ライフサイエンスコーパス: mechanism underlying

1 n and resistance to mTOR inhibitors, but the mechanism underlying 4E-BP1 downregulation in tumors rem

2 umented in preclinical models, the molecular mechanisms underlying acquired resistance are largely un

3 This may partly explain the mechanism underlying adipocyte hyperplasia that occurs m

4 ll apoptosis may be an important part of the mechanism underlying ADPKD pathogenesis.

5 ly, we present data implicating Prosapip1 in mechanisms underlying alcohol self-administration and re

6 been important in unravelling the molecular mechanisms underlying ALS.

7 Mechanisms underlying altered beta-cell function in agin

8 Among neurobiological mechanisms underlying antidepressant properties of ketam

9 However, the mechanisms underlying appropriate downregulation of trab

10 lular phenotype for investigating pathogenic mechanisms underlying AS and identifying novel therapeut

11 is critical for clinical recovery; however, mechanisms underlying ATII cell proliferation and spread

12 Recent studies have demonstrated conflicting mechanisms underlying atrial fibrillation (AF), with the

13 lone, our understanding of the systems-level mechanisms underlying attentional control remains limite

14 studies have suggested that both epigenetic mechanisms underlying AUD and the efficacy of HDAC inhib

15 Insight into the mechanisms underlying bacterial adhesion is critical to

16 hich together offer novel insights about the mechanisms underlying behavioral laterality in humans.

17 nd improve existing ideas for neural network mechanisms underlying behaviorally observed improvements

18 hyperbilirubinemia, investigating molecular mechanisms underlying bilirubin-induced encephalopathy,

19 nfluence exerted by the two eyes on cortical mechanisms underlying binocular vision [1, 2], and exper

20 The immunological mechanisms underlying C-IRIS are incompletely defined an

21 a widespread post-translational modification mechanism underlying cell physiology.

22 ed cell volume irrespective of the molecular mechanism underlying cell swelling.

23 The mechanisms underlying cell- and process-specific effects

24 upporting both monogenic and complex genetic mechanisms underlying CHD.

25 There is an acute need to decipher mechanisms underlying chemoresistance and identify new t

26 These results support a potential mechanism underlying clinical observations that allergic

27 iscoveries have changed our understanding of mechanisms underlying CNS immune privilege and CNS drain

28 cytes in the nucleus accumbens in the neural mechanisms underlying cocaine seeking.

29 l knowledge about the molecules and cellular mechanisms underlying coloboma formation.

30 provide a unique opportunity to examine the mechanisms underlying conscious perception.

31 Unfortunately, the genetic mechanisms underlying craniocardiac malformations remain

32 ction has not been possible as the molecular mechanisms underlying CRY2 interactions are unknown.

33 instability, it is pivotal to understand the mechanism underlying Cse4 regulation.

34 hold voltage-activated currents might be the mechanism underlying defective repetitive firing.

35 erocytosis, by lesional macrophages, but the mechanisms underlying defective efferocytosis and its po

36 enomic studies, we aimed to identify genetic mechanisms underlying depression and anxiety after traum

37 facilitate the elucidation of the biological mechanisms underlying depression, however, its complex e

38 n (LogMiNeR), and apply it to understand the mechanisms underlying differential responses to influenz

39 ecades, will require continued research into mechanisms underlying disease prevention, pathogenesis,

40 e probes may be readily adapted to study the mechanisms underlying disease progression on all mucosal

41 obstruction for understanding the molecular mechanism underlying drought tolerance.

42 ltrafiltration (UF) membranes to unravel the mechanisms underlying early stage membrane biofouling.

43 hese results show that the spiking-initiated mechanisms underlying electrical synapse plasticity are

44 tic chemistry in elucidating the fundamental mechanisms underlying electronic polarization transfer a

45 emonstrate this model's utility to delineate mechanisms underlying epileptogenesis after pediatric br

46 To better understand the mechanisms underlying ESCRT-mediated formation of ILVs,

47 results provide important insights into the mechanism underlying eukaryotic transcription terminatio

48 The mechanisms underlying exercise-induced mitophagy have no

49 es and discusses current evidence on central mechanisms underlying exercised-induced pain and analges

50 The elucidation of the mechanisms underlying folate action has been challenging

51 sts that pulmonary vascular disease is a key mechanism underlying Fontan failure and supports further

52 in cytosolic pH (pHcyto ) probably influence mechanisms underlying forms of synaptic plasticity with

53 ote CNG and HCN channel opening, the precise mechanism underlying gating remains poorly understood.

54 o the understanding of the complex molecular mechanism underlying Gaucher disease and the regulation

55 ional investigation to elucidate the precise mechanism underlying gene-length dependent changes in ex

56 ors, can profoundly improve understanding of mechanisms underlying genetic associations.

57 recent studies have investigated the complex mechanisms underlying GR functions.

58 The molecular mechanisms underlying growth and dormancy in woody peren

59 A further understanding of the mechanism underlying HBoV1 helper-dependent AAV2 replica

60 Here we report a general molecular mechanism underlying hippocampal inhibitory synapse deve

61 Here, we review the principal physiological mechanisms underlying homeostatic failure during cold ex

62 We review the mechanisms underlying host defense in the very young, an

63 The mechanism underlying how CRPC gains resistance toward ho

64 en identified in many human cancers, but the mechanism underlying how hPOT1 mutations initiate tumori

65 The molecular mechanisms underlying human brain evolution are not full

66 However, the neural mechanisms underlying human motivation are far from bein

67 will allow the study of the unique molecular mechanisms underlying human pluripotent stem cell differ

68 ribute to our understanding of the molecular mechanisms underlying hyperproliferation of the palmopla

69 ediated reduction identified as the dominant mechanism underlying hypoxic vasodilation.

70 eview the most recent understanding of basic mechanisms underlying IgE-mediated food allergies and no

71 Mechanisms underlying impulse control disorders and dysk

72 esent a unifying neurocognitive framework of mechanisms underlying information sharing at scale (vira

73 Mechanisms underlying information storage have been depi

74 The results shed light on the molecular mechanisms underlying its ability to induce hallucinatio

75 in cancer would enable the discovery of key mechanisms underlying its development and progression.

76 genic roles in various cancers; however, the mechanisms underlying its dysregulation and functions in

77 the ocular surface and identify the cellular mechanisms underlying its effects on ocular immune homeo

78 sinophils and malignant mast cells, identify mechanisms underlying its endocytosis, and demonstrate w

79 ng role for TCF7L1 in skin and elucidate the mechanisms underlying its tumorigenic capacity.

80 ed in alternative splicing and the molecular mechanism underlying JMJD6-regulated alternative splicin

81 tional work to define the central biological mechanisms underlying JS and other ciliopathies.

82 (KATP)-channels, thus suggesting a possible mechanism underlying KCC2-dependent insulin release.

83 However, pathophysiological mechanisms underlying knowlesi malaria, and of the age-r

84 oenergetics may be an important contributing mechanism underlying late-onset Alzheimer's disease (LOA

85 city is thought to be the principal neuronal mechanism underlying learning.

86 We identified 3 mechanisms underlying local progression in the remnant p

87 Here, we propose a mechanism underlying losartan's benefits by selectively

88 etween brain areas has been suggested as the mechanism underlying loss of consciousness in anesthesia

89 l of computational tools to elucidate causal mechanisms underlying loss of protein function in loss-o

90 ere offers a unique opportunity to study the mechanisms underlying lymphatic vessel formation, remode

91 However, the mechanism underlying lysosomal deficits in AD remains po

92 NA modifications and reveals the biochemical mechanisms underlying m(6)A function in the cell.

93 ese results demonstrate a Hedgehog-dependent mechanism underlying mammalian intrinsic ureteropelvic j

94 review the literature on the neurobiological mechanisms underlying maternal and paternal care, especi

95 es a unique system to decipher the molecular mechanisms underlying MCS formation.

96 However, molecular mechanisms underlying MEF2C haploinsufficiency syndrome

97 Improved understanding of the mechanisms underlying migrations allows for improved man

98 This study investigates mechanisms underlying MMN impairments in schizophrenia u

99 provide a valuable model to study the brain mechanisms underlying motor learning.

100 However, the mechanisms underlying mutant p53 GOF are not well unders

101 e studies have been primarily focused on the mechanisms underlying mutant SOD1 cytotoxicity.

102 Further understanding of the mechanisms underlying mutp53 protein accumulation and ga

103 Despite the knowledge of the mechanisms underlying neural and mechanical functions, t

104 Inflammation is emerging as a critical mechanism underlying neurological disorders of various e

105 ecording and stimulation to probe the neural mechanisms underlying neuronal computations.

106 3 oncogenic gain of function but also on the mechanisms underlying nonmutational wtp53 inactivation,

107 wledge about the dynamics and the regulatory mechanisms underlying nuclear movements in root epiderma

108 emergentist perspective on the computational mechanism underlying numerosity perception, its developm

109 voSIGNIFICANCE STATEMENT We have uncovered a mechanism underlying olfactory receptor sensitivity regu

110 However, the mechanisms underlying opposition to Polycomb silencing a

111 Immunological mechanisms underlying OR differ according to the type of

112 The resolution of the mechanisms underlying p53 dysfunction will better addres

113 ential broad-spectrum anti-viral targets.The mechanism underlying packaging of genomic RNA into viral

114 estrate neuronal delamination and may inform mechanisms underlying pathological epithelial cell detac

115 However, the neural circuit mechanisms underlying persistent neuronal encoding withi

116 lation was proposed several decades ago, the mechanisms underlying PHB contribution to sporulation ha

117 piRNA-rich nict-1 locus could define a novel mechanism underlying phoretic interactions.Nematodes use

118 Our findings reveal key control mechanisms underlying photoprotective dissipation, with

119 r in progeria, research on HGPS can identify mechanisms underlying physiological aging.

120 rovide a framework for further exploring the mechanisms underlying PM phosphoinositide regulation.

121 t abortive infection represents an important mechanism underlying progressive CD4(+) T cell depletion

122 posit that dynamic ligand binding may be the mechanism underlying protean agonism of dualsteric ligan

123 However, the molecular mechanisms underlying protein glycosylation are still po

124 the mitochondrial targeting signal, but the mechanisms underlying Prx1 distribution to distinct mito

125 of this study provide insight into molecular mechanisms underlying PTSD and suggest that mGluR5 may b

126 The mechanisms underlying red blood cell (RBC)-mediated hypo

127 tural studies presented here thus reveal the mechanism underlying redox-regulation of AP-1 Fos/Jun tr

128 on regeneration and uncover a novel cellular mechanism underlying regenerative vs non-regenerative te

129 These findings provide insight into the mechanisms underlying regulation of insect odorant recep

130 amyotrophic lateral sclerosis (ALS), but the mechanisms underlying repeat-induced disease remain inco

131 Mechanisms underlying reservoir stability are unclear.

132 nce to ivermectin is now widespread, but the mechanisms underlying resistance are unresolved.

133 Unlike in mouse models, the mechanisms underlying SAg-associated immunosuppression i

134 ndings within a novel framework in which the mechanisms underlying scale selection are impaired in de

135 technological advances, it is expected that mechanisms underlying several disease states involving t

136 Yet the developmental-genetic mechanisms underlying sex-specific development remain po

137 -signaling network in order to elucidate the mechanisms underlying signal integration.

138 ic spectral mosaics may provide insight into mechanisms underlying sleep pathophysiology.

139 Following an introduction to the mechanisms underlying spatial navigation and how they re

140 Cellular mechanisms underlying spike-timing-dependent plasticity

141 However, the mechanisms underlying squamous cell carcinoma susceptibi

142 e the first to reveal the neurocomputational mechanisms underlying subjective cost-benefit valuation

143 gest the necessity of ongoing studies of the mechanisms underlying subsequent adult human oligodendro

144 d flow has been considered to be the primary mechanism underlying such impedance based microflow sens

145 eed for experimental studies to identify the mechanisms underlying such antecedent effects.

146 isk of diabetes mellitus; however, the exact mechanisms underlying such association have not been elu

147 o alter emotional responses to them, and the mechanisms underlying such changes.

148 oth regulatory and pathogenic roles, yet the mechanisms underlying such opposing effects remain uncle

149 Our data demonstrate that the mechanism underlying synchronised membrane ballooning re

150 cers, suggesting that this might be a common mechanism underlying synergy in the control of cardiac g

151 eir composition and architecture, many basic mechanisms underlying target recognition and cleavage ar

152 findings establish an exocytosis-coordinated mechanism underlying the cellular pathfinding guided by

153 However, the mechanism underlying the disrupting effect of KYNA remai

154 The mechanism underlying the effect of ILT3.Fc on tumor cell

155 The mechanism underlying the evolution of white flowers in I

156 Here we explored the genetic mechanism underlying the expression of discrete mating s

157 A major mechanism underlying the genetic diversification of infl

158 However, the mechanism underlying the involvement of RPS15A in HCC pa

159 We show that the mechanism underlying the observed changes in cBLI signal

160 f mRNA translation is emerging as a unifying mechanism underlying the pathogenesis of many neurodegen

161 could be a general essential feature of the mechanism underlying the phenomenon of allergenicity.

162 e have identified a putative neurobiological mechanism underlying the potent combination of psychothe

163 vation of expected stimuli is a facilitating mechanism underlying the powerful contextual behavioral

164 The precise molecular mechanism underlying the regulation of early B cell lymp

165 In this study, we elucidated the neuronal mechanism underlying the response at an anatomical, func

166 abundance by IDOL as a post-transcriptional mechanism underlying the structural and functional plast

167 protect synapses, our results unravel a new mechanism underlying the synaptotoxic action of AbetaOs

168 t disrupts this activity, which could be one mechanism underlying the therapeutic benefit.

169 ture mediated oxygen limitation is a general mechanism underlying the thermal tolerance of embryos.

170 Our data suggest a molecular mechanism underlying the transition between a better-kno

171 homologous recombination (HR), the molecular mechanism underlying the tumor suppressor functions of F

172 gs identify a new chromatin-based epigenetic mechanism underlying the tumor-suppressive activity of S

173 st time, the investigation of the structural mechanisms underlying the affinity maturation process in

174 However, the mechanisms underlying the anorexigenic effects of oxytoc

175 However, the mechanisms underlying the antidepressant actions of GLYX

176 tions of GLYX-13 to further characterize the mechanisms underlying the antidepressant actions of this

177 The molecular mechanisms underlying the antineoplastic properties of m

178 specificity, and therapy tailored to address mechanisms underlying the arrhythmia.

179 In this study, we aimed to reveal the mechanisms underlying the behavioral action of NPS, and

180 ng evidence, incomplete understanding of the mechanisms underlying the beneficial effects of exercise

181 lic pathways, providing new insight into the mechanisms underlying the beneficial metabolic effects i

182 Recent progress in deciphering the mechanisms underlying the concepts of tumor immunosurvei

183 lavinylation of Complex II homologs, but the mechanisms underlying the covalent attachment of FAD rem

184 However, the mechanisms underlying the critical weight have not been

185 The mechanisms underlying the dedifferentiation and lineage

186 However, the mechanisms underlying the development and organization o

187 which are relevant to the neuropathological mechanisms underlying the development of the disease.

188 schizophrenia, although the neurobiological mechanisms underlying the disorder remain largely undefi

189 l of informing future research examining the mechanisms underlying the E/I imbalance hypothesis acros

190 , rodents and humans for over a century, the mechanisms underlying the effects of probiotics on aging

191 an urgent need to investigate the molecular mechanisms underlying the evolution of therapy-induced r

192 provide a new understanding of the molecular mechanisms underlying the extreme adaptation of the weed

193 However, the mechanisms underlying the formation, storage, and expres

194 Although several mechanisms underlying the generation of phenotypic heter

195 While the mechanisms underlying the high-level expression of GATA1

196 nformation is available regarding the common mechanisms underlying the infection of mosquitoes by the

197 essential in this process, but the molecular mechanisms underlying the influence of experience on int

198 Moreover, mechanisms underlying the interactions between inflammat

199 These studies are the first to probe mechanisms underlying the LRH-1-PGC1alpha interaction an

200 Understanding the deformation mechanisms underlying the mechanical behavior of materia

201 However, the molecular mechanisms underlying the microglial response to prion i

202 ant novel insight into the potential disease mechanisms underlying the neurodegenerative consequences

203 dent spontaneous dopamine transients and the mechanisms underlying the origin were examined in the NA

204 d to elucidate clinically relevant molecular mechanisms underlying the pathogenesis of most monogenic

205 -linked networks is required to decipher the mechanisms underlying the pathogenesis of these diseases

206 ere dengue remains unclear, particularly the mechanisms underlying the plasma leakage that results in

207 The mechanisms underlying the progression of diabetes mellit

208 In the search of mechanisms underlying the proresolving actions of MaR1 i

209 e results support and help to understand the mechanisms underlying the rationale of early cART onset.

210 However, molecular mechanisms underlying the regulation of JAK2 have remain

211 The molecular mechanisms underlying the regulation of MCU, in conditio

212 Therefore, understanding the mechanisms underlying the regulation of mitochondrial pr

213 tance in vitamin D metabolism, the molecular mechanisms underlying the regulation of the gene for thi

214 However, the molecular mechanisms underlying the response of macrophages to ele

215 decisions may contribute to deciphering the mechanisms underlying the role of FCSCs in regulating bo

216 However, mechanisms underlying the role of mcroRNAs in glioblasto

217 To understand the mechanisms underlying the spontaneous drive of the brain

218 f this fine regulatory system, the molecular mechanisms underlying the surface dynamics of CaV1.2 are

219 key role for non-mutational drug resistance mechanisms underlying the survival of residual cancer 'p

220 Yet, the mechanisms underlying the synergy of prime-boost strateg

221 Our results characterize the regulatory mechanisms underlying the transcriptional response to on

222 e to rhabdoid tumors and schwannomas but the mechanisms underlying the tumor type specificity are unk

223 Is there a common mechanism underlying their self-organisation?

224 ction and defined the cellular and molecular mechanisms underlying their expansion.

225 in crop improvement, although the molecular mechanisms underlying their functions remain largely unk

226 such as productivity and robustness, but the mechanisms underlying their origin and maintenance remai

227 However, the mechanisms underlying their progression remain ill-defin

228 Cell, Nagaraja et al. dissect the molecular mechanisms underlying therapeutic responses to transcrip

229 To unravel the molecular mechanism underlying these disorders and investigate pos

230 We performed a detailed investigation of the mechanism underlying these dynamics, using X-ray crystal

231 However, the molecular mechanism underlying these electrophysiological changes

232 A lack of understanding of the mechanisms underlying these adverse outcomes limits our

233 However, the mechanisms underlying these alterations have remained un

234 While the mechanisms underlying these associations are unknown, it

235 However the mechanisms underlying these changes are unknown.

236 tia patients, but the molecular and cellular mechanisms underlying these deficits are largely unknown

237 To elucidate the molecular mechanisms underlying these disease phenotypes, we appli

238 iate different patterns of behavior, but the mechanisms underlying these dissociable actions are uncl

239 However, the biochemical mechanisms underlying these double alterations remain un

240 effects of statins on clinical outcomes, the mechanisms underlying these effects remain elusive.

241 However, the mechanisms underlying these effects remain poorly unders

242 However, the molecular mechanisms underlying these findings are poorly understo

243 Irrespective of the exact rates and mechanisms underlying these findings, they illustrate th

244 s unknown how the transcriptional regulatory mechanisms underlying these functions have changed over

245 iome regulates host metabolism, but specific mechanisms underlying these interactions remain poorly u

246 The molecular mechanisms underlying these negative effects on cognitio

247 ardiomyocyte culture system to elucidate the mechanisms underlying these observations.

248 Cellular and molecular mechanisms underlying these persistent changes were dete

249 However, the mechanisms underlying these processes are not completely

250 The mechanism underlying this apparent protective effect war

251 pending time outdoors is protective, but the mechanism underlying this association is poorly understo

252 s than patients with sporadic MPNST, but the mechanism underlying this correlation is not understood.

253 resolved, shedding some light on the efflux mechanism underlying this intriguing system.

254 plant disease resistance, but the molecular mechanism underlying this modulation was not fully under

255 Herein, we decipher the mechanism underlying this phenomenon.

256 However, the mechanism underlying this preference and the subsequent

257 Here we define the mechanism underlying this rearrangement signature.

258 However, the mechanism underlying this resistance remains unclear.

259 The neural circuit mechanism underlying this selectivity is still unclear,

260 To determine the mechanism underlying this sexually dimorphic difference

261 However, the precise mechanism underlying this synergy within NK cell cluster

262 We now analysed the mechanisms underlying this "silent survival" effect.

263 nisms, but the cell signaling and organellar mechanisms underlying this capability are unclear.

264 However, the mechanisms underlying this disinhibition diverge signifi

265 Despite growing concern, the mechanisms underlying this extensive HGT remain poorly u

266 re, we characterize neural and computational mechanisms underlying this form of social influence.

267 Yet the developmental mechanisms underlying this fundamental mode of organisat

268 The mechanisms underlying this increased risk are not known.

269 directed to the complex and often redundant mechanisms underlying this interaction.

270 ity-related cardiometabolic disease, yet the mechanisms underlying this link remain obscure.

271 The mechanisms underlying this multifunctionality remain poo

272 ain have been developed and point to central mechanisms underlying this phenomena, such as increased

273 do patients with HPV-negative HNSCC, but the mechanisms underlying this phenomenon are unknown.

274 ome of the clearest insights into the neural mechanisms underlying this process have come from studie

275 ine-seeking behavior; however, the molecular mechanisms underlying this process remain largely unknow

276 ties of the moving object, though the neural mechanisms underlying this process remain poorly underst

277 To study the physical mechanisms underlying this process we measured the work

278 Some mechanisms underlying this quantitative signal processin

279 ouse embryos, but the molecular and cellular mechanisms underlying this remain unclear.

280 thma is higher in women than in men, but the mechanisms underlying this sex bias are unknown.

281 We examined two putative genetic mechanisms underlying this sex bias: sex-specific hetero

282 toward major sex differences, the molecular mechanisms underlying this sexual dimorphism remain larg

283 seases known as "synucleinopathies," but the mechanisms underlying this toxicity remain poorly unders

284 The mechanisms underlying this trait are still unclear.

285 ase risk, and the currently known epigenetic mechanisms underlying this transmission.

286 We investigated the mechanisms underlying this viability defect, and demonst

287 ure to rerepress chromatin is one epigenetic mechanism underlying transcriptional memory.

288 renal cancer (ccRCC); however, the molecular mechanisms underlying transformation and the requirement

289 Research has begun to uncover common mechanisms underlying transmission of amyloids, yet how

290 tumoral heterogeneity is proposed as a major mechanism underlying treatment failure of these molecule

291 However, the molecular mechanisms underlying trehalose's effect on taste percep

292 However, the endogenous regulatory mechanisms underlying tumor-associated macrophage differ

293 n hepatocellular carcinoma and establish the mechanism underlying UBE3A-mediated tumorigenesis in thi

294 The mechanisms underlying urothelial formation and maintenan

295 Understanding the molecular mechanisms underlying uterine receptivity will enable th

296 Understanding mechanisms underlying variable metabolic requirements of

297 Are the mechanisms underlying variations in the performance of a

298 The molecular mechanisms underlying vascular inflammation and associat

299 In examining mechanisms underlying Wwox-dependent survival difference

300 The mechanisms underlying Xp reactivation remain enigmatic.