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1 hyaluronic acid accumulation in the palatal mesenchyme.
2 l invasion into the surrounding adipose-rich mesenchyme.
3 ized cell behaviour intrinsically within the mesenchyme.
4 l transducer Smo in either pp endoderm or NC mesenchyme.
5 h endoderm and neighboring neural crest (NC) mesenchyme.
6 ron bone at the lateral edges of the ventral mesenchyme.
7 ries and inhibits ECM assembly in the tissue mesenchyme.
8 that invaginate and bud into the underlying mesenchyme.
9 master control gene expressed in pericloacal mesenchyme.
10 nd instructive cues from the surrounding gut mesenchyme.
11 proliferative expansion of the adjacent lung mesenchyme.
12 ributes to the inductive potential of dental mesenchyme.
13 f Wnt-induced epithelium into the underlying mesenchyme.
14 ral coloboma, and a deficiency of periocular mesenchyme.
15 g murine airway epithelium in the absence of mesenchyme.
16 lating the inductive potential of the dental mesenchyme.
17 ically within the second heart field-derived mesenchyme.
18 e dental epithelium and neural crest-derived mesenchyme.
19 naling between the epithelium and underlying mesenchyme.
20 regulating cell proliferation in the facial mesenchyme.
21 the primary cilia in the CNC-derived palatal mesenchyme.
22 regulation of BMP activity in the subaortic mesenchyme.
23 cription factor, in the undifferentiated cap mesenchyme.
24 isrupted specifically in the bovine limb bud mesenchyme.
25 letion in cell culture and developing kidney mesenchyme.
26 (Gdnf) expression domain in the surrounding mesenchyme.
27 tion of the ureteric bud and the metanephric mesenchyme.
28 des the betaA subunit of Activin, in the UGS mesenchyme.
29 cle originates from the ventral and tail bud mesenchyme.
30 ncreased SHH expression in the posterior leg mesenchyme.
31 xpression pattern in female VMP and prostate mesenchyme.
32 ete posterior domain of nascent hindlimb bud mesenchyme.
33 prevent premature differentiation of the cap mesenchyme.
34 sts and derives probably from submesothelial mesenchyme.
35 atenin signaling is disrupted in the palatal mesenchyme.
36 lations: the ureteric epithelium and the cap mesenchyme.
37 wnregulation of Msx1 expression in the tooth mesenchyme.
38 nic oral epithelium and neural-crest-derived mesenchyme.
39 irway tips and decreased Hoxb5 and VEGFR2 in mesenchyme.
40 by serial recombination with rat urogenital mesenchyme.
41 ion of a reporter gene in the posterior limb mesenchyme.
42 n in forebrain neuroectoderm and frontonasal mesenchyme.
43 tes nephron development from the metanephric mesenchyme.
44 h to coordinate growth and patterning in gut mesenchyme.
45 Dkk2, in the maxillary and mandibular tooth mesenchyme.
46 ding Dkk2 and Sfrp2, in the developing tooth mesenchyme.
47 f2c, Sox6, and Sp7 in the developing palatal mesenchyme.
48 d decreased cell proliferation in the distal mesenchyme.
49 antly upregulated in the Osr2 mutant palatal mesenchyme.
50 rea of proliferation of the neighboring root mesenchyme.
51 adhesion in the PS epithelia and underlying mesenchyme.
52 of the Shh signaling pathway in the palatal mesenchyme.
53 spatial and transcriptional map of the lung mesenchyme.
54 hrough sonic hedgehog (SHH) signaling to the mesenchyme.
55 comprised of smooth muscle and peri-urethral mesenchyme.
56 nactive state broadly across the distal limb mesenchyme.
57 0.5 murine epithelial progenitors and native mesenchyme.
58 3a and Sema3d genes in the embryonic palatal mesenchyme.
59 transition in cultured isolated metanephric mesenchyme.
60 stinct cellular identities within the dental mesenchyme.
61 mpaired protein glycosylation in the palatal mesenchyme.
63 rect Foxc1 target also expressed in the head mesenchyme, acts as a cerebellar radial glial mitogen an
65 al organ that develops from undifferentiated mesenchyme, although the mechanisms that regulate the de
66 n with enhancers active in the proximal limb mesenchyme and antagonizes the repressive function of TA
67 PDGFRalpha and PDGFRbeta in the craniofacial mesenchyme and demonstrate that the receptors form funct
68 29(K326X/+) embryos showed confluent palatal mesenchyme and epithelium at e18.5 ( n = 16), and no mic
69 lthough Fgfr3 and Fgfr4 are expressed in the mesenchyme and epithelium, inactivation in the mesenchym
71 ctive mechanical properties of the embryonic mesenchyme and establish engineering strategies for more
72 , despite its broad contribution to hindlimb mesenchyme and facial epithelium, the Isl1-beta-catenin
73 ve rise to Shh-expressing posterior hindlimb mesenchyme and Fgf8-expressing mandibular epithelium.
74 oles of YAP/TAZ in endodermal epithelium and mesenchyme and find that, although dispensable for gastr
75 ent stem cell within the adult hair follicle mesenchyme and has important implications toward restora
76 inactivated Gata4 in the septum transversum mesenchyme and its derivatives by using Cre/loxP technol
77 ideas about the contributions of mesodermal mesenchyme and neural crest to particular structures.
78 nations were constructed using avian hindgut mesenchyme and non-intestinal epithelium from the bursa
79 ription factor is highly expressed in dental mesenchyme and preodontoblasts, while in mature, secreto
81 al signaling among the ureteric tubules, cap mesenchyme and surrounding stromal mesenchyme to orchest
83 has demonstrated the striking ability of the mesenchyme and the stroma to instruct epithelial form an
84 f the GFP-positive, self-renewing progenitor mesenchyme and therefore restores normal renal developme
86 tion of this signal in the developing dental mesenchyme and whether adult dental pulp tissue maintain
87 e Wnt/beta-catenin/Bmp4 axis (in the stromal mesenchyme) and Bmp4/p63 signaling (in the epithelium) p
88 number upstream of Shh-dependent (posterior mesenchyme) and Shh-independent, cilium-based (anterior
89 endothelial cells to communicate with thymic mesenchyme, and for the differentiation of vascular-asso
90 cient in dissociated MM cells than in intact mesenchyme, and the nephrogenic competence of transduced
91 d Wnt signaling between dental epithelia and mesenchyme, and this cilia-dependent integration is requ
93 pansion and maturation of the epithelium and mesenchyme, as demonstrated by differentiated intestinal
95 lia are located in the dental epithelium and mesenchyme at early stages of tooth development and late
96 s, is widely expressed in the nascent tongue mesenchyme at the onset of tongue morphogenesis but its
97 ranscription factor II) in the Wolffian duct mesenchyme became intersex-possessing both female and ma
98 pt-villus architecture and a laminated human mesenchyme, both supported by mouse vasculature ingrowth
99 etected Shroom3 expression in the condensing mesenchyme, Bowman's capsule, and developing and mature
100 senchyme and epithelium, inactivation in the mesenchyme, but not the epithelium, recapitulated the de
102 al morphogenesis is prevented in the ventral mesenchyme by the concomitant induction of osteogenesis
103 and Tbx3 maintain proliferation of the lung mesenchyme by way of at least two molecular mechanisms:
104 nto ASM around airway stalks; flanking stalk mesenchyme can be induced to form an ASM niche by a late
106 sue-specific inactivation of Osr1 in the cap mesenchyme caused premature depletion of nephron progeni
108 nditional inactivation of Tak1 or Jun in cap mesenchyme causes identical phenotypes characterized by
109 icating that Jag1-Notch1 signaling restricts mesenchyme cell proliferation non-cell autonomously.
110 onversation between the skeletogenic primary mesenchyme cells (PMCs) and the overlying pattern-dictat
111 um carbonate skeleton is secreted by primary mesenchyme cells (PMCs) in response to largely unknown p
112 rupts the patterning and function of primary mesenchyme cells (PMCs), which form the embryonic skelet
113 ll over the embryo, including in the primary mesenchyme cells and in the surface epithelial cells.
114 signaling in UGS increases proliferation of mesenchyme cells and suppresses androgen-induced prolife
115 r (FGF) signaling in mouse embryonic palatal mesenchyme cells and that Srf neural crest conditional m
116 show that although cultured embryonic dental mesenchyme cells are unable to induce tooth formation, t
118 chick wing buds, we demonstrate that distal mesenchyme cells intrinsically time Hoxa13 expression, c
121 ut to investigate if the failure of cultured mesenchyme cells to form bioengineered teeth might be re
123 at4 influences signaling from stromal to cap mesenchyme cells to regulate their differentiation into
124 h E12.5 and E13.5 in the Osr2(RFP/-) palatal mesenchyme cells, in comparison with Osr2(RFP/+) litterm
125 specification of skeletogenic cells (primary mesenchyme cells, or PMCs) has recently been elucidated.
126 protein localization is polarized within cap mesenchyme cells, where it accumulates at the interface
127 s1 in mice leads to increased numbers of cap mesenchyme cells, which are abnormally arranged around t
128 d by support and stromal tissues formed from mesenchyme cells, which are not generally thought to for
133 l ectoderm boundary, we examined the cranial mesenchyme, composed of mixed neural crest and paraxial
136 the presence of these Vdr gene enhancers in mesenchyme-derived bone cells and to describe the epigen
137 Although FOXF1 is expressed in multiple mesenchyme-derived cell types, cellular origins and mole
138 r positive, which is consistent with both MD mesenchyme-derived cells and the purported importance of
139 s and mathematical simulations, we find that mesenchyme-derived GDF10 and GREM1 are major controllers
142 conditions and, with the inclusion of native mesenchyme, develop into pancreatoids expressing markers
144 ational change in the cytoskeletal system of mesenchyme dictates the maintenance and differentiation
145 e Erk2 deletion is restricted to the palatal mesenchyme, did not display cleft palate, suggesting tha
146 ombined with HIOs in vitro migrated into the mesenchyme, differentiated into neurons and glial cells
147 ocal interactions between the epithelium and mesenchyme, diverse integumentary organs form and underg
149 n of the Wnt target gene c-Myc from the lung mesenchyme during development does not affect proper epi
151 on of the distal endoderm and the underlying mesenchyme during lung branching morphogenesis, but litt
152 ned that Ar DNA methylation decreases in UGS mesenchyme during prostate bud formation in vivo and tha
153 resses generated by cells of embryonic tooth mesenchyme, either within cultured aggregates or in deve
154 ering the dorsoventral character of the limb mesenchyme elicits a change in the profile of propriocep
155 tion of polarity results in an epithelial-to-mesenchyme (EMT) transition and possible increased metas
157 ly promoted by COUP-TFII, which suppresses a mesenchyme-epithelium cross-talk responsible for Wolffia
160 at the developing mandibular molar tooth bud mesenchyme expresses significantly higher levels of Dkk2
161 later, cells in the leaflet/annulus junction mesenchyme expressing inactive NFATC1 (5.5-9 weeks) were
162 evelopmental stage 15 when osteochondrogenic mesenchyme forms condensates for each plastron bone at t
163 G mutations show a pre-induction metanephric mesenchyme gene expression pattern and are significantly
164 ium (NGE), and between GE and the underlying mesenchyme (GM) were enriched in multiple GO terms and K
165 f SHH signaling in either the endoderm or NC mesenchyme had direct and indirect effects on both cell
166 genesis-suppressing cell fate in the ventral mesenchyme has permitted turtles to develop their order-
169 mb, Isl1-lineages broadly contributed to the mesenchyme; however, deletion of beta-catenin in the Isl
170 idermis requires signals from the underlying mesenchyme; however, the specific pathways involved rema
171 noic acid synthesis are expressed in the UGS mesenchyme in a sex specific manner and addition of liga
172 n was significantly upregulated in the molar mesenchyme in Bmp4(f/f);Wnt1Cre embryos, which correlate
174 are associated with reduced proliferation of mesenchyme in developing nasal processes and adjacent ti
175 upregulated and expanded into the tooth bud mesenchyme in Inhba(-/-) embryos in comparison with wild
177 its conditional deletion from early limb bud mesenchyme in mice severely affects both initiation and
178 d throughout the neural crest-derived tongue mesenchyme in mouse, but not in chick, embryos during ea
179 bryos and is partially restored in the tooth mesenchyme in Msx1(-/-)Osr2(-/-) mutants in comparison w
181 unx2 expression is expanded in the tooth bud mesenchyme in Osr2(-/-) mutant mouse embryos and is part
183 (DEGs) were found between the epithelium and mesenchyme in the base of oral cavity as compared to the
184 within the primary cilia of the CNC-derived mesenchyme in the lip and palate region in mice and is a
185 essed in the mandibular than maxillary molar mesenchyme in wild-type embryos and that Dkk2 expression
186 t a detailed gene expression map of the head mesenchyme in X. laevis during early larval development,
187 tooth developmental inhibitors in the tooth mesenchyme, including Dkk2 and Osr2, and synergizes with
188 ccurred when Geminin was excised in paraxial mesenchyme, indicating a tissue autonomous requirement f
189 m, lens, and neural crest-derived periocular mesenchyme induced severe eye abnormalities with high pe
190 erning mechanisms divide the vertebrate head mesenchyme into a highly conserved set of skeletal precu
191 in II contractility drives the smooth dermal mesenchyme into a pattern of surface bumps that triggers
192 agination of epithelium into the surrounding mesenchyme is a critical step that marks the development
194 It is generally accepted that the inductive mesenchyme is capable of inducing the odontogenic commit
195 on of Inhba and Bmp4 in the developing tooth mesenchyme is independent of each other, Bmp4(ncko/ncko)
197 on of Wnt5a is observed in mutant pancreatic mesenchyme, leading to subsequent loss of expression of
198 ssion of beta-catenin within the metanephric mesenchyme leads to ectopic and disorganized branching m
199 ta-catenin overexpression in the metanephric mesenchyme leads to elevated levels of transcriptionally
200 ditional inactivation of Porcn in periocular mesenchyme led to defects in mid- and hindbrain and in c
201 nce cell interactions between epithelial and mesenchyme-like tissues coordinate liver bud formation a
204 hough expressed in the mouse posterior fossa mesenchyme, loss of Foxc1 non-autonomously induces a rap
206 nine kinase 11), in the fetal Mullerian duct mesenchyme (MDM), the caudal remnant of which is thought
207 attacking the host immune response through a mesenchyme-mediated immune control (MMIC) mechanism.
208 F-AA-treated primary mouse embryonic palatal mesenchyme (MEPM) lysates and analyzed the peptides by n
209 ecified in vegetal epithelium, transition to mesenchyme, migrate, and re-enter ectoderm, distributing
212 stin deposition, and hypercellularity of the mesenchyme occurred independently of airway branching de
213 DGFRbeta are coexpressed in the craniofacial mesenchyme of mid-gestation mouse embryos and that ablat
214 icular (AV) junction EPDCs contribute to the mesenchyme of the AV sulcus, the annulus fibrosus, and t
215 that FGF18, which is expressed in the distal mesenchyme of the limb bud, induces premature expression
216 zation showed that Dlx4 was expressed in the mesenchyme of the murine palatal shelves at E12.5, prior
219 liferation was reduced in the branchial arch mesenchyme of Yap and Taz CNC conditional knockout (CKO)
220 ied by significant upregulation, in the lung mesenchyme, of peroxisome proliferator-activated recepto
221 not affect Fgf10 expression in the adjacent mesenchyme or Fgfr2 expression in the epithelium, but ap
224 ed proliferation in the medial nasal process mesenchyme paralleled the domain of reduced Foxf2 and Gl
225 cal Wnt signaling, in the developing palatal mesenchyme, particularly in the posterior regions of the
227 er regeneration and axis formation, the pulp mesenchyme (Pp) which is derived from DP cells and nouri
228 steocalcin-Cre to transform undifferentiated mesenchyme, preosteoblasts and mature osteoblasts, respe
230 the acute phase of epithelial injury as the mesenchyme proliferates in response, but returns to base
231 ng subsequently restrains Bmp-mediated valve mesenchyme proliferation by sustaining Hbegf-EGF recepto
232 geting of Foxf2 by Shh signaling drives cNCC mesenchyme proliferation during upper lip morphogenesis,
233 Significantly, the negative regulator of mesenchyme proliferation, Hbegf, was markedly reduced in
234 dysmorphology was associated with increased mesenchyme proliferation, indicating that Jag1-Notch1 si
236 chondrocytes, osteoblasts, and craniofacial mesenchyme ( Prx1-cKO) would phenocopy skeletal and dent
237 nductive interactions between epithelium and mesenchyme regulate gut development, but the influence o
240 ated interactions between the epithelium and mesenchyme required for normal lung development can be d
242 elevation of beta-catenin in the metanephric mesenchyme results in cell-autonomous and non-cell-auton
243 We demonstrate that loss of Kif3a in dental mesenchyme results in loss of Hedgehog signaling and gai
245 R) and RNA sequencing on lung epithelium and mesenchyme retrieved by laser capture microdissection.
246 l partial inactivation of Fgfr2b in the lung mesenchyme reveal the involvement of both receptors in l
247 scopy within the zebrafish paraxial mesoderm mesenchyme reveals a physical association between Integr
248 Bmp signal reception in either epithelium or mesenchyme reveals that Bmp signaling in Hh-responsive m
252 esting that EphA4/EphA7 from the pericloacal mesenchyme signal via ephrin B2 to mediate ND insertion.
255 Here we identify that exosomes loaded with mesenchyme-specific mature microRNA contribute mobile ge
258 and EphA7, are specifically expressed in the mesenchyme surrounding the caudal ND and the cloaca, and
259 ion in nephrons, ureteric smooth muscle, and mesenchyme surrounding the lower urinary tract (via the
261 al FGF ligands and mediated through periotic mesenchyme that controls the number of sensory progenito
262 al plate coelomic epithelium gives rise to a mesenchyme that populates the pleuroperitoneal folds iso
263 ively, when recombined with fetal mouse lung mesenchyme, the cells recapitulated epithelial-mesenchym
265 k2 than the developing maxillary molar tooth mesenchyme, these data indicate that Bmp4 and activin si
266 cts to repress BMP activity in the subaortic mesenchyme through transcriptional inhibition of bmp4, a
267 depleting functional Bmp4 mRNAs in the tooth mesenchyme, through neural crest-specific gene inactivat
268 requires GDNF signaling from the surrounding mesenchyme to cells at the ureteric bud tips, via the Re
269 ion of the elastogenic machinery in the lung mesenchyme to control orderly formation of the elastin E
271 including Bmp4 and Fgf3, in the early tooth mesenchyme to drive tooth morphogenesis through the bud-
272 mary, exosomal transport of miR-133b-3p from mesenchyme to epithelium decreases DIP2B, which may func
274 h-threshold response genes in the underlying mesenchyme to form a signaling center called the "villus
276 ules, cap mesenchyme and surrounding stromal mesenchyme to orchestrate complex morphogenetic events.
277 , loaded into exosomes, was transported from mesenchyme to the salivary epithelium, which did not exp
278 paired apoptosis and failure of the anterior mesenchyme to undergo SOX9-dependent chondrogenesis, ins
279 through Bmp signalling from the interdigital mesenchyme, to regulate specification of joint progenito
280 F-beta-induced growth inhibition, epithelial-mesenchyme transition (EMT), and regulatory T cell (Treg
282 otein core of proteoglycans, from the dental mesenchyme using Osr2-Cre, which is also strongly expres
284 class II+, or CD11b+ immunocytes in the skin mesenchyme was increased, and essentially no subcutis de
285 In addition, ectopic FGFR activation in mesenchyme was sufficient to increase sensory progenitor
287 f the NF-kappaB pathway specifically in lung mesenchyme, we utilized the mesenchymal Twist2-Cre to dr
288 The impacts of altered signaling on the mesenchyme were assessed by implanted Wnt11- or Wnt3a-ex
289 subset analysis showed that VMP and adjacent mesenchyme were composed of distinct cell types and that
292 cells, IL-25 in epithelium and IL-13 in the mesenchyme were significantly reduced, but Tm burden was
293 r polarity within the early pre-chondrogenic mesenchyme, when skeletal shape is established, and prov
294 n of Sox9 persisted in the developing tongue mesenchyme where chondrogenesis is subsequently activate
295 g (Shh) is expressed in the distal posterior mesenchyme, where it acts as a mediator of anterior to p
296 ates the proliferative expansion of the lung mesenchyme, whereas inactivation of hedgehog signalling
298 mic retinoic acid (RA) landscapes in feather mesenchyme, which modulate GREM1 expression and epitheli
299 sion of morphogenetic genes in inductive UGS mesenchyme, which promotes proliferation and cytodiffere
300 ffinities intrinsically change in the distal mesenchyme, which we suggest results in a gradient of po
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