ライフサイエンスコーパス: membrane fluidity

1 ed for fusion, likely through an increase in membrane fluidity.

2 ent with known effects of LPS composition on membrane fluidity.

3 amic properties, indicating a high degree of membrane fluidity.

4 bilayer samples and make measurements of the membrane fluidity.

5 al to the formation of neuronal synapses and membrane fluidity.

6 brane accounts for the effects of calcium on membrane fluidity.

7 phospholipids and contribute to maintaining membrane fluidity.

8 erve to mitigate the effect of aS binding on membrane fluidity.

9 ther than producing the proposed increase in membrane fluidity.

10 itive to the lipid composition as well as to membrane fluidity.

11 nverting enzyme, TACE, possibly by affecting membrane fluidity.

12 e phospholipid vesicles and suppressed their membrane fluidity.

13 id unsaturation, and that sHsps can regulate membrane fluidity.

14 saturated fatty acids is thought to modulate membrane fluidity.

15 e receptor complex, or increases in neuronal membrane fluidity.

16 the lipid bilayer, leading to a reduction in membrane fluidity.

17 bind bis-ANS and had little to no effect on membrane fluidity.

18 hydrophobic sites and induces a decrease in membrane fluidity.

19 ly correlated with the extent of decrease in membrane fluidity.

20 with phospholipid vesicles and suppress the membrane fluidity.

21 -arginine or tetrahydrobiopterin, or reduced membrane fluidity.

22 nterleukin 2 and -1beta production, and PBMC membrane fluidity.

23 C2-Dihydroceramide did not alter membrane fluidity.

24 ed phospholipids, which ultimately reduce ER membrane fluidity.

25 less potent than native BSA in altering the membrane fluidity.

26 ith a pulse of intense light as a measure of membrane fluidity.

27 reducing LPS levels, which in turn may alter membrane fluidity.

28 g that both can be used by cells to maintain membrane fluidity.

29 ng, affecting cellular lipid composition and membrane fluidity.

30 sterols and phospholipids to control proper membrane fluidity.

31 nt of fluid lipid domains, affecting overall membrane fluidity.

32 ions in fatty acid composition and increased membrane fluidity.

33 LDL), potentially by increasing the cellular membrane fluidity.

34 y adjusting levels of lipid desaturation and membrane fluidity.

35 interaction with phospholipids is driven by membrane fluidity.

36 nse lipids, in addition to the modulation of membrane fluidity.

37 its related actin structures and the plasma membrane fluidity.

38 by a benzyl alcohol-mediated enhancement of membrane fluidity.

39 rsus saturated fatty acyl chains, determines membrane fluidity.

40 The net effect is to reduce membrane fluidity.

41 tributes to a sigma(W)-dependent decrease in membrane fluidity.

42 A beta aggregates affected membrane fluidity above, but not below, the lipid phase-

43 te that changes in cell membrane tension and membrane fluidity affect conformational dynamics of GPCR

44 showed that this cls mutation helps maintain membrane fluidity after freezing and thawing and improve

45 on (P=0.185), but IGL-1 prevented changes in membrane fluidity after reperfusion when compared with U

46 Increased membrane fluidity also supports hIBPLA(2) activity, sugg

47 ol/L) caused the opposite effect, increasing membrane fluidity and antagonizing the effect of BSA.

48 Cholesterol influences membrane fluidity and assembles lipid-rich microdomains

49 Arl3, the location of the N-terminal helix, membrane fluidity and binding, and the release of lipid

50 PP species, especially fresh hIAPP, enhanced membrane fluidity and caused losses in cell viability.

51 The correlation between changes in membrane fluidity and cell viability and their lack of c

52 likely is the direct result of changes in ER membrane fluidity and composition.

53 acterial cell membranes because they control membrane fluidity and diminish passive diffusion of ions

54 Cooling and warming alter membrane fluidity and elicit intracellular free-calcium

55 nes; (b) membrane insertion is controlled by membrane fluidity and facilitates activation of IB and I

56 anchored to the SSLBMs exhibited significant membrane fluidity and have been directed into dimer asse

57 rane insertion of hIBPLA(2) is controlled by membrane fluidity and is necessary for the full activity

58 ve stress in the pancreatic graft monitoring membrane fluidity and lipid peroxidation.

59 ding and insertion of 5-LO through increased membrane fluidity and may thereby modulate the activity

60 ug-resistant cells have suggested changes in membrane fluidity and membrane potential associated with

61 ells that express P-gp showed an increase in membrane fluidity and membrane potential.

62 c phospholipase A2alpha (cPLA2alpha) affects membrane fluidity and permeability by catalyzing the hyd

63 eled cells contains useful information about membrane fluidity and polarity.

64 Consistent with this increased membrane fluidity and reduced capture, ethanol reduced r

65 AA1 binding also inhibits membrane fluidity and reduces solvent accessibility arou

66 ctured loop provides selectivity for sensing membrane fluidity and targeting to defined membrane zone

67 Instead, increased platelet membrane fluidity and the epsilon4 allele appear to make

68 In accord, membrane fluidity and the levels of certain PUFAs were d

69 s a key factor determining lipid packing and membrane fluidity, and it must be tightly controlled to

70 hat cells depleted of cholesterol had higher membrane fluidity, and more uniform distribution of CD44

71 was correlated with decreased levels of UFA, membrane fluidity, and plasticity.

72 nce to the cationic defensin hNP-1, enhanced membrane fluidity, and substantially greater adhesion to

73 l as on the repulsive forces associated with membrane fluidity, and that small changes in any of thes

74 Age, increased platelet membrane fluidity, and the APOE epsilon4 allele made sig

75 cis-unsaturated fatty acids decrease Saureus membrane fluidity, and these altered membrane dynamics a

76 tinct membrane domains which differ in local membrane fluidity, and which severely disrupts membrane

77 t prospective evidence of increased platelet membrane fluidity as a biological risk factor for Alzhei

78 Collectively, our findings reveal increased membrane fluidity as a necessary cellular feature of met

79 his study was to evaluate increased platelet membrane fluidity as a putative risk factor for Alzheime

80 his study was to evaluate increased platelet membrane fluidity as a putative risk factor for Alzheime

81 , there was no correlation of the rates with membrane fluidity as measured by fluorescence polarizati

82 inding of galanin to GalR2 is independent of membrane fluidity as, like cholesterol, cholesterol anal

83 ith bipolar disorder would result in greater membrane fluidity, as detected by reductions in T(2) val

84 gamma-globulin and myoglobin, decreased the membrane fluidity (assessed as changes in the steady-sta

85 ing myelin formation, cholesterol influences membrane fluidity, associates with myelin proteins such

86 esirability of maintaining the optimal outer membrane fluidity at 12 degrees C.

87 ures, but they begin to possess appreciable "membrane fluidity" at temperatures close to the minimum

88 y due to arachidonic acid-induced changes in membrane fluidity, because 11,14,17-eicosatrienoic acid

89 onstrate the importance of the difference in membrane fluidity between the gel phase DMPC and the liq

90 t cWFW instead triggers a rapid reduction of membrane fluidity both in live Bacillus subtilis cells a

91 n at different temperatures and analyzed the membrane fluidity by fluorescence anisotropy measurement

92 smotic challenge shorten the cell and reduce membrane fluidity by half.

93 Tuning the degree of membrane fluidity by tailoring the amount of plasticizin

94 on, but disentangling lipid composition from membrane fluidity can be obtained if time resolved spect

95 ell as the perturbation of RhoA activity and membrane fluidity, can block this HSS-induced FAK polari

96 ution after photobleaching (FRAP) to examine membrane fluidity changes.

97 This review focuses on the architecture of a membrane fluidity communication network; how thermal inf

98 tropy revealed that DCA causes a decrease in membrane fluidity consistent with the increase in membra

99 Decreases in membrane fluidity could hamper functioning of cell surfa

100 omitant measurements of mechanics and plasma membrane fluidity demonstrate that changes in actin patt

101 binding sterol (dehydroergosterol), altering membrane fluidity (diphenylhexatriene) or membrane perme

102 terol from the membrane, leading to enhanced membrane fluidity, disruption of rafts, and impaired ant

103 tion decreases cholesterol levels, increases membrane fluidity, disrupts lipid rafts, and redistribut

104 ng that these compounds likely help maintain membrane fluidity during dehydration.

105 nt of the membranes with other modulators of membrane fluidity, e.g. ethanol, did not affect galanin

106 Both of these mechanisms likely regulate membrane fluidity, facilitating the maintenance of effic

107 of cyclopropane fatty acids, (iii) increased membrane fluidity following the initial response of incr

108 Though the importance of membrane fluidity for cellular function has been well es

109 luorescence decay can distinguish changes in membrane fluidity from changes in cholesterol content.

110 Our study suggests that regulation of membrane fluidity has been among the important adaptatio

111 tly, Abeta aggregated at pH 6 or 7 decreased membrane fluidity in a time- and dose-dependent manner.

112 orrelation between transfection and enhanced membrane fluidity in both the lipoplex and cellular memb

113 of varying chemical structures can alter the membrane fluidity in either direction and correspondingl

114 adders with pigment stones, reflecting lower membrane fluidity in gallbladders with cholesterol stone

115 serotonin receptor action by increasing cell membrane fluidity in postsynaptic neurons.

116 thermosensor protein involved in maintaining membrane fluidity in response to changes in environmenta

117 mbrane fraction was accompanied by increased membrane fluidity in the alphaS overexpressing neurons.

118 flected in corresponding differences in cell membrane fluidity in the strain pairs, with tPMP-1(r) st

119 P confirmed the r results and indicated that membrane fluidity increased while its structure became l

120 responses to calcium influx were enhanced as membrane fluidity increased.

121 hotobleaching revealed an increase in plasma membrane fluidity induced by cryptogein, but not by flag

122 Here we show that membrane fluidity is an important determinant of membran

123 We conclude that membrane fluidity is an important physicochemical parame

124 In many organisms, regulation of membrane fluidity is crucial for acclimating to variatio

125 In most eukaryotic cells, membrane fluidity is known to be regulated by fatty acid

126 In all cases, the membrane fluidity is maintained, indicating that both ce

127 ese results indicate that increased platelet membrane fluidity is not produced by the APOE epsilon4 a

128 Membrane fluidity is one of the important parameters inv

129 Adequate membrane fluidity is required for a variety of key cellu

130 n, a voltage-gated peptide channel for which membrane fluidity is required for activity, was reconsti

131 incompatible with ion channel function when membrane fluidity is required.

132 Though the existence of membrane fluidity is well established, the nature of thi

133 ncommon capability of CerC16 to modulate the membrane fluidity, its curvature propensity, and the mem

134 esterol (Bdp-Chol) derivative to investigate membrane fluidity, lipid order, and partitioning in vari

135 t important, both age and increased platelet membrane fluidity made significant independent contribut

136 The ability of SM to decrease membrane fluidity may explain, at least in part, its cyt

137 Cholesterol, which impedes membrane fluidity, may lower APPsol production by impedi

138 structural change is accompanied by reduced membrane fluidity (measured by infrared ellipsometry).

139 pressure, and nonperturbing in that neither membrane fluidity nor order were affected, as monitored

140 g lipid-lipid interactions, lipid order, and membrane fluidity of biologically relevant L(o) domains.

141 < 0.005) less than those of cholangiocytes; membrane fluidity of hepatocytes estimated by measuring

142 nt of the cells with 3 micromol/L RA reduced membrane fluidity of the cells under both high- and low-

143 The effect of Abeta aggregation state on the membrane fluidity of unilamellar liposomes was assessed

144 ut also, as we previously reported, decrease membrane fluidity on mouse polymorphonuclear leukocytes

145 activation does not reflect any nonspecific membrane fluidity or detergent effects, shows a high deg

146 pression of P-gp per se has little effect on membrane fluidity or membrane potential, and it does not

147 to lipid composition and suggest that proper membrane fluidity or plasticity is essential for an earl

148 tagonist flumazenil, which has no effects on membrane fluidity or voltage-dependent calcium channel f

149 onic lipids, cholesterol, sphingomyelin, and membrane fluidity play critical roles in these processes

150 anionic lipids and bilayer curvature, while membrane fluidity plays a very minor role.

151 Membrane fluidity plays an important role in cell functi

152 It also showed no relevant effects on membrane fluidity, polarity or partitioning of the spin

153 ow levels of benzyl alcohol, which increases membrane fluidity, prevented Nup mislocalization and res

154 to the levels of untreated cells, restoring membrane fluidity, preventing the morphological changes,

155 ral effects, including increases in cellular membrane fluidity, promotion of neurite extension and in

156 ped molecular strategies to sense changes in membrane fluidity, provoked by a decrease in environment

157 These dynamic changes in membrane fluidity represent the modulation of membrane t

158 sterol/phospholipid mole ratio and decreased membrane fluidity resulting in impaired muscle contracti

159 h the putative antimetastasis agents reduced membrane fluidity, resulting in decreased cell motility,

160 tent and cholesterol/phospholipid ratio, and membrane fluidity returned to normal levels.

161 ids are essential to brain functions such as membrane fluidity, signal transduction, and cell surviva

162 l properties such as acyl chain composition, membrane fluidity, surface curvature, microdomains, head

163 sion coefficient, lipid order parameter, and membrane fluidity that are sensitive to phase domains.

164 These changes resulted in increased plasma membrane fluidity that renders them susceptible to react

165 etter the effect that lipid chemistry has on membrane fluidity the inclusion of three different lipid

166 Finally, because SM decreases membrane fluidity, the impact of a fluidizing agent (A(2

167 n which heme and ergosterol depletion alters membrane fluidity, thereby activating Hog1 for hypoxic i

168 ovides a mechanism to conditionally decrease membrane fluidity through the opposed regulation of FabH

169 may have been achieved by altering the outer membrane fluidity, thus making it more amenable for the

170 ussis adapted its fatty acid composition and membrane fluidity to a considerably lesser extent when c

171 l-CoA desaturase (SCD) is a key regulator of membrane fluidity, turns over rapidly, and represents a

172 yme A desaturase (SCD) is a key regulator of membrane fluidity, turns over rapidly, and represents a

173 oad categories involving changes to the cell membrane fluidity, uptake and synthesis of compounds con

174 ependent effects of trans-resveratrol on the membrane fluidity using planar lipid bilayer and liposom

175 ial using the fluorescent probe oxonol or in membrane "fluidity" using fluorescent anisotropy probe o

176 to regulation of lipid desaturase levels and membrane fluidity via an unprecedented mode of fatty aci

177 Increased platelet membrane fluidity was associated with incident Alzheimer

178 Membrane fluidity was determined by using fluorescence p

179 Using this approach, we observed that membrane fluidity was higher when the cells were incubat

180 ct of these substances on [3H]AA release and membrane fluidity was studied in vascular myocytes and e

181 whose activities are a major determinant of membrane fluidity, we asked whether membrane-associated

182 Because tumor cells exhibit altered membrane fluidity, we suggest this might influence pHLIP

183 ber of antioxidant genes and genes affecting membrane fluidity were up-regulated in both irradiated s

184 and physical stability and for influence on membrane fluidity, when quercetin and fish oil were enca

185 stabilizes positive curvature and decreases membrane fluidity, which inhibits virus-cell membrane fu

186 Strikingly, increasing membrane fluidity with benzyl alcohol treatment prevente