ライフサイエンスコーパス: mechanosensory

1 Here we test mechanosensory abilities of afferent nerves in the pecto

2 at long-term alterations in either visual or mechanosensory activity in vivo resulted in homeostatic

3 normally in animals permanently deprived of mechanosensory activity.

4 High-threshold mechanosensory afferent fibres and small-diameter DRG ne

5 longitudinal tracts and formation of precise mechanosensory afferent innervation to the same CNS regi

6 Animals depend on sensory feedback from mechanosensory afferents for the dynamic control of move

7 Mechanosensory afferents of the massive array of chordot

8 se results with previous findings on primate mechanosensory afferents suggest multiplexed population

9 nic and mesenteric nerves were used to study mechanosensory and chemosensory afferent function in 3-,

10 In chordates, mechanosensory and chemosensory neurons of the periphera

11 neages, the development and evolution of the mechanosensory and electrosensory components of the late

12 Eel's exhibit 'sensory conflict' when mechanosensory and electrosensory cues are separated, st

13 zone (SEZ) of the Drosophila brain processes mechanosensory and gustatory sensory input from sensilla

14 tracing sGPN axons, we identify the antennal mechanosensory and motor center (AMMC) as an immediate h

15 gan neurons from the antenna to the antennal mechanosensory and motor center (AMMC) in the brain.

16 hnston's organ, which innervate the antennal mechanosensory and motor center (AMMC) of the brain.

17 urons that innervate the Drosophila antennal mechanosensory and motor center (AMMC), the first relay

18 mn of the anterior SEZ, creating the antenno-mechanosensory and motor center (AMMC).

19 tricted to the central complex, the antennal mechanosensory and motor center, and the protocerebrum.

20 Here we show that combining mechanosensory and nociceptive cues synergistically enha

21 that this cross-modal signaling between the mechanosensory and olfactory circuits is mediated by neu

22 for known and unknown neuron populations of mechanosensory and pain circuits in the spinal cord.

23 ns that requires the integration of parallel mechanosensory and thermosensory pathways.

24 Insect flight, for example, relies on both mechanosensory and visual pathways.

25 r green alga that is guided by photosensory, mechanosensory, and chemosensory cues.

26 The feedback from mechanosensory-and particularly, proprioceptive-organs m

27 polarization of the forming hair bundle, the mechanosensory antenna of auditory hair cells, depends o

28 ng mechanism based on muscle activity, and a mechanosensory apparatus based on excitable epithelia.

29 Podosomes are multimolecular mechanosensory assemblies that coordinate mesenchymal mi

30 teractions is essential for formation of all mechanosensory-axon branches, the local ligand-induced a

31 d attractive Sema-2b signaling that mediates mechanosensory axonal guidance, fasciculation, and synap

32 Using Caenorhabditis elegans mechanosensory axons and in vivo imaging, we find that,

33 severe disruption of collateral formation of mechanosensory axons.

34 s and that their knock-out causes defects in mechanosensory behaviors related to nose touch and forag

35 red cell-autonomously in glia to orchestrate mechanosensory behaviors.

36 Unlike other molecularly defined mechanosensory C-fibre subtypes, MRGPRB4(+) neurons coul

37 However, the mechanosensory cells and key molecules responsible for s

38 Since mechanosensory cells in connective tissue are surrounded

39 Osteocytes are considered to be the major mechanosensory cells of bone, but how osteocytes in vivo

40 um of lips and olfactory epithelium, and ii) mechanosensory cells of neuromasts belonging to the late

41 Hair cells are the specialized mechanosensory cells of the inner ear that capture audit

42 Hair cells are the mechanosensory cells of the inner ear.

43 lls in the mammalian cochlea are specialized mechanosensory cells that convert sound-induced vibratio

44 emen1 has a negative effect on the number of mechanosensory cells that form in the zebrafish neuromas

45 rosensory cells) and in statocytes (ciliated mechanosensory cells) of C. hemisphaerica, a member of t

46 ligase needed for the ubiquitination of the mechanosensory channel subunit MEC-4.

47 ns in the Transient Receptor Potential (TRP) mechanosensory channel trp-4, a member of the invertebra

48 tor potential vanilloid 4 (TRPV4), a ciliary mechanosensory channel, suggests that OCRL may act throu

49 h response depends solely on cell-autonomous mechanosensory channels, gentle nose touch responses req

50 Mechanosensory chordotonal neurons detect displacements

51 Food modulation is dependent on the mechanosensory cilia of the dopaminergic neurons, indica

52 cence microscopic studies indicated that the mechanosensory cilia of vascular endothelial cells from

53 losely mimic the intricate morphology of the mechanosensory ciliary bundles in biological hair cells.

54 fd3F, is required for specialization of the mechanosensory cilium of chordotonal (Ch) neurons.

55 nction activity between a chemosensory and a mechanosensory circuit.

56 e worm motor circuit, egg-laying circuit and mechanosensory circuits that have not been possible with

57 gressing hearing loss accompanied by loss of mechanosensory cochlear hair cells, while the endocochle

58 ted and processed in somatotopically aligned mechanosensory columns of the spinal cord dorsal horn un

59 gs therefore suggest that TRPM7 is part of a mechanosensory complex adopted by cancer cells to drive

60 to FSS are mediated in part by a junctional mechanosensory complex consisting of VE-cadherin, PECAM-

61 migration, in allowing PECAM-1 to serve as a mechanosensory complex in endothelial cells, in its abil

62 ted to mitochondria but colocalized with the mechanosensory complex that requires the podocin ortholo

63 VEGFR3 levels, a component of a junctional mechanosensory complex, mediate these differences.

64 ntify as another component of the junctional mechanosensory complex.

65 ll, which we show contains a high density of mechanosensory corpuscles innervated by functional rapid

66 helia and, surprisingly, short cilia form in mechanosensory cristae even in the absence of kif3a In c

67 ry cues are separated, striking first toward mechanosensory cues and later toward conductors.

68 ing both coupled motion, in which visual and mechanosensory cues follow the same motion trajectory, a

69 llows independent presentation of visual and mechanosensory cues.

70 gical shear stress induces unfolding of this mechanosensory domain (MSD) on the platelet surface.

71 Specific mutation of the putative PilY1 mechanosensory domain is sufficient to induce virulence

72 the peripheral sensory terminals of primary mechanosensory dorsal root ganglion cells, so the presen

73 hway in peritumoural stromal remodelling and mechanosensory-driven activation of PSCs, and further su

74 3 in peripheral somatosensory neurons causes mechanosensory dysfunction through loss of GABAA recepto

75 lY1 and functional type IV pili are required mechanosensory elements.

76 work models representing sequential steps of mechanosensory encoding: skin displacement at touch rece

77 air follicle type is a functionally distinct mechanosensory end organ.

78 ons are conveyed by distinct combinations of mechanosensory end organs and the low-threshold mechanor

79 les, guard, awl/auchene and zigzag, serve as mechanosensory end organs.

80 ls between its operation in the two types of mechanosensory endings.

81 responsiveness of the broad class of primary mechanosensory endings.

82 to the formation of planar cell polarity in mechanosensory epithelia.

83 tion-based protrusion requires an additional mechanosensory feedback cascade that indirectly links me

84 We show that mechanosensory feedback enhances the recruitment of moto

85 circuit diagram enabling speed modulation by mechanosensory feedback in the vertebrate spinal cord.

86 these results suggest that NLP-12 mediates a mechanosensory feedback loop that couples muscle contrac

87 Here we investigate how mechanosensory feedback shapes active locomotion in a ge

88 exes in the spinal cord, the contribution of mechanosensory feedback to active locomotion and the nat

89 th the hypothesis that flying Drosophila use mechanosensory feedback to detect changes in the wing in

90 est studied in Dipteran flies in which rapid mechanosensory feedback to wing motor system is provided

91 ly on limb mechanics but also on appropriate mechanosensory feedback.

92 s from the lateral ocelli include a tract of mechanosensory fibers originating in the antennae.

93 ffolding protein that is required for normal mechanosensory function in hair cells.

94 echanism for regeneration and maintenance of mechanosensory function in postmitotic auditory hair cel

95 m maintenance of the staircase structure and mechanosensory function of auditory hair bundles.

96 is required for stereocilia maintenance and mechanosensory function of the hair bundle.

97 Colonic and jejunal afferent mechanosensory function was attenuated with age and thes

98 Colonic age-related loss of mechanosensory function was more pronounced in high-thre

99 cular immunopathology and maintained corneal mechanosensory function.

100 onal organs perform proprioceptive and other mechanosensory functions in insects and crustaceans.

101 y structural, signaling, osmoregulatory, and mechanosensory functions within the retina, is mediated

102 The mechanisms underlying mechanosensory hair bundle formation in auditory sensory

103 ling as well as its function during cochlear mechanosensory hair cell development had yet to be ident

104 line makes it a powerful model for studying mechanosensory hair cell regeneration.

105 ans, distributed in fields flanking lines of mechanosensory hair cell-containing neuromasts that dete

106 ion of specific innervation patterns between mechanosensory hair cells (HCs) and afferent spiral gang

107 Mechanosensory hair cells (HCs) are the primary receptor

108 undle (hair bundle) on the apical surface of mechanosensory hair cells (HCs) dictates the direction i

109 Mechanosensory hair cells (HCs) residing in the inner ea

110 The inner ear utricle requires mechanosensory hair cells (HCs) to detect linear acceler

111 s neuromasts - small sense organs containing mechanosensory hair cells - distributed in characteristi

112 genes involved in the differentiation of the mechanosensory hair cells and the neurons innervating th

113 epithelium houses two major types of cells, mechanosensory hair cells and underlying supporting cell

114 Mechanosensory hair cells are the receptor cells of hear

115 Mechanosensory hair cells are vulnerable to environmenta

116 is initiated at auditory sense organs, where mechanosensory hair cells convert sound-induced vibratio

117 lecules or drugs that can protect or restore mechanosensory hair cells has been hampered by limited c

118 s most commonly caused by the destruction of mechanosensory hair cells in the ear.

119 ween olivocochlear (OC) neurons and cochlear mechanosensory hair cells is cholinergic, fast, and inhi

120 Individual tones then stimulate mechanosensory hair cells located at different positions

121 und, motion, and balance is mediated through mechanosensory hair cells located within the inner ear.

122 The mechanosensory hair cells of many auditory receptor orga

123 vels of reactive oxygen species (ROS) within mechanosensory hair cells of the inner ear that have bee

124 enetically encoded Ca(2+) indicator GCaMP in mechanosensory hair cells of the lateral line.

125 Compound 90 protects mechanosensory hair cells with HC50 of 120 nM and demons

126 s, which stems primarily from the failure of mechanosensory hair cells, changes the traveling waves t

127 side antibiotics, both of which are toxic to mechanosensory hair cells, the receptor cells of the inn

128 killing of proximal tubule kidney cells and mechanosensory hair cells, though the mechanisms underly

129 fluorescently labeled AGs in live zebrafish mechanosensory hair cells.

130 lex sounds into tones that are transduced by mechanosensory hair cells.

131 hat several aspects of the global pattern of mechanosensory hairs can be predicted with considerable

132 is covered with between 500 to 750 filiform mechanosensory hairs.

133 utative electric field sensors: antennae and mechanosensory hairs.

134 astrocytic GABA(B)R1/2 signaling suppressed mechanosensory-induced seizure activity in mutants with

135 bridge, all of which receive both visual and mechanosensory information from protocerebral centers.

136 t they are capable of integrating visual and mechanosensory information to direct their arm movements

137 how central circuits integrate and transform mechanosensory information to guide locomotion.

138 Hearing relies on the mechanosensory inner and outer hair cells (OHCs) of the

139 We further show that neurons integrating mechanosensory input facilitate primary nociceptive outp

140 Notably, integration of mechanosensory input from innocuous and nociceptive sens

141 of hydrodynamic forces, contact forces, and mechanosensory input to the interactions among individua

142 In contrast, in the absence of mechanosensory input, FLP-20 signaling is reduced, synap

143 rlying development of MSI between visual and mechanosensory inputs in the optic tectum of Xenopus tad

144 Despite the convergence of nociceptive and mechanosensory inputs on common second-order neurons (SO

145 he subcellular segregation of the visual and mechanosensory inputs to specific regions of tectal neur

146 are governed by combined visual and antennal mechanosensory inputs.

147 Finally, pharmacological inhibition of the mechanosensory ion channel phenocopies the result of gen

148 Deficiency of the mechanosensory ion channel PPK1 gene or RNAi knockdown o

149 le in regulating feeding through specialized mechanosensory ion channels in Drosophila.

150 es the first molecular genetic evidence that mechanosensory ion channels in the enteric neurons are i

151 for example, the axonal projections from the mechanosensory lateral line organize a somatotopic neura

152 Specifically, we show that fish use their mechanosensory lateral line to first sense the curl (or

153 In contrast, the eight mechanosensory lateral lines running over the head surfa

154 ts DELM-1 and DELM-2 (degenerin-like channel mechanosensory linked-1 and degenerin-like channel mecha

155 osensory linked-1 and degenerin-like channel mechanosensory linked-2) are expressed in glia associate

156 onal and molecular mechanisms that translate mechanosensory loss into improved olfactory acuity.

157 ypothesis that N-cadherin is part of a novel mechanosensory mechanism in VSMCs and plays an active ro

158 ) of guard/awl/auchene hair follicles and by mechanosensory Merkel cells in the touch domes of guard

159 indbrain circuitry confirmed that visual and mechanosensory modalities share the same premotor output

160 nical sensing in vivo and, if they do, which mechanosensory modalities they mediate.

161 Compared with mechanosensory modalities, however, vision requires a lo

162 motor programs, similar to those elicited by mechanosensory modalities.

163 sects rely on feedback from their visual and mechanosensory modalities.

164 e apply our nanospring to human myosin VI, a mechanosensory motor protein, and demonstrate nanometre-

165 To this end, we analyzed in mechanosensory mutants food-dependent locomotion pattern

166 he anamniote lateral line system, comprising mechanosensory neuromasts and electrosensory ampullary o

167 des form both ampullary electroreceptors and mechanosensory neuromasts.

168 ystem of electrosensory ampullary organs and mechanosensory neuromasts.

169 lie mushroom body development and spacing of mechanosensory neuron dendrites, here we report that Dsc

170 In mec-7 mutants, the ALM mechanosensory neuron forms a long ectopic neurite that

171 In Caenorhabditis elegans mechanosensory neuron, axons exhibit robust regenerative

172 kin, begins with activation of low-threshold mechanosensory neurons (LTMRs) that innervate the skin.

173 al classes - motor neurons, interneurons and mechanosensory neurons - controls the mechanics of copul

174 In Drosophila, song is detected by antennal mechanosensory neurons and further processed by second-o

175 rve cord that is activated by stimulation of mechanosensory neurons and inhibits feeding initiation,

176 cifically expressed in particular subsets of mechanosensory neurons and modulate their sensitivity di

177 factors comprises the response properties of mechanosensory neurons and, thus, the neural encoding of

178 e Drosophila aGPCR Latrophilin/dCIRL acts in mechanosensory neurons by modulating ionotropic receptor

179 in age-matched populations, the branching of mechanosensory neurons correlated with decreased respons

180 Cutaneous mechanosensory neurons detect mechanical stimuli that ge

181 nteraction, whereas production of functional mechanosensory neurons does.

182 F receptors (PDFR-1) expressed in peripheral mechanosensory neurons enhanced touch-evoked calcium tra

183 We propose that Kolmer-Agduhr cell-like mechanosensory neurons formed part of the mucociliary so

184 The cuticular mechanosensory neurons had only CsGABArdl and CspHCl2 su

185 Here, we show that different classes of mechanosensory neurons in C. elegans are distinguished b

186 Here, we show that dopaminergic mechanosensory neurons in C. elegans release the neuroho

187 xin as a regulator of synapse maintenance in mechanosensory neurons in C. elegans.

188 e elaboration of "menorah"-like dendrites of mechanosensory neurons in Caenorhabditis elegans.

189 This song is perceived via mechanosensory neurons in the antennal Johnston's organ,

190 s by enhancing the sensitivity of peripheral mechanosensory neurons in the body.

191 tubulin gene cause ectopic axon formation in mechanosensory neurons in vivo.

192 Furthermore, we demonstrate that inputs from mechanosensory neurons increase locomotor speed by prolo

193 ech, activation of non-nociceptive touch (T) mechanosensory neurons induces a heterosynaptic depressi

194 Mechanosensory neurons initially extend wild-type neurit

195 imotor integration, we recorded from primary mechanosensory neurons of awake, head-fixed mice as they

196 prior to axon termination in vivo Using the mechanosensory neurons of C. elegans, we found collapse

197 insect flight control, the identities of the mechanosensory neurons responsible for these functions a

198 ies to a sensory stimulus and is mediated by mechanosensory neurons signaling touch interactions amon

199 The sensation of touch is mediated by mechanosensory neurons that are embedded in skin and rel

200 , is mediated by proprioceptors, specialized mechanosensory neurons that convey information about the

201 nsory microdomains in mammalian skin and the mechanosensory neurons that innervate them.

202 s activated by betaine and functioned in the mechanosensory neurons to maintain basal levels of locom

203 laser injury model in Caenorhabditis elegans mechanosensory neurons to screen 654 conserved genes for

204 ans contain a stereotyped array of different mechanosensory neurons, meaning that the distribution of

205 ssed in another set of embryonically derived mechanosensory neurons, the FLP neurons, but these cells

206 Here, using Caenorhabditis elegans mechanosensory neurons, we address this question.

207 diversity can fully block axon branching in mechanosensory neurons.

208 laments that tether NOMPC to microtubules in mechanosensory neurons.

209 oprioceptive feedback, which is generated by mechanosensory neurons.

210 tion after axotomy of Caenorhabditis elegans mechanosensory neurons.

211 structure and reduced excitability of these mechanosensory neurons.

212 gic motorneurons and axon termination in the mechanosensory neurons.

213 fication of subsets of TrkB-expressing touch/mechanosensory neurons.

214 s in the anteroposterior polarity of the ALM mechanosensory neurons.

215 This effect could be mediated by distinct mechanosensory neurons.

216 togenetic stimulation of the touch receptor (mechanosensory) neurons.

217 Their dendrites ramify in primary antennal-mechanosensory neuropils of the head ganglia.

218 vivo, supporting a role of Piezo proteins in mechanosensory nociception.

219 gets voltage-gated sodium channels on Adelta mechanosensory nociceptors to dampen excitability and th

220 However, evidence of a mechanosensory organ (the coronal organ) employing hair

221 el role for the Wnt signaling pathway during mechanosensory organ formation in zebrafish.

222 Johnston's organ is the largest mechanosensory organ in Drosophila; it analyzes movement

223 ngle bract cell on the proximal side of each mechanosensory organ on the Drosophila leg.

224 ng development and remodeling of a zebrafish mechanosensory organ.

225 a sensory system that comprises clusters of mechanosensory organs called neuromasts (NMs) that are s

226 nt axons converge into individual peripheral mechanosensory organs called neuromasts, which contain h

227 rganized epithelial cells that will form the mechanosensory organs of the posterior lateral line.

228 Thus, proper assembly of multicellular mechanosensory organs requires a double-negative circuit

229 increased size and number of taste buds and mechanosensory organs, and shifts in many behavioural tr

230 t and mechanism of the action of dopamine in mechanosensory organs, such as the inner ear and lateral

231 -rich interface of pII cells of the external mechanosensory organs, where Notch signaling occurs.

232 ecorin) and dentin matrix protein-1 (DMP1, a mechanosensory/osteocyte marker), while osteoblast marke

233 e connexin 43 (Cx43) hemichannel (HC) in the mechanosensory osteocytes is a major portal for the rele

234 ine a complex architecture for the ascending mechanosensory pathway.

235 Defining the role of mechanosensory pathways in cartilage during OA pathogene

236 se findings suggest that aberrant epithelial mechanosensory pathways may contribute to pathologic der

237 We hypothesized that epithelial mechanosensory pathways regulated by keratinocyte-specif

238 arises from a linear summation of visual and mechanosensory pathways.

239 Using the Caenorhabditis elegans mechanosensory PLM neurons, we found that posteriorly en

240 for a range of myosin II-dependent cellular mechanosensory processes.

241 Thus, mechanosensory processing defects contribute to anxiety-

242 better understand biophysical mechanisms of mechanosensory processing, we investigated two cell type

243 ntribute to future progress in understanding mechanosensory processing.

244 aGPCRs have been suggested to possess mechanosensory properties, though their mechanism of act

245 icroarchitecture gives rise to its exquisite mechanosensory properties.

246 may provide design principles for a generic mechanosensory protein machine.

247 to radial F-actin bundles and marked by the mechanosensory protein Vinculin.

248 rotein PIEZO1, a long sought after mammalian mechanosensory protein; GLUT1, the glucose transporter;

249 es for several proteins, PIEZO1, a mammalian mechanosensory protein; GLUT1, the glucose transporter;

250 IN5, LIM1 (for LINEAGE ABNORMAL11, INSULIN1, MECHANOSENSORY PROTEIN3), SORLIP1AT (for SEQUENCES OVERR

251 tor with PDZ-binding motif (TAZ) are related mechanosensory proteins that bind to Smad transcription

252 vertebrates studied can regenerate inner ear mechanosensory receptors (i.e., hair cells), but mammals

253 Hair cells, the mechanosensory receptors of the inner ear, underlie the

254 est subcluster expresses both gustatory- and mechanosensory-related genes, suggesting a novel type of

255 We found that the mechanosensory response in this mutant was reduced by 90

256 responsible for the nearly complete loss of mechanosensory response observed in the mutant fly.

257 ally, disrupting fs(1)h function impairs the mechanosensory response of class III da sensory neurons

258 uced recruitment to the fusion site, and the mechanosensory response of MyoII is amplified by chemica

259 ing cell mounts a Myosin II (MyoII)-mediated mechanosensory response to its invasive fusion partner.

260 ngs indicate that Merkel cells actively tune mechanosensory responses to facilitate high spatio-tempo

261 ons compatible with monosynaptic inputs from mechanosensory Rohon-Beard neurons onto ipsilateral V2a

262 Our data suggest that the nucleus plays a mechanosensory role in inflammation by transducing cell

263 ts with truncated forms of talin confirm the mechanosensory role of the talin R3 subdomain and exclud

264 cterial MS channels, including the alternate mechanosensory roles that they may play in complex micro

265 e, swimming behavior, fin ray stiffness, and mechanosensory sensitivity.

266 ptors and hair cells suggests that accessory mechanosensory signaling molecules define common feature

267 r cells requires tip links that interconnect mechanosensory stereocilia and convey force to yet unide

268 In mice, CIB2 is localized to the mechanosensory stereocilia of inner ear hair cells and t

269 transports protein cargos within developing mechanosensory stereocilia.

270 d the distance embryos swam in response to a mechanosensory stimulus (48 hpf).

271 ion of a discrete stimulus; no other form of mechanosensory stimulus could induce the immobility phen

272 The mechanosensory stimulus of blood flow initiates a comple

273 rform a sequence of the two in response to a mechanosensory stimulus.

274 The touch dome is a highly patterned mechanosensory structure in the epidermis composed of sp

275 zyx-1 mutants lacked PLM mechanosensory synapses as adult animals.

276 tant animals, suggesting that zyx-1 protects mechanosensory synapses from locomotion-induced forces.

277 Whereas removing input from the visual or mechanosensory system alone had little effect on pattern

278 A myosin-II-based mechanosensory system controls cellular contractility an

279 Overall, this mechanosensory system is structured like a control syste

280 We term this mechanosensory system the SCWISh (survival through the C

281 bryonic development to form the lateral line mechanosensory system.

282 exhibit morphological defects in vulnerable mechanosensory systems prior to release from the hatcher

283 In the diverse mechanosensory systems that animals evolved, the wavefor

284 moles and tentacled snakes have exceptional mechanosensory systems that illustrate a number of gener

285 as like the olfactory, photic, and acoustico-mechanosensory systems, perhaps indicating a role for th

286 Additional, presumed mechanosensory terminal axons entering via the labial ne

287 Zic2+;EphA4+ neurons are surrounded by mechanosensory terminals, suggesting innervation by mech

288 Similarly, the mechanosensory 'tip links' are replaced in 5-10 hours af

289 nnervated Gli1-expressing progenitors within mechanosensory touch dome epithelia are highly tumorigen

290 The organ of Corti is the mechanosensory transducing apparatus in the inner ear an

291 ed to support the hypothesis that purinergic mechanosensory transduction can initiate visceral pain i

292 the first report of mutation in a mammalian mechanosensory transduction channel-associated with gene

293 Mechanosensory transduction for senses such as proprioce

294 ly been identified as ion channels mediating mechanosensory transduction in mammalian cells.

295 e of the simplest paradigms for the study of mechanosensory transduction.

296 to study the basic biophysical principles of mechanosensory transduction.

297 expression of genes associated with bladder mechanosensory, transduction and signaling systems inclu

298 -dependent dopamine signaling, including the mechanosensory TRP-4 channel in dopaminergic neurons and

299 lower displacement amplitudes, demonstrating mechanosensory tuning to fin mechanics and a consistent

300 , the skin on the nose is covered with domed mechanosensory units known as an Eimer's organs.