ライフサイエンスコーパス: melanin-concentrating hormone

1 antially more abundant than those containing melanin-concentrating hormone.

2 cells were distinct from those that express melanin-concentrating hormone.

3 wly generated neurons expressing ENK, OX, or melanin-concentrating hormone.

4 escribed neuropeptides hypocretin/orexin and melanin-concentrating hormone.

5 binoid-1, melanin-concentrating hormone, and melanin-concentrating hormone-1 receptor expression.

6 related peptide, melanocortins, orexins, and melanin concentrating hormone, among other mediators.

7 e mice, C75 markedly increased expression of melanin-concentrating hormone and its receptor in the hy

8 particular interest: pattern A, hypothalamic melanin-concentrating hormone and proopiomelanocortin bu

9 o be present, eliminated some neurons (Hcrt, melanin-concentrating hormone, and adenosine deaminase-c

10 in the brain, including neurons that secrete melanin-concentrating hormone, and culminates in the rel

11 er of hypothalamic neurons producing orexin, melanin-concentrating hormone, and histamine in 7 narcol

12 These cells included those producing orexin, melanin-concentrating hormone, and luteinizing hormone-r

13 vitro, but not in inhibiting cannabinoid-1, melanin-concentrating hormone, and melanin-concentrating

14 nsmitters found in the LHA including orexin, melanin-concentrating hormone, and nesfatin-1.

15 opiomelanocortin, thyroid-releasing hormone, melanin-concentrating hormone, and orexin expression.

16 proopiomelanocortin in the arcuate nucleus, melanin-concentrating hormone, and orexin in the lateral

17 duces excitatory synaptic strength onto both melanin-concentrating hormone- and orexin-expressing neu

18 Y (NPY), agouti-related protein (AgRP), and melanin-concentrating hormone] and anorexigenic [pro-opi

19 orexigenic peptides, enkephalin, orexin and melanin-concentrating hormone, as revealed using real-ti

20 nic neuropeptides Agouti-related peptide and melanin-concentrating hormone but surprisingly has no ef

21 citatory synaptic inputs to both orexin- and melanin-concentrating hormone expressing LHA neurons pro

22 In addition, both orexin and melanin-concentrating hormone fibers made numerous close

23 Human melanin-concentrating hormone (hMCH) and many of its ana

24 Human melanin-concentrating hormone (hMCH) is a nonselective n

25 Human melanin-concentrating hormone (hMCH) is a potent but non

26 n the paraventricular nucleus and orexin and melanin-concentrating hormone in the perifornical latera

27 mygdala, OX, and another orexigenic peptide, melanin-concentrating hormone, in the perifornical later

28 xpression, increased hypothalamic Orexin and melanin-concentrating hormone, increased food intake, re

29 A, and genetic disruption of kappaOR reduced melanin concentrating hormone-induced liver steatosis.

30 In contrast, melanin-concentrating hormone levels are minimal during

31 Melanin-concentrating hormone levels increase at sleep o

32 Sections were immunostained for Hcrt-1, melanin concentrating hormone (MCH) and alpha synuclein

33 pus, lateral hypothalamic neurons containing melanin concentrating hormone (MCH) and GABA send long a

34 Melanin concentrating hormone (MCH) and the orexins (A a

35 e a selective association of these INRs with melanin concentrating hormone (MCH) and tyrosine hydroxy

36 The importance of melanin concentrating hormone (MCH) in the control of en

37 Melanin concentrating hormone (MCH) is a cyclic neuropep

38 Melanin concentrating hormone (MCH) is a hypothalamic ne

39 Melanin concentrating hormone (MCH) is an orexigenic hyp

40 Melanin concentrating hormone (MCH) is involved in regul

41 Melanin concentrating hormone (MCH) is recognised as a h

42 The neuropeptide melanin concentrating hormone (MCH) is synthesised only

43 for body weight, mice with selective loss of melanin concentrating hormone (MCH) neurons were generat

44 ropeptide systems NPY, AGRP, orexin (OX) and melanin concentrating hormone (MCH), 3) special inductio

45 The current studies focused on melanin concentrating hormone (MCH), another orexigenic

46 s in the LH, expressing hypocretin/orexin or melanin concentrating hormone (MCH), have been shown to

47 in hypothalamus of neuropeptide Y (NPY) and melanin concentrating hormone (MCH), two neuropeptides t

48 4% of these neurons express the neuropeptide melanin concentrating hormone (MCH).

49 that produce either orexins (hypocretins) or melanin concentrating hormone (MCH).

50 the number of hypocretin (29.7% reduction), melanin concentrating hormone (MCH; 24.7% reduction), an

51 in the LHA and in the posterior Pe coexpress melanin-concentrating hormone (MCH) and glutamic acid de

52 wn classes of LHA projection neurons, namely melanin-concentrating hormone (MCH) and hypocretin/orexi

53 Melanin-concentrating hormone (MCH) and hypocretin/orexi

54 Among these, melanin-concentrating hormone (MCH) and neuropeptide Y (

55 Orexigenic hormones, melanin-concentrating hormone (MCH) and orexin, were sig

56 The melanin-concentrating hormone (MCH) and orexin/hypocreti

57 ropeptide Y (NPY) in the arcuate nucleus and melanin-concentrating hormone (MCH) and orexins/hypocret

58 Two neuropeptides, melanin-concentrating hormone (MCH) and the orexins (ORX

59 orexigenic peptides hypocretin (orexin) and melanin-concentrating hormone (MCH) are involved in the

60 Transgenic mice overexpressing melanin-concentrating hormone (MCH) are obese and a seco

61 Hypothalamic neurons that utilize melanin-concentrating hormone (MCH) as a neuromodulator

62 the use of Eu3+ chelate-labeled analogues of melanin-concentrating hormone (MCH) as ligands for both

63 Melanin-concentrating hormone (MCH) has been known to be

64 Orexin and melanin-concentrating hormone (MCH) have been implicated

65 Ablation of neurons that express melanin-concentrating hormone (MCH) in adult Lep(ob/ob)

66 Melanin-concentrating hormone (MCH) is a 19-aa cyclic ne

67 Melanin-concentrating hormone (MCH) is a 19-amino-acid c

68 Melanin-concentrating hormone (MCH) is a cyclic 19-aa hy

69 Melanin-concentrating hormone (MCH) is a cyclic, nonadec

70 Melanin-concentrating hormone (MCH) is a hypothalamic ne

71 Melanin-concentrating hormone (MCH) is a hypothalamic ne

72 Melanin-concentrating hormone (MCH) is a hypothalamic pe

73 Melanin-concentrating hormone (MCH) is a neuropeptide hi

74 s of evidence indicate that the neuropeptide melanin-concentrating hormone (MCH) is an important comp

75 Melanin-concentrating hormone (MCH) is an orexigenic neu

76 Melanin-concentrating hormone (MCH) is expressed primari

77 Melanin-concentrating hormone (MCH) is implicated in the

78 Melanin-concentrating hormone (MCH) is involved in the r

79 Melanin-concentrating hormone (MCH) is produced mainly i

80 Neurons that synthesize melanin-concentrating hormone (MCH) may modulate arousal

81 orrelated with both neuropeptide Y (NPY) and melanin-concentrating hormone (MCH) mRNA.

82 Melanin-concentrating hormone (MCH) neurons and MCH-1 re

83 lateral hypothalamic (LH) circuits involving melanin-concentrating hormone (MCH) neurons are subject

84 tudy, we show that optogenetic activation of melanin-concentrating hormone (MCH) neurons during intak

85 (mGluR1 and mGluR5) activation on identified melanin-concentrating hormone (MCH) neurons was studied

86 Melanin-concentrating hormone (MCH) neurons, which are i

87 they are distinct from hypocretin/orexin and melanin-concentrating hormone (MCH) neurons.

88 s expression in orexinergic but not adjacent melanin-concentrating hormone (MCH) neurons; suggesting

89 amic neurons including those that synthesize melanin-concentrating hormone (MCH) or hypocretin/orexin

90 A molecular model of the human melanin-concentrating hormone (MCH) peptide was construc

91 Melanin-concentrating hormone (MCH) plays an essential r

92 n suggest that the hypothalamic neuropeptide melanin-concentrating hormone (MCH) regulates body weigh

93 Melanin-concentrating hormone (MCH) regulates feeding an

94 Melanin-concentrating hormone (MCH) regulates vital phys

95 The melanin-concentrating hormone (MCH) system is thought to

96 t fertility also upregulate the hypothalamic melanin-concentrating hormone (MCH) system that promotes

97 Melanin-concentrating hormone (MCH) was initially identi

98 The percentage of melanin-concentrating hormone (MCH)+/Fos+ neurons in the

99 Melanin-concentrating hormone (MCH), a conserved cyclic

100 Melanin-concentrating hormone (MCH), a cyclic 19-amino-a

101 e AcbSh contains high levels of receptor for melanin-concentrating hormone (MCH), a lateral hypothala

102 Melanin-concentrating hormone (MCH), a neuropeptide expr

103 ntibodies against tyrosine hydroxylase (TH), melanin-concentrating hormone (MCH), and hypocretin (Hcr

104 ontaining the feeding-related neuropeptides, melanin-concentrating hormone (MCH), and orexin (Orx).

105 ressin (AVP), histidine decarboxylase (HDC), melanin-concentrating hormone (MCH), and orexin/hypocret

106 rected to rWAT and iWAT expressed orexin and melanin-concentrating hormone (MCH), but male rats had a

107 eurons, and not nearby LH neurons expressing melanin-concentrating hormone (MCH), have mu-opioid rece

108 Ablation of the hypothalamic peptide, melanin-concentrating hormone (MCH), leads to a lean phe

109 oopiomelanocortin (POMC), orexin/hypocretin, melanin-concentrating hormone (MCH), thyrotropin-releasi

110 e distinct from neighboring leptin-regulated melanin-concentrating hormone (MCH)- or orexin (OX)-expr

111 Melanin-concentrating hormone (MCH)-deficient mice are h

112 Melanin-concentrating hormone (MCH)-expressing neurons h

113 Melanin-concentrating hormone (MCH)-producing neurons ar

114 detectable effect on neurons that synthesize melanin-concentrating hormone (MCH).

115 s, hypocretin (HCRT; also called orexin) and melanin-concentrating hormone (MCH).

116 elanocyte-stimulating hormone (alphaMSH) and melanin-concentrating hormone (MCH).

117 e VTA contain the hypothalamic neuropeptide, melanin-concentrating hormone (MCH).

118 ligand of this receptor is the neuropeptide melanin-concentrating hormone (MCH).

119 lamus of ob/ob mice encodes the neuropeptide melanin-concentrating hormone (MCH).

120 behaviour through the actions of orexin and melanin-concentrating hormone (MCH).

121 LH melanin-concentrating-hormone (MCH) and orexin/hypocreti

122 kefulness (orexin/hypocretin; OH), or sleep (melanin-concentrating hormone; MCH).

123 A novel series of melanin-concentrating hormone (MCH1) receptor antagonist

124 hypothalamic neuropeptides, hypocretin-1 and melanin-concentrating hormone, measured in the human amy

125 greatly increases Agouti-related peptide and melanin-concentrating hormone mRNA expression.

126 ght to moderate inputs arose from orexin and melanin concentrating hormone neurons, but cholinergic o

127 nd a lack of effect on leptin sensitivity of melanin concentrating hormone neurons.

128 Glut4 neuron ablation affects orexigenic melanin-concentrating hormone neurons but has limited ef

129 in gene transfer into the striatum or in the melanin-concentrating hormone neurons in the ZI or LH ha

130 excitatory current with repeated coexposure (melanin-concentrating hormone neurons), synergistic dire

131 Neither rPP nor NPY stimulated c-Fos in melanin-concentrating hormone neurons, but both activate

132 erifornical hypothalamic area, few contained melanin-concentrating hormone or orexin.

133 rons and/or fibers in this area positive for melanin concentrating hormone, oxytocin, arginine vasopr

134 ons and contain dopamine, histamine, orexin, melanin-concentrating hormone, oxytocin, and vasopressin

135 , agouti-related peptide, hypocretin/orexin, melanin-concentrating hormone, oxytocin, arginine vasopr

136 Expression of transcripts for human pro-melanin concentrating hormone (pMCH) were studied in the

137 ve (Orx(+)), whereas none were identified as melanin-concentrating hormone-positive.

138 kappaOR colocalizes with melanin concentrating hormone receptor 1 (MCH-R1) in the

139 otypes of mice with targeted deletion of the melanin concentrating hormone receptor 1 (MCH1-R).

140 A novel series of melanin concentrating hormone receptor 1 (MCHr1) antagon

141 -2-o ne (7) is a potent, orally bioavailable melanin concentrating hormone receptor 1 (MCHr1) antagon

142 mitogen-activated protein kinase 7 (MAPK7), melanin concentrating hormone receptor 1 (MCHR1), and sp

143 of multiple structurally distinct series of melanin concentrating hormone receptor 1 antagonists in

144 ormation but disrupts normal localization of melanin concentrating hormone receptor 1 to ciliary memb

145 ioselective synthesis of SNAP-7941, a potent melanin concentrating hormone receptor antagonist, was a

146 Melanin-concentrating hormone receptor 1 (MCH-R1) is a G

147 We identified the consensus sequence in melanin-concentrating hormone receptor 1 (Mchr1) and con

148 screening mode to triage multiple classes of melanin-concentrating hormone receptor 1 (MCHr1) antagon

149 DNA phage-display library, we identified the melanin-concentrating hormone receptor 1 (MCHR1) as a no

150 of somatostatin receptor type 3 (Sstr3) and melanin-concentrating hormone receptor 1 (Mchr1) in neur

151 The melanin-concentrating hormone receptor 1 (MCHR1) is a G

152 n of a high-throughput screening hit against melanin-concentrating hormone receptor 1 (MCHr1) led to

153 Deletion derivatives of melanin-concentrating hormone receptor 1 complementary D

154 The [35S]-labeled melanin-concentrating hormone receptor 1 derivatives wer

155 ts exhibited autoantibodies to more than one melanin-concentrating hormone receptor 1 epitope indicat

156 identification of autoantibodies against the melanin-concentrating hormone receptor 1 in patients wit

157 ediction of the potential B cell epitopes on melanin-concentrating hormone receptor 1 revealed that t

158 In this study, the B cell epitopes on melanin-concentrating hormone receptor 1 that are recogn

159 stence of multiple antibody binding sites on melanin-concentrating hormone receptor 1, including regi

160 Melanin-concentrating hormone receptor antagonists conta

161 are potent but nonspecific ligands for human melanin-concentrating hormone receptors 1 and 2 (hMCH-1R

162 s a potent but nonselective agonist at human melanin-concentrating hormone receptors 1 and 2 (hMCH-1R

163 e neighbors include opioid, somatostatin and melanin-concentrating hormone receptors.

164 a nonselective natural ligand for the human melanin-concentrating hormone receptors: hMCH-1R and hMC

165 by alpha-melanocyte-stimulating hormone and melanin-concentrating hormone, respectively.

166 altered mRNA expression levels of orexin and melanin-concentrating hormone, two peptides that are imp

167 Hypocretin, melanin concentrating hormone, tyrosine hydroxylase, neu