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1 igh potency and wash resistance (an index of membrane anchoring).
2 naling by liberating EGFR ligands from their membrane anchor.
3 -Bbp1 complex is the central unit of the SPB membrane anchor.
4 rane domain, an ectodomain, and a C-terminal membrane anchor.
5 hat provides a cytosolic domain and a plasma membrane anchor.
6 n carried out largely on atlastins lacking a membrane anchor.
7 e role of this substructure as a hydrophobic membrane anchor.
8 ytoplasmic tail of the Heart of glass (HEG1) membrane anchor.
9 ique N-terminal alpha-helix that serves as a membrane anchor.
10 phatidylinositol 3-phosphate (PI3P)-specific membrane anchor.
11 rate that in C. crescentus, FzlC is one such membrane anchor.
12 e with barriers for membrane exit due to the membrane anchors.
13 ows us to estimate the area density of these membrane anchors.
14 al proteins that use hydrophobic residues as membrane anchors.
15 binding constant of soluble proteins without membrane anchors.
16 hile the nonspecific interactions are mainly membrane-anchored.
17 d the Sec17 apolar loop has functions beyond membrane anchoring.
18 GARP has been assumed to require membrane anchoring.
19 oteins that regulate its activity and plasma membrane anchoring.
23 the C-terminal cytosolic tail of RHD3 has a membrane anchoring ability that is required for efficien
27 N-terminal helical segment having a role of membrane anchor, an unstructured C-terminal region that
29 ive amino acids N-terminal to the C-terminal membrane anchor and at a gamma-like site in the middle o
31 e molecular entity that serves as the plasma membrane anchor and the possible mechanism of regulated
32 Photolysis releases the bioagent from its membrane anchor and thereby renders it biologically acti
33 s confirm that the combined functionality of membrane anchoring and microtubule tip affinity is in pr
34 residues resulted in significant loss of PLB membrane anchoring and mislocalization to the cytoplasm
37 is an unusual membrane glycoprotein with two membrane anchors and an extended coiled-coil ectodomain.
42 ged residues, which is strictly required for membrane anchoring, and when transferred to the cytoplas
43 ifications are able to act as more than just membrane anchors, and dynamic S-acylation in particular
46 ociated ubiquitin-conjugating enzyme and its membrane anchor are both mutated, suggesting that matrix
49 csA is the catalytically active subunit, the membrane-anchored BcsB subunit is essential for catalysi
50 utocatalysis severs the protein into a large membrane-anchored beta subunit that noncovalently associ
52 linked glycans, glycosylphosphatidylinositol membrane anchors, beta1,3- and beta1,6-linked glucans, a
54 337-Gly340, Thr343, and Thr345) could act as membrane anchor, binding interface for a second rhodopsi
56 ocation channel as a weakly self-interacting membrane anchor but establishes a heteromeric TM-TM heli
57 membrane proteins do not merely function as membrane anchors but play active roles in many important
58 ontain a beta barrel domain that serves as a membrane anchor, but the assembly and quality control of
60 The FtsZ GTPase domain is separated from its membrane-anchoring C-terminal conserved (CTC) peptide by
66 tissue injury by physical separation of the membrane-anchored cofactor tissue factor (TF) from inact
67 regulated by the proteolytic activity of the membrane-anchored collagenases, MT1-, MT2-, and MT3-matr
68 ucleate actin filaments colocalize in plasma membrane-anchored complexes called nodes in the constric
69 lex glycolipid, lipid A, which serves as the membrane anchor component of lipopolysaccharide (LPS) an
71 f of concept, the mechanism of action of the membrane-anchored cytochrome P450 reductase (POR) is stu
72 erminal calpain protease is regulated by the membrane-anchored DEK1 MEM, which is connected to the ca
73 dophilin B2-plectin 1 complex functions as a membrane-anchoring device organizing and stabilizing the
74 tein engineering technology called MAD-TRAP (membrane-anchored display for Tat-based recognition of a
76 most relevant avenues and accomplishments of membrane-anchored DNA nanostructures for investigating,
78 by a 'glycan', which is preassembled onto a membrane-anchored dolichol molecule embedded within the
82 uence located between its Bcl-2 homology and membrane anchor domains and blocks homo- and heteromeric
84 on occurs at cysteine residues juxtaposed to membrane-anchoring domains such as transmembrane helices
86 ith Bag1 then shifts hERG degradation to the membrane-anchored E3 ligase TRC8 and its E2-conjugating
87 VSV vectors (N4CT1-EBOVGP1), which expresses membrane-anchored EBOV GP from the first position in the
94 ver, more recent work has suggested that the membrane-anchored epithelial cell serine protease matrip
95 arbohydrate-carbohydrate interaction between membrane-anchored epitopes derived from the marine spong
96 subtilis grows without FtsA or the putative membrane anchor EzrA and why bacteria lacking FtsA conta
97 and the membrane; in the active state, with membrane-anchored farnesyl and unrestrained HVR, the cat
99 in has a globular head that is attached to a membrane-anchored flexible stalk of approximately 80 res
101 Our characterization of FzlC as a novel membrane anchor for FtsZ expands our understanding of Ft
104 ) are functionally important glycolipids and membrane anchors for cell wall lipoglycans in the Coryne
108 fluenza virus type 1 (rHPIV1) expressing the membrane-anchored form of EBOV glycoprotein GP, as an in
110 mor surveillance functions when expressed in membrane-anchored form on activated immune effector cell
111 ectodomain should allow reengineering of the membrane anchoring from a native N-terminal to an artifi
112 f FtsZ regulators and establishes a role for membrane-anchored FtsZ in the regulation of cell wall hy
113 cherichia coli; (ii) in vitro AC assays with membrane-anchored full-length human AC and recombinant B
115 e show that WNT5A stimulates dimerization of membrane-anchored FZD4 CRDs and oligomerization of full-
117 in 2 to a GPR27V2 chimera in the presence of membrane-anchored G protein-coupled receptor kinase-2.
118 nsertion of peripheral proteins by using the membrane anchor (gamma-carboxyglutamic-acid-rich domain;
122 udies have revealed that nicastrin, a type I membrane-anchored glycoprotein, plays a role in gamma-se
123 n of the human enzyme lacking its N-terminal membrane anchor has allowed for physical and biochemical
125 screening, these antibodies are expressed as membrane-anchored IgM (mIgM) in 293F indicator cells.
126 inct mechanisms: classic signaling using the membrane-anchored IL-6 receptor and trans-signaling usin
127 ns, two amphipathic helices, and an in-plane membrane anchor in IL-26, which are structural features
129 lts provide new evidence for the role of the membrane anchor in PrP-lipid interactions, highlighting
130 -energy profile for the position of the syb2 membrane anchor in the membrane was determined using umb
133 the signal peptide of Gp3 does not act as a membrane anchor, indicating that it is completely transl
135 The glycosyl-phosphatidylinositol (GPI) membrane anchor is also not absolutely required for LON-
138 in vivo delivery of a corresponding soluble membrane anchored ligand, we generated lipidated analogs
144 ain reveals a beta-prism fold, a hydrophobic membrane-anchoring loop, and an electropositive phosphoi
146 LpoA structures helped explain how an outer membrane-anchored LpoA can either withdraw from or exten
149 thought to depend on the mobilization of the membrane-anchored matrix metalloproteinases MMP14 (MT1-M
150 elaxed lipid density; therefore this type of membrane anchor may assist in keeping the Z ring positio
151 e test the hypothesis that the length of the membrane anchor may impact the outcome by comparing sing
152 Although Fis1 is dispensable for fission, membrane-anchored Mdv1, Mff, or MiDs paired individually
154 have attached mucus as they did not shed the membrane-anchored meprin beta into the luminal mucus.
155 codes a protein with two distinct domains: a membrane-anchored metal ion permease and a diphtheria to
156 ntegrin And Metalloprotease (ADAM) family of membrane-anchored metalloproteases are synthesized as pr
158 ial regulator of cell-cell interactions, the membrane-anchored metalloproteinase ADAM17, in endochond
159 demonstrate that conditional deletion of the membrane-anchored metalloproteinase MT1-MMP (Mmp14) in m
160 ntegrin and metalloproteinase 17 (ADAM17), a membrane-anchored metalloproteinase that regulates epide
163 of recombinant protein variants lacking the membrane-anchored MHYT domain support NbdA being an acti
164 sults are consistent with a model in which a membrane anchored MinC/MinD complex is targeted to the Z
165 8, MMP-2, MMP-9, or MT1-MMP, we identify the membrane-anchored MMP, MT1-MMP, as the dominant collagen
166 We reason that the transport efficiency of membrane-anchored motors is reduced because of their sli
168 s (MMPs) are a family of secreted soluble or membrane-anchored multimodular peptidases regularly foun
169 ively, these findings indicate that MyoB are membrane-anchored myosin receptors that define a distinc
172 neuronal gangliosides is due to the C18 acyl membrane anchor of CerS1-derived precursor ceramides.
174 its role in the biosynthesis of lipid A, the membrane anchor of lipopolysaccharide (LPS), has not bee
175 ents of the bacteria, including lipid A, the membrane anchor of lipopolysaccharide, could affect any
178 decyl phosphocholine micelles to solvate the membrane anchor of the protein and the hydrophobic tail
179 hai3 on cell membranes and that constitutive membrane anchoring of GIV in yeast cells or rapid membra
181 uestions, we developed a system to mimic the membrane anchoring of Rho GTPases by creating liposomes
182 pecifically induce BPL cell apoptosis due to membrane anchoring of sTRAIL and simultaneous activation
184 CaaX motif (class B), which is important for membrane anchoring of the protein; the presence of such
186 established when the palmitoylation-mediated membrane-anchor of the STREX insert was removed by eithe
187 ting the dynamics and thermodynamics of this membrane anchor on a POPC bilayer using all-atom, explic
189 nation is within the cell envelope as either membrane-anchored or cell wall-anchored proteins, wherea
190 ed two novel mouse models, expressing either membrane-anchored or nonanchored versions of the human A
192 sion of the K2 C terminus as an extension of membrane-anchored P-selectin glycoprotein ligand-1 (PSGL
194 ic enzymes that catalyze depalmitoylation of membrane-anchored, palmitoylated H-Ras and growth-associ
195 ECAM) is a approximately 180-kDa multidomain membrane-anchored pan-peptidase inhibitor, which is clea
198 entirely dependent on CD4 anchoring, not on membrane anchoring per se, and required optimal Ab geome
200 ity and liberation of the YtgR domain from a membrane-anchored permease in C. trachomatis could repre
201 ividing cells expand their PG layer by using membrane-anchored PG synthases, which are guided by dyna
202 ha(0) are required for selective cleavage of membrane-anchored portions of the HCV polyprotein and fo
203 le's syndrome are irreversibly stimulated by membrane-anchored proteases (MAPs) and furin-like conver
206 Semaphorin 7a is a glycophosphatidylinositol membrane-anchored protein that promotes attachment and s
207 esent genetic evidence that a putative inner membrane-anchored protein with a large periplasmic domai
208 ied in the cytoplasmic N-terminal end of the membrane-anchored protein YfgM of Escherichia coli.
214 e approach enables isolation of integral and membrane anchored proteins and is also applicable follow
218 Adam10), a member of the ADAM family of cell membrane-anchored proteins, has been linked to the regul
219 e membrane-associated, involving a myriad of membrane-anchored proteins, proteomic efforts to better
220 bunits of voltage-gated calcium channels are membrane-anchored proteins, which are highly glycosylate
227 risingly, we identified here dimerization of membrane anchored Ras by combining attenuated total refl
229 d by the IL1RL1 gene, is expressed as both a membrane-anchored receptor (ST2L) activated by IL33 and
230 d sensitively on the binding constant of the membrane-anchored receptor and ligand proteins that medi
234 des in this network are myosins XI and their membrane-anchored receptors (MyoB) that, together, drive
236 igned a membrane 'staple', which consists of membrane-anchored repeats of the trans-aggregating FM do
240 and refine the NMR measurements on the Htt17 membrane anchor segment of huntingtin that is of fundame
241 their hydrophobic N-terminal polymerization/membrane anchor segment with the major pilins but are mu
242 both the hydrophobic signal sequence and the membrane anchor sequence promoting translocation of the
254 ur knowledge of non-proteolytic functions of membrane-anchored serine proteases and provides unexpect
255 biochemical observations regarding these two membrane-anchored serine proteases and their downstream
257 n, however, has focused on the potential for membrane-anchored serine proteases to regulate PAR activ
258 e showed that BACE1 can effectively shed the membrane-anchored signaling molecule Jagged 1 (Jag1).Wea
259 r chemically controlling cell adhesion using membrane-anchored single-stranded DNA oligonucleotides.
260 ull-length complexin-I binds more tightly to membrane-anchored SNARE complex than Cpx26-83, and it is
261 elix and an inhibitory helix (Cpx26-83) from membrane-anchored SNARE complex under equilibrium condit
263 on its own interferes with the zippering of membrane-anchored SNARE complexes midway through the zip
265 ydrogenase that lacks a typical cytochrome b membrane anchor subunit, which transfers electrons to th
266 ains unclear if R7BP serves exclusively as a membrane anchoring subunit or further modulates RGS prot
267 rt that RGS7 is selectively modulated by its membrane anchoring subunit R7BP, which sets the dynamic
269 eared to be secreted and Mmp2 appeared to be membrane-anchored, suggesting that protein localization
272 gand recognition by this enigmatic family of membrane-anchored TGF-beta family signaling regulators a
274 geted to the plasma membrane by a C-terminal membrane anchor that comprises a farnesyl-cysteine-methy
276 ChE is anchored at the TSC by a proline-rich membrane anchor, the small transmembrane protein anchor
279 e results indicate that being more than just membrane anchors, TM helices could play an important rol
280 is of fundamental importance: it serves as a membrane anchor to control the localization of huntingti
281 red in the crystal structure, functions as a membrane anchor to increase the effective EIIA(Glc) conc
283 of a protein, releasing the active form of a membrane-anchored transcription factor (MTF) or a membra
284 t, which together produce translocation of a membrane-anchored transcription factor to the nucleus to
286 cated form of the Rieske protein lacking the membrane anchor (trunc-TtRp) to investigate redox-state-
288 ly two MMPs-one secreted type (Mmp1) and one membrane-anchored type (Mmp2)-to study the function and
290 nce its discovery in the mid-1980s, the cell membrane-anchored urokinase-type plasminogen activator r
291 omposed of cytosolic V1-sector and lysosomal membrane-anchored V0-sector, regulates lysosomal acidifi
292 le CX3CL1 isoform, suggesting that it is the membrane-anchored version of CX3CL1 that regulates micro
293 ht to determine the relative contribution on membrane-anchored versus soluble CX3CL1 in regulating th
296 e, Rv3645, as a reporter enzyme in which the membrane anchor was substituted by the Escherichia coli
297 ntly, structure and orientation of the Htt17 membrane anchor were determined using a combined solutio
298 The Psd1 beta-subunit (Psd1beta) forms the membrane anchor, which binds the intermembrane space-loc
300 scherichia coli interaction of FtsZ with its membrane anchors, ZipA and FtsA, as well as the spatial
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