ライフサイエンスコーパス: mediator

1 equivalent bioelectrode cells with dissolved mediator.

2 Hypertension was set as the mediator.

3 adjustment for TIBC-so iron is not likely a mediator.

4 eeds at rt in the absence of a base or metal mediator.

5 3,3',5,5'-Tetramethylbenzidine (TMB) as the mediator.

6 g that afferent inputs are critical upstream mediators.

7 ytometry and measurements of proinflammatory mediators.

8 and subsequent expression of proinflammatory mediators.

9 ted post-ischemic expression of inflammatory mediators.

10 ified eosinophils as a novel source of these mediators.

11 fferentiation, and production of profibrotic mediators.

12 nappropriate synthesis of proresolving lipid mediators.

13 lammatory cells, along with reduced cytokine mediators.

14 s by directly up-regulating its key cellular mediators.

15 y primed to respond robustly to inflammatory mediators.

16 ) were increased in response to inflammatory mediators.

17 ein upregulated in asthma by type 2 immunity mediators.

18 ssortment of biologically relevant signaling mediators.

19 The proresolving lipid mediator, 15-epi lipoxin A4 (15-epi LXA4), plays a criti

20 dase) with ferrocyanide as electron-transfer mediator, achieving a linear range from 0.05 to 1mM.

21 iation between SBP and mitral regurgitation (mediator-adjusted HR 1.22; CI 1.20, 1.25; p < 0.001).

22 AV-NT mice, the signaling pathways of the CR mediators, AMP-activated protein kinase (AMPK) and sirtu

23 EC expulsion that was coordinated with lipid mediator and cytokine production and lytic IEC death.

24 PB and MLV highly correlated with Cohesin, Mediator and ESC-specific transcription factors.

25 lexes revealed specific interactions between Mediator and the RSC, Arp2/Arp3, CPF, CF 1A and Lsm comp

26 cell subsets by flow cytometry, and soluble mediators and antibodies by ELISA; the percentage of mig

27 by phagosomal cargo, as well as inflammatory mediators and cellular activation affect many aspects of

28 ponse coincides with raised levels of immune mediators and infiltration of immune cells into infected

29 viewed, indicating that SPMs are physiologic mediators and pharmacologic agonists that stimulate reso

30 fatty acid-derived specialized proresolving mediators and proteins, such as annexin A1.

31 MP) and protein kinase A (PKA) are important mediators and regulators of apoptosis.

32 ell-type-specific regulation of inflammation mediators and shedding new light on the role of fibrobla

33 acid epoxides as new mast cell-derived lipid mediators and show that they are produced by PAF-AH2, an

34 However, the array of enzymatic mediators and the exact chemical mechanisms responsible

35 ed a panel of IFN-regulated genes, antiviral mediators and transcriptional regulators.

36 s neurotoxin, gliotoxin, and proinflammatory mediator, and it alters the integrity and cohesion of th

37 ar lavage (BAL) fluid leukocytes, cytokines, mediators, and epithelial cell function for these asthma

38 complement, leukocyte CD11b and inflammatory mediators, and in Wistar rats increased fibrotic overgro

39 xpression of profibrotic and proinflammatory mediators, and increased TRPC6, PKC-alpha, and PKC-beta

40 lar morphology, surface phenotype, secretory mediators, and proliferative responses (referred to as a

41 sponses in clinical parameters, inflammatory mediators, and proportions of individual microbial taxa

42 ging biosupercapacitor based on an optimised mediator- and membrane-free enzymatic glucose/oxygen bio

43 We detail a mediator- and membrane-free enzymatic glucose/oxygen bio

44 tions when repeated measures of exposure and mediator are available and an exposure-mediator interact

45 sed skin expression of the anti-inflammatory mediator arginase-1 (P = 0.005), and a sustained reducti

46 ory/secretory products but few related lipid mediators as established by metabololipidomic analysis.

47 nflammation, RVX-297 reduced proinflammatory mediators assessed in splenic gene expression and serum

48 tive function at age 7-14 years (i.e., joint mediators beta = -0.07, 95% confidence interval: -0.12,

49 lack compared to the white RH, acting as the mediator between implicit prejudice and magnitude of the

50 Inflammatory mediators binding to Toll-Like receptors (TLR) induce an

51 ression, reduced expression of the mitophagy mediators BNIP3 and BNIP3L, and impaired mitophagy.

52 eptors LGR4, LGR5 and LGR6 are Wnt signaling mediators, but their functions in squamous cell carcinom

53 ce the immune benefits expected from omega-3 mediators called resolvins.

54 olded protein response and the pro-apoptotic mediators CamkII and Stat1 was impaired in Trpc3-deficie

55 ved to be driven by gut-derived inflammatory mediators carried via mesenteric lymph (ML).

56 This finding provides a novel context for mediator-catalyzed RPA exchanges during the multistep pr

57 to allergens induces the release of soluble mediators causing allergic symptoms.

58 The multiprotein Mediator coactivator complex functions in large part by

59 entified as a subunit of the transcriptional mediator complex MED25.

60 ein-coding gene SLC3A2 in cis by binding the Mediator complex to facilitate the establishment of enha

61 o subunits of the transcriptional regulatory Mediator complex, MED5a and MED5b, results in an increas

62 rometry of proteins in immunoprecipitates of mediator complexes revealed specific interactions betwee

63 Specifically, specialized proresolving mediators comprise a family of mediators that include ar

64 Targeting NLRP3 inflammasome pathway mediators could thus be developed as therapeutic interve

65 Resolvins, a class of lipid mediators, counteract this effect, representing an attra

66 cribed is particularly suitable for studying mediator-dependent microbial electron transfer processes

67 -A; however, exposure of SCs to inflammatory mediators derived from ZIKV-infected macrophages led to

68 elucidated the metabolic role of JAK2, a key mediator downstream of various cytokines and growth fact

69 nce that versican is a critical inflammatory mediator during poly(I:C)-induced acute lung injury and,

70 Also, AD inflammatory mediators (e.g. MMP12, IL-12/IL-23p40, CXCL9, CCL22, PI3

71 between confounders (e.g., prematurity) and mediators (e.g., use of pacifier).

72 Human acini also secreted inflammatory mediators elevated in acute pancreatitis patients, inclu

73 ulate unmeasured confounding of the exposure-mediator, exposure-outcome, and mediator-outcome relatio

74 a constituent of the eicosanoid inflammatory mediator family of molecules that promote both physiolog

75 es it enhanced the expression of the pro-Th1 mediators Fizz-1 and arginase 1, indicating that it coul

76 identified Prmt1 as a key common downstream mediator for beta-catenin/Hoxa9 functions in LSK-derived

77 i-inflammatory cytokine IL-10 was a critical mediator for PGRN-mediated anti-inflammation in collagen

78 antification (by the peak of current) of the mediators for individual species as well as in an aqueou

79 nd TRIB1 for triglycerides) that were causal mediators for the corresponding traits, as well as examp

80 ed with reduced secretion of proinflammatory mediators from microglia cells, ultimately rescuing neur

81 Our interpretation of these results is that Mediator functions as an assembly factor that facilitate

82 through electron-transfer proteins; or (iii) mediator-generating enzymes detached from cells.

83 c approaches targeting an individual hormone/mediator have yielded somewhat disappointing body weight

84 the electrochemical properties of different mediators (hexacyanoferrate, HCF, riboflavin, RF) were c

85 rol an entire process by acting on a crucial mediator; however, this is a quite exceptional mechanism

86 cing increases expression of proinflammatory mediators; however, the observed response was modest.

87 uggests, the host receptor herpesvirus entry mediator (HVEM) facilitates herpes simplex virus (HSV) e

88 rode in three different charges of the redox mediators (i.e., neutral FcCH2OH, cationic Ru(NH3)6(3+),

89 ated the expression of numerous inflammatory mediators implicated in the TSS-associated cytokine stor

90 as a previously unrecognized chemoresistance mediator in colorectal cancer, thereby establishing the

91 ephrin-B2 (sEphrin-B2) as a new profibrotic mediator in lung and skin fibrosis.

92 ify the CXCL2/MIF-CXCR2 axis as an important mediator in MDSC recruitment and as predictors and poten

93 weight changes, often leading to the hormone/mediator in question being dismissed as a potential obes

94 and might thus have a role as an endogenous mediator in the resolution of inflammation.

95 Here we demonstrate that the choice of redox mediator in these solar cells has a profound influence o

96 (LPS) significantly induced proinflammatory mediators in a dose-dependent manner.

97 he as yet unrevealed action of PFOS on lipid mediators in affecting testicular functions.

98 (EVs) have been recently reported as crucial mediators in cell-to-cell communication in development a

99 ut their crucial participation, likely being mediators in electron transfer, was indicated by specifi

100 to produce cytokines, chemokines, and lipid mediators in response to subsequent TLR stimulation.

101 ce of costimulatory signals and inflammatory mediators in the intestinal mucosa.

102 Pancreatic stellate cells (PSCs) are key mediators in the production of this fibrotic stroma, upo

103 he expression of vasoactive and inflammatory mediators in the vitreous of patients with idiopathic ER

104 Inflammatory mediators include cytokines of the interleukin-1 family,

105 The major inflammatory mediators include IL-1 family members, such as IL-1beta,

106 formation of the most relevant inflammation mediators including proteins and lipids in human fibrobl

107 t-TKA joint, expresses multiple inflammatory mediators, including the monocyte chemoattractant, chemo

108 itated by the Mediator, then acts to relieve Mediator-induced repression to generate an active form o

109 e and mediator are available and an exposure-mediator interaction may exist.

110 could be considered an essential regulatory mediator involved in modulation of neutrophil migration

111 Mediator is a multi-unit molecular complex that plays a

112 ely to benefit patients in whom the targeted mediator is not only expressed but demonstrably driving

113 Interestingly, key autophagic markers and mediators LC3-II, Atg7 and Beclin1 were reduced in Delta

114 The pro-inflammatory mediator leukotriene B4 (LTB4) is implicated in the path

115 These included inflammation initiating mediators leukotriene B4 and prostaglandin E2 and pro-re

116 Herein, we studied bioactive lipid mediator (LM) profiles of tendon-derived stromal cells i

117 , reduced serum immunoglobulins and allergic mediators, lower mast cells and eosinophil counts, lower

118 d secretion of the resistance-inducing lipid mediator, lysophosphatidylcholine(24:1).

119 ory response by targeting microbiota-derived mediators might be a promising therapy against I/R injur

120 moter GATA1 site eliminated LDB1 complex and mediator occupancy and resulted in loss of LCR/beta-glob

121 ls a new biological function for uPA-uPAR as mediator of a neuron-astrocyte cross talk that promotes

122 e identify cytohesin 1 (CYTH1) as a critical mediator of adhesive properties in primary human cord bl

123 tal posterior mesenchyme, where it acts as a mediator of anterior to posterior (AP) patterning, where

124 r and tumor suppressor FOXO3 is an important mediator of apoptosis, but the mechanisms that control i

125 un N-terminal kinase (JNK), and an important mediator of autoimmune and inflammatory responses.

126 intact angiotensin-(1-7) is not the primary mediator of beneficial effects ascribed to the ACE2/angi

127 ical models of sediment bioturbation - a key mediator of biogeochemical cycling - to determine whethe

128 early B-cell factor 2 (EBF2) is an essential mediator of brown adipocyte commitment and terminal diff

129 b as a significant (P=1.3x10(-21)) candidate mediator of CDC-induced Mvarphi polarization, and PKCdel

130 s, we identify the HA genomic segment as the mediator of cell death inhibition.

131 th factor (NGF) has been implicated as a key mediator of chronic pain.

132 factor receptor (EGFR) signaling is a known mediator of colorectal carcinogenesis.

133 o the p19ARF-MDM2-p53 pathway, is a critical mediator of colorectal tumorigenesis following APC loss.

134 NF-kappaB has recently gained attention as a mediator of complex psychiatric phenomena such as stress

135 dings provide evidence that poly GA is a key mediator of cytotoxicity and that cross-talk between DPR

136 n presenting CaMKII as a possible downstream mediator of detrimental beta-AR signaling in HF.

137 me maintenance complex components (MCMs) and mediator of DNA damage checkpoint 1 (MDC1) expression.

138 results illustrate that SIX1 is the central mediator of dorsal mandibular arch identity, thus ensuri

139 st how the traffic jams can act as a unified mediator of downstream pathophysiology.

140 ent SUMOylation of FOXP1 may be an important mediator of early cortical development and neuronal netw

141 e adaptor protein p130Cas/BCAR1 is a crucial mediator of ErbB2 transformation and that its overexpres

142 s lacking FXR1P, demonstrating that p21 is a mediator of FXR1P in aNSCs.

143 E: The sympathetic nervous system is a major mediator of heart function.

144 of organismal metabolism.HDAC3 is a critical mediator of hepatic lipid metabolism and its loss leads

145 tion, cells were incubated with NRG1-beta, a mediator of HER2-HER3 signaling, or A83-01, an inhibitor

146 the extracellular matrix may be an important mediator of HIV-1 interaction with alpha4beta7-expressin

147 enosine monophosphate (cAMP) is an important mediator of hormonal stimulation of cell growth and diff

148 25-hydroxycholesterol (25HC), was a critical mediator of host protection against ZIKV.

149 bitory factor (MIF) to be the most pertinent mediator of increased macrophages.

150 TEMENT: Toll-like receptor 4 (TLR4) is a key mediator of innate immune signaling and has been implica

151 te that adipose Dnmt3a is a novel epigenetic mediator of insulin resistance in vitro and in vivo.

152 ription 3 (STAT3) is a pleiotropic signaling mediator of many cytokines, including interleukin-6 (IL-

153 rrounded by the endoplasmic reticulum, a key mediator of mitochondrial Ca(2+) uptake.

154 m of dynamin-related protein 1 (Drp1), a key mediator of mitochondrial fission.

155 MFN2 encodes mitofusin 2, a membrane-bound mediator of mitochondrial membrane fusion and inter-orga

156 yostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration.

157 Complement activation is a recognised mediator of myocardial ischaemia-reperfusion-injury (IRI

158 actor acetylhydrolase 1B1 (LIS1), a critical mediator of neuronal migration in developing brain, is e

159 ell as how BDNF may function as a downstream mediator of newer pharmacological agents currently under

160 servations identify TGF-beta2 as the crucial mediator of NPC immunomodulation.

161 Insulin resistance is a key mediator of obesity-related cardiometabolic disease, yet

162 the protein phosphatase Shp2 is an important mediator of oligodendrocyte differentiation and myelinat

163 the fly ortholog of mammalian Nova-1/2, as a mediator of Orb2A mRNA processing.

164 onents of axon infrastructure is a potential mediator of pathophysiological damage after demyelinatio

165 ) is a clinically and functionally important mediator of PCa bone and visceral metastases, activating

166 transcription factor CREB3L1 as an essential mediator of PERK's pro-metastatic functions in breast ca

167 and provide evidence of IL-1 signaling as a mediator of post-traumatic astrogliosis and seizure susc

168 togen-inducible gene 6 (Mig-6) is a critical mediator of progesterone receptor (PGR) action in the ut

169 memory B cell responses.IgE is an important mediator of protective immunity as well as allergic reac

170 he process of degradation and is the primary mediator of protein turnover in the cell.

171 cyte chemoattractant protein-1 (MCP-1), is a mediator of PTH's anabolic effects on bone.

172 ntified JAK1/STAT3 activation as a potential mediator of synergistic interactions.

173 Although IFNgamma is the central mediator of the adaptive immune response to pathogens, i

174 ibition of protein translation as a critical mediator of the antileukemic effects of withaferin A and

175 f cFGF23 fragments, probably is an important mediator of the association between ID and mortality.

176 s regulated by NF-E2-related factor 2, a key mediator of the cellular antioxidant response.

177 atients with EoE that has been shown to be a mediator of the disease.

178 particular, thrombin was identified as a key mediator of the effects induced by SW620Exos in target c

179 ish peroxidase and potassium ferrocyanide as mediator of the electron transfer) was adsorbed on the s

180 ats, suggesting that serotonin is a critical mediator of the energy balance impact of GLP-1 receptor

181 ated with nuclear accumulation of YAP, a key mediator of the Hippo pathway.

182 We propose miR-142-3p as a molecular mediator of the IL-1beta-dependent downregulation of the

183 hese results indicate that miR-146a is a key mediator of the renal tubular response to IRI that limit

184 intermediates, NH2OH and NO, necessitating a mediator of the third enzymatic step.

185 oskeleton is a key phosphorylation-dependent mediator of the toxicity of wild-type tau and of all the

186 (IRE1alpha) endoribonuclease (RNase), a key mediator of the UPR, cleaves Xbp1 mRNA to generate a pot

187 s increasingly considered to be a pathologic mediator of these commonly co-occurring diseases.

188 Muscle is emerging as a key mediator of this homeostatic control through consumption

189 system overactivation, and that CD163 is key mediator of this phenomenon.

190 cells identified nitric oxide (NO) as major mediator of this phenotype in PDX and in patient-derived

191 models) laden with whole genomic mtDNA as a mediator of this phenotype.

192 an important role for amygdala function as a mediator of this relationship at a very early age.

193 ntify Phosphoglycerate Mutase 5 (PGAM5) as a mediator of this response.

194 ociated death domain (TRADD) is an essential mediator of TNF receptor signaling, and serves as an ada

195 ctor beta-activated kinase 1 (TAK1) is a key mediator of toll-like receptors and pro-inflammatory cyt

196 , we demonstrate that GA101 is a more potent mediator of trogocytosis than RTX in vitro in both norma

197 We show that Adamts1 is a major mediator of vascular homeostasis, given that genetic hap

198 This study assesses mediators of a more harmonized approach to implementing

199 osomes in postshock mesenteric lymph are key mediators of acute lung injury triggering the macrophage

200 actone-exposed DCs showed that expression of mediators of antigen presentation, including MHC class I

201 IgE antibodies are key mediators of antiparasitic immune responses, but their p

202 Type I interferons (IFNs) are essential mediators of antiviral responses.

203 e I interferons (IFNalpha/beta) are critical mediators of any anti-viral immune response and IFNbeta

204 CD4(+) T cells are central mediators of autoimmune pathology; however, defining the

205 eptide concentrations; and at SLC9A3R1, with mediators of calcium and phosphate signalling.

206 ions in mitochondrial metabolism are the key mediators of cardiac hypertrophic growth.

207 elial dysfunction, all of which are critical mediators of cardiovascular disease.

208 Fibroblasts are powerful mediators of chronic inflammation.

209 also be useful in utilizing the RPE cells as mediators of drug delivery to intracellular targets and

210 Hydroquinones are important mediators of electron transfer reactions in soils with a

211 Identifying such central mediators of epithelial dysfunction using both systems b

212 sion of TK receptors, the phosphorylation of mediators of ERK1/2 and p38 pathways and STAT3 (S727) we

213 esults show that CD36 and PAFR are important mediators of HDM allergy development and that inhibiting

214 Type I IFNs are key mediators of immune defense against viruses and bacteria

215 rging evidence that specialized proresolving mediators of inflammation accelerate wound healing by pr

216 pancreatic stellate cells (PSC) as prominent mediators of inflammatory and fibrotic processes during

217 The downstream mediators of insulin-resistant pathophysiology remain un

218 es for TNF and, to a lesser extent, IL-17 as mediators of liver inflammation and fibrosis induced by

219 IL17 cytokines are central mediators of mammalian immunity.

220 s arising from cancer mutations are the main mediators of many effective cancer immunotherapies in hu

221 We identified TLR7/8 as mediators of monocyte differentiation and M2 MPhi polari

222 In the screen, we identified novel mediators of OSKM-induced senescence and validated previ

223 sdermin (GSDM) family, which are emerging as mediators of programmed cell death in a variety of proce

224 n of genes encoding neoantigens as potential mediators of resistance to immune checkpoint therapy.

225 retina, FZD4 and the ligand NDP are critical mediators of signalling and are mutated in familial exud

226 alarmins, have been recognized as signaling mediators of sterile inflammatory responses after trauma

227 n resistance, have been considered the major mediators of T2D risk; however, recent evidence shows th

228 Our study identifies TDPs as functional mediators of tardigrade desiccation tolerance, expanding

229 this syndrome requires identification of key mediators of the cytokine storm's initial wave.

230 we modeled illness and medication beliefs as mediators of the relationship between health literacy an

231 of neuroblastoma and to STAT3 and ERK1/2 as mediators of their activity.

232 by gestational age and to identify potential mediators of these associations.

233 hypoxia-inducible factors (HIFs) are central mediators of these cellular responses.

234 The primary mediators of this activity are the SMAD proteins, partic

235 ns of hypoxia, but little is known about the mediators of this effect.

236 her, our study identifies YAP/TAZ as central mediators of VEGF signaling and therefore as important r

237 udy's aim was to define the effects of these mediators on neutrophil functions and the underlying cel

238 forced LCR loop formation in the absence of mediator or cohesin occupancy.

239 rther covalent attachment of Azure A (Azu-A) mediator or glucose oxidase (GOx) enzyme.

240 id not account for or evaluate the effect of mediators other than behavioural activation.

241 the exposure-mediator, exposure-outcome, and mediator-outcome relationships in order to see how the r

242 dentified evidence networks for 70% of drug-mediator pairs where most mediators were not known direc

243 Intracellular cytotoxic mediators (perforin/granzyme B), proinflammatory cytokin

244 Additional analyses of immunoinflammatory mediator performance (T-helper Type 17 [Th17]/Th2 and Th

245 in and histamine, two important inflammatory mediators previously described in the periodontitis dise

246 Leukotriene B4 (LTB4), a proinflammatory mediator produced by the enzyme 5-lipoxygenase (5-LO), i

247 acteria-induced profibrotic and inflammatory mediator production by peritoneal leukocytes isolated fr

248 ys 3 and 7 thereafter and subjected to lipid mediator profiling.

249 RAD51 mediator proteins (i.e. paralogs) are critical for effic

250 tween proinflammatory and proresolving lipid mediators provides a link between metabolic and cellular

251 structure of Med14 facilitate a large-scale Mediator rearrangement that is essential for holoenzyme

252 Adenosine, a key extracellular signaling mediator, regulates several aspects of metabolism by act

253 ocytosis (SM) may suffer from mast cell (MC) mediator-related symptoms insufficiently controlled by c

254 We applied this approach to drug-mediator relations discovered in EDDY-CTRP analysis and

255 complemented by Skin Prick Testing (SPT) and mediator release assay to determine the IgE cross-linkin

256 DJ-1 knockdown substantially reduced mediator release, as well as Lyn kinase and spleen tyros

257 tisystem symptoms as the result of mast cell mediator release.

258 d vessels to a multidimensional one in which mediators released from multiple cells engage distinct s

259 ne B4 and prostaglandin E2 and pro-resolving mediators resolvin D1, resolvin D2, and protectin D1.

260 ega-3s) in vitro and in vivo and the omega-3 mediator, resolvin D1, in vitro increase Abeta phagocyto

261 In an effort to identify molecular mediators responsible for expansion and the tumor-promot

262 Analyses of lipid mediators revealed increased arachidonic acid and 12-lip

263 resolution cryo-electron microscopy map of a Mediator-RNA polymerase II holoenzyme reveals that chang

264 Fatty acids and lipid mediator signaling play an important role in the pathoge

265 l to neuronal-glial interactions through the mediator SNa.

266 a highly conserved specialized proresolving mediator (SPM) hosting potent anti-inflammatory and pror

267 he downstream specialized proresolving lipid mediators (SPMs) 14-hydroxydocosahexaenoic acid, 17-hydr

268 Specialized proresolving mediators (SPMs), identified in recent years, are endoge

269 e estrogen receptor (ER) coactivator protein Mediator subunit 1 (MED1) have revealed its specific rol

270 ral progenitor cells (NPCs) and recruits the Mediator subunit Med26.

271 or from an electrode during MES rely on: (i) mediators such as H2; (ii) physical contact through elec

272 Elevated activation of key inflammatory mediators such as JNK and IkappaB kinase (IKK) occurs ra

273 and lactate dehydrogenase, and inflammatory mediators such as monocyte chemoattractant protein 1 (MC

274 ponding traits, as well as examples of trans-mediators (TAGAP for LDL cholesterol).

275 tify and measure recently described chemical mediators, termed specialized pro-resolving mediators th

276 Indeed, protein levels of fibrosis signaling mediator TGF-beta remained the same and the second messe

277 as an endocrine and local anti-inflammatory mediator that antagonizes pro-inflammatory actions of FG

278 hosphate, an endogenous microglial signaling mediator that inhibits HDAC activity, enhances basal Rgs

279 mediators, termed specialized pro-resolving mediators that actively regulate the resolution of acute

280 Leukotrienes are proinflammatory lipid mediators that have been shown to be upregulated in seve

281 proresolving mediators comprise a family of mediators that include arachidonic acid-derived lipoxins

282 , identified in recent years, are endogenous mediators that include the n-3-derived families resolvin

283 s triggers production of innate inflammatory mediators that stimulate the production of matrix metall

284 ion of compliance, and analyses of treatment mediators that will facilitate further therapeutic devel

285 D73 is a newly recognized "immune checkpoint mediator" that interferes with anti-tumor immune respons

286 to the PIC is known to be facilitated by the Mediator, then acts to relieve Mediator-induced repressi

287 erfere with IFN production or its downstream mediators, thereby allowing successful infection of the

288 y which IFN-alpha serves as a proatherogenic mediator through repression of eNOS-dependent pathways.

289 ve as shuttles to protect and deliver active mediators to locally modulate cellular function during i

290 Nociceptor sensory neurons detect immune mediators to produce pain, and release neuropeptides tha

291 flammatory cytokines, followed by regulatory mediators, to ensure that this potentially destructive p

292 d with potassium ferricyanide as an electron mediator under argon or atmospheric conditions.

293 ehensive analysis of multiple cell types and mediators was performed by using flow cytometry and a mu

294 tion, exudation levels and many inflammatory mediators, was therefore evaluated in an in vivo model.

295 o systematically identify novel Golgi stress mediators, we performed a transcriptomic analysis of cel

296 Mediators were identified as genes that showed significa

297 When these mediators were incubated with diseased cells, we only fo

298 s for 70% of drug-mediator pairs where most mediators were not known direct targets for the drug.

299 suggested to involve an intracellular redox mediator, which is released during light irradiation.

300 cytokines, growth factors, and angiogenesis mediators, with CXCL12 among the most significantly upre