コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 ore domain K(+) (K2P) channel family and are mechanosensitive.
2 dynamic range neurons that were exclusively mechanosensitive.
4 cal theory behind how these proteins display mechanosensitive accumulation has allowed us to predict
6 y, this dermal cell aggregation triggers the mechanosensitive activation of beta-catenin in adjacent
7 fostered by adhesion-mediated signaling, and mechanosensitive activation of RhoA that promotes myosin
8 nvironment interaction models to reveal that mechanosensitive adhesions are necessary to reproduce th
9 r recordings, and the encoding properties of mechanosensitive afferents (serosal, mucosal, muscular,
12 sin II receptor type 1 (AT1 R) is inherently mechanosensitive and initiates this signalling pathway.
13 sitive, itch sensitive, type C low-threshold mechanosensitive and nociceptive neurons with markedly d
15 he articular cartilage is known to be highly mechanosensitive, and a number of mechanosensing mechani
19 vestigated whether pannexins, which can form mechanosensitive ATP-permeable channels, are present in
22 re, we propose that a class of low-threshold mechanosensitive C fibers that innervate the hairy skin
23 er, Ca(2+) influx at the plasma membrane via mechanosensitive Ca(2+) permeable channels is only media
24 on and actomyosin contractility, but also by mechanosensitive Ca(2+) permeable channels on the plasma
25 evel, selective activation of TRPV4 restored mechanosensitive Ca(2+) signaling as well as the functio
26 functional status of TRPV4, which underlies mechanosensitive Ca(2+) signaling in CD cells, inversely
28 channels function as a critical component of mechanosensitive, Ca(2+)-signaling machinery within the
29 Here, we have shown that the endothelial mechanosensitive cation channel PIEZO1 is required for f
30 s catastrophic Ca(2+) influx mediated by the mechanosensitive cation channel TRPC6, which activates h
31 d functional analyses localized the putative mechanosensitive cation channel TRPV4 to the plasma memb
35 l cells that possess many of the features of mechanosensitive cells and mediate important defense and
39 in alternating magnetic fields can activate mechanosensitive cellular functions or physically destru
40 mechanistic perspectives through which many mechanosensitive cellular processes could be quantitativ
41 ein beta-arrestin have been shown to mediate mechanosensitive cellular signaling, we tested the hypot
44 provide a direct link between pathology and mechanosensitive channel dysfunction in nonsensory cells
45 discuss some future direction on repurposing mechanosensitive channel for mechanical actuation of spa
46 d comparison with MscL, a well-characterized mechanosensitive channel from bacteria that is driven by
47 re domain K(+) channel, was the first animal mechanosensitive channel identified at the molecular lev
48 eveloping a stable sensory chip containing a mechanosensitive channel in a Si/SiO(2) chip with a 3 mu
49 m, and has been shown to encode a functional mechanosensitive channel in all species where it has bee
52 screen to search for compounds targeting the mechanosensitive channel of large conductance (MscL) and
57 termined the conditions for releasing intact mechanosensitive channel of large conductance (MscL) pro
59 ion of MPPNs for two unrelated proteins, the mechanosensitive channel of large conductance and the co
66 stid-localized mechanosensitive ion channels Mechanosensitive Channel of Small Conductance-Like2 (MSL
70 R2456H and R2488Q mutations in PIEZO1 alter mechanosensitive channel regulation, leading to increase
73 ew insights into the quantitative biology of mechanosensitive channels and emphasizes the need for ca
76 In prokaryotic cells, a direct gating of mechanosensitive channels by membrane tension was clearl
78 Furthermore, our findings suggest a role for mechanosensitive channels in bacterial calcium regulatio
79 in the mammalian auditory system depends on mechanosensitive channels in the hair bundles that proje
80 e Drosophila S2 cell line also gives rise to mechanosensitive channels in which ion selectivity can b
83 lipid" principle established for prokaryotic mechanosensitive channels MscL and MscS to these eukaryo
84 of MJF465 Escherichia coli strain (devoid of mechanosensitive channels MscL, MscS, and MscK), or on p
86 ts the possibility for specific targeting of mechanosensitive channels of pathogens by therapeutic dr
91 iron oxide magnetite (Fe3O4) are coupled to mechanosensitive channels that elicit neuronal activity
92 s, TRPA1 and TRPV4 are emerging as candidate mechanosensitive channels that play a pivotal role in in
93 ecialized protein/lipid subdomains enclosing mechanosensitive channels to open with localized tension
94 essential elements such as water permeation, mechanosensitive channels, active ion pumps, and active
95 ductance, which serves as a model system for mechanosensitive channels, has previously been crystalli
105 Furthermore, we found that the neurite is a mechanosensitive compartment that becomes softer and ado
106 results indicate that the PECAM-1.Galphaq/11 mechanosensitive complex contains an endogenous heparan
107 shape results from force balance and FAs are mechanosensitive complexes transmitting tension from the
108 ire of behaviors, including light avoidance, mechanosensitive contraction, food selection, and even t
109 ess three potential activating mechanisms at mechanosensitive crosslinks as inputs to a mixture model
110 on by drugs or molecular knockdown decreases mechanosensitive currents, serotonin release and downstr
112 e this system by showing that it can support mechanosensitive differentiation of mesenchymal stem cel
116 g under fluid shear induces unfolding of the mechanosensitive domain in GPIb-IX, which may possibly c
118 nd enabled localization of this quasi-stable mechanosensitive domain of approximately 60 residues bet
119 that most large-diameter proprioceptive and mechanosensitive DRG neurons expressed maternal Ube3a an
120 chanism of signaling that may quickly couple mechanosensitive elements in crowded biological membrane
123 known as P21-activated kinase (PAK), and the mechanosensitive factor, Yes-associated protein 1 (YAP-1
125 ograde flow and myosin II to the ECM through mechanosensitive focal adhesion proteins that are collec
126 y kinases to adhesion complexes and impaired mechanosensitive, force-induced Rho signaling, and rigid
127 MscL, opens a wide pore, which accounts for mechanosensitive gating due to in-plane area expansion.
130 hypermethylation within the promoters of 11 mechanosensitive genes and that 5Aza treatment restored
131 therosclerosis by altering the expression of mechanosensitive genes in the arterial endothelium.
136 air cell is mediated by displacements of its mechanosensitive hair bundle which protrudes from the ap
138 maintaining the structural integrity of the mechanosensitive hair bundles formed by the stereocilia.
139 ells exhibit functional properties of native mechanosensitive hair cells and form specialized synapse
142 ere we investigate the potential to generate mechanosensitive hair cells from mouse embryonic stem ce
148 lular matrix and cell adhesion molecules, to mechanosensitive intracellular structures that regulate
150 ssure-induced secretion was inhibited by the mechanosensitive ion channel antagonists gadolinium, rut
152 families identified mutations in piezo-type mechanosensitive ion channel component 2 (PIEZO2) in eac
153 a synthetic small molecule that activates a mechanosensitive ion channel involved in a blood disorde
155 es the translation of mechanical energy into mechanosensitive ion channel opening, thereby generating
157 study, we show, for the first time, that the mechanosensitive ion channel Piezo2 is specifically expr
158 esults of the present study suggest that the mechanosensitive ion channel Piezo2 is specifically expr
159 bowel GI epithelium selectively express the mechanosensitive ion channel Piezo2, and also that activ
162 nt receptor potential vanilloid 4 (TRPV4), a mechanosensitive ion channel, has been implicated in car
164 the present study we determine the role of a mechanosensitive ion channel, transient receptor potenti
166 ypothesis, we expressed potassium and sodium mechanosensitive ion channels (channels of the two-pore-
167 depends on an influx of K(+) through apical mechanosensitive ion channels and its subsequent removal
173 may mediate cellular discharge by activating mechanosensitive ion channels embedded within cellular m
174 h poration sites for fast ICWs or opening of mechanosensitive ion channels for slow ICWs, which then
176 ondrocyte mechanotransduction by identifying mechanosensitive ion channels functioning at injurious l
178 e auditory and vestibular systems depends on mechanosensitive ion channels in the stereociliary bundl
181 emale gametes, and it has been proposed that mechanosensitive ion channels may sense the resulting me
182 nd illustrate the mechanisms that eukaryotic mechanosensitive ion channels may use to detect and fine
183 functional versions of the plastid-localized mechanosensitive ion channels Mechanosensitive Channel o
184 w that loss of MSL1, a member of a family of mechanosensitive ion channels related to the bacterial c
185 TMC1 and TMC2 proteins are components of the mechanosensitive ion channels that convert mechanical in
188 heart, gut) is mediated by biosensors (like mechanosensitive ion channels), which convert mechanical
189 n principle in the gating cycle of unrelated mechanosensitive ion channels, allowing the coupling of
190 vibrations of the hair-cell bundle activate mechanosensitive ion channels, giving birth to an electr
191 ing that local tissue stiffness, read out by mechanosensitive ion channels, is critically involved in
192 nsory hair cells in the cochlea, by means of mechanosensitive ion channels, the mechano-electrical tr
196 r previous findings suggest that they form a mechanosensitive junctional complex that discriminates b
200 brane interacting TM2-TM3 segment, unique to mechanosensitive K2Ps, against TM4 may further stabilize
202 , all parasites examined lack genes encoding mechanosensitive large-conductance (MscL), mini-conducta
203 hannel Piezo1 is an important determinant of mechanosensitive lineage choice in neural stem cells and
204 that these enzymes are induced in vivo in a mechanosensitive manner provides a clear and sensible un
207 the same spindle pole, they activate another mechanosensitive mechanism to correct the monopolar atta
208 ogue MEC-2 have emerged as key components of mechanosensitive membrane protein signalling complexes.
209 for organ bud formation, demonstrating that mechanosensitive mesenchymal stem cells drive condensati
210 extracellular matrix (ECM) stiffening by the mechanosensitive microRNA-130/301 family, as activated b
211 Here, we hypothesized that dysregulation of mechanosensitive microRNAs (mechanomiRs) in dystrophic s
212 architecture of hair bundles, the arrays of mechanosensitive microvilli-like stereocilia crowning th
213 Here we identify miRNA-712 (miR-712) as a mechanosensitive miRNA upregulated by disturbed flow (d-
214 , correlate with applied force, supporting a mechanosensitive model for vinculin activation in which
215 correlated with applied force, supporting a mechanosensitive model in which forces stabilize vinculi
216 rved repeatedly in the beta-glomerulus only, mechanosensitive modulation of mitral cells and their po
217 main was proposed to constitute an intrinsic mechanosensitive module based on expression of a chimera
218 ha6-integrin is a matrix stiffness-regulated mechanosensitive molecule which confers an invasive fibr
219 longer lever arm (2xELC), producing a highly mechanosensitive motor, could also partially suppress th
221 tiscale continuum model is constructed for a mechanosensitive (MS) channel gated by tension in a lipi
224 ion in interciliary tip links, and anomalous mechanosensitive (MS) channels on the top surface of the
225 ential canonical 1 (TRPC1) subunits assemble mechanosensitive (MS) channels on Xenopus neuronal growt
228 which is compelling for the investigation of mechanosensitive (MS) ion channels, since they are highl
229 by continued regulation through the acutely mechanosensitive myocardin-related transcription factor-
230 This study unveils the self-organizing and mechanosensitive nature of human amniogenesis and establ
231 ry neurons, meaning that the distribution of mechanosensitive nerve endings can be inferred by visual
234 unclear whether Merkel cells are inherently mechanosensitive or whether they can rapidly transmit su
235 e found that selective blockade of adherens, mechanosensitive, or gap junctions effectively inhibited
236 as the other ultrastructural elements in the mechanosensitive organelle were still present at 50% (or
242 a-rich structure-function study on mammalian mechanosensitive Piezo channels reveals a modular protei
246 al spreading depression-evoked activation of mechanosensitive primary afferent meningeal nociceptors
247 ogenesis and increase in fat tissue mass are mechanosensitive processes and hence should be influence
255 force allosterically alters the functions of mechanosensitive proteins within adhesions to elicit bio
258 e regulated by clustering of the endothelial mechanosensitive receptor intercellular adhesion molecul
259 patial and mechanical properties of targeted mechanosensitive receptors in live cells by adjusting th
260 cell through E-cadherin adhesions elicits a mechanosensitive response in neighbor cells that is nece
262 les, together with a significant decrease in mechanosensitive responses, suggesting that a Pcdh15a-Tm
264 ogether, during bladder filling, the bladder mechanosensitive SAAs of Adelta-fibers were attenuated,
265 ere disruption of ordered lipids initiates a mechanosensitive signal for cell growth through mechanic
267 iated immunosuppressive pathways, as well as mechanosensitive signaling cascades that are activated b
269 actile unit of striated muscle and also as a mechanosensitive signaling molecule during cell migratio
272 investigated the characteristics of bladder mechanosensitive single-unit afferent activities (SAAs)
275 c protozoa have genes encoding homologues of mechanosensitive small-conductance (MscS) and K(+)-depen
277 tein complex at the ankle link region of the mechanosensitive stereociliary bundle in hair cells.
279 t is well established that stress fibers are mechanosensitive structures, physical mechanisms by whic
280 hese needs, we developed the first mammalian mechanosensitive synthetic gene network to monitor endot
281 rts that the insulin production of islets is mechanosensitive, these findings open up an exciting new
283 cell-derived cardiomyocytes also prove to be mechanosensitive to matrix and thus generalize the main
287 anslocation and downstream signalling of the mechanosensitive transcription factor megakaryoblastic l
289 /ROCK), actin cytoskeletal remodeling, and a mechanosensitive transcription factor, megakaryoblastic
295 r of formerly 'silent' afferents that became mechanosensitive was increased five fold when the skin w
296 Because P2X4 channels are not intrinsically mechanosensitive, we investigated whether podocytes rele
300 e protein level and nuclear translocation of mechanosensitive Yes-associated protein 1 (YAP1), which
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。