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1 blocking a direct route to embryonic cardiac mesoderm formation.
2 ing played an ancestral role in deuterostome mesoderm formation.
3 GSK-3 is also required for zebrafish dorsal mesoderm formation.
4 factor signaling during endoderm and ventral mesoderm formation.
5 pression of Xenopus Brachyury causes ectopic mesoderm formation.
6 , suggesting that ActRIB is not required for mesoderm formation.
7 nman gene, which is essential for the dorsal mesoderm formation.
8 of genes critical for the earliest events in mesoderm formation.
9 eveal a redundant function of oep and ntl in mesoderm formation.
10 ay upstream of Nodal signaling and posterior mesoderm formation.
11 gene, which is required for posterior (tail) mesoderm formation.
12 the prominent role of XRCC1 in endoderm and mesoderm formation.
13 o tail (ntl), which is essential for correct mesoderm formation.
14 which act to mediate different mechanisms of mesoderm formation.
15 eas ectopic expression of DeltaNp63 inhibits mesoderm formation.
16 re required in the YSL for endoderm and head mesoderm formation.
17 h factor-beta superfamily that induce dorsal mesoderm formation.
18 Wnt/beta-catenin signaling and required for mesoderm formation.
19 er and this function is essential for dorsal mesoderm formation.
20 1, Map4k4, and Bicc1 have essential roles in mesoderm formation.
21 1 and Foxc2 negatively regulate intermediate mesoderm formation.
22 hitherto been unclear, also plays a role in mesoderm formation.
23 f twist, a transcription factor required for mesoderm formation.
24 l (ntl) are together essential for posterior mesoderm formation.
25 posterior structure development and inhibits mesoderm formation.
26 activity of the Src and Laloo kinases during mesoderm formation.
27 s a gene crucial for proper gastrulation and mesoderm formation.
28 sses in the mouse embryo, beyond its role in mesoderm formation.
29 brain fates, without blocking ventrolateral mesoderm formation.
30 s by suppressing signals that promote dorsal mesoderm formation.
31 ogenitors without affecting primitive streak mesoderm formation.
32 embryo proper, Eomesodermin is essential for mesoderm formation.
33 ed to play an important part in endoderm and mesoderm formation.
34 endoderm morphology and severe disruption of mesoderm formation.
35 al VegT mRNA and have studied the effects on mesoderm formation.
36 scriptional effector of Nodal signals during mesoderm formation [17], but no mutations in the Fast-1
37 the one in which BMP4 was reported to drive mesoderm formation, also differentiate at least partiall
38 Thus, Smad7 acts as a potent inhibitor of mesoderm formation and also activates the default neural
39 ssues at the time of gastrulation for normal mesoderm formation and also suggest that subsequent Alk2
40 gene, T or Brachyury, which is required for mesoderm formation and axial elongation during embryogen
42 was used to evaluate TGF-beta involvement in mesoderm formation and cardiopoietic differentiation, wh
43 tch FGFR signal interpretation to coordinate mesoderm formation and cell movements during gastrulatio
44 ed anterior neural markers in the absence of mesoderm formation and DN-IGFR inhibited neural inductio
45 igate whether their function is required for mesoderm formation and gastrulation as implicated in Xen
47 rms that derriere plays an important role in mesoderm formation and it illustrates the complex regula
50 ting at a gastrulation-like stage, mediating mesoderm formation and patterning (two prerequisites for
51 eta- and Bmp-regulated processes involved in mesoderm formation and patterning are surprisingly unaff
55 body differentiation enhances both paraxial mesoderm formation and the myogenic potential of the cel
56 -mutant embryos to analyze the mechanisms of mesoderm formation and ventral specification in a teleos
57 , altered epiblast patterning, impairment of mesoderm formation, and embryonic lethality at embryonic
59 al pathway in which pannier promotes cardiac mesoderm formation, and pointed acts subsequently in thi
60 ubstantially different during trunk and tail mesoderm formation, and propose a genetic model that acc
61 ression of bagpipe (bap), and hence visceral mesoderm formation, and the promotion of somatic muscle
62 al to the early vertebrate embryo, including mesoderm formation, anterior patterning, and left-right
63 that the mechanisms responsible for paraxial mesoderm formation are largely conserved across vertebra
64 Src is enzymatically capable of stimulating mesoderm formation, as an activated Src construct both p
65 eal an essential early role for scleraxis in mesoderm formation, as well as a later role in formation
66 nr1, Xnr2, Xnr4 and derriere mRNA all rescue mesoderm formation, as well as the formation of blastopo
67 XActRIIB, a truncated mutant (tXALK4) blocks mesoderm formation both in vitro and in vivo; moreover,
70 to promote ventral cell invagination during mesoderm formation, but how the downstream genes regulat
71 the C2/C3 lineage of 32-cell embryos blocks mesoderm formation, but neural crest is lost only in the
72 nstrated the inhibition of Ras/AP-1-mediated mesoderm formation by dominant-negative mutants of the F
73 sted whether endogenous Brat is required for mesoderm formation by expressing a dominant-negative, tr
74 SNIP1 plays a role in regulating dorsomedial mesoderm formation by the TGF-beta family member nodal.
78 mozygous mutant NSD1 embryos, which initiate mesoderm formation, display a high incidence of apoptosi
85 t cell (M) is responsible for all nongonadal mesoderm formation during postembryonic development.
86 vents in vertebrate embryogenesis, including mesoderm formation, establishment of left-right asymmetr
88 been demonstrated that snail is critical for mesoderm formation, for CNS development, and for wing ce
90 morpholino oligonucleotides interferes with mesoderm formation in a concentration-dependent manner a
91 ) produced posteriorized embryos and induced mesoderm formation in animal cap explants, indicating th
93 essential roles in regulating ventrolateral mesoderm formation in conjunction with wnt8, and in patt
94 n, is required for heart as well as visceral mesoderm formation in Drosophila, and at least one of se
97 h necessary and sufficient to direct cardiac mesoderm formation in frog embryos and human embryonic s
98 erm-mesoderm interaction promoted precardiac mesoderm formation in mouse embryonic stem cells and inv
99 anscription factor Foxh1 as regulating FLK1+ mesoderm formation in mouse embryonic stem cells, which
100 This model contrasts with the models of mesoderm formation in other vertebrates as it suggests t
103 (SRF) is a transcription factor required for mesoderm formation in the developing mouse embryo that i
105 es the genomic targets of a key regulator of mesoderm formation in the early mouse embryo, thereby pr
107 tor tyrosine kinases play a critical role in mesoderm formation in the frog, Xenopus laevis, acting a
110 that QSulf1 inhibits FGF2- and FGF4-induced mesoderm formation in the Xenopus embryo and FGF-depende
111 target genes function to limit the extent of mesoderm formation in the Xenopus gastrula, and point to
112 t produce mesoderm-inducing signals and that mesoderm formation in these embryos occurred ectopically
113 Using this system, we were able to induce mesoderm formation in Xenopus animal-cap tissue and to d
114 ctivates a receptor tyrosine kinase, induces mesoderm formation in Xenopus embryos through activation
115 onal regulator Foxd3 is essential for dorsal mesoderm formation in zebrafish, and that this function
116 locus, display severe defects in midline and mesoderm formation including absence of most of the somi
117 gnalling pathways that regulate endoderm and mesoderm formation interact is crucial to understanding
119 chyury is considered to have a major role in mesoderm formation, it is possible that Wnts might play
120 es have also been proposed to participate in mesoderm formation, neural crest cell migration, carcino
121 mpetition may be responsible for the lack of mesoderm formation observed in such injected embryos.
122 ve for Nodal signaling, Foxd3 did not rescue mesoderm formation or axial development, indicating that
123 nces revealed that Slugh is not required for mesoderm formation or for neural crest generation, migra
125 Tbx6, each of which is critical for paraxial mesoderm formation, since absence of any one of these fa
126 hese observations and with a role for ntl in mesoderm formation, some somites form within the tail re
127 l gene is required for non-notochordal trunk mesoderm formation; spadetail mutant embryos have major
128 by repressing two inhibitors of cardiogenic mesoderm formation-Tcf3 and Foxa2-and activating inducer
129 rsal argue against a proposed role for sc in mesoderm formation that had seemed potentially relevant
130 ed in the mesoderm maintenance machinery and mesoderm formation through the synergistic action of the
131 mutant combinations that disrupt Chordin and mesoderm formation to reveal additional signals that con
132 rder to better characterize the evolution of mesoderm formation, we have examined the role of FGF sig
134 tion in the early Xenopus embryo potentiates mesoderm formation whereas ectopic expression of DeltaNp
135 ells skewed toward the Flk-1(+)PDGFRalpha(-) mesoderm formation, which generated hematopoietic and en
136 myogenesis selectively, acting subsequent to mesoderm formation yet before induction of Mesp1 and Mes
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