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1 cursor cells (GNP) and a MB cell line, PZp53(MED).
2 o Rituxan-induced apoptosis than Myc(ON)CD20(MED).
3 potential use in male erectile dysfunction (MED).
4 100 mg MED), low (<50 mg MED), or none (0 mg MED).
5 mmatory profile (M1 [F4/80(low) Gr1(+) CD11b(med)]).
6 s no impact on disease severity in mice with MED.
7 mputer simulation to examine the accuracy of MED.
8 pes I-IV patients regardless of skin type or MED.
9 erythema was approximately 60% regardless of MED.
10 stent transmission mode of CCYV by B. tabaci MED.
11 They were deemed crossover to MED.
15 he divergent GATA-type transcription factors MED-1 and MED-2 are encoded by an unlinked, redundant pa
16 he T-box factor gene tbx-35, a target of the MED-1 and MED-2 divergent GATA factors, was previously f
19 ly shown that the binding site recognized by MED-1 is a noncanonical RAGTATAC site that is not expect
20 hIP) assays showed recruitment of AR, SRC-1, Med-1, transcription factor IIB (TFIIB), and polymerase
30 his Mediator complex subunit associates with Med 12, Med13, and cyclin C to form a submodule that is
31 nt GATA-type transcription factors MED-1 and MED-2 are encoded by an unlinked, redundant pair of intr
32 actor gene tbx-35, a target of the MED-1 and MED-2 divergent GATA factors, was previously found to re
34 by Trichopoulou et al (range: 0-9; N Engl J Med 2003;348:2599-608) exhibited the highest average yea
35 nd these cells are tumorigenic, whereas CD29(med)24(-/lo) and CD29(med)24(hi) cells have diminished t
36 origenic, whereas CD29(med)24(-/lo) and CD29(med)24(hi) cells have diminished tumorigenicity or are n
37 of 65 medically managed transplant patients (MED), 30 patients supported with an LVAD, and 5 nonfaili
38 (27+/-17 and 27%, respectively; P<0.03) and MED (58+/-42 and 33%; P<0.05) versus CTRL (88+/-52 and 7
39 r compared with younger patients assigned to MED (79% versus 60% for quartiles 4 and 1, respectively;
40 can result in multiple epiphyseal dysplasia (MED), a disease characterized by delayed and irregular b
41 he kinases, KinD, depends on the lipoprotein Med, a mutant of which has been known to cause a canniba
45 ssigned to medical therapy alone (MED) or to MED and coronary artery bypass graft (CABG) surgery in t
48 MYC oncogene, we predict interaction between MED and FBP1 might also have implications for cancer ini
49 on of the musculoskeletal phenotype of PSACH-MED and is directly relevant to the clinical management
51 cells to selectively deplete subunits of the MED and TFIID complexes to dissect the contribution of e
54 i) metal-enhanced electrochemical detection (MED) and (ii) label-free surface plasmon resonance (SPR)
55 (STR), hippocampus (HC), medulla oblongata (MED) and anterior cingulate (ACNG) and five peripheral t
56 thresholds of two Scn8a mouse mutants, Scn8a(med) and Scn8a(med-jo), to flurothyl- and kainic acid (K
57 s guideline-based antidepressant medication (MED) and were randomly assigned to add-on therapy with c
58 N), 5 glioblastoma (GBM), 6 medulloblastoma (MED), and 5 nontumor brain (NT) control samples obtained
59 normal mammary stem cell markers, CD29(hi)24(med), and these cells are tumorigenic, whereas CD29(med)
60 that a homogeneous electron transfer between Med*+ and chalcone epoxides is facilitated by an electro
61 ormed in 65/602 patients (10.8%) assigned to MED, and 55/610 patients (9.0%) assigned to CABG receive
62 MP1, termed Alaskan, China 1, China 2, Med+, Med-, and NC, have been identified, and individuals can
66 a (PSACH) and multiple epiphyseal dysplasia (MED) are relatively common skeletal dysplasias belonging
71 affected by alanine substitutions in Mad and Med at a subset of basic residues within and flanking he
74 ls were enumerated by flow cytometry as CD45(med+) blood mononuclear cells expressing CD34, with addi
77 tural modeling and analysis at http://theory.med.buffalo.edu: THUMBUP, UMDHMM(TMHP) and TUPS, predict
78 Here, we investigated the in vivo role of MED by generating a conditional null mice model in which
79 Finally, we report that overproduction of Med bypassed the dominant negative effect on transcripti
80 region for 2 hours 3 times a day), medicine (MED; carvedilol therapy at 12.5 mg PO BID), or control (
82 was previously observed in a murine model of MED caused by a Matn3 V194D mutation, some mutant protei
83 CD11b(high)]) and proresolving (Mres [F4/80(med) CD11b(low)]) phenotypes, without changing the numbe
87 days, confirming the M2 features of the MGL1(med)/CD11c(+) eATMPhi transcriptional profile and implic
89 ructure-associated MGL1(-)/CD11c(+) and MGL1(med)/CD11c(+) eATMPhis were identified after 8 weeks of
90 h the most immature subset (Oct4(hi)/CD44(hi/med)/CD24(-/+)) demonstrating chemoresistance, dormancy,
91 ating cells (TICs) that copurify with a CD24(med)CD49f(hi) population from premalignant ErbB2-express
95 ion is the thymus, where a few TCRgammadelta(med) cells can be induced to TCRgammadelta(hi) but only
97 ing igf2 signaling inhibited growth of PZp53(MED) cells, implicating igf2 as a potential clinical tar
98 and promoters and of MYC regulated ccnd2, 23 med complex components, and MYC regulated cell survival
110 be a novel mechanism whereby CD11c(hi)MHC II(med) DCs regulate the re-establishment of vascular quies
111 ar expansion, CD11c(hi)MHC class II (MHC II)(med) dendritic cells (DCs) accumulate later, and their s
113 S is freely available at http://www.genetics.med.ed.ac.uk/suspects/ SUPPLEMENTARY INFORMATION: A quic
114 h format is available at http://www.genetics.med.ed.ac.uk/suspects/help.shtml and Excel spreadsheets
116 ranscriptional coactivator complex Mediator (MED) facilitates transcription of nuclear hormone recept
121 nts the concept of metal-enhanced detection (MED) for the determination of DNA-DNA reactions and pres
124 both maternal and zygotic activities of the med genes act to specify endoderm, defects in endoderm s
126 different across the spectrum of age in the MED group (53% versus 49% for quartiles 4 and 1, respect
131 nt a web-server called PseAAC at http://chou.med.harvard.edu/bioinf/PseAA/, by which users can genera
142 , we show that deletion or overproduction of Med impaired or enhanced, respectively, biofilm formatio
144 ssociated with lower mortality compared with MED in per-protocol and several time-dependent analyses
145 amenable to CABG were randomized to CABG or MED in the STICH trial (Surgical Treatment for Ischemic
146 diovascular hospitalization with CABG versus MED in younger compared with older patients (Pinteractio
147 V1.6 through a naturally occurring mutation (med) in mouse peritoneal macrophages inhibited podosome
148 icacy of CABG compared with medical therapy (MED) in patients with heart failure caused by ischemic c
152 i)/CD16(neg) [classical], CD14(+ or hi)/CD16(med) [intermediate], and CD14(neg)/CD16(hi) [nonclassica
156 uch disorder, multiple epiphyseal dysplasia (MED), is characterized by mild dwarfism and early-onset
157 us of brain slices from Scn8a mutant mice of med(J) type, in which there is greatly reduced spontaneo
160 wo Scn8a mouse mutants, Scn8a(med) and Scn8a(med-jo), to flurothyl- and kainic acid (KA)-induced seiz
162 lurothyl-induced seizures, Scn1a(+/-); Scn8a(med-jo/+) mice displayed thresholds that were comparable
165 ion in waist circumference was higher in the MED/LC group (-6.9 +/- 6.6 cm) than in the LF diet group
166 IPF volume had reduced twice as much in the MED/LC group compared with the LF group [-37 +/- 26.2 mL
167 sus -11.5% for the MED/LC; P<0.001), and the MED/LC group decreased reported carbohydrates intake (-3
169 e compared a Mediterranean/low-carbohydrate (MED/LC) diet plus 28 g walnuts/d with a calorically equa
170 c low-fat or Mediterranean/low-carbohydrate (MED/LC) diet+28 g walnuts/day with/without added moderat
171 ted fat intake (-21.0% versus -11.5% for the MED/LC; P<0.001), and the MED/LC group decreased reporte
175 ls isolated from the mediastinal lymph node (med-LN) of aged animals exhibited increased cardiotropis
179 s of LMP1, termed Alaskan, China 1, China 2, Med+, Med-, and NC, have been identified, and individual
180 s and peripheral myelinated axons from Scn8a(med/med) mice, which lack functional Na(V)1.6, no effect
184 We categorized dosages as large (>/=100 mg MED), moderate (50 to <100 mg MED), low (<50 mg MED), or
185 PC were enumerated by flow cytometry as CD45(med+) mononuclear cells expressing CD34 and subsets coex
188 st this possibility, we recorded from GCs of med (Na(v)1.6-null) and wild-type mice during postnatal
189 Our data suggest the key target of the Psi/MED network in controlling developmentally regulated tis
194 vity in U87MG mouse xenografts, achieving an MED of 1.5 mg/kg, following weekly intravenous dosing.
195 ciaries with a prescription yielding a daily MED of more than 120 mg did not decline after adoption o
196 ibers; 5% had prescriptions yielding a daily MED of more than 120 mg in any calendar quarter; and 0.3
197 s yielding a daily morphine-equivalent dose (MED) of more than 120 mg, and treatment for nonfatal pre
198 utcome was daily morphine-equivalent dosage (MED) of opioids dispensed from 60 days before to up to 7
203 wer 5-year mortality than those who received MED only (25% vs 42%; hazard ratio, 0.50; 95% confidence
206 randomly assigned to medical therapy alone (MED) or to MED and coronary artery bypass graft (CABG) s
209 We hypothesize that the myopathy in PSACH-MED originates from an underlying tendon and ligament pa
210 northward and eastward future expansions of MED over both the Euro-Mediterranean and western North A
215 or-RNA polymerase II pre-initiation complex (Med-PIC) was assembled and analyzed by cryo-electron mic
217 using multiple enzymes for sample digestion (MED), primarily an increase of sequence coverage, have b
219 INTERPRETATION: Results from SPYRAL HTN-OFF MED provide biological proof of principle for the blood-
223 was milder than that reported previously in med Purkinje neurons, which prompted us to look for diff
224 erns, these define three distinct classes of MED-regulated genes: MS-specific, E-specific, and E plus
227 ession data from only 30 conditions and that MED results are robust to the existence of unknown occur
229 a metal-enhanced electrochemical detection (MED) sensor, which relied on the redox properties of a s
230 fates in Caenorhabditis, we have identified med sequence homologs in the related nematodes C. briggs
231 y searching the genome for clusters of these MED sites, we have identified 19 candidate MED targets.
232 ce of Med impaired and the overproduction of Med stimulated the transcription of two operons (sdp and
233 pathway, while reduction of Med15 levels, a MED subunit in the tail domain, suppressed the Nodal sig
236 10, reduction of Med12 and Med13 levels, two MED subunits in the regulatory domain, led to an enhance
238 Molecular structure analysis of purified Med-T and Med-T/TFIIH complexes by electron microscopy r
239 mplexes by electron microscopy revealed that Med-T corresponds to the mediator head module of higher
240 IIH-associated protein complex in T. brucei (Med-T) consisting of nine subunits whose amino acid sequ
241 lar structure analysis of purified Med-T and Med-T/TFIIH complexes by electron microscopy revealed th
244 and instantaneous firing rates were lower in med than in wild-type GCs, demonstrating that Na(v)1.6 c
245 the Annals of Internal Medicine (Ann Intern Med), the Annals of Surgery (Ann Surg), Obstetrics & Gyn
246 1.0% (mean, 8.8%) tumor cells are CD29(hi)24(med); these populations significantly increase to 16.5%
249 specification in the absence of the SKN-1-->MED transcriptional input, accounting for the impenetran
250 We demonstrate by in situ hybridization that med transcripts accumulate both in the EMS cell and in t
251 -) embryos made by mothers in which germline med transcripts have been abrogated by transgene cosuppr
255 ublicly available at: http://brainarray.mbni.med.umich.edu/brainarray/datamining/MarkerInfoFinder.
259 rce code is available at http://guanlab.ccmb.med.umich.edu/DREAM/code.html and as supplementary file
268 tAlleles can be obtained from bioinformatics.med.utah.edu/~alun, which also has more information on i
270 o similar extents, the Alaskan, China 1, and Med+ variants had limited binding to the E3 ubiquitin li
271 eased mast cells in the medial intralaminar (Med), ventral posterior (VP) and posterior (Po) nuclei.
274 heteroarenes mediated by a triarylimidazole (Med) was investigated by cyclic voltammetry (CV) and con
276 il in the deep Eastern Mediterranean Sea (E. Med.) water column and to minimize potential bias associ
277 75 are available at http://bioinformaticsprb.med.wayne.edu and http://people.cs.clemson.edu/ approxim
279 ckage available at: http://bioinformaticsprb.med.wayne.edu/PADOG/or http://www.bioconductor.org.
281 hanisms that underpin the pathophysiology of MED we generated a murine model of epiphyseal dysplasia
283 s how and why the geographic distribution of MED will change based on the latest-available climate pr
284 With these understandings, judicious use of MED will likely provide useful information about eukaryo
285 start with 70% of the minimal erythema dose (MED) with 20% increments at each treatment thereafter.
286 s were maintained on multi-electrode dishes (MED) with an 8x8 array of electrodes and examined for ph
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