ライフサイエンスコーパス: membrane-permeable

1 ted by subsequent addition of TPEN, which is membrane permeable.

2 perties of the peptides and making them more membrane permeable.

3 ferative effects, suggesting that hPL is not membrane-permeable.

4 the CA inhibitor, which is relatively slowly membrane-permeable.

5 182,780 but could be provoked using non-cell membrane-permeable 17beta-estradiol-BSA in all cells tes

6 We previously developed a class of membrane-permeable 2-aminoquinoline inhibitors and later

7 or stilbene disulfonate maleimide, SDSM) and membrane-permeable 7-diethylamino-3-(4'-maleimidyl)-4-me

8 vating intracellular cAMP levels with either membrane-permeable 8-Br-cAMP or an adenylyl cyclase acti

9 ergic agonist isoprenaline (1 microM) or the membrane-permeable 8-bromo-cAMP (2 mM) completely revers

10 Membrane-permeable 8-bromo-cAMP and the beta-adrenergic

11 Na2S enhanced CFTR stimulation by membrane-permeable 8Br-cAMP under inhibition of adenylyl

12 Jasplakinolide, a membrane-permeable actin-polymerizing and filament-stabi

13 n-1, 2-dioctanoylglycerol (DOG) were used as membrane permeable activators of protein kinases A (PKA)

14 mal fibroblasts, involving activation by the membrane-permeable adenosine analog 5-aminoimidazole-4-c

15 w that the antiproliferative effect of these membrane-permeable adenosine analogs is caused by transf

16 uncontrolled induction of PKA activity using membrane-permeable agonists is equally disruptive to gro

17 active presynaptic terminals, we find that a membrane permeable analog of cAMP enhances the number of

18 eralgesia produced by 8-bromo-cAMP (a stable membrane permeable analog of cAMP) or by forskolin (an a

19 Here we show that microinjection of a membrane-permeable analog of cAMP in lumbar dorsal root

20 , and the peptide effect was unaffected by a membrane-permeable analog of cAMP.

21 : the effect was mimicked by 8-bromo-cGMP, a membrane-permeable analog, and by sodium nitroprusside,

22 In addition, a membrane-permeable analog, CPT-cAMP, also opened BK(Ca)

23 th atrial natriuretic peptide (ANP) and with membrane-permeable analogs of cGMP would induce a net ap

24 n MS/DB neurons were insensitive to the cAMP membrane permeable analogue 8-bromo-cAMP (1 mM), and app

25 ylate cyclase and dibutyryl cAMP (dbcAMP), a membrane permeable analogue of cAMP suppressed JAK3 expr

26 inhibitor, and mimicked by 8-Br-cGMP, a cell-membrane permeable analogue of cGMP.

27 2+ entry by oleoyl-2-acetyl-sn-glycerol, the membrane permeable analogue of the Galphaq-phospholipase

28 8Br-cGMP (100 microM), a membrane-permeable analogue of cGMP, evoked a robust act

29 , 100, and 500 microg or 2.5 mg 8-Br-cGMP, a membrane-permeable analogue of cGMP, or 1 and 100 microg

30 pment of chemical entities including various membrane-permeable analogues of cAMP and newly discovere

31 ects of nitric oxide donors were mimicked by membrane-permeable analogues of cGMP.

32 re, cellular studies revealed that 1 is cell membrane permeable and effectively inhibits intracellula

33 r-soluble and, in many cases, were both more membrane permeable and more stable to liver microsomes t

34 cal microscopy experiments show that RCS1 is membrane-permeable and can sense changes in the levels o

35 y experiments establish that Cu(II)[BOT1] is membrane-permeable and can successfully signal the prese

36 tively with another building block, which is membrane-permeable and free in solution, to form the dip

37 idues of the alpha-subunit was assessed with membrane-permeable and membrane-impermeable Cys-directed

38 reted into the periplasm to oxidize the more membrane-permeable and toxic Cu(I) before it can enter t

39 are protease resistant, structurally rigid, membrane permeable, and capable of modulating protein-pr

40 ration-dependent, required the ligands to be membrane permeable, and was not the result of the revers

41 Systemic administration of a membrane-permeable antioxidant prevented oxidative stres

42 Preincubation of cells with membrane-permeable antioxidants, pyrrolidine dithiocarba

43 e myelogenous leukemia (AML), we studied the membrane-permeable arsenic compound phenylarsine oxide (

44 canning confocal microscopy show SPI is cell membrane-permeable, associates with the cytoplasmic tail

45 on Green diacetate succinimidyl ester, and a membrane-permeable base to raise intramitochondrial pH.

46 Membrane-permeable biarsenical compounds FlAsH and ReAsH

47 We have found that membrane-permeable bioagents can be rendered membrane im

48 ectable oligomers upon addition of AP1510, a membrane-permeable, bivalent FKBP ligand.

49 Specific inhibitors and membrane permeable blocking peptides were used to determ

50 lls with the inhibitors, which were rendered membrane permeable by attachment of an octaarginine sequ

51 ZO-1 (PDZ)-binding sequence of DAT, was made membrane-permeable by fusing it to the cell membrane tra

52 e whether stapled peptides are intrinsically membrane permeable, by performing a case study on a stap

53 ponse was induced by 1 nM TNF, the synthetic membrane-permeable C-2, C-6, and C-8 ceramides had no ef

54 Acetazolamide, a membrane-permeable CA inhibitor, was used to inhibit tot

55 rate that both transient Ca(2+) depletion by membrane-permeable Ca(2+) chelators and chronic blockage

56 taining either TTX, low Ca2+ plus Cd2+, or a membrane permeable Ca2+ chelator BAPTA-AM (when BAPTA wa

57 GS on mEPSCs, as did pertussis toxin and the membrane-permeable Ca2+ chelator 1,2-bis(2-aminophenoxy)

58 A membrane-permeable calcineurin inhibitor, however, still

59 Furthermore, the membrane-permeable calcium chelator BAPTA-AM had no effe

60 We find that treating cells with the membrane-permeable calcium chelator, 1,2-bis(2-aminophen

61 raacetic acid, tetra(acetoxymethyl)-ester, a membrane-permeable calcium chelator, inhibits MMS-induce

62 Membrane-permeable calmodulin inhibitors, such as the na

63 Studies with a selective membrane permeable calpain inhibitor indicated that tTG

64 acute hippocampal slices was prevented by a membrane-permeable calpain inhibitor.

65 ty in single muscle fibers was measured by a membrane-permeable calpain substrate.

66 Here we report that KN-93, a membrane-permeable CaMKII inhibitor, blocked glutamate-i

67 ypes affecting PMN excitability, we used the membrane permeable cAMP analog 8-bromo-cAMP (8-Br-cAMP)

68 bol 12-myristate 13-acetate (PMA), but not a membrane permeable cAMP analog induced rapid phosphoryla

69 pendent stimulation of I(Ca,T) by 8-Br-cAMP (membrane permeable cAMP analog) was abolished by siRNA d

70 ning various concentrations of 8-CPT-cAMP, a membrane permeable cAMP analog, for 2 h.

71 ats, and (3) the tachycardia elicited by the membrane permeable cAMP-analogue, 8-(4-chlorophenylthiol

72 n, an activator of adenylyl cyclases, and by membrane-permeable cAMP analog (dbcAMP), exhibit a bipha

73 hniques and have examined the effects of the membrane-permeable cAMP analog 8-(4-chlorophenylthio) (C

74 Furthermore, a membrane-permeable cAMP analog 8-(4-chlorophenylthio)-cA

75 The membrane-permeable cAMP analog 8-pcpt-cAMP also reduced

76 After bath application of the membrane-permeable cAMP analog adenosine 3',5'-cyclic mo

77 Consistent with this, a membrane-permeable cAMP analog and a cAMP-elevating agon

78 pid, occurring within 5 min of exposure to a membrane-permeable cAMP analog, indicative that threshol

79 ed by 2.5 to 25 nmol 8-bromo-cAMP (n = 4), a membrane-permeable cAMP analog.

80 proximately 4.5 h in cells stimulated with a membrane-permeable cAMP analog.

81 rons at relatively low concentrations of the membrane-permeable cAMP analogs (20-50 microM).

82 Bath application of the membrane-permeable cAMP analogs 8-bromo-cAMP (8-Br-cAMP)

83 Membrane-permeable cAMP analogs are reported to rescue t

84 ntly enhanced when A-kinase was activated by membrane-permeable cAMP analogs or when cells were cotra

85 selves but rather the hydrolyzed products of membrane-permeable cAMP analogs that prevent proliferati

86 activator forskolin as well as two cellular membrane-permeable cAMP analogs, dibutyryl cAMP and 8-br

87 lementing the preservation solution with the membrane-permeable cAMP analogue dibutyryl-cAMP resulted

88 Similar results were obtained with the membrane-permeable cAMP analogues dibutyryl-cAMP and 8-b

89 he effects of forskolin were not mimicked by membrane-permeable cAMP analogues.

90 The membrane-permeable cAMP derivative, 8-bromo cAMP (0.1 to

91 We have used synthetic membrane-permeable cathepsin substrates, which liberate

92 ng cGMP in cells by addition of 8-Br-cGMP (a membrane permeable cGMP analogue) did not reproduce the

93 Root exposure to 10 mum membrane permeable cGMP induced changes in abundance for

94 mimicked when cells were pre-treated with a membrane-permeable cGMP analog and blocked by pharmacolo

95 Treating cells with a membrane-permeable cGMP analog partly mimicked the effec

96 t in response to the extracellularly applied membrane-permeable cGMP analog pCPT-cGMP (50 muM), which

97 and detachment from the substratum and by a membrane-permeable cGMP analog, a known regulator of str

98 Bath application of the membrane-permeable cGMP analogs 8-bromo-cGMP (B-cGMP) an

99 onfluent monolayers were treated with ANP or membrane-permeable cGMP analogs in the presence of anant

100 NO donors on COX-2 mRNA expression; (b) the membrane-permeable cGMP analogue, 8-Br-cGMP, mimicked th

101 A membrane-permeable cGMP analogue, 8-Br-cGMP, mimics the

102 ion of vascular smooth muscle cells with the membrane-permeable cGMP analogues, dibutyryl cGMP and 8-

103 rongly buffering intracellular Ca2+ with the membrane-permeable chelator BAPTA-AM (10 microM) signifi

104 Chelation of Zn(2+) with the membrane-permeable chelator N,N,N',N'-Tetrakis(2-pyridyl

105 Using a membrane-permeable chelator of zinc or a mutant TRAF2 mo

106 (c) Membrane-permeable chelators stop but do not reverse enz

107 In contrast, filipin and other membrane-permeable cholesterol-binding agents (digitonin

108 Treatment of cells with membrane permeable CK1 inhibitor 3-[(2,3,6-trimethoxyphe

109 Chelating intracellular Ca2+ using the membrane-permeable compound BAPTA-AM, abolished the effe

110 Fic gives insights on membrane-permeable compounds in terms of cellular potenc

111 The proinhibitors are designed as neutral, membrane-permeable compounds that once inside the cell m

112 Membrane-permeable compounds that reversibly inhibit a p

113 ool, we have synthesized and characterized a membrane-permeable, copper-selective fluorescent sensor

114 e intermolecularly cross-linked by using the membrane-permeable cross-linker bis-maleimido hexane.

115 e we show, using CSD mutants (F92A/V94A) and membrane-permeable CSD-competing peptides, that Src kina

116 roine disulfonic acid (BCPD, 100 muM), a non-membrane-permeable Cu chelator.

117 Neither forskolin nor a membrane permeable cyclic adenosine monophosphate analog

118 PAF and PMA, as well as a membrane permeable cyclic AMP analog, stimulated phospho

119 Moreover, addition of membrane permeable cyclic nucleotides during growth assa

120 for the discovery of geometrically diverse, membrane permeable cyclic peptide scaffolds based on the

121 While neither epinephrine, forskolin, nor a membrane-permeable cyclic AMP analog induced reactivatio

122 A (PKA), phosphodiesterase 3B (PDE3B), and a membrane-permeable cyclic guanosine monophosphate (cGMP)

123 Exposure to the membrane-permeable cyclic nucleotide analogue CPT-cAMP e

124 macroscopic IRKC that was suppressed by the membrane-permeable cyclic nucleotide Sp-cAMP but was una

125 the EAAC1(-/-) mice with N-acetylcysteine, a membrane-permeable cysteine precursor.

126 1(-/-) mouse to evaluate N-acetylcysteine, a membrane-permeable cysteine pro-drug, as a potential dis

127 photoaffinity nucleotide analogue and a non-membrane-permeable cysteine-specific chemical cross-link

128 hole cytoplasmic tails, to the labeling of a membrane-permeable, cysteine-specific chemical biotin ma

129 l wall proteins were biotinylated with a non-membrane-permeable derivative to distinguish extracellul

130 Membrane-permeable DG also drove perilipin 4 and 5 onto

131 Treating cells with a membrane-permeable DG recruited perilipin 3 to the ER.

132 12-O-tetradecanoylphorbol-13-acetate or with membrane-permeable diacylglycerols also stimulated PKD a

133 Similarly, addition of membrane-permeable dibutyryl cAMP, like alpha-MSH, suppr

134 A membrane permeable DNA-associating vital dye, ethidium b

135 Inactivation of Nrf2 by antisense or by a membrane permeable dominant-negative polypeptide sensiti

136 due to steric hindrance, and addition of the membrane-permeable drug 4-hydroxytamoxifen (4-HT), which

137 broventricular perfusion in rats of the cell membrane-permeable dye diaminofluorescein-2/diacetate (D

138 f the mitochondrion relies on the use of the membrane-permeable dye, Oregon Green diacetate succinimi

139 lorofluorescein, fluorescent products of the membrane-permeable dyes hydroethidine and 2',7'-dichloro

140 ersal labelling method based on the organic, membrane-permeable dyes SiR and ATTO590 as Halo and SNAP

141 Isothiocyanates are membrane-permeable electrophiles that form adducts with

142 orneal endothelial cells were established on membrane-permeable filters.

143 ation initiated by addition of the bivalent, membrane-permeable FKBP dimerizer, AP1510, nearly double

144 teine tag that tightly binds the fluorescent membrane-permeable FlAsH ligand.

145 A tetracysteine motif that binds the membrane-permeable fluorescein derivative 4',5'-bis(1,3,

146 Coppersensor-1 (CS1) is a small-molecule, membrane-permeable fluorescent dye for imaging labile co

147 Calpain-mediated proteolysis of the membrane-permeable fluorescent substrate N-succinyl-L-le

148 enosine-3',5'-cyclic monophosphate (db-cAMP, membrane-permeable form of cAMP), the bell-shaped voltag

149 ntaining either ammonium chloride or E64d, a membrane-permeable form of E64, was added at various tim

150 Here we report that cell membrane-permeable forms of such peptides preferentially

151 A cell membrane-permeable fusion peptide derived from the uniqu

152 In addition, membrane-permeable Galpha(i2)- and Gbetagamma-blocking p

153 Instead, membrane-permeable gamma-secretase inhibitors, but not a

154 A membrane-permeable glutamate analog (dimethylglutamate [

155 the thiol-anti-oxidant N-acetyl-cysteine or membrane-permeable glutathione.

156 reen of 4,096 known compounds identified two membrane permeable GO inhibitors: dichromate salt and co

157 alysis of induction of GPIbalpha shedding by membrane-permeable GPIbbeta-derived peptides implicated

158 zed and externally functionalized by pendant membrane-permeable groups.

159 ence probes are unsuitable, we have designed membrane-permeable HMRef-betaGal, in which the optimized

160 ve transport involved the incorporation of a membrane permeable import function previously shown to c

161 oteins, remarkable for their ability to make membranes permeable in a temporally regulated manner.

162 of slices with calyculin A, a selective and membrane permeable inhibitor of protein phosphatases 1 a

163 Here we show that a novel membrane-permeable inhibitor of 14-3-3zeta-GPIbalpha int

164 Local application of okadaic acid, a membrane-permeable inhibitor of phosphatase 1 and 2A, to

165 A membrane-permeable inhibitor of protein kinase A, myrist

166 Both wortmannin and LY294002, membrane permeable inhibitors of phosphoinositide 3-kina

167 Inhibition of calpain with membrane permeable inhibitors or by expression of a domi

168 cells with fibroblasts was inhibited by cell membrane-permeable inhibitors of cathepsins B/L, but not

169 The specific, membrane-permeable inositol 1,4, 5-trisphosphate (Ins-1,

170 mGluR1/5 and NR2B glutamate receptors; (ii) membrane-permeable inositol 1,4,5-trisphosphate receptor

171 4,5-trisphosphate (InsP(3)) receptors with a membrane-permeable InsP(3) ester (InsP(3) BM) mimicked t

172 Pre-treatment with the membrane-permeable InsP3 receptor antagonist 2-APB block

173 The rate of cellular uptake of membrane-permeable, ionic fluorophores by THP-1 cells wa

174 plasmolysis, whereas a shock caused by outer-membrane permeable ions causes plasmolysis immediately u

175 Xe's represent a new class of potent, membrane permeable IP3 receptor blockers exhibiting a hi

176 A membrane-permeable iron chelator substantially reduces N

177 Rather, studies using a membrane-permeable iron chelator, salicylaldehyde isonic

178 p-regulated by desferrioxamine (DFO), a cell membrane-permeable iron chelator.

179 rotein domain (to permit dimerization by the membrane-permeable ligand AP20187) with or without a myr

180 the cytoplasm when the two are tethered by a membrane-permeable ligand.

181 Both membrane-permeable ligands like nicotine and much less p

182 PTEN-Long is a membrane-permeable lipid phosphatase that is secreted fr

183 om fractionated endosomes was assessed using membrane-permeable (luminol and lucigenin) and -impermea

184 CD30-targeting ADC delivering membrane permeable MMAE or pyrrolobenzodiazepine dimers

185 APB) has been extensively used recently as a membrane permeable modulator of inositol-1,4,5-trisphosp

186 interfering RNAs (siRNAs) conjugated to the membrane permeable molecule Penetratin to injured sensor

187 acid peptide that contains a lipophilic cell-membrane-permeable motif and a nuclear localization sequ

188 hich decreases the proportion of drug in the membrane-permeable neutral form.

189 The membrane-permeable, noncompetitive inositol 1,4,5-trisph

190 4-chlorophenylthio)-cyclic GMP (CPT-cGMP), a membrane-permeable, nonhydrolyzable analogue of cGMP, re

191 atives; pyrimidines, purine nucleotides, and membrane-permeable, nonhydrolyzable cyclic nucleotide an

192 The E. coli were labeled with a membrane-permeable nucleic acid stain (Syto15), a membra

193 Using the membrane-permeable nucleic acid stain SYTO 14, we direct

194 In this study, using membrane-permeable nucleotide analogs, we show that it i

195 ively, so that only the neutral radicals are membrane-permeable on the time scale of the transmembran

196 membranes using reductants that were either membrane-permeable or -impermeable.

197 reproduced by treating mesangial cells with membrane-permeable oxidants.

198 In contrast, a less membrane permeable payload, MMAF, failed to mediate byst

199 Consistent with this hypothesis, membrane-permeable pCPT-cAMP rescues the prolapse phenot

200 Herein, we use two membrane permeable peptide aldehyde protease inhibitors,

201 nhibitor of CaMKII, blocked run-up, as did a membrane permeable peptide corresponding to the CaMKII a

202 A membrane-permeable peptide (KV1-C peptide) corresponding

203 A membrane-permeable peptide containing residues 476-485 o

204 Notably, a plasma membrane-permeable peptide derived from GADD45-alpha, th

205 A 10-aa-long rhodamine-linked and membrane-permeable peptide inhibitor (PBP10) has such a

206 and Cx43, by genetic tagging of Cx43 or by a membrane-permeable peptide inhibitor that contains the C

207 We generated a membrane-permeable peptide mimetic of the PTPsigma wedge

208 Finally, treating myocytes with a membrane-permeable peptide representing beta(1)AR PDZ mo

209 ut myocytes is inhibited by treatment with a membrane-permeable peptide representing the beta2AR carb

210 Moreover, an exogenously applied membrane-permeable peptide that competes for Tau-vesicle

211 We found that a membrane-permeable peptide that disrupts mGluR5 interact

212 Thus, conjugated, membrane-permeable peptides are effective tools for the

213 strategy entails the delivery of conjugated membrane-permeable peptides that disrupt domain interact

214 Through use of a newly developed set of membrane-permeable peptides that separately inhibit eith

215 1 in wild-type mice, dominant negative Ets-1 membrane-permeable peptides were administered systemical

216 Using both siRNA and membrane-permeable peptides, we show that alphavbeta6-de

217 probed by weakening it in situ with urea, a membrane-permeable perturbant of spectrin.

218 in MCF-10A cells treated with DAG-lactone, a membrane permeable PKC activator.

219 erally resistant to high levels of these two membrane-permeable poisons.

220 The ester-protected analog DFSA (PDFSA) is a membrane-permeable precursor of DFSA designed to be used

221 Here we describe that cell membrane-permeable prodrugs of the complex II substrate

222 an be applied to targeting the activation of membrane permeable properties in mildly acidic pH enviro

223 ect effects of dopamine receptor ligands and membrane-permeable protein kinase ligands on ganglion ce

224 ssion in many clinically relevant pathogens, membrane-permeable quorum sensing antagonists that preve

225 Here, we investigate the effects of a membrane-permeable radical scavenger (tempol) on the cir

226 Intravitreal injection of membrane-permeable radical scavenger but not vehicle bef

227 single cysteine-containing mutants using the membrane-permeable reagent 3-(N-maleimidylpropionyl)bioc

228 e mitochondrial redox status and responds to membrane-permeable reductants and oxidants.

229 e live cell uptake properties of a dinuclear membrane-permeable Ru(II) cell probe show that, at low c

230 through a chemoenzymatic strategy to process membrane-permeable S-alkyl analogues of methionine (SAAM

231 by S-nitrosylation through exposure to cell membrane-permeable S-nitrosothiols and that sGC is S-nit

232 torial library, followed by deconvolution of membrane-permeable scaffolds to identify cyclic peptides

233 NMDA antagonist dizocilpine(MK-801) and by a membrane-permeable scavenger of ROS.

234 ent with the NMDA antagonist MK-801 and by a membrane-permeable scavenger ofROS.

235 accomplished by incorporating a hydrophobic, membrane-permeable sequence (MPS).

236 further development of potent, specific, and membrane-permeable SH2 domain inhibitors.

237 nsitive (HIDE) membrane probes, based on the membrane-permeable silicon-rhodamine dye HMSiR, that ass

238 In the present paper, we have used a novel membrane-permeable, small-molecule inhibitor of GRK2 and

239 Consistent with this interpretation, a membrane-permeable stabilizer of F-actin, jasplakinolide

240 e-2,2'-disulfonic acid (AMS) followed by the membrane permeable sulfhydryl reagent 3-(N-maleimidylpro

241 PDI and beta-actin could be abolished by the membrane-permeable sulfhydryl blocker, N-ethylmaleimide,

242 sponsible for methyl methanethiosulfonate (a membrane-permeable sulfhydryl modifier)-mediated enhance

243 An nNOS inhibitor or a membrane-permeable superoxide dismutase (SOD) mimetic pr

244 directly to TRPML1 and elicited by a potent membrane-permeable synthetic agonist, is dramatically re

245 wing mutant seedlings in the presence of the membrane-permeable synthetic auxin, 1-naphthaleneacetic

246 nt of physiological levels of ZAP70 with the membrane-permeable synthetic ligand FK1012A leads to rap

247 ition of PC cleavage in PC12 cells using the membrane-permeable synthetic peptide chloromethyl ketone

248 ently-acting Runx1.d190, we generated a cell membrane-permeable TAT-Runx1.d190 fusion protein.

249 point mutants, and specific inhibition by a membrane-permeable TAT-V peptide--we demonstrate that th

250 oxaz is stable in human plasma and is poorly membrane permeable, thereby limiting activation to local

251 nal domains of these subunits, we utilized a membrane permeable, thiocleavable cross-linking reagent

252 otein which may render the T. pallidum outer membrane permeable to nutrients while remaining inaccess

253 trations of digitonin to render their plasma membrane permeable to succinate, ADP, safranin O, and ot

254 '-deoxyriboside (MeP-dR) to the highly toxic membrane permeable toxin, 6-methylpurine (MeP).

255 le ascorbate/TMPD was 1.23 times that of the membrane permeable ubiquinol.

256 Moreover, we show that a cellular membrane permeable version of the peptide corresponding

257 To generate a membrane-permeable version of the anti-Akt1 scFv, the sc

258 uorescence was quenched by the addition of a membrane-permeable weak base, methylamine.

259 able in vivo conditions, SMTA is found to be membrane-permeable while SSETA is not.

260 nt of human T lymphocytes with a recombinant membrane-permeable YopH resulted in severe reduction in

261 eatment of the human Jurkat T-cell line with membrane permeable zinc chelators disrupts CD4.p56(lck)

262 Using the membrane-permeable zinc chelator, N,N,N',N'-tetrakis-(2-