ライフサイエンスコーパス: membrane current

1 BA and picrotoxin induced a large rebound of membrane current.

2 ed with VMD greatly reduces or abolishes the membrane current.

3 e laser-induced fluorescence did not evoke a membrane current.

4 CH, histamine failed to induce an additional membrane current.

5 s were measured by patch-clamp recordings of membrane current.

6 3+/-12 nmol/L after reoxygenation) or evoked membrane current.

7 rrent at voltages where it dominates the net membrane current.

8 the [Ca2+]i transients and [Ca2+]i-activated membrane current.

9 a capsazepine-sensitive outwardly rectifying membrane current.

10 ediated membrane current and Cav1.2-mediated membrane current.

11 inhibited NMDA-evoked, but not AMPA-evoked, membrane currents.

12 temporal heterogeneity of calcium-activated membrane currents.

13 ined the effects of arachidonic acid (AA) on membrane currents.

14 ting membrane potential or endogenous oocyte membrane currents.

15 ed corresponding oscillations in [Ca2+]m and membrane currents.

16 is attributable to the interplay of several membrane currents.

17 directly by gel shift assays and changes in membrane currents.

18 ies and demonstrates the strong influence of membrane currents.

19 ROS production also decreased AVP-stimulated membrane currents.

20 Bulk particles did not modify the plasma membrane currents.

21 cysteine resulted in small or no appreciable membrane currents.

22 and recorded resulting ATP and BzATP-evoked membrane currents.

23 pine (1 microM) reduced the capsaicin-evoked membrane current (6/6) and depolarization (7/7 responder

24 er) increased flavoprotein oxidation but not membrane current; a 10-fold higher concentration recruit

25 Membrane current abnormalities have been described in hu

26 coupling in guinea-pig ureter, by measuring membrane currents, action potentials, intracellular [Ca2

27 of [Ca2+]i (fluo-3-acetoxymethyl ester) and membrane currents/action potentials (patch-clamp) in iso

28 yristate 13-acetate (PMA) increased the mean membrane current activated by a low concentration of cap

29 polarization was caused by a Cl(-)-selective membrane current activated by flow independently of the

30 It was attributed to a regenerative membrane current, active at the resting potential in sen

31 Slowly emerging membrane currents after theta burst stimulation are sens

32 a(2+) content (measured from caffeine-evoked membrane currents) alternated in phase with the alternan

33 Membrane current analysis showed that OH cell firing inc

34 aneous, high time-resolution measurements of membrane current and Ca(2+) fluorescence.

35 g(2+) ([Mg(2+)](o)) inhibited TRPV3-mediated membrane current and calcium influx.

36 rallel reduction in Na/Ca exchanger-mediated membrane current and Cav1.2-mediated membrane current.

37 toKATP channel in simultaneous recordings of membrane current and flavoprotein fluorescence.

38 cordingly, Abeta25-35 peptide also increased membrane current and permeability, as well as intracellu

39 rs with a significantly greater latency than membrane current and potential changes attributable to A

40 directional photomodulation of Purkinje cell membrane current and spike-firing rate.

41 immunostaining and patch clamp recordings of membrane current and voltage, we identified all three SK

42 The interaction between such altered membrane currents and a changed neurohumoral milieu crea

43 increase in large conductance mitochondrial membrane currents and a decrease in bioenergetic efficie

44 Protein levels (Western blot), membrane currents and action potentials (patch clamp), a

45 Membrane currents and action potentials were recorded us

46 though the circadian modulation of intrinsic membrane currents and biochemical signaling have been ex

47 re, we modified the cell EP by changing both membrane currents and calcium handling.

48 Proton-evoked membrane currents and calcium influx through hTRPA1 occu

49 Here, we show that membrane currents and dendritic Ca(2+) signals evoked by

50 endolysosomal Ca(2+) stores activates inward membrane currents and depolarizes the beta cell to the t

51 al potential, suggesting a role in modifying membrane currents and GABA responses in a daily fashion,

52 in kinase C (PKC) resulting in inhibition of membrane currents and increases in intracellular Ca2+ co

53 ceding the phase 0 activation represents the membrane currents and intracellular calcium transients i

54 hemia causes profound changes in both active membrane currents and passive electrical properties.

55 Membrane currents and potential were measured by whole-c

56 bining patch-clamp analysis of spike firing, membrane currents and synaptic inputs with confocal imag

57 eir development, such that their basolateral membrane currents and synaptic machinery retain a pre-he

58 eir development, such that their basolateral membrane currents and synaptic machinery retain a prehea

59 cated in homeostatic regulation of intrinsic membrane currents and synaptic strength, may also regula

60 e of differential expression and function of membrane currents and transporters.

61 The model has seven voltage-dependent membrane currents and uses three Ca2+ sensors acting on

62 Membrane currents and voltage were measured in single my

63 lls showed similar levels of gain control in membrane currents and voltages and under conditions of l

64 n with thapsigargin, inhibited activation of membrane currents and volume recovery.

65 embrane voltage on absorption, fluorescence, membrane current, and membrane capacitance.

66 pipette caused significant filtering of the membrane currents, and that the filter characteristics d

67 roduce a system for simultaneously recording membrane current, applied force, and the resulting inden

68 B1 activation enhanced the heat-activated membrane current approximately 3-fold, and the enhanceme

69 -microm-long dendritic subsegment; dendritic membrane currents are not required for NMDA spike produc

70 sted that PMCA should generate a substantial membrane current as bundles expel Ca2+.

71 ts causes significant alterations in resting membrane current, as measured by whole-cell patch clamp

72 Activation of PKC did not enhance the membrane current at high concentrations of capsaicin, sh

73 nt is likely to have a greater effect on net membrane current at more positive potentials (EK channel

74 in human embryonic kidney cells and measured membrane currents before and after photo-affinity labeli

75 (AChRs) switch on/off to generate transient membrane currents (C<-->O; closed-open 'gating') and ent

76 ion to noxious heat stimuli by enhancing the membrane current carried by the heat- and capsaicin-gate

77 ergy delivered in each touch into excitatory membrane currents carried by mechanoelectrical transduct

78 ultaneous measurements of action potentials, membrane current, cell shortening and changes in intrace

79 and each dominantly inhibited the wild-type membrane current, consistent with the dominant nature of

80 alothane, isoflurane and sevoflurane inhibit membrane currents contributing to the ventricular action

81 Simultaneous recordings of membrane current, DeltaPsim and [Ca2+]i revealed the seq

82 the charge carrier, cell swelling increased membrane current density approximately 30-fold to 16.5 +

83 attenuates glucose- and sulfonylurea-induced membrane currents, depolarization, cytoplasmic Ca(2+) si

84 In addition to membrane current-driven events, a type of dendritic spik

85 s and investigated changes in the underlying membrane currents during M-F coupling.

86 luorescence photometry was used to study the membrane currents during oscillations of intracellular C

87 that the reversal potential of GABA-induced membrane currents (EGABA) was significantly more hyperpo

88 Membrane currents, electrical activity, and exocytosis w

89 ctric field gradients required to porate the membrane, current electroporation devices deliver voltag

90 subunit RNAs were injected into oocytes, and membrane currents elicited by AcCho were recorded under

91 phate receptor inhibitor, did not affect the membrane currents elicited by epidermal growth factor de

92 Therefore, the smaller amplitude of membrane currents elicited by Glu in oocytes injected wi

93 Fluoxetine (Prozac) inhibited the membrane currents elicited by serotonin (5-hydroxytrypta

94 time-dependent activation or inactivation of membrane currents elicited by voltage steps in the range

95 pressed in human embryonic kidney cells, and membrane currents evoked by ATP were recorded.

96 Using patch-clamp recordings, we found that membrane currents evoked by both menthol and innocuous c

97 evoked response, it had no direct effect on membrane currents evoked by exogenous glutamate, kainate

98 en protons and piperine were co-applied, the membrane currents evoked in piperine-sensitive TG neuron

99 By directly recording membrane currents from enlarged lysosomal vacuoles, we d

100 We recorded membrane currents from human embryonic kidney cells expr

101 icroglial cells might sense CSD by recording membrane currents from microglia in acutely isolated cor

102 We add membrane currents from the Luo-Rudy Phase II ventricular

103 The effects of PKC activation on the membrane current gated by heat, anandamide and low pH we

104 s of activation of protein kinase C (PKC) on membrane currents gated by capsaicin, protons, heat and

105 CC2 activity is critical for hyperpolarizing membrane currents generated upon the activation of gamma

106 ICa (measured as nifedipine-sensitive membrane current) had a complex multiphasic time course

107 irect application of ACh caused no change in membrane current, implying absent or otherwise dysfuncti

108 d to characterize the shear stress-sensitive membrane current in atrial myocytes using the whole-cell

109 NpHR3.0) tools to create a slow non-synaptic membrane current in bystander neurons, which matched the

110 from the patch pipette did not activate any membrane current in cells where intracellular calcium co

111 how that NAAG, but not NAA, evokes an inward membrane current in cerebellar white matter oligodendroc

112 enhances the expression of bTREK-1 mRNA and membrane current in cultured AZF cells.

113 We made whole-cell recordings of membrane current in guinea pig ganglion cells in vitro.

114 Flavoprotein fluorescence and membrane current in intact rabbit ventricular myocytes w

115 ar basis, we measured membrane potential and membrane current in mammalian ventricular myocytes by us

116 demonstrate that NMDARs transiently produce membrane current in Purkinje cells and may serve as one

117 ing cystine to cerebellar slices generated a membrane current in Purkinje cells which was abolished b

118 - channels contribute significant whole-cell membrane current in response to changes in intracellular

119 Capsaicin evokes a membrane current in trigeminal ganglion neurons that is

120 used to regulate the maximal conductances of membrane currents in an activity-dependent manner.

121 oxygen species, activated Ca(2+) influx and membrane currents in an oxidant-sensitive subpopulation

122 type Ca2+ channels, reduced constriction and membrane currents in cerebral arteries from SAH animals,

123 addition, we characterized voltage-dependent membrane currents in each type of primate retinal cell w

124 We recorded membrane currents in HEK293 cells transfected to express

125 We measured cellular fluorescence and membrane currents in individual human embryonic kidney c

126 ated patch clamp technique was used to study membrane currents in isolated rabbit corpus cavernosum s

127 he patch-clamp technique was used to measure membrane currents in isolated smooth muscle cells disper

128 re caused by activation of Ca(2+) influx and membrane currents in mustard oil-sensitive sensory neuro

129 l patch-clamp techniques were used to record membrane currents in neuroblastoma cells stably transfec

130 e-cell patch-clamp recording to measure cell-membrane currents in primary cultures of podocytes from

131 ions of MFQ attenuated increased macroscopic membrane currents in primary mouse keratinocytes express

132 een assessed one cell at a time by recording membrane currents in response to application of focal pr

133 Recording of membrane currents in response to ATP (whole cell and exc

134 We measured membrane currents in response to ATP and BzATP at wild-t

135 of cannabinoid (CB) receptor stimulation on membrane currents in single cells from the Syrian hamste

136 on were studied with whole-cell recording of membrane currents in single smooth muscle cells from the

137 r, failed to have any additional effect upon membrane currents in the presence of CN(-) or rotenone o

138 Membrane currents in these motor neurons oscillated in p

139 urrents, as well as GABA application-induced membrane currents, in a dose-dependent manner.

140 The reversal potential of the membrane current induced by PKC activators was approxima

141 Membrane currents induced by citrate were bigger than th

142 ained in the absence of NCX, we investigated membrane currents, intracellular Ca2+, and action potent

143 chniques were combined to examine changes in membrane currents, intracellular calcium ([Ca2+]i) and m

144 f a complex V-associated inner mitochondrial membrane current is metabolically important and may repr

145 haracterized through an analysis of charging membrane currents measured with tight-seal electrodes in

146 at the level of channel mRNA expression and membrane currents (measured in voltage-clamp experiments

147 Changes in protein levels and membrane currents mirrored changes in transcript levels,

148 ithin the ventral posterior medial thalamus, membrane currents modulated by norepinephrine have been

149 ll nonselective cation current so that total membrane current near -70 mV shifted to become barely ne

150 engaged or disengaged by small shifts in net membrane current near -70 mV, as by muscarinic stimulati

151 (mGluR1 and 5) agonist reduced NMDA-mediated membrane currents, NMDA-induced cell death and up-regula

152 Low-frequency light-sensitive membrane current noise in isolated rod photoreceptors of

153 tch-clamp methods were invented, analysis of membrane current noise provided the first solid, if indi

154 ated with increases of input conductance and membrane current noise, and reversed close to 0 mV, indi

155 roduced an inward current and an increase in membrane current noise, which were accompanied by a cond

156 lectrophysiology, but efforts to measure the membrane current of intact GUVs have been unsuccessful.

157 brief flashes of light were recorded in the membrane current of isolated rods from larval tiger sala

158 The effect of extracellular K+ on membrane currents of bull frog (Rana catesbeiana) taste

159 Thus, membrane currents of oocytes of Xenopus laevis expressin

160 al impact of anaesthetic-induced blockade of membrane currents on APD and effective refractory period

161 ne simultaneously the effects of alpha-LT on membrane current or voltage, cytosolic Ca, and membrane

162 CaTs were monitored simultaneously with membrane currents or APs recorded with the patch clamp t

163 n be driven by the kinetics of voltage-gated membrane currents or by instabilities in intracellular c

164 0 microM) nor L-AP4 (0.001-50 microM) caused membrane currents or changes in the current-voltage rela

165 DHPG also elicited slow membrane current oscillations and spikelets in ET cells

166 kers, ET cell pairs exhibit synchronous slow membrane current oscillations associated with rhythmic s

167 induced significant increases in whole-cell membrane currents (P<0.01) in the presence of the coagon

168 buted to the greater duration of the outward membrane current phase, resulting in a greater outward c

169 In addition, the prominent membrane current rebound when co-application of GABA and

170 f genistein, a tyrosine kinase inhibitor, on membrane currents recorded from isolated guinea pig vent

171 l activity was discernible in the whole cell membrane current recordings.

172 [Ca2+]i and membrane current recovered only after mitochondrial repo

173 rent following hypotonic shock, by recording membrane current responses and cell volume changes in vo

174 e benzodiazepinones inhibited AMPA-activated membrane current responses in a manner consistent with n

175 ated the action of propofol on GABA-elicited membrane current responses of retinal bipolar cells, whi

176 hat the amiloride-sensitive component of the membrane current reversed at a potential close to the Na

177 igh [K+]o alone did not significantly affect membrane current, Rm, or Vm in AV nodal myocytes.

178 Aspartate was shown to induce a large membrane current sensitive to N-methyl-D-aspartate (NMDA

179 Recording of whole-cell membrane currents showed that four receptors operated as

180 MSCs were found to exhibit voltage-dependent membrane currents similar to the neuronally guided BMSCs

181 le through its influence on Ca(2+)-sensitive membrane currents such as I(Ca), I(NaCa), and I(ns(Ca)).

182 uced a cellular calcium influx and an inward membrane current that was entirely prevented by d-tubocu

183 xplained by a marked inward shift in the net membrane current that was observed in these experiments.

184 nicamycin produced gel shifts and changes in membrane currents that correlated exactly.

185 been constructed that incorporates the major membrane currents that have been isolated in recent expe

186 e primarily due to 5HT-induced modulation of membrane currents that indirectly affect junctional coup

187 GABA elicited desensitizing membrane currents that recovered after a few minutes' wa

188 nated the high affinity site and resulted in membrane currents that were only partially inhibited at

189 rge inward (toward the cytosolic side of the membrane) current that is activated in a time-dependent

190 hough ischaemia evokes a glutamate-triggered membrane current, this is generated by a rise of extrace

191 uently recovered accurate estimates of patch membrane current through deconvolution.

192 Membrane current through voltage-sensitive calcium ion c

193 deled as spatially and temporally nonuniform membrane currents through mechanosensitive channels, the

194 tes results in light-dependent activation of membrane currents through the Galpha(q)/Galpha(11) G pro

195 Exposure to NH4Cl increased the membrane currents to a similar extent in uninjected oocy

196 ing recorded from, and to attribute measured membrane currents to expressed ion channels or receptors

197 sets the maximal conductances for its active membrane currents to values that produce a predefined ta

198 irect activator of TRPC6 both augmented cell-membrane currents; TRPC6 deficiency abrogated these incr

199 Membrane currents under voltage clamp were determined in

200 Different blends of membrane currents underlie distinct functions of neurons

201 ll caused a slow TBOA-sensitive decay in the membrane current upon prolonged application, which provi

202 rat dorsal root ganglia neurons, we measured membrane currents, using the patch-clamp whole-cell tech

203 A membrane current was detected with the pharmacology, vol

204 s and RyRs to SK and BK channels, whole cell membrane current was measured in isolated myocytes bathe

205 In control, total membrane current was net outward (hyperpolarizing) near

206 With K+ currents blocked, total membrane current was outward during the late plateau of

207 Membrane current was recorded from intact, isolated rods

208 When membrane current was recorded simultaneously, the calciu

209 d with double-barrelled micro-electrodes and membrane current was recorded under voltage clamp in the

210 The voltage dependence of membrane current was similar in all neurons examined, su

211 Using a Hodgkin-Huxley-style model of membrane currents, we show that differences in the influ

212 The DHPG effects on bursting and membrane current were attenuated by flufenamic acid and

213 [Ca(2+)](i) and membrane current were measured in human submandibular gl

214 The EC50 values for SP and [beta-Ala8]NKA membrane currents were 78 and 33 nM, respectively.

215 Citrate-induced membrane currents were also sensitive to pH, consistent

216 Membrane currents were analyzed using whole-cell, patch-

217 sms of action for NGF and ceramide, isolated membrane currents were examined.

218 Membrane currents were measured using the perforated pat

219 Membrane currents were measured with the use of the whol

220 were assessed using hydroethidium (HEt); and membrane currents were measured with the whole-cell conf

221 Membrane currents were recorded using a two-electrode vo

222 and indo-1 while action potentials (APs) or membrane currents were recorded using patch-type microel

223 Membrane currents were recorded using whole cell patch c

224 Membrane currents were recorded while manipulating the e

225 ld, high-speed, digital imaging system while membrane currents were simultaneously recorded using who

226 Membrane currents were strongly and reversibly inhibited

227 Membrane currents were studied in single human blood eos

228 Membrane currents were subsequently recorded with whole-

229 is detected by measuring the change in trans-membrane current when the analyte is added to the nanotu

230 ostone (an EP3 agonist) had little effect on membrane current, whereas butaprost methyl ester (an EP2

231 d propagation, suggesting that modulation of membrane currents which affect propagation in the apical

232 This protection also alters a surface membrane current, which may be important in myocardial p

233 The reuptake process generates membrane currents, which can be activated by synapticall

234 tivation of Cl--dependent outward-rectifying membrane currents with an anion permeability sequence of

235 Whole cell membrane currents with distinctive inward and outward re

236 orm functional homomeric channels, displayed membrane currents with properties distinct from those ex

237 Correlation of membrane currents with radiolabeled myo-inositol flux re