ライフサイエンスコーパス: mechanical stress

1 mMLCK is suspected to be also regulatable by mechanical stress.

2 d in a nonphotomagnetic compound by applying mechanical stress.

3 low set up, as well as when subjecting it to mechanical stress.

4 ent stem cell colonies and spatially present mechanical stress.

5 nsitive ion channels may sense the resulting mechanical stress.

6 CTCs can be released through locally applied mechanical stress.

7 able top and bottom electrode to relieve the mechanical stress.

8 nsparency while keeping high stability under mechanical stress.

9 low applied electric field (<0.2 MV/m) under mechanical stress.

10 e been suggested to be directly sensitive to mechanical stress.

11 furrow accumulation, acting in parallel with mechanical stress.

12 /VASP proteins to reinforce the cell against mechanical stress.

13 hole connector both in equilibrium and under mechanical stress.

14 teoblasts respond to different magnitudes of mechanical stress.

15 xpressing cells is their routine exposure to mechanical stress.

16 materials that are also optimized to resist mechanical stress.

17 emperature, metal ions, redox potential, and mechanical stress.

18 ring epithelial sheets highly susceptible to mechanical stress.

19 lic accumulation and relief of intranucleoid mechanical stress.

20 ucibility and stability, and tolerability to mechanical stress.

21 ssical cadherins tune adhesion and withstand mechanical stress.

22 of the atrium under conditions of excessive mechanical stress.

23 ot calcify in osteogenic medium unless under mechanical stress.

24 play any role in the response of A. annua to mechanical stress.

25 D-veliger to sound-mediated physiological or mechanical stress.

26 on signal transduction pathways, but also on mechanical stress.

27 l signaling event in response to a localized mechanical stress.

28 ly in tension wood that forms in response to mechanical stress.

29 ements, these adhesive states are exposed to mechanical stress.

30 ng structures that are capable of sustaining mechanical stress.

31 alyst for chemical change in materials under mechanical stress.

32 led; and ideal bonds that are insensitive to mechanical stress.

33 muscular attachments in order to accommodate mechanical stress.

34 altered interactions with CD3 subunits, and mechanical stress.

35 icularly prominent when cells are subject to mechanical stress.

36 was impaired, and junctions did not sustain mechanical stress.

37 ing myofibrillar degeneration in response to mechanical stress.

38 sm of BAG3-mediated muscle maintenance under mechanical stress.

39 ement of cardiac efficiency and reduction of mechanical stress.

40 ntractility in the context of chronic cyclic mechanical stress.

41 a result, the eyelid is subjected to cyclic mechanical stress.

42 study of adaptive physiological responses to mechanical stress.

43 ing, temperature, transmembrane voltage, and mechanical stress.

44 ransition are extremely sensitive to applied mechanical stress.

45 ions between the Z-disc and myofibrils under mechanical stress.

46 lar disruption in bag3 knockdown cells under mechanical stress.

47 ther is calcium-independent and activated by mechanical stress.

48 fibril vulnerability and fragmentation under mechanical stress.

49 observed in metallic glasses deforming under mechanical stress.

50 widespread mechanism to sense and respond to mechanical stress.

51 lead to the reinforcement of leaves against mechanical stress.

52 re cannot be measured independently from the mechanical stress.

53 c rods and consider its response to external mechanical stress.

54 e leaflet and commonly to areas of increased mechanical stress.

55 lead to the accrual of plaque-destabilizing mechanical stress.

56 ct, particularly when cells are subjected to mechanical stress.

57 flight muscle activation is also produced by mechanical stress.

58 els might play a neuroprotective role during mechanical stress.

59 apable of generating non-uniform patterns of mechanical stress.

60 ermed pili are necessary for adherence under mechanical stress.

61 oglial function, regulation, and response to mechanical stress.

62 ult, the disulfide bond is under substantial mechanical stress.

63 nic joint inflammation, which is worsened by mechanical stress.

64 ear deformation in response to physiological mechanical stresses.

65 city enables the microtubules' adaptation to mechanical stresses.

66 ered mucosal permeability after chemical and mechanical stresses.

67 etics, transient ASL volume, and homeostatic mechanical stresses.

68 take into account their roles in response to mechanical stresses.

69 nd repair in response to disease, injury and mechanical stresses.

70 polarity (PCP) and anisotropic tissue-scale mechanical stresses.

71 nction as a sensor/transducer of flow-induce mechanical stresses.

72 nsion of the pial surface, creating abnormal mechanical stresses.

73 on is self-organized and likely triggered by mechanical stresses.

74 , and defect size can further increase under mechanical stresses.

75 sful environment and subjected to continuous mechanical stresses.

76 Mechanical stress (30-cm H(2)O transcellular compressive

77 tural integrity despite being under constant mechanical stress [4].

78 igate the effect of the flip-flop process on mechanical stress across the bilayer and the role of CHO

79 geometry defines the spatial distribution of mechanical stress across the epithelium, which communica

80 s accumulation, relief and redistribution of mechanical stress along the protein/DNA meshwork of meio

81 In addition to signaling pathways, mechanical stresses also direct cytoskeletal protein acc

82 or was found to be stable and rugged against mechanical stress and can be used, after regeneration, f

83 ork (TM) tissue in the eye is under constant mechanical stress and continuous remodeling of ECM is cr

84 that it offers excellent resilience against mechanical stress and deformation, making it a promising

85 issue constructs were subjected to different mechanical stress and electric pacing conditions.

86 The piezoelectrochemical coupling between mechanical stress and electrochemical potential is explo

87 role in the ability of cells to both resist mechanical stress and generate force, but the precise in

88 However, how AJs adapt to mechanical stress and how this adaptation contributes to

89 in the absence of AMPK, cells generate more mechanical stress and increase fibronectin fibrillogenes

90 folds that mimic native architecture, resist mechanical stress and induce angiogenesis.

91 Although mechanical stress and injury are important factors, it i

92 ble in vitro model to examine the effects of mechanical stress and interstitial flow on biodegradable

93 differential expression of genes related to mechanical stress and jasmonate biosynthesis/signaling d

94 as well as the role of hPDLFs in monitoring mechanical stress and maintaining tissue homeostasis dur

95 pressure is increased, resulting in altered mechanical stress and ocular enlargement.

96 bination to protect axons and dendrites from mechanical stress and propose that defects in beta-spect

97 g and thin yet must withstand high levels of mechanical stress and proteolytic attack.

98 nctions autonomously to mediate responses to mechanical stress and provide in vivo evidence for a rol

99 enesis, are largely controlled by changes in mechanical stress and tension at the cell surface.

100 regulate myosin II localization at sites of mechanical stress and the cleavage furrow.

101 fibrosus (AF) caused by ageing or excessive mechanical stress and the resulting prolapse of the nucl

102 membrane disruptions are caused by excessive mechanical stress and thought to be involved in inflamma

103 ellent electrochemical attributes under high mechanical stress and thus hold promise for high-power,

104 tant mechanism by which atrial cells measure mechanical stress and translate it to alter their excita

105 We demonstrate for the first time that mechanical stresses and Rho1 GTPase control myosin dynam

106 It demonstrates a generic crosstalk between mechanical stresses and the key players of cell cycle re

107 While it is accepted that mechanical stresses and the mechanical properties of ECs

108 within the walls of arteries is regulated by mechanical stresses and vasoactive signals.

109 al factors, including temperature, humidity, mechanical stress, and chemical stimuli such as odorants

110 n isolated vessels, BPIFB4 is upregulated by mechanical stress, and its knock-down inhibits endotheli

111 anges of thermal conductivity are induced by mechanical stress, and the corresponding device is a key

112 External mechanical stress appears to make growth more homogeneou

113 ork on kinases, these results establish that mechanical stress applied through the DNA springs is ind

114 Two cellular responses to mechanical stress are a microtubule cytoskeletal respons

115 ring and fluorescence assays, explaining how mechanical stresses are accommodated.

116 re have shown that in tachypacing-induced HF mechanical stresses are associated with both structural

117 Chronic neurohormonal and mechanical stresses are central features of heart diseas

118 stasis by topoisomerases and is subjected to mechanical stress arising from replication and segregati

119 etween actomyosin-driven contraction and the mechanical stresses arising from the constraints.

120 of invasion correlated with high endogenous mechanical stress, as shown by finite element modeling a

121 anization and allows for compensation of the mechanical stress associated with oogenesis by conferrin

122 m a global inhibition of protein dynamics by mechanical-stress-associated changes in the cytoskeletal

123 d with membrane remodeling and controlled by mechanical stress at these sites is unclear.

124 ding mechanisms such as tissue buckling from mechanical stress, axon tethering, localized proliferati

125 ies contribute through their ability to bear mechanical stress, but experimental measures of their re

126 oirs facilitate cell shape change and buffer mechanical stress, but we do not know how reservoir dyna

127 ng experimental support for the induction of mechanical stress by differential growth, and a molecula

128 Cells can respond to mechanical stress by gating mechanosensitive ion channel

129 her spontaneously rupture and relax built-up mechanical stress by peeling away around the liposome or

130 opsis shoot apical meristem respond to local mechanical stresses by reorienting their growth, thereby

131 Mechanical stress can drive chemical reactions and is un

132 Mechanical stress can influence cell proliferation in vi

133 Pathological mechanical stress can lead to maladaptive cellular respo

134 Conversely, mechanical stress can provide a regulatory feedback sign

135 l cell power output and the associated chemo-mechanical stresses can also lead to catastrophic fractu

136 Many tissues in our body experience mechanical stresses caused by both internal and external

137 With pharmacological and mechanical stress causing hypertrophy, Tln1 is up-regula

138 When subjected to mechanical stress, cells lost their initial orientation

139 aluated in cell cultures subjected to cyclic mechanical stress (CMS) (20% stretching; 1 Hz) and after

140 ional collagen matrix, we show that uniaxial mechanical stress conditioning promotes 2-fold increases

141 rendered the skin vulnerable to injury under mechanical stress conditions.

142 ing suggested that predicted regions of high mechanical stress correspond to regions of tumor formati

143 protocol also diminished thermal effects and mechanical stress created during nanosecond laser ablati

144 cultured keratinocytes both to PV IgG and to mechanical stress, demonstrating that splitting at the b

145 In the 2D model, mechanical stress-dependent actin breakdown is shown to

146 cardiac hypertrophy through both ligand- and mechanical stress-dependent mechanisms.

147 Mechanical stress due to pressure and volume overload an

148 ion rely on the response of cardiac cells to mechanical stress during hemodynamic loading and unloadi

149 a drug within a capsule, without thermal or mechanical stress during manufacture.

150 ron and ion transport and help withstand the mechanical stress during the repeated electrochemical cy

151 tigated spontaneous and induced release with mechanical stress during/after simulated sunlight and ra

152 ked how fast and how far localized pulses of mechanical stress dynamically propagate through biologic

153 Mechanical stresses elicit cellular reactions mediated b

154 laments that can be stretched in response to mechanical stress encountered during colonization.

155 internally generated and externally imposed mechanical stresses, endowing the cell with the ability

156 igations of the crosstalk between an organ's mechanical stress environment and biochemical signaling

157 If the mechanical stress environment in the tissue is altered t

158 e details of volumetric expansion, fracture, mechanical stress evolution, and structural changes in s

159 tributes to the spatiotemporal regularity of mechanical stress exerted by the amnioserosa on each lea

160 blies has remained unclear, however, because mechanical stresses exerted at cell-cell junctions have

161 present a method to quantify cell-generated mechanical stresses exerted locally within living embryo

162 toskeleton protects axons and dendrites from mechanical stress, exploiting mutations in UNC-70 beta-s

163 We hypothesized that altered mechanical stress from mastication contributes to period

164 complex plays a central role in transmitting mechanical stress from the extracellular matrix to the c

165 Subsequently, exerting mechanical stresses further enhances the molecular align

166 that the ability of epithelia to respond to mechanical stress generated by one or more interactions

167 tion requires the notum epithelia to balance mechanical stress generated by the attachment of the IFM

168 of interactions linking PCP, cell shape, and mechanical stresses has recently emerged in a number of

169 Under frequent mechanical stress, hMSCs grown on our hydrogel substrate

170 insights into mechanisms that could control mechanical stress homeostasis in dynamic epithelial tiss

171 acellular transport pathways by LECs and how mechanical stress (ie, fluid flow conditioning) alters e

172 tation, caloric restriction, osmotic stress, mechanical stress, immune response, and even emotional s

173 Adaptation of vein bypass grafts to the mechanical stresses imposed by the arterial circulation

174 or chemical functionalities that respond to mechanical stress in a controlled manner.

175 in TRPC3-mediated RhoA activation induced by mechanical stress in cardiomyocytes and transforming gro

176 te zyxin regulates cytoskeletal responses to mechanical stress in culture.

177 s epithelial cells and in response to cyclic mechanical stress in human Schlemm's canal endothelial c

178 eta1 and phospho-Smad2/3 were not induced by mechanical stress in nonfibrotic lungs.

179 ement of cardiac efficiency and reduction of mechanical stress in patients with systolic dysfunction.

180 The detection of mechanical stress in polymeric materials through optical

181 ic stages when heads perceive no significant mechanical stress in utero.

182 ocytes (PC-1 knockout) and subjected them to mechanical stress in vivo (transverse aortic constrictio

183 because it is difficult to directly measure mechanical stress in vivo on sub-cellular scale, little

184 cleus, form in response to low physiological mechanical stresses in adherent fibroblasts.

185 ility and couples biochemical responses with mechanical stresses in cells, only recently have we begu

186 ally asymmetric environment with non-uniform mechanical stresses in radial and circumferential direct

187 of cell wall material that is controlled by mechanical stresses in the wall.

188 duces myofibrillar disorganization caused by mechanical stress, in vitro mechanical stretch experimen

189 tissue, and biochemical evidence of chronic mechanical stress, including increased angiotensin II ty

190 lso found in other tissues known to be under mechanical stress, including stress fibers in migratory

191 to the plasma membrane frequently encounter mechanical stresses, including high hydrostatic pressure

192 l suspensions can propagate and absorb large mechanical stresses, including impacts and shocks.

193 Vasoconstrictors and mechanical stress induce remodelling of the focal adhesi

194 However, the mechanisms governing mechanical stress-induced activation of L-type calcium c

195 timal actin-binding affinity that allows for mechanical stress-induced protein accumulation.

196 e) significantly but incompletely attenuates mechanical stress-induced up-regulation of CHI3L1 expres

197 the maintenance of bone mass, whereas excess mechanical stress induces bone resorption.

198 Mechanical stress induces lung fibrosis, and epithelia-m

199 We found that mechanical stress induces supercoils and plectonemes in

200 included effects on lung hyperinflation and mechanical stress, inflammation, excessive mucus product

201 how the coupling between vibronic states and mechanical stresses inherent to conjugated polymers can

202 Furthermore, mechanical stress inhibits Dll4 expression and leader ce

203 Similarly, caveolae transduce mechanical stress into PM lipid alterations that, in tur

204 mechanisms have been suggested to translate mechanical stress into structural changes, one of them b

205 complex interactions among joint tissues and mechanical stresses involved in the OA process.

206 Mechanical stress is an often underappreciated contribut

207 ely 20 nm, and manifests itself clearly when mechanical stress is applied to the membrane.

208 Altered mechanical stress is detected by a cell-associated compl

209 It is well known that adequate mechanical stress is essential for the maintenance of bo

210 Mechanical stress is pervasive in egress routes of malig

211 , unlike heat- or pressure-driven reactions, mechanical stress is rarely applied isometrically, obscu

212 sue integrity especially where resistance to mechanical stress is required.

213 gle, extended conformation in the absence of mechanical stress, it can be easily bent by forces of ph

214 Mechanical stress mainly affects transcription of HIF-1a

215 In the asthmatic airway mechanical stress may contribute to enhanced YKL-40 leve

216 pecies, which could reduce its resistance to mechanical stresses, may depend on an inhibition of the

217 vivo, providing an ideal model for studying mechanical stress-mediated decrease in smooth muscle con

218 erphase cell is influenced by cell adhesion, mechanical stress, neighbour topology, and planar polari

219 Plant cells in tissues experience mechanical stress not only as a result of high turgor, b

220 lastomer (TPE) eluates, reflect the stronger mechanical stress of batch testing.

221 ensuring that both organs can withstand the mechanical stress of embryo elongation; mistiming of epi

222 fically, the MoS2 films are able to generate mechanical stresses of about 17 megapascals-higher than

223 this damage is not due to DNA breakage from mechanical stress on chromatin in the deformed nucleus.

224 To explore the direct effects of mechanical stress on lung fibrotic formation, human lung

225 Understanding the effect of mechanical stress on membranes is of primary importance

226 n limitation but instead to the influence of mechanical stress on the driving force for reaction.

227 lamellar vesicles to determine the effect of mechanical stress on the liquid/liquid miscibility tempe

228 al encounters a target, it expands, imposing mechanical stress on the wire and altering its magnetic

229 cifically focuses on impacts of LVAD-related mechanical stress on VWF structural stability and adhesi

230 e imposes very harsh chemical, physical, and mechanical stresses on biospecimens, significantly compr

231 es of material fatigue, the concentration of mechanical stresses on pre-existing defects in the micro

232 better understanding of the role of dynamic mechanical stresses on the fate of hMSCs but also for th

233 turing of outer oxide-acetate layers through mechanical stressing or shearing, thus initiating a casc

234 Local alignment of cell velocity and mechanical stress orientation-a phenomenon dubbed "plith

235 Experimental perturbation of mechanical stress pattern further supported a contributi

236 onse of osteoblasts to varying magnitudes of mechanical stress play a key role in switching the mode

237 Mechanical stress plays a key role in many genomic proce

238 Mechanical stress plays an essential role in tissue deve

239 are a source of YKL-40 and demonstrate that mechanical stress potently induces CHI3L1 expression lea

240 membrane, enabling a direct transduction of mechanical stress produced by magnetic torque acting on

241 Mechanical stress producing head injury is associated wi

242 rs that are required to measure directly the mechanical stress profile of 3D tissues embedded within

243 entified an amplification mechanism in which mechanical stress promotes the microtubule response to s

244 s of the fiber direction are introduced, the mechanical stress provides a robust directional cue for

245 Ucns improved muscle resistance to mechanical stress provoked by repetitive tetanizations.

246 tal and theoretical approaches and show that mechanical stresses regulate bacterial cell wall growth.

247 Mechanical stress regulates development by modulating ce

248 DNA and dsRNA in sequence contexts and under mechanical stresses relevant to their biology.

249 ternal mechanical strain, how HDs respond to mechanical stress remains poorly understood.

250 h myofibrillar structure is maintained under mechanical stress remains unclear.

251 icted to provide only a tiny fraction of the mechanical stress required to overcome turgor, is largel

252 dly promotes epithelial damage and decreased mechanical stress resistance of the skin before inductio

253 sites that experience high and low levels of mechanical stress, respectively.

254 hat the opening dynamics are dictated by the mechanical stress response of the cell wall matrix, and

255 e first time that innate immunity transduces mechanical stress responses through the matrix component

256 and inner centromeric protein (INCENP) is a mechanical stress-responsive system.

257 Aggregates created by harsh mechanical stress showed the largest number of subvisibl

258 anism induced by angiotensin II (Ang II) and mechanical stress, showed a remarkable similarity betwee

259 We previously showed that mechanical stress similar to that experienced during bro

260 In this study, we report that mechanical stress specifically induces varicosities in t

261 After 8 weeks, wounds subjected to different mechanical stress states underwent immunohistochemical a

262 e full cell shows unprecedented tolerance to mechanical stress such as bending and cutting, where it

263 ominent in tissues subject to high levels of mechanical stress such as the epidermis and heart.

264 rovessels of the brain are very sensitive to mechanical stresses such as observed in traumatic brain

265 stitute a membrane reservoir that can buffer mechanical stresses such as stretching or osmotic swelli

266 et there arise unanticipated fluctuations of mechanical stress that are severe, emerge spontaneously,

267 igh echogenicity in HFU images and the large mechanical stress that exceeded the yield strength.

268 ive pressure ventilation exposes the lung to mechanical stresses that can exacerbate injury.

269 id (HA), collagen and the spatial origins of mechanical stresses that close off blood vessels was inv

270 cate that closure of the tunnel is driven by mechanical stresses that develop within a cross-linked a

271 Cytoskeletal actin assemblies transmit mechanical stresses that molecular sensors transduce int

272 t, under conditions of chronically increased mechanical stress, the integrin signaling pathway is ove

273 heart is subject to continuous metabolic and mechanical stress, the proteasome plays a particularly i

274 s most commonly observed at sites of maximal mechanical stress: the leaflet tips and the commissures.

275 yosin assemblies to adapt dynamically to the mechanical stresses they convey and direct their own rem

276 ng distances directly by the transmission of mechanical stress through the DNA itself, without any re

277 ace, and to resolve and quantify patterns of mechanical stress throughout the surrounding matrix.

278 When applying mechanical stress to a bulk metallic glass it responds w

279 Using a novel apparatus to apply mechanical stress to cell-cell junctions, we showed that

280 Ball-milling utilizes mechanical stress to modify properties of carbon nanotub

281 Experiments use thermal, chemical, or mechanical stress to perturb the folding equilibrium for

282 owing application of an external vibrational mechanical stress to that tissue.

283 y (3D-MTC) is a technique for applying local mechanical stresses to living cells.

284 is the mechanotransduction pathway by which mechanical stress transduced by the microtubule network

285 ofluidic constrictions, and we calibrate the mechanical stresses using gel beads.

286 eletal proteins during cytokinesis and under mechanical stress, using fluorescence recovery after pho

287 Cells generate mechanical stresses via the action of myosin motors on t

288 For ATP secretion, a stepwise yet uniform mechanical stress was imposed onto MC3T3-E1 cells.

289 We present an active, purely mechanical stress wave isolator that consists of short c

290 skin barrier functions (immune suppression, mechanical stress), we studied the possible role of FLG

291 ting the response of this modular protein to mechanical stress, we studied its force-induced unfoldin

292 8, Akt, and glycogen synthase kinase 3 after mechanical stress were strongly blunted in Tln1cKO mice.

293 atent and can be triggered by applying local mechanical stress, whereby crystals leap several centime

294 llin I form a mechanosensor that responds to mechanical stress, which could account for spindle-indep

295 n-uniform growth can lead to accumulation of mechanical stress, which in the context of two-dimension

296 ch assays, but after subjecting the cells to mechanical stress, which is normally present in wounds,

297 est that transcarbamoylation is activated by mechanical stress, which we attribute, on the basis of D

298 t the onset of MET correlates with a peak in mechanical stress within the HFR and changes in HPC migr

299 conformations that are capable of relieving mechanical stress within the template.

300 ogy, monolayers sustain, detect and generate mechanical stresses, yet little is known about their mec