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1 lasmic membrane fusion protein, and an outer membrane channel.
2 f the tetrameric amantadine-blocked M2 trans-membrane channel.
3 9 and Toc34, as well as Toc75, a beta-barrel membrane channel.
4 n reported to be a swelling-activated plasma membrane channel.
5 activation of a specific inner mitochondrial membrane channel.
6  of anions through SLAC, a phospho-activated membrane channel.
7  in protein translocation through the SecYEG membrane channel.
8 ane fusion protein; and a beta-barrel, outer membrane channel.
9 ening and closing of this beta-barrel, outer membrane channel.
10 ning Sec signal sequences through the SecYEG membrane channel.
11 cators, VopB2 and VopD2, that constitute the membrane channel.
12 d is ultimately eliminated through the outer membrane channel.
13 ffusion and does not require facilitation by membrane channels.
14 l transduction from the stores to the plasma membrane channels.
15 of VacA was dependent on its ability to form membrane channels.
16 an either potentiate or inhibit a variety of membrane channels.
17  key transport characteristics of biological membrane channels.
18 hat modulate the function of these important membrane channels.
19 hout major effects on other gap junctions or membrane channels.
20 cessary for the formation of anion-selective membrane channels.
21 eric structures and can form anion-selective membrane channels.
22 ed the capacity of each mutant toxin to form membrane channels.
23 movement of water through aquaporin-4 (AQP4) membrane channels.
24 a toxin, VacA, that can form anion-selective membrane channels.
25 ependent on the formation of anion-selective membrane channels.
26 assembly and the incorporation of functional membrane channels.
27 phages also exploit chromosome-encoded outer membrane channels.
28 enhancement of calcium influx through plasma membrane channels.
29 obalt exerted a nonspecific effect on glomus membrane channels.
30 ins which function as regulatory subunits of membrane channels.
31 n increases the number of functional surface membrane channels.
32 oproteins (Panx1, -2, and -3) forming single membrane channels.
33 ucting cells by stably expressing only three membrane channels.
34 obvious in studies of ion permeation through membrane channels.
35 etween inner membrane transporters and outer membrane channels.
36 s and it does not occur through recycling of membrane channels.
37 ondence of R(h) and R(p), the pore radius of membrane channels: a polymer such as PEG diffuses with i
38 ng ion channels (ASICs) are cation-selective membrane channels activated by H(+) binding upon decreas
39 y (CCE), the influx of Ca(2+) through plasma membrane channels activated in response to depletion of
40 own to inhibit cellular vacuolation and VacA membrane channel activity also inhibit cytochrome c rele
41 hanism dependent on cellular entry and toxin membrane channel activity.
42 roteins and regulates endolysosome-localized membrane channel activity.
43 pecific characteristics among the large pore membrane channels; an open (hemi)channel is not a nonsel
44 toplasmic and outer membranes, with an outer membrane channel and a periplasmic adaptor protein, and
45 sional structure for the trimeric CusC outer membrane channel and developed a model of the tripartite
46  the interaction between a voltage-dependent membrane channel and eNOS may be important for regulatin
47 e recent discovery that human SAA1.1 forms a membrane channel and have important implications for und
48 cture is the largest determined for an outer-membrane channel and is unprecedented in being composed
49 of voltage-dependent anion channel (VDAC), a membrane channel and NADH oxidase, as a cause of early m
50 ey periplasmic interaction between the outer membrane channel and the adaptor protein in the assemble
51 s: the inner membrane transporter, the outer membrane channel and the periplasmic lipoprotein.
52  in response to Ca(2+) influx through plasma membrane channels and Ca(2+) release from intracellular
53 ity is limited by the kinetics of the neuron membrane channels and can be stopped by brief inhibitory
54  variables such as the relative abundance of membrane channels and channel kinetic rates.
55 nels has two components: a reduced number of membrane channels and decreased potentiation of the rema
56 nalize the role of hDlg in the clustering of membrane channels and formation of multiprotein complexe
57  form a large and widespread family of outer membrane channels and have been implicated in the uptake
58 dherins, cell adhesion molecules, receptors, membrane channels and other transmembrane proteins.
59 a disproportionate percentage of cytoplasmic membrane channels and outer-membrane porins.
60 both the ionic current and fluorescence from membrane channels and pores has the potential to link st
61 es in the synthesis and assembly of designed membrane channels and pores include addressable template
62 s, direct interaction with and modulation of membrane channels and proteins, regulation of gene expre
63  spectrin-actin-based cytoskeleton, integral membrane channels and receptors, and membrane-associated
64 teractions with proteins, in particular with membrane channels and receptors.
65 in opposition to influx through other plasma membrane channels and release from stores.
66 from the extracellular medium through plasma membrane channels and that the second and third elevatio
67 lly, the function of a variety of additional membrane channels and transporters is altered by pH vari
68                         In GPCRs, as well as membrane channels and transporters, amino acid residues
69 sets compartment-specific activity codes for membrane channels and transporters.
70                             TolC is an outer membrane channel, and AcrA is an elongated lipoprotein t
71  diffuses with its long axis parallel to the membrane channel, and passes through the channel without
72  lipid destabilization, activation of native membrane channels, and aggregation of Abeta into Ca(2+)-
73 ric structures, formation of anion-selective membrane channels, and entry of VacA into host cells.
74 tructure categories, including cytoskeleton, membrane channels, and extracellular region.
75 simulated data of a tetrameric alpha-helical membrane channel (Aquaporin-0) solubilized by n-Dodecyl
76 ysiological studies of presumed TRPML plasma membrane channels are contradictory and inconsistent wit
77 me glutamate receptor subunits of ionotropic membrane channels are edited by site-specific base-deami
78                                        These membrane channels are heteromeric complexes that compris
79                       While the gap junction membrane channels are recognizable in negatively stained
80 ilable data on native STIM2-regulated plasma membrane channels are scarce.
81                                              Membrane channels are subject to a wide variety of regul
82 mp consists of a soluble ATPase (ArsA) and a membrane channel (ArsB).
83 et electric field falls primarily across the membrane channel, as expected for two conductive baths s
84 equence that define solution aggregation and membrane channel assembly.
85 nd should be useful in the de novo design of membrane channels both for basic studies of ion permeati
86 ton transfer in the SS dimer is probably the membrane-channel/bulk solution interface.
87 roposed to measure the water permeability of membrane channels by means of molecular dynamics simulat
88  nanotubes can provide a simplified model of membrane channels by reproducing these critical features
89 olar water movement is largely controlled by membrane channels called tonoplast-intrinsic aquaporins
90 hat the conductance of a mitochondrial inner membrane channel, called MCC, was specifically blocked b
91  the recent discovery that tension-sensitive membrane channels can catalyze the conversion of the ina
92                                 Thus, double-membraned channels can be induced by expression of recom
93 Intercellular communication via gap junction membrane channels cannot occur until two apposing hemich
94 rstanding of key process constraints such as membrane channel clogging, and of the science of membran
95      Here, we use a biophysical model of the membrane-channel complex to analyze the nature of the ga
96                  TolC functions as the outer membrane channel component for both type I secretion and
97                            TolC is the outer membrane channel component used by the type I secretion
98  T-DNA substrate is delivered from the inner membrane channel components VirB6 and VirB8 to periplasm
99 visiae triggers Ca2+ influx through a plasma membrane channel composed of Cch1 and Mid1.
100 mbrane and, in some manner, activates plasma membrane channels comprising Orai1, -2, and -3 subunits.
101 -nitrosylation, we tested whether CNs affect membrane channel conductance directly in neurons isolate
102 rm sensors derives from voltage-gated Ca(2+) membrane channels configured such that an increase in te
103 roteins; comparison of transporter and outer membrane channel contents from different organisms; know
104 he inner-membrane efflux pump CusA and outer-membrane channel CusC to mediate resistance to Cu(+) and
105 ty to ubiquitylate ENaC and increases apical membrane channel density by reducing its endocytosis.
106 n during maintained stimulation, and reduced membrane channel density causes hyperexcitability.
107 ingly heterogeneous group of primary cardiac membrane channel diseases.
108 ic complexes capable of cross-linking plasma membrane channels (e.g. metabotropic glutamate receptor)
109 brane fusion protein (MFP) family; and outer membrane channels exemplified by the Escherichia coli To
110 t in a pro-inflammatory state, a decrease in membrane channel expression leading to reduced Slack-med
111 tive in the capacity to form anion-selective membrane channels fail to cause clustering and redistrib
112 ) is a member of the Major Intrinsic Protein membrane channel family.
113  member of the major intrinsic protein (MIP) membrane channel family.
114 bearing deletions of opmH, encoding an outer membrane channel for efflux substrates, and four efflux
115  and Moore indirectly supports the idea of a membrane channel for potassium conductance.
116        Glucose transporters form specialized membrane channels for the transport of sugars into and o
117                                  Many plasma membrane channels form oligomeric assemblies, and hetero
118  whether these GXXXG motifs are required for membrane channel formation and cytotoxicity and to clari
119               The p33 domain is required for membrane channel formation and intracellular toxic activ
120 s, whereas mutant VacA proteins defective in membrane channel formation do not.
121  and cytotoxicity and to clarify the role of membrane channel formation in the biological activity of
122 , and they also provide strong evidence that membrane channel formation is essential for VacA cytotox
123 hydrophobic region of VacA are essential for membrane channel formation, and they also provide strong
124 semble into oligomeric structures capable of membrane channel formation.
125 e for the p33 domain, which is essential for membrane channel formation.
126 brane proteins require ribosome binding to a membrane channel formed by the Sec61p complex.
127                                     However, membrane channels formed by type s1 VacA and type s2 Vac
128 action of the cytoplasmic SecA ATPase with a membrane channel, formed by the heterotrimeric SecY comp
129        These peptides exhibit antibiotic and membrane channel-forming activities.
130 d G14A) that ablate vacuolating activity and membrane channel-forming activity render VacA unable to
131 abolites is believed to be based in an outer membrane, channel-forming protein known as VDAC (voltage
132 o change the electrical characteristics of a membrane channel from linear to rectifying.
133 uded are those involved in chemotaxis, outer membrane channel function, degradation of aromatic ring
134 sed by deletion of the multifunctional outer membrane channel gene tolC.
135               Pannexin 1 (Panx1) is a plasma membrane channel glycoprotein that plays a role in innat
136 er-selective pathway through the aquaporin-1 membrane channel has been visualized by fitting an atomi
137                              This stabilized membrane channel has little evolutionary precedent.
138 ositol trisphosphate, cellular ion pumps and membrane channels has become more clearly understood, in
139                             According to the membrane channel hypothesis of carotid body O2 chemorece
140 essing cells showed many cell surface double-membraned channels, immunogold SR-BI, apolipoprotein (HD
141              We conclude that AQP9 serves as membrane channel in hepatocytes for glycerol and urea at
142  results show that PC2 functions as a plasma membrane channel in renal epithelia and suggest that PC2
143     Type s1/m1 VacA from strain 60190 formed membrane channels in a planar lipid bilayer assay at a s
144                   Nanopores also function as membrane channels in all living systems, where they serv
145                                       Plasma membrane channels in embryonic cones have a high turnove
146                               It forms ionic membrane channels in fungal cells.
147  cytoplasmic membrane transporters and outer membrane channels in organisms whose complete genome seq
148                                      Certain membrane channels including acetylcholine receptors, gap
149           Pannexin-1 (Panx1) is a large-pore membrane channel involved in the release of ATP and othe
150 reticulum, although Ca(2+) influx via plasma membrane channels is also necessary to sustain the oscil
151                     The flow of ions through membrane channels is precisely regulated by gates.
152                   TolC, which forms an outer membrane channel, is an essential component of several e
153 iple factors, including K conductance across membrane channels, K driving force as reflected by the t
154  drive many cellular processes, ranging from membrane channel kinetics to transcriptional regulation,
155                      All mitochondrial outer membrane channels known to date are beta-barrel membrane
156 med by VacA6-27, a mutant that fails to form membrane channels, lack an organized p33 central core.
157 growth factors increase the number of plasma membrane channels may involve stabilizing them in the pl
158 atives that are excluded from other types of membrane channels may provide molecules with connexin-sp
159 ellular Ca2+ release channels, T-type plasma membrane channels may regulate cell growth.
160                                 Gap junction membrane channels mediate electrical and metabolic coupl
161 ively, these data identify PANX1 as a plasma membrane channel mediating the regulated release of find
162   To remove these toxic ions, the CusC outer membrane channel must form a beta-barrel structural doma
163 -stimulated ENaC open probability and apical membrane channel number.
164      VopQ forms a nonspecific, voltage-gated membrane channel of 18 A resulting in neutralization of
165 e in chloroplast biogenesis in plants as the membrane channel of the protein import translocon at the
166  set of membrane transport systems and outer membrane channels of each organism are annotated based o
167                     Substrate-specific outer membrane channels of gram-negative bacteria mediate upta
168 ssion properties, LTD, and calcium-activated membrane channels of hippocampal CA1 pyramidal neurons i
169  in the brain, and can have rapid actions on membrane channels of neurons.
170 s, most notably diverse TonB-dependent outer membrane channels of unknown substrate specificity.
171 ied the effect of the Escherichia coli outer membrane channel OmpF on the accumulation of the fluoroq
172       The question of how mechanically gated membrane channels open and close is notoriously difficul
173 iption of this "Ca2+ store release to plasma membrane channel opening" link, but to our knowledge the
174 s involves functional homomeric TRPM6 plasma membrane channels or heteromeric channel assemblies with
175 lycosylation may play a role in the neuronal membrane channels or networks involved in the physiology
176 nd to the cytoplasmic domains of a number of membrane channels or receptors.
177 s but on SNAP-25, probably via exocytosis of membrane channels or regulatory molecules.
178 e expression, impair formation of functional membrane channels, or alter channel conductance.
179                 Here, we identify the plasma membrane channel pannexin 1 (PANX1) as a mediator of fin
180 mary macrophages, potassium ion flux and the membrane channel pannexin 1 have been suggested to play
181                Pannexin1 (Panx1) is a plasma membrane channel permeable to relatively large molecules
182 ersible linkage to SUMO silences K2P1 plasma membrane channels; phosphorylation of K2P3 enables 14-3-
183 orce microscopy (AFM) images 3D structure of membrane channels placed on a solid substrate.
184 , carbon nanotubes (CNTs) should be an ideal membrane channel platform: they exhibit excellent transp
185 Ryanodine receptors (RyRs) are intracellular membrane channels playing key roles in many Ca(2+) signa
186 nd regulated by HpUreI, a proton-gated inner membrane channel protein essential for gastric survival
187 d to study selectivity and regulation of the membrane channel protein GlpF and the enzyme glycerol ki
188 g 24 h exposure to chronic hypoxia (CH), and membrane channel protein levels were enhanced.
189  tuberculosis (Mtb) mutant lacking the outer membrane channel protein Rv1698 accumulated 100-fold mor
190 nts, an inner membrane transporter, an outer membrane channel protein, and a periplasmic protein, whi
191 ands have been identified that link titin to membrane channels, protein turnover and gene expression.
192                                              Membrane channel proteins are of great interest as pulse
193 glutamate receptors (GluRs) are ligand-gated membrane channel proteins found in the central neural sy
194  of a 191-base pair fragment associated with membrane channel proteins M1 and M2 of the influenza-A v
195                                              Membrane channel proteins of the aquaporin family are hi
196                            A large family of membrane channel proteins selective for transport of wat
197          Aquaporins (AQP) are water-specific membrane channel proteins.
198 ch tools against known transporter and outer membrane channel proteins; comparison of transporter and
199 ng), HlyD (membrane fusion), and TolC (outer membrane channel) proteins were identified.
200        Consistent with a mechanism of plasma membrane channel-PSD-95 binding, coexpression with PSD-9
201 stand the functional role of the peroxisomal membrane channel Pxmp2, mice with a targeted disruption
202 keleton controls the disposition of selected membrane channels, receptors, and transporters.
203  in either ACC2 or Tic20-IV, the chloroplast membrane channel required for ACC2 uptake.
204 re essential components of the putative VirB membrane channel required for transfer of the T-complex
205 predicted to be structurally similar to VacA membrane channels) reveals that p55 and the beta-helical
206 omprising at its core an ATPase, SecA, and a membrane channel, SecYEG, is responsible for the majorit
207                                 Ligand-gated membrane channels selectively facilitate the entry of ir
208      Because the chemical composition of the membrane-channel/solution interface is strikingly differ
209 ting step being in the channel and/or at the membrane-channel/solution interface, and not in bulk sol
210 f close contacts of the substrate with inner membrane channel subunits but blocked formation of conta
211 he molecular dynamics simulation of a simple membrane-channel system.
212 ynamics on anesthetic action in a simplified membrane-channel system.
213 h guanidinium groups, leading to a transient membrane channel that facilitates the transport of argin
214                          The PTP is an inner membrane channel that forms from F-ATPase, possessing a
215 lasmic reticulum, Orai1 (CRACM1) as a plasma membrane channel that is activated by the store-operated
216 electrocyte junction are best described by a membrane channel that meters transmitter from a presynap
217 xin hemichannels are Ca(2+)-permeable plasma membrane channels that are also controlled by [Ca(2+)](i
218  such as ion pumps, transporters, and plasma membrane channels that control guard cell turgor pressur
219 or intrinsic proteins (MIPs) are a family of membrane channels that facilitate the bidirectional tran
220                               Aquaporins are membrane channels that facilitate the flow of water acro
221 p (transient receptor potential) form plasma membrane channels that mediate Ca(2+) entry following th
222 ian homologues of Drosophila Trp form plasma membrane channels that mediate Ca(2+) influx in response
223                            Gap junctions are membrane channels that mediate electrical and metabolic
224 in 1 (PANX1) subunits form oligomeric plasma membrane channels that mediate nucleotide release for pu
225 tionally interacts with and activates plasma membrane channels that mediate store-operated Ca(2+) ent
226 ansporters) form a superfamily of pentameric membrane channels that translocate monovalent anions acr
227 ion through macromolecular associations with membrane channels that transport chloride, bicarbonate,
228 ry nerves, in particular their receptors and membrane channels; the plasticity of the pathways; and t
229                                          For membrane channels, this effect can alter the critical me
230 o the opening of another outer mitochondrial membrane channel through which cytochrome c can transit,
231 model for perforin (acting by forming a cell membrane channel through which granzymes pass) does not
232 ) and, therefore, should not be able to form membrane channels, thus eliminating this possible mechan
233 tes entry of external calcium through plasma membrane channels to affect immune cell activation.
234 is of the contribution of ion fluxes through membrane channels to changes of intracellular ion concen
235 ns at the outer membrane and includes a core membrane channel, Toc75, and two receptor proteins, Toc3
236                                    The outer membrane channel TolC is a key component of multidrug ef
237 he inner membrane transporter AcrB and outer membrane channel TolC is thought to be mediated by AcrA.
238 asmic membrane fusion protein, and the outer membrane channel TolC(HI).
239       This pump assembly comprises the outer-membrane channel TolC, the secondary transporter AcrB lo
240 cts were obtained in cells lacking the outer membrane channel TolC, which acts with AcrEF, suggesting
241 er AcrB of the RND superfamily and the outer membrane channel TolC.
242 in vivo function of MacAB requires the outer membrane channel TolC.
243 rter and establishes the link with the outer membrane channel TolC.
244 lar calcium to enter the cell through plasma membrane channels, too.
245 IcsA requires the SecA ATPase and the SecYEG membrane channel (translocon) for secretion.
246 y slaves to the levels of Ca2+ determined by membrane channels, transporters and exchangers, but are
247 f the transient receptor potential family of membrane channels (TRPC) have been implicated in the gen
248 DPR controls cation entry through the plasma membrane channel TRPM2.
249 t Bcl-x(L) maintains the outer mitochondrial membrane channel, VDAC, in an open configuration.
250 lls when synaptic transmission and intrinsic membrane channels were inoperative.
251                   Uncouplers and blockers of membrane channels were used to investigate the mechanism
252  for stabilizing interactions with the outer membrane channel, whereas TriB is important for the stim
253 re defective in formation of anion-selective membrane channels, whereas proteins containing G121R or
254 A, and G26A mutations formed anion-selective membrane channels, whereas VacA proteins containing P9A,
255 nifest the transient opening of nonselective membrane channels, which admits fluorescent indicators o
256 ing properties of bacterial mechanosensitive membrane channels, which are thought to confer osmoprote
257                                 These plasma membrane channels, which connect the cytoplasm of adjace
258 ermediate, the outer and inner mitochondrial membrane channels, which normally interact only transien
259 f the permeability transition pore, an inner membrane channel whose opening requires matrix Ca(2+) an
260  gap junctional channels, Panx1 forms single-membrane channels, whose functional role in neuronal cir
261 his structure identifies VirB10 as the outer-membrane channel with a unique hydrophobic double-helica
262 developing synthetic analogues of biological membrane channels with high efficiency and exquisite sel
263 f wild-type VacA and VacA-(Delta6-27) formed membrane channels with properties intermediate between t
264 nitude greater than any previously described membrane channel, with an average diameter of 340 nm and
265 t to subsequently be transported through the membrane channel without the interference of cytosolic b

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