ライフサイエンスコーパス: medullary thymic epithelial cell

1 cells, cortical thymic epithelial cells, and medullary thymic epithelial cells.

2 a transcription factor which is expressed in medullary thymic epithelial cells.

3 xpression, particularly in keratinocytes and medullary thymic epithelial cells.

4 ssues of patients with APECED, especially in medullary thymic epithelial cells.

5 ssion of MPO mRNA predominantly localized to medullary thymic epithelial cells.

6 effort to better define the heterogeneity of medullary thymic epithelial cells.

7 or superfamily members in the development of medullary thymic epithelial cells.

8 and recruited P-TEFb to target promoters in medullary thymic epithelial cells.

9 L2 is expressed on placental endothelium and medullary thymic epithelial cells.

10 restricted to B cells, dendritic cells, and medullary thymic epithelial cells.

11 ng T cells and autoimmune regulator-positive medullary thymic epithelial cells, a key process for cen

12 reduction of autoimmune receptor-expressing medullary thymic epithelial cells (Aire1 mTEC) and a dec

13 (+) T cells preferentially damaged recipient medullary thymic epithelial cells and impaired negative

14 function of NF-kappaB2 in the development of medullary thymic epithelial cells and, thus, the control

15 n of certain organ-specific self-antigens in medullary thymic epithelial cells, and has a role in the

16 Skint-1 is expressed by medullary thymic epithelial cells, and unlike lipid-CD1

17 ng pathways that regulate the development of medullary thymic epithelial cells are not fully understo

18 First, we increase medullary thymic epithelial cells by using mice lacking

19 Both cystic and conventional medullary thymic epithelial cells express these TRAs, as

20 Medullary thymic epithelial cells expressing the Aire ge

21 on is enriched, particularly in neonates, in medullary thymic epithelial cells expressing the autoimm

22 Medullary thymic epithelial cells function as antigen-pr

23 nt in the differentiation of Aire-expressing medullary thymic epithelial cells have been defined.

24 we found no evidence that TSAs presented by medullary thymic epithelial cells in Aire+TCRmini mice a

25 also induce IA-IE expression on cortical and medullary thymic epithelial cells in an IFN-gamma-depend

26 in negative selection, including the role of medullary thymic epithelial cells in displaying tissue s

27 lls that colocalize with dendritic cells and medullary thymic epithelial cells in the thymic medulla.

28 ive sites of transcription in the nucleus of medullary thymic epithelial cells in vivo.

29 riptional regulator classically expressed in medullary thymic epithelial cells, monocytes, macrophage

30 Previous studies show that medullary thymic epithelial cell (mTEC) development invo

31 tical role in T cell tolerance by regulating medullary thymic epithelial cell (mTEC) development.

32 o-step terminal differentiation model of the medullary thymic epithelial cell (mTEC) lineage from imm

33 hough the molecular mediators that stimulate medullary thymic epithelial cell (mTEC) maturation are p

34 sting of a branching structure that contains medullary thymic epithelial cell (mTEC) networks to supp

35 h cortical thymic epithelial cell (cTEC) and medullary thymic epithelial cell (mTEC) subsets take pla

36 ism, we have previously reported that mature medullary thymic epithelial cells (mTEC(high)) expressin

37 eral self-antigens (TRA), which is in mature medullary thymic epithelial cells (mTEC(high)) partly co

38 ize the developmental pathways that generate medullary thymic epithelial cells (mTEC) from their imma

39 In the thymus, medullary thymic epithelial cells (mTEC) regulate T cell

40 in developing T cells is highly dependent on medullary thymic epithelial cells (mTEC), and mTEC devel

41 CD70 was expressed on Aire(-) and Aire(+) medullary thymic epithelial cells (mTECs) and on dendrit

42 d that Myh6 transcripts were absent in mouse medullary thymic epithelial cells (mTECs) and peripheral

43 ulate transcription of a battery of genes in medullary thymic epithelial cells (mTECs) and, consequen

44 Medullary thymic epithelial cells (mTECs) are critical i

45 In this study, we reveal a role for medullary thymic epithelial cells (mTECs) during iNKT ce

46 ce of autoimmune regulator (Aire)-expressing medullary thymic epithelial cells (mTECs) during the emb

47 Medullary thymic epithelial cells (mTECs) eliminate self

48 Medullary thymic epithelial cells (mTECs) express a broa

49 expression of peripherally restricted Ags by medullary thymic epithelial cells (mTECs) is associated

50 of tissue-restricted self antigens (TRAs) in medullary thymic epithelial cells (mTECs) is essential f

51 us tissue-restricted self-antigens (TRAs) in medullary thymic epithelial cells (mTECs) is essential t

52 ession of tissue-specific antigens (TSAs) by medullary thymic epithelial cells (Mtecs) leads to delet

53 roles for bone marrow (BM)-derived APCs and medullary thymic epithelial cells (mTECs) on the convent

54 Aire-expressing medullary thymic epithelial cells (mTECs) play a key rol

55 Medullary thymic epithelial cells (mTECs) play an essent

56 Medullary thymic epithelial cells (mTECs) play an import

57 We show that bone marrow (BM) APCs and medullary thymic epithelial cells (mTECs) played nonover

58 plethora of tissue-restricted Ags (TRAs) by medullary thymic epithelial cells (mTECs) plays an essen

59 ular, autoimmune regulator (Aire)-expressing medullary thymic epithelial cells (mTECs) provide a spec

60 Aire functions in terminally differentiated medullary thymic epithelial cells (MTECs) to derepress t

61 In medullary thymic epithelial cells (mTECs), the Autoimmun

62 Central tolerance mechanisms involve medullary thymic epithelial cells (mTECs), which use end

63 f-tolerance in developing T cells depends on medullary thymic epithelial cells (mTECs), whose develop

64 ns2 gene specifically in the Aire-expressing medullary thymic epithelial cells (mTECs), without affec

65 neages--cortical thymic epithelial cells and medullary thymic epithelial cells (mTECs)--are yet to be

66 g-presenting, autoimmune regulator (AIRE)(+) medullary thymic epithelial cells (mTECs).

67 a2(+) stage in the absence of RelB-dependent medullary thymic epithelial cells (mTECs).

68 derived TEPs differentiate into cortical and medullary thymic epithelial cells, reconstitute the norm

69 nity by promoting self-antigen expression in medullary thymic epithelial cells, such that developing

70 Autoimmunity is largely prevented by medullary thymic epithelial cells (TECs) through their e

71 y a marked reduction in the number of mature medullary thymic epithelial cells that express CD80 and

72 iated down-regulation of ICA69 expression in medullary thymic epithelial cells, thus providing a nove

73 r of surface MHC-self peptide complexes from medullary thymic epithelial cells to thymic DC.

74 2, Bcl-3 functions within stroma to generate medullary thymic epithelial cells, which are essential f

75 Unlike medullary thymic epithelial cells, which express and pre

76 ngly autoimmune regulator-expressing, mature medullary thymic epithelial cells, which play a pivotal

77 expression of many tissue-specific genes in medullary thymic epithelial cells, which plays an import