ライフサイエンスコーパス: mechanism that underlie

1 jections and reveal the cellular and circuit mechanisms that underlie a rate-dependent switch in the

2 Here we investigated the molecular mechanisms that underlie acquired resistance to BRAFi an

3 ted thrombosis is a major pathophysiological mechanism that underlies acute coronary syndromes, and t

4 holine (ACh) release may represent a crucial mechanism that underlies age-related deficits in learnin

5 vances in identifying and characterizing the mechanisms that underlie age-associated defective adapti

6 rovide guidance for understanding the neural mechanisms that underlie age-dependent reductions in the

7 Identifying the molecular mechanisms that underlie aging and their pharmacological

8 ur findings offer critical insights into the mechanisms that underlie AIPL1 function in health and di

9 framework, we can ask questions about common mechanisms that underlie all three.

10 onal pentameric structure in cell lines, and mechanisms that underlie alpha7 receptor assembly in neu

11 odology will make it possible to dissect the mechanisms that underlie altered glycoconjugate recyclin

12 ies, it is critical to better understand the mechanisms that underlie AML progression.

13 s been observed in a variety of systems, the mechanisms that underlie AMPAergic scaling have been con

14 s new insight into genetic and physiological mechanisms that underlie an ecologically relevant form o

15 onsider possible physiological and cognitive mechanisms that underlie an individual's ability to make

16 The mechanisms that underlie and dictate the different biolo

17 These data shed new light on the molecular mechanism that underlies anti-CD3-mediated immune resett

18 uired to gain protection and, lastly, 3) the mechanisms that underlie any association.

19 gaps concerns a refined understanding of the mechanisms that underlie arsenic mobilization, particula

20 Although much is known about the brain mechanisms that underlie associations with dangerous tas

21 ful for investigating the pathophysiological mechanisms that underlie asthma and the development of m

22 The mechanisms that underlie AVM formation remain poorly und

23 s a potential route to unraveling the neural mechanisms that underlie awareness itself.

24 co-culture model recapitulates key molecular mechanisms that underlie bacteria-induced neutrophil tra

25 ocyte IL-1beta production represents a novel mechanism that underlies behavioral complications associ

26 Our understanding of the genetic mechanisms that underlie biological processes has relied

27 sight into the biochemical and physiological mechanisms that underlie bleeding and clotting disorders

28 ts have been made to investigate the genetic mechanisms that underlie body composition.

29 ring [Ca2+]i flux is central to the study of mechanisms that underlie both normal cardiac function an

30 e comparable results indicate similar neural mechanisms that underlie both the ETS and EAS effects.

31 ates from this epithelium, but the molecular mechanisms that underlie breast epithelial hierarchy rem

32 ings identify and characterize an epigenetic mechanism that underlies CAM-DR and suggest that kinase

33 hese powerful tools can reveal the molecular mechanisms that underlie carbohydrate-mediated signal tr

34 ort efforts to better understand the genetic mechanisms that underlie CD34(+) frequency.

35 breast carcinogenesis, the molecular genetic mechanisms that underlie cell transformation are less cl

36 The molecular mechanisms that underlie chromosome 9 open reading frame

37 ss the regulation of chylomicron production, mechanisms that underlie chylomicron dysregulation, and

38 , we review our current understanding of the mechanisms that underlie circuit remodeling during retin

39 ognized risk factor for dementia, the neural mechanisms that underlie cognitive impairment in T2DM re

40 These results identify a molecular mechanism that underlies complex interactions between th

41 Details of the pathophysiologic mechanisms that underlie complex disorders, such as the

42 ce in vertebrates, but the proximate genetic mechanisms that underlie complex patterns of craniofacia

43 SAM also enabled identification of potential mechanisms that underlie components of memory, thus reve

44 the structures, kinetics, thermodynamics and mechanisms that underlie conformational exchange process

45 requires p38alpha MAPK, but transcriptional mechanisms that underlie cytokine-driven selectin ligand

46 To elucidate the biochemical mechanisms that underlie detoxification and pathogen-imm

47 se data provide insight into chromatin-based mechanisms that underlie developmental regulation and el

48 tools for elucidating the neuropathological mechanisms that underlie different disorders.

49 To investigate mechanisms that underlie different modes of cross talk,

50 The mechanisms that underlie directional cell migration are

51 The molecular mechanisms that underlie distinct instances of necroptos

52 rphological diversity, and the developmental mechanisms that underlie diversification are of signific

53 es; therefore, elucidation of the epigenetic mechanisms that underlie drug resistance may greatly con

54 dies have therefore uncovered the regulatory mechanisms that underlie early thyroid organogenesis and

55 nectivities during reward processing suggest mechanisms that underlie early vulnerabilities for devel

56 findings provide insight into the molecular mechanisms that underlie enteric symbiont-stimulated sys

57 a continuum of the same pathogenic allergic mechanisms that underlie EoE and thus might constitute a

58 understanding of the molecular and cellular mechanisms that underlie epitope preferences in T cell p

59 However, mechanisms that underlie ERG expression in AML and how i

60 ave a severe macrocytic anemia; however, the mechanisms that underlie erythropoiesis dysfunction in t

61 portant for serotonin function; however, the mechanisms that underlie experience-dependent transcript

62 Molecular and cellular mechanisms that underlie FA-induced damage are poorly un

63 Here we describe the neural mechanism that underlies females' sucrose rejection in o

64 tem to help elucidate the specific metabolic mechanisms that underlie folate-associated birth defects

65 e not rich enough to allow identification of mechanisms that underlie food insecurity and overweight

66 is work establishes the molecular origin and mechanism that underlie formation of unique carbon cage

67 eurodevelopmental, and psychopharmacological mechanisms that underlie genetic variation-associated co

68 Moreover, our results shed light on a mechanism that underlies genomic instability in sporadic

69 ore, essential to understand the biochemical mechanisms that underlie genomic regulation.

70 Defining the mechanisms that underlie glial communication could enabl

71 anding of the neurobiological and behavioral mechanisms that underlie greater risk of heroin addictio

72 fundamental element to our knowledge of the mechanisms that underlie H2O2 electrochemistry.

73 epidemiologists often seek to determine the mechanisms that underlie health disparities.

74 examine the molecular, cellular, and circuit mechanisms that underlie how memories are made, stored,

75 Unravelling the complex mechanisms that underlie human brain astrocyte-neuron in

76 he systematic investigation of the molecular mechanisms that underlie human diseases.

77 ls is essential for identifying the cellular mechanisms that underlie human genetic traits and diseas

78 ogenic mutations are rare, and the molecular mechanisms that underlie increased ROCK1 and RhoA expres

79 e perceptual importance of pitch, the neural mechanisms that underlie it remain poorly understood.

80 t in understanding vitamin D biology and the mechanisms that underlie its actions.

81 though its role in signal processing and the mechanisms that underlie its availability are not well u

82 ated by the heterogeneous pathophysiological mechanisms that underlie its clinical presentation, whic

83 The relevant computational and motivational mechanisms that underlie its heterogeneity, however, are

84 nosinusitis (CRS), little is known about the mechanisms that underlie its pathogenesis.

85 ent insights into the cellular and molecular mechanisms that underlie its pivotal roles in atheroscle

86 romere protein A (CENP-A), but the molecular mechanisms that underlie its remarkable stability remain

87 for Bipolar Disorder although the molecular mechanisms that underlie its therapeutic effects are und

88 outlines our recent studies on the synaptic mechanisms that underlie ketamine action, in particular

89 nd intra-lineage diversity in the targetable mechanisms that underlie KRAS-driven cancers, limited ph

90 hat have been studied extensively to examine mechanisms that underlie learning.

91 Here, we report an unexpected molecular mechanism that underlies ligand-dependent enhancer activ

92 not only aid in the discovery of the genetic mechanisms that underlie local adaptation but also provi

93 ptor function, yet little is known about the mechanisms that underlie long-lasting effects.

94 To gain further insights into the molecular mechanisms that underlie MamK dynamics and function, we

95 seeding will help clarify the physiological mechanisms that underlie mast seeding.

96 Our results suggest that the prefrontal mechanisms that underlie mature performance on the antis

97 The mechanisms that underlie MDM4 upregulation in cancer cel

98 the identification of molecular and cellular mechanisms that underlie memory storage.

99 a novel molecular contributor to the complex mechanisms that underlie metastasis in colorectal cancer

100 In particular, little is known about the mechanisms that underlie metastasis of cancer, and even

101 eceptor activity, in most cases the detailed mechanisms that underlie modulation are poorly understoo

102 However, the molecular mechanisms that underlie modulation of cancer stem cells

103 The fundamental mechanisms that underlie mt dysfunction in HF have not b

104 findings provide insights into the molecular mechanisms that underlie mutagenesis and are relevant to

105 behaviors to facilitate the study of neural mechanisms that underlie naturalistic behaviors.

106 paper focuses on the cellular and molecular mechanisms that underlie neural-cardiac interactions dur

107 With the goal of identifying signaling mechanisms that underlie neuronal circuit integration in

108 xtension (CE) is a fundamental morphogenetic mechanism that underlies numerous processes in vertebrat

109 This study provides evidence of neuronal mechanisms that underlie odor-object segregation on a ti

110 However, the molecular mechanisms that underlie oncogene-induced replication st

111 A better understanding of the mechanisms that underlie pain generation has potential t

112 o MOG may offer widespread implications into mechanisms that underlie pain pathways.

113 Mechanisms that underlie partitioning of the genome into

114 tor, NOGGIN, generating a reaction-diffusion mechanism that underlies patterning.

115 rmal developmental biology and key molecular mechanisms that underlie pediatric cancer, which are the

116 Several groups studying molecular mechanisms that underlie plant cell signal transduction

117 estigations into the structure and molecular mechanisms that underlie plant PSII function.

118 Although the specific mechanisms that underlie Plin5 lipid droplet storage pro

119 l populations is an evolutionarily conserved mechanism that underlies population survival upon stress

120 However, the mechanisms that underlie PRC2 recruitment and spreading

121 cue, yet little is known about the synaptic mechanisms that underlie processing this cue in the infe

122 Hence, by unraveling the molecular mechanisms that underlie proneural induction, cell fate

123 dy) may prove useful and timely to elucidate mechanisms that underlie protection (as well as virulenc

124 The genomic mechanisms that underlie pulmonary immune responses to f

125 The mechanisms that underlie recovery after injury of the ce

126 to establish causality between the molecular mechanisms that underlie reproductive division of labor,

127 ropose a positive appraisal style as the key mechanism that underlies resilience.

128 ns and have identified some of the genes and mechanisms that underlie resistance.

129 Advances in understanding of the molecular mechanisms that underlie restless legs syndrome could le

130 50K mutation in the pathogenic mitochondrial mechanism that underlies retinal ganglion cell (RGC) deg

131 appeared to encompass a putative yet-unknown mechanism that underlies root development under LN.

132 However, little is known of the molecular mechanisms that underlie RpaB functions.

133 also affected by gain control, an inhibitory mechanism that underlies saturation of neural responses

134 t a recent surge of studies of the proximate mechanisms that underlie search behavior offers a new op

135 The need to investigate mechanisms that underlie self-assembly has motivated thi

136 d metabolic diseases; however, the molecular mechanisms that underlie SFA-induced lipotoxicity remain

137 well-defined lineages can uncover molecular mechanisms that underlie significant evolutionary transi

138 ing field of social neuroscience, the neural mechanisms that underlie social encounters are only begi

139 lopment and in mediating synaptic plasticity mechanisms that underlie some forms of learning and memo

140 The molecular mechanisms that underlie spleen development and congenit

141 The mechanisms that underlie such branch loss are largely un

142 indings raise new questions about the neural mechanisms that underlie such dynamic representational s

143 erimental paradigm to investigate the neural mechanisms that underlie such goal-dependent modulation.

144 tau pathology and physiology, the structural mechanisms that underlie such interactions remain to be

145 anding the selective pressures and molecular mechanisms that underlie such tremendous morphological v

146 To identify the mechanisms that underlie susceptibility to EBV lytic act

147 The mechanisms that underlie susceptibility to infection in

148 However, the molecular mechanisms that underlie symbiont-mediated host immunity

149 rain disorders, yet we know little about the mechanisms that underlie synaptic vulnerability.

150 The pathological mechanisms that underlie T helper type 2 cell-driven (Th

151 However, mechanisms that underlie t-volume changes are poorly und

152 ells, we uncovered a microtubule-independent mechanism that underlies the accumulation of molecules i

153 The regulatory mechanism that underlies the Ace2-to-Ace pathological sw

154 Overall, our results reveal a regulatory mechanism that underlies the activation of Shh target ge

155 cal adhesion maturation suggests a molecular mechanism that underlies the beneficial effect of Bis-T-

156 by entry into the lymphatic system may be a mechanism that underlies the entry and spread of other t

157 ation/microcalcification and may clarify the mechanism that underlies the genetic association between

158 s glucokinase activation may represent a CNS mechanism that underlies the oft-described phenomena of

159 Our findings provide evidence of a mechanism that underlies the protective effects of AKT2

160 The mechanism that underlies the regulation of PICK1-Ago2 bi

161 d daily caloric intake is a major behavioral mechanism that underlies the relation between sleep loss

162 The mechanism that underlies the temperature sensitivity in

163 We use the PTM approach to elucidate the mechanism that underlies the wide range of improvements

164 ponses, and they serve to focus attention on mechanisms that underlie the acute calcemic response to

165 However, the mechanisms that underlie the association between asthma

166 hormones and adipokines, could be a clue to mechanisms that underlie the association with dementia a

167 ea of the macaque monkey to study the neural mechanisms that underlie the behavioral consequences of

168 vided little insight regarding the potential mechanisms that underlie the benefits of retrieval pract

169 s the implications of these findings for the mechanisms that underlie the biosynthesis of these newly

170 and discuss the current understanding of the mechanisms that underlie the broad, yet highly cell- and

171 aspects of impulses and desires, the neural mechanisms that underlie the capacity for control have e

172 To investigate the molecular mechanisms that underlie the cardiomyopathy associated w

173 ohepatitis, the delineation of the potential mechanisms that underlie the cardiovascular benefit and

174 telligent behavior by studying the molecular mechanisms that underlie the chemotactic responses of Es

175 The physiological mechanisms that underlie the coordination of angiogenesi

176 In bacteria, the mechanisms that underlie the coordination of chromosome

177 ovided detailed insights into many molecular mechanisms that underlie the detection of signals and th

178 To identify the mechanisms that underlie the differences in function and

179 s well characterized at the molecular level, mechanisms that underlie the direct effect of light on b

180 The biochemical and evolutionary mechanisms that underlie the diversity of this DNA-bindi

181 Transcriptional mechanisms that underlie the dose-dependent regulation o

182 curate understanding of the social influence mechanisms that underlie the dynamics of popularity.

183 e net effects of the complex and contrasting mechanisms that underlie the ecosystem consequences of b

184 Gaining a greater understanding of the mechanisms that underlie the effect of exposure to air p

185 hic pulmonary fibrosis (IPF), the pathogenic mechanisms that underlie the effects of advancing age re

186 he cellular components and signaling control mechanisms that underlie the etiology of reactive stroma

187 lenecks during transmission to shed light on mechanisms that underlie the evolution and propagation o

188 Understanding the genetic mechanisms that underlie the evolution of weedy crop rel

189 e known, little is known of the molecules or mechanisms that underlie the female contribution to sper

190 The mechanisms that underlie the focal delivery of AChRs to

191 The molecular mechanisms that underlie the formation of chromosome ter

192 We discuss neural circuit mechanisms that underlie the generation and regulation o

193 However, the mechanisms that underlie the highly specific assembly of

194 ries of experiments to identify the cellular mechanisms that underlie the hyperexcitability reported

195 Understanding the brain mechanisms that underlie the impact that emotional assoc

196 is work summarizes research on the molecular mechanisms that underlie the increased risk of cancer de

197 tes are maintained by synaptic activity, the mechanisms that underlie the initiation and robust rhyth

198 foundation for future studies uncovering the mechanisms that underlie the initiation, maintenance, an

199 In this review, we describe the known mechanisms that underlie the loss of immune regulation i

200 allows for modeling and detailed analysis of mechanisms that underlie the M-SOB effect in not only MS

201 The molecular and cellular mechanisms that underlie the many roles of macrophages i

202 pathways, and the genetic and developmental mechanisms that underlie the morphogenesis of TME struct

203 imating Ne , and identifying key demographic mechanisms that underlie the Ne to census population siz

204 re has not been implemented with the genetic mechanisms that underlie the organization of gene cluste

205 al to cancer cell invasion, but the specific mechanisms that underlie the particularly invasive pheno

206 An increased understanding of the mechanisms that underlie the pathogenesis of castrate re

207 f asthma; however, little is known about the mechanisms that underlie the pathogenesis of the disease

208 ion to animal models, much of the biological mechanisms that underlie the pathology of SZ remain unkn

209 en made in understanding the basic molecular mechanisms that underlie the pathophysiology of sepsis,

210 vide insights into distinguishing the neural mechanisms that underlie the predisposition to drug addi

211 Understanding the molecular mechanisms that underlie the presence or absence of a sp

212 rovide novel insight into the dynamic neural mechanisms that underlie the processing of somatosensory

213 ideal platform for dissecting the molecular mechanisms that underlie the prognostic differences betw

214 eview the current understanding of molecular mechanisms that underlie the promising therapeutic effec

215 The evolutionary mechanisms that underlie the rapid evolution of centrome

216 podocytopathy; therefore, understanding the mechanisms that underlie the regulation of calcium/calci

217 s in understanding the systemic and cellular mechanisms that underlie the regulation of iron homeosta

218 of inteins, whereas the second describes the mechanisms that underlie the remarkable ability of intei

219 Thus, an understanding of the molecular mechanisms that underlie the resistance to ART and the p

220 s of early environment on the neuromolecular mechanisms that underlie the risk to develop anxiety and

221 Understanding the trafficking mechanisms that underlie the role of ciliary compartment

222 model should aid in dissecting the molecular mechanisms that underlie the role of PML in gammaherpesv

223 The mechanisms that underlie the sequestration of these sub-

224 male mice to disease; however, the molecular mechanisms that underlie the sex- and strain-dependent d

225 on-free approach for inferring the molecular mechanisms that underlie the shape of protein distributi

226 understanding of the cellular and molecular mechanisms that underlie the sleep-dependent regulation

227 These observations reveal mechanisms that underlie the specific programming and pr

228 Here we focus on mechanisms that underlie the stimulation of G by ephrins

229 rther dissect the complex pathophysiological mechanisms that underlie the tissue specificity of the m

230 Gaining insights into the regulatory mechanisms that underlie the transcriptional variation o

231 studies have characterized the neural coding mechanisms that underlie the transformation from natural

232 oubts remain about the precise photophysical mechanism that underlies their peculiar spectroscopic pr

233 iew different functions of SCs, the cellular mechanisms that underlie them and the signals that bias

234 sensitization of viral membranes is a common mechanism that underlies these Broad-SAVE.

235 The molecular mechanism that underlies these observed differences has

236 s the discrete biomechanical and biochemical mechanisms that underlie these architectural changes and

237 However, the physiological mechanisms that underlie these changes are not fully und

238 rties, but the activity-dependent plasticity mechanisms that underlie these changes are poorly unders

239 he essential tremor cerebellum, although the mechanisms that underlie these changes remain poorly und

240 cover molecular, cellular, and circuit-level mechanisms that underlie these deficits and successfully

241 The mechanisms that underlie these developmental stage-speci

242 iscovery to an exposition of neurobiological mechanisms that underlie these disorders and subsequentl

243 To investigate the network-level mechanisms that underlie these dynamics, we developed no

244 ocal inhibitory interneurons, as well as the mechanisms that underlie these dynamics.

245 sorders, but little is known about the brain mechanisms that underlie these effects in alcohol consum

246 prior reports, current understanding of the mechanisms that underlie these effects is limited.

247 attenuate cognitive decline in aging and the mechanisms that underlie these effects should be investi

248 Future studies may explain the mechanisms that underlie these findings.

249 of On DS RGCs, and biophysical and synaptic mechanisms that underlie these functional differences.

250 f Notch signaling, and dissect the molecular mechanisms that underlie these functions in hematopoieti

251 uch interactions can yield insights into the mechanisms that underlie these functions.

252 hibit impaired extinction retrieval, but the mechanisms that underlie these hormone-based discrepanci

253 g of the genetic architectures and molecular mechanisms that underlie these interactions, we comprehe

254 Little is known about the neural mechanisms that underlie these memory processes.

255 exclusive hypotheses concerning the neuronal mechanisms that underlie these perceptual improvements.

256 is known about sex differences in the neural mechanisms that underlie these phenomena.

257 However, the mechanisms that underlie these phenotypes remain unknown

258 ubstantially expanded knowledge of potential mechanisms that underlie these phenotypes, including a p

259 Understanding the molecular mechanisms that underlie these plastic changes is a majo

260 The neural mechanisms that underlie these processes are not well un

261 nd burial of C within inland waters, yet the mechanisms that underlie these processes are poorly cons

262 ological neural plasticity, and studying the mechanisms that underlie these processes, including rein

263 However, in most patients, the mechanisms that underlie these symptoms are unknown.

264 g the field's understanding of the molecular mechanisms that underlie these syndromes.

265 ental health of adults and children, and the mechanism that underlies this association has been assum

266 The molecular mechanism that underlies this dual substrate specificity

267 Here, we have probed the mechanism that underlies this requirement for cross-talk

268 The mechanism that underlies this switch between maternal an

269 The molecular mechanisms that underlie this adaptation remain unknown.

270 nt, little is known about the neurocognitive mechanisms that underlie this adaptive phenomenon, since

271 However, the neuronal mechanisms that underlie this altered functional state r

272 However, the molecular mechanisms that underlie this balance remain elusive.

273 re-CP to the CP, but the cellular plasticity mechanisms that underlie this change are poorly understo

274 le is known about the molecular and cellular mechanisms that underlie this communication.

275 o shed light on the molecular and regulatory mechanisms that underlie this complex process.

276 The mechanisms that underlie this coordination are currently

277 However, the molecular mechanisms that underlie this dendritic remodeling remai

278 serve as a valuable tool for analyses of the mechanisms that underlie this devastating side effect of

279 To investigate the molecular mechanisms that underlie this dichotomy, we studied epig

280 The mechanisms that underlie this difference are unclear.

281 ry than their cortical counterparts, but the mechanisms that underlie this difference are unclear.

282 ate, inhibits angiogenesis but the molecular mechanisms that underlie this effect are not known.

283 Elucidation of the molecular mechanisms that underlie this effect will further our un

284 However, the molecular mechanisms that underlie this genetic interaction remain

285 e development of insulin resistance, but the mechanisms that underlie this link remain unclear.

286 However, the mechanisms that underlie this phenomenon remain poorly u

287 The mechanisms that underlie this phenotype are controversia

288 identified as a model of mania; however, the mechanisms that underlie this phenotype, and the changes

289 s CD4 independence provide new insights into mechanisms that underlie this phenotype.

290 However, the cellular and molecular mechanisms that underlie this priming effect remain poor

291 ent and provide the mechanical and molecular mechanisms that underlie this process.

292 ory (ARM) was described decades ago, but the mechanisms that underlie this protein synthesis-independ

293 nforcing; however, the neuronal circuits and mechanisms that underlie this reinforcement are still no

294 Although the pathophysiological mechanisms that underlie this relationship are poorly un

295 However, the mechanisms that underlie this severe pathogenicity remai

296 The mechanisms that underlie this specialization are not wel

297 The molecular mechanisms that underlie this switch have not been defin

298 However, the molecular biophysical mechanism that underlies upstream cell polarization and

299 ile parameters that can be used to elucidate mechanisms that underlie variations in CM function.

300 We also identify dynamical mechanisms that underlie various features of this ISR be