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1 ssed alone, Loop1 remained intracellular and membrane-bound.
2 hich only the higher-affinity module remains membrane-bound.
3 t-studied bacterial chemoreceptor arrays are membrane-bound.
4 to our knowledge) new procedures to assemble membrane-bound 1:1 SNARE acceptor complexes that produce
5 ganelle acidification in all eukaryotes, and membrane-bound a-subunit isoforms of the V-ATPase are im
6 using DHLMP2A mice, which lack secreted and membrane-bound Ab, yet harbor marginal zone and follicul
7 components of the respiratory burst oxidase, membrane-bound adhesion molecules, and receptors that fa
8 he risk factor molecules stabilizes a common membrane-bound alpha-helical intermediate that, in turn,
13 chemical inhibition of Porcupine reduced the membrane-bound and secreted fractions of Wnt3 and eventu
16 ns, it is now clear that the presentation of membrane-bound antigen plays a crucial role in B cell ac
17 assemblies provides an opportunity to image membrane-bound AQP4 antibodies (AQP4-IgG) and evaluate c
18 LA2) activity with a preferential release of membrane-bound arachidonic acid, stimulating the lipoxyg
20 s and in different biochemical states (i.e., membrane bound as in brain microsomes from wild-type mic
22 in pfmdr1, which encodes a digestive vacuole membrane-bound ATP-binding cassette transporter known to
23 positive pathogen Staphylococcus aureus, the membrane-bound ATP-dependent metalloprotease FtsH plays
25 separate localization of both enzymes, as a membrane-bound beta-glucosidase could specifically diges
26 via activation of the ubiquitously expressed membrane-bound beta-receptor glycoprotein 130 (gp130).
30 anding of their biological functions, intact membrane-bound bitopic protein-protein complexes pose tr
31 tors and their precursors against a panel of membrane-bound CA isoforms, including tumor-overexpresse
38 hese results suggest that local structure of membrane-bound chiral filaments is generically sensitive
40 nd in some cases appears to divide, within a membrane-bound compartment for the entire 6-day time cou
41 racellular pathogens that replicate within a membrane-bound compartment inside infected host cells kn
42 xit via extrusion generates a distinct, host-membrane-bound compartment of Chlamydia separate from th
43 ocytes contain a Balbiani body, a large, non-membrane-bound compartment packed with RNA, mitochondria
45 s move proteins and lipids from one internal membrane-bound compartment to another within the secreto
47 strate that FABP4 secretion is mediated by a membrane-bounded compartment, independent of the convent
48 at promotes maintenance of Mtb within intact membrane-bound compartments for efficient elimination.
50 required to build, maintain, and define many membrane-bound compartments is encoded by several paralo
52 ses represent identity markers for different membrane-bound compartments, and each Rab organizes a co
53 nts that mediate degradation of pathogens in membrane-bound compartments, in a process termed xenopha
54 In living cells, reactions take place in membrane-bound compartments, often in response to change
58 However, the stability of the circa 70 kDa membrane-bound complex in model membranes renders high-r
59 ement system, consisting of soluble and cell membrane-bound components of the innate immune system, h
60 l granules contain microbicidal factors, the membrane-bound components of the respiratory burst oxida
62 hat the existing crystal structure be in the membrane-bound conformation for effective x-ray reflecti
69 the connection between spine morphology and membrane-bound diffusion through a combination of photoc
70 by co-immunoprecipitation experiments, where membrane-bound dimers were successfully pulled down from
72 Some protein components of intracellular non-membrane-bound entities, such as RNA granules, are known
74 a stabilized, cleaved trimer (SOSIP) or by a membrane-bound Env trimer with a truncated cytoplasmic t
75 tive trimeric form of an efficiently cleaved membrane-bound Env, 4-2.J41, may be beneficial for immun
79 egrin and metalloproteinase 17 (ADAM17) is a membrane-bound enzyme that mediates shedding of many mem
81 iquinone oxidoreductase), one of the largest membrane-bound enzymes in mammalian cells, powers ATP sy
82 iquinone oxidoreductase), one of the largest membrane-bound enzymes in the cell, powers ATP synthesis
84 ranslational evidence that the ectodomain of membrane-bound ephrin-B2 is shed from fibroblasts into t
85 dual cytoplasmic/membrane localization, and membrane-bound EsaE interacts with the T7SS secretion AT
87 rect interaction by association of NM2s with membrane-bound F-actin or peripheral membrane proteins.
88 r by coupling the reoxidation of ETFred to a membrane-bound FeS oxidoreductase functioning as an ETF:
90 ed between a translational start codon and a membrane-bound fluorescent protein lacking its start cod
91 gating the conformational dynamics of intact membrane-bound FoF1 during rotational catalysis has prov
92 affinity for narrow mitochondria, acts as a membrane-bound force sensor to recruit the fission machi
93 But in agreement with previous work, the membrane bound form of Cripto-1 potentiated signaling, r
95 t-transcriptional expression switch from the membrane-bound form of the immunoglobulin heavy chain to
96 hat is natively unfolded and monomeric and a membrane-bound form that is composed of an alpha-helical
100 structural and topological investigations of membrane-bound full-length bitopic protein complexes und
102 ion of wound healing by interaction with the membrane bound GC receptor, followed by stimulation of b
103 nchoring to the membrane, induces release of membrane-bound glycolytic enzymes and in turn switches g
104 ing to the membrane, enhances the release of membrane-bound glycolytic enzymes to the cytosol, induce
107 rocytes were prelabeled by the expression of membrane-bound Green fluorescent protein, we found that
108 with the hypotheses that Nogo receptors are membrane-bound growth cone repellent factors required fo
109 INM targeting, we establish that Atlastins, membrane-bound GTPases of the ER, sustain the efficient
113 quence, RBCs that display a cell surface Ag, membrane-bound hen egg lysozyme, strongly activate Ag-sp
114 y, we investigated the involvement of plasma membrane-bound heparan and chondroitin sulfate proteogly
115 the lumen of the endoplasmic reticulum, is a membrane-bound hetero-pentameric complex consisting of G
116 sfer of electrons to oxygen is mediated by a membrane-bound heterodimer, comprising gp91phox and p22p
117 of methyl group oxidation to CO2 as well as membrane-bound heterodisulfide reductase and cytochromes
118 ng BAFF or APRIL multitrimers, IL-12p70, and membrane-bound HIV-1 Env gp140 induced tier 1 and tier 2
120 ed for MHC class I-related chain A and B and membrane-bound IL-15 in IFN-DC-mediated NK cell activati
121 distinct modes: classical signaling via its membrane-bound IL-6 receptor (IL-6R), and trans-signalin
125 accharomyces cerevisiae, inactivation of the membrane-bound IMQC protease Oma1 interferes with oxidat
126 en Anaplasma phagocytophilum develops within membrane-bound inclusions in the host cell cytoplasm.
128 is an essential adhesion protein that links membrane-bound integrin and cadherin receptors through t
130 initiated a phase 1 dose-escalation study of membrane-bound interleukin 21 (mbIL21) expanded donor NK
131 mechanism points to a critical role for the membrane-bound intermediate in disease pathogenesis, mak
132 s occur in specialized organelles, requiring membrane-bound intracellular transporters to partition M
135 the fixed and well-defined structure of the membrane-bound K segments suggests that dehydrins have t
138 ase (pvLAAD) belongs to a class of bacterial membrane-bound LAADs mainly express in genus Proteus, Pr
140 lternative inflammatory mechanism, including membrane-bound lymphotoxin-beta receptor (LTbetaR) and C
141 nisms capable of biomineralizing nano-sized, membrane-bound, magnetic iron-rich mineral particles cal
142 east partly due to decreased delivery of the membrane-bound matrix metalloproteinase MMP-14 to the pl
143 recognize senescent cells by the presence of membrane-bound MDA-vimentin, presumably as part of a sen
145 ular silicone oil droplets, singly dispersed membrane-bound melanin granules, glial tissue (1 case),
146 h a nonheme diiron catalytic site; pMMO is a membrane-bound metalloenzyme with a unique tricopper clu
147 on fluorescence microscopy, we show that the membrane-bound metalloproteinase MT1-MMP is enriched not
148 with the ability to image cultured cells and membrane-bound microbeads in twelve independently-focusi
149 d as secreted/soluble antibodies (sIg) or as membrane-bound (mIg) B cell receptors (BCRs) through alt
150 iruses replicate their RNA genomes in novel, membrane-bounded mini-organelles, but the organization o
151 pe 1 matrix metalloproteinase (MT1-MMP) is a membrane-bound MMP that is highly expressed in cells wit
153 phyllobilin hydroxylation is catalyzed by a membrane-bound, molecular oxygen-dependent, and ferredox
155 -bound enzyme that mediates shedding of many membrane-bound molecules, thereby regulating multiple ce
158 acromolecules (e.g., tubulin and actin) as a membrane-bound multimeric complex that favors p35 bindin
160 measured the diffusion coefficient of single membrane-bound Myo1c molecules by force-relaxation exper
161 experiments, and the ability of ensembles of membrane-bound Myo1c molecules to develop and sustain fo
162 " agent, thrombalexin (TLN), combines a cell-membrane-bound (myristoyl tail) anti-thrombin (hirudin-l
163 ze differential expression pattern of tomato membrane bound NAC transcription factors (SlNACMTFs) dur
164 ze differential expression pattern of tomato membrane bound NAC transcription factors (SlNACMTFs) dur
165 teria that synthesise magnetosomes, magnetic membrane-bound nanoparticles that have a variety of diag
166 human CD34(+) cells contains proangiogenic, membrane-bound nanovesicles called exosomes (CD34Exo).
169 a phenomenon that gives rise to diverse non-membrane-bound nuclear, cytoplasmic and extracellular co
170 8 C>T variant in the locus that contains the membrane bound O-acyltransferase domain-containing 7 gen
171 to a small, plant-specific subfamily of the membrane bound O-acyltransferases (MBOAT) that acylate d
175 hematopoietic lineages by targeting Porcn, a membrane-bound O-acyltransferase that is indispensable f
177 t the palmitoylation of Wnt3 by Porcupine, a membrane-bound O-acyltransferase, plays a significant ro
178 estigating the interactions of the polytopic membrane-bound oligosaccharyl transferases (OTases) with
181 dies indicated that HA cleavage is driven by membrane-bound or extracellular serine proteases in the
183 % of global CO2 fixation occurs inside a non-membrane-bound organelle called the pyrenoid, which is f
184 and triacylglycerol (TAG) are stored in the membrane-bound organelle lipid droplet (LD) in essential
185 nd five-way interactions among six different membrane-bound organelles (endoplasmic reticulum, Golgi,
186 ization of the eukaryotic cell into discrete membrane-bound organelles allows for the separation of i
187 components to and from the cell surface and membrane-bound organelles and for changes in cell shape,
188 ghly compartmentalized space containing both membrane-bound organelles and the recently identified no
191 processes can be encapsulated within either membrane-bound organelles or proteinaceous compartments
193 actors function to organize, shape, and move membrane-bound organelles, yet they remain poorly define
199 min-specific T cells in rat insulin promoter-membrane-bound ovalbumin transgenic mice after sham or I
200 is able to deliver electrons to a variety of membrane-bound oxidative partners, including the drug-me
201 Dynamic interactions between full-length membrane-bound P450 and its redox partner cytochrome b5
203 of malaria, Plasmodium, replicates inside a membrane-bound parasitophorous vacuole (PV), which shiel
205 her withdraw from or extend toward the inner membrane-bound PBP1A through peptidoglycan gaps and henc
206 applied to characterize model membranes and membrane-bound peptides and proteins, giving unique info
207 One can also obtain direct information for membrane-bound peptides or proteins by measuring RDCs us
209 creen in zebrafish and identified Cavin-2, a membrane-bound phosphatidylserine-binding protein and cr
211 , two possibly involved in biogenesis of the membrane-bound photosynthetic apparatus and one for phos
213 ch greatly speeds the formation of a stable, membrane-bound PI3Kalpha complex, modestly slows its off
214 inhibits the specific kinase activity of the membrane-bound PI3Kalpha molecule, but this minor enzyme
215 reveal that the pore assembly proceeds via a membrane-bound prepore intermediate state, typically con
218 ome c oxidase from Thermus thermophilus is a membrane-bound protein complex that couples electron tra
219 e prokaryotes by shuttling electrons between membrane-bound protein complexes acting as electron acce
222 that activation of the p120 form of Nrf1, a membrane-bound protein in the endoplasmic reticulum (ER)
223 to understand how bryostatin interacts with membrane-bound protein kinase C, offering insights for t
224 , and those aspects of Gag assembly into the membrane-bound protein lattice that are determined by MA
225 id bilayers is extended by the presence of a membrane-bound protein, up to around 10 A above that pro
226 omains act in concert to condense Gag into a membrane-bounded protein lattice that recruits genomic R
229 e approach to solubilizing and administering membrane-bound proteins for future vaccine development.
231 rane suppresses synthesis of the secreted or membrane-bound proteins including a number of oncogenes,
234 As Stresses are perceived and transmitted by membrane-bound proteins, functional characterization of
235 racting proteins of which one-half comprised membrane-bound proteins, localized to the plasma membran
238 polysaccharides components of extracellular membrane-bound proteoglycans, namely aggregation factors
241 the strategy to measure drug engagement of a membrane bound receptor (CD40) that is critical to immun
242 receptors (GPCRs) are the largest family of membrane-bound receptors and constitute about 50% of all
243 ults from sensing environmental cues through membrane-bound receptors and related intracellular signa
245 n chlamydial pathogens form an intracellular membrane-bound replicative niche termed the inclusion, w
246 ing this approach, we discovered that plasma membrane-bound respiratory syncytial virus G rapidly rec
247 doplasmic reticulum and Golgi apparatus from membrane-bound ribosomes were not translocated to the ro
248 emble the requirements of PAO, we considered membrane-bound Rieske-type oxygenases as potential candi
251 data demonstrate a cellular pathway whereby membrane-bound scavenger receptor type B-1 (SR-B1) in pa
252 Fibroblast Activation Protein (FAP) is a membrane-bound serine protease whose expression is often
253 oding approximately 100 million secreted and membrane-bound single-chain antibodies and identify anti
255 ical relevance, the structural nature of the membrane-bound state alphaS remains elusive, in part bec
256 the regulation of EHD2 oligomerization in a membrane-bound state is crucial to restrict caveolae dyn
261 human pigment synthesis are mediated by the membrane-bound, steroid hormone receptors G protein-coup
262 ized, to our knowledge for the first time, a membrane-bound stilbenoid-specific prenyltransferase act
263 an diseases, implies the formation of double-membrane-bound structures called autophagosomes (AP), wh
266 of the hairpin nature of NRG1 type III, two membrane-bound stubs with a type 1 and a type 2 orientat
268 ere, we use NMR spectroscopy to identify the membrane-bound surface of the S4S5 linker, and we show t
270 duces regulatory T cells that express latent membrane-bound TGF-beta (latency-associated peptide [LAP
272 (FVIIa), a trypsin-like serine protease, and membrane-bound tissue factor (TF) initiates blood coagul
274 shedding of TNF type I receptor (TNFR1), the membrane-bound TNFR1 C-terminal fragment is subsequently
277 esponse element-binding protein 3-like 1), a membrane-bound transcription factor that blocks cell div
278 Here we utilize amber codon suppression in a membrane-bound transporter protein to encode photocrossl
279 Its uptake into the cell is mediated by membrane-bound transporters and coupled to Na(+) transpo
282 viously reported that, upon irradiation, the membrane-bound tyrosine kinase receptor TIE2 translocate
283 ellular Chlamydia trachomatis replicate in a membrane-bound vacuole called inclusion, which serves as
284 [ACSL1 and ACSL3-6] translocates into the Ct membrane-bound vacuole, termed inclusion, and remains as
285 ation assays, we found that HPV resides in a membrane-bound vesicle until mitosis is completed and th
287 In nodule cells, bacteria are enclosed in membrane-bound vesicles called symbiosomes and different
288 cellular vesicles (EVs) are nanometer-sized, membrane-bound vesicles released by cells into the extra
291 doplasmic reticulum and actively exported in membrane-bound vesicles that are formed by the cytosolic
294 al positive-strand RNA viruses, replicate in membrane-bound viral replicase complexes in the cytoplas
295 viral factors affecting the formation of the membrane-bound viral replication complex is a major fron
298 ation of biological processes into discrete, membrane-bound volumes, is essential for cellular life.
299 rt (88% +/- 1%) of the antagonist uptake was membrane-bound, whereas 74% +/- 3% of the total receptor
300 TEMENT In this study, we identify MT3-MMP, a membrane-bound zinc protease, to be necessary for the de
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