elongation.

244 nd PPARgamma, transcription factors that are master regulators of hepatocyte and adipocyte differenti

245 ariants tend to occur near binding sites for master regulators of immune differentiation and stimulus

246 As in mammals, CD4-1(+) T cells may be the master regulators of immune responses in fish, and there

247 homeostasis and proper expression of several master regulators of iron metabolism, including iron reg

248 We found that MiT/TFE transcription factors-master regulators of lysosomal and melanosomal biogenesi

249 hibit the expression of FOXM1 and CENPF, two master regulators of metastasis in PCa.

250 INT-777 also induced renal expression of master regulators of mitochondrial biogenesis, inhibitor

251 nd show that these transcription factors are master regulators of neuropsychiatric function.

252 Furthermore, master regulators of Oncopig STS expression were identif

253 on of PRDM1, IRF4, and XBP1, transcriptional master regulators of plasma cell (PC) differentiation.

254 we have described roles for these kinases as master regulators of pro-inflammatory gene expression in

255 Rho GTPases are master regulators of the eukaryotic cytoskeleton.

256 Members of the Rab GTPase family are master regulators of vesicle trafficking.

257 from the extracellular matrix converges on "master" regulators of autophagy including AMPK and mTORC

258 MKP-1 serves as a master-regulator of macrophage phenotype and function an

259 or (erythroid-derived 2)-like 2 (Nrf2), the "master regulator" of genes controlling cellular redox ho

260 Although Aurora B is regarded as the "master regulator" of kinetochore-microtubule attachment,

261 Heat shock factor 1 (HSF1), the "master regulator" of the HSR, controls only a fraction o

262 Prp8 has long been considered the "master regulator" of the spliceosome, the molecular mach

263 In addition to identifying the master regulator our method provides an overview of the

264 ated by the pioneer transcription factor and master regulator PHA-4/FoxA, followed by the cytoskeleta

265 Moreover, in BIRD-1, mutagenesis of the master regulator, phoBR, led us to confirm the addition

266 ion factors phosphorylated SP1 and NFAT were master regulators promoting or inhibiting EMT, respectiv

267 he effects of depletion of the developmental master regulator PTF1A on the specialized phenotype of t

268 propose that this response is driven by the master regulator retinoic acid receptor-related orphan r

269 of cancer cells and specifically inhibit the master regulator serine/threonine protein kinase CK2 and

270 ChIP-seq analysis for the master regulator STAT5A, the glucocorticoid receptor, H3

271 he recruitment of RSC at the promoter of the master regulator ste11 gene.

272 nd were regulated by chloroplast maintenance master regulators such as GLK1.

273 targets of lineage-specific transcriptional master regulators such as p63.

274 l differentiation genes together with B-cell master regulators such as PAX5, EBF1, and IRF4 but is re

275 further demonstrate that conserved CREs bind master regulators, suggesting that while CREs contribute

276 t invertebrate embryos; second, the dueling 'master regulator' systems that are commonly used to expl

277 ated transcription factor) and the lysosomal master regulator TFEB, had the highest phylogenetic cons

278 oma (RB) tumor suppressor is recognized as a master regulator that controls entry into the S phase of

279 A: diacylglycerol kinase kappa (Dgkkappa), a master regulator that controls the switch between diacyl

280 The transcription factor GATA3 is the master regulator that drives mammary luminal epithelial

281 ubiquitin-specific peptidase 13 (USP13) as a master regulator that drives ovarian cancer metabolism.

282 (TOR) kinase is an evolutionarily conserved master regulator that integrates nutrient and energy sig

283 Our results establish HMGB2 as a novel master regulator that orchestrates SASP through preventi

284 tor erythroid 2-related factor 2 (Nrf2) is a master regulator that promotes the transcription of cyto

285 unknown, it is likely that some of the same master regulators that drive EMT and MET in carcinomas a

286 III Ca(2+)-sensor protein kinases (CPKs) as master regulators that orchestrate primary nitrate respo

287 ant is the stable and heritable silencing of master regulators that would specify alternative lineage

288 can identify cell type specification genes (master regulators) that act synergistically, and demonst

289 ial role of the actin network and one of its master regulators, the small GTPase Cdc42, during Junin

290 , it is important to identify and target the master regulator transcription factor for proper underst

291 computational approach for identification of master regulator transcription factor in a genome.

292 our method we test whether there exists any master regulator transcription factor in the system.

293 t the second step, our method identifies the master regulator transcription factor, if there exists o

294 This 'master regulator' transcription factor is at the top of

295 loped a screening method of identifying the 'master regulator' transcription factor just using only t

296 A 'master regulator' transcription factor often appears to

297 expression profile similar to the mesodermal master regulator Twist.

298 ne thizole synthase and CP12, a Calvin Cycle master regulator, were uniformly up-regulated.

299 onably well in validating the existence of a master regulator when the number of subjects in each tre

300 l perturbations were minimized; as a pair of master regulators when low oxygen tension was sensed, th