ライフサイエンスコーパス: medaka

1 (Centroptilum triangulifer), fish (Japanese medaka)).

2 mutants to investigate gonadal dysgenesis in medaka.

3 ution, efflux rate, and maternal transfer in medaka.

4 erivate was confirmed in vivo in spiggin-gfp Medaka.

5 n and choriogenin gene induction in the male medaka.

6 eta, generally recapitulated observations in medaka.

7 bility is not shared by another teleost, the medaka.

8 was recently identified in another teleost, Medaka.

9 We investigated in medaka a possible meiotic function of RA during the embr

10 Aequorin-injected eggs of the medaka (a fresh water fish) show an explosive rise in fr

11 elayed and reduced macrophage recruitment in medaka, along with delayed neutrophil clearance.

12 The medaka and fugu TRs, when assembled with their telomeras

13 t/PK on telomerase reverse transcriptase for medaka and human is modeled based on the cryoEM structur

14 function as Delta4 desaturases of Fads2 from medaka and Nile tilapia.

15 edgehog; the fish genomes of stickleback and medaka and the second example of the genomes of the sea

16 Our systematic analysis of medaka and zebrafish demonstrates that in fish, the morp

17 lomerulus are astoundingly different between medaka and zebrafish.

18 d for the Sec24d-deficient fish mutants vbi (medaka) and bulldog (zebrafish).

19 he mechanism between sex reversal and DMY in medaka, and suggested that XY(DMY-) medaka was a novel m

20 ved syntenies between catfish and zebrafish, medaka, and Tetraodon were established, but the overall

21 Interestingly, medaka appeared to rapidly shuttle Se to their eggs dire

22 neuromasts of the posterior lateral line in medaka are composed of two independent life-long lineage

23 utation produces Japanese gold-colored fish, medaka b, maps to the mouse underwhite locus.

24 (fertility, fecundity) by 7.3-57.4% in adult medaka breeding pairs, with hindrance of SSC development

25 meiosis induction and gametogenesis in adult medaka but contrary to common expectations, not for init

26 hat retain anterior pharyngeal teeth such as medaka but that medaka do not express the aldh1a2 RA-syn

27 rative genome analysis between zebrafish and medaka, common carp, grass carp, and goldfish to study t

28 ve 5-iodouridines were incorporated into the medaka CR4/5 RNA fragment and UV cross-linked to the med

29 ior pharyngeal teeth such as medaka but that medaka do not express the aldh1a2 RA-synthesizing enzyme

30 s, acid alpha-glucosidase from zebrafish and medaka does not appear to be modified with mannose 6-pho

31 conclude that the fertilization wave in the medaka egg is propagated by calcium-stimulated calcium r

32 sis of glycosidase activity in zebrafish and medaka eggs revealed selective deposition of enzymes req

33 ar and central nervous systems in developing medaka embryo through SNC-induced differential expressio

34 We treated medaka embryos at 12 h post fertilization with 50 muM Se

35 o hatch and depleted glutathione in Japanese medaka embryos without affecting Se accumulation.

36 stimulating Toll-like receptor signaling in medaka enhanced immune cell dynamics and promoted neovas

37 ociated with differential activities of each medaka ER.

38 ively with preferential binding affinity for medaka ERbeta subtypes, which are highly expressed in ma

39 Results indicate that all three medaka ERs (mERs) are capable of initiating transactivat

40 In the in vivo bioassays, medaka exposed to individual pesticides or to AP/APEO al

41 This study uses nPbO2(s) and medaka fish (Oryzias latipes) as surrogates to investiga

42 ecently, haploid pluripotent cell lines from medaka fish (Oryzias latipes) have also been established

43 Here we report a unique medaka fish (Oryzias latipes) mutant, hirame (hir), whic

44 Larvae of medaka fish (Oryzias latipes) underwent 3-14 days' aqueo

45 In vivo injection, in medaka fish (Oryzias latipes), of the mutated miR-204 ca

46 unction of the orthologous genes in mice and medaka fish and further expands our understanding of gen

47 rally active DNA transposon derived from the medaka fish called Tol2, as an alternative system for hi

48 Finally, knockdown assays in medaka fish demonstrated that miR-204 is necessary for n

49 Using medaka fish embryo model, the toxic effects and correspo

50 x3.2 distribution in distinct domains of the medaka fish forebrain.

51 Previously, knock-out of Arhgef18 in the medaka fish has been shown to cause larval lethality whi

52 anipulating the expression of miR-204 in the Medaka fish model system.

53 own to cause laterality defects in mouse and medaka fish models.

54 Here, we provide documentation that GM male medaka fish modified with salmon growth hormone possess

55 The Japanese medaka fish Oryzias latipes has an XX/XY sex-determinati

56 acterization of the regulatory region of the medaka fish Six3.2 ortholog and of a time/cost-effective

57 The medaka fish was chosen as the experimental aquatic model

58 Two teleost fish, (zebrafish and medaka fish) have each been shown to possess only a sing

59 ated subdomains in Oryzias latipes (Japanese medaka fish), which has the smallest vertebrate TR ident

60 g morpholino-mediated ablation of Slc38a8 in medaka fish, we confirmed that pigmentation is unaffecte

61 of DMY as the male sex-determination gene in medaka fish.

62 bility processes and toxicity of nPbO2(s) in medaka from the aqueous particle behavior under environm

63 es, per1a and per1b, one per2, and one per3; medaka, fugu, and tetraodon each have two per2 genes, pe

64 of identity >99.8% and length 4682 bp in the medaka genome.

65 ning pf linked to the regulatory sequence of medaka germ gene vasa and generated transgenic fish with

66 termine male development in sticklebacks and medaka have revealed several features associated with in

67 We have cloned a medaka homolog of the human retinoblastoma (Rb) suscepti

68 putative regulatory regions of the fugu and medaka Hoxa2(a) and -(b) genes and assayed their activit

69 stosterone at 58.8 mug/L in vivo in Japanese medaka in a 21 day exposure.

70 Medaka is an ideal model for sex determination and sex r

71 sion of these two chemokine receptors in the medaka juvenile thymus defined two spatially distinct su

72 nal transgenesis with spg1-gfp led to stable medaka lines.

73 o estrogenic metabolites was not observed in medaka liver microsomes and cytochrome P450 was not indu

74 subtypes, which are highly expressed in male medaka liver prior to estrogen exposure.

75 utation in liver tissue of lambda transgenic medaka may be mediated through compromised liver functio

76 ional alterations characterized suggest that medaka may provide a novel model and, thus, provide addi

77 imilar to human P2ab than predicted, and the medaka minimal pseudoknot has the same tertiary interact

78 The spg1-gfp medaka model provides a sensitive, specific, and physiol

79 be taken into account in future analyses of medaka mutants with glomerulus defects.

80 GM medaka offspring possess a survival disadvantage relativ

81 Meanwhile, medaka oligo DNA microarray and qRT-PCR were used for ge

82 Larval medaka (Orizias latipes) readily consumed S. coeruleus i

83 productive capacity was assessed in Japanese medaka (Oryzias latipes) after exposure to two concentra

84 nalysis of orthologous genes in the Japanese medaka (Oryzias latipes) and a catfish (Synodontis multi

85 In rapidly dividing blastomeres of medaka (Oryzias latipes) and in somatic cells, SSX2IP kn

86 epigenetic marks (H3K4me3 and H3K27ac) from medaka (Oryzias latipes) and zebrafish (Danio rerio), tw

87 y using the small cyprinodont fish, Japanese medaka (Oryzias latipes) as a model.

88 brates, whereas fugu (Takifugu rubripes) and medaka (Oryzias latipes) have two coparalogous genes [Ho

89 In vivo exposure studies employing Japanese medaka (Oryzias latipes) indicate that low concentration

90 develop a sensitive and specific transgenic medaka (Oryzias latipes) model bearing an androgen respo

91 A full-length cDNA clone of the medaka (Oryzias latipes) p53 tumor suppressor gene was i

92 Adult male Japanese medaka (Oryzias latipes) were exposed to solutions of si

93 ative roles of three ER subtypes in Japanese medaka (Oryzias latipes), using vitellogenin (VTG) I and

94 approximately 30-fold from an inbred strain medaka (Oryzias latipes), we observed that both the sens

95 nvasive live imaging of the entire thymus in medaka (Oryzias latipes).

96 come pathways were evaluated in the Japanese medaka (Oryzias latipes).

97 ll-length CR4/5 domain from the teleost fish medaka (Oryzias latipes).

98 us mykiss) and in vivo studies with Japanese medaka (Oryzias latipes).

99 so appears to induce avoidance behaviours in medaka (Oryzias latipes); but etomidate could provide an

100 ces in length and sequence, the structure of medaka P2ab is more similar to human P2ab than predicted

101 on NMR structure and studied the dynamics of medaka P2ab, and identified all base pairs and tertiary

102 ology between putative functional domains of medaka p53 and p53 genes from other vertebrate taxa incl

103 owed that zebrafish per1a/per1b and fugu and medaka per2a/per2b have asymmetric evolutionary rates, i

104 The medaka Rb cDNA encodes a predicted protein of 909 amino

105 ertebrate Rb sequences demonstrates that the medaka Rb cDNA is highly conserved in regions of functio

106 an pRb recognizes the protein product of the medaka Rb gene, detecting a 105 kDa protein in all tissu

107 gnments with tetraodon, zebrafish, fugu, and medaka resulting in assignments of homology for 199 loci

108 Here, we show that an osx mutation in medaka results in severe bone defects and larval lethali

109 stem cells (NSCs) of embryonic origin in the medaka retina.

110 ing of six MNNG-induced tumors in four adult medaka revealed no mutations within characteristic mutat

111 TE), WT female (WT_F_OV) and XY(DMY-) female medaka (TA_F_OV) gonad libraries.

112 horing a comparative map with the zebrafish, medaka, tetraodon, and fugu genomes.

113 ed from the Y chromosome of the teleost fish medaka that is functionally comparable to the mammalian

114 ctodysplasin-A receptor, in the teleost fish Medaka, that results in a failure of scale formation.

115 t the midline to form a glomerulus, while in medaka the two parts remain unmerged due to the interpos

116 f several fish species, including zebrafish, medaka, threespine stickleback and fugu, the amphibian X

117 transgenic fish model, the lambda transgenic medaka, to evaluate the potential mutagenicity of PFOS i

118 R4/5 RNA fragment and UV cross-linked to the medaka TRBD protein fragment.

119 (1) The glomerular primordium of medaka - unlike the one of zebrafish - exhibits a C-shap

120 comprising 3kb promoter/enhancer regions of medaka VTGI and VTGII genes.

121 d DMY in medaka, and suggested that XY(DMY-) medaka was a novel mutant that is useful for investigati

122 The larvae of medaka were treated with solutions containing nPbO2(s) o

123 First, telomerase from the fish medaka, which extends the same telomeric DNA primer as h

124 haracteristics of the exocytotic wave in the medaka with that in other eggs, particularly in echinode

125 key regulators of eye development in mouse, medaka, Xenopus, and zebrafish.