ライフサイエンスコーパス: metabolic flexibility

1 he PDK isoform that is a potent modulator of metabolic flexibility.

2 lular energy metabolism, suggesting neuronal metabolic flexibility.

3 sired metabolic cross-talk while maintaining metabolic flexibility.

4 acyclic terpenes, suggesting a reduction of metabolic flexibility.

5 hways, and improving insulin sensitivity and metabolic flexibility.

6 rs from metabolic bystander to key driver of metabolic flexibility.

7 in the fed state, contributing to a loss of metabolic flexibility.

8 r to IPGR, but less active while maintaining metabolic flexibility.

9 activity levels are a primary determinant of metabolic flexibility.

10 reby allowing the heart to maintain its full metabolic flexibility.

11 ulin sensitive, and active while maintaining metabolic flexibility.

12 is for how NAD(+) homeostasis factors confer metabolic flexibility.

13 nsulin and positively correlated with IS and metabolic flexibility.

14 e context of cellular thiamine synthesis and metabolic flexibility.

15 mental approaches to studying the concept of metabolic flexibility across a range of activity and ina

16 However, the key determinants of metabolic flexibility among relevant clinical population

17 ompensatory fashion, which may contribute to metabolic flexibility and a growth advantage to sustain

18 es a potential mechanism for the increase in metabolic flexibility and enhanced insulin sensitivity p

19 Metabolic flexibility and glucose flux were examined in

20 High fat feeding impairs skeletal muscle metabolic flexibility and induces insulin resistance, wh

21 tine production is essential for maintaining metabolic flexibility and insulin sensitivity.

22 ibility was inversely correlated with IS and metabolic flexibility and positively correlated with bod

23 e sedentary behaviours as therapy to improve metabolic flexibility and reduce weight gain risk.

24 dial glucose uptake and oxidation reduce the metabolic flexibility and render the heart susceptible t

25 because of their small genome size, reduced metabolic flexibility, and high worldwide abundance in f

26 re, BEZ-treated mice also exhibited improved metabolic flexibility as well as an enhanced mitochondri

27 sion of pyruvate transport induces a form of metabolic flexibility associated with the use of lipids

28 organisms that have substantial genetic and metabolic flexibility, can resist multiple classes of an

29 e most salient feature of the network is the metabolic flexibility demonstrated in response to variou

30 and aquatic) green alga that has significant metabolic flexibility for balancing redox equivalents an

31 This alga shows an enormous metabolic flexibility, growing either photoautotrophical

32 Laboratory assessment of metabolic flexibility has traditionally involved measure

33 RYGB surgery results in improved metabolic flexibility (ie, greater disposal of glucose a

34 Metabolic flexibility in fuel use observed in obese chil

35 al muscle mitochondrial substrate choice and metabolic flexibility in part by regulating PDH function

36 We examined individual variation in metabolic flexibility in response to changing food level

37 Metabolic flexibility is defined as the ability to adapt

38 mulate physiological cardiac remodeling, and metabolic flexibility is important for maintaining mitoc

39 Metabolic flexibility is the key to the ecological succe

40 This metabolic flexibility likely explains the success of din

41 t-chain alkane metabolism suggests that such metabolic flexibility may be important in many environme

42 Genetic determinants limiting this "metabolic flexibility" may contribute to insulin resista

43 cular dissection of its functions, providing metabolic flexibility needed for dietary adaptation.

44 Insulin sensitivity (IS) and metabolic flexibility of 16 healthy, young male subjects

45 t adiponectin is a factor that increases the metabolic flexibility of adipose tissue, enhancing its a

46 This study unravelled an unexpected metabolic flexibility of aerobic methanotrophs, thereby

47 These results illustrate the marked metabolic flexibility of C. reinhardtii and contribute t

48 of HIF-1 or metabolic enzymes may impair the metabolic flexibility of cancer cells and make them more

49 The metabolic flexibility of Chlamydomonas offers a unique o

50 olved in their metabolism are crucial to the metabolic flexibility of G. sulphuraria.

51 res and the protein complement highlight the metabolic flexibility of Picochlorum SE3 that encodes ge

52 Metabolic flexibility of skeletal muscle, that is, the p

53 To evaluate the metabolic flexibility of syntrophic Desulfovibrio to ada

54 elative to fatty acids, thereby limiting the metabolic flexibility of the heart that is critically in

55 Relieving this inhibition can increase the metabolic flexibility of the hyperthyroid heart and redu

56 reservoir for tumour cells highlighting the metabolic flexibility of this cancer.

57 ate, intramuscular triglyceride content, and metabolic flexibility (P = 0.016-0.048; n = 178).

58 Metabolic flexibility seems to be reduced as a result of

59 s and laboratory experiments revealed a high metabolic flexibility, suggesting a considerable capacit

60 n a persistent adult phenotype with improved metabolic flexibility that prevents DIO.

61 demonstrate that the diabetic heart retains metabolic flexibility to adapt to hypoxia, but is hinder

62 In conclusion, type 2 diabetic hearts retain metabolic flexibility to adapt to hypoxia, with normal H

63 Metabolic flexibility to glucose (change in respiratory

64 Therefore, we compared metabolic flexibility to glucose adjusted for glucose di

65 Additionally, the increase in metabolic flexibility to glucose after weight loss was a

66 The impaired metabolic flexibility to glucose observed in type 2 diab

67 using different nutrient sources, cells gain metabolic flexibility to survive periods of starvation.

68 Metabolic flexibility was measured in young sedentary me

69 In vivo, metabolic flexibility was positively correlated with IS

70 connection between phenotypic switching and metabolic flexibility, where metabolic specialization of

71 g had no effect on weight gain but increased metabolic flexibility while reducing body fat and liver

72 hat high levels of physical activity predict metabolic flexibility, while physical inactivity and sed

73 of plasma glucose and insulin, and a loss of metabolic flexibility with decreased lipid oxidation.

74 s are equipped with a somewhat unappreciated metabolic flexibility with important implications for th

75 eliminating glucotoxicity, which reinstates metabolic flexibility with restored preprandial lipid ox

76 The aged heart exhibits impaired metabolic flexibility, with a decreased capacity to oxid

77 Our results highlight the metabolic flexibility within the isoflavonoid pathway, s

78 At the same time, a great potential for metabolic flexibility within this group is uncovered, wi