ライフサイエンスコーパス: mechanism mediating

1 rter localization studies to investigate the mechanisms mediating [(14)C]L-serine (a system L substra

2 results provide direct evidence for a neural mechanism mediating a simple and widespread form of stat

3 structures provides a context for resolving mechanisms mediating ABA control of protein-protein inte

4 Structural mechanisms mediating ABA receptor recognition and signal

5 es into account the diversity of biophysical mechanisms mediating adaptation and the different ways i

6 The intrarenal mechanisms mediating adaptation to variations in dietary

7 Our data reveal a novel mechanism mediating adaptive and concomitant homeostatic

8 ers compared with normal tissue, and a major mechanism mediating adaptive responses to reduced O2 ava

9 on is critical for characterizing the neural mechanisms mediating adaptive behavior in humans, as wel

10 ent of the VTA is imperative for elucidating mechanisms mediating adolescent vulnerability to drug ad

11 Mechanisms mediating adult enteric neurogenesis are larg

12 ted information is known about the molecular mechanisms mediating aggressive behavior in swine.

13 e pathogenesis and provides new insight into mechanisms mediating aldosterone production and hyperten

14 However, the molecular mechanisms mediating AMPAR exocytosis induced by NMDAR a

15 However, it is unclear whether the molecular mechanisms mediating AMPAR trafficking during homeostati

16 is a critical need to understand the neural mechanisms mediating anxiety symptoms.

17 fferential vulnerability of these regions to mechanisms mediating apoptosis, oxidative stress and aut

18 To study the neurophysiological mechanisms mediating assignment of motivational meaning,

19 Our findings present a unique molecular mechanism mediating astrocytic/neuronal crosstalk that r

20 ogether, these findings suggest hypothalamic mechanisms mediating attenuation of hypoglycemia-induced

21 However, the underlying signaling mechanism mediating autophagy is not well understood.

22 ffered tremendous insight into the molecular mechanisms mediating behavioral and phenotypic plasticit

23 for this by investigating the interneuronal mechanisms mediating behavioral choice between two auton

24 microbial sepsis, the cellular and molecular mechanisms mediating beneficial effects are controversia

25 ge-induced transcriptome to inform molecular mechanisms mediating binge eating susceptibility and est

26 , we gained novel insight into the molecular mechanisms mediating bone loss in ovariectomized (OVX) m

27 nt alphaABD clustering is a unique molecular mechanism mediating both integrity and reassembly of the

28 ively, our study uncovers a novel regulatory mechanism mediating both iron resistance and adaptation

29 Possible mechanisms mediating both incidence and severity effects

30 enetics has transformed our understanding of mechanisms mediating brain disorders.

31 Thus, the major mechanisms mediating brain information processing are al

32 -MyD88 and TLR4-TRIF axes represents a novel mechanism mediating C. jejuni-induced inflammatory respo

33 requires large quantities of Ca(2+) yet the mechanisms mediating Ca(2+) dynamics in enamel cells are

34 first to tumor-draining lymph nodes, but the mechanisms mediating cancer cell invasion into the lymph

35 tudies establish NEK6 signaling as a central mechanism mediating castration-resistant prostate cancer

36 However, the mechanisms mediating cell proliferation after hypoxia or

37 udied in the cerebellum and spinal cord, the mechanisms mediating cell-fate decisions in the brainste

38 tion of the NF-kappaB pathway as a candidate mechanism mediating circadian immune responses.

39 ese findings help to characterize the neural mechanisms mediating cisplatin-induced anorexia, advanci

40 Current understanding of the physiological mechanisms mediating climate-induced forest mortality li

41 Mechanisms mediating closure of the dorsal vertebrae are

42 Our investigation into mechanisms mediating CNS actions of insulin led us to as

43 unctional loss of D2 receptors is a critical mechanism mediating cocaine-induced glutamate plasticity

44 ion of Abeta alone may be a relatively minor mechanism mediating cognitive benefits of the interventi

45 Candidate mechanisms mediating commensal microbiota's pro-osteocla

46 outstanding opportunities for uncovering the mechanisms mediating cooperative behavior, an exemplar o

47 Although molecular mechanisms mediating cortical interneuron migration have

48 omatin remodeling as an essential epigenetic mechanism mediating CPC differentiation.

49 n health and disease; however, the molecular mechanisms mediating CXCR4 signaling remain poorly under

50 The molecular mechanisms mediating cylindromatosis (CYLD) tumor suppre

51 licate both classic and nonclassic endocytic mechanisms mediating DAT trafficking.

52 Cell-biological mechanisms mediating delamination are, however, poorly u

53 cohol dependence, but the specific molecular mechanisms mediating dependence-induced neuroadaptations

54 We examined the ionic mechanisms mediating depolarization-induced spike activi

55 Mechanisms mediating differences between subtypes includ

56 y homozygous variation may provide a general mechanism mediating disease phenotypes and the genetic l

57 pite fundamental structural differences, the mechanisms mediating DNA accessibility by FACT are conse

58 These finding suggest that the mechanism mediating DRN 5-HT(7) receptor induction of ph

59 Molecular mechanisms mediating duplicate preservation remain incom

60 ge at the level of MAPKs with the signalling mechanisms mediating E2 beta- and catecholamine-induced

61 ortant structural insight into the molecular mechanisms mediating EBI2 function and may facilitate fu

62 ses to examine the time course of the neural mechanisms mediating echo suppression.

63 fur seals allows us to distinguish neuronal mechanisms mediating EEG changes from those mediating be

64 Understanding molecular mechanisms mediating epileptogenesis is critical for dev

65 Here we have identified a novel mechanism mediating Epo-dependent EpoR internalization.

66 ng their cargo to target cells; however, the mechanisms mediating exosome-cell interactions are poorl

67 ngs illuminate novel neuronal and behavioral mechanisms mediating food intake reduction by GLP-1.

68 Here, we have determined the intracellular mechanisms mediating gastrin-dependent gene expression.

69 Although the mechanisms mediating genotoxic NF-kappaB activation have

70 plasm assembly has been well characterized, mechanisms mediating germ plasm inheritance are poorly u

71 ngs illuminate novel neuronal and behavioral mechanisms mediating ghrelinergic control of cognitive a

72 odels will be important for establishing the mechanisms mediating grid firing.

73 recent advances in our understanding of the mechanisms mediating growth cone guidance with a particu

74 To define the mechanisms mediating H2 S-induced vasodilatation, microd

75 rkers of hypoglycemia and use them to assess mechanisms mediating HAAF and its reversal.

76 l cell function have been described, but the mechanisms mediating hematopoietic dysfunction remain un

77 The mechanisms mediating hematopoietic stem and progenitor c

78 The cellular and molecular mechanisms mediating histamine-independent itch in prima

79 Moreover, the mechanisms mediating homeostatic immunity at this interf

80 BK-induced migration represents a novel mechanism mediating homing of circulating angiogenic pro

81 Yet, the molecular and cellular mechanisms mediating homing of B cells to the vessel wal

82 linically to acquire HSC for transplant, the mechanisms mediating HSC release are not completely unde

83 Mechanisms mediating immunity to malaria remain unclear,

84 ohol dependence and a key pathophysiological mechanism mediating increased propensity to relapse.

85 nting and territory defence are two possible mechanisms mediating infection costs.

86 trategies that target molecular and cellular mechanisms mediating inflammation and the neurobiologica

87 The immunopathogenic mechanisms mediating inflammation in multiorgan autoimmu

88 Our findings provide new insight into the mechanisms mediating inherited and acquired noncirrhotic

89 To define the mechanisms mediating inhibition of IFNgamma-induced gene

90 However, molecular mechanisms mediating initial bacterial adhesion to morph

91 Little is known about mechanisms mediating initiation and identity of specific

92 ve in the relapsed tumors, but the molecular mechanisms mediating intrinsic or acquired resistance to

93 patients develop resistance to TKIs, and the mechanisms mediating intrinsic resistance to EGFR-TKIs i

94 However, the mechanisms mediating intrinsic resistance to MEK inhibit

95 The authors examine whether the neural mechanisms mediating irritability differ between bipolar

96 ently activated oncogenes, but the molecular mechanism mediating its critical role in transformation

97 of PKCalpha and identify the non-proteasomal mechanism mediating its degradation.

98 wever, important issues, such as the precise mechanisms mediating its actions and the unique versus r

99 functional brain connectivity, the molecular mechanisms mediating its association with schizophrenia

100 order, but the neural pathways and molecular mechanisms mediating its effects are unclear.

101 ver, the resistin receptor and the molecular mechanisms mediating its effects in the hypothalamus, cr

102 However, the downstream mechanisms mediating its function are unclear.

103 However, the mechanisms mediating its therapeutic effects are not ful

104 elevance of these findings to humans and the mechanisms mediating JunB function are not fully underst

105 However, the neurocognitive mechanisms mediating learning and recognition of voices

106 We show that mechanisms mediating leukocyte slow rolling and emigrati

107 tochondrial ROS production is not one of the mechanisms mediating lifespan extension at lower T.

108 to long-term synaptic plasticity, a cellular mechanism mediating long-term memory.

109 These data establish LTP-IE as a candidate mechanism mediating loss of visual responsiveness within

110 To investigate mechanisms mediating low-dose GnRH suppression of GABAer

111 The mechanism mediating many of these responses remains unkn

112 However, host genomic mechanisms mediating microbial control of intestinal gen

113 We have investigated the mechanism mediating ncOGT induction with glucose depriva

114 To understand the molecular mechanisms mediating neuroblastoma metastasis, we develo

115 To characterize the presynaptic mechanisms mediating new synaptic growth induced by patt

116 ese observations have been variable, and the mechanisms mediating nuclear PKGI translocation are inco

117 gene expression and providing a biochemical mechanism mediating O3-derived formation of oxidized lip

118 beta-amyloid (Abeta) neuropathology, as one mechanism mediating observed functional improvements.

119 Next, in search of the mechanism mediating PA-induced autophagy, we found incre

120 We examined potential epigenetic mechanisms mediating pair-bond regulation and found that

121 The neuronal mechanisms mediating patch-leaving decisions remain unkn

122 One likely mechanism mediating pathogenesis is excessive transcript

123 infections, but effective treatments and the mechanisms mediating pathogenesis remain elusive.

124 ive changes in NR function and the molecular mechanisms mediating pathogenesis.

125 Our study provides evidence of a novel mechanism mediating pathological dysregulation of basal/

126 To isolate and characterize the neural mechanisms mediating perception of biological motion, we

127 athogenic bacteria, the underlying molecular mechanisms mediating phage adsorption to S. aureus are s

128 very is largely empirical, and the molecular mechanisms mediating phosphospecific binding are poorly

129 latively little is known about the molecular mechanisms mediating phytoplankton host-virus interactio

130 These results suggest that brainstem neural mechanisms mediating pitch processing show preferential

131 Therefore, we investigated central mechanisms mediating pituitary-adrenal activation during

132 The brain sites and mechanisms, mediating post-ictal analgesia, are unclear.

133 Understanding the regulatory mechanisms mediating PRNP gene expression is highly rele

134 fferentiation, but little is known about the mechanisms mediating promyogenic effects of cAMP.

135 IL-17 production is most likely an important mechanism mediating protection from inappropriate intest

136 pment of Pneumocystis pneumonia, specific Th mechanisms mediating protection are not well understood.

137 malaria; however, a limited understanding of mechanisms mediating protection is a major barrier to va

138 vivo and to decipher the possible underlying mechanisms mediating protection.

139 may represent a previously unknown class of mechanism mediating protein interaction and function.

140 However, molecular mechanisms mediating PS protection in injured neurons re

141 The mechanisms mediating PTP1B overexpression in obese and d

142 s various sizes of vesicles, is the dominant mechanism mediating rapid and slow endocytosis within ~1

143 nce imaging (fMRI) to investigate the neural mechanisms mediating reactivation-induced updating in me

144 However, elucidating the cell type and mechanisms mediating recovery has been difficult because

145 We probed the mechanisms mediating regulation of early growth response

146 macrophages/dendritic cells is an important mechanism mediating renal tubule epithelial regeneration

147 nd resistance, we investigated the molecular mechanisms mediating repression of glucocorticoid recept

148 have been defined, little is known about the mechanisms mediating resolution.

149 l regulators of cell migration; however, the mechanisms mediating RSK-dependent motility remain incom

150 tant novel insights into the neurobiological mechanisms mediating sex differences in ASD prevalence.

151 regs, and demonstrate an important molecular mechanism mediating Skp2 function in balancing immune to

152 The neural mechanisms mediating social status have become increasin

153 r two-photon guidance elucidate the synaptic mechanisms mediating spike suppression to contrast steps

154 To define the mechanisms mediating spontaneous recovery of function af

155 While molecular mechanisms mediating ST-induced intestinal secretion hav

156 monophosphate (c-di-GMP), yet the signaling mechanisms mediating such a global switch are poorly und

157 terizing the dopaminergic and frontostriatal mechanisms mediating such behavior.

158 The mechanisms mediating such genomic responses to targeted

159 lished paradigm to investigate the cognitive mechanisms mediating such response conflict.

160 However, the molecular mechanisms mediating tau truncation and aggregation duri

161 further insight into the complex regulatory mechanisms mediating TGF-beta2 signaling and ECM product

162 tabolism as a novel and potentially critical mechanism mediating the age-dependent and regional loss

163 s been hypothesized to represent a necessary mechanism mediating the beneficial cognitive effects of

164 This study identifies a cellular mechanism mediating the beneficial effect of HDLs on bet

165 However, the molecular mechanism mediating the cell survival effect remains elu

166 Our data suggest that a key mechanism mediating the deficit involves ubiquitin C-ter

167 t telomere attrition might represent a novel mechanism mediating the detrimental effects of hostility

168 tention and perception and reveal the neural mechanism mediating the disposition to see the 'forest b

169 c modifications provide a putative molecular mechanism mediating the effect of folic acid supplementa

170 We studied the molecular mechanism mediating the effect of GSK-3beta activation/i

171 inase activities of PKM2 may be an important mechanism mediating the effects of growth signals in pro

172 We also demonstrated a novel mechanism mediating the function of PDGF-DD.

173 IL-2 production has long been recognized, a mechanism mediating the inhibition remains unclear.

174 Our findings identify a central mechanism mediating the inhibitory effects of BDNF on fe

175 signaling pathways as an activity-dependent mechanism mediating the inhibitory effects of GluN3A on

176 Here we investigated the intracellular mechanism mediating the involvement of the RhoGDIalpha/R

177 hanges in perceptual templates as a powerful mechanism mediating the learning of statistical regulari

178 atients' tumor and suggesting that an immune mechanism mediating the observed antitumor effect.

179 Together, these findings identify a novel mechanism mediating the oncogenic function of SULF2 in H

180 a provide novel evidence for a post-semantic mechanism mediating the production of surface errors, an

181 To elucidate the mechanism mediating the reduction in apo A-I expression

182 Inhibition of GSK3beta is likely a key mechanism mediating the therapeutic activity of Tanshino

183 regulates Kappa expression, unraveling a new mechanism mediating the well-established interactions be

184 oughout the brain, but the precise molecular mechanisms mediating the actions of GLP-1 and its long-a

185 oanatomical, behavioral, and pharmacological mechanisms mediating the anorexia produced by PACAP in t

186 lking has been extensively investigated, the mechanisms mediating the behavioral choice to activate i

187 not been explored in animals, and the neural mechanisms mediating the behavioral effects of gains and

188 mic control, but the knowledge on underlying mechanisms mediating the beneficial effects remains inco

189 These findings provide new insights into the mechanisms mediating the beneficial vascular effects of

190 Intricate mechanisms mediating the calcium-alkali syndrome depend

191 However, little is known about the mechanisms mediating the cellular impairments induced by

192 neurotransmitter release, but the molecular mechanisms mediating the cooperation between these molec

193 ronchial epithelial cells and elucidated the mechanisms mediating the damage.

194 nding regarding the basic pathophysiological mechanisms mediating the development of pressure ulcers

195 solved questions pertaining to the molecular mechanisms mediating the direct interaction between Nedd

196 To determine the molecular mechanisms mediating the effect of PGC-1alpha on VLDL as

197 m of this study was to explore the molecular mechanisms mediating the effects of estrogen (E(2)) on H

198 These results contribute to clarifying the mechanisms mediating the effects of HIU on whey proteins

199 To explore the neural mechanisms mediating the effects of OT in macaque monkey

200 ew will provide an overview of the molecular mechanisms mediating the generation of soluble cytokine

201 e vanilloid receptor TRPV1 is one of the key mechanisms mediating the hyperalgesic effects of inflamm

202 chronic inflammatory phenotype.The molecular mechanisms mediating the impact of environmental factors

203 The mechanisms mediating the induction and development of Br

204 r, the long-term physiological relevance and mechanisms mediating the intake-suppressive effects of V

205 To understand the mechanisms mediating the interactions between betaAR and

206 In searching for mechanisms mediating the metabolic actions of FoxO1, we

207 w, we discuss recent progress in elucidating mechanisms mediating the molecular sorting of neuromodul

208 unloading alter t-tubule structure, but the mechanisms mediating the normally tight regulation of th

209 ulate stomatal development; however, the key mechanisms mediating the perception and relay of the CO2

210 well characterized, less is known about the mechanisms mediating the positive response to this growt

211 Molecular mechanisms mediating the progression of ductal carcinoma

212 ng the existence of redundant or alternative mechanisms mediating the prolonged lifespan of neonatal

213 Understanding the neurochemical mechanisms mediating the prosocial effects of MDMA could

214 c, and viral pathogens and discusses the key mechanisms mediating the regulatory function of type I I

215 This research suggests that the neural mechanisms mediating the relation between affect and cho

216 Mechanisms mediating the spread of dilatation from local

217 ndings shed light on dynamically interacting mechanisms mediating the stabilization of hippocampal an

218 s raises a question concerning the molecular mechanisms mediating the success of this lineage.

219 The precise mechanism or mechanisms mediating the thermal sensitivity of TRPV1 ar

220 The mechanisms mediating the transition from the migratory t

221 m of SPF mice demonstrate possible molecular mechanisms mediating the up-regulated osteoclastogenesis

222 gap in our understanding of the biochemical mechanisms mediating their effects.

223 derived GBM in vitro and in vivo, as well as mechanisms mediating their efficacy.

224 However, the mechanisms mediating their emergence and subsequent refi

225 undergo chemotherapies each year, the neural mechanisms mediating their side effects are unknown.

226 infant relationship, and the neurobiological mechanisms mediating them that needs to be the focus of

227 toll-like receptor 4 (TLR4) as an underlying mechanism mediating these effects and establish that TLR

228 sease (NAFLD) in animal models; however, the mechanism mediating these effects is unclear.

229 nd oncogene-mediated transformation, but the mechanism mediating these effects is unknown.

230 To reveal the potential signaling mechanism mediating these effects, levels of phosphoryla

231 omized mice, and we determined the molecular mechanism mediating these effects.

232 We found a novel mechanism mediating these results in which PU.1, miRNA-2

233 nnels to investigate the putative structural mechanism mediating these results.

234 t only a minority of loci have the molecular mechanisms mediating these associations been characteriz

235 modeling was used to investigate the neural mechanisms mediating these changes in spectral power in

236 The mechanisms mediating these contradictory effects are unk

237 However, the molecular mechanisms mediating these deleterious effects remain un

238 However, the mechanisms mediating these distinct outcomes remain poor

239 hippocampal neurogenesis, but the molecular mechanisms mediating these effects are poorly understood

240 e variants is TMEM18, although the molecular mechanisms mediating these effects remain entirely unkno

241 However, the molecular mechanisms mediating these effects remain poorly underst

242 ase and liver-related disease mortality, but mechanisms mediating these effects remain unknown.

243 To investigate potential mechanisms mediating these effects, brain glucose metabo

244 To further explore mechanisms mediating these effects, we fed young (age 25

245 and paclitaxel therapy and investigated the mechanisms mediating these effects.

246 roid hormones on cognition, and the putative mechanisms mediating these effects.

247 The mechanisms mediating these features are poorly understoo

248 rties that contribute to metastasis, but the mechanisms mediating these functions remain poorly defin

249 c gain-of-function (GOF) properties, but the mechanisms mediating these functions remain poorly defin

250 cell invasive growth and metastasis, yet the mechanisms mediating these functions still largely remai

251 is needed to identify the precise cognitive mechanisms mediating these kinds of risky choices in rat

252 n do normally developing children, the brain mechanisms mediating these pathophysiologic abnormalitie

253 However, the underlying mechanisms mediating these processes are unclear.

254 To explore molecular mechanisms mediating these responses, we examined effect

255 The neural mechanisms mediating these side effects remain elusive d

256 One important mechanism mediating this AR reactivation is intratumoral

257 and mental illness; however, the biological mechanism mediating this association remains largely unk

258 fspring to consume nicotine, but the precise mechanism mediating this behavioral phenomenon is unclea

259 ducing hepatic glucose output, the molecular mechanism mediating this effect had remained elusive unt

260 n due to the polymorphism is most likely the mechanism mediating this effect.

261 pigmentation and melanoma, but the molecular mechanism mediating this function was entirely unknown.

262 d no evidence for a reactive oxygen-mediated mechanism mediating this mtDNA loss.

263 ant-pathogen interactions, but the molecular mechanism mediating this phenomenon is poorly understood

264 genes is essential for color vision, but the mechanism mediating this process is poorly understood.

265 However, the detailed mechanism mediating this process remains enigmatic.

266 e identify a candidate serotonergic cellular mechanism mediating this process.

267 ce in vertebrates and invertebrates, but the mechanism mediating this regulation is poorly defined.

268 gned to form a visuotopic map, but the basic mechanisms mediating this alignment remain elusive.

269 lioma spread, but the cellular and molecular mechanisms mediating this are poorly understood.

270 ute respiratory distress syndrome (ARDS) but mechanisms mediating this association are unknown.

271 omenon is clearly established, the molecular mechanisms mediating this cellular event remain elusive.

272 the key steps in prostate tumorigenesis, the mechanisms mediating this cellular process are still lar

273 eurons is robustly decreased by 50%, but the mechanisms mediating this change are unknown.

274 required for intestinal homeostasis, but the mechanisms mediating this down-regulation are incomplete

275 channel activation, but functional signaling mechanisms mediating this effect are unclear.

276 in-deficient diabetes and to investigate the mechanisms mediating this effect.

277 eferred to as gate control, but the cellular mechanisms mediating this form of neuroplasticity are po

278 The mechanisms mediating this functional plasticity are poor

279 s; however, little is known about the neural mechanisms mediating this important choice behavior.

280 ssembly at the plasma membrane; however, the mechanisms mediating this incorporation process remain p

281 otransmitter release; however, the molecular mechanisms mediating this plasticity are not known.

282 t brain plasticity, but the precise cellular mechanisms mediating this process are unknown [1].

283 However, the molecular mechanisms mediating this process remain unclear, and th

284 the HER2 targeting antibody trastuzumab, the mechanisms mediating this resistance remain elusive.

285 We characterized the mechanisms mediating this response and identified an ext

286 The mechanisms mediating this sensitized or "primed" immune

287 The mechanisms mediating this so-called 'ductular reaction'

288 y role in motivating continued drug use, the mechanisms mediating this type of drug-induced plasticit

289 ses, but little is known about the molecular mechanism mediating those interactions.

290 Mechanisms mediating TNFSF15:DR3 contributions to PRR ou

291 However, the mechanisms mediating toxic heavy metal-induced gene expr

292 cells are resistant to TRAIL, suggesting the mechanism mediating TRAIL-induced apoptosis is complex.

293 However, the mechanisms mediating Treg migration to neonatal skin are

294 However, the structures and mechanisms mediating TRPV1's pronounced temperature sens

295 This study has shed light on molecular mechanisms mediating tumor aggressiveness and also provi

296 oglial lineage genes, and reveals unexpected mechanisms mediating tumor viability and invasion, inclu

297 The mechanisms mediating uptake are not well understood.

298 In contrast to mechanisms mediating uptake of intracellular bacterial p

299 Further, the inflammatory mechanisms mediating viral infection-induced bone loss d

300 Trying to identify the mechanisms mediating XBP1s neuroprotection, we found tha