ライフサイエンスコーパス: metabolic enzyme

1 s both the activity and stability of a major metabolic enzyme.

2 pS) is a universally conserved and essential metabolic enzyme.

3 f microbial physiology via manipulation of a metabolic enzyme.

4 for additional modulators of this important metabolic enzyme.

5 ponse, and glucokinase (Gck), encoding a key metabolic enzyme.

6 e resulted from the incorporation of primary metabolic enzymes.

7 criptional activation and phosphorylation of metabolic enzymes.

8 -phosphate) is an essential cofactor of many metabolic enzymes.

9 l mRNA expression levels of arachidonic acid metabolic enzymes.

10 enough to damage a growing list of essential metabolic enzymes.

11 (100-fold) up-regulation in dimethyl sulfide metabolic enzymes.

12 ing PAF levels through modulation of the PAF metabolic enzymes.

13 de novo with targeted mutations in critical metabolic enzymes.

14 to physically or functionally interact with metabolic enzymes.

15 ns, elastase, lysozyme, myeloperoxidase, and metabolic enzymes.

16 press all of the known endocannabinoid (eCB) metabolic enzymes.

17 he cytochrome P450 (cyt P450) superfamily of metabolic enzymes.

18 r (Moco), which serves as a redox center for metabolic enzymes.

19 ng patient response to therapies that target metabolic enzymes.

20 RNA synthetases) and moderate preference for metabolic enzymes.

21 trient needed as a cofactor for many central metabolic enzymes.

22 sma proteins, biotransformation enzymes, and metabolic enzymes.

23 nnels, apoptotic proteins, transporters, and metabolic enzymes.

24 ns, including ROS1 and ALK, as well as novel metabolic enzymes.

25 duplication and divergence of genes encoding metabolic enzymes.

26 ifunctional and rapidly evolving specialized metabolic enzymes.

27 ceptors (CB(1), CB(2), and TRPV1), and their metabolic enzymes.

28 y oncogene signaling and by dysregulation of metabolic enzymes.

29 resistance mechanisms that inhibit essential metabolic enzymes.

30 tance, often sharing a pedigree with primary metabolic enzymes.

31 st of a protein shell encapsulating specific metabolic enzymes.

32 te the levels of a variety of mRNAs encoding metabolic enzymes.

33 between the ArrA and AoxB clades of arsenic metabolic enzymes.

34 s ranging from transcriptional regulators to metabolic enzymes.

35 function by modulating the expression of key metabolic enzymes.

36 to understand the emerging biology of these metabolic enzymes.

37 biotic chemistry and the nature of the first metabolic enzymes.

38 acting as a rhythmic acetyl-transferase for metabolic enzymes.

39 d C-termini and by shielding components from metabolic enzymes.

40 e limited by the cell's capacity to maintain metabolic enzymes.

41 taenoic acid (EPA) using the same downstream metabolic enzymes.

42 imal polyanionic surfaces on a set of common metabolic enzymes.

43 interactions for genes of key regulatory and metabolic enzymes.

44 l of the 5- phosphate of the guide strand by metabolic enzymes.

45 electrophoresis to characterize nucleic acid metabolic enzymes.

46 red by altered abundance and activity of the metabolic enzymes.

47 cerevisiae purged of its endogenous glycogen-metabolic enzymes.

48 olecules, signaling proteins and a subset of metabolic enzymes.

49 Here we show that the metabolic enzyme acetyl-CoA synthetase 2 (ACSS2) directl

50 The central metabolic enzyme acetyl-CoA synthetase is regulated in b

51 motaxis histidine kinase CheAY2, the central metabolic enzyme aconitase (AcnB) and the detoxifying en

52 e we compare messenger RNA profiles of 1,454 metabolic enzymes across 1,981 tumours spanning 19 cance

53 ism thermogenic performance with measures of metabolic enzyme activities and genomic transcriptional

54 Our results revealed similar metabolic enzyme activities and metabolic clearance rate

55 te sensing coupled to feedback regulation of metabolic enzyme activity or expression.

56 ple exposure group (7.5%) indicated elevated metabolic enzyme activity, likely through the aryl hydro

57 When the challenge is the loss of a metabolic enzyme, adaptive responses can also shed signi

58 ency, but rather to dysfunction in the lipid metabolic enzyme AGMO, which is expressed in the epiderm

59 We show here that the metabolic enzyme alkylglyceronephosphate synthase (AGPS)

60 termination of the enzymatic activity of key metabolic enzymes allowed us to shed some light on the b

61 tracing biocatalytic mechanisms operating in metabolic enzymes along a phylogenetic timeline of the f

62 Other metabolic enzymes also assemble into filaments at low pH

63 acute effects via direct phosphorylation of metabolic enzymes, AMPK has longer-term effects by regul

64 chia coli protein BirA to function as both a metabolic enzyme and a transcription repressor relies on

65 insight into the genetic regulation of a key metabolic enzyme and add to our understanding of the div

66 that introduces a methyl modification into a metabolic enzyme and whose activity can be modulated by

67 ell-specific transcriptional analysis of ABA metabolic enzymes and ABA-responsive promoters, have all

68 Acetyl-CoA carboxylases (ACCs) are crucial metabolic enzymes and are attractive targets for drug di

69 processes-expression of specific isoforms of metabolic enzymes and autophagy-have been shown to be cr

70 ograde transport of cytoskeleton components, metabolic enzymes and axonal regeneration enhancers, was

71 ntributors to modified kinetic parameters of metabolic enzymes and candidates for further study.

72 RNAs result in a switch in the expression of metabolic enzymes and cause the acquisition of glucose-i

73 ria responsible for deacetylation of several metabolic enzymes and components of oxidative phosphoryl

74 semble synthetic transcription factors using metabolic enzymes and construct four different sensors t

75 rious effect of 2-aminoacrylate generated by metabolic enzymes and emphasizes the need for RidA to qu

76 e regulation of quorum sensing and secondary metabolic enzymes and encodes new pteridine metabolites

77 Acetyl-CoA carboxylases (ACCs) are crucial metabolic enzymes and have been targeted for drug develo

78 activated a focused gene network enriched in metabolic enzymes and implantation factors.

79 rx provides reducing equivalents for central metabolic enzymes and is implicated in redox regulation

80 , which transactivates target genes encoding metabolic enzymes and membrane transporters.

81 ow that oncogenes directly regulate critical metabolic enzymes and metabolic signaling pathways.

82 ell subsets, describe the emerging roles for metabolic enzymes and metabolites in the control of immu

83 erial proteins, such as glycolytic and other metabolic enzymes and molecular chaperones, and the role

84 ell known as a cofactor for numerous central metabolic enzymes and more recently for playing a role i

85 ples that illustrate the regulation of plant metabolic enzymes and pathways by PTMs and their cross t

86 ion of a large network of cytoprotective and metabolic enzymes and proteins.

87 egulates mitochondrial function by targeting metabolic enzymes and proteins.

88 signaling to 144 proteins, among which were metabolic enzymes and regulators.

89 tumour suppression, few connections between metabolic enzymes and senescence have been established.

90 Their acyl-CoA products regulate metabolic enzymes and signaling pathways, become oxidize

91 e the associations between the expression of metabolic enzymes and the levels of the metabolites part

92 s showed that HBc promoted the expression of metabolic enzymes and the secretion of metabolites in HC

93 late in evolution, at a time when primordial metabolic enzymes and translation machinery were already

94 We profiled an additional set of relevant metabolic enzymes and transporters, including Crc target

95 rofile by restoring the level of fatty acids metabolic enzymes and use.

96 e range are characteristic of a well-evolved metabolic enzyme, and as such, E. coli GmhB is set apart

97 In this new array, films of DNA, metabolic enzymes, and an ECL metallopolymer or complex

98 nt levels: by modulating the activity of key metabolic enzymes, and by massive transcriptional reprog

99 target not only GPCRs but also transporters, metabolic enzymes, and chaperones.

100 mitting ruthenium metallopolymer, microsomal metabolic enzymes, and DNA to detect potential genotoxic

101 bundance changes were validated for numerous metabolic enzymes, and highlight the increased carbon an

102 affects the localization and activity of key metabolic enzymes, and it may work antagonistically or c

103 mitochondrial respiratory chain proteins and metabolic enzymes, and knockdown of ClpP in leukemic cel

104 A theme is emerging wherein nutrients, metabolic enzymes, and metabolites can act as an extensi

105 al and altering expression of neuropeptides, metabolic enzymes, and other non-neural genes.

106 ex panel of 15 other metabolites, associated metabolic enzymes, and phosphoproteins, the resultant da

107 fic predicted responses to the inhibition of metabolic enzymes, and successfully inferred the prognos

108 g., the transcription-translation machinery, metabolic enzymes, and the replisome.

109 Some existing chemotherapies target metabolic enzymes, and there is a resurgent interest in

110 side the cell, and the expression of several metabolic enzymes are altered by acid-base status in par

111 Here, we report that the S1P receptors and metabolic enzymes are conserved in the genome of zebrafi

112 It is anticipated that understanding which metabolic enzymes are particularly critical for tumor ce

113 Metabolic enzymes are presumed regulators of this glycol

114 function not only by regulating activity of metabolic enzymes, as previously reported, but also by r

115 Numerous metabolic enzymes assemble into filamentous structures,

116 onal enzymes between Archaea and Eukarya and metabolic enzymes between Bacteria and Eukarya.

117 Specialized metabolic enzymes biosynthesize chemicals of ecological

118 These include several metabolic enzymes but also a small number of proteins in

119 level p73 does not directly regulate serine metabolic enzymes, but transcriptionally controls a key

120 ATP, polyphosphates such as DNA and RNA, and metabolic enzymes, but whether it plays a part in intrac

121 metabolic processes, this study shows that a metabolic enzyme can act as a pattern recognition recept

122 informative associations between kinases and metabolic enzymes capable of predicting metabolic change

123 Aldehyde oxidase (AOX) is a metabolic enzyme catalyzing the oxidation of aldehyde an

124 wly identified alterations in genes encoding metabolic enzymes, chromatin remodelers and a high propo

125 dynamically regulates its approximately 100 metabolic enzyme-coding gene targets.

126 hat TrmB functions alone to regulate central metabolic enzyme-coding genes but cooperates with variou

127 ctivation of Mtb's isocitrate lyases (ICLs), metabolic enzymes commonly assumed to be involved in rep

128 ions, they are good systems for studying how metabolic enzymes communicate via substrate channeling.

129 ipA is known to modify the E2 subunit of the metabolic enzyme complex pyruvate dehydrogenase (E2-PDH)

130 med SESAME (Serine-responsive SAM-containing Metabolic Enzyme complex), which contains serine metabol

131 yme A, which is synthesized using lipoylated metabolic enzyme complexes.

132 C specimens have similar alterations in atRA metabolic enzymes, consistent with reduced colonic atRA.

133 e lymphoid cells (ILC2), but whether certain metabolic enzymes control disease outcome has not been a

134 ctivity between mouse and primate carotenoid metabolic enzymes could account for this species-specifi

135 accharomyces cerevisiae was one of the first metabolic enzymes described as a multifunctional protein

136 Using the metabolic enzyme dihydrofolate reductase as a model syst

137 eneral mechanism to inactivate and store key metabolic enzymes during a state of advanced cellular st

138 of proteinaceous organelles that consist of metabolic enzymes encapsulated within a protein shell.

139 MCPs consist of metabolic enzymes encased within a protein shell that pr

140 Overall, MCPs consist of metabolic enzymes encased within a protein shell, and th

141 We identified an unexpected role for the metabolic enzymes enolase and aldo-keto reductase as pos

142 Choking cancer via inhibition of metabolic enzymes essential for tumor but dispensable in

143 Genes encoding metabolic enzymes exhibited expression in metacyclics wi

144 t has been shown that many of these cellular metabolic enzymes exist in sequential and proximal organ

145 etabolic phenotype or maladaptive changes in metabolic enzyme expression and regulation in the respon

146 sults suggest that the parameters regulating metabolic enzyme expression are optimized by evolution,

147 No toxicity was seen regarding metabolic enzyme expression, glutathione, or histopathol

148 ed cardiac hypertrophy and fibrosis, altered metabolic enzyme expression, increased cardiac transcrip

149 pression, including glutaminase (GLS), a key metabolic enzyme for tumour proliferation.

150 arboxylesterases were identified as the main metabolic enzymes for hydroxamic acids.

151 ndrial lipids reach inner membrane-localized metabolic enzymes for phosphatidylethanolamine synthesis

152 study identifies creatine kinases (CKs), key metabolic enzymes for rapid ATP generation via the phosp

153 ded to include a fully representative set of metabolic enzymes from human and rat liver microsomes, h

154 ucosal sites through mechanisms dependent on metabolic enzyme function.

155 ssays, we discovered that a diverse range of metabolic enzymes function in heterochromatin regulation

156 m, which includes inhibiting key glutathione metabolic enzymes (GCLC and GPX1), as well as direct dep

157 n key transcription factors and their target metabolic enzyme genes can explain the decreases in asso

158 nema pallidum, is compact and devoid of many metabolic enzyme genes.

159 -small cell lung cancer TICs overexpress the metabolic enzyme glycine decarboxylase, which leads to i

160 Fumarate hydratases (FHs) are essential metabolic enzymes grouped into two classes.

161 Although mutations in metabolic enzymes hardwire metabolism to tumourigenesis,

162 r-associated mutations in genes encoding key metabolic enzymes has provided a direct link between alt

163 The recent discovery of mutations in metabolic enzymes has rekindled interest in harnessing t

164 Thus, many metabolic enzymes have become targets for new cancer the

165 In particular, the catalytic activities of metabolic enzymes have been shown to be regulated by Lys

166 tional modification that targets a number of metabolic enzymes; however, the mechanisms and downstrea

167 ons in the X-linked gene encoding the purine metabolic enzyme, hypoxanthine guanine phosphoribosyl tr

168 ations of the isocitrate dehydrogenase (IDH) metabolic enzymes IDH1 and IDH2 have been found to be fr

169 rates that protein acetylation can stimulate metabolic enzymes, (ii) provides biochemical evidence th

170 MTHFD2 is the most differentially expressed metabolic enzyme in cancer versus normal cells.

171 oncept that LAL in hepatocytes is a critical metabolic enzyme in controlling neutral lipid metabolism

172 lts support a concept that LAL is a critical metabolic enzyme in lung epithelial cells that regulates

173 Based on homozygous deletions affecting metabolic enzymes in 16 TCGA cancer studies and 972 canc

174 tic protein scaffolds that spatially recruit metabolic enzymes in a designable manner.

175 s and ROS level, plus down-regulation of Hcy metabolic enzymes in aortae from Ang II-infused rats wer

176 Sequential metabolic enzymes in glucose metabolism have long been h

177 The role of lipid metabolic enzymes in Golgi membrane remodeling is a subj

178 hotspots in the IDH1 and IDH2 genes encoding metabolic enzymes in intrahepatic cholangiocarcinomas.

179 The differential expression of metabolic enzymes in noninvasive CL1-0 cells and invasiv

180 lism and a 1.5-fold increase in carbohydrate metabolic enzymes in PoplarCyc.

181 release, suggesting a limited role for these metabolic enzymes in rapid H(2)O(2) production in the st

182 oordinated through reversible acetylation of metabolic enzymes in response to nutrient availability.

183 strating a functional collaboration of these metabolic enzymes in response to oxidative stress.

184 The ability to strategically inhibit key metabolic enzymes in the purine pathway unexpectedly byp

185 riptional upregulation and repression of key metabolic enzymes in this pathway.

186 lity of the genes encoding putative c-di-GMP metabolic enzymes in Yersinia pestis.

187 where it regulates the acetylation levels of metabolic enzymes, including acetyl coenzyme A synthetas

188 In addition, RNAs encoding multiple metabolic enzymes, including enzymes sponsoring glycolys

189 and their metabolism is mediated by several metabolic enzymes, including fatty acid amide hydrolase

190 terica Pat (SePat) can acetylate a number of metabolic enzymes, including GAPDH, but we were unable t

191 YAP/TAZ activation modulated metabolic enzymes, including glutaminase (GLS1), to coor

192 Mutations in metabolic enzymes, including isocitrate dehydrogenase 1

193 This was in spite of COM1 lacking several metabolic enzymes, including nonphosphorylating glyceral

194 requires precise, coordinated action of DNA metabolic enzymes, including proteins responsible for DN

195 ion loops that control the expression of key metabolic enzymes, including the BR-inactivating enzymes

196 diated DNA repair, suggesting that targeting metabolic enzymes increases cancer cell susceptibility t

197 e, and nuclear factor-kappaB, as well as the metabolic enzyme, indoleamine-2,3-dioxygenase, which bre

198 r findings suggest that the primary cause of metabolic enzyme inhibition is not the evolution of regu

199 osis knockouts to predict the impact of both metabolic enzyme inhibitors and metabolic pathways explo

200 g the relevance and utility of incorporating metabolic enzymes into in vitro bioassays.

201 phoserine phosphatase (PSP), a key essential metabolic enzyme involved in conversion of O-phospho-l-s

202 te:ferredoxin oxidoreductase (PFOR), a major metabolic enzyme involved in energy generation through o

203 mes, proteases, G-protein-coupled receptors, metabolic enzymes, ion transporters, and proteins of unk

204 teomic evidence suggests that acetylation of metabolic enzymes is a prevalent post-translational modi

205 ntification of heterozygous mutations in the metabolic enzyme isocitrate dehydrogenase (IDH) in subse

206 Mutations in the metabolic enzymes isocitrate dehydrogenase 1 (IDH1) and

207 Mutations in the metabolic enzymes isocitrate dehydrogenase-1 (IDH1) and

208 increased glycolysis, changes in the use of metabolic enzyme isoforms, and increased secretion of la

209 The tryptophan metabolic enzyme kynureninase (KYNU) is mimicked by a po

210 fically, genetic manipulation of a secondary metabolic enzyme led to altered free-running rhythms.

211 egulatory responses, 3) quantified glutamate metabolic enzyme levels in the VMH, 4) examined astrocyt

212 monia and nitrite transport proteins and key metabolic enzymes mainly in the bottom large granules fa

213 III secretion effector protein (SteA), and a metabolic enzyme (malate dehydrogenase), and demonstrate

214 Here we show that mice lacking the monoamine metabolic enzymes MAO A and MAO B (MAO AB-deficient mice

215 nterparts in primary metabolism, specialized metabolic enzymes may be more tolerant to mutations norm

216 tection on the protein synthesis machine and metabolic enzymes may dominantly contribute to the well

217 Inhibitors of HIF-1 or metabolic enzymes may impair the metabolic flexibility o

218 ulence factors that destroy host tissues and metabolic enzymes might play an important role in invasi

219 The activity of many proteins, including metabolic enzymes, molecular machines, and ion channels,

220 isruption or pharmacologic inhibition of the metabolic enzymes NAD kinase or ketohexokinase was growt

221 onged in a double heterozygous mutant of the metabolic enzyme non-quiescent mutant 1 (NQM1), a paralo

222 The genes coding for the core metabolic enzymes of the photorespiratory pathway that a

223 ensively analyzed the expression of the main metabolic enzymes of the polyamine pathway and spermine

224 Here we focus on two metabolic enzymes of the yeast S. cerevisiae, neutral tr

225 damide (AEA) and 2-arachidonoylglycerol, and metabolic enzymes of these ligands.

226 Protein complexes of sequential metabolic enzymes, often termed metabolons, may permit d

227 ruvate carboxykinase (PEPCK) is an essential metabolic enzyme operating in the gluconeogenesis and gl

228 ved between plants and microbes are probably metabolic enzymes or transporters; finding functions for

229 ptors that are signal transduction proteins, metabolic enzymes, or permeases involved in nitrogen met

230 ing the question of whether other amino acid metabolic enzymes participate in chromatin regulation.

231 y to investigate the spatial organization of metabolic enzymes participating in glucose metabolism in

232 haperones, antioxidants/detoxifying enzymes, metabolic enzymes, pathogenesis-related proteins, and fl

233 present a computational pipeline to identify metabolic enzymes, pathways, and gene clusters from a se

234 h a direct transcriptional regulation of the metabolic enzyme PFKFB3.

235 in which the protein kinase activity of the metabolic enzyme PGK1 plays an instrumental role and rev

236 Disruption of representative metabolic enzymes phenocopied UPEC DeltaqseC in vivo and

237 ved protein receptors, including the central metabolic enzyme pyruvate carboxylase (LmPC).

238 2017) identify reversible aggregation of the metabolic enzyme pyruvate kinase under environmental str

239 sphorylation-dependent regulation of the key metabolic enzyme, pyruvate dehydrogenase.

240 Moreover, we show that the metabolic enzyme, pyruvate kinase muscle (PKM), interact

241 erging evidence indicates that nonglycolytic metabolic enzymes regulating diverse pathways can assemb

242 tional regulation for the rhythmic gating of metabolic enzymes remains elusive.

243 e for Mannose phosphate isomerase (MPI) as a metabolic enzyme required to maintain Warburg metabolism

244 f-function and gain-of-function mutations of metabolic enzymes, respectively.

245 hosphoglycerate dehydrogenase (PHGDH) is the metabolic enzyme responsible for shunting the glycolytic

246 stablished, the role of miRNAs in regulating metabolic enzymes responsible for RA abundance during ax

247 vide evidence that PPIs, together with their metabolic enzymes SAC2-SAC5, are crucial for vacuolar tr

248 bolic Enzyme complex), which contains serine metabolic enzymes, SAM (S-adenosylmethionine) synthetase

249 ation for understanding how mutations in the metabolic enzymes SDH, FH, and IDH can result in cancer

250 hat this organism regulate expression of key metabolic enzymes so that they are present when environm

251 Regulatory proteins, metabolic enzymes, some myofibrillar and blood plasma pr

252 tylation level and enzymatic activity of key metabolic enzymes, such as acetyl-CoA synthetase, long-c

253 similar in structure to cofactors in modern metabolic enzymes, suggesting a possible abiotic origin

254 nce in mice but does not relieve CCR of most metabolic enzymes, suggesting CcpA-independent CCR mecha

255 phosphoglycerate dehydrogenase (PHGDH), the metabolic enzyme that catalyses the reaction that divert

256 kat-1 encodes a conserved metabolic enzyme that catalyzes the last step of fatty a

257 ing glutamate dehydrogenase (GDH), a 336-kDa metabolic enzyme that catalyzes the oxidative deaminatio

258 Here we report that PHGDH, the key metabolic enzyme that catalyzes the rate-limiting step o

259 chorismate mutase (CM), a well-characterized metabolic enzyme that catalyzes the rearrangement of cho

260 e selective inhibition of a highly conserved metabolic enzyme that contains identical active site res

261 f carnitine palmitoyl transferase (CPT1a), a metabolic enzyme that controls the rate-limiting step to

262 Choline kinase-alpha (ChoKalpha) is a metabolic enzyme that has a role in cell proliferation a

263 nto the mutational landscape of an important metabolic enzyme that is highly conserved throughout euk

264 rol 24S-hydroxylase (Cyp46) is a cholesterol metabolic enzyme that is increased after TBI.

265 osphate dehydrogenase (GAPDH) is an abundant metabolic enzyme that is recruited to the replicase comp

266 Pyruvate kinase M2 (PKM2) is a metabolic enzyme that plays important roles in both proc

267 We identify two additional sphingolipid metabolic enzymes that are concentrated at presynaptic t

268 Transcription-related factors and metabolic enzymes that are expressed in all tissues have

269 ehydrogenase 1 and 2 (IDH1 and IDH2) are key metabolic enzymes that are mutated in a variety of cance

270 Given that Tup1 and the metabolic enzymes that control PI(3,5)P2 are highly cons

271 ar cloning to insecticide targets and to the metabolic enzymes that degrade insecticides before they

272 nophosphate dehydrogenase (IMPDH) are purine metabolic enzymes that function maintaining the cellular

273 ssociated with elevated activities of muscle metabolic enzymes that influence flux through fatty-acid

274 Cytochrome P450 enzymes (P450s) are metabolic enzymes that process the majority of FDA-appro

275 rogenases (MDH and LDH) are homologous, core metabolic enzymes that share a fold and catalytic mechan

276 nhanced the translation of mRNAs for several metabolic enzymes, thereby increasing glycolysis and oxi

277 tochastic catalytic turnovers of a monomeric metabolic enzyme (Thermomyces lanuginosus Lipase) while

278 ties to heat stress, providing evidence that metabolic enzyme thermostability is rate-limiting at sup

279 nfolding stress, and inactivation of crucial metabolic enzymes through S-allylmercapto modification o

280 that GlpR controls both fructose and glucose metabolic enzymes through transcriptional repression of

281 Mapping the cellular distribution of metabolic enzymes thus identifies pathways for regulatin

282 e strongest associations is the tendency for metabolic enzymes to form dihedral complexes, which we s

283 tabolic pathways by coupling the turnover of metabolic enzymes to the levels of key metabolites.

284 includes eCB compounds and their associated metabolic enzymes, together with cannabinoid receptors,

285 variety of paths taken by duplicated primary metabolic enzymes toward integration into specialized me

286 ntaining H2O2-sensitive cysteines, including metabolic enzymes, transcription factors, and uncharacte

287 ogene family members, such as RAP2A, and the metabolic enzyme TYMS; and association of vasogenic edem

288 uld help dissect the roles of this important metabolic enzyme under different environmental and dieta

289 Several metabolic enzymes undergo reversible polymerization into

290 the cell and modulate the activities of key metabolic enzymes via protein deacylation.

291 on factor Hnf4a to DNAs encoding several key metabolic enzymes was reduced in KO mice, suggesting tha

292 while diverse mitochondrial genes and other metabolic enzymes were down-regulated.

293 Metabolic enzymes were largely unchanged despite varied

294 origenesis and increased levels of these two metabolic enzymes, whereas patients with low levels of P

295 an indirect promiscuous replacement of a key metabolic enzyme, which would have been extremely diffic

296 nes, 18 ripening related genes, and 7 starch metabolic enzymes, which are involved as nutrition stora

297 cts are synthesized in plants by specialized metabolic enzymes, which are often lineage-specific and

298 Bioinformatic analysis revealed that metabolic enzymes, which either utilize or generate acet

299 Sphingosine kinase (SphK) is a sphingolipid metabolic enzyme whose activity-dependent recruitment to

300 , Trypanosoma brucei, compartmentalizes some metabolic enzymes within peroxisome-like organelles call