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1 and pigment-pigment interactions within the membrane-spanning region.
2 f ion flux have been identified flanking the membrane-spanning region.
3 electrons to QFR by binding directly to the membrane-spanning region.
4 d form and of an inactive mutant lacking the membrane-spanning region.
5 the formyl peptide binding site maps to the membrane-spanning region.
6 y extending from the cytosolic side into the membrane-spanning region.
7 that it is anchored in the membrane by this membrane-spanning region.
8 x contains two aspartic acid residues in the membrane-spanning region.
9 ains a potential signal peptide and a single membrane-spanning region.
10 ne/glutamine-rich C terminus and 3 potential membrane spanning regions.
11 TolQ is a polytopic protein with three membrane-spanning regions.
12 eins of the endoplasmic reticulum with eight membrane-spanning regions.
13 p42, gH, and gL were expressed that lack the membrane-spanning regions.
14 etic) alcohol doses, defined by mutations in membrane-spanning regions.
15 a protein that is predicted to contain seven-membrane-spanning regions.
16 only 3% of the residues in the proteome form membrane-spanning regions.
17 protein is predicted to have 8 instead of 12 membrane-spanning regions.
18 residues in S. typhimurium with 12 possible membrane-spanning regions.
19 o the Golgi apparatus via the amino-terminal membrane-spanning regions.
20 to experimentally define the presence of six membrane-spanning regions.
21 ir lipid moieties and integral proteins with membrane-spanning regions.
22 es SREBPs in the ER luminal loop between two membrane-spanning regions.
23 minal sequences which include four predicted membrane-spanning regions.
24 ino acid sequence domains, and six predicted membrane-spanning regions.
25 ermore, a deletion construct containing only membrane-spanning regions 5 and 6 oligomerized to a simi
27 ng pathogen-associated molecular patterns, a membrane spanning region and an intracellular Toll/Inter
28 ino acid sequence indicates that HIP lacks a membrane spanning region and has no consensus sites for
29 of 63 amino acids that is C-terminal to the membrane spanning region and nonessential for Tlg2p func
30 olecular weight of 26,693 with two potential membrane spanning regions and a likely C-terminal endopl
31 eptide that contains at least five potential membrane spanning regions and a presumptive NADPH bindin
32 the photoaffinity ligands occurs in or near membrane spanning regions and delineates the maximum pos
33 1 and TAP2 contain an N-terminal hydrophobic membrane-spanning region and a C-terminal nucleotide bin
34 al domains: an N-terminal protease, a middle membrane-spanning region and a soluble C-terminal region
36 ), located extracellularly between the first membrane-spanning region and the pore, is conserved amon
37 s embedded in the plasma membrane with seven membrane-spanning regions and a required intracellular C
39 bunit interactions mediated through both the membrane-spanning regions and residues 2629-2654 of the
40 no acids 288 to 376) contains three putative membrane-spanning regions and shows a high degree of ami
41 oded a 456-residue protein with 11 potential membrane-spanning regions and two consensus sites for N-
42 ollowed by extracellular Leu-rich repeats, a membrane spanning region, and a short cytoplasmic carbox
43 ximately 100-amino acid domain, six putative membrane spanning regions, and three copies of the mitoc
44 teractions between the cytoplasmic tail, the membrane-spanning region, and the ectodomain of the prot
45 a hydrophobic protein with seven hydrophobic membrane-spanning regions, and AdcA is a lipoprotein per
46 d that both the signal peptide and the first membrane-spanning region are required for insertion of t
48 embrane alpha-helical proteins, in which the membrane-spanning regions are made up of alpha-helices.
49 he Jaw1 protein, which contain a hydrophobic membrane spanning region, are sufficient to target a het
50 ve components and define the fifth and sixth membrane spanning regions as the key determinants in rec
51 antagonist probe deep within the receptor's membrane-spanning region at Leu(88), a residue within tr
54 cks its extracellular domain but retains its membrane-spanning region becomes proteolytically process
55 e-spanning proteins contain both aqueous and membrane-spanning regions, both of which contribute to f
58 -terminal region and is linked to the fourth membrane-spanning region by a loosely structured tetheri
60 irB6 with the exiting T-strand; (ii) a multi-membrane-spanning region carboxyl-terminal to loop P2 (r
61 of NarK2 structure is proposed containing 12 membrane spanning regions consistent with other members
62 acellular loop three and its adjoining trans-membrane-spanning regions contain elements essential for
63 EFECTIVE KERNEL1 (DEK1), which consists of a membrane-spanning region (DEK1-MEM) and a calpain-like C
65 ragments of Spt23p and Mga2p that lack their membrane-spanning regions (Deltatm) were expressed under
67 a 339-amino acid protein with six potential membrane-spanning regions flanked by hydrophilic amino-
68 s the first demonstration that these unusual membrane-spanning regions found in the caveolin family p
69 eyond the R-peptide cleavage site toward the membrane-spanning region had no additional effect on the
72 well-defined active site cavities within the membrane-spanning region in each monomer interface of th
74 Previous studies have shown that of the six membrane-spanning regions in each subunit, the 5th and 6
76 airpin loop," formed by the second and third membrane-spanning regions, insert in the absence of func
77 drial intermembrane-facing surface, with six membrane-spanning regions interspersed by two intermembr
78 atase function of SpoIIE nor the N-terminal, membrane-spanning region is needed for the switch to asy
79 e pathway that connects the cytoplasm to the membrane-spanning regions is unknown, and functional rol
81 b, a conformationally active protein with 11 membrane-spanning regions, loses function due to decreas
82 subunit, with junctions located between the membrane-spanning regions M2 and M3, in the middle of M2
83 lock is conferred by a residue in the second membrane-spanning region (M2), which is alanine in the a
84 Many of these receptors contain multiple membrane-spanning regions, making their purification and
85 TAP1 and TAP2, each containing a hydrophobic membrane-spanning region (MSR) and a nucleotide binding
86 ate peroxidase (APX) with a single, putative membrane-spanning region near the C-terminal end of the
87 ain that is quite similar in sequence to the membrane spanning region of the rate controlling enzyme
88 introduced at selected positions within the membrane-spanning region of acetyl-GGALW(5)LALALAL(12)AL
91 l evidence that the cytoplasmic tail and the membrane-spanning region of Env can influence the overal
92 eplacement of the conserved cysteines in the membrane-spanning region of GP(2) was found to depend on
94 brane helix of SREBP-2 was replaced with the membrane-spanning region of the low density lipoprotein
95 his truncated form corresponds to the entire membrane-spanning region of the protein and is similar t
96 omain was localized to a proposed N-terminal membrane-spanning region of VirB4, as shown by the domin
97 ree conserved histidine residues in presumed membrane-spanning regions of CP43, His40, His105, and Hi
99 , thus leading to efficient labelling of the membrane-spanning regions of the protein upon irradiatio
100 protein-coupled receptors is embedded in the membrane-spanning regions of these receptors, whereas th
101 amino-terminal extracellular domain and four membrane-spanning regions, one of which forms a wall of
103 The fusion containing the second and third membrane-spanning regions required the membrane potentia
104 is regulated by a beta subunit that has two membrane-spanning regions separated by an extracellular
106 lysis indicated that Tap1 had no significant membrane spanning regions, suggesting that it resides pr
107 er with two S5 residues in the middle of the membrane-spanning regions, supporting a model in which t
108 nces predicted protein structures with seven membrane spanning regions that have strong conservation
109 beta-sheet was also identified close to the membrane-spanning region that resembles the cytoplasmic
110 a large superfamily of receptors with seven membrane-spanning regions that activate the G proteins,
112 t a conserved glutamine residue in the first membrane-spanning region (TM1 region) of the alpha subun
113 nt migration entails a net shift from apolar membrane spanning regions to more polar regions of the p
114 as isolated domains, or are fused through a membrane-spanning region to methyl-accepting chemotaxis
115 changes a threonine in the receptor's sixth membrane-spanning region to proline (T410P) was identifi
116 topology of the type-1 InsP(3)R, a series of membrane-spanning region truncation and deletion plasmid
118 rane potential for insertion while the first membrane-spanning region was able to insert even in the
119 A 15-20-residue segment C-terminal to the membrane-spanning region was found to be highly resistan
120 pu activity is associated primarily with its membrane-spanning region, we have determined that the HI
121 brane assembly of TolQ, fusions of different membrane-spanning regions were examined for their abilit
123 otein components revealed that the first two membrane-spanning regions were necessary for membrane ta
124 Each TAP subunit contains an N-terminal membrane-spanning region with multiple membrane-spanning
126 in the inner ear, CTL2 contains 10 predicted membrane-spanning regions with multiple N-glycosylation
127 y lipoprotein receptor (LDLR), including its membrane spanning region, without altering either the sp
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