ライフサイエンスコーパス: maximal level

1 o a 2- to 3-fold increase in NPY production (maximal level).

2 rst 2-3 weeks and thereafter remains at that maximal level.

3 whereas IL-4 was induced to one third of its maximal level.

4 dNTP concentration does not exceed a certain maximal level.

5 l level, 8 h was required for induction of a maximal level.

6 -deficient mice restored Ad5 transduction to maximal levels.

7 A2 mRNA, with 15 to 18 AGAT repeats yielding maximal levels.

8 ind GR homodimer and induce transcription to maximal levels.

9 ase inhibitors, but was necessary to achieve maximal levels.

10 removal, while saline-pretreated rats showed maximal levels 100-140 min after TMT removal.

11 ft IL-2 and IL-12 (p40) mRNAs, which reached maximal levels 3 to 6 h post-transplantation.

12 rescence signal from cleaved CNIR800 reaches maximal levels 4-6 hours after administration in live an

13 NF exposure induced NPY production at a half maximal level, 8 h was required for induction of a maxim

14 tion of both MMPs by RNK-16 cells attained a maximal level after 24 h of incubation and was enhanced

15 onary inflammatory response that reaches its maximal level after four challenges.

16 In liver and kidney, HIF-1alpha reaches maximal levels after 1 h and gradually decreases to base

17 ident 5 minutes after injection, and reached maximal levels after 25 minutes (+107% versus vehicle, P

18 pid induction of cGMP by IL-1, which reached maximal levels after 5 min.

19 B levels showed a delayed response, reaching maximal levels after 6 h.

20 Mast cell cAMP reached maximal levels after 90 s and did not further increase o

21 that CaMKII autonomous activity reached near maximal levels after approximately 45 impulses, regardle

22 Phosphorylation of MEI-1 by MBK-2 reaches maximal levels after the meiotic divisions, immediately

23 otides increases targeting frequency up to a maximal level and then it decreases.

24 coupling of the three receptor variants to a maximal level approaching that of wild type MOR.

25 ally low but subsequently increases to reach maximal levels around weaning.

26 reactivity at low food conditions to similar maximal levels as observed under high food conditions an

27 e expression rapidly increased and reached a maximal level at 0% air.

28 EGF-induced Erk-2 activation reached a maximal level at 15 minutes, followed by a decline towar

29 ew as approximately 10 repeats and reaches a maximal level at 30 to 40 repeats.

30 Thy-1 levels reached a maximal level at approximately postnatal day 14.

31 as observed in the two-cell stage, reached a maximal level at the early blastocyst stage, and decreas

32 n accumulates during development, reaching a maximal level at the finger stage.

33 in the medium increased at 10 min, reaching maximal levels at 1 and 20 h.

34 ited a delay in IGF-II mRNA expression, with maximal levels at 10 days after wounding.

35 , CYP2J5 is present before birth and reaches maximal levels at 2-4 weeks of age.

36 sive element binding protein (CREB), reached maximal levels at 3 months and were strongly correlated

37 exudates, MaR1 was temporally regulated with maximal levels at 4 h (2.2 +/- 0.4 pg/lavage).

38 ccurred in a time-dependent manner, reaching maximal levels at 4 to 7 h.

39 Mucosal IFN-gamma mRNA also reached maximal levels at 4 weeks but remained high thereafter.

40 induction tau expression increased, reaching maximal levels at 5 to 7 days.

41 The serum mineral complex reaches maximal levels at 6 h after subcutaneous injection of et

42 d MME mRNA in a time-dependent fashion, with maximal levels at 6 h.

43 This activation was rapid, reaching maximal levels at 60 min, and was dependent on the numbe

44 ging activities that were stimulated to half-maximal levels at about 3 microM ATP, indicating that th

45 e model legume Medicago truncatula, reaching maximal levels at around 20 d after pollination.

46 ly expressed with the cell cycle and reaches maximal levels at G1/S.

47 ncrease markedly until after birth, reaching maximal levels at P11-P24.

48 + tumor necrosis factor alpha; however, the maximal level attained in Ras transformants was approxim

49 ells, which is detectable within 30 min with maximal levels attained after 4 h.

50 .2), 10(2.8), and 10(3.4), respectively) and maximal levels being detected between 7 and 14 days afte

51 ern analysis showed that ComS accumulates to maximal levels between T3 and T4, mirroring the pattern

52 eclining steadily thereafter to 20% of their maximal level by 9 weeks of age.

53 DNA strand breaks, with both increasing to a maximal level by day 3 after activation.

54 y reflecting total MAP2 expression reaches a maximal level by postnatal day 20 (P20).

55 peritoneal IVM injection (10 mg/kg), reached maximal levels by 12 hr, and was almost fully reversed b

56 ing in the nuclei within 30 min and reaching maximal levels by 1h.

57 HT by human lamina propria T cells, reaching maximal levels by 2-6 h, whereas peripheral blood or lym

58 gnificantly increased at 30 min, and reached maximal levels by 24 h.

59 lasma and whole blood (125)I-PrP(Sc) reached maximal levels by 30 min and 3 hr, respectively, and blo

60 n of IgG immune complex deposition, reaching maximal levels by 4 h, whereas Stat3 activation was foun

61 n the first 2 h after MMC treatment, reached maximal levels by 6 h, and decreased progressively there

62 globotetraosylceramide (Gb4) levels reached maximal levels by 6 months of age and then rapidly decre

63 crease at 1 h after UVB exposure and reached maximal levels by 8-12 h.

64 environment within 2 d of injury and reaches maximal levels by day 4.

65 5 and increased during development, reaching maximal levels by postnatal day 7.

66 rowth, tumor-specific CTL response reaches a maximal level during progressive tumor growth, and tumor

67 thermore, expression of BMP2 in vivo reaches maximal levels during the period of gliogenesis.

68 s showed high seroconversion rates, reaching maximal levels early in childhood, whereas others did no

69 otor unit activation pattern associated with maximal-level eccentric muscle actions.

70 D6) expression is cell cycle regulated, with maximal levels expressed in late S/G2 phases of the cell

71 roductive binding site for imidazole, with a maximal level for the rate constant of proton transfer n

72 used at microdialysis sites to raise SkBF to maximal levels for data normalization.

73 umor core and invasive rim regions, with the maximal levels found in the invading glioma cells locate

74 c was released into the cytoplasm only after maximal levels had been reached in the mitochondria, but

75 essed at a low level in the Bvg+ phase, at a maximal level in the Bvg(i) phase, and at undetectable l

76 the early trophozoite stage and reaches its maximal level in the late trophozoite and schizont stage

77 helical gp41 trimers, increased rapidly to a maximal level in the primed state but decreased once sta

78 EIPIN3 have broader expression profiles with maximal levels in embryos and pollen, where LDs accumula

79 illate during the osteoblast cell cycle with maximal levels in G(1).

80 rogram . kg(-1) . min(-1)) increased LVEF to maximal levels in G(s)alpha x403 and G(s)alpha, whereas

81 levated levels of ID1 in NSCLC samples, with maximal levels in metastatic lung cancers.

82 5-hydroxymethylcytosine (5hmC) occurs at maximal levels in postmitotic neurons, where its accumul

83 AFB(1)-FAPY is detected at near maximal levels in rat DNA days to weeks after AFB(1) exp

84 is inactive in the duodenum and expressed at maximal levels in the distal small bowel.

85 ORA59 transcript levels do not reach maximal levels in the tga2 tga5 tga6 triple mutant, and

86 njection of 40 microg/mouse to 37-54% of the maximal level induced by a 1 microg/mouse injection of L

87 ence of all fibroblasts, although not to the maximal levels induced by fibroblasts.

88 We show that cell volume reaches the same maximal level irrespective of the osmolality of the medi

89 also regulated with the cell cycle, reaching maximal levels just before the onset of DNA synthesis.

90 els by cell adhesion, and remained at nearly maximal levels longer than wild-type activity.

91 ultivated oat), AV1, AV10 and Z1 mRNAs reach maximal levels midway through seed development but fall

92 ) with a similar time course and to the same maximal level observed in WT cells (85%).

93 , and its insulin responsiveness rose to the maximal levels observed in fully differentiated adipocyt

94 ells) on or before day 18 and increased to a maximal level of 2 ng/72 h by day 30.

95 T cells within 8 h of triggering, reaching a maximal level of 60% of control by 24 h.

96 erfusion further activated p38 MAPK, and the maximal level of activation (6.3-fold, P<0.01) was reach

97 At the maximal level of activation by GCAP, this isozyme alone

98 Amiodarone enhanced the maximal level of agonist-stimulated release of arachidon

99 only tyrosine 343 or tyrosine 464 supports a maximal level of AP-1 activation.

100 The maximal level of attenuation within normal lung was 18.5

101 However, the maximal level of bromodeoxyuridine incorporation is redu

102 abuse or dependence, current alcohol use, or maximal level of cannabis, sedative, stimulant, or cocai

103 This latter parameter is defined as the maximal level of cocaine at which the probability of sel

104 ensitivity, apparent affinity for RetGC, and maximal level of cyclase activation.

105 el of AHR resulted in a 50% reduction in the maximal level of CYP1A1 induced by 2,3,7,8-tetrachlorodi

106 while the trigeminal motor nucleus reached a maximal level of expression around P18.

107 Starting from a maximal level of expression at the time of adult emergen

108 s a unique pattern of expression, having its maximal level of expression in skeletal muscle.

109 activators working in concert to confer the maximal level of expression, but the mechanism of such s

110 ich removed hydrogen peroxide even after the maximal level of ferrylHb was reached.

111 oking were significant predictors of reduced maximal level of FEV(1) in males but not in females.

112 The maximal level of force development was dramatically decr

113 hins for 3 d was sufficient to establish the maximal level of functional synapses.

114 The maximal level of hHcsA expression was observed in late G

115 ties of Treg cells are required to achieve a maximal level of immune suppression.

116 eplication and subsequent establishment of a maximal level of latency.

117 centrations as low as 5 microM, and the half-maximal level of NarX autophosphorylation occurred at ap

118 The maximal level of NO produced by human macrophages was no

119 nding to Cdk2-cyclin E occurred at 12 h; the maximal level of p27 phosphorylation at Thr-187 in the t

120 ecreased the rate of phosphorylation and the maximal level of phosphoenzyme.

121 y increasing mouth air leak and reducing the maximal level of pressure that can be tolerated.

122 We now report that the maximal level of receptor-mediated second messenger sign

123 In at least some of the cases, the maximal level of sensitivity that was obtained could not

124 Pancreatitis reaches its maximal level of severity within 24 h of induction, and

125 ven repeated injections of toxin so that the maximal level of toxin was maintained for a sustained pe

126 The maximal level of TRPV5 current density stimulated by the

127 capacity as indicated by AS sensitivity and maximal level of vir-inducing activity at saturating AS

128 roduced in a luxS-dependent manner, reaching maximal levels of 2.5 muM in the late logarithmic growth

129 t increase of [3H]thymidine incorporation to maximal levels of 46.3 +/- 3.6% and 12.3 +/- 1.6% (P < 0

130 In contrast, the maximal levels of activated Stat1alpha produced by monov

131 transcription start site) was necessary for maximal levels of activity.

132 10 mg DBM in the in vitro model provided for maximal levels of ALP in cell extracts.

133 In this study, we confirm that the maximal levels of alpha-profibrin found over the course

134 to transform thrombin to its slow form, the maximal levels of alpha-profibrin rose to those expected

135 insc mRNA transcripts in neuroblasts confers maximal levels of apical Insc activity, which is require

136 vity in A375 anti-Fas-treated cells preceded maximal levels of apoptosis.

137 and for the ensuing activation, whereas the maximal levels of binding and activation attained at sat

138 Maximal levels of binding, activation, and apoptosis wer

139 In contrast, IL-4 knockout mice developed maximal levels of both mucosal and systemic immune prote

140 ppa B activation and Gal1-R expression, with maximal levels of both observed 3 days after gavage.

141 Maximal levels of CAF activity were not observed until 5

142 CAT virus infects a variety of tissues, with maximal levels of CAT gene expression found in the liver

143 HOECs secrete maximal levels of CCL20 at 6 h, following stimulation by

144 nstitutive response on transfection, whereas maximal levels of constitutive activity ranging from 30

145 al conditions of oligonucleotide uptake, the maximal levels of correct human beta-globin mRNA and hem

146 Viable S. aureus and Salmonella induced maximal levels of CSF mRNA expression and cytokine secre

147 Maximal levels of DAKAP200 are detected in the pupal pha

148 es grown in F-12K/serum medium revealed that maximal levels of DARP were detected on culture day 6 wi

149 In general, maximal levels of DNA scission (i.e. Cmax) varied over a

150 e levels that was temporally shifted so that maximal levels of dopamine were significantly higher and

151 inversely with Cmax values, indicating that maximal levels of etoposide-induced scission reflect the

152 ower buds is developmentally regulated, with maximal levels of expression coinciding with anthesis, w

153 We show that HS5-1 is required for maximal levels of expression from the Pcdh alpha1-12 and

154 odes a protein, Fat1p, which is required for maximal levels of fatty-acid import and has an acyl CoA

155 lantation as in the ex vivo experiment, with maximal levels of gene expression in endothelial cells o

156 t led to an increase in both the potency and maximal levels of gene expression induced by rapamycin,

157 Primary vaccine recipients had maximal levels of granulocyte-colony-stimulating factor

158 id transcription, while E74A is required for maximal levels of hid induction.

159 9 insect cells with recombinant baculovirus, maximal levels of Hsp72 protein were detected.

160 levels of IL-4 (<100 pg/ml) but much higher maximal levels of IFN-gamma than did Ag-specific B cells

161 Similar maximal levels of IL-22 transcripts could be induced in

162 moter (LSP) and the HSP1 promoters displayed maximal levels of in vitro transcription when TFAM was p

163 At maximal levels of induction it is one of the most abunda

164 increases to three out of the four sites at maximal levels of inhibition and quenching in phosphate

165 d peroxidation was observed rapidly and half-maximal levels of lipid peroxidation were reached at a 1

166 The maximal levels of lysis with Gag-, reverse transcriptase

167 a method that enables the prediction of the maximal levels of mRNA expression in Escherichia coli wi

168 r seconds initiated neuronal cell death, but maximal levels of neuronal cell death were observed with

169 dogenous miR-155 controlled the kinetics and maximal levels of PD-L1 induction upon IFN-gamma and TNF

170 load-recruitable stroke work failed to reach maximal levels of performance in GAMT-/- hearts (101+/-8

171 s time- and temperature-dependent, depresses maximal levels of pigment dispersion, and is therefore l

172 levels were increased by LPS at a time when maximal levels of plasma TNF-alpha were observed in both

173 the six genes that were studied resulted in maximal levels of PLF as quickly as 30 min following inf

174 Maximal levels of pro-B cell expansion, generally result

175 are the first to demonstrate that less than maximal levels of receptor phosphorylation can block G p

176 ically discernible axial elements and SC and maximal levels of recombination.

177 1.5-cm) intrarenal cysts are scanned during maximal levels of renal parenchymal enhancement.

178 m region of about 50 bp that is required for maximal levels of replication.

179 Maximal levels of resistance correlate not with maximal

180 1 to the perinuclear region began only after maximal levels of RNA synthesis had been achieved, excep

181 min earlier in the cocaine-pretreated group (maximal levels of saline controls=378% increase, cocaine

182 rotecting group leads to the conclusion that maximal levels of screw-sense preference are induced by

183 The temporal regulation and maximal levels of SMI-32 and SMI-31 expressions on MF ta

184 al cell monolayers stimulated by thrombin to maximal levels of static sickle erythrocyte adherence al

185 rnative regulatory mechanisms are engaged at maximal levels of stimulation.

186 An unexpected finding was that even at maximal levels of TCR engagement and CD28-mediated costi

187 ncy of responding cells (particularly at sub-maximal levels of TCR engagement), and more prominently,

188 protein, and rates of CE formation, but not maximal levels of TGase protein.

189 urred slightly earlier than for IL-6 because maximal levels of TNF alpha were detected 2 to 3 days af

190 s from cellular systems, we demonstrate that maximal levels of transactivation in vitro require both

191 sidue at position 52 of CRP is inhibitory to maximal levels of transcription activation from Class II

192 Maximal levels of transcription was achieved when two PE

193 Maximal levels of transcriptional synergy between these

194 and oleate required either Fat1p or FATP for maximal levels of transport.

195 Nuclease protection assays showed maximal levels of TrkB and synapsin I mRNAs in the hippo

196 In neuronal channels, the maximal levels of uptake for W45A/S/F are about 50% thos

197 Maximal levels of VCL and VERL were found in February 20

198 Maximal levels of Xbra expression are attained using low

199 s were detected during infection, reaching a maximal level on day 3.

200 d by progesterone in pregnant mice, reaching maximal levels on day 12.5 of pregnancy.

201 The SMM concentration reached maximal levels on day 2 of the post-treatment period for

202 TMP reached maximal levels on day 3 after drug administration for do

203 All of these UPR events reach maximal levels once Ig synthesis and secretion are marke

204 e activity increased more slowly and reached maximal levels only after 20 h of exposure, leading to a

205 3 to sensitized rats restored phospho-ERK to maximal levels only in MPC when examined 7 d later.

206 employed increases basal p70 activity to the maximal level otherwise attained in the presence of insu

207 The maximal level released was about 0.105 mg/dm(2), which i

208 els required >24-h incubation, that reaching maximal levels required at least 18 h of cytokine treatm

209 s their concentration to 7% and 10% of their maximal level, respectively, strongly suggesting that de

210 the presence of either Mn(2+) or Mg(2+) with maximal levels seen with 10-20 mM Mn(2+).

211 ge-rich lesions increased faster and reached maximal levels several fold higher than in the macrophag

212 At their maximal levels, state practice prerogatives authorized a

213 be and insufflated the colon with air to the maximal level that the patient could tolerate.

214 bFGF stimulated DNA synthesis to the same maximal level under both conditions, but chlorate-treate

215 sustained an isometric elbow flexion at 30% maximal level until exhaustion while their brain (EEG) a

216 Binding was near maximal levels up to 1.6 kb away from parS, and signific

217 ificant lag before mRNA levels increased; 2) maximal levels were not reached until 48-72 h after the

218 odest when DROJ1 was depleted alone, reached maximal levels when DROJ1 and HSP70/HSC70, or DROJ1 and

219 mes; the mass of NGF decreased to 10% of the maximal level within 2-3 mm of the polymer matrix.

220 ulin M (IgM) and IgG were produced to almost maximal levels within 1 week of a single immunization.

221 pupal commitment on day 3 and is induced to maximal levels within 12h by low levels of 20-hydroxyecd

222 e smooth muscle-like cells (BC3H1), reaching maximal levels within 3 to 4 min.

223 e cells) or with thymine dimers increased to maximal levels within 30 min after UVB.

224 Some genes are expressed at near-maximal levels within 30 min, whereas others show no sub

225 within 10 minutes of stimulation and reached maximal levels within 60 minutes.