ライフサイエンスコーパス: maximal level

1 o a 2- to 3-fold increase in NPY production (maximal level).

2 rst 2-3 weeks and thereafter remains at that maximal level.

3 whereas IL-4 was induced to one third of its maximal level.

4 dNTP concentration does not exceed a certain maximal level.

5 l level, 8 h was required for induction of a maximal level.

6 built up over tens of seconds until reaching maximal levels.

7 Mec1, and peaks after Mec1 activity reaches maximal levels.

8 -deficient mice restored Ad5 transduction to maximal levels.

9 antigenic stimulation over several days for maximal levels.

10 A2 mRNA, with 15 to 18 AGAT repeats yielding maximal levels.

11 ind GR homodimer and induce transcription to maximal levels.

12 ase inhibitors, but was necessary to achieve maximal levels.

13 removal, while saline-pretreated rats showed maximal levels 100-140 min after TMT removal.

14 ft IL-2 and IL-12 (p40) mRNAs, which reached maximal levels 3 to 6 h post-transplantation.

15 rescence signal from cleaved CNIR800 reaches maximal levels 4-6 hours after administration in live an

16 NF exposure induced NPY production at a half maximal level, 8 h was required for induction of a maxim

17 fore Abeta deposition reaches critical (half-maximal) levels, a phenomenon reminiscent of the two pat

18 tion of both MMPs by RNK-16 cells attained a maximal level after 24 h of incubation and was enhanced

19 onary inflammatory response that reaches its maximal level after four challenges.

20 In liver and kidney, HIF-1alpha reaches maximal levels after 1 h and gradually decreases to base

21 ident 5 minutes after injection, and reached maximal levels after 25 minutes (+107% versus vehicle, P

22 pid induction of cGMP by IL-1, which reached maximal levels after 5 min.

23 B levels showed a delayed response, reaching maximal levels after 6 h.

24 Mast cell cAMP reached maximal levels after 90 s and did not further increase o

25 that CaMKII autonomous activity reached near maximal levels after approximately 45 impulses, regardle

26 Phosphorylation of MEI-1 by MBK-2 reaches maximal levels after the meiotic divisions, immediately

27 otides increases targeting frequency up to a maximal level and then it decreases.

28 letion of Gpr35 increased baseline Ca(2+) to maximal levels and reduced Src activation and overall me

29 coupling of the three receptor variants to a maximal level approaching that of wild type MOR.

30 ally low but subsequently increases to reach maximal levels around weaning.

31 reactivity at low food conditions to similar maximal levels as observed under high food conditions an

32 e expression rapidly increased and reached a maximal level at 0% air.

33 EGF-induced Erk-2 activation reached a maximal level at 15 minutes, followed by a decline towar

34 ew as approximately 10 repeats and reaches a maximal level at 30 to 40 repeats.

35 Thy-1 levels reached a maximal level at approximately postnatal day 14.

36 as observed in the two-cell stage, reached a maximal level at the early blastocyst stage, and decreas

37 n accumulates during development, reaching a maximal level at the finger stage.

38 in the medium increased at 10 min, reaching maximal levels at 1 and 20 h.

39 ited a delay in IGF-II mRNA expression, with maximal levels at 10 days after wounding.

40 , CYP2J5 is present before birth and reaches maximal levels at 2-4 weeks of age.

41 sive element binding protein (CREB), reached maximal levels at 3 months and were strongly correlated

42 exudates, MaR1 was temporally regulated with maximal levels at 4 h (2.2 +/- 0.4 pg/lavage).

43 ccurred in a time-dependent manner, reaching maximal levels at 4 to 7 h.

44 Mucosal IFN-gamma mRNA also reached maximal levels at 4 weeks but remained high thereafter.

45 induction tau expression increased, reaching maximal levels at 5 to 7 days.

46 The serum mineral complex reaches maximal levels at 6 h after subcutaneous injection of et

47 d MME mRNA in a time-dependent fashion, with maximal levels at 6 h.

48 This activation was rapid, reaching maximal levels at 60 min, and was dependent on the numbe

49 ging activities that were stimulated to half-maximal levels at about 3 microM ATP, indicating that th

50 e model legume Medicago truncatula, reaching maximal levels at around 20 d after pollination.

51 ly expressed with the cell cycle and reaches maximal levels at G1/S.

52 ncrease markedly until after birth, reaching maximal levels at P11-P24.

53 + tumor necrosis factor alpha; however, the maximal level attained in Ras transformants was approxim

54 ells, which is detectable within 30 min with maximal levels attained after 4 h.

55 .2), 10(2.8), and 10(3.4), respectively) and maximal levels being detected between 7 and 14 days afte

56 ern analysis showed that ComS accumulates to maximal levels between T3 and T4, mirroring the pattern

57 eclining steadily thereafter to 20% of their maximal level by 9 weeks of age.

58 DNA strand breaks, with both increasing to a maximal level by day 3 after activation.

59 y reflecting total MAP2 expression reaches a maximal level by postnatal day 20 (P20).

60 peritoneal IVM injection (10 mg/kg), reached maximal levels by 12 hr, and was almost fully reversed b

61 ing in the nuclei within 30 min and reaching maximal levels by 1h.

62 HT by human lamina propria T cells, reaching maximal levels by 2-6 h, whereas peripheral blood or lym

63 gnificantly increased at 30 min, and reached maximal levels by 24 h.

64 lasma and whole blood (125)I-PrP(Sc) reached maximal levels by 30 min and 3 hr, respectively, and blo

65 n of IgG immune complex deposition, reaching maximal levels by 4 h, whereas Stat3 activation was foun

66 n the first 2 h after MMC treatment, reached maximal levels by 6 h, and decreased progressively there

67 globotetraosylceramide (Gb4) levels reached maximal levels by 6 months of age and then rapidly decre

68 crease at 1 h after UVB exposure and reached maximal levels by 8-12 h.

69 environment within 2 d of injury and reaches maximal levels by day 4.

70 5 and increased during development, reaching maximal levels by postnatal day 7.

71 rowth, tumor-specific CTL response reaches a maximal level during progressive tumor growth, and tumor

72 thermore, expression of BMP2 in vivo reaches maximal levels during the period of gliogenesis.

73 s showed high seroconversion rates, reaching maximal levels early in childhood, whereas others did no

74 otor unit activation pattern associated with maximal-level eccentric muscle actions.

75 D6) expression is cell cycle regulated, with maximal levels expressed in late S/G2 phases of the cell

76 roductive binding site for imidazole, with a maximal level for the rate constant of proton transfer n

77 used at microdialysis sites to raise SkBF to maximal levels for data normalization.

78 umor core and invasive rim regions, with the maximal levels found in the invading glioma cells locate

79 c was released into the cytoplasm only after maximal levels had been reached in the mitochondria, but

80 ial, Deltapsi, is maintained at a lower than maximal level (i.e., mild depolarization of mitochondria

81 essed at a low level in the Bvg+ phase, at a maximal level in the Bvg(i) phase, and at undetectable l

82 the early trophozoite stage and reaches its maximal level in the late trophozoite and schizont stage

83 helical gp41 trimers, increased rapidly to a maximal level in the primed state but decreased once sta

84 EIPIN3 have broader expression profiles with maximal levels in embryos and pollen, where LDs accumula

85 illate during the osteoblast cell cycle with maximal levels in G(1).

86 rogram . kg(-1) . min(-1)) increased LVEF to maximal levels in G(s)alpha x403 and G(s)alpha, whereas

87 levated levels of ID1 in NSCLC samples, with maximal levels in metastatic lung cancers.

88 5-hydroxymethylcytosine (5hmC) occurs at maximal levels in postmitotic neurons, where its accumul

89 AFB(1)-FAPY is detected at near maximal levels in rat DNA days to weeks after AFB(1) exp

90 is inactive in the duodenum and expressed at maximal levels in the distal small bowel.

91 ORA59 transcript levels do not reach maximal levels in the tga2 tga5 tga6 triple mutant, and

92 njection of 40 microg/mouse to 37-54% of the maximal level induced by a 1 microg/mouse injection of L

93 ence of all fibroblasts, although not to the maximal levels induced by fibroblasts.

94 We show that cell volume reaches the same maximal level irrespective of the osmolality of the medi

95 also regulated with the cell cycle, reaching maximal levels just before the onset of DNA synthesis.

96 els by cell adhesion, and remained at nearly maximal levels longer than wild-type activity.

97 ultivated oat), AV1, AV10 and Z1 mRNAs reach maximal levels midway through seed development but fall

98 ) with a similar time course and to the same maximal level observed in WT cells (85%).

99 , and its insulin responsiveness rose to the maximal levels observed in fully differentiated adipocyt

100 ells) on or before day 18 and increased to a maximal level of 2 ng/72 h by day 30.

101 T cells within 8 h of triggering, reaching a maximal level of 60% of control by 24 h.

102 erfusion further activated p38 MAPK, and the maximal level of activation (6.3-fold, P<0.01) was reach

103 At the maximal level of activation by GCAP, this isozyme alone

104 Amiodarone enhanced the maximal level of agonist-stimulated release of arachidon

105 only tyrosine 343 or tyrosine 464 supports a maximal level of AP-1 activation.

106 The maximal level of attenuation within normal lung was 18.5

107 However, the maximal level of bromodeoxyuridine incorporation is redu

108 abuse or dependence, current alcohol use, or maximal level of cannabis, sedative, stimulant, or cocai

109 This latter parameter is defined as the maximal level of cocaine at which the probability of sel

110 ensitivity, apparent affinity for RetGC, and maximal level of cyclase activation.

111 el of AHR resulted in a 50% reduction in the maximal level of CYP1A1 induced by 2,3,7,8-tetrachlorodi

112 while the trigeminal motor nucleus reached a maximal level of expression around P18.

113 Starting from a maximal level of expression at the time of adult emergen

114 s a unique pattern of expression, having its maximal level of expression in skeletal muscle.

115 activators working in concert to confer the maximal level of expression, but the mechanism of such s

116 ich removed hydrogen peroxide even after the maximal level of ferrylHb was reached.

117 oking were significant predictors of reduced maximal level of FEV(1) in males but not in females.

118 The maximal level of force development was dramatically decr

119 hins for 3 d was sufficient to establish the maximal level of functional synapses.

120 The maximal level of hHcsA expression was observed in late G

121 Maximal level of high-sensitive T troponins was 820 ng/L

122 The maximal level of IL-6, followed by CRP level, was highly

123 ties of Treg cells are required to achieve a maximal level of immune suppression.

124 eplication and subsequent establishment of a maximal level of latency.

125 centrations as low as 5 microM, and the half-maximal level of NarX autophosphorylation occurred at ap

126 The maximal level of NO produced by human macrophages was no

127 nding to Cdk2-cyclin E occurred at 12 h; the maximal level of p27 phosphorylation at Thr-187 in the t

128 ecreased the rate of phosphorylation and the maximal level of phosphoenzyme.

129 y increasing mouth air leak and reducing the maximal level of pressure that can be tolerated.

130 We now report that the maximal level of receptor-mediated second messenger sign

131 In at least some of the cases, the maximal level of sensitivity that was obtained could not

132 Pancreatitis reaches its maximal level of severity within 24 h of induction, and

133 ven repeated injections of toxin so that the maximal level of toxin was maintained for a sustained pe

134 The maximal level of TRPV5 current density stimulated by the

135 capacity as indicated by AS sensitivity and maximal level of vir-inducing activity at saturating AS

136 roduced in a luxS-dependent manner, reaching maximal levels of 2.5 muM in the late logarithmic growth

137 t increase of [3H]thymidine incorporation to maximal levels of 46.3 +/- 3.6% and 12.3 +/- 1.6% (P < 0

138 In contrast, the maximal levels of activated Stat1alpha produced by monov

139 transcription start site) was necessary for maximal levels of activity.

140 10 mg DBM in the in vitro model provided for maximal levels of ALP in cell extracts.

141 In this study, we confirm that the maximal levels of alpha-profibrin found over the course

142 to transform thrombin to its slow form, the maximal levels of alpha-profibrin rose to those expected

143 insc mRNA transcripts in neuroblasts confers maximal levels of apical Insc activity, which is require

144 vity in A375 anti-Fas-treated cells preceded maximal levels of apoptosis.

145 and for the ensuing activation, whereas the maximal levels of binding and activation attained at sat

146 Maximal levels of binding, activation, and apoptosis wer

147 In contrast, IL-4 knockout mice developed maximal levels of both mucosal and systemic immune prote

148 ppa B activation and Gal1-R expression, with maximal levels of both observed 3 days after gavage.

149 Maximal levels of CAF activity were not observed until 5

150 CAT virus infects a variety of tissues, with maximal levels of CAT gene expression found in the liver

151 HOECs secrete maximal levels of CCL20 at 6 h, following stimulation by

152 Maximal levels of circulating 25OHD were achieved in Vit

153 nstitutive response on transfection, whereas maximal levels of constitutive activity ranging from 30

154 al conditions of oligonucleotide uptake, the maximal levels of correct human beta-globin mRNA and hem

155 Viable S. aureus and Salmonella induced maximal levels of CSF mRNA expression and cytokine secre

156 Maximal levels of DAKAP200 are detected in the pupal pha

157 es grown in F-12K/serum medium revealed that maximal levels of DARP were detected on culture day 6 wi

158 In general, maximal levels of DNA scission (i.e. Cmax) varied over a

159 e levels that was temporally shifted so that maximal levels of dopamine were significantly higher and

160 inversely with Cmax values, indicating that maximal levels of etoposide-induced scission reflect the

161 ower buds is developmentally regulated, with maximal levels of expression coinciding with anthesis, w

162 We show that HS5-1 is required for maximal levels of expression from the Pcdh alpha1-12 and

163 odes a protein, Fat1p, which is required for maximal levels of fatty-acid import and has an acyl CoA

164 lantation as in the ex vivo experiment, with maximal levels of gene expression in endothelial cells o

165 t led to an increase in both the potency and maximal levels of gene expression induced by rapamycin,

166 Primary vaccine recipients had maximal levels of granulocyte-colony-stimulating factor

167 id transcription, while E74A is required for maximal levels of hid induction.

168 9 insect cells with recombinant baculovirus, maximal levels of Hsp72 protein were detected.

169 levels of IL-4 (<100 pg/ml) but much higher maximal levels of IFN-gamma than did Ag-specific B cells

170 Similar maximal levels of IL-22 transcripts could be induced in

171 moter (LSP) and the HSP1 promoters displayed maximal levels of in vitro transcription when TFAM was p

172 At maximal levels of induction it is one of the most abunda

173 increases to three out of the four sites at maximal levels of inhibition and quenching in phosphate

174 d peroxidation was observed rapidly and half-maximal levels of lipid peroxidation were reached at a 1

175 The maximal levels of lysis with Gag-, reverse transcriptase

176 a method that enables the prediction of the maximal levels of mRNA expression in Escherichia coli wi

177 r seconds initiated neuronal cell death, but maximal levels of neuronal cell death were observed with

178 dogenous miR-155 controlled the kinetics and maximal levels of PD-L1 induction upon IFN-gamma and TNF

179 load-recruitable stroke work failed to reach maximal levels of performance in GAMT-/- hearts (101+/-8

180 s time- and temperature-dependent, depresses maximal levels of pigment dispersion, and is therefore l

181 levels were increased by LPS at a time when maximal levels of plasma TNF-alpha were observed in both

182 the six genes that were studied resulted in maximal levels of PLF as quickly as 30 min following inf

183 pyrimidine (VU6005649), do exhibit different maximal levels of potentiation with L-AP4 versus glutama

184 Maximal levels of pro-B cell expansion, generally result

185 controlled asthma being associated with near-maximal levels of quality of life, with minimal impairme

186 are the first to demonstrate that less than maximal levels of receptor phosphorylation can block G p

187 ically discernible axial elements and SC and maximal levels of recombination.

188 1.5-cm) intrarenal cysts are scanned during maximal levels of renal parenchymal enhancement.

189 m region of about 50 bp that is required for maximal levels of replication.

190 Maximal levels of resistance correlate not with maximal

191 1 to the perinuclear region began only after maximal levels of RNA synthesis had been achieved, excep

192 min earlier in the cocaine-pretreated group (maximal levels of saline controls=378% increase, cocaine

193 rotecting group leads to the conclusion that maximal levels of screw-sense preference are induced by

194 These plasmablast responses preceded maximal levels of serum anti-S binding and neutralizing

195 The temporal regulation and maximal levels of SMI-32 and SMI-31 expressions on MF ta

196 al cell monolayers stimulated by thrombin to maximal levels of static sickle erythrocyte adherence al

197 rnative regulatory mechanisms are engaged at maximal levels of stimulation.

198 An unexpected finding was that even at maximal levels of TCR engagement and CD28-mediated costi

199 ncy of responding cells (particularly at sub-maximal levels of TCR engagement), and more prominently,

200 protein, and rates of CE formation, but not maximal levels of TGase protein.

201 urred slightly earlier than for IL-6 because maximal levels of TNF alpha were detected 2 to 3 days af

202 s from cellular systems, we demonstrate that maximal levels of transactivation in vitro require both

203 sidue at position 52 of CRP is inhibitory to maximal levels of transcription activation from Class II

204 Maximal levels of transcription was achieved when two PE

205 Maximal levels of transcriptional synergy between these

206 and oleate required either Fat1p or FATP for maximal levels of transport.

207 Nuclease protection assays showed maximal levels of TrkB and synapsin I mRNAs in the hippo

208 In neuronal channels, the maximal levels of uptake for W45A/S/F are about 50% thos

209 Maximal levels of VCL and VERL were found in February 20

210 Maximal levels of Xbra expression are attained using low

211 tutive activation of medium and low, but not maximal, levels of Hh target gene expression.

212 s were detected during infection, reaching a maximal level on day 3.

213 d by progesterone in pregnant mice, reaching maximal levels on day 12.5 of pregnancy.

214 The SMM concentration reached maximal levels on day 2 of the post-treatment period for

215 TMP reached maximal levels on day 3 after drug administration for do

216 All of these UPR events reach maximal levels once Ig synthesis and secretion are marke

217 e activity increased more slowly and reached maximal levels only after 20 h of exposure, leading to a

218 3 to sensitized rats restored phospho-ERK to maximal levels only in MPC when examined 7 d later.

219 employed increases basal p70 activity to the maximal level otherwise attained in the presence of insu

220 The maximal level released was about 0.105 mg/dm(2), which i

221 els required >24-h incubation, that reaching maximal levels required at least 18 h of cytokine treatm

222 s their concentration to 7% and 10% of their maximal level, respectively, strongly suggesting that de

223 the presence of either Mn(2+) or Mg(2+) with maximal levels seen with 10-20 mM Mn(2+).

224 ge-rich lesions increased faster and reached maximal levels several fold higher than in the macrophag

225 At their maximal levels, state practice prerogatives authorized a

226 be and insufflated the colon with air to the maximal level that the patient could tolerate.

227 bFGF stimulated DNA synthesis to the same maximal level under both conditions, but chlorate-treate

228 sustained an isometric elbow flexion at 30% maximal level until exhaustion while their brain (EEG) a

229 Binding was near maximal levels up to 1.6 kb away from parS, and signific

230 ificant lag before mRNA levels increased; 2) maximal levels were not reached until 48-72 h after the

231 odest when DROJ1 was depleted alone, reached maximal levels when DROJ1 and HSP70/HSC70, or DROJ1 and

232 mes; the mass of NGF decreased to 10% of the maximal level within 2-3 mm of the polymer matrix.

233 ulin M (IgM) and IgG were produced to almost maximal levels within 1 week of a single immunization.

234 pupal commitment on day 3 and is induced to maximal levels within 12h by low levels of 20-hydroxyecd

235 e smooth muscle-like cells (BC3H1), reaching maximal levels within 3 to 4 min.

236 e cells) or with thymine dimers increased to maximal levels within 30 min after UVB.

237 Some genes are expressed at near-maximal levels within 30 min, whereas others show no sub

238 within 10 minutes of stimulation and reached maximal levels within 60 minutes.