ライフサイエンスコーパス: meioses

1 nerational instability ( approximately 2% of meioses).

2 omosome behavior in female and hermaphrodite meioses.

3 o precise chromosomal positions and specific meioses.

4 mbinants were obtained from female than male meioses.

5 s using a set of 47 families comprising 3546 meioses.

6 haracterization of 3026 male and 3002 female meioses.

7 ely sterile and defective in male and female meioses.

8 oy but a single crossover in the majority of meioses.

9 al interspecific backcrosses, comprising 188 meioses.

10 etween meioses exhibiting trisomy and normal meioses.

11 bspecific intercross panel representing 1170 meioses.

12 cted families with a total of 14 informative meioses.

13 lassification of the recombination status of meioses.

14 es between meioses exhibiting UPD and normal meioses.

15 tional patterns by direct observation of 731 meioses.

16 collected from a relatively small number of meioses.

17 oximately 1.4-fold greater than that of male meioses.

18 t 4.5 cM shows no recombination in over 1400 meioses.

19 covering all three products of single female meioses.

20 xcess of recombination in female versus male meioses, (2) an overall decline in female:male recombina

21 terchromosomal exchanges in 2/15 informative meioses, a rate consistent with the genetic distance.

22 >4 million informative SNPs from 23 complete meioses allowed us to map 2,032 maternal and 1,342 pater

23 Analysis of affected meioses alone revealed no recombination with an addition

24 nation locations are highly variable between meioses, although total crossover numbers are tightly re

25 pedigrees, with >770 potentially informative meioses altogether, were genotyped with a subset of 2,98

26 ped to mouse chromosome 11 on a total of 246 meioses and confined to a 4.60-million basepair critical

27 els are equivalent in hotspot and nonhotspot meioses and do not change in mts mutants, indicating tha

28 We identified crossovers in these meioses and fitted the Housworth-Stahl "interference-esc

29 ected recombination events from over 100,000 meioses and have constructed sex-specific genetic maps a

30 apping is limited by the number of available meioses and informative marker density.

31 Gene IBD is traced through ancestral meioses and is defined relative to founders of a pedigre

32 ify all exchanges in 186 female and 160 male meioses and to show (1) significant excess of recombinat

33 s revealed that deletions occurred in 44% of meioses and usually affected both chromatids of the muta

34 chiasma interference in male than in female meioses, and (4) lack of correlation between exchange fr

35 the two independent populations of parental meioses, and genetic maps were constructed to represent

36 implicitly assuming that, in some sense, all meioses connecting two affected individuals are informat

37 ssover and noncrossover events of individual meioses directly at active hotspots while retaining the

38 F." Additional genotyping of as many as 2407 meioses established a high resolution genetic map with g

39 on the basis of 40 markers and the number of meioses estimated to have taken place during the crossin

40 sp I site that cosegregates with fa in 1,028 meioses examined in obese F2 progeny from two crosses (B

41 ted for differences in recombination between meioses exhibiting trisomy and normal meioses.

42 to inspect recombination differences between meioses exhibiting UPD and normal meioses.

43 al resources afforded 450 mostly phase-known meioses for map assembly.

44 recombination sites in a collection of 1154 meioses from 1155 progeny generated in the six crosses.

45 Analysis of 1139 female meioses from an intersubspecific backcross using 15 PCR-

46 phism (SNP)-chip data, comprising over 6,000 meioses from nine cohorts.

47 ed by segregation analysis of more than 1650 meioses from three interspecific backcrosses.

48 Of the 42 meioses genotyped in this pedigree, 39 subjects (16 affe

49 hree affected individuals separated by eight meioses identified a single shared novel heterozygous va

50 Analysis of unaffected meioses identified only one healthy 86-year-old male who

51 es, including 147,327 male and 71,687 female meioses in Holstein, and 108,163 male and 37,008 female

52 Holstein, and 108,163 male and 37,008 female meioses in Jersey, respectively.

53 aplotype analyses of affected and unaffected meioses in six families provided maximum linkage informa

54 ts chromosome pairs to one crossover in most meioses in the nematode Caenorhabditis elegans; this sys

55 In meioses in which two of the three model chromosomes expe

56 5, where there are 109 recombinants/Mb (4882 meioses), in contrast to flanking regions of 14.6 recomb

57 satellite markers and 5 known genes on a 968-meioses intersubspecific backcross segregating for dfw [

58 pendent crossing over in yeast and mammalian meioses involves the mismatch repair protein homologs MS

59 tabilities in transmission of FRAXE among 43 meioses involving intermediate or premutation sized alle

60 he number of crossovers observed in parental meioses leading to the transmission of alleles to their

61 ution of the recombination events underlying meioses leading to UPD.

62 monozygotic twins was detected among the 304 meioses mapped to highest resolution.

63 ot limited to maintaining arrest in abnormal meioses; mec1-1, rad24, and rad17 single mutants have ad

64 nsuming to characterize the large numbers of meioses needed to generate statistically robust data set

65 In our sample of 37 meioses, nine informative markers did not recombine with

66 Considerations such as the number of meioses observed, the heterozygosity and physical distan

67 When only the affected meioses of this kindred were analyzed, LOD scores remain

68 erated a high-resolution genetic map (> 1800 meioses) of the Clock locus.

69 For a typical setup with 50 informative meioses on 50 markers uniformly distributed on a chromos

70 families, with an average of 171 informative meioses per locus.

71 ite loci, with an average of 608 informative meioses per locus.

72 phic STRs by tracing each locus over 222,000 meioses, resulting in the largest collection of Y-STR mu

73 The data also reveal that one or two meioses separate different isolates, showing that P. fal

74 Using the number of meioses separating each pair of autozygous alleles and t

75 etween relationships with the same number of meioses separating the individuals under consideration (

76 r of common ancestors and the same number of meioses separating the individuals under consideration.

77 me were also evaluated, with male and female meioses showing significantly different patterns of reco

78 e-wide levels of recombination in individual meioses; studies analyzing temporal aspects of the mamma

79 y early conjugation among products of single meioses, such that the duration of the free-living haplo

80 imately 22,000 SNPs informing on a subset of meioses supported map integrity.

81 ution of the recombination events underlying meioses that lead to trisomy.

82 l of DNA, consisting of 520 F2 progeny (1040 meioses) that has been anchored to a zebrafish genetic l

83 On 249 meioses, the locus was confined to a 2.7-Mb region, whic

84 ere we test a single family with 11 relevant meioses transmitting autosomal dominant acute myelogenou

85 y of nondisjunction among 1784 embryos (3568 meioses) was 15.9%.

86 Using SNP array data from 98 meioses, we identified 103 sites affected by NCO, of whi