ライフサイエンスコーパス: meiosis

1 mbination by altering chromatin structure in meiosis.

2 also localizes along chromosome arms during meiosis.

3 its translational capacity to the process of meiosis.

4 between paired homologous chromosomes during meiosis.

5 n numerous tissues, particularly during male meiosis.

6 os without fertilization through a truncated meiosis.

7 and repair of stalled replication forks and meiosis.

8 am that is conducive for progression through meiosis.

9 ene (also known as PRD2), thereby disrupting meiosis.

10 tion of sister chromatids during mitosis and meiosis.

11 aterial to daughter cells during mitosis and meiosis.

12 a loss of haploid spermatids due to impeded meiosis.

13 ls and why non-germline cells do not undergo meiosis.

14 DSB formation to form crossovers crucial for meiosis.

15 ule growth as the acentriolar oocyte resumes meiosis.

16 ensure proper chromosome segregation during meiosis.

17 ring premeiotic G2 arrest of Drosophila male meiosis.

18 quisite for their correct segregation during meiosis.

19 homologous intra-molecular recombination in meiosis.

20 al acetylation and its essential role during meiosis.

21 enomic stability in somatic cells and during meiosis.

22 teristics in common with conventional extant meiosis.

23 ites of double-strand break formation during meiosis.

24 lates premeiotic G2 phase of Drosophila male meiosis.

25 he fidelity of chromosome segregation during meiosis.

26 egregation of chromosomes during mitosis and meiosis.

27 t on chromosome segregation during wild type meiosis.

28 ocyte's centre to the plasma membrane during meiosis.

29 of highly stringent checkpoints during male meiosis.

30 6c-Aurora A axis in the resumption of female meiosis.

31 rm cell apoptosis and a greater incidence of meiosis.

32 to differentiate into spermatocytes to enter meiosis.

33 e structures and processes involved in their meiosis.

34 ne/threonine kinases involved in mitosis and meiosis.

35 rk stability contributes to DNA integrity in meiosis.

36 d the mechanism of chromosome segregation in meiosis.

37 ce to advance our molecular understanding of meiosis.

38 te the exit from pluripotency and entry into meiosis.

39 for its role in chromosome compaction during meiosis.

40 ed and exhibits lower spore viability during meiosis.

41 ow the three isoforms function to coordinate meiosis.

42 at are readily broadcast through mitosis and meiosis.

43 al for chromosome segregation in mitosis and meiosis [1].

44 ta, maintains bivalent cohesion in mammalian meiosis [2-6].

45 g homologues named Ime4 and KAR4 (Inducer of meiosis 4 and Karyogamy protein 4), and Female-lethal (2

46 s much higher in male meiosis than in female meiosis (490 cM vs. 290 cM), female recombination is hig

47 investigated the effects of ATZ exposure on meiosis, a key step in gametogenesis in mammals.

48 During Caenorhabditis elegans oocyte meiosis, a multi-protein ring complex (RC) localized bet

49 o10 is not absolutely essential for mitosis, meiosis, adult survival, or fertility.

50 Three key steps in meiosis allow diploid organisms to produce haploid gamet

51 yonic exposure to ATZ disrupts prophase I of meiosis and affects normal follicle formation in female

52 rocesses that include mitotic proliferation, meiosis and cellular remodeling.

53 r the p53 family in ensuring the fidelity of meiosis and establishes CEP-1 as a critical determinant

54 id cells of Saccharomyces cerevisiae undergo meiosis and form haploid spores, a process collectively

55 n ideal model for studying the plasticity of meiosis and how it can be modulated.

56 functions beyond Gle1 mitotic targeting and meiosis and impacts nuclear and nucleolar architecture w

57 s enter meiosis, whereas in males they delay meiosis and instead lose pluripotency, activate an irrev

58 The role of cyclin A2 in female meiosis and its dynamics during the transition from meio

59 tact) at prophase I are stimulated to resume meiosis and mature to metaphase II, a sequence of events

60 hat received the stress during the stages of meiosis and microspore formation but had no effect on mo

61 chromatin organization transmissible through meiosis and mitosis.

62 ropose that a meiotic-vegetal center couples meiosis and oocyte patterning.

63 ays are disturbed in gem3/aug6-1 during male meiosis and pollen mitosis I using fluorescent MT-marker

64 ion in the stamen envelope, occurring during meiosis and pollen mitosis I, we identified a novel, thi

65 ed shredding of the X-chromosome during male meiosis and produced extreme male bias among progeny in

66 Coexisting in a DNA system, meiosis and recombination are two indispensible aspects

67 nism by which overexpression of Cx43 reboots meiosis and rescues BTB function was also examined.

68 Connexin 43 reboots meiosis and reseals blood-testis barrier following toxic

69 in the testis with aspermatogenesis reboots meiosis and reseals toxicant-induced BTB disruption, eve

70 directs localized H3K36 demethylation during meiosis and spermatogenesis.

71 es indicated that Huwe1 is not essential for meiosis and spermiogenesis, but can result in accumulati

72 e of yeast m(6)A methyltransferase, Ime4, in meiosis and sporulation in diploid strains is very well

73 ow that mTORC1 function is critical for male meiosis and the inactivation of sex chromosomes.

74 al cells, with an initial peak around pollen meiosis and then later during pollen wall development.

75 ion and persistence of DNA damage markers in meiosis and to problems with cohesion stability at the c

76 of proteins supports mitotic proliferation, meiosis, and DNA repair to control genomic stability.

77 defects in embryonic polarity establishment, meiosis, and the integrity of the eggshell permeability

78 ch recombination sites are determined during meiosis are becoming clearer following a phylogenomic an

79 , and approximately 1% were able to complete meiosis as demonstrated by their haploid status and the

80 lin vivoassay in tubules displaying signs of meiosis as noted by the presence of round spermatids.

81 that N-terminal acetylation is critical for meiosis, as it regulates the assembly of the synaptonema

82 in TEX15, encoding a DDR factor important in meiosis, associated with hereditary breast cancer (p = 0

83 s during anther development, involving early meiosis-associated events and late pollen wall formation

84 many nematodes [1] facilitates the study of meiosis because variation is easily recognized [2-4].

85 YTHDC2-deficient male germ cells enter meiosis but have a mixed identity, maintaining expressio

86 on of genes downstream from glp-1 to promote meiosis but not by activation of the IIS or TORC1 pathwa

87 any studies have hinted at a role for p53 in meiosis, but how it functions in this process is poorly

88 TrCP-deficient male germ cells did not enter meiosis, but instead underwent apoptosis.

89 dentify the genes and pathways important for meiosis, but the parts list is still poorly defined.

90 and other repetitive sequences can drive in meiosis by cheating the segregation process [2], but the

91 locations of recombination hot spots during meiosis by sequence-specific DNA binding and trimethylat

92 enetically active centromeres (functional in meiosis) by half-tetrad analysis.

93 afish to a nuclear asymmetry at the onset of meiosis called the chromosomal bouquet.

94 During meiosis, centromeres in some species undergo a series of

95 non termed the "maternal age effect." During meiosis, cohesion between sister chromatids keeps recomb

96 pindles and, after fertilization with sperm, meiosis completion and formation of normal diploid zygot

97 Differentiation programs such as meiosis depend on extensive gene regulation to mediate c

98 osis less recombinogenic than male wild-type meiosis do not apply in the mutant context.

99 steps, where mitotic proliferation precedes meiosis during spermatogenesis, are observed in a wide v

100 crossover formation in human male and female meiosis, enabled by modeling analysis.

101 hment of the polyspermy block, completion of meiosis, entry into mitosis, selective recruitment and d

102 o not undergo self-renewal but rapidly enter meiosis following transplantation.

103 r each chromosome, in all of the products of meiosis for each oocyte.

104 e that haspin kinase regulates resumption of meiosis from prophase arrest, chromosome condensation, a

105 tween pairs of homologous chromosomes during meiosis from yeast to humans, plays important roles in p

106 aceous structure ubiquitously present during meiosis from yeast to humans.

107 , in which activation of germline (including meiosis) functions drive oncogenesis, and we extend this

108 ctions of Xrs2, including DNA end resection, meiosis, hairpin resolution, and cellular resistance to

109 During female meiosis, haploid eggs are generated from diploid oocytes

110 This gene reshuffling during meiosis has a significant influence on evolution and als

111 zoans, delineation of the role of PP2A B' in meiosis has been hindered by its myriad of other essenti

112 ly in germ cell development or just prior to meiosis has remained unclear.

113 In budding yeast meiosis, homologous chromosomes become linked by chiasma

114 During meiosis, homologous chromosomes undergo crossover recomb

115 forming parallel guanine quadruplexes during meiosis; however, the underlying mechanism is not well d

116 cytokinesis are not caused by alterations in meiosis I (MI or meiosis II (MII) chromosome dynamics, b

117 on (G2/M transition) and progression through meiosis I (MI) are two key stages for producing fertiliz

118 e promoting complex/cyclosome (APC/C) during meiosis I (MI) exit.

119 and its dynamics during the transition from meiosis I (MI) to meiosis II (MII) remain unclear.

120 on errors are common during female mammalian meiosis I (MI).

121 immature oocytes are arrested at prophase of meiosis I (MI).

122 mia and result from an inability to complete meiosis I (MI).

123 these proteins on centromere orientation in meiosis I .

124 ombination, and chromosome missegregation in meiosis I and meiosis II.

125 depolymerization of spindle microtubules in meiosis I and meiosis II.

126 pendent chromosome segregation during oocyte meiosis I and nuclear assembly during the transition fro

127 ster chromatids together, first from arms in meiosis I and then from the centromere region in meiosis

128 the centromere is required for protection.In meiosis I centromeric cohesin is protected by Sgo2 from

129 Completion of meiosis I could be restored by ROS scavengers, showing t

130 The proper distribution of crossovers during meiosis I ensures accurate chromosome segregation at the

131 ich recombinant homologs missegregate during meiosis I is significantly greater in SOD knockdown oocy

132 and Bub1 kinase activities localise Sgo2 in meiosis I preferentially to the centromere and pericentr

133 4 kinases contribute to initiate acentriolar meiosis I spindle formation.

134 ocytes respond to DNA damage by arresting in meiosis I through activity of the Spindle Assembly Check

135 dc55) activity undergo a premature exit from meiosis I which results in a failure to form bipolar spi

136 on of segregation-competent bivalents during meiosis I, and findings suggest that age-dependent deple

137 omatids of the X chromosomes separate during meiosis I, and homologous X chromatids segregate to the

138 subunit localizes first along chromosomes in meiosis I, becoming restricted to the centromere region

139 sley et al. (2016) use the unique biology of meiosis I, in which the cell can exit the division witho

140 nsistent with the absence of key features of meiosis I, including synapsis and recombination.

141 During oocyte meiosis I, MEL-28-PP1c disassembles kinetochores in a ti

142 ing high-resolution imaging, we find that in meiosis I, microtubules initially form a "cage-like" str

143 Mouse oocytes carrying DNA damage arrest in meiosis I, thereby preventing creation of embryos with d

144 unique reductional chromosome segregation of meiosis I, which also results in chromosomal exchanges.

145 Here, we propose that meiosis I-specific modulators of reductional segregation

146 osomes failed to segregate accurately during meiosis I.

147 f the SAC to inhibit bivalent segregation in meiosis I.

148 sover (CO) formation between homologs during meiosis I.

149 etochore cross-linking and co-orientation in meiosis I.

150 e critical for proper homolog segregation in Meiosis I.

151 an lead to missegregation of homologs during meiosis I.

152 ary for proper chromosome disjunction during meiosis I.

153 not play a role in centromere protection in meiosis I.

154 ot caused by alterations in meiosis I (MI or meiosis II (MII) chromosome dynamics, but instead result

155 Sister chromatid attachment during meiosis II (MII) is maintained by securin-mediated inhib

156 during the transition from meiosis I (MI) to meiosis II (MII) remain unclear.

157 structures that engulf haploid cells during meiosis II (MII).

158 ty acids at a time that correlates well with meiosis II progression, concomitant with phospholipid re

159 ane (PSM) that is synthesized de novo during meiosis II to sequester the dividing nuclei in sporulati

160 ivision) and sgo1 (shugoshin) mutants during meiosis II when the sister chromatids exhibit random dis

161 t the segregation of the Y chromatids during meiosis II, causing female-biased sex ratio in progeny.

162 se to DNA damage in fully mature eggs during meiosis II, despite the divisions being separated by jus

163 by NDT80 but not translated until the end of meiosis II.

164 hromatids together until their separation in meiosis II.

165 d chromosome missegregation in meiosis I and meiosis II.

166 are kept together until their separation in meiosis II.

167 ion of spindle microtubules in meiosis I and meiosis II.

168 sis I and then from the centromere region in meiosis II.

169 dial microtubule arrays (RMAs) at the end of meiosis II.

170 osit an apomictic allele that arrests female meiosis in diploids, so that the plant produces diploid

171 n expectations, not for initiating the first meiosis in female germ cells at the SD stage.

172 r-complete parts list of genes important for meiosis in fission yeast, providing a valuable resource

173 rCP regulates the transition from mitosis to meiosis in male germ cells by targeting DMRT1 for degrad

174 Meiosis in mammalian females entails two reductive divis

175 Fertilization occurs during female meiosis in most animals, which raises the question of wh

176 2 facilitates a clean switch from mitosis to meiosis in mouse germ cells, revealing a conserved role

177 he fidelity of chromosome segregation during meiosis in mouse oocytes.

178 d highlight the need for detailed studies of meiosis in nonmodel species.

179 oss eukarya - either just prior to or during meiosis in single-celled eukaryotes, and in stem cells a

180 plex with Cdh1 has an unexpected function in meiosis in that it is essential for meiotic resumption.

181 GCs are initially formed but are lost during meiosis in the developing ovary, leading to adult female

182 comprehensive catalog of genes important for meiosis in the fission yeast, Schizosaccharomyces pombe

183 nsiently attenuated in germ cells undergoing meiosis in vivo and its forced reduction induces meiosis

184 f the alga, under which the zygote undergoes meiosis, in a positive manner, similar to the regulation

185 17,669 novel isoforms at different stages of meiosis, including antisense and read-through transcript

186 atic reprogramming of gene expression during meiosis, including regulated splicing of a number of cru

187 ults show that RA plays an important role in meiosis induction and gametogenesis in adult medaka but

188 identified a parasite ortholog of the Mei2 (Meiosis inhibited 2) RBP that is conserved among Plasmod

189 hromosomes are segregated during mitosis and meiosis is a major puzzle of biology and biophysics.

190 Meiosis is a specialized cell division that generates ga

191 Meiosis is a specialized cell division, essential in mos

192 Meiosis is a unique process that allows the generation o

193 nd synapsis of homologous chromosomes during meiosis is crucial for producing genetically normal game

194 Proper segregation of chromosomes in meiosis is essential to prevent miscarriages and birth d

195 Although meiosis is evolutionarily conserved, many of the underly

196 1026 1027 References 1027 Meiosis is fundamental to sexual reproduction and create

197 Meiosis is fundamental to sexual reproduction and create

198 Resumption of meiosis is heralded by germinal vesicle breakdown, conde

199 r, the number and distribution of COs during meiosis is highly constrained.

200 A key step of meiosis is homologous recombination, which promotes homo

201 It remains largely unknown how meiosis is initiated in germ cells and why non-germline

202 we provide evidence that oocyte reentry into meiosis is instead associated with a shift in the patter

203 hat proper progression of germ cells through meiosis is licensed by YTHDC2 through post-transcription

204 ies with combined loss of Sohlh1 and Sohlh2, meiosis is not affected and proceeds normally.

205 Meiosis is the cellular program by which a diploid cell

206 Meiosis is the cellular program that underlies gamete fo

207 The switch from mitosis to meiosis is the key event marking onset of differentiatio

208 Fundamental to meiosis is the process of homologous recombination, wher

209 A key feature of meiosis is the step-wise removal of cohesin, the protein

210 tiation is tightly coupled with the onset of meiosis, it is of significant interest to determine how

211 e sex differences in embryos is the onset of meiosis, known to be regulated by retinoic acid (RA) in

212 that the factors that make wild-type female meiosis less recombinogenic than male wild-type meiosis

213 sis in vivo and its forced reduction induces meiosis-like cytological changes in cultured germline st

214 During meiosis, LINC connects the centrosome with telomeres rat

215 lve concatenation between chromosomes during meiosis, localization of topoisomerase IIalpha to bivale

216 all eukaryotes and suggests that primordial meiosis may have had many characteristics in common with

217 ritional starvation, the master regulator of meiosis Mei2 inactivates Mmi1, thereby allowing expressi

218 During mitosis and meiosis, microtubule (MT) assembly is locally upregulate

219 Along with errors in meiosis, mitotic errors during post-zygotic cell divisio

220 Nevertheless, conventional forms of meiosis occur in all major groups of eukaryotes, includi

221 In flowering plants, male gametes arise via meiosis of diploid pollen mother cells followed by two r

222 ter to characterize the transcriptome in the meiosis of fission yeast.

223 s an essential process that occurs in female meiosis of metazoa to reset centriole number in the zygo

224 Mitosis and meiosis of the germline nucleus and amitotic division of

225 In addition to the effect of meiosis on genetic variation, sequence polymorphisms bet

226 This finding confirms that meiosis originated in the common ancestor of all eukaryo

227 Once germ cells enter meiosis, pachytene spermatocytes produce RA to coordinat

228 During meiosis paired homologous chromosomes undergo recombinat

229 During meiosis, paired homologous chromosomes (homologs) become

230 Many of these changes are erased as meiosis proceeds, however, illustrating homeostatic beha

231 Meiosis produces haploid gametes through a succession of

232 on usage required to fine-tune the timing of meiosis progression.

233 Female meiosis provides an opportunity for selfish genetic elem

234 anting pronuclei shortly after completion of meiosis rather than shortly before the first mitotic div

235 overall entails a modulation of cell cycle, meiosis-related and nutrient transporter genes, suggesti

236 We show that the meiosis-related EECTG (MEIOB) and its nearby CT-ncRNA ha

237 Faithful chromosome segregation in meiosis requires crossover (CO) recombination, which is

238 The passage of genetic information during meiosis requires exceptionally high fidelity to prevent

239 Meiosis requires transient removal of the outer kinetoch

240 Errors in meiosis result in miscarriages and are the leading cause

241 t germinal vesicle stage were prevented from meiosis resumption and cultured in a medium with or with

242 In female meiosis, selfish elements drive by preferentially attach

243 meiotic chromosomes, even though mitosis and meiosis share many processes, including the DNA replicat

244 ly to arise in cases of PTH (Oenothera-like) meiosis since haplotypes are transferred as entire block

245 is4 locus, is found in diploids that undergo meiosis soon after their formation, but not in diploids

246 Our studies provide insight into how meiosis-specific cohesin complexes are regulated to ensu

247 provide evidence that there are at least two meiosis-specific cohesin complexes.

248 Multiple meiosis-specific cohesion proteins act to facilitate hom

249 The conserved meiosis-specific Dmc1 recombinase catalyzes homologous r

250 show that a G/C-rich motif associated with a meiosis-specific DNA double-strand break (DSB) in Saccha

251 The meiosis-specific DNA strand exchange protein, DMC1, prom

252 ween G/C-rich DNA segments associated with a meiosis-specific DSB site.

253 dea that the G/C-rich motifs associated with meiosis-specific DSBs fold into intramolecular G-quadrup

254 We find that meiosis-specific HORMA domain proteins span a gap betwee

255 Cohesin complexes containing meiosis-specific kleisin subunits govern most aspects of

256 Smk1 is a meiosis-specific MAP kinase (MAPK) in budding yeast that

257 Smk1 is a meiosis-specific mitogen-activated protein kinase (MAPK)

258 ost Spo11-initiated crossovers, required the meiosis-specific MutLgamma resolvase.

259 an intramolecular reaction that requires the meiosis-specific protein Ssp2.

260 ytic activity for substrates require Ssp2, a meiosis-specific protein that is translationally repress

261 Moreover, we report a novel meiosis-specific protein, Sa15, as an interacting partne

262 ntrast, the second complex, which depends on meiosis-specific proteins SOLO, SUNN, and ORD is require

263 ich include cohesin complexes and additional meiosis-specific proteins.

264 ng regulated splicing of a number of crucial meiosis-specific RNAs.

265 , the sole stable complex that contains both meiosis-specific septins is a linear Spr28-Spr3-Cdc3-Cdc

266 Ama1 is a meiosis-specific targeting subunit of the anaphase-promo

267 In fission yeast, meiosis-specific transcripts are selectively eliminated

268 emonstrate here that exposure to ATZ affects meiosis, spermiogenesis and reduces the spermatozoa numb

269 is addressed in budding yeast, where during meiosis Spr3 and Spr28 replace the mitotic septin subuni

270 ific type of biased segregation in mammalian meiosis suggest that it arises from centromeric satellit

271 mation of deep membrane invaginations during meiosis, suggesting an effect on cortical myosin.

272 inkage to their respective centromere during meiosis, suggesting the presence of recombinational supp

273 ed with another Cre that is expressed during meiosis: Sycp-1-Cre This second example of LoxP inhibiti

274 Early in meiosis, Tel1 absence causes widespread changes in DSB d

275 ld type recombination is much higher in male meiosis than in female meiosis (490 cM vs. 290 cM), fema

276 rmination, during which the zygote undergoes meiosis that gives rise to four vegetative cells.

277 failure to increase ploidy prior to entering meiosis, the fecundity of parthenogenetic A. neomexicana

278 During meiosis, the formation of crossovers (COs) generates gen

279 Meiosis, the mechanism of creating haploid gametes, is a

280 is known about the three isoforms in female meiosis, the similarities and differences between kinase

281 exit from prophase I is a landmark event of meiosis, the underlying mechanism regulating SC destruct

282 ation for the three products of human female meiosis: the first and second polar bodies (PB1 and PB2)

283 When cells enter meiosis, their chromosomes reorganize as linear arrays o

284 es that fail to prepare the Y chromosome for meiosis, thus providing evidence that the rapid evolutio

285 ers exploit the asymmetry inherent in female meiosis to bias their transmission.

286 permatogenesis at least through the steps of meiosis to generate round spermatids in testes of rats t

287 gans RMI1 homolog-1 (RMH-1) functions during meiosis to promote both CO and NCO HR at appropriate chr

288 degradation and thereby controls the mitosis-meiosis transition in mouse male germ cells.

289 The mitosis-meiosis transition is essential for spermatogenesis.

290 Investigation in meiosis using pollen mother cells also revealed that it

291 oteins Stromalin (SA) and Nipped-B (SCC2) in meiosis, we provide evidence that there are at least two

292 onuclease (VDE) to initiate recombination in meiosis, we show that chromosome structure influences th

293 ic elements compete for transmission through meiosis, when haploid gametes are created from a diploid

294 The bouquet is a universal feature of meiosis where all telomeres cluster to one pole on the n

295 In females, fetal germ cells enter meiosis, whereas in males they delay meiosis and instead

296 tment was initiated before oocyte entry into meiosis, which occurs during the embryonic period in fem

297 e has revealed an essential role for Cdk2 in meiosis, which renders Cdk2 knockout (KO) mice sterile.

298 he spectrum of derived and uncommon forms of meiosis will improve our understanding of many still mys

299 result, the myt1 mutant spermatocytes enter meiosis with multipolar spindles.

300 e in fission and budding yeast, and studying meiosis with poisoned microtubules indicates that the in