ライフサイエンスコーパス: mesothelial

1 pleural-based therapies to modulate pleural mesothelial activation and parenchymal fibrosis progress

2 We observed that macrophage-mesothelial adhesion is Arg-Gly-Asp (RGD) sensitive and

3 os-associated apoptosis and proliferation in mesothelial and alveolar epithelial cells and may be lin

4 socolon and retroperitoneum are separated by mesothelial and connective tissue layers.

5 data provide a molecular mechanism by which mesothelial and epithelial FGF9 directs lung development

6 uclei, cytoplasm, and extracellular space of mesothelial and inflammatory cells around asbestos depos

7 We demonstrate that WT1 is expressed by both mesothelial and mesenchymal cells in idiopathic pulmonar

8 signal-regulated kinase (ERK1/2) pathway in mesothelial and pulmonary epithelial cells in vitro, but

9 e divided into two distinct regions: the sub-mesothelial and sub-epithelial compartments, which proli

10 that were cocultured with Jagged-1 knockdown mesothelial and tumor feeder cells.

11 Here, we demonstrate that mesothelial- and epithelial-derived FGF9, mesenchymal Wn

12 n RTK with known oncogenic properties in non-mesothelial cancer types.

13 wth factor-beta1 (TGF-beta1) induces pleural mesothelial cell (PMC) transformation into myofibroblast

14 Furthermore, mesothelial cell and macrophage expression of VEGF-C inc

15 enesis and indicate that signals controlling mesothelial cell entry are organ specific.

16 We visualized WT1(+) mesothelial cell entry into the lung by live imaging and

17 wth gene, may encode a negative regulator of mesothelial cell growth.

18 SV40 may be related to the very high rate of mesothelial cell immortalization that is characteristica

19 ory effects of DLX4 on CD44 levels and tumor-mesothelial cell interactions were abrogated when IL-1be

20 gated the ability of DLX4 to stimulate tumor-mesothelial cell interactions.

21 etastasis, potentiating invasion through the mesothelial cell layer and colonization of the submesoth

22 its ability to recruit an entirely exogenous mesothelial cell layer during development.

23 The epicardium, a mesothelial cell layer enveloping the myocardium, is act

24 The epicardium is a mesothelial cell layer essential for vertebrate heart de

25 tant contribution of somatic mesoderm to the mesothelial cell layer of the PE.

26 ovarian cancer metastasis, clearance of the mesothelial cell layer, to examine the clearance ability

27 cin promoted intercalation of filopodia into mesothelial cell layers and cell invasion.

28 A human mesothelial cell line (LP9/TERT-1) and isolated human pl

29 documented by immunocytochemistry in a human mesothelial cell line (MET5A) exposed to various concent

30 AR5 as well as LP9 cells, a human peritoneal mesothelial cell line, were analyzed by flow cytometry f

31 imens (n = 5), and MPM and SV40-immortalized mesothelial cell lines (n = 5).

32 SV40 oncoprotein expression in murine mesothelial cell lines enhanced spontaneous and asbestos

33 Murine mesothelial cell lines lacking wild-type p53 due to a po

34 addition, stress-induced senescence in human mesothelial cell lines was impaired by SV40 oncoprotein

35 immortal cell lines (SV40-transformed human mesothelial cell lines, S-HML).

36 the invasion of tumor cell clusters into the mesothelial cell lining of peritoneal cavity organs; how

37 Activation of mesothelial cell LPA1 induced CTGF expression by inducin

38 BKV replicated faster than SV40 and caused mesothelial cell lysis, not cellular transformation.

39 cancer cell death during adhesion to normal mesothelial cell monolayers.

40 loss-of-function mice, we demonstrated that mesothelial cell movement into the lung requires the dir

41 ary vessels arise from a unique extracardiac mesothelial cell population, the proepicardium, which de

42 ic grafting and subsequent identification of mesothelial cell populations, we demonstrate that a diff

43 gates the role of dynamic O-GlcNAcylation of mesothelial cell proteins in cell survival during exposu

44 s of erionite, and examined the hallmarks of mesothelial cell transformation in vitro and in vivo.

45 Here, we demonstrate that asbestos-induced mesothelial cell transformation is linked to increases i

46 There was evidence of mesothelial cell transition to a mesenchymal phenotype w

47 The mesothelial cell VEGF production was significantly reduc

48 ally in the developing mesothelium reveals a mesothelial cell-autonomous role for Ezh2 in repression

49 ion in mesothelial cells, demonstrating that mesothelial cell-derived C-C chemokines play a biologica

50 e vertebrate heart originates from migratory mesothelial cells (epicardium) that give rise to coronar

51 ly, we reported that SV40 infection of human mesothelial cells (HM) causes aberrant methylation of th

52 SV40 infection of human mesothelial cells (HM) causes early cellular immortaliza

53 Asbestos is cytotoxic to human mesothelial cells (HM), which appears counterintuitive f

54 er mesothelial cells (SHM) and primary human mesothelial cells (HM).

55 s not induce transformation of primary human mesothelial cells (HM); instead, asbestos is very cytoto

56 1 production were measured in vitro in human mesothelial cells (HMC) in the presence or absence of me

57 Human peritoneal mesothelial cells (HPMCs), the main source of IL-6 and V

58 ffluents, peritoneal tissues, and peritoneal mesothelial cells (HPMCs).

59 ning vesicle transportation in human pleural mesothelial cells (HPMCs).

60 n the developing liver, lung, and intestine, mesothelial cells (MCs) differentiate into specific mese

61 Mesothelial cells (MCs) form a single epithelial layer a

62 Mesothelial cells (MCs) line the peritoneal cavity and h

63 onstrated that MesP1+ mesoderm gives rise to mesothelial cells (MCs), which differentiate into HSCs a

64 13), and primary peritoneal and immortalized mesothelial cells (MeT5A) by immunohistochemistry, qRT-P

65 rom this organism, adhered to primary murine mesothelial cells (MMCs) in vitro.

66 proliferation in this tissue, rabbit ovarian mesothelial cells (OMC) were transfected in vitro with a

67 n of interleukin (IL)-8 in activated pleural mesothelial cells (PMC) and the migration of PMNL across

68 investigate whether talc stimulates pleural mesothelial cells (PMC) to release C-X-C and/or C-C chem

69 t mesothelioma cells (MMC) or normal pleural mesothelial cells (PMC).

70 Results indicate pleural mesothelial cells (PMCs) express ICAM-1 in tuberculous p

71 ies using NIH 3T3 fibroblasts and peritoneal mesothelial cells (PMCs) showed that CTGF blockade suppr

72 this study we demonstrate that mouse pleural mesothelial cells (PMCs), when stimulated with BCG or IF

73 Pleural mesothelial cells (PMCs), which are derived from the mes

74 P-1) activity in both primary Syrian hamster mesothelial cells (SHM) and primary human mesothelial ce

75 in peritoneal macrophages (TLR2/4, C5aR) and mesothelial cells (TLR2, C5aR).

76 al steps of OvCa metastasis and suggest that mesothelial cells actively contribute to metastasis.

77 Mesothelial cells also produced chemokines in response t

78 Ectopic hTERT expression immortalized normal mesothelial cells and a premalignant, p16(INK4a)-negativ

79 Mesotheliomas are tumors arising from mesothelial cells and are associated with asbestos expos

80 SV40 did not lyse mesothelial cells and caused a high rate of transformati

81 lls associated with the basal lamina beneath mesothelial cells and expressing activated leukocyte cel

82 ulture containing primary human fibroblasts, mesothelial cells and extracellular matrix can be adapte

83 reased phosphorylation of Tyr-216 in pleural mesothelial cells and GSK-3beta mobilization from the cy

84 f innate immune mediators from primary mouse mesothelial cells and human monocytic MonoMac6 cells, an

85 rt their ability to colonize and multiply in mesothelial cells and in both resident and recruited leu

86 However, normal mesothelial cells and mesothelioma cells from Bap1(+/-)

87 Immortalized human mesothelial cells and primary mesothelial cells, culture

88 y resident macrophages and then amplified by mesothelial cells and probably other cells of the perito

89 data identify distinctive fates for injured mesothelial cells and submesothelial fibroblasts during

90 t isolates may retain properties of reactive mesothelial cells and suggests that targets in addition

91 Both production of LPA by peritoneal mesothelial cells and the chemotactic activity in the co

92 submesothelial cells is higher than that of mesothelial cells and transitional cells.

93 In conclusion, mesothelial cells are an important source of VEGF.

94 In tuberculous pleurisy pleural mesothelial cells are exposed to mycobacteria in the ple

95 Mesothelial cells are generally thought to be "bystander

96 Mesothelial cells are uniformly infected but not lysed b

97 on, this study identified O-GlcNAcylation in mesothelial cells as a potentially important molecular m

98 These results define mesothelial cells as microbial sensors through TLRs and

99 s to telomerase activity before the infected mesothelial cells become transformed and immortalized.

100 by this approach was abundant in normal rat mesothelial cells but not expressed in rat MM cell lines

101 We found that infection of human mesothelial cells by SV40 is very different from the sem

102 1, Tcf21) and Tbx18, can be induced in naive mesothelial cells by the liver bud, both in vitro and in

103 Indeed, knockdown of CD157 in Met-5A mesothelial cells changed their morphology and cytoskele

104 e, for the first time, that human peritoneal mesothelial cells constitutively produce bioactive lipid

105 We show here that human peritoneal mesothelial cells constitutively produce LPA, which acco

106 Pleural mesothelial cells contribute to pleural rind formation b

107 We show that SV40 infection of human mesothelial cells directly causes overexpression of Notc

108 ) three Ca(2+) shuttling pathways in primary mesothelial cells during Ca(2+) oscillations: Ca(2+) shu

109 Mesothelial cells exposed to asbestos or bleomycin for 9

110 Mesothelial cells expressed podoplanin and ALCAM.

111 lly devoid of a mesothelium but that serosal mesothelial cells expressing the Wilm's tumor protein (W

112 ll lines than they were in normal peritoneal mesothelial cells from surgical specimens, in organ cult

113 sion of ovarian cancer cells into peritoneal mesothelial cells has also been analyzed and shown to re

114 Here we show that malignant mesothelial cells have an elevated Notch signaling pathw

115 y assays for PLA(2) indicate that peritoneal mesothelial cells have strong constitutive PLA(2) activi

116 Treatment of mesothelial cells in culture with carboplatin resulted i

117 uption is repaired and replaced by surviving mesothelial cells in peritoneal injury, and not by subme

118 esive nanoparticles (BNPs) can interact with mesothelial cells in the abdominal cavity and significan

119 of transformation in infected primary human mesothelial cells in tissue culture, leading to the form

120 achment of ovarian tumor cells to peritoneal mesothelial cells in vitro and increases the numbers of

121 overexpression of ET-1 induced MMT in human mesothelial cells in vitro and promoted the early cellul

122 Blocking fibronectin production in primary mesothelial cells in vitro or in murine models, either g

123 roduction in pleural tissues in vivo, and by mesothelial cells in vitro.

124 TGF-beta increases the VEGF production by mesothelial cells in vivo and in vitro.

125 r genetic mapping of Wilms' tumor-1-positive mesothelial cells indicated that peritoneal membrane dis

126 Activation of LPA1 on mesothelial cells induced these cells to express connect

127 this activity was undetectable or minimal in mesothelial cells infected and/or transformed by SV40 ta

128 tos did not influence telomerase activity in mesothelial cells infected with SV40.

129 Phenotype conversion of mesothelial cells into myofibroblasts, the so-called mes

130 RK1/2 activation in pulmonary epithelial and mesothelial cells is unclear.

131 mas (MMs) are aggressive tumors derived from mesothelial cells lining the lungs, pericardium and peri

132 g through the mesothelium, a single layer of mesothelial cells lining the peritoneal cavity.

133 eads by implantation of tumor cells onto the mesothelial cells lining the peritoneal cavity.

134 Endogenous peritoneal macrophages and mesothelial cells lining the peritoneum contain MCP-1, w

135 Binding of mesothelin on normal mesothelial cells lining the pleura or peritoneum to the

136 es apoptosis in MMC without affecting normal mesothelial cells of the pleura.

137 Novel findings include the following: mesothelial cells of the serosa transduce Hedgehog signa

138 l ester "mixed isomers" (CCFSE) dye to label mesothelial cells on the surface of the embryonic lung.

139 single-chain urokinase-bound rabbit pleural mesothelial cells or lung fibroblasts with kinetics simi

140 Although primary cultures of mesothelial cells or submesothelial fibroblasts each exp

141 ggregation and increases in EGF-R protein in mesothelial cells phagocytizing long asbestos fibers wer

142 anation for the ability of SV40 to transform mesothelial cells preferentially and indicate that asbes

143 ese findings indicate that cancer-associated mesothelial cells promote colonization during the initia

144 Fas expression rendering transformed ovarian mesothelial cells resistant to apoptosis.

145 Upon exposure to bacterial products, mesothelial cells secrete chemokines, but the signaling

146 pic 3D cultures, we found that primary human mesothelial cells secrete fibronectin in the presence of

147 Together, our data provide evidence that mesothelial cells serve as a source of vascular smooth m

148 line (LP9/TERT-1) and isolated human pleural mesothelial cells showed rapid and protracted asbestos-i

149 A subset of mesothelial cells situated atop the immune aggregates wa

150 In contrast, areas of reactive mesothelial cells stained positively for these enzymes.

151 Conditioned medium from peritoneal mesothelial cells stimulate migration, adhesion, and inv

152 nd, VCAM-1, inhibits EMT of chick epicardial mesothelial cells stimulated by TGFbeta isoforms.

153 In vitro, pleural mesothelial cells stimulated with bacille Calmette-Gueri

154 ovarian tumor cells as well as in peritoneal mesothelial cells that are in direct contact with dissem

155 ember proto-oncogenes in lung epithelial and mesothelial cells that are linked to proliferation and c

156 ereby favoring survival and proliferation of mesothelial cells that have sustained DNA damage.

157 inflammasome, a component of macrophages or mesothelial cells that leads to production of chemotacti

158 Mesothelial cells that line the serous cavities and oute

159 RAC1/SMAD-dependent signaling pathway in the mesothelial cells that promotes a mesenchymal phenotype

160 s are up-regulated in asbestos-exposed human mesothelial cells through an epidermal growth factor rec

161 hese data demonstrate an intrinsic origin of mesothelial cells to a coelomic organ and provide a nove

162 Exposure of mesothelial cells to asbestos complemented SV40 mutants

163 Recent studies have proposed mesothelial cells to be an important source of myofibrob

164 hesize that SV40 oncoproteins will sensitize mesothelial cells to DNA damage induced by asbestos or c

165 ty of the conditioned medium from peritoneal mesothelial cells to ovarian cancer cells.

166 the unusual susceptibility of primary human mesothelial cells to SV40 carcinogenesis.

167 hese observations support a scenario whereby mesothelial cells undergo a series of chronic injury, in

168 eport that stimulation of primary peritoneal mesothelial cells via nucleotide-binding oligomerization

169 Yet, Nod1 stimulation of mesothelial cells via RICK enhanced chemokine secretion

170 uced inflammasome/inflammation activation in mesothelial cells was CREB dependent, further supporting

171 2, TLR4, TRIF, or inflammasome components in mesothelial cells was critical for the production of CXC

172 ng anti-ALCAM antibodies, submesothelial and mesothelial cells were isolated by FACS.

173 cer cell apoptosis during adhesion to normal mesothelial cells which line the peritoneum.

174 sbestos induces a fibroblastic transition of mesothelial cells with a gain of mesenchymal markers (vi

175 Finally, infection of mesothelial cells with Listeria monocytogenes induced pr

176 Stimulation of human peritoneal mesothelial cells with OSM induced phosphorylation of gp

177 h factor (EGF) is a potent mitogen for human mesothelial cells, and autophosphorylation of the EGF re

178 two epithelial cell types, keratinocytes and mesothelial cells, and determined the effect on prolifer

179 tracellular matrix components, human primary mesothelial cells, and full-thickness human peritoneum a

180 ressed by submesothelial fibroblasts but not mesothelial cells, attenuated the peritoneal fibrosis bu

181 induced telomerase activity in primary human mesothelial cells, but not in primary fibroblasts.

182 ms of interactions of pathogenic fibers with mesothelial cells, crucial signaling pathways, and genet

183 rtalized human mesothelial cells and primary mesothelial cells, cultured from human omentum or clinic

184 a induced MIP-1alpha and MCP-1 expression in mesothelial cells, demonstrating that mesothelial cell-d

185 also shown to efficiently rupture peritoneal mesothelial cells, exposing the submesothelial collagen

186 BKV and SV40 infected mesothelial cells, expressed viral oncoproteins, and cau

187 on of Wilms tumor 1 (WT1), a known marker of mesothelial cells, in various cell types in normal and f

188 ormal tissues, mesothelin is present only on mesothelial cells, it represents a good target for antib

189 itol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, bu

190 le for this vascular defect was the yolk sac mesothelial cells, not the cardiomyocytes or the VSMC.

191 podoplanin was also expressed by peritoneal mesothelial cells, osteocytes, glandular myoepithelial c

192 In cultured mesothelial cells, TGF-beta1 upregulated the expression

193 We observed that, in primary mesothelial cells, the plasmalemmal Ca(2+) influx played

194 /apyrimidinic (AP)-endonuclease, in isolated mesothelial cells, the progenitor cells of malignant mes

195 because its normal expression is limited to mesothelial cells, which are dispensable.

196 he direct interaction of the OvCa cells with mesothelial cells, which cover the surface of the omentu

197 nment of chronic IL-1beta signaling in human mesothelial cells, which may promote mesothelial to fibr

198 entified in the allantois: an outer layer of mesothelial cells, whose distal portion will become tran

199 lite exposures have similar effects on human mesothelial cells.

200 vide a novel mechanism for the generation of mesothelial cells.

201 n implicated previously in transformation of mesothelial cells.

202 PRRs) in bone marrow-derived macrophages and mesothelial cells.

203 elioma tumor cells in situ but not by normal mesothelial cells.

204 ted in asbestos-induced oncogenesis of human mesothelial cells.

205 in MM cell lines compared with non-malignant mesothelial cells.

206 signaling pathway compared with normal human mesothelial cells.

207 f neutrophils via IL-1R/MyD88 on neighboring mesothelial cells.

208 tumor 1 gene (Wt1) is expressed only in the mesothelial cells.

209 -6 from macrophages but robust production in mesothelial cells.

210 assayed for in vitro cytotoxicity to murine mesothelial cells.

211 ar matrix proteins, as well as to peritoneal mesothelial cells.

212 of chemokine and antimicrobial responses in mesothelial cells.

213 ne marrow derived macrophages, as well as by mesothelial cells.

214 stimulated by angiogenic factors produced by mesothelial cells.

215 red chick embryonic and rat adult epicardial mesothelial cells.

216 lly expressed in MM cells compared to normal mesothelial cells.

217 in MM cells but had minimal effect on normal mesothelial cells.

218 We found that JCV did not infect human mesothelial cells.

219 l of a cell line derived from rat epicardial mesothelial cells.

220 required for the growth of SV40-transformed mesothelial cells.

221 ristically associated with SV40 infection of mesothelial cells.

222 xpression was restricted to human peritoneal mesothelial cells.

223 ers and is critical to the transformation of mesothelial cells.

224 rease in VEGF production from murine pleural mesothelial cells.

225 ely 40-fold higher levels of hDio2 mRNA than mesothelial cells.

226 orphologies and function compared to control mesothelial cells.

227 g the adhesion of ovarian carcinoma cells to mesothelial cells.

228 interaction of ovarian carcinoma cells with mesothelial cells.

229 its limited expression in normal peritoneal mesothelial cells.

230 5) in a dose-dependent manner in rat pleural mesothelial cells.

231 expression and TGF-beta1 expression in human mesothelial cells.

232 FA mRNA (P < 0.05) and protein (P < 0.05) in mesothelial cells.

233 sed concentrations of ID1 mRNA (P < 0.05) in mesothelial cells.

234 he O-GlcNAc signal primarily originates from mesothelial cells.

235 ion in normal human tissues is restricted to mesothelial cells.

236 ntum, which are covered by a single layer of mesothelial cells.

237 on of IL-1beta and IL-18 production in human mesothelial cells.

238 al effects and transforming actions in human mesothelial cells.

239 Acquisition of Ncad by Ecad+ cells increased mesothelial clearance activity but was not sufficient to

240 al-to-mesenchymal transition (EMT), promoted mesothelial clearance in cell lines with weak activity,

241 scription factors TWIST1 and ZEB1 attenuated mesothelial clearance in ovarian cancer cell lines with

242 tion is maintained in SV40-transformed human mesothelial clones and in SV40-positive mesotheliomas an

243 ish that regeneration of the epicardium, the mesothelial covering of the heart, is mediated by two ph

244 Mesothelial (CRL-9444 = MC) and MM (CRL-2081 = MM-1, CRL

245 nate while the long-studied cardiac model of mesothelial development may be the outlier.

246 Historically, analyses of mesothelial differentiation have focused on the heart wh

247 The mesothelial epicardium lost epithelial gene expression a

248 cancer cells exhibited increased adhesion to mesothelial explants excised from mice modeling diet-ind

249 Mesothelial FGF9 and mesenchymal WNT2A are principally r

250 Mesothelial Fibroblast Growth Factor 9 (Fgf9) has been d

251 edgehog signaling was not required for fetal mesothelial heart entry.

252 ated nuclear CREB1 as compared with reactive mesothelial hyperplasias and normal lung tissue.

253 se MCAs with peritoneal mesothelium disrupts mesothelial integrity, exposing the submesothelial colla

254 c adhesion molecule regulation of macrophage-mesothelial interactions.

255 ons in the regulation of ovarian cancer cell mesothelial invasion and metastatic progression and offe

256 Using a cell culture model system of mesothelial invasion, highly tumorigenic SKOV-3 and ES-2

257 Surprisingly, nonmalignant human mesothelial isolates expressed both NOS2 and COX2 in vit

258 correlates with the presence of an overlying mesothelial layer, which, as in vivo, expresses Fibrobla

259 R3(-/-) mice did not develop fibrosis of the mesothelial layer.

260 Where apposed to retroperitoneum, 2 mesothelial layers separated mesocolon and underlying re

261 show that cells originating from the Wt1(+) mesothelial lineage, which includes epicardial cells, di

262 with 9 mesothelioma cell lines and 3 normal mesothelial lines.

263 atments stimulate macrophage adhesion to the mesothelial lining of the peritoneal cavity.

264 spleen, an organ that originates within the mesothelial lining of the stomach.

265 bute to pleural rind formation by undergoing mesothelial mesenchymal transition (MesoMT), whereby the

266 notably upregulated during TGF-beta induced mesothelial-mesenchymal transition (MesoMT).

267 These results indicate that MCs undergo mesothelial-mesenchymal transition and participate in li

268 m the mesothelium (the future pleura) to sub-mesothelial mesenchyme through both FGF receptor (FGFR)

269 more efficient in transmigration through the mesothelial monolayer compared with poorly tumorigenic O

270 monitored for their ability to adhere to the mesothelial monolayer in the presence of potential inhib

271 neum and induce retraction of the peritoneal mesothelial monolayer prior to invasion of the collagen-

272 ent and extravasation across endothelial and mesothelial monolayers at sites of inflammation.

273 ibit, transmigration of SKOV-3 cells through mesothelial monolayers.

274 omous motion by subtracting the tissue-level mesothelial motion from the total endothelial cell displ

275 era model of gut morphogenesis reveals these mesothelial progenitors are broadly distributed througho

276 In this newly discovered model, mesothelial progenitors are intrinsic to organs of the d

277 Recent studies have shown that mesothelial progenitors contribute to mesenchymal lineag

278 lineage-tracing studies, we demonstrate that mesothelial progenitors of the intestine are intrinsic t

279 ction assays in organ cultures, and targeted mesothelial-restricted hedgehog loss-of-function mice, w

280 and AP-1 DNA binding activity in rat pleural mesothelial (RPM) cells, a target cell of asbestos-induc

281 sis (Affymetrix array) of normal rat pleural mesothelial (RPM) cells, RPM cells exposed to crocidolit

282 lines in comparison to isolated rat pleural mesothelial (RPM) cells.

283 ng after confirming that Cre recombinase was mesothelial specific and faithfully recapitulated endoge

284 In response to cardiac damage, a mesothelial tissue layer enveloping the heart called the

285 ular cell motility as well as the underlying mesothelial tissue motion.

286 ere significantly downregulated in malignant mesothelial tissues and malignant pleural mesothelioma (

287 ssion levels to classify benign vs malignant mesothelial tissues and the differences between pemetrex

288 ssues but were not detectable in nonreactive mesothelial tissues from the same individuals.

289 ferentially expressed in benign or malignant mesothelial tissues.

290 n human mesothelial cells, which may promote mesothelial to fibroblastic transition (MFT) in an NLRP3

291 lso revealed the process of asbestos-induced mesothelial to fibroblastic transition and its ameliorat

292 e the first to suggest that asbestos induces mesothelial to fibroblastic transition in an inflammasom

293 ild-type (WT) mice showed enhanced fibrosis, mesothelial to mesenchymal transition, IL-17 production,

294 ial cells into myofibroblasts, the so-called mesothelial-to-mesenchymal transition (MMT), significant

295 ted the PMC phenotype and showed evidence of mesothelial-to-mesenchymal transition (MMT), with a redu

296 ation and myofibroblast differentiation, PMC mesothelial-to-mesenchymal transition, and VEGF-A produc

297 57BL/6 mice with fibrosis, angiogenesis, and mesothelial-to-mesenchymal transition.

298 Examination of mesothelial ultrastructure revealed a substantial increa

299 tes to and envelops the myocardium supplying mesothelial, vascular and stromal cell lineages.

300 The effects of carboplatin on mesothelial VCAM-1 expression were determined in culture