ライフサイエンスコーパス: may

1 administration of 5-FU followed by GDC-0941 may suppress disease relapse after 5-FU-based gastric ca

2 uced conformational switching of benenodin-1 may also be relevant to the biological function of these

3 egranulation by PgLPS1690 and PgLPS1435/1449 may contribute to the modulation of disease progression.

4 of nonconserved residues (Ser/Thr(296/297)) may perturb the local fold.

5 athepsin S-mediated activation of IL-36gamma may be important in the development of numerous IL-36gam

6 s that miR-203-3p, miR-664-3p and miR-708-5p may be implicated in pathways determining lifespan in ma

7 Milky Way, known as Sagittarius A* (Sgr A*), may have affected the habitability of Earth-like planets

8 ect pediatric liver mechanical abnormalities may not allow detection of mild disease and may lead to

9 ith increased sedimentation this acclimation may support further transitions to sponge dominated reef

10 Mps, indicating that Ep3 receptor activation may be a promising therapeutic target for acute MI.

11 Elderly adults may master challenging cognitive demands by additionally

12 ly to middle age and a low BMI in middle age may be positively associated with ALS risk.

13 of how our biological clocks change with age may create valuable opportunities to improve health and

14 understanding of pathogenic pathways in AKI may identify novel therapeutic approaches.

15 play between membrane and CaM binding to Akt may help in the development of potential targets to cont

16 ospholipid transporter activity of ALA1/ALA2 may be necessary for the formation of similar invaginati

17 euroactive steroids such as allopregnanolone may be potential therapeutic targets for depression and

18 rediction of El Nino/La Nina events and also may be applied in the investigation of other climate var

19 The dataset also may be incomplete in TBI death recording or contain misc

20 nergic control of CRF levels in the amygdala may contribute to the transition from moderate to compul

21 The amygdala may, therefore, play a central role in RL.

22 regular approaches for QTL mapping analysis may be adopted for metabolites-phenotypes association an

23 bility to regulate complement activation and may benefit more from complement-inhibiting therapy than

24 te cartilage beyond mere static analysis and may provide the basis for more refined graduation strate

25 age of interstitial fluid from the brain and may reflect underlying cerebral small vessel disease (SV

26 er a direct role for RANK in lung cancer and may explain why female sex hormones accelerate lung canc

27 ses and microbial community composition, and may have significant implications for CO2 losses from tr

28 eoretical basis for tumor growth control and may also find utility in therapeutic planning to avoid p

29 al by suppressing endogenous DNA damage, and may control cell fate through the regulation of CHK1.

30 may not allow detection of mild disease and may lead to underestimation of severity.

31 multiple aspects of autoimmune disorders and may play a role in triggering disease.

32 he retinal vasculature is easily imaged, and may be a surrogate biomarker of cerebral and systemic va

33 llows for larger prosthesis implantation and may be an important adjunct to surgical AVR in the trans

34 ents co-exist within a single individual and may explain in part the heterogeneous fates of metastati

35 e specifically in visual decision making and may support sensory aspects of the decision, such as int

36 ght on the particle formation mechanisms and may lead to better-controlled synthesis protocols.

37 e regulation during axonal morphogenesis and may shed light on MAP7 function in neurological disorder

38 er of diseases affecting striated muscle and may also be a schizophrenia risk gene.

39 ne-related hybrid material, is truly new and may have broad interest in combination of experimental a

40 plays a key role in attention orienting and may contribute to the hypervigilance that is a common sy

41 biome is indicative of clinical outcomes and may be a valuable guide for personalized management and

42 cross-over occurs in animal populations and may have important fitness consequences.

43 with target proteases or other proteins and may play an important role in the various beneficial fun

44 evolutionary rate of the outbreak strain and may have increased its adaptability, as many mutations i

45 severe testis dysgenesis in DBP-MPW animals may result from the presence of basally migrating GC and

46 These results suggest that CDK6 antagonists may be a promising therapeutic approach for Hh-associate

47 development and suggest that PXR antagonists may provide a new approach for ALD therapy.

48 entified, the (1)H NMR chemometrics approach may contribute in the choice of the temperature and time

49 This approach may be amenable to numerous enzymes and to engineering a

50 with prunasin, tyramine and beta-p-arbutin, may be limited in food applications.

51 tribution of cropland to more suitable areas may improve sustainability and reduce pressure on water

52 sly believed suggesting that this arrhythmia may have a genetic component.

53 While rugged and robust assays may be easily developed for certain enzymes, HTS assays

54 ing depression, rather observed associations may reflect residual confounding relating to characteris

55 Variations in attrition may be explained by program director attitudes, although

56 otubule-binding domain, and RhoA-GTP binding may relieve this inhibition during mitosis.

57 n between B. pertussis and B. bronchiseptica may result from selective adaptation of B. pertussis to

58 ral replicative capacity of subtypes A and C may paradoxically contribute to their more efficient spr

59 This distinctive capacity may emerge from an ability, shared with other animals, t

60 Somatic mutations such as CARD11 may have an impact on response to ibrutinib, may inform

61 n for the diagnosis, and although some cases may respond initially to therapy, there is a high incide

62 the hypothesis that SOD delivery to caveolae may specifically inhibit this pathological pathway, we c

63 ossibility that the bioactivity of such CECs may be effectively preserved through direct conjugation,

64 , it is possible that collagen-binding cells may change their phenotypic traits.

65 ed peptide (CGRP), we hypothesized that CGRP may provide a molecular identifier of the CO2 arousal ci

66 n processing-suggesting that similar changes may critically, and more broadly, underlie the neural co

67 Clinicians may help protect patients after discharge by serving as

68 biological pathways through which clozapine may act to cause this serious adverse effect.

69 t disappeared, and that visual communication may have replaced auditory in these colourful, diurnal f

70 Prevention of cardiovascular complications may be accomplished through a sound understanding of the

71 nderstand how these noncardiac complications may affect the long-term outcome in these patients and w

72 amygdala-prefrontal functional connectivity may be associated with severity of suicidal ideation and

73 ed procedures, hospital market consolidation may represent the best value proposition: better quality

74 rket in 2015, but its use in other countries may continue.

75 of examining whether carbon disulfide (CS2) may play a role as an endogenously generated bioregulato

76 ing of a signaling pathway such as NG2/CSPG4 may have different effects on cell behavior with tumor p

77 logical evidence of CTE, suggesting that CTE may be related to prior participation in football.

78 We demonstrate that the Co(III)2(IV)2 cubane may be electrochemically generated and the electronic pr

79 ained constant, suggesting that ETO-curcumin may provide superior anti-inflammatory efficacy compared

80 , suggests that the microtubule cytoskeleton may facilitate access of IRS-2 to downstream effectors s

81 anisms with a similar sensitive cytoskeleton may be susceptible to environmental changes.

82 n led us to speculate as to whether our data may form the basis for a free radical substituent consta

83 ndergoing surgery, competing causes of death may diminish the benefit, and there is no evidence to re

84 ddition, we have demonstrated that DeBooster may provide new insights into understanding the regulato

85 N protein expression and BCR surface density may influence clinical response to therapeutic inhibitio

86 se cell therapy investigational trial design may be informed by new anatomic and perfusion insights.

87 DIET may also have a role in anaerobic methane oxidation coup

88 Such differences may have clinical significance, as therapeutic targeting

89 Such differences may ultimately contribute to their unique behavioral pro

90 These differences may extend to differences in cognition among individuals

91 he prevalence of pediatric and adult disease may be similar.

92 on of interstrand cross-links in genomic DNA may contribute to aging, neurodegeneration, and cancer.

93 teins with human anelloviruses, and PCV2 DNA may be present in human food and vaccines.

94 n association with avidity index and DNAemia may help to assess the risk of HCMV fetal transmission.

95 form states, driven, nonequilibrium dynamics may.

96 downregulation of HLA-E by high-risk HPV E7 may contribute to virus-induced immune evasion during HP

97 These cumulative effects may result in downstream phenotypic consequences in sude

98 g climatic and temporal variations, how ENMs may be released into the environment, and the effect of

99 determines the nature and strength of eQTLs may help identify cell types relevant to pathophysiology

100 sity risk, while emotional undereating (EUE) may be protective.

101 es-dependent regulation of PlexA1 expression may have been crucial in the evolution of mammalian CS s

102 nterpreted here as decreased SST expression, may disrupt responses to fear and anxiety regulation in

103 es or anything about how those compound eyes may have functioned.

104 ur and what genetic or environmental factors may hinder it.

105 Other factors may need to be considered in deciding the optimal approa

106 ndependent of, or explained by, risk factors may provide etiological insight.

107 the notion that patients and their families may not need or want palliative care involvement early i

108 tion and incontinence where sensory feedback may engage these reflexes inappropriately.

109 t, these results suggest that NASH FibroSure may be used, especially among female patients, to help m

110 These findings may be relevant to the aetiology and treatment of divers

111 ring periods of inflammation, these findings may have important implications to understanding the beh

112 , preliminary evidence suggests that flicker may also entrain endogenous brain oscillations, thereby

113 ull and release approach to graphene folding may find applications in the theoretical studies and fab

114 However, although field potentials (FPs) may reflect the synaptic currents of neurons near the re

115 teopenia as indicators of underlying frailty may provide complementary prognostic information on long

116 the risk of low birthweight (LBW; <2,500 g) may depend upon maternal nutritional status.

117 propose that co-option of single-copy genes may be a common but relatively understudied mechanism of

118 f factors, including age, sex, and genotype, may affect these metabolic processes.

119 sulfide oxidation as a result of glaciation may act as a source of CO2 to the atmosphere.

120 ive exclusion of molecules needed for growth may contribute to regeneration decline.

121 s indicate that S. pulchra in mesic habitats may respond positively to a wider range of temperature i

122 uch as sowing date and successive harvesting may be useful tools towards the production of high quali

123 Assessing liver health may be important for reducing the risk of future CHF eve

124 The results and methodology reported here may be used to improve the understanding and prediction

125 ssue-wide gene expression, as observed here, may underpin a profound immune dysregulation, setting th

126 ncer genetic testing based on family history may miss clinically actionable genetic changes with esta

127 Robustness of function through homeostasis may be ensured in any system through mechanisms similar

128 where SNs were resected, remaining hotspots may have been caused by residual lymphatic flow after re

129 lity neighborhoods and low-income households may experience greater HPA and HPG activity, leading to

130 Our results suggest that HRV may serve as an easily acquired, noninvasive, and low-co

131 e facts, it is concluded that flaxseed hulls may be a beneficial food additive.

132 study suggests that the lateral hypothalamus may also participate in the formation and storage of mem

133 start bronchoscopy following hypoventilation may decrease hypoxemia without compromising patient tole

134 may have an impact on response to ibrutinib, may inform clinical decisions, and should be evaluated i

135 changes of molecular events in AM but not IM may be an important factor in the reduction of cancer in

136 Early anatomic imaging may show that a tumor has increased in size, but this co

137 e initially formed 5-alkenyl iminohydantoins may be hydrolyzed and oxidatively deprotected to yield h

138 hich gluatamatergic signalling is implicated may be caused by aberrant salience leading to a change i

139 rk suggests that the inverse-trans-influence may occur beyond high oxidation state 5f metals and henc

140 This interaction may represent a therapeutic target in cancers that expre

141 onies that engage in more brood interactions may have had more resources available to cope with two p

142 esults reveal that light-based interventions may be therapeutically effective in improving sleep regu

143 ure school-based environmental interventions may be beneficial for this important public health probl

144 neity of malaria suggests that interventions may be targeted for maximum impact.

145 It may be possible to extract objective data from a patient

146 such as P. pastoris and C. albicans, and it may have novel moonlighting functions in the nucleus.

147 Furthermore, it may be speculated that this pair of side chains could pr

148 licated in neuronal pathologies, in which it may influence neuronal survival.

149 ge in the immunocompromised host, in whom it may be asymptomatic or present as chronic diarrhea.

150 phase of their autumn transatlantic journey may be diminished.

151 limpse of what an active TAM receptor kinase may look like and suggesting a potential role for the ju

152 ent of PLINs and their distribution with LDs may be linked to the diverse lipid storage in muscle bet

153 ein counteracting oxidative promoter lesions may modulate gene expression.

154 Measurement of lactate levels may have utility in early risk stratification of pediatr

155 ch suggests that urinary testosterone levels may not accurately reflect blood levels during mini-pube

156 Our findings suggest that lithium may reduce melanoma risk and associated mortality.

157 nerations of programmable molecular machines may have significant roles in chemical synthesis and mol

158 use of 2D membrane based off surface matrix may present the new platform to sensitively measure biom

159 ed in this study suggest that this mechanism may be useful in applications across various fields.

160 Involved mechanisms may be correlated to restoration of ERK and AKT signalin

161 tors are abundant, antipsychotic medications may affect neural function in studies of animals, health

162 This method may also prove useful for imaging other structures, such

163 suggest that differences in DNA methylation may partly explain the enantioselectivity of fipronil to

164 proteins and a related order of gut microbes may provide a link between mucosal and joint immunity in

165 Furthermore, this model may facilitate the identification of APOL1-interacting m

166 ibility that HMBA or related small molecules may be explored as therapeutic adjuvants to improve dise

167 ed by metabolic challenge, amoeboid movement may thus constitute a common endpoint of both EMT-depend

168 a; however, ubiquitous deleterious mutations may severely decrease its fitness.

169 bined approach targeting HDAC1/HDAC2 and MYC may present a novel and molecularly defined strategy to

170 However, each node in a network may be associated with many attributes.

171 that developmentally defined sets of neurons may differentially participate in hedonic aspects of sen

172 ing that natural variation in repeat numbers may optimize the chance for survival.

173 cept that targeting thrombin or fibrin(ogen) may limit pathologies in obese patients.

174 BF2/OIT may provide an additional OIT option for patients with c

175 s of opinion regarding whether there may, or may not, have been protective efficacy in the RV144 vacc

176 cis-regulatory elements in diploid organisms may cause allele specific expression (ASE) - unequal exp

177 Parabens may be added to cosmetic and personal care products for

178 e substitutions in C. elegans, which in part may be due to different methodological approaches, inclu

179 that overgeneralization in anxiety patients may be mediated by an inability to recruit the dlPFC, wh

180 interstitial tissue, confirmed in patients, may have important implications for biotherapies such as

181 The specific fatty acid pattern may be influenced by metabolic, genetic, and dietary fac

182 Floral temperature patterns may therefore represent a new floral cue that could assi

183 provide novel explanations regarding how pH may drive cellular processes; how plants may respond to,

184 pH may drive cellular processes; how plants may respond to, and perhaps sense stresses; and how orga

185 n Africa during the Pliocene and Pleistocene may have been decoupled from aridity.

186 Use of this end point may expedite therapeutic development with the intent of

187 These polymorphisms may be critical for the development of specialized plant

188 his study reveals that raspberry polyphenols may present a dietary route to the retardation or amelio

189 a diverse immunocompetent patient population may provide a foundation from which to make informed dru

190 ions and indicates that marine top predators may be more sensitive to the rate of ocean warming rathe

191 evolution, and its inherent predictability, may occur and what genetic or environmental factors may

192 r moderate to severe OSA; current prevalence may be higher, given the increasing prevalence of obesit

193 nd orbital convergence in ancestral primates may have helped them to efficiently discriminate, target

194 k and, therefore, an open surgical procedure may not be feasible or appropriate.

195 Several of these processes may be potential therapeutic targets for the prevention

196 ons in humans, understanding these processes may improve clinical management and public health diseas

197 Recent data suggest that some L1 protein may accompany the viral genome beyond the endosomal comp

198 Targeting ADCC-Abs to internal proteins may be a potential mechanism of universal vaccine design

199 esearch has indicated that secreted proteins may play a major role.

200 These findings suggest that PVP may be useful in the standard bedside clinical assessmen

201 , thermal drying, incineration and pyrolysis may decrease NH3 (9-11%) and GHG (11-18%) emissions; nit

202 indings suggest that SIRS criteria and qSOFA may have limited utility for predicting mortality in an

203 eriencing renewed excitement that mutant RAS may finally be conquered.

204 ned elusive, prompting a perception that RAS may be undruggable.

205 The use of RBV may not be necessary to achieve SVR in this patient popu

206 Such Mn(II)-phyllomanganate reactions may thus alter metal uptake by blocking key reactive sit

207 fferent immunoassays and visual PET readings may influence the use of CSF biomarkers and/or amyloid P

208 onclude that targeted alpha-therapy regimens may stretch beyond the realm of micrometastatic disease

209 nt 26-32 region, suggesting that this region may play a regulatory role.

210 This region may underlie our ability to understand the structure of

211 attenuation among reward-processing regions may be a particularly powerful endophenotypic predictor

212 PTEN down-regulation may promote beta-oxidation through beta-catenin, whereas

213 These epigenetic regulators may act to facilitate the expression and/or repression o

214 from this structure-reactivity relationship may aid in the development of new highly efficient photo

215 Targeting PARP-associated DNA repair may represent a novel therapeutic strategy for gliomas.

216 at replacement of colonized water reservoirs may be required for long-term clearance.

217 st that increased cerebrovascular resistance may represent a previously unrecognized contributor to A

218 enses and responds to stress; such responses may be modulated by MisRS (NGO0177 and NGO0176), a two-c

219 The results may help in understanding the origin of interface instab

220 raction between RNA polymerase and ribosomes may contribute to the coupling of transcription to trans

221 hods to populations with the increased risk, may reduce the observed disparities for digestive cancer

222 blematic, since prior immunity to a scaffold may inhibit immune responses to the antigen-scaffold com

223 alled PRES (Personalized REgimen Selection), may significantly increase response rates for breast can

224 Our data suggest that SERPINA3 may be involved in the pathogenesis and the progression

225 beta signalling and enhances ERK5 signalling may be useful to counteract endothelial dysfunction.

226 on, acupuncture at local versus distal sites may improve median nerve function at the wrist by somato

227 n from direct harmful UV rays; however, skin may still remain exposed to reflected and indirect UV ra

228 Functional studies revealed that SLC25A46 may play an important role in mitochondrial dynamics by

229 SNF may play a role in both by supplying N to leaf tissues f

230 ng additional data on foliar P, but doing so may increase the capability of models to predict future

231 g NF-kappaB activity, suggesting that SP110b may serve as a potential target for host-directed therap

232 synaptic activity in APP mice; and that SS31 may confer protective effects against mitochondrial and

233 properties of this unique high-valent state may be probed by in situ spectroscopy.

234 gen availability, the dominant leaf strategy may be either deciduous or evergreen depending on the in

235 This strategy may be a valid alternative to routine full-course antibi

236 This strategy may enable the parasite to balance the benefits of the e

237 Such form of cross-over of stress may be beneficial if it enhances adaptive responses to e

238 multiple brain areas, but that the striatum may have a privileged role in timing because it has a mo

239 conformational restriction of the substrate may play a role in catalysis.

240 the Thr(567) in the MT1-MMP cytoplasmic tail may function as a regulatory mechanism to impact ovarian

241 ipants with previous or current pulmonary TB may have the potential for causing harmful postvaccinati

242 Interactions between recruited APC and TC may occur as an early event promoting allergic airway in

243 ative ease of use and abundant access to tCS may represent a broad-reaching and important advance for

244 ers, but not with TGIF, suggesting that TGIF may have an independent input into HOXA1-bound regions.

245 commended techniques cover alternatives that may suit various biological goals, experimental designs,

246 a significant reservoir of tumor cells that may acquire or exhibit resistance.

247 linear behavior across force conditions that may be exploited at a systems level by combining slow an

248 not take into account free energy costs that may be associated with structural rearrangements between

249 GFR, followed by an age-related decline that may be more rapid in related donors.

250 systems is often a collaborative effort that may be detrimental to the producers.

251 phenotypic complexity and evolvability that may have implications for biological evolution.

252 is framework reveals chromatin features that may be predictive of clinical response to epigenetic the

253 In addition, avenues are identified that may be exploited for photosynthesis engineering projects

254 hus favoring infection and inflammation that may eventually lead to tissue remodeling and respiratory

255 e Americans and potential interventions that may ultimately prevent myopia-related disease.

256 functional and anatomical organization that may underlie intrinsic auditory regionalization.SIGNIFIC

257 ad3 has contrasting functional outcomes that may involve activation of an integrin/reactive oxygen ax

258 radiation and identify target pathways that may be exploited for neoadjuvant therapies.

259 ctions among a diverse set of processes that may vary temporally, limiting their potential to predict

260 etic parameters, such as stirring rate, that may be exploited to design other quasicrystal-forming se

261 ruct is a first-of-its kind theranostic that may serve as a new approach in our growing therapeutic t

262 ow background in many important tissues that may be sites of infection such as the lungs and soft tis

263 y was found to be a crucial uncertainty that may have a substantial influence on the life-cycle impac

264 of potential cell/circuit underpinnings that may underlie cognitive impairments in offspring of mothe

265 not improve outcomes overall, although there may have been some effect among Fusarium ulcers.

266 fferences of opinion regarding whether there may, or may not, have been protective efficacy in the RV

267 drug treatment is unsupervised and therefore may be suboptimal, is less well characterised.

268 re collagen fragments, suggesting that these may be causally related to the observed accumulation of

269 injuries even within the mild range as they may interact with genetic risk to produce negative long-

270 Once the Sn+1 particles are formed, they may further nucleate to form larger polysulfur aerosols,

271 This may be a significant contributor to excessive inflammati

272 m of analysis and the implications that this may have for bioinformatics database design.

273 demotivating in some contexts and that this may occur through an attention-based mechanism.

274 The tool may allow for estimation of circulatory risk and improve

275 ns from phosphate homeostasis (PHO) to TORC1 may differ between C. albicans and S. cerevisiae The con

276 Instead, referral for heart transplantation may offer their best chance at long-term survival.

277 eates large coherency strains, which in turn may promote crack initiation under load.

278 d and Wnt-SFRP interactions, which, in turn, may reveal further Wnt signaling pathways.

279 states, rather than specific receptor types, may be a viable strategy for future drug development.SIG

280 gest that an effective VAR2CSA-based vaccine may require multivalent activity.

281 VSVDeltaG pseudovirion vaccines may prove as efficacious and have better safety, but the

282 These FYCO1 variants may impair autophagic function, leading to RV formation

283 thesized that certain PCSK9 genetic variants may modify the association between LC n-3 PUFA intake an

284 By harnessing multiomics approaches, we may gain valuable insights into their potential function

285 angiogenic responses through TGF-beta, which may act as the bridging molecule that mediates IL-37 bin

286 hylxanthines theobromine and caffeine, which may also affect vascular function.

287 the loss of starburst amacrine cells, which may be an important target in the mechanism of complex 1

288 sition between the two configurations, which may give rise to disease-associated repeat expansion.

289 e N2O accumulation in denitrification, which may contribute to further design strategies to control g

290 imaging marker of Parkinson's disease, which may be used in clinical trials of disease-modifying ther

291 der to influence experimental efforts, which may in turn influence the outcome of cellular differenti

292 ression and this negativity: a finding which may also be relevant for clinical imaging of other hemat

293 rates sparse and orthogonal AP firing, which may support sparse coding during hippocampal information

294 ulation of central metabolic pathways, which may identify potential therapeutic targets for the disea

295 nce, an anatomic substrate is present, which may enhance the occurrence of EBW during atrial fibrilla

296 stretches of phosphorylated residues, which may be a means to amplify signals or stabilize a particu

297 dates the prognostic power of RETREAT, which may help standardize post-LT surveillance, provide a fra

298 product, particularly in these patients who may have renal insufficiency.

299 These data suggest that zinc may inhibit cell proliferation of esophageal cancer cell

300 Thus, ZVI may be used to increase biocathode CH4 production, assis