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1 lasmic membrane fusion protein, and an outer membrane channel.
2 f the tetrameric amantadine-blocked M2 trans-membrane channel.
3 9 and Toc34, as well as Toc75, a beta-barrel membrane channel.
4 n reported to be a swelling-activated plasma membrane channel.
5 activation of a specific inner mitochondrial membrane channel.
6 of anions through SLAC, a phospho-activated membrane channel.
7 in protein translocation through the SecYEG membrane channel.
8 ane fusion protein; and a beta-barrel, outer membrane channel.
9 ening and closing of this beta-barrel, outer membrane channel.
10 ning Sec signal sequences through the SecYEG membrane channel.
11 cators, VopB2 and VopD2, that constitute the membrane channel.
12 d is ultimately eliminated through the outer membrane channel.
13 ffusion and does not require facilitation by membrane channels.
14 l transduction from the stores to the plasma membrane channels.
15 of VacA was dependent on its ability to form membrane channels.
16 an either potentiate or inhibit a variety of membrane channels.
17 key transport characteristics of biological membrane channels.
18 hat modulate the function of these important membrane channels.
19 hout major effects on other gap junctions or membrane channels.
20 cessary for the formation of anion-selective membrane channels.
21 eric structures and can form anion-selective membrane channels.
22 ed the capacity of each mutant toxin to form membrane channels.
23 movement of water through aquaporin-4 (AQP4) membrane channels.
24 a toxin, VacA, that can form anion-selective membrane channels.
25 ependent on the formation of anion-selective membrane channels.
26 assembly and the incorporation of functional membrane channels.
27 phages also exploit chromosome-encoded outer membrane channels.
28 enhancement of calcium influx through plasma membrane channels.
29 obalt exerted a nonspecific effect on glomus membrane channels.
30 ins which function as regulatory subunits of membrane channels.
31 n increases the number of functional surface membrane channels.
32 oproteins (Panx1, -2, and -3) forming single membrane channels.
33 ucting cells by stably expressing only three membrane channels.
34 obvious in studies of ion permeation through membrane channels.
35 etween inner membrane transporters and outer membrane channels.
36 s and it does not occur through recycling of membrane channels.
37 ondence of R(h) and R(p), the pore radius of membrane channels: a polymer such as PEG diffuses with i
38 ng ion channels (ASICs) are cation-selective membrane channels activated by H(+) binding upon decreas
39 y (CCE), the influx of Ca(2+) through plasma membrane channels activated in response to depletion of
40 own to inhibit cellular vacuolation and VacA membrane channel activity also inhibit cytochrome c rele
43 pecific characteristics among the large pore membrane channels; an open (hemi)channel is not a nonsel
44 toplasmic and outer membranes, with an outer membrane channel and a periplasmic adaptor protein, and
45 sional structure for the trimeric CusC outer membrane channel and developed a model of the tripartite
46 the interaction between a voltage-dependent membrane channel and eNOS may be important for regulatin
47 e recent discovery that human SAA1.1 forms a membrane channel and have important implications for und
48 cture is the largest determined for an outer-membrane channel and is unprecedented in being composed
49 of voltage-dependent anion channel (VDAC), a membrane channel and NADH oxidase, as a cause of early m
50 ey periplasmic interaction between the outer membrane channel and the adaptor protein in the assemble
52 in response to Ca(2+) influx through plasma membrane channels and Ca(2+) release from intracellular
53 ity is limited by the kinetics of the neuron membrane channels and can be stopped by brief inhibitory
55 nels has two components: a reduced number of membrane channels and decreased potentiation of the rema
56 nalize the role of hDlg in the clustering of membrane channels and formation of multiprotein complexe
57 form a large and widespread family of outer membrane channels and have been implicated in the uptake
60 both the ionic current and fluorescence from membrane channels and pores has the potential to link st
61 es in the synthesis and assembly of designed membrane channels and pores include addressable template
62 s, direct interaction with and modulation of membrane channels and proteins, regulation of gene expre
63 spectrin-actin-based cytoskeleton, integral membrane channels and receptors, and membrane-associated
66 from the extracellular medium through plasma membrane channels and that the second and third elevatio
67 lly, the function of a variety of additional membrane channels and transporters is altered by pH vari
71 diffuses with its long axis parallel to the membrane channel, and passes through the channel without
72 lipid destabilization, activation of native membrane channels, and aggregation of Abeta into Ca(2+)-
73 ric structures, formation of anion-selective membrane channels, and entry of VacA into host cells.
75 simulated data of a tetrameric alpha-helical membrane channel (Aquaporin-0) solubilized by n-Dodecyl
76 ysiological studies of presumed TRPML plasma membrane channels are contradictory and inconsistent wit
77 me glutamate receptor subunits of ionotropic membrane channels are edited by site-specific base-deami
83 et electric field falls primarily across the membrane channel, as expected for two conductive baths s
85 nd should be useful in the de novo design of membrane channels both for basic studies of ion permeati
87 roposed to measure the water permeability of membrane channels by means of molecular dynamics simulat
88 nanotubes can provide a simplified model of membrane channels by reproducing these critical features
89 olar water movement is largely controlled by membrane channels called tonoplast-intrinsic aquaporins
90 hat the conductance of a mitochondrial inner membrane channel, called MCC, was specifically blocked b
91 the recent discovery that tension-sensitive membrane channels can catalyze the conversion of the ina
93 Intercellular communication via gap junction membrane channels cannot occur until two apposing hemich
94 rstanding of key process constraints such as membrane channel clogging, and of the science of membran
98 T-DNA substrate is delivered from the inner membrane channel components VirB6 and VirB8 to periplasm
100 mbrane and, in some manner, activates plasma membrane channels comprising Orai1, -2, and -3 subunits.
101 -nitrosylation, we tested whether CNs affect membrane channel conductance directly in neurons isolate
102 rm sensors derives from voltage-gated Ca(2+) membrane channels configured such that an increase in te
103 roteins; comparison of transporter and outer membrane channel contents from different organisms; know
104 he inner-membrane efflux pump CusA and outer-membrane channel CusC to mediate resistance to Cu(+) and
105 ty to ubiquitylate ENaC and increases apical membrane channel density by reducing its endocytosis.
108 ic complexes capable of cross-linking plasma membrane channels (e.g. metabotropic glutamate receptor)
109 brane fusion protein (MFP) family; and outer membrane channels exemplified by the Escherichia coli To
110 t in a pro-inflammatory state, a decrease in membrane channel expression leading to reduced Slack-med
111 tive in the capacity to form anion-selective membrane channels fail to cause clustering and redistrib
114 bearing deletions of opmH, encoding an outer membrane channel for efflux substrates, and four efflux
118 whether these GXXXG motifs are required for membrane channel formation and cytotoxicity and to clari
121 and cytotoxicity and to clarify the role of membrane channel formation in the biological activity of
122 , and they also provide strong evidence that membrane channel formation is essential for VacA cytotox
123 hydrophobic region of VacA are essential for membrane channel formation, and they also provide strong
128 action of the cytoplasmic SecA ATPase with a membrane channel, formed by the heterotrimeric SecY comp
130 d G14A) that ablate vacuolating activity and membrane channel-forming activity render VacA unable to
131 abolites is believed to be based in an outer membrane, channel-forming protein known as VDAC (voltage
133 uded are those involved in chemotaxis, outer membrane channel function, degradation of aromatic ring
136 er-selective pathway through the aquaporin-1 membrane channel has been visualized by fitting an atomi
138 ositol trisphosphate, cellular ion pumps and membrane channels has become more clearly understood, in
140 essing cells showed many cell surface double-membraned channels, immunogold SR-BI, apolipoprotein (HD
142 results show that PC2 functions as a plasma membrane channel in renal epithelia and suggest that PC2
143 Type s1/m1 VacA from strain 60190 formed membrane channels in a planar lipid bilayer assay at a s
147 cytoplasmic membrane transporters and outer membrane channels in organisms whose complete genome seq
150 reticulum, although Ca(2+) influx via plasma membrane channels is also necessary to sustain the oscil
153 iple factors, including K conductance across membrane channels, K driving force as reflected by the t
154 drive many cellular processes, ranging from membrane channel kinetics to transcriptional regulation,
156 med by VacA6-27, a mutant that fails to form membrane channels, lack an organized p33 central core.
157 growth factors increase the number of plasma membrane channels may involve stabilizing them in the pl
158 atives that are excluded from other types of membrane channels may provide molecules with connexin-sp
161 ively, these data identify PANX1 as a plasma membrane channel mediating the regulated release of find
162 To remove these toxic ions, the CusC outer membrane channel must form a beta-barrel structural doma
165 e in chloroplast biogenesis in plants as the membrane channel of the protein import translocon at the
166 set of membrane transport systems and outer membrane channels of each organism are annotated based o
168 ssion properties, LTD, and calcium-activated membrane channels of hippocampal CA1 pyramidal neurons i
170 s, most notably diverse TonB-dependent outer membrane channels of unknown substrate specificity.
171 ied the effect of the Escherichia coli outer membrane channel OmpF on the accumulation of the fluoroq
173 iption of this "Ca2+ store release to plasma membrane channel opening" link, but to our knowledge the
174 s involves functional homomeric TRPM6 plasma membrane channels or heteromeric channel assemblies with
175 lycosylation may play a role in the neuronal membrane channels or networks involved in the physiology
180 mary macrophages, potassium ion flux and the membrane channel pannexin 1 have been suggested to play
182 ersible linkage to SUMO silences K2P1 plasma membrane channels; phosphorylation of K2P3 enables 14-3-
184 , carbon nanotubes (CNTs) should be an ideal membrane channel platform: they exhibit excellent transp
185 Ryanodine receptors (RyRs) are intracellular membrane channels playing key roles in many Ca(2+) signa
186 nd regulated by HpUreI, a proton-gated inner membrane channel protein essential for gastric survival
187 d to study selectivity and regulation of the membrane channel protein GlpF and the enzyme glycerol ki
189 tuberculosis (Mtb) mutant lacking the outer membrane channel protein Rv1698 accumulated 100-fold mor
190 nts, an inner membrane transporter, an outer membrane channel protein, and a periplasmic protein, whi
191 ands have been identified that link titin to membrane channels, protein turnover and gene expression.
193 glutamate receptors (GluRs) are ligand-gated membrane channel proteins found in the central neural sy
194 of a 191-base pair fragment associated with membrane channel proteins M1 and M2 of the influenza-A v
198 ch tools against known transporter and outer membrane channel proteins; comparison of transporter and
201 stand the functional role of the peroxisomal membrane channel Pxmp2, mice with a targeted disruption
204 re essential components of the putative VirB membrane channel required for transfer of the T-complex
205 predicted to be structurally similar to VacA membrane channels) reveals that p55 and the beta-helical
206 omprising at its core an ATPase, SecA, and a membrane channel, SecYEG, is responsible for the majorit
208 Because the chemical composition of the membrane-channel/solution interface is strikingly differ
209 ting step being in the channel and/or at the membrane-channel/solution interface, and not in bulk sol
210 f close contacts of the substrate with inner membrane channel subunits but blocked formation of conta
213 h guanidinium groups, leading to a transient membrane channel that facilitates the transport of argin
215 lasmic reticulum, Orai1 (CRACM1) as a plasma membrane channel that is activated by the store-operated
216 electrocyte junction are best described by a membrane channel that meters transmitter from a presynap
217 xin hemichannels are Ca(2+)-permeable plasma membrane channels that are also controlled by [Ca(2+)](i
218 such as ion pumps, transporters, and plasma membrane channels that control guard cell turgor pressur
219 or intrinsic proteins (MIPs) are a family of membrane channels that facilitate the bidirectional tran
221 p (transient receptor potential) form plasma membrane channels that mediate Ca(2+) entry following th
222 ian homologues of Drosophila Trp form plasma membrane channels that mediate Ca(2+) influx in response
224 in 1 (PANX1) subunits form oligomeric plasma membrane channels that mediate nucleotide release for pu
225 tionally interacts with and activates plasma membrane channels that mediate store-operated Ca(2+) ent
226 ansporters) form a superfamily of pentameric membrane channels that translocate monovalent anions acr
227 ion through macromolecular associations with membrane channels that transport chloride, bicarbonate,
228 ry nerves, in particular their receptors and membrane channels; the plasticity of the pathways; and t
230 o the opening of another outer mitochondrial membrane channel through which cytochrome c can transit,
231 model for perforin (acting by forming a cell membrane channel through which granzymes pass) does not
232 ) and, therefore, should not be able to form membrane channels, thus eliminating this possible mechan
233 tes entry of external calcium through plasma membrane channels to affect immune cell activation.
234 is of the contribution of ion fluxes through membrane channels to changes of intracellular ion concen
235 ns at the outer membrane and includes a core membrane channel, Toc75, and two receptor proteins, Toc3
237 he inner membrane transporter AcrB and outer membrane channel TolC is thought to be mediated by AcrA.
240 cts were obtained in cells lacking the outer membrane channel TolC, which acts with AcrEF, suggesting
246 y slaves to the levels of Ca2+ determined by membrane channels, transporters and exchangers, but are
247 f the transient receptor potential family of membrane channels (TRPC) have been implicated in the gen
252 for stabilizing interactions with the outer membrane channel, whereas TriB is important for the stim
253 re defective in formation of anion-selective membrane channels, whereas proteins containing G121R or
254 A, and G26A mutations formed anion-selective membrane channels, whereas VacA proteins containing P9A,
255 nifest the transient opening of nonselective membrane channels, which admits fluorescent indicators o
256 ing properties of bacterial mechanosensitive membrane channels, which are thought to confer osmoprote
258 ermediate, the outer and inner mitochondrial membrane channels, which normally interact only transien
259 f the permeability transition pore, an inner membrane channel whose opening requires matrix Ca(2+) an
260 gap junctional channels, Panx1 forms single-membrane channels, whose functional role in neuronal cir
261 his structure identifies VirB10 as the outer-membrane channel with a unique hydrophobic double-helica
262 developing synthetic analogues of biological membrane channels with high efficiency and exquisite sel
263 f wild-type VacA and VacA-(Delta6-27) formed membrane channels with properties intermediate between t
264 nitude greater than any previously described membrane channel, with an average diameter of 340 nm and
265 t to subsequently be transported through the membrane channel without the interference of cytosolic b
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