ライフサイエンスコーパス: maximum response

1 wo of which are ongoing and have not reached maximum response.

2 cularly sensitivity to GABA blockade for the maximum response.

3 ween 1.5 and 3 pi radians at the location of maximum response.

4 important component of treatment to achieve maximum response.

5 units exhibited a steeper slope and a higher maximum response.

6 tion of acetylcholine that produces half the maximum response.

7 tegorized into four classes based upon their maximum responses.

8 n-response curves with reduced but plateaued maximum responses.

9 dant manner (effector concentration for half-maximum response=1.2 mM+/-0.7).

10 ce of Ca2+, phosphatidylserine, and diolein (maximum response, 360 +/- 4% versus 342 +/- 9% of contro

11 ty = 5.7 microg/mL), and 58 (AC(50) = 38 nM, maximum response = 82%; solubility = 51.2 microg/mL).

12 bility = 7.3 microg/mL), 56 (AC(50) = 99 nM, maximum response = 84%; solubility = 5.7 microg/mL), and

13 probes of PKM2 including 55 (AC(50) = 43 nM, maximum response = 84%; solubility = 7.3 microg/mL), 56

14 The mean maximum response after 4 mg/kg MK-801 was 13+/-2%.

15 haelis-Menten equation to derive R(max), the maximum response amplitude, and sigma, the contrast nece

16 stitutions at Tyr217 substantially decreased maximum response and increased the EC50 for carbachol, d

17 Cone R(max) (maximum response) and cone S (sensitivity) parameters we

18 transduction to obtain values for log Rmax (maximum response) and log S (sensitivity).

19 (50) (the concentration that produces a half-maximum response), and the Hill coefficient (the maximum

20 .41 at 0 minutes, 0.37 at 1 minute, 0.42 for maximum response, and 0.39 for the area under the curve

21 gh expression of TRH receptor alone produces maximum responses approximately 48 h after injection, co

22 < 0.01; DNA, 28.4% increase, p < 0.001; HP, maximum response at 0.5 h, 50% increase, p < 0.001).

23 old increase in pro-TRH biosynthesis, with a maximum response at 10 nm.

24 ng in a concentration-dependent manner, with maximum response at 20 to 25 min.

25 nse was dose-dependent (EC50 = 25 nM) with a maximum response at 300 nM and a minimal observable resp

26 sensor response to NO reduction indicated a maximum response at pH 3.

27 The prepared enzyme electrodes exhibited maximum response at pH 7.0 and 45 degrees C +0.35 V and

28 mulation changed over the cycle, with larger maximum responses at both proestrus and estrus relative

29 ll changes in the ocean's O(2) content, with maximum responses at suboxic concentrations where anaero

30 lclozapine displayed substantially increased maximum responses at the Y106A and W101A mutants, slight

31 employed to optimize the conditions for the maximum response based on 54 different experiments.

32 hich choline is actually a full agonist, its maximum response being limited only by channel block.

33 NKCC2A-/- compared with wild-type mice, with maximum responses being significantly diminished.

34 Therefore, traditional features depending on maximum response change will cause confusion during furt

35 It exhibited a maximum response current to histamine at applied potenti

36 motherapy is at least 4 to 6 months or until maximum response, depending on toxicity and in the absen

37 headings approximately perpendicular to the maximum response direction.

38 concentration required to produce 50% of the maximum response [EC(50)], 0.52+/-0.07 micromol/L) and e

39 y the empirical CRC parameters efficacy (the maximum response), EC(50) (the concentration that produc

40 a non-competitive mechanism that reduced the maximum response elicited by GABA.

41 compound model also explain why the reduced maximum response elicited by some partial agonists can b

42 ulatory effect of ACh was 0.15 microM with a maximum response equal to 67% of that obtained by a maxi

43 t bind to receptors but produce only a small maximum response even at concentrations where all recept

44 ric 5-HT3ARs (64 +/- 7% and 80 +/- 4% of the maximum response evoked by the endogenous orthosteric ag

45 intensity function types and their slope and maximum responses, for units with characteristic frequen

46 ET-1 in all (n = 12) C-units, with mean and maximum response frequencies of 0.08 +/- 0.02 and 1.5 +/

47 ET-1 was 3.16 +/- 0.31 min, and the mean and maximum response frequency were 2.02 +/- 0.48 impulses (

48 concentration of ligand that elicited 50% of maximum response in (86)Rb flux assays (K1/2), also refe

49 A maximum response is observed for 4.8-nm-thick PNS, with

50 ts in primary hepatocytes (20-fold), and the maximum response is obtained at a glucose concentration

51 A maximum response is produced at a dose of 4 micrograms/k

52 CB response showed a size-dependent shift in maximum response level from 2 microg/ml of 5 nm sized NP

53 The video's green channel (maximum response near 540 nm) shows the color change due

54 a dose- and time-dependent manner, with the maximum response observed 30 min after MTII injection.

55 ase of 3-4-fold in media VEGF levels, with a maximum response occurring at a concentration of 10 nM.

56 thin 6 h, with 1 mg/kg tamoxifen producing a maximum response of 15-20-fold.

57 T-based Ca(2+) flux assay, we found that the maximum response of alpha4beta2 receptors to agonist was

58 Moreover, a selective reduction in the maximum response of the high-affinity component was appa

59 The maximum response of the retinogeniculate synapses, conve

60 f the receptor to between 55 and 110% of the maximum response of the wild-type receptor to the agonis

61 We found that experience increased maximum responses of putative excitatory neurons but had

62 atory neurons but had the opposite effect on maximum responses of putative inhibitory neurons, an obs

63 Examination of the efficacies (maximum responses) of the various cytokines showed that

64 on the stimulus strength required for a half-maximum response, of the M-cone population was 38-fold l

65 Treatment was repeated every 28 days until maximum response or a maximum of 6 cycles.

66 ate and subsequently allowing the asymptotic maximum response probability to be a free parameter.

67 3 locations </= 15 dB, the fitted asymptotic maximum response probability was <80%, consistent with t

68 dB because of a reduction in the asymptotic maximum response probability.

69 ated a decrease in the apparent k(m) and the maximum response, R(max), suggesting a decrease in the n

70 aseline (non-drug) training, the time of the maximum response rate (peak time) for mature rats was ap

71 The maximum response rate (Rmax) and the reinforcement rate

72 mely the number of molecules per site n, the maximum response RM and the concentration at half satura

73 n the EC50 of carbachol and decreases in the maximum response (Rmax).

74 n at frequencies between 1 and 60 Hz, with a maximum response seen at 20 Hz.

75 h respect to the periphery, the time to half-maximum response (t1/2a) for arterial insulin was the sa

76 th 10-fold higher affinity and 3-fold higher maximum response than murine FXR-LBD.

77 The time to maximum response, the gallbladder ejection fraction, and

78 ression coefficient, R(2)=0.9912), while the maximum response time for each measurement was less than

79 initiation was individualized to begin after maximum response to AD as assessed by monthly digital re

80 tiation of RT individualized on the basis of maximum response to AD, achieves disease control rates c

81 pretreatment (10 microM, 48 hr) reduced the maximum response to agonist-stimulated [3H]inositol phos

82 The maximum response to alphabeta-MeATP was 36 +/- 23 % (ran

83 dependence also did not shift sensitivity or maximum response to baclofen in CA1 neurons.

84 nt gained 8-fold affinity and more than 250% maximum response to CDCA in vitro.

85 nd morphine activated GIRK currents, but the maximum response to DAMGO was greater than that of morph

86 The maximum response to glycine also appeared much reduced,

87 is defect corresponded to a reduction in the maximum response to insulin.

88 The maximum response to PbTx-1 was approximately two-fold gr

89 In untreated neurons, maximum responses to GABA and the apparent GABA EC50 inc

90 periments at two latitudes demonstrates that maximum responses to warming are concentrated in late wi

91 ng that a decrease occurred in the BRI1 half-maximum response values.

92 min), and the concentration of FMLP for half-maximum response was 28.6 nM.

93 The mean maximum response was 39+/-4% at 20 Hz.

94 lthough with graded dobutamine infusion, the maximum response was not different from that in controls

95 script, the screening time was very fast and maximum response was obtained up to 11-fold higher than

96 mm rostral to the calamus scriptorius (CS); maximum responses were elicited from a site 0.6 mm rostr

97 ive than wild-type control rods and that the maximum responses were much smaller in amplitude.

98 Maximum responses were observed when the radiation beam

99 The maximum response with 82% lysis of labeled target cells

100 d a substantial pH-dependent decrease in the maximum response with a pK(a) near 6.0.

101 At 20 and 25 mg/kg/day R-FB, we obtained the maximum response with up to 90% inhibition of total tumo

102 nt manner showing an age-related increase in maximum response without change in EC50 or slope value.