ライフサイエンスコーパス: meaningful

1 s long as both are specific and biologically meaningful.

2 energetic definition of intermediates is not meaningful.

3 se II (Pol II) transcription or biologically meaningful.

4 erences were small and may not be clinically meaningful.

5 ned to represent biologically and clinically meaningful abstractions of cancer gene expression data.

6 nal survival estimates provide an important, meaningful addition when discussing prognosis with patie

7 iceptors and their activation there produces meaningful analgesia.

8 Such rearrangements preclude a meaningful analysis of the experimental spectrum.

9 tomic classification identifies biologically meaningful anatomic phenotypes and provides a replicable

10 global optimization of Link Surprise yields meaningful and more accurate link community structures t

11 ose Measures of response that are clinically meaningful and occur early are an unmet need in metastat

12 neurons, is hindered by the lack of suitable meaningful and reproducible methodologies.

13 To ensure meaningful and reproducible quantification of in vitro d

14 ate treatment was associated with clinically meaningful and statistically significant improvement com

15 ess diseased segments resulted in clinically meaningful and statistically significant improvements in

16 partial response also experienced clinically meaningful and statistically significant improvements in

17 onclusion Pembrolizumab exhibited clinically meaningful antitumor activity and an acceptable safety p

18 nib represents a new therapy with clinically meaningful antitumour activity and a manageable safety p

19 s well tolerated and demonstrated clinically meaningful antitumour activity in recurrent or metastati

20 fect on postoperative patient outcomes using meaningful assessment instruments and reliable processes

21 o rank signature-projection pairings so that meaningful associations can be quickly identified.

22 k for the discovery of stable and clinically meaningful asthma subtypes.

23 tween groups were significant and clinically meaningful at weeks 9 and 15 in favour of nivolumab for

24 atory experiences show distinct responses to meaningful auditory stimuli.

25 the proportion of Zwisch ratings indicating meaningful autonomy ("Passive Help" or "Supervision Only

26 study aims to validate and apply clinically meaningful bands to the ItchyQuant, an illustrated self-

27 The set of clinically meaningful bands with the highest weighted kappa coeffic

28 This achievement is scientifically meaningful because developing textile MFCs requires inte

29 ollateral ventilation resulted in clinically meaningful benefits in lung function, dyspnea, exercise

30 lower placebo response rates (30%-35%), and meaningful between-group differences (25%-30%) that supp

31 In order to propose a meaningful biological interpretation, it is necessary to

32 To facilitate the discovery of meaningful biological relationships, the databases coupl

33 of disease progression and identification of meaningful biomarkers to hasten therapeutic development

34 value of sNfL as a sensitive and clinically meaningful blood biomarker to monitor tissue damage and

35 Reverse triage adds a meaningful but modest contribution and may depend on psy

36 uity 20/40 or better initially, a clinically meaningful but not statistically significant difference

37 The quantitative studies of PVSs are meaningful but usually difficult, due to their thin and

38 Meaningful Cal/Val requires intercomparison data sets wi

39 iring considerable along-track averaging for meaningful Cal/Val.

40 how the human mind organizes the world into meaningful categories and concepts.

41 multifaceted strategies to invoke clinically meaningful change in BMI among adult patients with diabe

42 SMA and control outcome measures delineates meaningful change in clinical trials in infantile-onset

43 Yet not every surprising event indicates a meaningful change in the environment.

44 There were no meaningful changes in body composition.On the basis of p

45 ting modes of disrotation, establishing that meaningful changes in dynamically controlled product sel

46 Meaningful changes in insurance status and location and

47 d bilayer properties sufficiently to produce meaningful changes in ion channel function at clinically

48 ure to the MSSP has not been associated with meaningful changes in medication use or adherence among

49 ral hemisphere in 6 h of monitoring, without meaningful changes in other variables.

50 frameworks, intense ethical discussions, and meaningful changes in social beliefs across cultures and

51 The task - distinguishing biologically meaningful chromatin interactions from massive numbers o

52 ncy to gain member state trust, and enabling meaningful civil society participation in WHO's governan

53 TERPRETATION: Nivolumab monotherapy provided meaningful clinical benefit, irrespective of PD-L1 expre

54 VR with a self-expanding prosthesis provided meaningful clinical benefits compared with SAVR, with in

55 ed on these results, olesoxime might provide meaningful clinical benefits for patients with SMA and,

56 entify the measures that best correlate with meaningful clinical differences, and assess the performa

57 bigger health care data in ways that produce meaningful clinical interpretation and to translate this

58 neurological disease, and supports PROs as a meaningful clinical outcome for use in research and clin

59 nt, oligonucleotide therapeutics are nearing meaningful clinical productivity.

60 road of translation lies ahead, the path to meaningful clinical progress has never been clearer to i

61 s in more accurate, robust, and biologically meaningful clustering results in both simulated data and

62 The algorithm extracted clinically meaningful clusters with significantly different surviva

63 emains unclear if PBRT results in clinically meaningful cognitive sparing that significantly exceeds

64 o pairwise methods implies that biologically meaningful comorbid relations may be less frequent than

65 ference in lipids intensity, which allowed a meaningful comparison of tissue lipids in control and ci

66 nd consistency in data collection will allow meaningful comparisons and provide an evidence base enab

67 it is difficult, if not impossible, to make meaningful comparisons between different peripheral nerv

68 ation to other CRVO trial cohorts will allow meaningful comparisons of outcome results across trials.

69 gray levels in all quantized images, to make meaningful comparisons of texture feature results betwee

70 ts required for developmental acquisition of meaningful complex behaviors.

71 proach to identify a panel of diagnostically meaningful compounds that may enable rapid detection of

72 inosa isolates in the presence of clinically meaningful concentrations of these antibiotics.

73 to convert the sparse and complex data into meaningful concepts that are interpretable to healthcare

74 ds to explore the data and draw biologically meaningful conclusions.

75 Use of quasiexperimental models enabled meaningful consideration of health-policy change.

76 uals in mixed-species groups in biologically meaningful contexts such as finding food in novel places

77 lating phosphoproteomic data into biological meaningful contexts.

78 ders who are not adequately prepared to have meaningful conversations about EOL planning.

79 that will determine whether concordance is a meaningful criterion for evaluating hypotheses or may pr

80 ill their potential of generating clinically meaningful data that robustly inform patient care, speci

81 who received IMRT (vs 3D-CRT) had clinically meaningful decline in FACT-LCS (21% vs 46%; P = .003).

82 arms, QOL analysis demonstrated a clinically meaningful decline in QOL in the 74-Gy arm at 3 months,

83 rimary QOL hypothesis predicted a clinically meaningful decline in quality of life (QOL) via the Func

84 reased for those words that were followed by meaningful definitions and were correlated with a decrea

85 ngth, k (an essential step in constructing a meaningful dendrogram), we designed a comprehensive stra

86 nvestigator's choice group showed clinically meaningful deterioration (10 points or more) at week 15

87 ents were included in the time to clinically meaningful deterioration analyses.

88 analogue scale, in contrast to a clinically meaningful deterioration in the investigator's choice gr

89 Median time to clinically meaningful deterioration was analysed by Kaplan-Meier me

90 Q-C30, with no domains indicating clinically meaningful deterioration.

91 reas investigator's choice led to clinically meaningful deterioration.

92 A reliable and neurobiologically meaningful diagnosis of 'neuroinflammation' or 'microgli

93 e interval, 1.3%-6.7%), there was clinically meaningful diagnostic discordance, with the FFR from the

94 oods alone may not translate into clinically meaningful diet-related health changes.

95 No meaningful difference in antidepressant treatment at 6 m

96 emained unclear whether there are clinically meaningful differences between antipsychotic treatments

97 hereby minimize the risk of being clinically meaningful differences between biosimilar and originator

98 For all outcomes, there were no meaningful differences between evaluated adverse event r

99 The model explained all meaningful differences between our low-nutrition village

100 mptoms than active surveillance; however, no meaningful differences existed in either bowel or hormon

101 lded similar estimates, but resulted in some meaningful differences in conclusions based on statistic

102 There were no clinically meaningful differences in HRQoL between lenalidomide-tre

103 No clinically meaningful differences in serious adverse events were no

104 Clinically meaningful differences were defined as a 3-point differe

105 dataset identified interesting biologically meaningful differentially co-expressed (DCX) gene sets a

106 er a clustering of genomic data results in a meaningful differentiation in phenotypes.

107 is method incompletely captures biologically meaningful differentiations.

108 turn an avalanche of quantitative data into meaningful discovery of immunological principles, predic

109 s that matter to patients should inform more meaningful discussions between healthcare professionals

110 limatic changes is difficult unless set in a meaningful ecological context.

111 tential confounding variables did not have a meaningful effect on the association between grandchild

112 properties are required to obtain physically meaningful effective material properties resulting solel

113 We stand by our original conclusions of meaningful effects of the Bedtime Learning Together (BLT

114 The clinically meaningful effects of the therapy are supported by the c

115 the NOAEL and LOAEL are not associated with meaningful effects on health and wellbeing.

116 findings demonstrated safety and clinically meaningful efficacy of allo-hMSC versus auto-hMSC in NID

117 o optimise control of blood pressure, adding meaningful efficacy to antihypertensive drug regimens.

118 were based on intention to treat; clinically meaningful efficacy was defined as 30% absolute differen

119 edicting vulnerability to climate change-but meaningful empirical data lag behind theory.

120 and the challenges of identifying clinically meaningful end points and study parameters to determine

121 radiotherapy (ConvRT) evaluating clinically meaningful end points.

122 gesting that this organ lacks a biologically meaningful endogenous stem cell pool.

123 We showed an exciting potential of PA as a meaningful endpoint for clinical trials in pediatric PAH

124 Clinically meaningful endpoints for respiratory syncytial virus (RS

125 metry performed at cyanobacterial cytosol or meaningful environmental pHs values shows a microcystin-

126 of ranks is uninformative, and a clinically meaningful estimate of the treatment effect is needed to

127 oral resolution information can provide more meaningful estimates of the magnitude and pace of climat

128 mans and nonhuman animals learn to associate meaningful events with cues in the environment, far less

129 However, this shift is not supported by meaningful evidence of its benefit over surgical aortic

130 sects are still missing, but are crucial for meaningful evolutionary considerations.

131 d for accommodation, is a profound and often meaningful experience.

132 Although it is intuitively appealing that meaningful experiences should feel good, meaningfulness

133 An avenue for assessing these meaningful exposures focuses on adducts from reactions w

134 itical challenge lies in understanding which meaningful features a network is actually learning.

135 izations in ultrathin ferroelectrics and are meaningful for the development of future electronic devi

136 ions found were small in magnitude but still meaningful from a child-development perspective, because

137 ure direction of research and translate into meaningful gains for patients.

138 agmatic play might be used for effective and meaningful game experience.

139 al profiles, which grouped into biologically meaningful gene clusters consistent with known functiona

140 l that CNVs in ADHD converge on biologically meaningful gene clusters, including ones now established

141 n lead to the identification of biologically meaningful genes in cancer biomarker studies.

142 vement information is elaborated in terms of meaningful goal-directed actions.

143 crease sensitivity to detect physiologically meaningful group differences.

144 can be clustered into distinct biologically meaningful groups by their metabolomics profiles.

145 to dysfunction, not only yielded clinically meaningful groups, but also captured behavioral and neur

146 ies in becoming aroused were also clinically meaningful (>/= 8-point change).

147 at ADT treatment has no hazard for AD and no meaningful hazard for dementia among men age 67 years or

148 Furthermore, clinically meaningful hypotension may not be as low as current guid

149 c and urinary disease is essential to make a meaningful impact in global reduction of the disease bur

150 There was no clinically meaningful impact of food on PKs.

151 With an eye toward making a more meaningful impact on response rates and modification of

152 ations in protein expression patterns have a meaningful impact on the biology of the pathogen.

153 as associated with persistent and clinically meaningful impairment of functional recovery, to 18 mont

154 ents in the nivolumab group had a clinically meaningful improvement (according to a difference of 7 p

155 rapy and continued as maintenance, yielded a meaningful improvement [corrected] in progression-free s

156 A clinically meaningful improvement from baseline in FACT-An score, a

157 ociated with slightly greater but clinically meaningful improvement in overall physical health-relate

158 d a statistically significant and clinically meaningful improvement in progression-free survival vers

159 The secondary outcome was clinically meaningful improvement using the Western Ontario McMaste

160 ts in the paired VNS group showed clinically meaningful improvements compared to 28% in controls.

161 l hypothyroidism does not provide clinically meaningful improvements in blood pressure, body mass ind

162 higher income are associated with modest but meaningful improvements in child development.

163 Conclusion CBT-I and TCC produce clinically meaningful improvements in insomnia.

164 scribed exercise and PCST provide clinically meaningful improvements in pain and function that are su

165 In order are to achieve meaningful improvements in patient safety, and create ha

166 ith statistically significant and clinically meaningful improvements in patient-reported visual funct

167 al complement inhibitor, produced clinically meaningful improvements in patients with anti-acetylchol

168 maging to DW imaging scores in the PZ yields meaningful improvements in probability of cancer detecti

169 s 3 of 4 in the rituximab group, where these meaningful improvements were also captured by video reco

170 We have shown that the amino-acid order is meaningful in mimotope motifs since they contain signifi

171 y reinstated over longer timeframes that are meaningful in the context of real-world episodic memory.

172 se loop diuretics to patients with HF yields meaningful increases in sodium exit from the proximal tu

173 antable heart pumps are capable of providing meaningful increases in survival, functional capacity, a

174 Meaningful inference in epidemiology relies on accurate

175 eory to physiology and medicine has provided meaningful information about the nonlinear aspects under

176 owever, no studies have investigated whether meaningful information can be extracted by quantifying s

177 This study provided meaningful information of applying HHP to reduce allerge

178 signals from the human white-matter contain meaningful information.

179 iologically, clinically, and therapeutically meaningful insights.

180 both forms of violence would benefit from a meaningful integrated approach.

181 ing the source to outcome continuum for more meaningful integration of exposure assessment and hazard

182 rements of many types of omics data, yet the meaningful integration of several different data types r

183 lyses provide a necessary foundation for the meaningful integration of viruses into ecosystem models

184 strated that SIPI not only searches for more meaningful interaction patterns but can also overcome th

185 entifier (SIPI), which tests 45 biologically meaningful interaction patterns for a binary outcome.

186 ollective effects of genes with biologically meaningful interactions specific to the studied phenotyp

187 and laboratory methods for the accurate and meaningful interpretation of pneumonia etiology data.

188 ltiple sources into a holistic, biologically meaningful interpretation remains challenging.

189 the utility function in ECC has a much more meaningful interpretation than any other consensus clust

190 ses that transform the auditory input into a meaningful interpretation.

191 ses that transform the auditory input into a meaningful interpretation.

192 crobes and the host increase in number, more meaningful interpretations of this information require a

193 elopment of robust genetic tools will foster meaningful investigations into how nonepithelial cell po

194 should be of fundamental importance to guide meaningful investigations into the pharmacology and func

195 Such global bias, although biologically meaningful, is often neglected when interpreting co-loca

196 icrosphere behavior in vivo and develop more meaningful IVIVCs, the in vivo release mechanisms need t

197 brain to transform natural speech sound into meaningful language, we used models based on a hierarchi

198 dent and involve the trapping of phonons for meaningful lengths of time in defect-related, localized,

199 (such as pathway information) to learn more meaningful low-dimensional representations for both cell

200 aster regulators and identifies biologically meaningful master regulators.

201 As such, approaches to achieve meaningful MCR-ALS models are characterized.

202 The ItchyQuant is a clinically meaningful measure of itch severity, demonstrating face

203 n C warrants further investigation as a more meaningful measure of renal function after critical illn

204 nificant independent indicator of clinically meaningful measures of COPD.

205 transforms current inputs into long-lasting meaningful memories.

206 nces how input elements are transformed into meaningful memory codes relies on the ability to integra

207 ter onset would result in a long-lasting and meaningful memory trace for the event but, at the same t

208 erannual timescales - into a physiologically meaningful metric for the risk of hydraulic failure.

209 This involves developing and implementing meaningful metrics of different phases of quality of IBD

210 iated with reduced risk of losing clinically meaningful mobility and upper limb disease progression m

211 ssion of nine disease-related and clinically meaningful mobility and upper limb milestones.

212 oint arm and hand movements and functionally meaningful multi-joint movements.

213 ovide an excellent opportunity for obtaining meaningful N-H bond strength data.

214 sadly, that there is no evidence to support meaningful observations of the Mpemba effect.

215 raded odor input can be transformed to yield meaningful olfactory bulb output.

216 which is neither an intuitive measure nor a meaningful one if the assumption of proportional hazards

217 ate visualizations that are not biologically meaningful, or have limited features for sharing network

218 to evaluate the system's ability to capture meaningful outcomes.

219 lating our genomic knowledge into clinically meaningful outcomes.

220 of variability in such records and suggests meaningful paleoenvironmental information can be derived

221 an and variance are determined by physically meaningful parameters and which in turn determine bias a

222 labeling, reduce the number of biologically meaningful parameters and/or rely on expensive reagents.

223 Three meaningful parameters emerge from MMRT analysis: the tem

224 this work will allow researchers to extract meaningful parameters from static quenching FRET measure

225 plet size allows the user to define the more meaningful parameters of droplet size and generation fre

226 analysis techniques to generate biologically meaningful partitions of brain structures.

227 priate allocation of MAC based on clinically meaningful patient factors.

228 ized palliative care interventions measuring meaningful patient outcomes are needed.

229 preventive service leads to improvements in meaningful patient outcomes.

230 ons with functional connectivity; showing no meaningful pattern relative to distance among brain regi

231 en for only 12 weeks results in a clinically meaningful pCR rate.

232 transient chaos, besides being a physically meaningful phenomenon by itself, provides a resolution.

233 or objective 2 was its ability to generate a meaningful policy dialogue about polio vaccines and rout

234 Our results suggest that, to achieve meaningful population suppression, tolerable rates of re

235 permafrost degradation is a prerequisite to meaningful predictions of near-future CH4 release in the

236 tational methods that guarantee biologically meaningful predictions that obey the true path rule, and

237 e detailed analyses, allowing for clinically meaningful predictions.

238 BKV genotype-specific NAb titers may be a meaningful predictive marker that allows patient stratif

239 ators are known to be involved in biological meaningful processes associated with ovarian cancer, suc

240 scription regulation, which are biologically meaningful processes that may underlie asthma risk.

241 vironment where collaborative synergy fueled meaningful progress that will impact science for decades

242 irm/refute this relationship, which may have meaningful public health implications.

243 udies in Head Start are necessary to develop meaningful public health programs.

244 a novel, yet simple, paradigm can result in meaningful pupil metrics that correlate with individual

245 wledge of clinical cancer genomics to design meaningful radiogenomics projects and explore imaging ph

246 one resulted in a significant and clinically meaningful reduction in HAM-D total score, compared with

247 ent with lisinopril is not associated with a meaningful reduction in incident AF or AFL among older a

248 hese end points was measured as a clinically meaningful reduction in the pain score and a decreased o

249 lzomib provided a significant and clinically meaningful reduction in the risk of death compared with

250 ts to mitigate alcohol abuse might result in meaningful reductions of cardiovascular disease.

251 then applied in order to define anatomically meaningful regions that will serve as the nodes of the n

252 - and 3-dimensions can be expected to reveal meaningful relationships among trees from different data

253 Differences were not clinically meaningful relative to no change in supermarket presence

254 iation, to begin supporting and prioritizing meaningful research endeavors to further evaluate these

255 Both are robust and meaningful response end points for early-phase metastati

256 e year, 50% of participants had a clinically meaningful response.

257 to treatment was 10.54 points, a clinically meaningful response.

258 Ibrutinib resulted in clinically meaningful responses with acceptable safety in patients

259 ing, >/=24 hours maybe needed for clinically meaningful restoration in platelet function.

260 provide the promising and more biologically meaningful results.

261 est to evaluate whether there is a potential meaningful role for the tracer in the clinical setting-s

262 We found no evidence to support a clinically meaningful role of CYP2C19 polymorphisms and response to

263 Thirteen and 17 meaningful RSNs could be identified in PET and fMRI data

264 nstrated by performing all of the steps on a meaningful scale.

265 urpose, passion, and the conviction of doing meaningful science.

266 e integrative approach can link biologically meaningful sets of genes to complex traits and at the sa

267 ract socially with an adult tutor to learn a meaningful song.

268 reef occurrence and ecology measured across meaningful spatial scales suggests that these coral comm

269 ge comprehension focus on activity following meaningful stimuli.

270 ese protein interaction repositories provide meaningful structural information on many endogenous mac

271 tial marker for identification of clinically meaningful subgroups.

272 focused on postoperative complications to be meaningful, such policies should require, at a minimum,

273 ne or combined with erlotinib has clinically meaningful, superior efficacy to that of erlotinib alone

274 tory support (TCS) devices afford children a meaningful survival advantage over ECMO.

275 cating that PAR-CLIP more accurately defines meaningful targeting interactions.

276 comparability of microbiome signatures at a meaningful taxonomic resolution.

277 ajor anthropogenic pressures and to identify meaningful temporal baselines for biodiversity.

278 Clinically meaningful therapeutic interventions should target body

279 The data suggest a meaningful therapeutic potential for mGluR5 NAMs in TSC,

280 f ALS provides new reasons for optimism that meaningful therapies will be identified.

281 RiVIERA identified meaningful tissue-specific enrichments for enhancer regi

282 nctional deficits of AD in these tasks it is meaningful to first study unimpaired brain function.

283 the minimum treatment intensity required for meaningful treatment effects, and determine whether trea

284 etwork meta-analysis, obtaining a clinically meaningful treatment hierarchy.

285 cally significant, but there is a clinically meaningful trend for improved long-term renal function i

286 w averaging data across subjects may obscure meaningful trends.

287 in neuroscience may fall short of producing meaningful understanding of neural systems, regardless o

288 why it is useful to consider the "item" as a meaningful unit of study when investigating early visual

289 o classify patients with FMF in a clinically meaningful way.

290 lls they learned in the museum in clinically meaningful ways at medical school.

291 ientations to respond to death in personally meaningful ways that facilitate continuity and closure,

292 The challenge of defining centrality in meaningful ways when network edges can be positively or

293 er resources are being optimally utilized in meaningful ways.

294 le modification programs achieved clinically meaningful weight and cardiometabolic health improvement

295 ients are still unable to achieve clinically meaningful weight loss.

296 We propose a physically meaningful well-specific critical SfCP criterion, which

297 igible individual or social benefits but are meaningful when performed by a large number of individua

298 imilarly, on the EORTC QLQ-H&N35, clinically meaningful worsening at week 15 was seen in no domains i

299 e participant characteristics and clinically meaningful worsening in menopause-specific quality of li

300 9% and 35% of women experienced a clinically meaningful worsening in the vasomotor, sexual, physical,