ライフサイエンスコーパス: memory B-cell

1 PCs with repopulation from clonally related memory B cells.

2 i.e., activated memory cells and tissue-like memory B cells.

3 IV increased frequencies of plasmablasts and memory B cells.

4 ) PBs, and CD20(+)CD27(+)CD38(lo/int)CD43(-) memory B cells.

5 27(+) B cells--are post-germinal center (GC) memory B cells.

6 PPE1 enhanced IgE also in human memory B cells.

7 dependent on protection by pathogen-specific memory B cells.

8 for the long-term maintenance of Ag-specific memory B cells.

9 n and the development of active autophagy in memory B cells.

10 e in both the proportion and number of CD27+ memory B cells.

11 allows age-dependent accumulation of resting memory B cells.

12 body responses, long-lived plasma cells, and memory B cells.

13 ace over time after the initial formation of memory B cells.

14 re CD5(+), IgM(+) memory, and class-switched memory B cells.

15 ory receptor expressed by a subpopulation of memory B cells.

16 to naive B cells and to IgM-only and IgG(+) memory B cells.

17 T cell-independent CD27(-)IgA(+) circulating memory B cells.

18 and associated with an increased fraction of memory B cells.

19 a cells, but not circulating plasmablasts or memory B cells.

20 differentiation to produce plasma cells and memory B cells.

21 ndent accumulation of class-switched resting memory B cells.

22 eks, facilitating Ag presentation to cognate memory B cells.

23 ression; and the ability to generate optimal memory B cells.

24 ed and T regulatory cells and also naive and memory B cells.

25 artment of IgM(+)(IgD(+)) and class-switched memory B cells.

26 cells, antibody-secreting plasma cells, and memory B cells.

27 reting cells, as well as germinal center and memory B cells.

28 clones, especially among non-class-switched memory B cells.

29 matic hypermutation, and differentiated into memory B cells.

30 ciated with reduced frequency of circulating memory B-cells.

31 anisms, unmasking CD22 relative to naive and memory B-cells.

32 apy), decreased percentages of IgM+CD21-/low memory B cells (35.7% +/- 6.1% before therapy vs 14.9% +

33 These memory B cells adoptively transferred into naive mice wi

34 nd avidities of IgG and lower frequencies of memory B cells against Expanded Program on Immunization

35 Reactivation of memory B cells allows for a rapid and robust immune resp

36 isolation and characterization of AHAs from memory B cells, although anti-hinge-reactive B cells wer

37 ively associated with proportions of CD27(+) memory B cells among farmers' children and inversely rel

38 cquired phenotypes of atypical and classical memory B cells and 9G4(+) IgG contained equivalent numbe

39 nal center reaction, and they developed into memory B cells and Ab-secreting cells that were capable

40 sponses due to the production of Ag-specific memory B cells and Ab-secreting plasma cells.

41 atients with severely reduced class-switched memory B cells and an elevated level of CD21(lo) B cells

42 ers and found to have reduced frequencies of memory B cells and antigen-specific antibody-secreting c

43 al profile was equally dissimilar to healthy memory B cells and circulating B cells likely due increa

44 numbers were normal, but the proportions of memory B cells and EBV-specific effector memory CD8(+) T

45 rial, we sorted hemagglutinin cross-reactive memory B cells and identified three antibody classes, ea

46 allergen exposures that recurrently activate memory B cells and identify these as a therapeutic targe

47 , including not only memory T cells but also memory B cells and innate memory cells.

48 donors) MHC-II expression as class-switched memory B cells and intermediate costimulatory molecule e

49 e associated with a significant reduction in memory B cells and no evidence of circulating antibody-s

50 show that the Env-specific circulating IgG, memory B cells and plasma cells displayed similar kineti

51 r affinity maturation and the development of memory B cells and plasma cells, while regulatory CD4(+)

52 erminal centers leading to the generation of memory B cells and plasma cells.

53 ons of activated mature B cells, tissue-like memory B cells and plasmablasts, and low proportions of

54 human B cells, with a focus on HIV-specific memory B cells and plasmablasts/cells that are responsib

55 The patients also display few memory B cells and poor antibody responses.

56 lele induced haploinsufficiency in naive and memory B cells and recapitulated abnormal immunologic fe

57 also significantly increased class switched memory B cells and serum immunoglobulin G (IgG).

58 olecules involved in the interaction between memory B cells and T follicular helper (Tfh) cells.

59 correlation between numbers of IgM+CD21-/low memory B cells and T-regulatory cells (P = .03), and pos

60 t they represent germinal center-derived IgM memory B cells and that IgM memory and MZ B cells consti

61 o postinfection the proportion of IgG2a/c(+) memory B cells and the systemic levels of lymphocytic ch

62 here was a corresponding increase in IgG1(+) memory B cells and virus-specific IgG1 Abs.

63 y selection thresholds on cells entering the memory B-cell and plasma cell pools, as exemplified by t

64 were measured in the blood (plasmablasts and memory B cells) and in the bone marrow (plasma cells).

65 or induction of cross-reactive plasmablasts, memory B cells, and cytokine-secreting CD4(+) and CD8(+)

66 ctivated B cells and circulating tissue-like memory B cells, and expansion of the B regulatory cells

67 ed frequencies of plasmablasts, PLA-specific memory B cells, and IL-10-secreting CD73(-) CD25(+) CD71

68 cells, in contrast to mature naive B cells, memory B cells, and plasmablasts, were hypersensitive to

69 n affects allospecific and pathogen-specific memory B cells, and reason that these investigations can

70 high-affinity IgG, switching to IgG2c, early memory B cells, and recall antibody responses.

71 expression of Bcl-6, the frequency of GC and memory B cells, and secondary Ab responses.

72 activated memory and CD27(+)CD21(+) resting memory B cells, and subphenotypes with novel patterns of

73 numbers of naive CD8(+) T cells and switched memory B cells, and TH1/TH2 cytokine imbalance improved

74 ted with SIV Env-specific rectal IgA, rectal memory B cells, and total rectal plasma cells.

75 ed rare affinity-matured human NANP-reactive memory B cell antibodies elicited by natural Pf exposure

76 After purification, antigen-specific mouse memory B cells are first single-cell-sorted by fluoresce

77 and CD8(+) T lymphocytes as well as switched memory B cells are mostly targeted by the injection-only

78 Memory B cells are presumably more responsive due to hig

79 cades downstream of the BCR are blocked, and memory B cells are temporarily silenced, preventing them

80 this B-cell subset, this establishes IgM(+) memory B cells as a general target of lymphoproliferatio

81 stress is involved in optimal expression of memory B cells, as demonstrated in CD4(+) T cells.

82 gative patients, P=0.0008) at the expense of memory B cells, as were BAFF serum levels (1,651 +/- 1,2

83 igh number of circulating 6BPS IgG-secreting memory B cells at baseline.

84 ugh cognate interactions between T cells and memory B cells (B(mem)) are essential for the secondary

85 Peripheral CD27(+) memory B-cells become quantitatively reduced and dysfunc

86 ction of neutralizing antibody (Ab)-encoding memory B cells (Bmem cells).

87 -IL-7 improved the percentages of long-lived memory B cells (Bmem) in the draining LNs and plasma cel

88 of serotype-specific plasma cells (PCs) and memory B-cells (Bmems) as potential predictors of long-t

89 milarity of IgM(+)(IgD(+))CD27(+) and IgG(+) memory B cells but also pointed at distinct functional c

90 s not critical for the initial generation of memory B cells but is required for their long-term persi

91 NV-specific memory B cells but not antibody-secreting cells persiste

92 BTB32 is highly expressed by mouse and human memory B cells but not by their naive counterparts.

93 stent high-affinity functional Ab titers and memory B cells, but how it really shapes the Ag-specific

94 indicate that naturally acquired PS-specific memory B cells, but not levels of circulating IgG at tim

95 In contrast, SHM reduced the longevity of memory B cells by creating polyreactive specificities th

96 reveals a functional plasticity of human IgM memory B cells by showing their propensity to undergo se

97 ptosis could be transferred to healthy donor memory B-cells by co-culturing these cells with plasma f

98 istic of plasmablasts, and transitioned into memory B cells (CD38(-)CD27(+)) at the early convalescen

99 numbers of T-regulatory cells, IgM+CD21-/low-memory B cells, CD4+CXCR5+ interleukin 21+ cells, and T-

100 production and find that two subsets of IgG1 memory B cells, CD80(+)CD73(+) and CD80(-)CD73(-), contr

101 In conclusion, this study substantiates memory B-cell characteristics of human IgM(+)IgD(+)CD27(

102 tated sequences, suggesting similarity among memory B-cell clonal lineages.

103 ass composition, with particular patterns of memory B-cell clone generation in GC reactions.

104 roduce amazingly large, complex, and diverse memory B-cell clones, equipping the human immune system

105 spleen and bone marrow IgG plasma cells and memory B cells, compared with controls.

106 contrast, the interrogation of the quiescent memory B cell compartment is technically more challengin

107 ition and intraclonal diversity of the human memory B-cell compartment and the relationship between m

108 Depletion of the memory B-cell compartment contributes to the immunosuppr

109 xpanded clones, demonstrating that the human memory B-cell compartment is characterized by many, ofte

110 We show that the memory B-cell compartment is impaired among patients wit

111 ) B cells appeared in classical and atypical memory B cell compartments in African children and adult

112 Vaccine-induced memory B cell counts were significantly increased, and t

113 between B-cell/T-cell ratio and nonswitched memory B-cell counts (r = 0.42, P = .03).

114 ) transitional and CD19(+)CD24(-)CD38(-) new memory B-cell counts were higher in patients with AD ver

115 CVID) present with severely reduced switched memory B-cell counts, and some display an increase of CD

116 he rare ITGAM variants have reduced switched memory B-cell counts.

117 yields of IgE(+) cells compared to naive and memory B-cell cultures.

118 lop carriage, the number of circulating 6BPS memory B cells decreased and the number of 6BPS plasma c

119 in rhesus macaques for years after sustained memory B cell depletion.

120 .277] 10 cells/L) and selective depletion of memory B cells despite normal B cell survival ligand con

121 mote aberrant GC responses with autoreactive memory B cell development and plasma cell-derived autoan

122 of CD23 after undergoing isotype switch and memory B-cell differentiation.

123 In this study, we show that newly generated memory B cells do not display active autophagy but are c

124 (+)38(hi) B cells or PBs, but differ in that memory B cells do not express Ab secretion-related genes

125 ed by loss of naive B cells, loss of resting memory B cells due to their redistribution to the gut, i

126 There was higher activation of memory B cells early during acute secondary infection, s

127 These data provide evidence that memory B cell evolution can expand the HA subtype specif

128 Phospholipase A2-specific IgG4-switched memory B cells expanded after bee venom exposure.

129 Human naive and memory B-cells express sulfated glycans as high affinity

130 We provide evidence that in primary memory B cells, expression of FCRL4 leads to increased e

131 body region of single antigen-specific mouse memory B cells for antibody production.

132 nses, as neither long-lived plasma cells nor memory B cells form for months after infection, and nons

133 centers (GCs) are required for high-affinity memory B cell formation; however, the signals that commi

134 Consistent increases in circulating memory B-cell frequencies after receipt of the IIV refle

135 SV-specific peripheral blood plasmablast and memory B-cell frequencies and antibody longevity.

136 nes that augment B-cell responses and higher memory B-cell frequencies correlate with stronger respon

137 we observed decreased frequencies of SHM in memory B cells from AD-AID patients and AID+/- subjects,

138 Sequencing of the switch regions of memory B cells from European blood donors revealed frequ

139 cell repertoire but are rarely found in IgG memory B cells from healthy individuals.

140 We previously showed that memory B cells from relapsing-remitting multiple scleros

141 Analysis of memory B cells from the immunized macaque suggests that

142 Analysis of sorted CD27+ memory B cells from these patients revealed that this po

143 While memory B-cells from cirrhotic patients were resistant to

144 Using isolated naive and memory B-cells from patients with cirrhosis and age-matc

145 ter re-infection, somatically mutated IgM(+) memory B cells function as first responders by rapidly d

146 llicular helper (pTfh) cells correlated with memory B-cell function and influenza A(H1N1) antibody ti

147 ect memory B cells, leading to inhibition of memory B-cell function and persistent HCV infection in H

148 linked immunosorbent assay, and frequency of memory B cells, functional T-cell responses, and antigen

149 Low vaccine responders generated fewer memory B cells, had reduced activation by CD4(+) and CD8

150 Following the fate of antigen-specific memory B cells has been difficult.

151 ing clear, as in some patients, HLA-specific memory B cells have been shown to be present in the abse

152 ental models are providing new insights into memory B cell heterogeneity with respect to their phenot

153 ed single B cell analysis to interrogate the memory B cell Ig repertoires from two rhesus macaques af

154 Frequencies of AF DENV(+) class-switched memory B cells (IgD(-)CD27(+) CD19(+) cells) reached up

155 of total memory (CD27(+)) and class-switched memory B cells (IgM(-)) were significantly reduced in pa

156 cells and total and NV-specific IgA and IgG memory B cells) immune responses following infection.

157 y of gp41-reactive memory B cells than gp120-memory B cells in adult and neonatal RMs.

158 ies on antigen-dependent activation of human memory B cells in culture.

159 investigate the function of subsets of IgG1 memory B cells in IgE production and find that two subse

160 FcgammaRs, and BAFF during the formation of memory B cells in mice.

161 CD27(+)) and resting (CD19(+)CD27(+)CD21(+)) memory B cells in parallel to increased naive (CD19(+)CD

162 cell tetramer to define Plasmodium-specific memory B cells in parasite-infected mice and demonstrate

163 revealed increased numbers of blood IgG4(+) memory B cells in patients with IgG4-RD.

164 cell subsets and frequencies of Ag-specific memory B cells in peripheral blood from HIV-infected chi

165 a higher number of circulating Env-specific memory B cells in peripheral blood of AGMs than in the b

166 cross-reactive antibodies derived from blood memory B cells in RMs as observed in the HVTN 505 vaccin

167 increases in the numbers of antigen-specific memory B cells in spleens and plasma cells in bone marro

168 Pre-existing memory B cells in these children differentiated quickly

169 However, CD19(+)CD27(+) memory B cells in vivo seem to utilize only the IL-15/IL

170 We conclude that peripheral CD27(+) memory B-cells in cirrhosis exhibit increased sensitivit

171 ll dysfunction (defined by loss of total and memory B cells, increased B regulatory cell [Breg] count

172 ver, only delayed reconstitution of switched memory B cells, independent of immunosuppressive treatme

173 provide strong evidence for the existence of memory B-cell-independent, long-lived PCs in humans that

174 -product relationships with CD27(+) switched memory B cells, indicating that they represent germinal

175 expression between naive and class-switched memory B cells, indicating their potential to induce (pr

176 heories that reactivation/differentiation of memory B cells into plasma cells is required to sustain

177 gE and the clonal selection of high affinity memory B cells into the plasma cell fate, our findings p

178 nally, we show that the survival of existing memory B cells is dependent on Syk.

179 In addition, HA-specific memory B cells isolated from human peripheral blood were

180 oth infants and toddlers upon infection, and memory B cells isolated from individuals who previously

181 ptor B7.2 enabled lymphotropic HCV to infect memory B cells, leading to inhibition of memory B-cell f

182 h a low degree of maintenance at both PC and memory B cell levels in patients in remission.

183 mmunological memory is more effective during memory B cell maintenance stage.

184 disease relevant genes, as for instance the memory-B cell marker CD27 and PTPRC genes, providing us

185 Recent studies characterizing memory B cell (MBC)-derived MAbs have provided valuable

186 similar B-blasts can differentiate to become memory B cells (MBC), in which EBV persistence is establ

187 long-lived plasma cells and rapidly reactive memory B cells (MBC).

188 c B cells expressed an activated (CD21(low)) memory B-cell (MBC) phenotype.

189 Memory B-cell (MBC) responses were assessed.

190 Antibody-secreting cell (ASC) and memory B-cell (MBC) responses were enumerated in tonsils

191 ate into antibody-secreting cells (ASCs) and memory B cells (MBCs) after infection or vaccination.

192 pic overexpression of FOXP1 in primary human memory B cells (MBCs) and B-cell lines, combined with ch

193 the signals that control differentiation of memory B cells (MBCs) and long-lived plasma cells (LLPCs

194 associated with a large increase in atypical memory B cells (MBCs) that resemble B cells expanded in

195 We comprehensively review memory B cells (MBCs), covering the definition of MBCs a

196 of Ab immunity, long-lived plasma cells and memory B cells (MBCs), is remarkably inefficient, requir

197 ortion of total atypical and total activated memory B cells (MBCs).

198 However, Zbtb32(-/-) memory B cell-mediated recall responses occur more rapid

199 Although memory B cells (memBcs) are key players in humoral defen

200 al antibody (N-mAb) 26D1 was isolated from a memory B cell of a human vaccinee.

201 We cloned one of these antibodies, 3H3, from memory B cells of a healthy individual using a hybridoma

202 clones were seen predominantly among IgM(+) memory B cells of all HCV-infected patients analyzed.

203 The demonstration of gp41 immunodominance in memory B cells of both adult and neonatal RMs indicated

204 (mAbs) specific for LASV glycoproteins from memory B cells of Lassa fever survivors from West Africa

205 ymphomas, was specifically seen among IgM(+) memory B cells of the patients.

206 nasal wash, PspA-specific, or PspC-specific memory B cells or plasma cells.

207 output from the GC with differentiation into memory B cells or plasma cells.

208 OR] = 1.34, 95% CI 1.14-1.57; p < 0.001) and memory B cells (OR = 1.18, 95% CI 1.0-1.39; p = 0.04) we

209 g-induced Ig class-switched and IgM-positive memory B cells over 402 d.

210 01), but higher proportions of IgM+CD21-/low memory B cells (P < .05), CD4+IFNgamma+ cells (P < .01),

211 subsets, including a significant decrease in memory B cells, particularly of marginal zone (MZ) B cel

212 ew sex differences were seen in Env-specific memory B cell, plasmablast, or plasma cell frequencies i

213 rther suggest that establishing an optimized memory B cell pool should be an aim of 'universal' influ

214 pients had an impaired reconstitution of the memory B-cell pool.

215 We identified the CD19(+)CD27(+) memory B cell population as the major source of IL-10(+)

216 samples from the same study, we investigated memory B cell population dynamics in blood, bone marrow,

217 dividuals, particularly in the IgD(-)CD27(-) memory B-cell population in ACPA(+) RA.

218 ue VH and VL sequences from sorted naive and memory B cell populations.

219 ic, and PspC-specific IgG and IgA plasma and memory B-cell populations before and 7, 14, and 35 days

220 i and compare the proportion of Env-specific memory B-cell populations to that of HIV-infected humans

221 ns is not dictated by the composition of the memory B cell precursor pool.

222 ll differentiation, whereas activated IgG(+) memory B cells preferentially showed a plasma cell (PC)

223 ated shared clones between gut PCs and blood memory B cells, primarily IgAs.

224 Because normal memory B cells proliferate vigorously to ODN+IL-15, a cy

225 ntage for donor-derived T cells and switched memory B cells promoted restoration of cellular and humo

226 e binding site of CD22 relative to naive and memory B-cells, promoting recognition of trans ligands.

227 w production of antibody-secreting cells and memory B cells recognizing that strain upon revaccinatio

228 Evaluation of switched memory B cell recovery after rituximab may be useful for

229 g-term immunity, the life span of individual memory B cells remains poorly defined.

230 also important for the initial formation of memory B cells remains unclear.

231 Thus, both the preexisting memory B cell repertoire and serological antibody levels

232 ge-scale abnormalities in both the naive and memory B cell repertoires.

233 nstrated that 93% of HIV-1-reactive Abs from memory B cells responded to Env gp41.

234 re available that allow the interrogation of memory B cell response to pathogen re-encounter.

235 erotype-specific IgG, opsonophagocytosis, or memory B-cell response at either time point between chil

236 upon oronasal challenge and congruent with a memory B-cell response.

237 -cell compartment in terms of frequencies of memory B cells, response to in vitro stimulation, and ma

238 Memory B cell responses are more rapid and of greater ma

239 Memory B cell responses are vital for protection against

240 fundamental questions about antigen-specific memory B cell responses, as well as for characterizing a

241 k defines a new role for FcgammaRs in GC and memory B cell responses.

242 on the mechanisms of antibody production in memory B cell responses.IgE is an important mediator of

243 onophagocytosis for 8 vaccine serotypes, and memory B-cell responses for 18 serotypes before and afte

244 cell responses were biased toward IgA, while memory B-cell responses were biased toward IgG.

245 by a hemagglutination inhibition assay, and memory B-cell responses were evaluated by an enzyme-link

246 notype and functional properties of adaptive memory B-cell responses.

247 e did result in decreased TACI expression on memory B cells, resulting in impaired activation and ant

248 pothesized that the disappearance of CD27(+) memory B-cells results from enhanced sensitivity to apop

249 01 human V region expressed in vivo by human memory B cells revealed that the focus of mutations in c

250 ing-based repertoire analysis of circulating memory B cells reveals evidence for convergent selection

251 Naive and memory B cells showed a highly similar lncRNA expression

252 Importantly, Fas-deficient switched memory B cells showed increased rates of somatic hypermu

253 Class-switched memory B cells showed: accumulation of FAS-mutated B cel

254 g of the BCR from E2-specific class-switched memory B cells sorted from two independent participants

255 r 2 virus NAb responses, we performed single memory B cell sorting from the peripheral blood of a rhe

256 on, followed by the contraction, of a single memory B cell SPADE cluster was positively correlated wi

257 re-expansion of a pre-existing population of memory B cells specific for stem epitopes.

258 T cells, spontaneous Ab secreting cells and memory B cells specific to influenza hemagglutinin were

259 Reconstitution of all memory B cell subpopulations, number of immunosuppressiv

260 ic infections with regard to dynamics of the memory B cell subsets point to their role in the pathoge

261 te total and mature B cell recovery, whereas memory B cell subsets remained significantly depleted.

262 e highly similar to each other and to IgG(+) memory B cell subsets, with typical upregulation of acti

263 ell compartment and the relationship between memory B-cell subsets is still limited, although these a

264 among the four main human IgM(+) and IgG(+) memory B-cell subsets.

265 cted groups had lower proportions of resting memory B cells than did community controls.

266 elicited a higher frequency of gp41-reactive memory B cells than gp120-memory B cells in adult and ne

267 xpression, B-1 cells align more closely with memory B cells than with 20(+)38(hi) B cells or PBs, but

268 yet little is known about the properties of memory B cells that are central to the recall alloantibo

269 to have a higher proportion of Env-specific memory B cells that are mainly gp120 directed.

270 n of virus-specific B lymphocytes, including memory B cells that differentiate into ASC soon after co

271 zing antibody titers have expanded clones of memory B cells that express the same immunoglobulin VH3-

272 asked a marked, long-term depletion of CD19+ memory B cells that may underpin efficacy in MS.

273 nt expansion of circulating Ara h 2-specific memory B cells that peaks at week 7.

274 mmune systems of infected hosts to recall of memory B cells that recognized the lateral patch, the pr

275 is conferred by allergen-specific long-lived memory B cells that replenish the IgE(+) PC compartment.

276 doses of vaccine, the majority of donors had memory B cells that secreted IgGs specific for H7 HA, wi

277 tem-directed bnAb, 3I14, isolated from human memory B cells, that utilizes a heavy chain encoded by t

278 are able to activate and expand Ag-specific memory B cells; these cultured cells are highly effectiv

279 an already primed immune system to diversify memory B cells to recognize closely related, but antigen

280 ic differences in the responses of naive and memory B-cells to antigen.

281 +)CD27(+) B cells in that they share typical memory B-cell transcription patterns with IgG(+) post-GC

282 Because 2.5% of switched memory B cells use IGHV4-34*01 and >43% of these have mu

283 However, the CD19(+)CD27(+) memory B cells utilize only the homeostatic pathway.

284 lescence, only IgG (and no IgA) RSV-specific memory B cells were detectable in peripheral blood.

285 HCV-specific class-switched memory B cells were detected in 3 out of 7 participants

286 revealed that frequencies of class-switched memory B cells were increased in the patients, whereas f

287 lly activated CD27(+) memory and nonswitched memory B cells were observed in patients with AD (P < .0

288 Almost all switched memory B cells were of donor origin.

289 uenza infection, in which virus-specific IgA memory B cells were readily recovered.

290 ed cytotoxicity and degranulation, levels of memory B cells were reduced, and serum IgG4 levels were

291 ivated homed to the lamina propria) and CD44 memory B cells, whereas PN-BBS assimilated chow levels.

292 s, we found that, in contrast with naive and memory B cells, which gathered antigen toward the synaps

293 hancing BCR signal strength permitted IgE(+) memory B cells-which essentially do not exist under norm

294 e and the severe reduction in class-switched memory B cells, while gathering longitudinal laboratory

295 tent infection within a subset of its host's memory B cells, while lytic EBV replication takes place

296 immunoglobulin heavy chains from circulating memory B cells with 2x250 paired-end sequencing on the I

297 were shown to harbor H-2K(d)-specific IgG(+) memory B cells with a post-germinal center phenotype (CD

298 s induced a relative decrease in circulating memory B cells with concomitant expansion of circulating

299 cursor, transitional T3, and PDL-2(+)CD80(+) memory B cells, with significantly elevated CD69 and CD8

300 rated via class-switch recombination in IgG1 memory B cells without additional somatic hypermutation.